Mus musculus

20 known processes

Emilin1

elastin microfibril interfacer 1

(Aliases: 5830419M17Rik,gp115,BB105748,EMILIN-1,AW229038)

Emilin1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein hydroxylation GO:0018126 4 0.427
blood vessel morphogenesis GO:0048514 285 0.380
extracellular structure organization GO:0043062 148 0.299
extracellular matrix organization GO:0030198 147 0.221
extrinsic apoptotic signaling pathway GO:0097191 126 0.213
small gtpase mediated signal transduction GO:0007264 97 0.203
cellular amino acid metabolic process GO:0006520 103 0.202
peptidyl proline hydroxylation GO:0019511 3 0.181
response to amino acid GO:0043200 37 0.162
oxidation reduction process GO:0055114 342 0.148
angiogenesis GO:0001525 201 0.147
cellular response to amino acid stimulus GO:0071230 29 0.130
regulation of cell motility GO:2000145 236 0.128
skeletal system development GO:0001501 356 0.125
cellular response to organonitrogen compound GO:0071417 145 0.124
cell matrix adhesion GO:0007160 68 0.109
cell substrate adhesion GO:0031589 130 0.106
regulation of cellular ketone metabolic process GO:0010565 66 0.103
rho protein signal transduction GO:0007266 32 0.103
ras protein signal transduction GO:0007265 77 0.097
response to organonitrogen compound GO:0010243 246 0.096
cell adhesion GO:0007155 329 0.088
multicellular organismal homeostasis GO:0048871 164 0.082
connective tissue development GO:0061448 179 0.080
regulation of cell migration GO:0030334 219 0.078
forebrain development GO:0030900 302 0.076
response to acid chemical GO:0001101 111 0.076
ossification GO:0001503 216 0.075
regulation of cellular amino acid metabolic process GO:0006521 5 0.074
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.074
nucleoside phosphate metabolic process GO:0006753 338 0.071
cellular response to acid chemical GO:0071229 68 0.068
single organism cell adhesion GO:0098602 156 0.067
production of molecular mediator of immune response GO:0002440 103 0.067
muscle tissue development GO:0060537 308 0.067
nucleobase containing small molecule metabolic process GO:0055086 352 0.067
cartilage development GO:0051216 140 0.066
cellular modified amino acid metabolic process GO:0006575 63 0.064
chondrocyte differentiation GO:0002062 72 0.062
collagen fibril organization GO:0030199 32 0.060
male gamete generation GO:0048232 285 0.057
peptidyl amino acid modification GO:0018193 336 0.057
muscle cell differentiation GO:0042692 261 0.056
bone development GO:0060348 120 0.056
spermatogenesis GO:0007283 284 0.052
regulation of cellular response to stress GO:0080135 159 0.052
regulation of secretion GO:0051046 274 0.052
cellular response to lipopolysaccharide GO:0071222 77 0.051
regulation of apoptotic signaling pathway GO:2001233 197 0.050
nucleotide metabolic process GO:0009117 332 0.048
cellular ketone metabolic process GO:0042180 84 0.048
embryonic organ morphogenesis GO:0048562 276 0.048
negative regulation of cellular component organization GO:0051129 194 0.048
apoptotic signaling pathway GO:0097190 306 0.046
negative regulation of cell development GO:0010721 169 0.046
cellular response to abiotic stimulus GO:0071214 56 0.046
chemotaxis GO:0006935 247 0.045
positive regulation of cell development GO:0010720 237 0.044
monocarboxylic acid metabolic process GO:0032787 191 0.044
cellular response to cytokine stimulus GO:0071345 189 0.044
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.043
synaptic transmission GO:0007268 329 0.042
positive regulation of nervous system development GO:0051962 221 0.042
regulation of protein localization GO:0032880 231 0.042
amine metabolic process GO:0009308 45 0.041
ear development GO:0043583 200 0.041
cellular response to oxidative stress GO:0034599 76 0.040
defense response to other organism GO:0098542 197 0.040
striated muscle tissue development GO:0014706 293 0.040
cellular response to external stimulus GO:0071496 88 0.039
negative regulation of nervous system development GO:0051961 156 0.039
signal transduction in absence of ligand GO:0038034 55 0.038
regulation of cellular amine metabolic process GO:0033238 20 0.038
purine containing compound metabolic process GO:0072521 311 0.038
synapse organization GO:0050808 125 0.037
digestive tract development GO:0048565 190 0.037
axonogenesis GO:0007409 274 0.037
negative regulation of cell adhesion GO:0007162 45 0.036
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.036
regulation of ossification GO:0030278 112 0.036
response to inorganic substance GO:0010035 96 0.036
cardiac muscle tissue development GO:0048738 130 0.036
cardiac chamber morphogenesis GO:0003206 93 0.036
limb morphogenesis GO:0035108 149 0.035
appendage morphogenesis GO:0035107 149 0.035
regionalization GO:0003002 337 0.035
cellular response to growth factor stimulus GO:0071363 197 0.034
regulation of rho protein signal transduction GO:0035023 71 0.034
cell cell adhesion GO:0098609 41 0.034
peripheral nervous system axon regeneration GO:0014012 2 0.034
oligosaccharide biosynthetic process GO:0009312 7 0.033
positive regulation of response to wounding GO:1903036 66 0.033
palate development GO:0060021 76 0.033
response to oxygen levels GO:0070482 62 0.032
skeletal system morphogenesis GO:0048705 203 0.032
digestive system development GO:0055123 200 0.032
sensory organ morphogenesis GO:0090596 242 0.032
peptidyl proline modification GO:0018208 6 0.032
ribose phosphate metabolic process GO:0019693 291 0.031
engulfment of apoptotic cell GO:0043652 3 0.031
organonitrogen compound biosynthetic process GO:1901566 192 0.031
regulation of angiogenesis GO:0045765 81 0.031
glycoprotein metabolic process GO:0009100 116 0.031
regulation of neuron projection development GO:0010975 169 0.030
cellular response to hormone stimulus GO:0032870 150 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
regulation of cell projection organization GO:0031344 206 0.030
regulation of ras protein signal transduction GO:0046578 114 0.030
carbohydrate derivative biosynthetic process GO:1901137 183 0.029
regulation of secretion by cell GO:1903530 249 0.028
sensory perception of sound GO:0007605 97 0.028
sensory perception GO:0007600 245 0.028
nitrogen compound transport GO:0071705 271 0.027
regulation of hormone levels GO:0010817 211 0.027
regulation of neuron differentiation GO:0045664 281 0.027
respiratory tube development GO:0030323 167 0.027
nucleoside triphosphate metabolic process GO:0009141 230 0.027
myeloid leukocyte differentiation GO:0002573 119 0.027
inflammatory response GO:0006954 244 0.027
ameboidal type cell migration GO:0001667 128 0.026
negative regulation of immune system process GO:0002683 209 0.026
camera type eye development GO:0043010 266 0.026
response to oxidative stress GO:0006979 123 0.026
regulation of body fluid levels GO:0050878 162 0.026
biomineral tissue development GO:0031214 64 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
regulation of organelle organization GO:0033043 289 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.025
anion transport GO:0006820 177 0.025
purine nucleotide metabolic process GO:0006163 302 0.025
response to molecule of bacterial origin GO:0002237 143 0.025
negative regulation of synapse assembly GO:0051964 3 0.025
regulation of protein transport GO:0051223 163 0.025
response to decreased oxygen levels GO:0036293 59 0.025
tissue homeostasis GO:0001894 115 0.025
positive regulation of apoptotic process GO:0043065 217 0.025
developmental maturation GO:0021700 193 0.025
regulation of cytokine production GO:0001817 266 0.024
wound healing GO:0042060 157 0.024
detection of stimulus GO:0051606 84 0.024
gastrulation GO:0007369 116 0.024
regulation of response to wounding GO:1903034 189 0.024
multicellular organismal catabolic process GO:0044243 7 0.024
muscle cell development GO:0055001 133 0.024
dna metabolic process GO:0006259 303 0.023
skin development GO:0043588 220 0.023
cellular response to lipid GO:0071396 145 0.023
wnt signaling pathway GO:0016055 188 0.023
negative regulation of cell substrate adhesion GO:0010812 16 0.023
gland development GO:0048732 330 0.023
positive regulation of programmed cell death GO:0043068 218 0.023
defense response to virus GO:0051607 68 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
sensory perception of mechanical stimulus GO:0050954 107 0.023
endochondral bone morphogenesis GO:0060350 50 0.022
heart morphogenesis GO:0003007 178 0.022
myeloid cell differentiation GO:0030099 233 0.022
organelle assembly GO:0070925 177 0.022
interspecies interaction between organisms GO:0044419 83 0.021
positive regulation of apoptotic cell clearance GO:2000427 3 0.021
regulation of cellular component biogenesis GO:0044087 181 0.021
protein heterooligomerization GO:0051291 14 0.021
antibacterial peptide secretion GO:0002779 1 0.021
formation of primary germ layer GO:0001704 77 0.021
leukocyte mediated immunity GO:0002443 174 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
regulation of anatomical structure size GO:0090066 178 0.021
cellular response to biotic stimulus GO:0071216 92 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
positive regulation of protein modification process GO:0031401 299 0.020
positive regulation of cell motility GO:2000147 116 0.020
protein catabolic process GO:0030163 221 0.020
leukocyte migration GO:0050900 124 0.020
negative regulation of interleukin 5 production GO:0032714 4 0.020
positive regulation of cell migration GO:0030335 109 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
regulation of system process GO:0044057 200 0.020
smooth muscle tissue development GO:0048745 22 0.020
head morphogenesis GO:0060323 34 0.020
positive regulation of cell death GO:0010942 224 0.020
anatomical structure homeostasis GO:0060249 145 0.020
endothelium development GO:0003158 45 0.019
mesenchymal cell differentiation GO:0048762 107 0.019
regulation of cell adhesion GO:0030155 154 0.019
negative regulation of macrophage chemotaxis GO:0010760 1 0.019
fat cell differentiation GO:0045444 160 0.019
embryonic skeletal system morphogenesis GO:0048704 91 0.019
endocytosis GO:0006897 168 0.019
stem cell development GO:0048864 219 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
aromatic compound catabolic process GO:0019439 286 0.019
purine containing compound catabolic process GO:0072523 213 0.019
cell maturation GO:0048469 127 0.018
intracellular receptor signaling pathway GO:0030522 74 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
peptide metabolic process GO:0006518 46 0.018
protein oligomerization GO:0051259 67 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
cell recognition GO:0008037 83 0.018
epidermis development GO:0008544 187 0.018
regulation of chondrocyte differentiation GO:0032330 33 0.018
neuron migration GO:0001764 122 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
regulation of cell substrate adhesion GO:0010810 73 0.018
response to growth factor GO:0070848 198 0.018
single organismal cell cell adhesion GO:0016337 131 0.018
digestive tract morphogenesis GO:0048546 147 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.017
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
cardiac ventricle development GO:0003231 83 0.017
immune effector process GO:0002252 321 0.017
respiratory system development GO:0060541 190 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.017
lipid localization GO:0010876 126 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
response to metal ion GO:0010038 47 0.017
positive regulation of neuron projection development GO:0010976 79 0.017
gtp catabolic process GO:0006184 143 0.017
cellular chemical homeostasis GO:0055082 215 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
protein maturation GO:0051604 176 0.017
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.016
protein processing GO:0016485 163 0.016
chondrocyte development GO:0002063 24 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
organelle localization GO:0051640 179 0.016
regulation of inflammatory response GO:0050727 147 0.016
cytokine production GO:0001816 319 0.016
regulation of defense response GO:0031347 233 0.016
organic acid transport GO:0015849 101 0.016
regulation of mapk cascade GO:0043408 248 0.016
cytoplasmic transport GO:0016482 234 0.016
intracellular protein transport GO:0006886 204 0.016
chromatin organization GO:0006325 206 0.015
circulatory system process GO:0003013 197 0.015
fibrinolysis GO:0042730 3 0.015
insulin processing GO:0030070 2 0.015
establishment of vesicle localization GO:0051650 81 0.015
innate immune response GO:0045087 157 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
polysaccharide metabolic process GO:0005976 39 0.015
trabecula morphogenesis GO:0061383 40 0.015
face development GO:0060324 38 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
positive regulation of defense response GO:0031349 124 0.015
endomembrane system organization GO:0010256 147 0.015
response to lipopolysaccharide GO:0032496 128 0.015
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.015
response to organic cyclic compound GO:0014070 198 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
regulation of biomineral tissue development GO:0070167 33 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
cell growth GO:0016049 130 0.015
positive regulation of neuron projection regeneration GO:0070572 2 0.015
regulation of vasculature development GO:1901342 88 0.015
transmembrane transport GO:0055085 412 0.015
positive regulation of cellular component biogenesis GO:0044089 94 0.014
recognition of apoptotic cell GO:0043654 3 0.014
inner ear morphogenesis GO:0042472 101 0.014
carbohydrate homeostasis GO:0033500 128 0.014
mapk cascade GO:0000165 281 0.014
negative regulation of cell motility GO:2000146 61 0.014
heterocycle catabolic process GO:0046700 280 0.014
oocyte axis specification GO:0007309 2 0.014
mesenchymal cell development GO:0014031 93 0.014
generation of precursor metabolites and energy GO:0006091 103 0.014
regulation of cellular component size GO:0032535 121 0.014
detection of molecule of bacterial origin GO:0032490 2 0.014
glucose homeostasis GO:0042593 128 0.014
synapse assembly GO:0007416 56 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
cerebral cortex development GO:0021987 86 0.014
carbohydrate metabolic process GO:0005975 230 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
negative regulation of dna replication GO:0008156 4 0.014
ear morphogenesis GO:0042471 118 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.013
muscle adaptation GO:0043500 39 0.013
stem cell differentiation GO:0048863 268 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
cardiac ventricle morphogenesis GO:0003208 50 0.013
bone mineralization GO:0030282 54 0.013
response to hypoxia GO:0001666 58 0.013
epithelial cell proliferation GO:0050673 174 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
learning or memory GO:0007611 148 0.013
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.013
myosin filament assembly GO:0031034 2 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
blood circulation GO:0008015 195 0.013
guanosine containing compound metabolic process GO:1901068 144 0.013
homeostasis of number of cells GO:0048872 210 0.013
covalent chromatin modification GO:0016569 163 0.013
cellular amine metabolic process GO:0044106 44 0.013
positive regulation of immune effector process GO:0002699 107 0.013
positive regulation of organelle organization GO:0010638 128 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
positive regulation of cell projection organization GO:0031346 95 0.013
rhythmic process GO:0048511 174 0.013
face morphogenesis GO:0060325 29 0.013
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.013
epithelial cell development GO:0002064 159 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
replacement ossification GO:0036075 26 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
cell junction assembly GO:0034329 52 0.013
phagocytosis GO:0006909 66 0.012
vesicle localization GO:0051648 86 0.012
negative regulation of ossification GO:0030279 49 0.012
regulation of actin cytoskeleton organization GO:0032956 84 0.012
proteoglycan metabolic process GO:0006029 38 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
regulation of blood circulation GO:1903522 93 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
negative regulation of lymphocyte activation GO:0051250 91 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
rac protein signal transduction GO:0016601 13 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
regulation of muscle adaptation GO:0043502 31 0.012
negative regulation of multi organism process GO:0043901 68 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
neuron projection guidance GO:0097485 141 0.012
metal ion homeostasis GO:0055065 189 0.012
protein heterotrimerization GO:0070208 8 0.012
wound healing spreading of cells GO:0044319 8 0.012
axon guidance GO:0007411 141 0.012
cellular lipid metabolic process GO:0044255 323 0.012
organic anion transport GO:0015711 137 0.012
membrane organization GO:0061024 245 0.012
dendritic spine maintenance GO:0097062 4 0.012
establishment of synaptic vesicle localization GO:0097480 57 0.011
mesenchyme development GO:0060485 152 0.011
multi multicellular organism process GO:0044706 109 0.011
placenta development GO:0001890 140 0.011
tissue remodeling GO:0048771 102 0.011
cell junction organization GO:0034330 77 0.011
cellular response to fluid shear stress GO:0071498 4 0.011
response to bmp GO:0071772 14 0.011
vascular process in circulatory system GO:0003018 62 0.011
germ cell development GO:0007281 185 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
actin cytoskeleton organization GO:0030036 220 0.011
exocytosis GO:0006887 121 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
regulation of map kinase activity GO:0043405 120 0.011
embryonic skeletal system development GO:0048706 120 0.011
response to insulin GO:0032868 100 0.011
regulation of neuron migration GO:2001222 22 0.011
positive regulation of phospholipase activity GO:0010518 3 0.011
carbohydrate biosynthetic process GO:0016051 74 0.011
multicellular organismal response to stress GO:0033555 62 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
sprouting angiogenesis GO:0002040 26 0.011
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.011
muscle tissue morphogenesis GO:0060415 53 0.011
cardiac chamber development GO:0003205 108 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
regulation of innate immune response GO:0045088 91 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
regulation of synapse assembly GO:0051963 29 0.011
erk1 and erk2 cascade GO:0070371 77 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
cell type specific apoptotic process GO:0097285 268 0.011
ventricular cardiac muscle tissue development GO:0003229 38 0.011
striated muscle cell development GO:0055002 125 0.011
negative regulation of cell activation GO:0050866 111 0.011
cognition GO:0050890 149 0.011
limb development GO:0060173 166 0.011
negative regulation of cell migration GO:0030336 59 0.011
regulation of hormone secretion GO:0046883 88 0.011
fibril organization GO:0097435 2 0.011
circadian temperature homeostasis GO:0060086 2 0.011
regulation of ion transport GO:0043269 215 0.011
peptide transport GO:0015833 133 0.011
negative regulation of interleukin 10 secretion GO:2001180 2 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.010
ribonucleoside triphosphate catabolic process GO:0009203 199 0.010
gtp metabolic process GO:0046039 144 0.010
nucleotide sugar metabolic process GO:0009225 4 0.010
regulation of hydrolase activity GO:0051336 246 0.010
foramen ovale closure GO:0035922 1 0.010
macromolecule catabolic process GO:0009057 281 0.010
leukocyte differentiation GO:0002521 342 0.010
regulation of kinase activity GO:0043549 249 0.010
oocyte construction GO:0007308 2 0.010
renal system development GO:0072001 225 0.010
negative regulation of molecular function GO:0044092 258 0.010
spermatid differentiation GO:0048515 115 0.010
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010
cellular response to insulin stimulus GO:0032869 78 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
sulfur compound metabolic process GO:0006790 100 0.010
lung development GO:0030324 164 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.010
peptide secretion GO:0002790 114 0.010
mitochondrion organization GO:0007005 134 0.010
positive regulation of proteolysis GO:0045862 85 0.010
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
protein secretion GO:0009306 111 0.010
nucleoside metabolic process GO:0009116 246 0.010
purine ribonucleoside catabolic process GO:0046130 205 0.010

Emilin1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.534
connective tissue disease DOID:65 0 0.534
musculoskeletal system disease DOID:17 0 0.534
bone disease DOID:0080001 0 0.148
bone development disease DOID:0080006 0 0.148
osteochondrodysplasia DOID:2256 0 0.123
osteogenesis imperfecta DOID:12347 0 0.067
muscular disease DOID:0080000 0 0.023
muscle tissue disease DOID:66 0 0.023
disease of cellular proliferation DOID:14566 0 0.016
bone remodeling disease DOID:0080005 0 0.013
nervous system disease DOID:863 0 0.012