Mus musculus

0 known processes

Eppk1

epiplakin 1

(Aliases: EPPK,6230424I18Rik,EPIPL,EPIPL1)

Eppk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ras protein signal transduction GO:0007265 77 0.089
small gtpase mediated signal transduction GO:0007264 97 0.071
cellular nitrogen compound catabolic process GO:0044270 280 0.056
leukocyte differentiation GO:0002521 342 0.054
purine containing compound metabolic process GO:0072521 311 0.052
aromatic compound catabolic process GO:0019439 286 0.052
nucleoside phosphate metabolic process GO:0006753 338 0.050
heterocycle catabolic process GO:0046700 280 0.049
rho protein signal transduction GO:0007266 32 0.047
t cell activation GO:0042110 289 0.045
wound healing GO:0042060 157 0.044
cytokine production GO:0001816 319 0.044
purine nucleotide metabolic process GO:0006163 302 0.043
cellular amino acid metabolic process GO:0006520 103 0.040
ribonucleoside triphosphate metabolic process GO:0009199 220 0.040
regulation of membrane potential GO:0042391 192 0.039
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.039
response to organonitrogen compound GO:0010243 246 0.038
nucleotide metabolic process GO:0009117 332 0.038
mapk cascade GO:0000165 281 0.037
organic cyclic compound catabolic process GO:1901361 295 0.037
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
transmembrane transport GO:0055085 412 0.037
actin cytoskeleton organization GO:0030036 220 0.037
regulation of organelle organization GO:0033043 289 0.037
ribose phosphate metabolic process GO:0019693 291 0.036
amine metabolic process GO:0009308 45 0.036
apoptotic signaling pathway GO:0097190 306 0.035
rhythmic process GO:0048511 174 0.035
regulation of transferase activity GO:0051338 263 0.034
developmental maturation GO:0021700 193 0.034
ribonucleotide metabolic process GO:0009259 291 0.034
macromolecule catabolic process GO:0009057 281 0.034
regulation of cellular catabolic process GO:0031329 242 0.034
cytokine mediated signaling pathway GO:0019221 115 0.034
purine ribonucleoside catabolic process GO:0046130 205 0.033
purine ribonucleotide metabolic process GO:0009150 290 0.033
nucleoside triphosphate catabolic process GO:0009143 205 0.033
organophosphate catabolic process GO:0046434 232 0.033
cellular response to organonitrogen compound GO:0071417 145 0.032
glycosyl compound catabolic process GO:1901658 206 0.032
nucleoside triphosphate metabolic process GO:0009141 230 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.031
cellular ketone metabolic process GO:0042180 84 0.031
gland development GO:0048732 330 0.031
nucleotide catabolic process GO:0009166 217 0.031
cellular amine metabolic process GO:0044106 44 0.030
regulation of cellular ketone metabolic process GO:0010565 66 0.030
purine nucleoside triphosphate metabolic process GO:0009144 226 0.030
ribonucleoside catabolic process GO:0042454 206 0.030
regulation of reactive oxygen species metabolic process GO:2000377 40 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
transmission of nerve impulse GO:0019226 76 0.029
nucleoside catabolic process GO:0009164 206 0.029
ribonucleotide catabolic process GO:0009261 208 0.029
reactive oxygen species metabolic process GO:0072593 84 0.029
defense response to bacterium GO:0042742 119 0.029
positive regulation of protein modification process GO:0031401 299 0.028
multicellular organismal homeostasis GO:0048871 164 0.028
regulation of system process GO:0044057 200 0.028
purine ribonucleotide catabolic process GO:0009154 208 0.028
immune effector process GO:0002252 321 0.028
purine nucleoside triphosphate catabolic process GO:0009146 203 0.027
regulation of nucleotide metabolic process GO:0006140 169 0.027
placenta development GO:0001890 140 0.027
organelle assembly GO:0070925 177 0.027
regulation of cellular amino acid metabolic process GO:0006521 5 0.027
action potential GO:0001508 78 0.027
regulation of cell projection organization GO:0031344 206 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.026
purine nucleotide catabolic process GO:0006195 211 0.026
cellular homeostasis GO:0019725 240 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
ribonucleoside metabolic process GO:0009119 245 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
epithelial cell proliferation GO:0050673 174 0.025
regulation of cell cycle GO:0051726 281 0.025
anatomical structure homeostasis GO:0060249 145 0.025
cell adhesion GO:0007155 329 0.025
epidermis development GO:0008544 187 0.025
regulation of nucleotide catabolic process GO:0030811 122 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.025
regulation of t cell activation GO:0050863 170 0.025
regulation of kinase activity GO:0043549 249 0.024
neuronal action potential GO:0019228 54 0.024
regulation of ras protein signal transduction GO:0046578 114 0.024
response to organic cyclic compound GO:0014070 198 0.024
regulation of renal sodium excretion GO:0035813 3 0.024
purine ribonucleoside metabolic process GO:0046128 241 0.024
regulation of cytokine production GO:0001817 266 0.023
sensory organ morphogenesis GO:0090596 242 0.023
regulation of establishment of protein localization GO:0070201 181 0.023
regulation of mapk cascade GO:0043408 248 0.023
positive regulation of cellular catabolic process GO:0031331 148 0.023
positive regulation of mapk cascade GO:0043410 170 0.023
regulation of defense response GO:0031347 233 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
multicellular organismal signaling GO:0035637 91 0.022
renal sodium excretion GO:0035812 3 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
activation of immune response GO:0002253 138 0.022
epithelial cell development GO:0002064 159 0.022
extrinsic apoptotic signaling pathway GO:0097191 126 0.021
protein catabolic process GO:0030163 221 0.021
spermatogenesis GO:0007283 284 0.021
myeloid leukocyte differentiation GO:0002573 119 0.021
regulation of body fluid levels GO:0050878 162 0.021
positive regulation of transferase activity GO:0051347 167 0.021
leukocyte mediated immunity GO:0002443 174 0.021
regulation of hydrolase activity GO:0051336 246 0.020
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
purine containing compound catabolic process GO:0072523 213 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
cell recognition GO:0008037 83 0.020
positive regulation of protein kinase activity GO:0045860 144 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
lymphocyte proliferation GO:0046651 164 0.020
regulation of hormone levels GO:0010817 211 0.020
molting cycle GO:0042303 90 0.020
cell type specific apoptotic process GO:0097285 268 0.020
respiratory system development GO:0060541 190 0.020
purine nucleoside catabolic process GO:0006152 205 0.020
cellular response to cytokine stimulus GO:0071345 189 0.020
negative regulation of cell proliferation GO:0008285 296 0.019
positive regulation of cytokine production GO:0001819 174 0.019
mitotic cell cycle GO:0000278 195 0.019
extracellular matrix organization GO:0030198 147 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
gtp metabolic process GO:0046039 144 0.019
regulation of proteolysis GO:0030162 164 0.019
ossification GO:0001503 216 0.019
chemotaxis GO:0006935 247 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
locomotory behavior GO:0007626 195 0.019
myeloid dendritic cell chemotaxis GO:0002408 2 0.019
lipid biosynthetic process GO:0008610 179 0.019
lung development GO:0030324 164 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
camera type eye development GO:0043010 266 0.019
cellular response to inorganic substance GO:0071241 37 0.019
extracellular structure organization GO:0043062 148 0.019
i kappab kinase nf kappab signaling GO:0007249 85 0.018
skin development GO:0043588 220 0.018
regulation of homeostatic process GO:0032844 182 0.018
intermediate filament cytoskeleton organization GO:0045104 26 0.018
regionalization GO:0003002 337 0.018
cellular lipid metabolic process GO:0044255 323 0.018
blastocyst development GO:0001824 80 0.018
male gamete generation GO:0048232 285 0.018
carbohydrate metabolic process GO:0005975 230 0.018
leukocyte proliferation GO:0070661 172 0.018
regulation of purine nucleotide catabolic process GO:0033121 122 0.018
inflammatory response GO:0006954 244 0.018
response to acid chemical GO:0001101 111 0.018
intermediate filament based process GO:0045103 27 0.017
peptidyl amino acid modification GO:0018193 336 0.017
blood circulation GO:0008015 195 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
positive regulation of ras gtpase activity GO:0032320 65 0.017
reactive nitrogen species metabolic process GO:2001057 0 0.017
protein processing GO:0016485 163 0.017
regulation of anatomical structure size GO:0090066 178 0.017
nitrogen compound transport GO:0071705 271 0.016
regulation of protein catabolic process GO:0042176 108 0.016
response to extracellular stimulus GO:0009991 127 0.016
muscle system process GO:0003012 141 0.016
ventricular cardiac muscle cell action potential GO:0086005 4 0.016
negative regulation of molecular function GO:0044092 258 0.016
regulation of cell migration GO:0030334 219 0.016
regulation of protein localization GO:0032880 231 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
cellular response to amino acid stimulus GO:0071230 29 0.016
ear development GO:0043583 200 0.016
regulation of epithelial cell proliferation GO:0050678 141 0.016
detection of stimulus GO:0051606 84 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
regulation of renin secretion into blood stream GO:1900133 4 0.016
leukocyte migration GO:0050900 124 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
defense response to other organism GO:0098542 197 0.016
positive regulation of cellular amine metabolic process GO:0033240 5 0.016
hormone metabolic process GO:0042445 86 0.016
gtp catabolic process GO:0006184 143 0.016
skeletal system development GO:0001501 356 0.016
regulation of protein kinase activity GO:0045859 232 0.016
intermediate filament organization GO:0045109 15 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
response to amino acid GO:0043200 37 0.015
cellular response to lipid GO:0071396 145 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
response to inorganic substance GO:0010035 96 0.015
divalent inorganic cation transport GO:0072511 178 0.015
microtubule based process GO:0007017 236 0.015
protein ubiquitination GO:0016567 171 0.015
regulation of response to wounding GO:1903034 189 0.015
regulation of cellular amine metabolic process GO:0033238 20 0.015
lymphocyte mediated immunity GO:0002449 139 0.015
positive regulation of podosome assembly GO:0071803 3 0.015
cellular protein catabolic process GO:0044257 155 0.015
nucleoside metabolic process GO:0009116 246 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.015
muscle cell differentiation GO:0042692 261 0.015
lymphocyte differentiation GO:0030098 242 0.015
positive regulation of nucleotide catabolic process GO:0030813 88 0.015
multicellular organism growth GO:0035264 161 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
cell activation involved in immune response GO:0002263 126 0.015
endomembrane system organization GO:0010256 147 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
binding of sperm to zona pellucida GO:0007339 34 0.015
nuclear division GO:0000280 158 0.015
vitamin d3 metabolic process GO:0070640 3 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
adaptive immune response GO:0002250 155 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
actin filament depolymerization GO:0030042 15 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.014
ensheathment of neurons GO:0007272 76 0.014
tissue remodeling GO:0048771 102 0.014
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.014
regulation of secretion by cell GO:1903530 249 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
cellular alcohol metabolic process GO:0044107 3 0.014
mitotic cell cycle process GO:1903047 159 0.014
synaptic transmission GO:0007268 329 0.014
regulation of lymphocyte differentiation GO:0045619 107 0.014
glucose homeostasis GO:0042593 128 0.014
tissue homeostasis GO:0001894 115 0.014
hormone secretion GO:0046879 128 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
ion transmembrane transport GO:0034220 361 0.014
oxidation reduction process GO:0055114 342 0.014
alpha beta t cell activation GO:0046631 91 0.014
positive regulation of innate immune response GO:0045089 80 0.014
cytokine biosynthetic process GO:0042089 68 0.014
sensory perception GO:0007600 245 0.014
positive regulation of gtpase activity GO:0043547 85 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
chromatin organization GO:0006325 206 0.014
interspecies interaction between organisms GO:0044419 83 0.014
maintenance of location GO:0051235 89 0.014
dna metabolic process GO:0006259 303 0.014
t cell proliferation GO:0042098 120 0.013
keratinocyte differentiation GO:0030216 48 0.013
regulation of membrane depolarization during action potential GO:0098902 1 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
homeostasis of number of cells GO:0048872 210 0.013
cation homeostasis GO:0055080 212 0.013
regulation of cell activation GO:0050865 289 0.013
cytokine metabolic process GO:0042107 71 0.013
positive regulation of gtp catabolic process GO:0033126 85 0.013
cellular modified amino acid metabolic process GO:0006575 63 0.013
regulation of carbohydrate metabolic process GO:0006109 75 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
regulation of ras gtpase activity GO:0032318 88 0.013
lymphocyte activation involved in immune response GO:0002285 93 0.013
regulation of action potential GO:0098900 4 0.013
positive regulation of kinase activity GO:0033674 155 0.013
cellular response to peptide GO:1901653 92 0.013
positive regulation of immune effector process GO:0002699 107 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.013
response to lipopolysaccharide GO:0032496 128 0.013
regulation of cellular response to stress GO:0080135 159 0.013
response to oxygen levels GO:0070482 62 0.013
axonogenesis GO:0007409 274 0.013
monosaccharide metabolic process GO:0005996 106 0.013
heart morphogenesis GO:0003007 178 0.013
circulatory system process GO:0003013 197 0.013
actin filament organization GO:0007015 113 0.013
negative regulation of cell activation GO:0050866 111 0.013
positive regulation of nervous system development GO:0051962 221 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
protein maturation GO:0051604 176 0.013
actin filament based movement GO:0030048 23 0.013
regulation of t cell differentiation GO:0045580 83 0.013
drug metabolic process GO:0017144 4 0.013
regulation of t cell proliferation GO:0042129 92 0.012
negative regulation of cell cycle GO:0045786 123 0.012
positive regulation of defense response GO:0031349 124 0.012
organelle fission GO:0048285 170 0.012
rna interference GO:0016246 2 0.012
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.012
cellular ion homeostasis GO:0006873 165 0.012
regulation of rho protein signal transduction GO:0035023 71 0.012
regulation of podosome assembly GO:0071801 3 0.012
neural tube development GO:0021915 160 0.012
cell maturation GO:0048469 127 0.012
sperm egg recognition GO:0035036 37 0.012
positive regulation of cell death GO:0010942 224 0.012
striated muscle tissue development GO:0014706 293 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
compound eye development GO:0048749 1 0.012
response to insulin GO:0032868 100 0.012
regulation of gtp catabolic process GO:0033124 113 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.012
response to peptide GO:1901652 136 0.012
negative regulation of hormone biosynthetic process GO:0032353 4 0.012
metal ion homeostasis GO:0055065 189 0.012
respiratory tube development GO:0030323 167 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
intracellular protein transport GO:0006886 204 0.012
regulation of multi organism process GO:0043900 111 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
regulation of muscle system process GO:0090257 80 0.012
response to iron ion GO:0010039 4 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
stress activated mapk cascade GO:0051403 80 0.012
response to starvation GO:0042594 65 0.012
immune response regulating signaling pathway GO:0002764 125 0.012
positive regulation of organelle organization GO:0010638 128 0.012
innate immune response GO:0045087 157 0.012
learning or memory GO:0007611 148 0.012
regulation of cell motility GO:2000145 236 0.012
response to nutrient levels GO:0031667 109 0.012
striated muscle contraction GO:0006941 45 0.012
fat soluble vitamin biosynthetic process GO:0042362 4 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
regulation of stress activated mapk cascade GO:0032872 69 0.011
cellular response to external stimulus GO:0071496 88 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
circadian rhythm GO:0007623 114 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
peptide transport GO:0015833 133 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
peptide secretion GO:0002790 114 0.011
cellular response to acid chemical GO:0071229 68 0.011
cellular response to insulin stimulus GO:0032869 78 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
regulation of intracellular transport GO:0032386 159 0.011
negative regulation of protein processing GO:0010955 79 0.011
regulation of map kinase activity GO:0043405 120 0.011
oocyte axis specification GO:0007309 2 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
negative regulation of lymphocyte activation GO:0051250 91 0.011
cellular alcohol biosynthetic process GO:0044108 3 0.011
atp metabolic process GO:0046034 75 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
oocyte construction GO:0007308 2 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
cofactor transport GO:0051181 4 0.011
actin polymerization or depolymerization GO:0008154 54 0.011
vesicle localization GO:0051648 86 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
regulation of systemic arterial blood pressure by atrial natriuretic peptide GO:0003050 2 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
cell growth GO:0016049 130 0.011
leukocyte mediated cytotoxicity GO:0001909 62 0.011
negative regulation of t cell activation GO:0050868 65 0.011
b cell activation GO:0042113 161 0.011
response to metal ion GO:0010038 47 0.011
embryonic placenta development GO:0001892 98 0.011
regulation of actin filament based process GO:0032970 99 0.011
cellular response to peptidoglycan GO:0071224 4 0.011
negative regulation of multi organism process GO:0043901 68 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
muscle tissue development GO:0060537 308 0.011
negative regulation of hydrolase activity GO:0051346 71 0.011
glucose metabolic process GO:0006006 92 0.011
adult behavior GO:0030534 135 0.011
regulation of protein maturation GO:1903317 96 0.010
hexose metabolic process GO:0019318 98 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
drug catabolic process GO:0042737 2 0.010
response to growth factor GO:0070848 198 0.010
leukocyte chemotaxis GO:0030595 69 0.010
plasma membrane organization GO:0007009 90 0.010
regulation of cell adhesion GO:0030155 154 0.010
cell killing GO:0001906 67 0.010
cytoplasmic transport GO:0016482 234 0.010
cellular chemical homeostasis GO:0055082 215 0.010
cardiac chamber development GO:0003205 108 0.010
development of primary sexual characteristics GO:0045137 143 0.010
regulation of defense response to bacterium GO:1900424 3 0.010
protein localization to organelle GO:0033365 185 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
amide transport GO:0042886 138 0.010
cardiac muscle tissue development GO:0048738 130 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.010
carboxylic acid biosynthetic process GO:0046394 86 0.010
t cell differentiation GO:0030217 174 0.010
detection of abiotic stimulus GO:0009582 60 0.010
regulation of glucose metabolic process GO:0010906 60 0.010
negative regulation of proteolysis GO:0045861 74 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010
endocytosis GO:0006897 168 0.010

Eppk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.048
disease of anatomical entity DOID:7 0 0.048
nervous system disease DOID:863 0 0.028
cardiovascular system disease DOID:1287 0 0.019
sensory system disease DOID:0050155 0 0.015
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
connective tissue disease DOID:65 0 0.014
muscular disease DOID:0080000 0 0.013
muscle tissue disease DOID:66 0 0.012
myopathy DOID:423 0 0.012
heart disease DOID:114 0 0.012
cardiomyopathy DOID:0050700 0 0.012
intrinsic cardiomyopathy DOID:0060036 0 0.012
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.012
gastrointestinal system disease DOID:77 0 0.012
organ system cancer DOID:0050686 0 0.011
bone disease DOID:0080001 0 0.011