Mus musculus

125 known processes

Entpd5

ectonucleoside triphosphate diphosphohydrolase 5

(Aliases: NTPDase5,ER-UDPase,NTPDase-5,AI196558,mNTPase,Pcph,Cd39l4,AI987697)

Entpd5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular lipid metabolic process GO:0044255 323 0.491
oxidation reduction process GO:0055114 342 0.485
fatty acid metabolic process GO:0006631 121 0.337
acetate metabolic process GO:0006083 1 0.208
coenzyme metabolic process GO:0006732 52 0.198
lipid oxidation GO:0034440 29 0.173
sulfur compound metabolic process GO:0006790 100 0.165
thioester metabolic process GO:0035383 19 0.143
monocarboxylic acid metabolic process GO:0032787 191 0.132
carnitine metabolic process GO:0009437 7 0.125
fatty acid oxidation GO:0019395 28 0.121
ribonucleoside bisphosphate metabolic process GO:0033875 9 0.111
organic hydroxy compound metabolic process GO:1901615 203 0.105
cofactor metabolic process GO:0051186 80 0.103
nucleoside phosphate metabolic process GO:0006753 338 0.102
cellular ketone metabolic process GO:0042180 84 0.095
cellular amino acid metabolic process GO:0006520 103 0.090
nucleotide metabolic process GO:0009117 332 0.085
organic acid catabolic process GO:0016054 51 0.082
transmembrane transport GO:0055085 412 0.081
small molecule biosynthetic process GO:0044283 132 0.081
lipid biosynthetic process GO:0008610 179 0.079
cellular amine metabolic process GO:0044106 44 0.067
nucleobase containing small molecule metabolic process GO:0055086 352 0.066
carboxylic acid catabolic process GO:0046395 51 0.066
small molecule catabolic process GO:0044282 71 0.065
coenzyme biosynthetic process GO:0009108 23 0.064
mitochondrion organization GO:0007005 134 0.062
regulation of cellular ketone metabolic process GO:0010565 66 0.061
purine ribonucleotide metabolic process GO:0009150 290 0.061
organic anion transport GO:0015711 137 0.060
thioester biosynthetic process GO:0035384 7 0.056
ribonucleoside metabolic process GO:0009119 245 0.054
carboxylic acid biosynthetic process GO:0046394 86 0.052
acyl coa metabolic process GO:0006637 19 0.050
ion transmembrane transport GO:0034220 361 0.047
amine metabolic process GO:0009308 45 0.046
anion transport GO:0006820 177 0.045
protein oligomerization GO:0051259 67 0.044
cellular lipid catabolic process GO:0044242 52 0.042
purine nucleotide metabolic process GO:0006163 302 0.042
organonitrogen compound catabolic process GO:1901565 264 0.042
very long chain fatty acid metabolic process GO:0000038 8 0.041
organic acid biosynthetic process GO:0016053 86 0.039
alcohol metabolic process GO:0006066 116 0.039
xenobiotic catabolic process GO:0042178 1 0.038
purine nucleoside metabolic process GO:0042278 241 0.038
ribonucleotide metabolic process GO:0009259 291 0.037
establishment of protein localization to peroxisome GO:0072663 4 0.037
cellular modified amino acid metabolic process GO:0006575 63 0.037
coenzyme a metabolic process GO:0015936 8 0.037
glycerolipid metabolic process GO:0046486 122 0.037
amino acid betaine metabolic process GO:0006577 7 0.036
acylglycerol metabolic process GO:0006639 55 0.035
striated muscle tissue development GO:0014706 293 0.034
response to organonitrogen compound GO:0010243 246 0.034
muscle tissue development GO:0060537 308 0.033
cation transmembrane transport GO:0098655 266 0.033
organic acid transport GO:0015849 101 0.033
response to nutrient levels GO:0031667 109 0.032
organonitrogen compound biosynthetic process GO:1901566 192 0.032
response to oxidative stress GO:0006979 123 0.032
purine ribonucleoside metabolic process GO:0046128 241 0.032
glutathione metabolic process GO:0006749 16 0.031
carboxylic acid transport GO:0046942 100 0.031
energy derivation by oxidation of organic compounds GO:0015980 77 0.030
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
muscle cell differentiation GO:0042692 261 0.030
nucleoside metabolic process GO:0009116 246 0.029
monocarboxylic acid catabolic process GO:0072329 27 0.029
neutral lipid metabolic process GO:0006638 57 0.028
monocarboxylic acid biosynthetic process GO:0072330 61 0.028
organic cyclic compound catabolic process GO:1901361 295 0.027
sulfur compound biosynthetic process GO:0044272 37 0.027
terpenoid metabolic process GO:0006721 25 0.027
response to organic cyclic compound GO:0014070 198 0.027
cellular amino acid catabolic process GO:0009063 25 0.027
lipid catabolic process GO:0016042 69 0.027
cofactor biosynthetic process GO:0051188 41 0.027
peptide metabolic process GO:0006518 46 0.027
very long chain fatty acid catabolic process GO:0042760 2 0.027
cellular homeostasis GO:0019725 240 0.026
cation transport GO:0006812 399 0.026
forebrain development GO:0030900 302 0.026
hexose biosynthetic process GO:0019319 39 0.026
protein localization to peroxisome GO:0072662 4 0.025
coenzyme catabolic process GO:0009109 5 0.025
cation homeostasis GO:0055080 212 0.025
fatty acid beta oxidation GO:0006635 16 0.025
regulation of membrane potential GO:0042391 192 0.025
response to extracellular stimulus GO:0009991 127 0.025
male gamete generation GO:0048232 285 0.025
regulation of transferase activity GO:0051338 263 0.025
multicellular organismal homeostasis GO:0048871 164 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.024
amp metabolic process GO:0046033 4 0.024
cellular amide metabolic process GO:0043603 58 0.024
lipid modification GO:0030258 65 0.024
regulation of hormone levels GO:0010817 211 0.024
response to testosterone GO:0033574 3 0.024
glucose metabolic process GO:0006006 92 0.024
regulation of organelle organization GO:0033043 289 0.024
maintenance of location GO:0051235 89 0.024
acetyl coa biosynthetic process GO:0006085 5 0.024
monosaccharide metabolic process GO:0005996 106 0.024
cofactor transport GO:0051181 4 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
skin development GO:0043588 220 0.023
regulation of cellular amine metabolic process GO:0033238 20 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
branched chain amino acid catabolic process GO:0009083 2 0.023
protein maturation GO:0051604 176 0.023
carbohydrate metabolic process GO:0005975 230 0.023
anion transmembrane transport GO:0098656 71 0.022
skeletal system development GO:0001501 356 0.022
dephosphorylation GO:0016311 129 0.022
generation of precursor metabolites and energy GO:0006091 103 0.022
germ cell development GO:0007281 185 0.022
liver development GO:0001889 66 0.022
endomembrane system organization GO:0010256 147 0.021
cellular alcohol metabolic process GO:0044107 3 0.021
spermatogenesis GO:0007283 284 0.021
cellular carbohydrate metabolic process GO:0044262 119 0.021
telencephalon development GO:0021537 186 0.021
cardiac muscle tissue development GO:0048738 130 0.021
purine containing compound metabolic process GO:0072521 311 0.021
cytokine production GO:0001816 319 0.021
nucleoside bisphosphate metabolic process GO:0033865 9 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
sensory organ morphogenesis GO:0090596 242 0.021
fat cell differentiation GO:0045444 160 0.021
homeostasis of number of cells GO:0048872 210 0.020
hormone metabolic process GO:0042445 86 0.020
glycosyl compound metabolic process GO:1901657 246 0.020
g protein coupled receptor signaling pathway GO:0007186 243 0.020
heterocycle catabolic process GO:0046700 280 0.020
spermatid differentiation GO:0048515 115 0.020
establishment of protein localization to organelle GO:0072594 118 0.020
intracellular protein transport GO:0006886 204 0.020
diterpenoid metabolic process GO:0016101 24 0.020
sensory perception GO:0007600 245 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
lung development GO:0030324 164 0.020
negative regulation of cellular amine metabolic process GO:0033239 1 0.020
reactive nitrogen species metabolic process GO:2001057 0 0.019
respiratory tube development GO:0030323 167 0.019
membrane organization GO:0061024 245 0.019
nucleotide biosynthetic process GO:0009165 78 0.019
hexose metabolic process GO:0019318 98 0.019
regulation of cytokine production GO:0001817 266 0.019
respiratory system development GO:0060541 190 0.019
carbohydrate biosynthetic process GO:0016051 74 0.019
peptidyl amino acid modification GO:0018193 336 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
locomotory behavior GO:0007626 195 0.019
regulation of homeostatic process GO:0032844 182 0.019
positive regulation of protein modification process GO:0031401 299 0.019
leukocyte differentiation GO:0002521 342 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.018
protein targeting to peroxisome GO:0006625 4 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
regulation of kinase activity GO:0043549 249 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
isoprenoid metabolic process GO:0006720 29 0.018
purine containing compound biosynthetic process GO:0072522 70 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
steroid metabolic process GO:0008202 119 0.018
regulation of protein kinase activity GO:0045859 232 0.018
hepaticobiliary system development GO:0061008 67 0.018
organophosphate catabolic process GO:0046434 232 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.017
mapk cascade GO:0000165 281 0.017
cytoplasmic transport GO:0016482 234 0.017
macromolecule catabolic process GO:0009057 281 0.017
divalent metal ion transport GO:0070838 172 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
response to inorganic substance GO:0010035 96 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
positive regulation of cell death GO:0010942 224 0.017
cellular metal ion homeostasis GO:0006875 151 0.017
ossification GO:0001503 216 0.017
lipid localization GO:0010876 126 0.017
apoptotic signaling pathway GO:0097190 306 0.017
gland development GO:0048732 330 0.017
nitrogen compound transport GO:0071705 271 0.017
inorganic ion transmembrane transport GO:0098660 234 0.017
microtubule based process GO:0007017 236 0.017
fatty acid catabolic process GO:0009062 25 0.016
fatty acid biosynthetic process GO:0006633 41 0.016
glycerophospholipid metabolic process GO:0006650 71 0.016
hindbrain development GO:0030902 128 0.016
nucleoside phosphate biosynthetic process GO:1901293 79 0.016
organelle localization GO:0051640 179 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
acyl coa biosynthetic process GO:0071616 7 0.016
organelle fission GO:0048285 170 0.016
multicellular organismal signaling GO:0035637 91 0.016
acetyl coa metabolic process GO:0006084 8 0.016
phospholipid metabolic process GO:0006644 87 0.016
adult behavior GO:0030534 135 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
alpha amino acid metabolic process GO:1901605 59 0.016
multicellular organism growth GO:0035264 161 0.016
negative regulation of molecular function GO:0044092 258 0.016
regulation of secretion GO:0051046 274 0.016
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
ribose phosphate biosynthetic process GO:0046390 59 0.016
metencephalon development GO:0022037 89 0.016
monosaccharide biosynthetic process GO:0046364 44 0.016
alpha amino acid catabolic process GO:1901606 18 0.016
retinoid metabolic process GO:0001523 24 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
positive regulation of cellular amine metabolic process GO:0033240 5 0.016
protein localization to membrane GO:0072657 108 0.015
regulation of secretion by cell GO:1903530 249 0.015
regulation of fatty acid metabolic process GO:0019217 28 0.015
protein localization to organelle GO:0033365 185 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
protein targeting GO:0006605 143 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
myeloid leukocyte differentiation GO:0002573 119 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
cellular chemical homeostasis GO:0055082 215 0.015
digestive tract development GO:0048565 190 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
synaptic transmission GO:0007268 329 0.015
monocarboxylic acid transport GO:0015718 44 0.015
nucleotide catabolic process GO:0009166 217 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
urate transport GO:0015747 1 0.015
organic hydroxy compound biosynthetic process GO:1901617 77 0.015
cellular ion homeostasis GO:0006873 165 0.014
negative regulation of protein modification process GO:0031400 163 0.014
lipid homeostasis GO:0055088 63 0.014
protein processing GO:0016485 163 0.014
cell type specific apoptotic process GO:0097285 268 0.014
cerebellum development GO:0021549 77 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
epidermis development GO:0008544 187 0.014
digestive system development GO:0055123 200 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
transmission of nerve impulse GO:0019226 76 0.014
regulation of carbohydrate metabolic process GO:0006109 75 0.014
nadph regeneration GO:0006740 2 0.014
aromatic compound catabolic process GO:0019439 286 0.014
blood circulation GO:0008015 195 0.014
positive regulation of transferase activity GO:0051347 167 0.014
peroxisomal transport GO:0043574 4 0.014
cellular amino acid biosynthetic process GO:0008652 22 0.014
cellular alcohol biosynthetic process GO:0044108 3 0.014
gluconeogenesis GO:0006094 39 0.014
regulation of lipid metabolic process GO:0019216 118 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
negative regulation of phosphorylation GO:0042326 166 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
metal ion homeostasis GO:0055065 189 0.013
anatomical structure homeostasis GO:0060249 145 0.013
response to metal ion GO:0010038 47 0.013
amino acid transmembrane transport GO:0003333 37 0.013
appendage morphogenesis GO:0035107 149 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
bone development GO:0060348 120 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
dicarboxylic acid metabolic process GO:0043648 18 0.013
ear development GO:0043583 200 0.013
spermatid development GO:0007286 108 0.013
urogenital system development GO:0001655 261 0.013
compound eye development GO:0048749 1 0.013
asymmetric stem cell division GO:0098722 3 0.013
vitamin d biosynthetic process GO:0042368 3 0.013
regulation of cellular response to stress GO:0080135 159 0.013
response to radiation GO:0009314 165 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
regulation of cell activation GO:0050865 289 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
tissue homeostasis GO:0001894 115 0.013
dna metabolic process GO:0006259 303 0.013
response to lipopolysaccharide GO:0032496 128 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
ras protein signal transduction GO:0007265 77 0.013
sphingolipid metabolic process GO:0006665 45 0.013
action potential GO:0001508 78 0.013
cardiac septum development GO:0003279 59 0.013
adiponectin activated signaling pathway GO:0033211 4 0.013
ribonucleoside catabolic process GO:0042454 206 0.012
cardiac chamber morphogenesis GO:0003206 93 0.012
ribonucleotide biosynthetic process GO:0009260 59 0.012
regulation of glucose metabolic process GO:0010906 60 0.012
heart morphogenesis GO:0003007 178 0.012
regulation of mapk cascade GO:0043408 248 0.012
protein import GO:0017038 101 0.012
cofactor catabolic process GO:0051187 6 0.012
amide transport GO:0042886 138 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
skeletal system morphogenesis GO:0048705 203 0.012
nucleoside catabolic process GO:0009164 206 0.012
cellular response to lipid GO:0071396 145 0.012
vitamin d3 metabolic process GO:0070640 3 0.012
cardiac chamber development GO:0003205 108 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
chromatin modification GO:0016568 187 0.012
response to drug GO:0042493 75 0.012
hormone secretion GO:0046879 128 0.012
glycerolipid biosynthetic process GO:0045017 50 0.012
purine nucleotide biosynthetic process GO:0006164 65 0.012
epithelial cell proliferation GO:0050673 174 0.012
regulation of fat cell differentiation GO:0045598 81 0.012
neuronal action potential GO:0019228 54 0.012
peptide hormone secretion GO:0030072 109 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
triglyceride metabolic process GO:0006641 51 0.012
response to starvation GO:0042594 65 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
rhythmic process GO:0048511 174 0.012
carbohydrate homeostasis GO:0033500 128 0.012
protein ubiquitination GO:0016567 171 0.012
sequestering of calcium ion GO:0051208 18 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
developmental maturation GO:0021700 193 0.012
rho protein signal transduction GO:0007266 32 0.011
negative regulation of immune system process GO:0002683 209 0.011
fatty acid derivative metabolic process GO:1901568 33 0.011
divalent inorganic cation transport GO:0072511 178 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
protein catabolic process GO:0030163 221 0.011
circulatory system process GO:0003013 197 0.011
regulation of hydrolase activity GO:0051336 246 0.011
amino acid transport GO:0006865 61 0.011
defense response to other organism GO:0098542 197 0.011
calcium ion homeostasis GO:0055074 127 0.011
nucleoside biosynthetic process GO:0009163 21 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
endocytosis GO:0006897 168 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
renal system development GO:0072001 225 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
cellular response to acid chemical GO:0071229 68 0.011
lateral inhibition GO:0046331 1 0.011
lipid transport GO:0006869 98 0.011
regulation of protein localization GO:0032880 231 0.011
steroid biosynthetic process GO:0006694 47 0.011
stem cell development GO:0048864 219 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
purine ribonucleoside biosynthetic process GO:0046129 19 0.011
nuclear transport GO:0051169 139 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
limb development GO:0060173 166 0.011
protein import into peroxisome matrix GO:0016558 3 0.011
organic hydroxy compound transport GO:0015850 93 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
regulation of ion transmembrane transporter activity GO:0032412 54 0.011
regulation of map kinase activity GO:0043405 120 0.011
myeloid cell differentiation GO:0030099 233 0.011
sequestering of metal ion GO:0051238 19 0.011
cellular biogenic amine metabolic process GO:0006576 28 0.011
response to acid chemical GO:0001101 111 0.011
atp metabolic process GO:0046034 75 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
nuclear division GO:0000280 158 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.010
fatty acid transmembrane transport GO:1902001 1 0.010
glycogen metabolic process GO:0005977 32 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.010
regulation of neuron differentiation GO:0045664 281 0.010
response to peptide GO:1901652 136 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
organ growth GO:0035265 117 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
long chain fatty acid import GO:0044539 2 0.010
negative regulation of cytokine production GO:0001818 84 0.010
epithelial cell development GO:0002064 159 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
plasma membrane organization GO:0007009 90 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
gonad development GO:0008406 141 0.010
brown fat cell differentiation GO:0050873 36 0.010
cellular macromolecule catabolic process GO:0044265 206 0.010
response to growth factor GO:0070848 198 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
innate immune response GO:0045087 157 0.010
positive regulation of kinase activity GO:0033674 155 0.010
regulation of ion transport GO:0043269 215 0.010

Entpd5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.074
inherited metabolic disorder DOID:655 0 0.051
amino acid metabolic disorder DOID:9252 0 0.028
nervous system disease DOID:863 0 0.020
disease of anatomical entity DOID:7 0 0.020
carbohydrate metabolic disorder DOID:2978 0 0.015
disease of cellular proliferation DOID:14566 0 0.013
central nervous system disease DOID:331 0 0.013
cardiovascular system disease DOID:1287 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
musculoskeletal system disease DOID:17 0 0.011