Mus musculus

94 known processes

Elane

elastase, neutrophil expressed

(Aliases: F430011M15Rik,Ela2,NE)

Elane biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
killing by host of symbiont cells GO:0051873 11 0.865
growth involved in symbiotic interaction GO:0044110 23 0.660
defense response to gram positive bacterium GO:0050830 50 0.648
leukocyte mediated immunity GO:0002443 174 0.647
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.624
defense response to bacterium GO:0042742 119 0.575
Human
cytokine production GO:0001816 319 0.457
Human
negative regulation of phagocytosis GO:0050765 4 0.451
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.411
interaction with symbiont GO:0051702 14 0.404
immune effector process GO:0002252 321 0.391
regulation of protein serine threonine kinase activity GO:0071900 157 0.360
leukocyte migration GO:0050900 124 0.354
negative regulation of growth of symbiont in host GO:0044130 19 0.354
disruption by host of symbiont cells GO:0051852 11 0.347
regulation of cellular amine metabolic process GO:0033238 20 0.343
defense response to fungus GO:0050832 12 0.343
defense response to other organism GO:0098542 197 0.337
inflammatory response GO:0006954 244 0.330
regulation of growth of symbiont in host GO:0044126 19 0.325
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.312
acute inflammatory response to antigenic stimulus GO:0002438 12 0.309
positive regulation of cytokine production GO:0001819 174 0.300
Human
growth of symbiont in host GO:0044117 23 0.287
regulation of angiotensin levels in blood GO:0002002 4 0.278
regulation of cytokine production GO:0001817 266 0.277
Human
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.271
leukocyte differentiation GO:0002521 342 0.264
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.248
regulation of interleukin 8 production GO:0032677 3 0.244
Human
fat cell differentiation GO:0045444 160 0.242
cellular amine metabolic process GO:0044106 44 0.228
interspecies interaction between organisms GO:0044419 83 0.228
amine metabolic process GO:0009308 45 0.220
regulation of multi organism process GO:0043900 111 0.219
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.218
killing of cells of other organism GO:0031640 13 0.215
mature dendritic cell differentiation GO:0097029 3 0.210
humoral immune response GO:0006959 57 0.206
negative regulation of multi organism process GO:0043901 68 0.203
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.197
cellular ketone metabolic process GO:0042180 84 0.196
regulation of cellular amino acid metabolic process GO:0006521 5 0.195
regulation of protein kinase activity GO:0045859 232 0.192
growth of symbiont involved in interaction with host GO:0044116 23 0.184
negative regulation of cytokine production GO:0001818 84 0.180
Human
skeletal system development GO:0001501 356 0.173
ion transmembrane transport GO:0034220 361 0.171
sensory organ morphogenesis GO:0090596 242 0.169
lymphocyte mediated immunity GO:0002449 139 0.162
positive regulation of protein phosphorylation GO:0001934 242 0.161
myeloid leukocyte differentiation GO:0002573 119 0.160
positive regulation of cellular amine metabolic process GO:0033240 5 0.157
regulation of fat cell differentiation GO:0045598 81 0.156
glycoprotein metabolic process GO:0009100 116 0.156
myeloid cell differentiation GO:0030099 233 0.152
response to organonitrogen compound GO:0010243 246 0.152
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.149
cation homeostasis GO:0055080 212 0.142
leukocyte proliferation GO:0070661 172 0.141
striated muscle tissue development GO:0014706 293 0.136
regulation of adaptive immune response GO:0002819 90 0.133
negative regulation of interleukin 5 production GO:0032714 4 0.131
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.130
negative regulation of growth GO:0045926 99 0.128
cation transport GO:0006812 399 0.127
defense response to nematode GO:0002215 4 0.127
regulation of cellular ketone metabolic process GO:0010565 66 0.119
cell killing GO:0001906 67 0.119
innate immune response in mucosa GO:0002227 3 0.113
iron ion homeostasis GO:0055072 36 0.113
neutrophil mediated immunity GO:0002446 19 0.112
adaptive immune response GO:0002250 155 0.111
t cell mediated immunity GO:0002456 50 0.109
cell substrate adhesion GO:0031589 130 0.108
positive regulation of protein kinase activity GO:0045860 144 0.107
regulation of lymphocyte activation GO:0051249 240 0.106
t cell activation GO:0042110 289 0.101
mapk cascade GO:0000165 281 0.101
regulation of cell activation GO:0050865 289 0.101
regulation of map kinase activity GO:0043405 120 0.098
angiogenesis GO:0001525 201 0.097
ensheathment of neurons GO:0007272 76 0.097
blood coagulation GO:0007596 76 0.094
hydrogen peroxide catabolic process GO:0042744 5 0.089
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.088
leukocyte mediated cytotoxicity GO:0001909 62 0.085
negative regulation of protein metabolic process GO:0051248 282 0.083
Human
cellular response to hormone stimulus GO:0032870 150 0.082
epithelial tube morphogenesis GO:0060562 303 0.082
production of molecular mediator of immune response GO:0002440 103 0.080
regulation of protein localization GO:0032880 231 0.080
activation of mapk activity GO:0000187 59 0.080
lymphocyte proliferation GO:0046651 164 0.079
phagocytosis GO:0006909 66 0.078
cytokine secretion GO:0050663 72 0.078
blood circulation GO:0008015 195 0.078
forebrain development GO:0030900 302 0.076
positive regulation of transferase activity GO:0051347 167 0.076
regulation of protein transport GO:0051223 163 0.076
positive regulation of protein transport GO:0051222 93 0.074
positive regulation of protein modification process GO:0031401 299 0.074
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.074
regulation of t cell costimulation GO:2000523 2 0.073
nitrogen compound transport GO:0071705 271 0.073
lymphocyte differentiation GO:0030098 242 0.072
retina development in camera type eye GO:0060041 119 0.072
regulation of angiotensin metabolic process GO:0060177 4 0.072
regulation of chemokine production GO:0032642 30 0.072
Human
platelet activation GO:0030168 40 0.070
response to lipopolysaccharide GO:0032496 128 0.070
eosinophil migration GO:0072677 3 0.070
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.070
organonitrogen compound biosynthetic process GO:1901566 192 0.069
negative regulation of cell activation GO:0050866 111 0.068
g protein coupled receptor signaling pathway GO:0007186 243 0.067
negative regulation of cell proliferation GO:0008285 296 0.066
skin development GO:0043588 220 0.065
regulation of establishment of protein localization GO:0070201 181 0.065
regulation of engulfment of apoptotic cell GO:1901074 2 0.065
metal ion homeostasis GO:0055065 189 0.064
regulation of cellular response to stress GO:0080135 159 0.064
cell adhesion GO:0007155 329 0.064
action potential GO:0001508 78 0.064
cellular chemical homeostasis GO:0055082 215 0.064
response to oxygen radical GO:0000305 16 0.064
bone development GO:0060348 120 0.063
cellular amino acid metabolic process GO:0006520 103 0.063
ossification GO:0001503 216 0.062
regulation of response to wounding GO:1903034 189 0.061
smooth muscle contraction GO:0006939 44 0.061
muscle tissue development GO:0060537 308 0.061
cellular response to organonitrogen compound GO:0071417 145 0.060
response to light stimulus GO:0009416 135 0.060
Human
membrane organization GO:0061024 245 0.059
carbohydrate metabolic process GO:0005975 230 0.059
regulation of anatomical structure size GO:0090066 178 0.058
divalent inorganic cation transport GO:0072511 178 0.058
regulation of leukocyte mediated immunity GO:0002703 104 0.058
response to decreased oxygen levels GO:0036293 59 0.058
monocarboxylic acid metabolic process GO:0032787 191 0.056
response to molecule of bacterial origin GO:0002237 143 0.056
regulation of kinase activity GO:0043549 249 0.055
myeloid leukocyte migration GO:0097529 57 0.055
blood vessel morphogenesis GO:0048514 285 0.054
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.054
positive regulation of monocyte chemotaxis GO:0090026 2 0.053
wound healing GO:0042060 157 0.053
calcium ion homeostasis GO:0055074 127 0.052
regulation of body fluid levels GO:0050878 162 0.051
organic hydroxy compound metabolic process GO:1901615 203 0.050
positive regulation of acute inflammatory response to non antigenic stimulus GO:0002879 2 0.050
chemotaxis GO:0006935 247 0.049
neutrophil mediated killing of fungus GO:0070947 3 0.049
modification of morphology or physiology of other organism GO:0035821 18 0.049
regulation of inflammatory response GO:0050727 147 0.049
renin angiotensin regulation of aldosterone production GO:0002018 3 0.048
positive regulation of mapk cascade GO:0043410 170 0.048
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.048
immune response regulating signaling pathway GO:0002764 125 0.048
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.048
regulation of lymphocyte mediated immunity GO:0002706 84 0.047
cellular ion homeostasis GO:0006873 165 0.046
t cell differentiation in thymus GO:0033077 77 0.046
peptidyl amino acid modification GO:0018193 336 0.046
endocytosis GO:0006897 168 0.045
detection of light stimulus GO:0009583 25 0.045
amide transport GO:0042886 138 0.045
multicellular organismal metabolic process GO:0044236 28 0.045
innate immune response GO:0045087 157 0.044
tissue homeostasis GO:0001894 115 0.044
t helper 17 cell chemotaxis GO:0035705 1 0.044
muscle cell differentiation GO:0042692 261 0.044
gland development GO:0048732 330 0.044
regulation of cytokine biosynthetic process GO:0042035 59 0.044
Human
positive regulation of lymphocyte activation GO:0051251 140 0.044
anatomical structure homeostasis GO:0060249 145 0.044
ear morphogenesis GO:0042471 118 0.044
epithelial cell proliferation GO:0050673 174 0.043
cytoplasmic transport GO:0016482 234 0.043
regulation of mapk cascade GO:0043408 248 0.042
regulation of apoptotic signaling pathway GO:2001233 197 0.042
response to extracellular stimulus GO:0009991 127 0.042
locomotory behavior GO:0007626 195 0.041
proteoglycan metabolic process GO:0006029 38 0.041
regulation of secretion GO:0051046 274 0.041
negative regulation of defense response GO:0031348 77 0.041
carbohydrate derivative biosynthetic process GO:1901137 183 0.040
cellular response to lipid GO:0071396 145 0.040
regulation of hormone levels GO:0010817 211 0.040
hemostasis GO:0007599 78 0.040
response to steroid hormone GO:0048545 56 0.039
regulation of defense response GO:0031347 233 0.039
keratinocyte migration GO:0051546 3 0.039
regulation of t cell proliferation GO:0042129 92 0.039
activation of adenylate cyclase activity GO:0007190 4 0.038
cellular calcium ion homeostasis GO:0006874 119 0.038
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.038
compound eye development GO:0048749 1 0.038
positive regulation of t cell extravasation GO:2000409 2 0.037
ear development GO:0043583 200 0.037
interleukin 12 secretion GO:0072610 3 0.037
response to growth factor GO:0070848 198 0.037
positive regulation of cytokine secretion GO:0050715 41 0.037
positive regulation of apoptotic process GO:0043065 217 0.037
trabecula formation GO:0060343 24 0.037
sensory perception GO:0007600 245 0.036
positive regulation of vasoconstriction GO:0045907 4 0.036
regulation of membrane potential GO:0042391 192 0.036
small gtpase mediated signal transduction GO:0007264 97 0.036
positive regulation of cytokine biosynthetic process GO:0042108 40 0.036
Human
disruption of cells of other organism GO:0044364 13 0.036
regulation of cell projection assembly GO:0060491 38 0.036
regulation of transferase activity GO:0051338 263 0.035
skeletal muscle organ development GO:0060538 163 0.035
actin filament organization GO:0007015 113 0.035
defense response to gram negative bacterium GO:0050829 28 0.035
multicellular organismal signaling GO:0035637 91 0.035
antimicrobial peptide biosynthetic process GO:0002777 2 0.035
removal of superoxide radicals GO:0019430 12 0.035
intracellular protein transport GO:0006886 204 0.034
telencephalon development GO:0021537 186 0.034
regulation of jnk cascade GO:0046328 62 0.034
regulation of interleukin 4 production GO:0032673 18 0.034
positive regulation of map kinase activity GO:0043406 84 0.034
striated muscle adaptation GO:0014888 26 0.034
cytokine metabolic process GO:0042107 71 0.034
Human
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.033
regulation of t cell activation GO:0050863 170 0.033
peptidyl tyrosine phosphorylation GO:0018108 143 0.033
acetylcholine secretion neurotransmission GO:0014055 2 0.033
regulation of microvillus assembly GO:0032534 3 0.033
regulation of t cell mediated immunity GO:0002709 34 0.033
central nervous system maturation GO:0021626 6 0.032
wnt signaling pathway GO:0016055 188 0.032
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.032
positive regulation of phospholipase c activity GO:0010863 2 0.032
protein localization to organelle GO:0033365 185 0.032
negative regulation of lymphocyte proliferation GO:0050672 45 0.032
negative regulation of leukocyte proliferation GO:0070664 46 0.032
regulation of interleukin 10 production GO:0032653 21 0.032
positive regulation of immune effector process GO:0002699 107 0.032
muscle cell development GO:0055001 133 0.032
homeostasis of number of cells GO:0048872 210 0.032
interleukin 4 production GO:0032633 24 0.031
negative regulation of response to wounding GO:1903035 77 0.031
positive regulation of cell activation GO:0050867 158 0.031
regulation of cell motility GO:2000145 236 0.031
cellular homeostasis GO:0019725 240 0.031
organophosphate biosynthetic process GO:0090407 122 0.031
positive regulation of immunological synapse formation GO:2000522 1 0.031
visual perception GO:0007601 52 0.031
ammonium transmembrane transport GO:0072488 2 0.031
regulation of neuron death GO:1901214 134 0.031
morphogenesis of embryonic epithelium GO:0016331 159 0.031
lipoxin a4 biosynthetic process GO:2001303 1 0.030
glycerolipid metabolic process GO:0046486 122 0.030
sensory perception of light stimulus GO:0050953 54 0.030
microtubule cytoskeleton organization GO:0000226 157 0.030
regulation of blood pressure GO:0008217 93 0.030
i kappab kinase nf kappab signaling GO:0007249 85 0.030
regulation of cytokine secretion GO:0050707 61 0.030
negative regulation of cellular component organization GO:0051129 194 0.030
positive regulation of epithelial cell proliferation GO:0050679 68 0.030
carbohydrate biosynthetic process GO:0016051 74 0.030
activation of immune response GO:0002253 138 0.029
cellular response to oxidative stress GO:0034599 76 0.029
positive regulation of histone h3 k9 methylation GO:0051574 4 0.029
positive regulation of kinase activity GO:0033674 155 0.029
reactive oxygen species biosynthetic process GO:1903409 8 0.029
muscle fiber development GO:0048747 76 0.029
regulation of monocyte chemotaxis GO:0090025 3 0.029
response to peptide GO:1901652 136 0.028
response to nutrient levels GO:0031667 109 0.028
response to insulin GO:0032868 100 0.028
tube formation GO:0035148 140 0.028
regulation of cellular component biogenesis GO:0044087 181 0.028
erythrocyte differentiation GO:0030218 88 0.028
cellular response to superoxide GO:0071451 14 0.028
stem cell development GO:0048864 219 0.028
tissue remodeling GO:0048771 102 0.027
eosinophil activation GO:0043307 1 0.027
transmembrane transport GO:0055085 412 0.027
cellular response to dna damage stimulus GO:0006974 207 0.027
muscle hypertrophy GO:0014896 24 0.027
organelle assembly GO:0070925 177 0.027
cell type specific apoptotic process GO:0097285 268 0.027
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.026
positive regulation of lymphocyte proliferation GO:0050671 70 0.026
myelination GO:0042552 74 0.026
activation of innate immune response GO:0002218 56 0.026
striated muscle cell development GO:0055002 125 0.026
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.026
leukotriene metabolic process GO:0006691 7 0.026
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
sulfur compound metabolic process GO:0006790 100 0.026
t cell differentiation GO:0030217 174 0.026
cellular response to amino acid stimulus GO:0071230 29 0.025
response to acid chemical GO:0001101 111 0.025
germ cell development GO:0007281 185 0.025
cellular metal ion homeostasis GO:0006875 151 0.025
jnk cascade GO:0007254 72 0.025
regulation of microvillus organization GO:0032530 3 0.025
skeletal system morphogenesis GO:0048705 203 0.025
response to organic cyclic compound GO:0014070 198 0.025
ameboidal type cell migration GO:0001667 128 0.025
acetylcholine transport GO:0015870 2 0.025
positive regulation of cell motility GO:2000147 116 0.024
skeletal muscle fiber development GO:0048741 58 0.024
regulation of phagocytosis GO:0050764 33 0.024
lipid biosynthetic process GO:0008610 179 0.024
myeloid leukocyte mediated immunity GO:0002444 42 0.024
glucose metabolic process GO:0006006 92 0.024
transition metal ion homeostasis GO:0055076 54 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
response to peptide hormone GO:0043434 127 0.024
regulation of carbohydrate metabolic process GO:0006109 75 0.024
regulation of leukocyte proliferation GO:0070663 121 0.024
muscle system process GO:0003012 141 0.024
regulation of chloride transport GO:2001225 2 0.024
regulation of cell projection organization GO:0031344 206 0.024
positive regulation of fat cell differentiation GO:0045600 32 0.024
interleukin 10 production GO:0032613 23 0.024
neuron apoptotic process GO:0051402 142 0.024
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.024
macromolecule catabolic process GO:0009057 281 0.024
vascular process in circulatory system GO:0003018 62 0.024
negative regulation of lymphocyte activation GO:0051250 91 0.024
antigen processing and presentation of peptide antigen GO:0048002 29 0.024
epithelial tube formation GO:0072175 130 0.023
eosinophil differentiation GO:0030222 1 0.023
peptidyl tyrosine modification GO:0018212 145 0.023
regulation of neuron apoptotic process GO:0043523 122 0.023
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.023
cofactor transport GO:0051181 4 0.023
ceramide biosynthetic process GO:0046513 20 0.023
endochondral bone morphogenesis GO:0060350 50 0.023
positive regulation of innate immune response GO:0045089 80 0.023
cardiac muscle tissue development GO:0048738 130 0.023
ribose phosphate biosynthetic process GO:0046390 59 0.023
organ regeneration GO:0031100 2 0.023
amino sugar catabolic process GO:0046348 1 0.023
regulation of endopeptidase activity GO:0052548 89 0.023
protein targeting GO:0006605 143 0.023
neural precursor cell proliferation GO:0061351 121 0.023
microglial cell activation involved in immune response GO:0002282 1 0.023
stress activated protein kinase signaling cascade GO:0031098 81 0.023
digestive system development GO:0055123 200 0.023
fatty acid biosynthetic process GO:0006633 41 0.023
regulation of proteolysis GO:0030162 164 0.023
neuronal action potential GO:0019228 54 0.023
lipoprotein metabolic process GO:0042157 43 0.023
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.023
positive regulation of stress activated mapk cascade GO:0032874 48 0.023
regulation of vesicle mediated transport GO:0060627 139 0.023
transmission of nerve impulse GO:0019226 76 0.022
antigen processing and presentation of exogenous antigen GO:0019884 26 0.022
response to radiation GO:0009314 165 0.022
Human
mechanoreceptor differentiation GO:0042490 67 0.022
neutrophil mediated killing of symbiont cell GO:0070943 8 0.022
phospholipid transfer to membrane GO:0006649 2 0.022
glycoprotein biosynthetic process GO:0009101 89 0.022
protein secretion GO:0009306 111 0.022
head morphogenesis GO:0060323 34 0.022
hematopoietic stem cell migration GO:0035701 1 0.022
regulation of stress activated mapk cascade GO:0032872 69 0.022
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.022
negative regulation of immune effector process GO:0002698 55 0.022
positive regulation of secretion by cell GO:1903532 114 0.022
iron ion transport GO:0006826 17 0.022
neuron death GO:0070997 154 0.021
negative regulation of neuron apoptotic process GO:0043524 92 0.021
tumor necrosis factor production GO:0032640 50 0.021
stem cell differentiation GO:0048863 268 0.021
cellular response to interleukin 15 GO:0071350 2 0.021
interleukin 8 production GO:0032637 4 0.021
Human
protein maturation GO:0051604 176 0.021
negative regulation of interleukin 13 production GO:0032696 2 0.021
phenol containing compound metabolic process GO:0018958 60 0.021
regulation of epithelial cell proliferation GO:0050678 141 0.021
connective tissue development GO:0061448 179 0.021
fucosylation GO:0036065 9 0.021
negative regulation of neuron death GO:1901215 98 0.021
metencephalon development GO:0022037 89 0.021
response to inorganic substance GO:0010035 96 0.021
cytosolic calcium ion homeostasis GO:0051480 70 0.021
acute inflammatory response GO:0002526 41 0.021
nucleotide metabolic process GO:0009117 332 0.021
nuclear transport GO:0051169 139 0.021
purine ribonucleotide biosynthetic process GO:0009152 59 0.021
interleukin 1 secretion GO:0050701 16 0.020
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.020
response to mineralocorticoid GO:0051385 1 0.020
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.020
ovulation cycle GO:0042698 59 0.020
axonogenesis GO:0007409 274 0.020
cellular response to growth factor stimulus GO:0071363 197 0.020
interleukin 5 production GO:0032634 10 0.020
regulation of granulocyte chemotaxis GO:0071622 17 0.020
central nervous system neuron differentiation GO:0021953 162 0.020
myotube differentiation GO:0014902 105 0.020
positive regulation of cell migration GO:0030335 109 0.020
cartilage development GO:0051216 140 0.019
response to oxygen levels GO:0070482 62 0.019
vasodilation GO:0042311 28 0.019
bone morphogenesis GO:0060349 78 0.019
cardiac ventricle morphogenesis GO:0003208 50 0.019
cell matrix adhesion GO:0007160 68 0.019
heart morphogenesis GO:0003007 178 0.019
positive regulation of granulocyte chemotaxis GO:0071624 12 0.019
nucleoside phosphate biosynthetic process GO:1901293 79 0.019
bone trabecula morphogenesis GO:0061430 12 0.019
hexose metabolic process GO:0019318 98 0.019
cellular response to peptide GO:1901653 92 0.019
response to oxidative stress GO:0006979 123 0.019
pallium development GO:0021543 120 0.019
cation transmembrane transport GO:0098655 266 0.019
positive regulation of defense response GO:0031349 124 0.019
muscle contraction GO:0006936 101 0.019
positive regulation of interleukin 4 production GO:0032753 15 0.019
regulation of leukocyte apoptotic process GO:2000106 56 0.019
monocarboxylic acid biosynthetic process GO:0072330 61 0.018
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.018
positive regulation of jun kinase activity GO:0043507 30 0.018
microtubule based process GO:0007017 236 0.018
inorganic anion transport GO:0015698 43 0.018
protein ubiquitination GO:0016567 171 0.018
regulation of ion transport GO:0043269 215 0.018
appendage development GO:0048736 166 0.018
regulation of cell substrate adhesion GO:0010810 73 0.018
t cell mediated cytotoxicity GO:0001913 26 0.018
morphogenesis of a branching epithelium GO:0061138 193 0.018
eosinophil mediated immunity GO:0002447 1 0.018
cellular response to oxygen radical GO:0071450 14 0.018
positive regulation of response to wounding GO:1903036 66 0.018
kidney development GO:0001822 213 0.018
cardiac chamber morphogenesis GO:0003206 93 0.018
lipoxygenase pathway GO:0019372 5 0.018
replacement ossification GO:0036075 26 0.018
myotube cell development GO:0014904 60 0.018
macromolecule methylation GO:0043414 120 0.018
camera type eye development GO:0043010 266 0.018
synapse organization GO:0050808 125 0.018
protein lipidation GO:0006497 28 0.018
cytokine production involved in immune response GO:0002367 34 0.017
positive regulation of monocyte extravasation GO:2000439 1 0.017
regulation of immunoglobulin mediated immune response GO:0002889 37 0.017
immune complex clearance by monocytes and macrophages GO:0002436 2 0.017
b cell proliferation GO:0042100 53 0.017
cardiac chamber development GO:0003205 108 0.017
regulation of tube size GO:0035150 57 0.017
cell chemotaxis GO:0060326 81 0.017
cytokine biosynthetic process GO:0042089 68 0.017
Human
epithelial cell development GO:0002064 159 0.017
neutrophil mediated cytotoxicity GO:0070942 8 0.017
immunoglobulin mediated immune response GO:0016064 69 0.017
cellular response to nutrient levels GO:0031669 64 0.017
establishment of skin barrier GO:0061436 14 0.017
gonad development GO:0008406 141 0.017
regulation of neutrophil chemotaxis GO:0090022 14 0.017
glucose homeostasis GO:0042593 128 0.017
dendritic cell differentiation GO:0097028 26 0.017
negative regulation of inflammatory response GO:0050728 61 0.017
negative regulation of adaptive immune response GO:0002820 25 0.017
respiratory burst GO:0045730 8 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
leukotriene biosynthetic process GO:0019370 5 0.017
calcium mediated signaling GO:0019722 46 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
regulation of cytoskeleton organization GO:0051493 122 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
regulation of hemostasis GO:1900046 28 0.016
fatty acid derivative biosynthetic process GO:1901570 15 0.016
negative regulation of interleukin 10 production GO:0032693 8 0.016
positive regulation of inflammatory response GO:0050729 47 0.016
lymphocyte apoptotic process GO:0070227 54 0.016

Elane disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.345
Human
disease of anatomical entity DOID:7 0 0.345
Human
hematopoietic system disease DOID:74 0 0.166
Human
blood coagulation disease DOID:1247 0 0.150
inherited blood coagulation disease DOID:2214 0 0.076
hemorrhagic disease DOID:2213 0 0.068
sensory system disease DOID:0050155 0 0.051
eye and adnexa disease DOID:1492 0 0.051
nervous system disease DOID:863 0 0.051
eye disease DOID:5614 0 0.051
blood platelet disease DOID:2218 0 0.048
retinal disease DOID:5679 0 0.035
musculoskeletal system disease DOID:17 0 0.032
connective tissue disease DOID:65 0 0.032
osteochondrodysplasia DOID:2256 0 0.031
bone development disease DOID:0080006 0 0.031
bone disease DOID:0080001 0 0.031
disease of metabolism DOID:0014667 0 0.019
inherited metabolic disorder DOID:655 0 0.019