Mus musculus

188 known processes

Ephb2

Eph receptor B2

(Aliases: Hek5,Qek5,Drt,Prkm5,ETECK,Nuk,Tyro5,Cek5,Sek3,Erk)

Ephb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ephrin receptor signaling pathway GO:0048013 20 1.000
fasciculation of motor neuron axon GO:0097156 2 1.000
Mouse
dendritic spine organization GO:0097061 26 1.000
negative chemotaxis GO:0050919 14 1.000
Mouse
regulation of dendritic spine morphogenesis GO:0061001 17 1.000
Mouse
dendritic spine morphogenesis GO:0060997 22 1.000
regulation of dendritic spine development GO:0060998 22 1.000
Mouse
dendritic spine development GO:0060996 30 0.999
negative regulation of dendrite development GO:2000171 9 0.999
negative regulation of dendritic spine morphogenesis GO:0061002 3 0.999
regulation of rho gtpase activity GO:0032319 58 0.999
Mouse
central nervous system projection neuron axonogenesis GO:0021952 21 0.998
regulation of ras gtpase activity GO:0032318 88 0.997
Mouse
amine metabolic process GO:0009308 45 0.997
small gtpase mediated signal transduction GO:0007264 97 0.997
rap protein signal transduction GO:0032486 3 0.996
regulation of ras protein signal transduction GO:0046578 114 0.996
Mouse
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.995
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.995
single organismal cell cell adhesion GO:0016337 131 0.995
Mouse
negative regulation of dendritic spine development GO:0061000 3 0.995
regulation of cellular amine metabolic process GO:0033238 20 0.994
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.993
lens morphogenesis in camera type eye GO:0002089 24 0.992
Mouse
regulation of rho protein signal transduction GO:0035023 71 0.991
Mouse
ras protein signal transduction GO:0007265 77 0.991
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.991
retinal ganglion cell axon guidance GO:0031290 18 0.990
mitral valve morphogenesis GO:0003183 4 0.989
embryonic organ morphogenesis GO:0048562 276 0.986
regulation of cell projection organization GO:0031344 206 0.985
regulation of purine nucleotide catabolic process GO:0033121 122 0.984
Mouse
negative regulation of synapse assembly GO:0051964 3 0.984
Mouse
cell adhesion GO:0007155 329 0.983
Mouse
central nervous system neuron development GO:0021954 67 0.982
regulation of rac protein signal transduction GO:0035020 19 0.981
Mouse
axon guidance GO:0007411 141 0.981
regulation of neuron projection development GO:0010975 169 0.981
regulation of protein serine threonine kinase activity GO:0071900 157 0.980
Mouse
endocardial cushion to mesenchymal transition GO:0090500 5 0.978
actin cytoskeleton organization GO:0030036 220 0.976
Mouse
mitral valve development GO:0003174 4 0.976
regulation of protein kinase activity GO:0045859 232 0.975
Mouse
regulation of protein autophosphorylation GO:0031952 8 0.974
Mouse
regulation of actin cytoskeleton organization GO:0032956 84 0.974
Mouse
gtp metabolic process GO:0046039 144 0.973
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.968
negative regulation of neuron differentiation GO:0045665 101 0.965
epithelium migration GO:0090132 63 0.965
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.963
Mouse
developmental maturation GO:0021700 193 0.962
Mouse Worm
regulation of epithelial to mesenchymal transition GO:0010717 22 0.962
Mouse
regulation of neuron differentiation GO:0045664 281 0.962
negative regulation of cell projection organization GO:0031345 56 0.960
regulation of cellular ketone metabolic process GO:0010565 66 0.960
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.959
Mouse
epithelial tube morphogenesis GO:0060562 303 0.958
Mouse
regulation of nucleoside metabolic process GO:0009118 130 0.957
Mouse
negative regulation of ovulation GO:0060280 1 0.957
Worm
regulation of rac gtpase activity GO:0032314 13 0.956
Mouse
fasciculation of sensory neuron axon GO:0097155 3 0.954
Mouse
notochord formation GO:0014028 5 0.954
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.952
Mouse
central nervous system neuron differentiation GO:0021953 162 0.951
rho protein signal transduction GO:0007266 32 0.946
parathyroid hormone secretion GO:0035898 2 0.945
Mouse
t cell activation GO:0042110 289 0.945
substrate dependent cell migration GO:0006929 18 0.943
Mouse
neural tube development GO:0021915 160 0.941
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.940
Mouse
regulation of gtp catabolic process GO:0033124 113 0.940
Mouse
single organism cell adhesion GO:0098602 156 0.939
Mouse
ribonucleotide metabolic process GO:0009259 291 0.939
Mouse
regulation of stem cell differentiation GO:2000736 50 0.938
Mouse
positive regulation of rho gtpase activity GO:0032321 41 0.937
regulation of cellular amino acid metabolic process GO:0006521 5 0.937
regulation of nucleotide metabolic process GO:0006140 169 0.937
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.934
dendrite development GO:0016358 115 0.933
purine ribonucleotide catabolic process GO:0009154 208 0.933
Mouse
corpus callosum development GO:0022038 10 0.933
ribonucleoside metabolic process GO:0009119 245 0.929
Mouse
cellular response to glucose stimulus GO:0071333 45 0.928
Mouse
epithelial cell migration GO:0010631 63 0.928
Mouse
purine nucleoside catabolic process GO:0006152 205 0.927
Mouse
central nervous system neuron axonogenesis GO:0021955 28 0.927
peptidyl tyrosine modification GO:0018212 145 0.926
camera type eye development GO:0043010 266 0.923
negative regulation of nervous system development GO:0051961 156 0.915
regulation of transferase activity GO:0051338 263 0.914
Mouse
synapse organization GO:0050808 125 0.912
regulation of hormone levels GO:0010817 211 0.910
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.907
Mouse
positive regulation of actin filament bundle assembly GO:0032233 11 0.906
Mouse
leukocyte differentiation GO:0002521 342 0.905
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.904
Mouse
positive regulation of map kinase activity GO:0043406 84 0.904
Mouse
cellular ketone metabolic process GO:0042180 84 0.901
regulation of kinase activity GO:0043549 249 0.900
Mouse
positive regulation of synapse assembly GO:0051965 18 0.899
notochord development GO:0030903 20 0.896
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.895
Mouse
hormone secretion GO:0046879 128 0.893
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.889
Mouse
regulation of organelle organization GO:0033043 289 0.888
Mouse
nucleotide metabolic process GO:0009117 332 0.888
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.888
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.888
Mouse
regulation of cell migration GO:0030334 219 0.887
Mouse
nucleotide catabolic process GO:0009166 217 0.885
Mouse
purine containing compound catabolic process GO:0072523 213 0.884
Mouse
regulation of secretion GO:0051046 274 0.881
Mouse
regulation of endothelial cell migration GO:0010594 22 0.878
Mouse
glycosyl compound catabolic process GO:1901658 206 0.871
Mouse
negative regulation of neuron projection development GO:0010977 50 0.869
gtp catabolic process GO:0006184 143 0.863
Mouse
sensory perception of temperature stimulus GO:0050951 9 0.859
Mouse
negative regulation of cell proliferation GO:0008285 296 0.856
cell recognition GO:0008037 83 0.856
regulation of map kinase activity GO:0043405 120 0.854
Mouse
purine nucleoside metabolic process GO:0042278 241 0.853
Mouse
chemotaxis GO:0006935 247 0.853
peptide transport GO:0015833 133 0.849
Mouse
positive regulation of stress fiber assembly GO:0051496 9 0.847
Mouse
myeloid cell differentiation GO:0030099 233 0.846
Mouse
positive regulation of mapk cascade GO:0043410 170 0.845
Mouse
regulation of blood vessel endothelial cell migration GO:0043535 12 0.844
Mouse
carbohydrate homeostasis GO:0033500 128 0.842
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.842
Mouse
regulation of cellular catabolic process GO:0031329 242 0.839
Mouse
purine nucleotide metabolic process GO:0006163 302 0.838
Mouse
positive regulation of cell development GO:0010720 237 0.838
mapk cascade GO:0000165 281 0.833
Mouse
endothelial cell migration GO:0043542 44 0.832
Mouse
glucose homeostasis GO:0042593 128 0.832
Mouse
regulation of peptide transport GO:0090087 91 0.832
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.832
cellular response to hexose stimulus GO:0071331 47 0.828
Mouse
actin filament bundle assembly GO:0051017 40 0.825
Mouse
peptidyl amino acid modification GO:0018193 336 0.824
organonitrogen compound catabolic process GO:1901565 264 0.819
Mouse
neural precursor cell proliferation GO:0061351 121 0.817
Mouse
rac protein signal transduction GO:0016601 13 0.814
angiogenesis GO:0001525 201 0.809
purine nucleotide catabolic process GO:0006195 211 0.807
Mouse
activation of mapk activity GO:0000187 59 0.807
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.806
axonogenesis GO:0007409 274 0.801
regulation of peptide hormone secretion GO:0090276 75 0.801
Mouse
axonal fasciculation GO:0007413 15 0.798
positive regulation of nervous system development GO:0051962 221 0.791
negative regulation of cell development GO:0010721 169 0.790
peptide secretion GO:0002790 114 0.789
Mouse
forebrain development GO:0030900 302 0.787
aromatic compound catabolic process GO:0019439 286 0.785
Mouse
negative regulation of epithelial to mesenchymal transition GO:0010719 6 0.780
heterocycle catabolic process GO:0046700 280 0.779
Mouse
cellular amine metabolic process GO:0044106 44 0.777
neuron recognition GO:0008038 25 0.776
glycosyl compound metabolic process GO:1901657 246 0.776
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.772
Mouse
positive regulation of cellular component biogenesis GO:0044089 94 0.767
positive regulation of kinase activity GO:0033674 155 0.764
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.764
Mouse
phospholipid metabolic process GO:0006644 87 0.761
Mouse
regulation of rap protein signal transduction GO:0032487 6 0.756
Mouse
regulation of hydrolase activity GO:0051336 246 0.756
Mouse
blood vessel morphogenesis GO:0048514 285 0.755
embryonic epithelial tube formation GO:0001838 130 0.755
ribonucleoside catabolic process GO:0042454 206 0.754
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.751
Mouse
axial mesoderm development GO:0048318 8 0.751
Mouse
ameboidal type cell migration GO:0001667 128 0.749
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.748
Mouse
regulation of secretion by cell GO:1903530 249 0.746
Mouse
synapse assembly GO:0007416 56 0.744
nucleoside catabolic process GO:0009164 206 0.736
Mouse
notochord morphogenesis GO:0048570 10 0.735
Mouse
cellular amino acid metabolic process GO:0006520 103 0.730
amide transport GO:0042886 138 0.729
Mouse
regulation of hormone secretion GO:0046883 88 0.728
Mouse
cellular glucose homeostasis GO:0001678 52 0.727
Mouse
regulation of cell adhesion GO:0030155 154 0.721
Mouse
positive regulation of cell activation GO:0050867 158 0.719
ribose phosphate metabolic process GO:0019693 291 0.718
Mouse
actin filament organization GO:0007015 113 0.716
Mouse
positive regulation of transferase activity GO:0051347 167 0.715
Mouse
regulation of endopeptidase activity GO:0052548 89 0.713
Mouse
nucleoside metabolic process GO:0009116 246 0.711
Mouse
regulation of epithelial cell migration GO:0010632 35 0.710
Mouse
regulation of body fluid levels GO:0050878 162 0.707
stress activated protein kinase signaling cascade GO:0031098 81 0.702
Mouse
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.698
blood vessel endothelial cell migration GO:0043534 23 0.698
Mouse
aortic valve morphogenesis GO:0003180 4 0.695
regulation of cysteine type endopeptidase activity GO:2000116 65 0.693
Mouse
commissural neuron axon guidance GO:0071679 8 0.692
heart morphogenesis GO:0003007 178 0.690
Mouse
thymus development GO:0048538 41 0.687
Mouse
cellular response to monosaccharide stimulus GO:0071326 47 0.684
Mouse
neuron remodeling GO:0016322 7 0.680
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.673
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.671
Mouse
organophosphate catabolic process GO:0046434 232 0.664
Mouse
sensory organ morphogenesis GO:0090596 242 0.663
cranial nerve morphogenesis GO:0021602 26 0.661
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.657
Mouse
positive regulation of protein modification process GO:0031401 299 0.657
Mouse
positive regulation of ras gtpase activity GO:0032320 65 0.657
regulation of vasculature development GO:1901342 88 0.650
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.645
Mouse
positive regulation of jnk cascade GO:0046330 46 0.644
Mouse
neuron projection guidance GO:0097485 141 0.643
regulation of cell adhesion mediated by integrin GO:0033628 13 0.643
Mouse
positive regulation of neuron projection development GO:0010976 79 0.641
morphogenesis of embryonic epithelium GO:0016331 159 0.637
Worm
regulation of astrocyte differentiation GO:0048710 20 0.626
Mouse
nitrogen compound transport GO:0071705 271 0.620
Mouse
t cell proliferation GO:0042098 120 0.619
motor neuron axon guidance GO:0008045 26 0.618
Mouse
regulation of actin filament based process GO:0032970 99 0.615
Mouse
tissue migration GO:0090130 68 0.614
Mouse
cell chemotaxis GO:0060326 81 0.609
Mouse
pigment metabolic process GO:0042440 32 0.605
Fly
adult behavior GO:0030534 135 0.600
Mouse
regulation of axon guidance GO:1902667 13 0.600
nucleobase containing small molecule metabolic process GO:0055086 352 0.599
Mouse
lymphocyte proliferation GO:0046651 164 0.598
neural tube formation GO:0001841 108 0.590
positive regulation of gtpase activity GO:0043547 85 0.589
osteoclast differentiation GO:0030316 62 0.586
Mouse
regulation of peptide secretion GO:0002791 77 0.585
Mouse
ear development GO:0043583 200 0.578
nucleoside phosphate catabolic process GO:1901292 222 0.574
Mouse
regulation of actin filament bundle assembly GO:0032231 18 0.572
Mouse
regulation of cell motility GO:2000145 236 0.569
Mouse
cell adhesion mediated by integrin GO:0033627 18 0.568
Mouse
response to monosaccharide GO:0034284 67 0.565
Mouse
mammary gland epithelial cell proliferation GO:0033598 24 0.564
Mouse
hindbrain formation GO:0021576 1 0.563
positive regulation of cytoskeleton organization GO:0051495 49 0.563
Mouse
mesenchymal cell differentiation GO:0048762 107 0.562
Mouse
urogenital system development GO:0001655 261 0.557
leukocyte proliferation GO:0070661 172 0.552
optic nerve development GO:0021554 8 0.552
jnk cascade GO:0007254 72 0.550
Mouse
gland development GO:0048732 330 0.549
Mouse
positive regulation of cell projection organization GO:0031346 95 0.549
tube formation GO:0035148 140 0.546
peptide hormone secretion GO:0030072 109 0.538
Mouse
epithelial cell development GO:0002064 159 0.534
Mouse
regulation of homeostatic process GO:0032844 182 0.531
Mouse
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.530
branching morphogenesis of an epithelial tube GO:0048754 159 0.519
Mouse
neuroblast proliferation GO:0007405 49 0.518
corticospinal tract morphogenesis GO:0021957 6 0.517
Mouse
limbic system development GO:0021761 72 0.513
Mouse
optic nerve morphogenesis GO:0021631 6 0.505
regulation of keratinocyte proliferation GO:0010837 15 0.504
cell fate commitment GO:0045165 210 0.503
negative regulation of neuron projection regeneration GO:0070571 3 0.502
Mouse
positive regulation of anagen GO:0051885 1 0.499
skeletal system development GO:0001501 356 0.499
Mouse
positive regulation of organelle organization GO:0010638 128 0.494
Mouse
mesonephric duct morphogenesis GO:0072180 4 0.494
carbohydrate derivative catabolic process GO:1901136 231 0.491
Mouse
hindbrain development GO:0030902 128 0.490
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.490
regulation of mapk cascade GO:0043408 248 0.486
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.482
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.479
Mouse
cerebellar granule cell precursor tangential migration GO:0021935 1 0.478
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.475
melanin metabolic process GO:0006582 12 0.471
Fly
regulation of axon extension GO:0030516 43 0.468
lens development in camera type eye GO:0002088 62 0.466
Mouse
hippocampus development GO:0021766 52 0.455
Mouse
palate development GO:0060021 76 0.451
regulation of angiogenesis GO:0045765 81 0.448
Mouse
negative regulation of cellular component organization GO:0051129 194 0.447
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.447
post anal tail morphogenesis GO:0036342 23 0.441
Mouse
retina development in camera type eye GO:0060041 119 0.441
epidermis development GO:0008544 187 0.441
skeletal system morphogenesis GO:0048705 203 0.441
establishment of organ orientation GO:0048561 1 0.440
cardiac epithelial to mesenchymal transition GO:0060317 18 0.438
regulation of cellular response to stress GO:0080135 159 0.437
Mouse
telencephalon development GO:0021537 186 0.437
ear morphogenesis GO:0042471 118 0.434
inner ear morphogenesis GO:0042472 101 0.434
ribonucleotide catabolic process GO:0009261 208 0.431
Mouse
epithelial to mesenchymal transition GO:0001837 47 0.429
Mouse
detection of temperature stimulus involved in sensory perception GO:0050961 6 0.429
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.426
Mouse
cellular response to carbohydrate stimulus GO:0071322 50 0.424
Mouse
regulation of peptidase activity GO:0052547 96 0.420
Mouse
hypophysis morphogenesis GO:0048850 3 0.416
regulation of striated muscle cell differentiation GO:0051153 81 0.412
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.406
Mouse
positive regulation of t cell activation GO:0050870 101 0.406
negative regulation of synapse maturation GO:2000297 2 0.402
renal vesicle induction GO:0072034 3 0.402
lung field specification GO:0060424 3 0.400
cell substrate adhesion GO:0031589 130 0.397
midbrain hindbrain boundary maturation GO:0021732 1 0.396
regulation of gliogenesis GO:0014013 50 0.395
Mouse
primary neural tube formation GO:0014020 95 0.392
positive regulation of neuroblast proliferation GO:0002052 19 0.390
regionalization GO:0003002 337 0.390
stress activated mapk cascade GO:0051403 80 0.387
Mouse
cellular homeostasis GO:0019725 240 0.387
Mouse
notochord cell differentiation GO:0060034 1 0.384
Mouse
mesonephric duct formation GO:0072181 2 0.378
regulation of stress activated mapk cascade GO:0032872 69 0.377
Mouse
positive regulation of apoptotic process GO:0043065 217 0.376
Mouse
regulation of ovulation GO:0060278 3 0.376
Worm
regulation of t cell proliferation GO:0042129 92 0.372
regulation of synapse assembly GO:0051963 29 0.372
mesenchymal cell development GO:0014031 93 0.369
Mouse
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.368
Mouse
regulation of stress fiber assembly GO:0051492 15 0.366
Mouse
embryonic placenta development GO:0001892 98 0.364
limb morphogenesis GO:0035108 149 0.363
respiratory system development GO:0060541 190 0.362
central nervous system vasculogenesis GO:0022009 3 0.360
insulin secretion GO:0030073 89 0.357
Mouse
regulation of jun kinase activity GO:0043506 40 0.351
Mouse
positive regulation of stress activated mapk cascade GO:0032874 48 0.350
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.349
embryonic skeletal system development GO:0048706 120 0.349
positive regulation of leukocyte proliferation GO:0070665 73 0.347
negative regulation of axon guidance GO:1902668 8 0.347
regulation of long term neuronal synaptic plasticity GO:0048169 19 0.347
ossification GO:0001503 216 0.345
Mouse
cellular lipid metabolic process GO:0044255 323 0.342
Mouse
dorsal ventral axon guidance GO:0033563 3 0.342
lymphocyte differentiation GO:0030098 242 0.342
positive regulation of nucleotide catabolic process GO:0030813 88 0.340
spinal cord development GO:0021510 81 0.336
bone remodeling GO:0046849 53 0.335
Mouse
neural tube closure GO:0001843 90 0.333
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.333
embryonic appendage morphogenesis GO:0035113 126 0.330
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.329
negative regulation of axon extension GO:0030517 19 0.328
asymmetric neuroblast division GO:0055059 1 0.328
positive regulation of cell death GO:0010942 224 0.325
Mouse
regulation of cellular component size GO:0032535 121 0.324
neuron maturation GO:0042551 29 0.323
Mouse
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.322
embryonic digit morphogenesis GO:0042733 56 0.309
nephron tubule morphogenesis GO:0072078 68 0.308
formation of primary germ layer GO:0001704 77 0.307
Mouse
stem cell development GO:0048864 219 0.302
Mouse
regulation of anatomical structure size GO:0090066 178 0.301
regulation of jnk cascade GO:0046328 62 0.299
Mouse
mammary gland epithelium development GO:0061180 65 0.297
Mouse
axon extension involved in axon guidance GO:0048846 14 0.295
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.293
purine containing compound metabolic process GO:0072521 311 0.293
Mouse
skin development GO:0043588 220 0.292
forebrain neuron development GO:0021884 30 0.292
gastrulation GO:0007369 116 0.292
Mouse
locomotory behavior GO:0007626 195 0.291
Mouse
germ cell development GO:0007281 185 0.291
Worm
response to transforming growth factor beta GO:0071559 88 0.291
positive regulation of neuron death GO:1901216 28 0.288
Mouse
muscular septum morphogenesis GO:0003150 4 0.288
cellular response to organonitrogen compound GO:0071417 145 0.288
tissue remodeling GO:0048771 102 0.288
Mouse
detection of stimulus involved in sensory perception GO:0050906 44 0.285
Mouse
wound healing GO:0042060 157 0.282
mesoderm morphogenesis GO:0048332 64 0.279
Mouse
negative regulation of immune system process GO:0002683 209 0.278
negative regulation of hepatocyte differentiation GO:0070367 1 0.276
transdifferentiation GO:0060290 1 0.274
notochord cell development GO:0060035 1 0.274
Mouse
mammary gland morphogenesis GO:0060443 54 0.273
Mouse
muscle cell differentiation GO:0042692 261 0.273
regulation of leukocyte differentiation GO:1902105 159 0.273
regulation of cell activation GO:0050865 289 0.272
lung induction GO:0060492 3 0.269
anatomical structure maturation GO:0071695 49 0.268
stem cell differentiation GO:0048863 268 0.266
Mouse
digestive system development GO:0055123 200 0.265
Mouse
oxygen homeostasis GO:0032364 2 0.263
oogenesis GO:0048477 56 0.263
Worm
cranial nerve development GO:0021545 41 0.262
positive regulation of lipid metabolic process GO:0045834 40 0.262
Mouse
cell cell junction organization GO:0045216 72 0.261
nephron epithelium morphogenesis GO:0072088 68 0.255
appendage development GO:0048736 166 0.255
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.255
positive regulation of lipid kinase activity GO:0090218 11 0.255
Mouse
positive regulation of neuron apoptotic process GO:0043525 25 0.251
Mouse
learning GO:0007612 98 0.250
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.250
positive regulation of programmed cell death GO:0043068 218 0.250
Mouse
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.249
Mouse
spinal cord ventral commissure morphogenesis GO:0021965 2 0.249
kidney development GO:0001822 213 0.248
positive regulation of lymphocyte activation GO:0051251 140 0.246
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.241
neuron apoptotic process GO:0051402 142 0.240
Mouse
endocrine hormone secretion GO:0060986 15 0.240
Mouse
negative regulation of response to wounding GO:1903035 77 0.238
Mouse
establishment or maintenance of cell polarity GO:0007163 86 0.237
Mouse
renal inner medulla development GO:0072053 3 0.237
digestive tract morphogenesis GO:0048546 147 0.236
Mouse
cardiac muscle cell differentiation GO:0055007 69 0.235
ribonucleoside triphosphate metabolic process GO:0009199 220 0.232
Mouse
cop9 signalosome assembly GO:0010387 2 0.232
metal ion homeostasis GO:0055065 189 0.229
Mouse
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.228
regulation of leukocyte proliferation GO:0070663 121 0.227
skeletal muscle organ development GO:0060538 163 0.226
neuron projection regeneration GO:0031102 14 0.226
Mouse
neural crest cell differentiation GO:0014033 54 0.225
organelle assembly GO:0070925 177 0.224
positive regulation of lymphocyte proliferation GO:0050671 70 0.224
innate immune response GO:0045087 157 0.222
Fly
skeletal muscle cell differentiation GO:0035914 66 0.221
organic hydroxy compound metabolic process GO:1901615 203 0.220
Fly
regulation of nucleotide catabolic process GO:0030811 122 0.220
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.219
Mouse
positive regulation of cardiac muscle cell differentiation GO:2000727 6 0.219
regulation of neuron apoptotic process GO:0043523 122 0.218
Mouse
heart valve development GO:0003170 23 0.218
regulation of synaptic plasticity GO:0048167 87 0.215
neuron death GO:0070997 154 0.214
Mouse
detection of temperature stimulus involved in sensory perception of pain GO:0050965 6 0.214
Mouse
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.214
regulation of lipid kinase activity GO:0043550 14 0.214
Mouse
neuron projection extension GO:1990138 64 0.213
branchiomotor neuron axon guidance GO:0021785 7 0.213
regulation of podosome assembly GO:0071801 3 0.213
regulation of cellular component biogenesis GO:0044087 181 0.212
positive regulation of gtp catabolic process GO:0033126 85 0.212
cell growth GO:0016049 130 0.211
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation GO:0044343 1 0.211
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 11 0.208
Mouse
t cell differentiation GO:0030217 174 0.206
positive regulation of protein complex assembly GO:0031334 45 0.205
adult walking behavior GO:0007628 41 0.203
Mouse
planar cell polarity pathway involved in neural tube closure GO:0090179 14 0.203
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.202
endoderm development GO:0007492 45 0.200
auditory receptor cell fate determination GO:0042668 3 0.198
mitotic cell cycle GO:0000278 195 0.197
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.196
embryonic body morphogenesis GO:0010172 10 0.196
Worm
regulation of neuron death GO:1901214 134 0.195
Mouse
hematopoietic stem cell proliferation GO:0071425 13 0.195
cellular chemical homeostasis GO:0055082 215 0.195
Mouse
wnt signaling pathway GO:0016055 188 0.194
compound eye development GO:0048749 1 0.194
regulation of proteolysis GO:0030162 164 0.193
Mouse
protein processing GO:0016485 163 0.193
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.191
paraxial mesodermal cell differentiation GO:0048342 2 0.189
regulation of bmp signaling pathway GO:0030510 60 0.186
olfactory bulb interneuron development GO:0021891 7 0.184
regulation of endocytosis GO:0030100 69 0.183
heart valve formation GO:0003188 10 0.181
positive regulation of hydrolase activity GO:0051345 148 0.181
regulation of auditory receptor cell differentiation GO:0045607 4 0.180
body morphogenesis GO:0010171 45 0.180
Worm
positive regulation of nucleotide metabolic process GO:0045981 114 0.178
negative regulation of chemotaxis GO:0050922 11 0.177
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.175
renal outer medulla development GO:0072054 2 0.175
kidney rudiment formation GO:0072003 3 0.175
substrate adhesion dependent cell spreading GO:0034446 30 0.174
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.173
cerebellum formation GO:0021588 1 0.171
female gamete generation GO:0007292 74 0.171
Worm
regulation of vesicle mediated transport GO:0060627 139 0.171
organelle localization GO:0051640 179 0.169
regulation of protein binding GO:0043393 60 0.168
negative regulation of t cell differentiation GO:0045581 23 0.168
positive regulation of cell cell adhesion mediated by cadherin GO:2000049 2 0.167
apoptotic signaling pathway GO:0097190 306 0.167
postganglionic parasympathetic nervous system development GO:0021784 2 0.167
immune effector process GO:0002252 321 0.165
Fly
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.165
morphogenesis of a branching epithelium GO:0061138 193 0.164
Mouse
neural crest cell migration GO:0001755 32 0.163
activation of immune response GO:0002253 138 0.163
regulation of epithelial cell proliferation GO:0050678 141 0.162
rhombomere morphogenesis GO:0021593 2 0.162
nephric duct formation GO:0072179 4 0.161
negative regulation of prostatic bud formation GO:0060686 4 0.161
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.160
podosome assembly GO:0071800 6 0.160
axon target recognition GO:0007412 4 0.158
regulation of cell shape GO:0008360 39 0.158
eye photoreceptor cell differentiation GO:0001754 41 0.157
organonitrogen compound biosynthetic process GO:1901566 192 0.157
metanephros development GO:0001656 79 0.156

Ephb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org