Mus musculus

117 known processes

En1

engrailed 1

(Aliases: Mo-en.1,En-1)

En1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
midbrain hindbrain boundary development GO:0030917 9 0.999
bmp signaling pathway GO:0030509 93 0.999
hindbrain development GO:0030902 128 0.998
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.998
regulation of bmp signaling pathway GO:0030510 60 0.998
cerebellum development GO:0021549 77 0.998
metencephalon development GO:0022037 89 0.997
cerebellum morphogenesis GO:0021587 42 0.997
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.997
anterior commissure morphogenesis GO:0021960 6 0.997
Fly
rostrocaudal neural tube patterning GO:0021903 12 0.996
auditory receptor cell fate determination GO:0042668 3 0.996
regionalization GO:0003002 337 0.996
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.996
embryonic appendage morphogenesis GO:0035113 126 0.995
hindbrain morphogenesis GO:0021575 46 0.993
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.992
skeletal system morphogenesis GO:0048705 203 0.989
neuron fate specification GO:0048665 30 0.987
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.986
appendage morphogenesis GO:0035107 149 0.985
midbrain development GO:0030901 35 0.984
embryonic organ morphogenesis GO:0048562 276 0.984
brain segmentation GO:0035284 3 0.983
chondrocyte differentiation GO:0002062 72 0.983
axon guidance GO:0007411 141 0.982
Fly
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.981
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.981
limb development GO:0060173 166 0.980
neuron projection guidance GO:0097485 141 0.980
Fly
central nervous system neuron differentiation GO:0021953 162 0.979
Fly
peripheral nervous system neuron axonogenesis GO:0048936 3 0.978
ventral midline development GO:0007418 4 0.977
Fly
neural tube closure GO:0001843 90 0.977
motor neuron migration GO:0097475 4 0.975
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.975
cartilage development GO:0051216 140 0.975
cerebellar cortex development GO:0021695 48 0.972
cell proliferation in hindbrain GO:0021534 10 0.970
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.966
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.962
ectoderm formation GO:0001705 3 0.962
positive regulation of programmed cell death GO:0043068 218 0.955
gland development GO:0048732 330 0.955
spinal cord motor neuron migration GO:0097476 4 0.953
lateral motor column neuron migration GO:0097477 3 0.953
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.951
paraxial mesodermal cell differentiation GO:0048342 2 0.951
positive regulation of cartilage development GO:0061036 18 0.950
cell differentiation in hindbrain GO:0021533 24 0.950
positive regulation of apoptotic process GO:0043065 217 0.949
epithelial cell morphogenesis GO:0003382 41 0.946
epithelial tube morphogenesis GO:0060562 303 0.946
endocrine system development GO:0035270 98 0.944
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.941
diencephalon development GO:0021536 63 0.939
spinal cord development GO:0021510 81 0.938
pituitary gland development GO:0021983 38 0.937
heart morphogenesis GO:0003007 178 0.936
bone morphogenesis GO:0060349 78 0.935
axis elongation involved in somitogenesis GO:0090245 4 0.932
central nervous system neuron development GO:0021954 67 0.932
Fly
neural tube development GO:0021915 160 0.932
forelimb morphogenesis GO:0035136 40 0.929
positive regulation of rhodopsin gene expression GO:0045872 2 0.929
spinal cord association neuron differentiation GO:0021527 14 0.928
cell proliferation in forebrain GO:0021846 30 0.926
negative regulation of bmp signaling pathway GO:0030514 35 0.923
paraxial mesodermal cell fate commitment GO:0048343 2 0.922
locomotory behavior GO:0007626 195 0.921
positive regulation of bmp signaling pathway GO:0030513 23 0.920
stem cell differentiation GO:0048863 268 0.918
Fly
regulation of binding GO:0051098 111 0.918
astrocyte differentiation GO:0048708 43 0.917
embryonic heart tube morphogenesis GO:0003143 51 0.917
neural tube formation GO:0001841 108 0.916
gastrulation GO:0007369 116 0.916
olfactory lobe development GO:0021988 32 0.914
hemangioblast cell differentiation GO:0060217 1 0.914
pyramidal neuron migration GO:0021852 1 0.910
regulation of organ morphogenesis GO:2000027 144 0.909
ureteric bud morphogenesis GO:0060675 62 0.905
glial cell differentiation GO:0010001 131 0.905
pancreatic a cell fate commitment GO:0003326 2 0.903
cell fate commitment GO:0045165 210 0.902
Zebrafish Worm Fly
central nervous system segmentation GO:0035283 3 0.902
morphogenesis of embryonic epithelium GO:0016331 159 0.901
neural tube patterning GO:0021532 43 0.900
renal tubule development GO:0061326 87 0.899
positive regulation of cell death GO:0010942 224 0.896
pancreatic pp cell fate commitment GO:0003329 2 0.895
cerebellar cortex formation GO:0021697 22 0.890
myotube differentiation GO:0014902 105 0.890
neuron death GO:0070997 154 0.890
regulation of cartilage development GO:0061035 44 0.890
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.890
spinal cord motor neuron cell fate specification GO:0021520 13 0.889
primitive streak formation GO:0090009 10 0.888
striated muscle tissue development GO:0014706 293 0.888
somitogenesis GO:0001756 69 0.887
bone development GO:0060348 120 0.885
cerebellar cortex morphogenesis GO:0021696 32 0.885
sensory organ morphogenesis GO:0090596 242 0.883
appendage development GO:0048736 166 0.880
cerebral cortex radially oriented cell migration GO:0021799 31 0.879
neuron fate determination GO:0048664 9 0.878
apoptotic process involved in morphogenesis GO:0060561 25 0.875
neural crest cell differentiation GO:0014033 54 0.874
embryonic retina morphogenesis in camera type eye GO:0060059 7 0.873
sclerotome development GO:0061056 4 0.872
dentate gyrus development GO:0021542 14 0.871
auditory receptor cell fate specification GO:0042667 1 0.867
fourth ventricle development GO:0021592 2 0.867
axonogenesis GO:0007409 274 0.863
Fly
visceral motor neuron differentiation GO:0021524 3 0.861
peripheral nervous system neuron development GO:0048935 9 0.861
gonad morphogenesis GO:0035262 1 0.860
regulation of neuron projection development GO:0010975 169 0.860
connective tissue development GO:0061448 179 0.858
pallium development GO:0021543 120 0.854
thalamus development GO:0021794 11 0.854
negative regulation of cellular amine metabolic process GO:0033239 1 0.851
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.851
digestive tract development GO:0048565 190 0.850
ureteric bud development GO:0001657 94 0.850
metanephros morphogenesis GO:0003338 24 0.849
tendon formation GO:0035992 4 0.849
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.849
cell fate specification GO:0001708 72 0.848
Worm
cell fate determination GO:0001709 32 0.847
Fly
somite development GO:0061053 81 0.845
cerebellar granule cell precursor proliferation GO:0021930 10 0.845
nephron tubule morphogenesis GO:0072078 68 0.844
formation of primary germ layer GO:0001704 77 0.841
cartilage morphogenesis GO:0060536 11 0.841
kidney morphogenesis GO:0060993 83 0.839
regulation of establishment of planar polarity GO:0090175 28 0.839
olfactory bulb development GO:0021772 30 0.839
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.838
nephron morphogenesis GO:0072028 69 0.837
inner ear receptor cell differentiation GO:0060113 61 0.836
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.835
regulation of neuron differentiation GO:0045664 281 0.835
embryonic heart tube formation GO:0003144 1 0.833
telencephalon development GO:0021537 186 0.833
Fly
branching morphogenesis of an epithelial tube GO:0048754 159 0.832
mesonephros development GO:0001823 97 0.831
positive regulation of epithelial cell differentiation involved in kidney development GO:2000698 2 0.831
ventricular septum development GO:0003281 42 0.830
cerebellum formation GO:0021588 1 0.828
neuroblast differentiation GO:0014016 2 0.826
Fly
mesoderm development GO:0007498 100 0.820
autonomic nervous system development GO:0048483 43 0.820
digestive tract morphogenesis GO:0048546 147 0.820
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.818
dorsal spinal cord development GO:0021516 20 0.812
kidney epithelium development GO:0072073 121 0.809
endochondral bone morphogenesis GO:0060350 50 0.807
primary neural tube formation GO:0014020 95 0.807
positive regulation of binding GO:0051099 49 0.806
mesenchyme morphogenesis GO:0072132 32 0.806
embryonic skeletal system development GO:0048706 120 0.802
motor neuron axon guidance GO:0008045 26 0.801
outflow tract morphogenesis GO:0003151 53 0.799
retinal ganglion cell axon guidance GO:0031290 18 0.793
regulation of rhodopsin gene expression GO:0007468 3 0.790
epidermis development GO:0008544 187 0.790
Worm
segmentation GO:0035282 93 0.786
regulation of chondrocyte differentiation GO:0032330 33 0.785
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.784
positive regulation of macrophage colony stimulating factor production GO:1901258 1 0.781
cellular response to growth factor stimulus GO:0071363 197 0.781
regulation of organelle organization GO:0033043 289 0.778
skeletal system development GO:0001501 356 0.773
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.772
forebrain regionalization GO:0021871 25 0.770
cardiac right atrium morphogenesis GO:0003213 3 0.767
hypophysis morphogenesis GO:0048850 3 0.767
morphogenesis of a branching epithelium GO:0061138 193 0.764
mesenchymal cell development GO:0014031 93 0.763
nephron epithelium morphogenesis GO:0072088 68 0.763
skeletal muscle fiber development GO:0048741 58 0.763
hindbrain formation GO:0021576 1 0.762
oviduct development GO:0060066 3 0.761
neural plate morphogenesis GO:0001839 9 0.761
cell type specific apoptotic process GO:0097285 268 0.759
embryonic skeletal system morphogenesis GO:0048704 91 0.758
endodermal cell fate specification GO:0001714 4 0.757
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.756
negative regulation of synapse maturation GO:2000297 2 0.756
forebrain neuron differentiation GO:0021879 52 0.755
hippocampus development GO:0021766 52 0.754
pancreatic pp cell differentiation GO:0003312 2 0.753
stem cell fate determination GO:0048867 2 0.753
Fly
odontogenesis of dentin containing tooth GO:0042475 66 0.752
metanephric nephron morphogenesis GO:0072273 19 0.752
neural crest cell development GO:0014032 48 0.748
cardiac epithelial to mesenchymal transition GO:0060317 18 0.745
protein ubiquitination GO:0016567 171 0.745
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.737
neuroblast fate determination GO:0007400 1 0.736
Fly
regulation of mast cell differentiation GO:0060375 3 0.735
ventral spinal cord interneuron differentiation GO:0021514 16 0.734
positive regulation of transcription by glucose GO:0046016 3 0.731
embryonic heart tube development GO:0035050 65 0.731
forebrain neuron development GO:0021884 30 0.730
nephron tubule development GO:0072080 84 0.730
positive regulation of mitotic cell cycle GO:0045931 41 0.729
heart formation GO:0060914 16 0.727
metanephric loop of henle development GO:0072236 4 0.726
adult behavior GO:0030534 135 0.725
dorsal ventral neural tube patterning GO:0021904 28 0.725
mesonephric duct morphogenesis GO:0072180 4 0.723
positive regulation of skeletal muscle fiber development GO:0048743 3 0.723
peptidyl amino acid modification GO:0018193 336 0.721
positive regulation of neuron differentiation GO:0045666 141 0.720
regulation of embryonic development GO:0045995 71 0.716
regulation of cytokine production GO:0001817 266 0.713
paramesonephric duct development GO:0061205 3 0.708
neuron apoptotic process GO:0051402 142 0.707
embryonic hindlimb morphogenesis GO:0035116 32 0.707
regulation of neuron apoptotic process GO:0043523 122 0.701
regulation of auditory receptor cell differentiation GO:0045607 4 0.700
renal tubule morphogenesis GO:0061333 72 0.698
regulation of organ formation GO:0003156 34 0.694
cell proliferation involved in heart valve development GO:2000793 2 0.694
renal system development GO:0072001 225 0.691
skeletal muscle cell differentiation GO:0035914 66 0.691
camera type eye development GO:0043010 266 0.688
hindlimb morphogenesis GO:0035137 42 0.686
regulation of cellular amine metabolic process GO:0033238 20 0.685
nephric duct elongation GO:0035849 1 0.684
aortic valve morphogenesis GO:0003180 4 0.684
regulation of epidermal cell differentiation GO:0045604 21 0.681
morphogenesis of a polarized epithelium GO:0001738 37 0.678
spinal cord motor neuron differentiation GO:0021522 35 0.676
neuroblast proliferation GO:0007405 49 0.670
mesenchymal cell differentiation GO:0048762 107 0.669
horizontal cell localization GO:0035852 1 0.667
regulation of cell cycle GO:0051726 281 0.667
dendrite development GO:0016358 115 0.665
regulation of cellular amino acid metabolic process GO:0006521 5 0.661
developmental growth involved in morphogenesis GO:0060560 138 0.660
cardiac right ventricle formation GO:0003219 3 0.659
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.658
muscle cell differentiation GO:0042692 261 0.657
deltoid tuberosity development GO:0035993 3 0.656
regulation of epidermis development GO:0045682 33 0.656
learning GO:0007612 98 0.656
positive regulation of nephron tubule epithelial cell differentiation GO:2000768 1 0.654
ventral spinal cord interneuron specification GO:0021521 11 0.654
gliogenesis GO:0042063 141 0.653
synaptic transmission GO:0007268 329 0.653
cerebellar purkinje cell layer development GO:0021680 26 0.653
somatotropin secreting cell differentiation GO:0060126 4 0.650
extracellular structure organization GO:0043062 148 0.650
mitral valve morphogenesis GO:0003183 4 0.649
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.649
cardiac ventricle morphogenesis GO:0003208 50 0.649
epithelial cell development GO:0002064 159 0.648
embryonic viscerocranium morphogenesis GO:0048703 8 0.647
nuclear division GO:0000280 158 0.647
branching involved in ureteric bud morphogenesis GO:0001658 56 0.647
trachea cartilage morphogenesis GO:0060535 4 0.645
epidermal cell fate specification GO:0009957 1 0.644
Worm
forebrain development GO:0030900 302 0.642
Fly
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.640
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.635
tube formation GO:0035148 140 0.634
stem cell proliferation GO:0072089 117 0.633
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.632
forebrain morphogenesis GO:0048853 17 0.632
muscle tissue development GO:0060537 308 0.632
odontogenesis GO:0042476 78 0.631
kidney development GO:0001822 213 0.631
somatic sex determination GO:0018993 2 0.630
muscle cell fate specification GO:0042694 1 0.630
limbic system development GO:0021761 72 0.625
cerebellar granule cell differentiation GO:0021707 9 0.625
central nervous system projection neuron axonogenesis GO:0021952 21 0.622
Fly
cardiac septum development GO:0003279 59 0.622
adult locomotory behavior GO:0008344 91 0.622
ear development GO:0043583 200 0.621
cell proliferation involved in heart morphogenesis GO:0061323 15 0.620
extracellular matrix organization GO:0030198 147 0.617
forebrain cell migration GO:0021885 58 0.615
cellular amino acid metabolic process GO:0006520 103 0.614
midbrain hindbrain boundary maturation GO:0021732 1 0.613
brain morphogenesis GO:0048854 32 0.612
nephron tubule formation GO:0072079 20 0.612
determination of heart left right asymmetry GO:0061371 48 0.610
lung induction GO:0060492 3 0.610
nerve development GO:0021675 67 0.609
ventral spinal cord interneuron fate commitment GO:0060579 14 0.608
glial cell fate commitment GO:0021781 14 0.608
uterus morphogenesis GO:0061038 2 0.607
granulocyte colony stimulating factor production GO:0071611 1 0.606
neuromuscular process GO:0050905 99 0.605
cardiac muscle tissue development GO:0048738 130 0.604
negative regulation of cell cycle GO:0045786 123 0.601
loop of henle development GO:0072070 10 0.600
embryonic limb morphogenesis GO:0030326 126 0.600
cardiocyte differentiation GO:0035051 87 0.599
regulation of secretion by cell GO:1903530 249 0.598
rhythmic process GO:0048511 174 0.598
organelle fission GO:0048285 170 0.597
negative regulation of nervous system development GO:0051961 156 0.595
cell proliferation in external granule layer GO:0021924 10 0.594
forebrain radial glial cell differentiation GO:0021861 4 0.593
cellular amine metabolic process GO:0044106 44 0.593
cell differentiation in spinal cord GO:0021515 53 0.593
endocrine pancreas development GO:0031018 29 0.591
medial motor column neuron differentiation GO:0021526 2 0.591
positive regulation of keratinocyte proliferation GO:0010838 4 0.589
cell fate specification involved in pattern specification GO:0060573 11 0.587
cerebral cortex development GO:0021987 86 0.585
stem cell maintenance GO:0019827 130 0.585
stem cell development GO:0048864 219 0.584
cardiac ventricle development GO:0003231 83 0.583
protein modification by small protein conjugation GO:0032446 187 0.581
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.580
epithelial to mesenchymal transition GO:0001837 47 0.577
transdifferentiation GO:0060290 1 0.577
chondrocyte development GO:0002063 24 0.577
regulation of gastrulation GO:0010470 16 0.576
regulation of axon diameter GO:0031133 6 0.576
mesenchyme development GO:0060485 152 0.573
pancreas development GO:0031016 57 0.572
endocardial cushion morphogenesis GO:0003203 18 0.571
regulation of heart morphogenesis GO:2000826 22 0.571
regulation of retina development in camera type eye GO:1902866 3 0.564
astrocyte fate commitment GO:0060018 4 0.562
trophectodermal cell differentiation GO:0001829 21 0.561
apoptotic process involved in development GO:1902742 28 0.561
regulation of neural retina development GO:0061074 3 0.559
photoreceptor cell fate commitment GO:0046552 2 0.557
positive regulation of nervous system development GO:0051962 221 0.546
regulation of vascular wound healing GO:0061043 2 0.546
embryonic digit morphogenesis GO:0042733 56 0.544
developmental cell growth GO:0048588 84 0.543
mechanoreceptor differentiation GO:0042490 67 0.542
tendon cell differentiation GO:0035990 4 0.539
trabecular meshwork development GO:0002930 2 0.539
cerebellar granular layer development GO:0021681 13 0.538
determination of left right symmetry GO:0007368 80 0.536
pericardium development GO:0060039 16 0.534
cardiac chamber morphogenesis GO:0003206 93 0.533
positive regulation of cell cycle GO:0045787 92 0.531
regulation of muscle tissue development GO:1901861 97 0.529
neural retina development GO:0003407 41 0.529
protein processing GO:0016485 163 0.529
neuroendocrine cell differentiation GO:0061101 7 0.528
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.527
cardiac muscle tissue morphogenesis GO:0055008 44 0.527
neuron projection extension GO:1990138 64 0.526
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.524
hair cell differentiation GO:0035315 40 0.521
spemann organizer formation GO:0060061 2 0.520
cardiac septum morphogenesis GO:0060411 46 0.518
defense response to fungus GO:0050832 12 0.514
Fly
cellular ketone metabolic process GO:0042180 84 0.512
mesonephric duct formation GO:0072181 2 0.511
t cell proliferation GO:0042098 120 0.509
regulation of fat cell differentiation GO:0045598 81 0.509
cranial suture morphogenesis GO:0060363 8 0.509
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.508
ventral spinal cord development GO:0021517 48 0.507
negative regulation of molecular function GO:0044092 258 0.502
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.500
corticotropin hormone secreting cell differentiation GO:0060128 3 0.499
negative regulation of neuron death GO:1901215 98 0.499
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.498
positive regulation of cardiac muscle tissue development GO:0055025 19 0.498
extraocular skeletal muscle development GO:0002074 2 0.497
forebrain generation of neurons GO:0021872 63 0.495
regulation of wnt signaling pathway GO:0030111 123 0.494
pattern specification involved in metanephros development GO:0072268 4 0.494
chemotaxis GO:0006935 247 0.493
Fly
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.493
mesonephric tubule development GO:0072164 94 0.490
skeletal muscle organ development GO:0060538 163 0.489
nephron epithelium development GO:0072009 92 0.488
forebrain anterior posterior pattern specification GO:0021797 5 0.487
positive regulation of organelle organization GO:0010638 128 0.485
neural crest cell migration GO:0001755 32 0.484
regulation of neural precursor cell proliferation GO:2000177 70 0.480
gonad development GO:0008406 141 0.480
Fly
cerebral cortex neuron differentiation GO:0021895 19 0.479
metanephric s shaped body morphogenesis GO:0072284 2 0.479
cardiac chamber development GO:0003205 108 0.471
negative regulation of dna binding GO:0043392 20 0.470
developmental programmed cell death GO:0010623 41 0.468
telencephalon regionalization GO:0021978 14 0.464
interneuron migration from the subpallium to the cortex GO:0021830 7 0.462
cell maturation GO:0048469 127 0.461
cerebellar purkinje cell granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation GO:0021937 6 0.459
regulation of cerebellar granule cell precursor proliferation GO:0021936 12 0.456
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.456
epithelial tube formation GO:0072175 130 0.456
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.456
muscle cell development GO:0055001 133 0.454
rhombomere morphogenesis GO:0021593 2 0.454
regulation of interleukin 1 alpha production GO:0032650 4 0.452
regulation of interleukin 1 production GO:0032652 26 0.451
telencephalon cell migration GO:0022029 55 0.450
maintenance of apical basal cell polarity GO:0035090 3 0.449
urogenital system development GO:0001655 261 0.448
myoblast differentiation GO:0045445 52 0.446
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.445
organ growth GO:0035265 117 0.444
negative regulation of protein metabolic process GO:0051248 282 0.444
central nervous system neuron axonogenesis GO:0021955 28 0.440
Fly
adenohypophysis development GO:0021984 14 0.439
visceral serous pericardium development GO:0061032 2 0.439
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.439
nephric duct formation GO:0072179 4 0.438
learning or memory GO:0007611 148 0.438
mesenchymal to epithelial transition GO:0060231 12 0.437
cell division GO:0051301 120 0.437
rhombomere 2 development GO:0021568 2 0.435
epithelial mesenchymal signaling involved in prostate gland development GO:0060738 2 0.435
amine metabolic process GO:0009308 45 0.434
carbon catabolite activation of transcription GO:0045991 4 0.434
forebrain neuron fate commitment GO:0021877 13 0.433
compartment pattern specification GO:0007386 4 0.431
Fly
positive regulation of smoothened signaling pathway GO:0045880 23 0.430
circadian rhythm GO:0007623 114 0.429
eye photoreceptor cell fate commitment GO:0042706 2 0.427
epithelial cell fate commitment GO:0072148 13 0.425
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.423
negative regulation of cell aging GO:0090344 5 0.421
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.421
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.420
regulation of mapk cascade GO:0043408 248 0.420
inner ear morphogenesis GO:0042472 101 0.419
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.418
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.418
olfactory bulb interneuron development GO:0021891 7 0.417
defecation GO:0030421 1 0.416
neural precursor cell proliferation GO:0061351 121 0.415
blastocyst formation GO:0001825 33 0.415
mesenchymal cell proliferation GO:0010463 44 0.415
rhombomere 5 development GO:0021571 4 0.414
compound eye development GO:0048749 1 0.413
negative regulation of neuron differentiation GO:0045665 101 0.413
muscle tissue morphogenesis GO:0060415 53 0.411
cardiac atrium morphogenesis GO:0003209 23 0.411
limb morphogenesis GO:0035108 149 0.411
metanephric dct cell differentiation GO:0072240 3 0.411
metanephros development GO:0001656 79 0.409
muscle cell fate commitment GO:0042693 11 0.408
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.408
regulation of osteoblast differentiation GO:0045667 67 0.408
ear morphogenesis GO:0042471 118 0.408
development of primary sexual characteristics GO:0045137 143 0.408
Fly
eye photoreceptor cell differentiation GO:0001754 41 0.406
regulation of interleukin 2 secretion GO:1900040 6 0.406
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.406
amacrine cell differentiation GO:0035881 5 0.405
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.404
regulation of smoothened signaling pathway GO:0008589 58 0.404
cardiac neural crest cell development involved in outflow tract morphogenesis GO:0061309 6 0.403
neuron migration GO:0001764 122 0.403
negative regulation of cellular component organization GO:0051129 194 0.403
dorsal ventral axon guidance GO:0033563 3 0.401
positive regulation of protein transport GO:0051222 93 0.401
neural plate development GO:0001840 12 0.401
embryonic placenta development GO:0001892 98 0.400
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.400
dopaminergic neuron differentiation GO:0071542 14 0.400
regulation of mechanoreceptor differentiation GO:0045631 5 0.399
central nervous system morphogenesis GO:0021551 2 0.399
ossification GO:0001503 216 0.398
female gonad development GO:0008585 71 0.398
endocardial cushion to mesenchymal transition GO:0090500 5 0.398
cardiac neural crest cell differentiation involved in heart development GO:0061307 8 0.397
cardiac neural crest cell development involved in heart development GO:0061308 7 0.395
regulation of cell proliferation involved in heart morphogenesis GO:2000136 15 0.395
negative regulation of prostatic bud formation GO:0060686 4 0.394
spermatogenesis GO:0007283 284 0.394
retina morphogenesis in camera type eye GO:0060042 45 0.390
mesodermal cell differentiation GO:0048333 22 0.390
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.386
endodermal cell fate commitment GO:0001711 12 0.386
non canonical wnt signaling pathway GO:0035567 33 0.383
tube closure GO:0060606 91 0.383
mesonephric tubule morphogenesis GO:0072171 63 0.380
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.378
cytokine production GO:0001816 319 0.375
atrial cardiac muscle tissue development GO:0003228 5 0.373
cardiac muscle cell differentiation GO:0055007 69 0.372
rhombomere development GO:0021546 8 0.372
metanephric renal vesicle morphogenesis GO:0072283 12 0.371
face development GO:0060324 38 0.371
somite rostral caudal axis specification GO:0032525 13 0.371
sensory neuron axon guidance GO:0097374 3 0.370

En1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.404
musculoskeletal system disease DOID:17 0 0.404
connective tissue disease DOID:65 0 0.404