Mus musculus

268 known processes

Erbb2

v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

(Aliases: c-erbB2,HER-2,mKIAA3023,HER2,c-neu,Erbb-2,Neu)

Erbb2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
axon guidance GO:0007411 141 0.998
axonogenesis GO:0007409 274 0.998
neuron projection guidance GO:0097485 141 0.997
chemotaxis GO:0006935 247 0.995
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.992
Fly
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.991
Mouse
stem cell development GO:0048864 219 0.989
Zebrafish Mouse Fly
ameboidal type cell migration GO:0001667 128 0.988
Zebrafish Mouse Fly
ovulation GO:0030728 15 0.983
Worm
skeletal muscle organ development GO:0060538 163 0.978
Rat
cranial nerve development GO:0021545 41 0.975
Zebrafish Mouse
urogenital system development GO:0001655 261 0.974
Fly
cell adhesion GO:0007155 329 0.972
Human Fly
kidney development GO:0001822 213 0.968
rho protein signal transduction GO:0007266 32 0.966
positive regulation of heart growth GO:0060421 18 0.961
Mouse
single organismal cell cell adhesion GO:0016337 131 0.958
Fly
nephron epithelium morphogenesis GO:0072088 68 0.957
t cell activation GO:0042110 289 0.953
autonomic nervous system development GO:0048483 43 0.951
Rat
guanosine containing compound catabolic process GO:1901069 144 0.945
axon target recognition GO:0007412 4 0.940
negative regulation of immature t cell proliferation GO:0033087 3 0.936
pallium development GO:0021543 120 0.933
Mouse
nerve development GO:0021675 67 0.932
Zebrafish Mouse
camera type eye development GO:0043010 266 0.923
kidney epithelium development GO:0072073 121 0.923
mesenchymal cell development GO:0014031 93 0.916
Zebrafish Mouse
negative regulation of ovulation GO:0060280 1 0.915
intracellular protein transport GO:0006886 204 0.909
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.908
neural crest cell migration GO:0001755 32 0.908
Zebrafish Mouse
positive regulation of nervous system development GO:0051962 221 0.906
morphogenesis of embryonic epithelium GO:0016331 159 0.905
Fly
hindbrain development GO:0030902 128 0.904
olfactory bulb interneuron differentiation GO:0021889 12 0.904
Mouse
ras protein signal transduction GO:0007265 77 0.900
Rat
digestive tract development GO:0048565 190 0.898
Mouse Fly
wound healing GO:0042060 157 0.895
Human Zebrafish Mouse Fly
motor neuron axon guidance GO:0008045 26 0.894
negative regulation of nervous system development GO:0051961 156 0.892
dendrite extension GO:0097484 3 0.891
negative regulation of synapse assembly GO:0051964 3 0.890
nephron morphogenesis GO:0072028 69 0.890
oocyte axis specification GO:0007309 2 0.889
Fly
digestive tract morphogenesis GO:0048546 147 0.888
Mouse Fly
oocyte differentiation GO:0009994 35 0.881
Fly
digestive system development GO:0055123 200 0.874
Mouse Fly
olfactory lobe development GO:0021988 32 0.873
Mouse
response to amino acid GO:0043200 37 0.871
Mouse
epidermis development GO:0008544 187 0.870
Mouse
mesenchyme development GO:0060485 152 0.868
Zebrafish Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.864
positive regulation of neuron maturation GO:0014042 2 0.857
glycosyl compound metabolic process GO:1901657 246 0.855
negative regulation of cell proliferation GO:0008285 296 0.855
epithelial tube morphogenesis GO:0060562 303 0.854
Fly
nephron tubule morphogenesis GO:0072078 68 0.853
ribonucleotide catabolic process GO:0009261 208 0.851
sensory organ morphogenesis GO:0090596 242 0.851
Fly
salivary gland morphogenesis GO:0007435 33 0.850
Mouse
hair follicle development GO:0001942 85 0.848
Mouse
regulation of rho protein signal transduction GO:0035023 71 0.845
ureteric bud morphogenesis GO:0060675 62 0.836
cell fate commitment GO:0045165 210 0.832
Mouse Fly
retinal blood vessel morphogenesis GO:0061304 3 0.829
stem cell differentiation GO:0048863 268 0.822
Zebrafish Mouse Fly
protein localization to membrane GO:0072657 108 0.814
central nervous system neuron differentiation GO:0021953 162 0.813
Mouse
wnt signaling pathway GO:0016055 188 0.809
regulation of neuron projection development GO:0010975 169 0.808
mesonephric tubule morphogenesis GO:0072171 63 0.808
regulation of epithelial cell proliferation GO:0050678 141 0.806
Human Mouse
oocyte construction GO:0007308 2 0.804
Fly
positive regulation of cell development GO:0010720 237 0.803
peripheral nervous system development GO:0007422 53 0.791
lymphocyte proliferation GO:0046651 164 0.791
metencephalon development GO:0022037 89 0.783
pigment metabolic process GO:0042440 32 0.783
positive regulation of neuron differentiation GO:0045666 141 0.782
purine nucleoside metabolic process GO:0042278 241 0.781
rhombomere morphogenesis GO:0021593 2 0.767
neuron projection extension GO:1990138 64 0.766
negative regulation of cellular component organization GO:0051129 194 0.763
preganglionic parasympathetic nervous system development GO:0021783 17 0.760
endocardial cushion development GO:0003197 26 0.759
Mouse
forebrain cell migration GO:0021885 58 0.757
Mouse
neural crest cell differentiation GO:0014033 54 0.756
Zebrafish Mouse
odontogenesis GO:0042476 78 0.754
response to peptide hormone GO:0043434 127 0.748
small gtpase mediated signal transduction GO:0007264 97 0.745
Rat
extrinsic apoptotic signaling pathway GO:0097191 126 0.745
glomerular epithelial cell development GO:0072310 6 0.743
schwann cell development GO:0014044 22 0.743
Zebrafish
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.733
Fly
mammary gland morphogenesis GO:0060443 54 0.732
Rat
bmp signaling pathway GO:0030509 93 0.731
mesenchymal cell differentiation GO:0048762 107 0.729
Zebrafish Mouse
mammary gland epithelium development GO:0061180 65 0.728
Mouse
gland development GO:0048732 330 0.727
Mouse Rat Fly
regulation of neuron differentiation GO:0045664 281 0.726
membrane organization GO:0061024 245 0.726
neuron recognition GO:0008038 25 0.725
Zebrafish
embryonic placenta development GO:0001892 98 0.725
Mouse
regulation of gtp catabolic process GO:0033124 113 0.721
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.721
Mouse
embryonic organ morphogenesis GO:0048562 276 0.720
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.713
Human Mouse
purine nucleotide metabolic process GO:0006163 302 0.712
purine containing compound catabolic process GO:0072523 213 0.708
schwann cell differentiation GO:0014037 26 0.706
Zebrafish Mouse
mesoderm formation GO:0001707 62 0.705
epithelial tube formation GO:0072175 130 0.703
regulation of t cell differentiation GO:0045580 83 0.702
sensory perception GO:0007600 245 0.700
cerebral cortex development GO:0021987 86 0.695
Mouse
cardiac muscle tissue development GO:0048738 130 0.694
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.692
positive regulation of rho gtpase activity GO:0032321 41 0.692
establishment of protein localization to organelle GO:0072594 118 0.690
Mouse
positive regulation of nucleotide catabolic process GO:0030813 88 0.687
rhombomere 5 development GO:0021571 4 0.681
morphogenesis of a polarized epithelium GO:0001738 37 0.680
Fly
response to growth factor GO:0070848 198 0.679
negative regulation of neuron differentiation GO:0045665 101 0.678
multicellular organismal signaling GO:0035637 91 0.676
neural crest cell development GO:0014032 48 0.675
Zebrafish Mouse
cranial nerve morphogenesis GO:0021602 26 0.673
pons development GO:0021548 13 0.673
synaptic transmission GO:0007268 329 0.668
t cell differentiation in thymus GO:0033077 77 0.667
regulation of t cell activation GO:0050863 170 0.665
cellular amino acid metabolic process GO:0006520 103 0.662
negative regulation of t cell differentiation GO:0045581 23 0.660
positive regulation of fibroblast proliferation GO:0048146 20 0.656
Mouse
regulation of hydrolase activity GO:0051336 246 0.653
rhombomere 3 morphogenesis GO:0021658 2 0.652
cellular ketone metabolic process GO:0042180 84 0.651
regulation of ras gtpase activity GO:0032318 88 0.642
nephron tubule development GO:0072080 84 0.641
regulation of mitotic cell cycle phase transition GO:1901990 73 0.629
Fly
formation of radial glial scaffolds GO:0021943 4 0.625
myelination GO:0042552 74 0.624
embryonic skeletal system morphogenesis GO:0048704 91 0.619
lateral line system development GO:0048925 1 0.618
Zebrafish
positive regulation of intracellular transport GO:0032388 70 0.618
Mouse
axonal fasciculation GO:0007413 15 0.616
Zebrafish
parasympathetic nervous system development GO:0048486 19 0.615
segmentation GO:0035282 93 0.605
Fly
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.605
Mouse
response to organonitrogen compound GO:0010243 246 0.603
Mouse
regulation of ovulation GO:0060278 3 0.602
positive regulation of ras gtpase activity GO:0032320 65 0.601
ribonucleoside metabolic process GO:0009119 245 0.601
negative regulation of neuron projection development GO:0010977 50 0.600
facial nerve morphogenesis GO:0021610 11 0.598
negative regulation of epithelial cell proliferation GO:0050680 64 0.596
regulation of lymphocyte proliferation GO:0050670 117 0.595
cellular response to organonitrogen compound GO:0071417 145 0.594
Mouse
nucleoside metabolic process GO:0009116 246 0.591
protein localization to nucleus GO:0034504 121 0.591
Mouse
neuron maturation GO:0042551 29 0.591
positive regulation of intracellular protein transport GO:0090316 42 0.584
Mouse
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.582
ribonucleoside triphosphate catabolic process GO:0009203 199 0.582
developmental maturation GO:0021700 193 0.574
Fly
ear development GO:0043583 200 0.571
cell junction organization GO:0034330 77 0.571
brain segmentation GO:0035284 3 0.570
secondary metabolic process GO:0019748 18 0.570
placenta development GO:0001890 140 0.570
Mouse
canonical wnt signaling pathway GO:0060070 130 0.569
protein depolymerization GO:0051261 34 0.566
regulation of cell motility GO:2000145 236 0.566
Mouse
purine nucleotide catabolic process GO:0006195 211 0.564
cilium assembly GO:0042384 81 0.563
positive regulation of neuron projection development GO:0010976 79 0.561
development of primary sexual characteristics GO:0045137 143 0.561
Fly
metanephric nephron development GO:0072210 34 0.560
nuclear transport GO:0051169 139 0.557
Mouse
leukocyte proliferation GO:0070661 172 0.557
leukocyte differentiation GO:0002521 342 0.556
cell maturation GO:0048469 127 0.555
Fly
negative regulation of wnt signaling pathway GO:0030178 73 0.549
transmission of nerve impulse GO:0019226 76 0.549
positive regulation of cellular amine metabolic process GO:0033240 5 0.549
neuromuscular process GO:0050905 99 0.548
regulation of axon extension GO:0030516 43 0.547
regulation of wnt signaling pathway GO:0030111 123 0.547
lymphocyte differentiation GO:0030098 242 0.541
neuron neuron synaptic transmission GO:0007270 69 0.536
positive regulation of gtp catabolic process GO:0033126 85 0.536
morphogenesis of a branching epithelium GO:0061138 193 0.535
organophosphate catabolic process GO:0046434 232 0.532
regulation of muscle tissue development GO:1901861 97 0.531
Mouse
hindbrain tangential cell migration GO:0021934 2 0.531
neuronal action potential GO:0019228 54 0.529
establishment or maintenance of cell polarity GO:0007163 86 0.527
Fly
renal system development GO:0072001 225 0.526
Fly
smoothened signaling pathway GO:0007224 105 0.526
intermediate filament cytoskeleton organization GO:0045104 26 0.524
stat protein import into nucleus GO:0007262 6 0.516
Mouse
negative regulation of lymphocyte proliferation GO:0050672 45 0.516
ribonucleoside catabolic process GO:0042454 206 0.515
protein targeting GO:0006605 143 0.514
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.509
cerebral cortex cell migration GO:0021795 44 0.504
Mouse
positive regulation of nucleoside metabolic process GO:0045979 91 0.503
response to peptide GO:1901652 136 0.502
skeletal muscle cell differentiation GO:0035914 66 0.500
cellular nitrogen compound catabolic process GO:0044270 280 0.499
nucleocytoplasmic transport GO:0006913 139 0.496
Mouse
regulation of cell projection organization GO:0031344 206 0.494
forebrain generation of neurons GO:0021872 63 0.493
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 95 0.490
negative regulation of t cell proliferation GO:0042130 38 0.489
regulation of cell size GO:0008361 72 0.487
forebrain development GO:0030900 302 0.487
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.486
regulation of organ morphogenesis GO:2000027 144 0.484
Fly
stem cell fate commitment GO:0048865 5 0.484
Fly
positive regulation of gtpase activity GO:0043547 85 0.483
mammary gland lobule development GO:0061377 22 0.480
Mouse
mammary gland involution GO:0060056 9 0.480
Rat
regulation of stat protein import into nucleus GO:2000364 2 0.476
Mouse
angiogenesis GO:0001525 201 0.474
positive regulation of cytoplasmic transport GO:1903651 40 0.474
Mouse
positive regulation of protein import into nucleus GO:0042307 26 0.474
Mouse
epithelial cell proliferation GO:0050673 174 0.474
Human Mouse Fly
ensheathment of neurons GO:0007272 76 0.472
regulation of cell adhesion GO:0030155 154 0.471
Human
regulation of cellular catabolic process GO:0031329 242 0.470
cellular response to growth factor stimulus GO:0071363 197 0.469
kidney morphogenesis GO:0060993 83 0.468
rhombomere 3 development GO:0021569 4 0.466
branching morphogenesis of an epithelial tube GO:0048754 159 0.465
regulation of cell activation GO:0050865 289 0.465
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.465
regulation of intracellular protein transport GO:0033157 82 0.464
Mouse
cell substrate adhesion GO:0031589 130 0.463
establishment of planar polarity GO:0001736 28 0.462
Fly
positive regulation of muscle tissue development GO:1901863 32 0.455
Mouse
regulation of cell migration GO:0030334 219 0.452
Mouse
amine metabolic process GO:0009308 45 0.450
striated muscle tissue development GO:0014706 293 0.449
Mouse Rat
regulation of ras protein signal transduction GO:0046578 114 0.448
regulation of mapk cascade GO:0043408 248 0.446
Human Rat
neural tube closure GO:0001843 90 0.446
glucose import GO:0046323 32 0.444
cell growth GO:0016049 130 0.442
Human
skin development GO:0043588 220 0.441
Mouse
regulation of glucose transport GO:0010827 32 0.438
male sex differentiation GO:0046661 109 0.437
Worm
rac protein signal transduction GO:0016601 13 0.437
regulation of canonical wnt signaling pathway GO:0060828 82 0.437
regulation of leukocyte proliferation GO:0070663 121 0.431
cardiac muscle cell differentiation GO:0055007 69 0.430
cellular protein complex disassembly GO:0043624 36 0.429
embryonic epithelial tube formation GO:0001838 130 0.424
negative regulation of mitotic cell cycle GO:0045930 58 0.422
Fly
purine nucleoside triphosphate catabolic process GO:0009146 203 0.421
regulation of intracellular transport GO:0032386 159 0.419
Mouse
macromolecular complex disassembly GO:0032984 43 0.418
telencephalon cell migration GO:0022029 55 0.416
Mouse
response to insulin GO:0032868 100 0.416
cardiocyte differentiation GO:0035051 87 0.415
cilium morphogenesis GO:0060271 102 0.415
positive regulation of cell projection organization GO:0031346 95 0.414
regulation of cellular ketone metabolic process GO:0010565 66 0.411
melanin metabolic process GO:0006582 12 0.410
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.410
regulation of cellular amine metabolic process GO:0033238 20 0.409
regulation of cellular amino acid metabolic process GO:0006521 5 0.407
negative regulation of lymphocyte differentiation GO:0045620 32 0.406
mapk cascade GO:0000165 281 0.406
Human Rat
positive regulation of axon extension GO:0045773 20 0.405
molting cycle GO:0042303 90 0.404
Mouse
retina development in camera type eye GO:0060041 119 0.403
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.402
nerve growth factor signaling pathway GO:0038180 3 0.401
neural tube formation GO:0001841 108 0.400
renal tubule development GO:0061326 87 0.398
Fly
purine nucleoside triphosphate metabolic process GO:0009144 226 0.396
neural tube development GO:0021915 160 0.391
negative regulation of cell activation GO:0050866 111 0.391
regulation of heart growth GO:0060420 31 0.390
Mouse
regulation of nucleocytoplasmic transport GO:0046822 73 0.386
Mouse
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.386
detection of external stimulus GO:0009581 61 0.384
t cell proliferation GO:0042098 120 0.379
rhombomere formation GO:0021594 1 0.378
positive regulation of tyrosine phosphorylation of stat5 protein GO:0042523 6 0.377
Mouse
single organism cell adhesion GO:0098602 156 0.377
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.374
regulation of tyrosine phosphorylation of stat5 protein GO:0042522 8 0.373
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.373
response to fibroblast growth factor GO:0071774 47 0.371
positive regulation of protein modification process GO:0031401 299 0.370
cellular amine metabolic process GO:0044106 44 0.368
circulatory system process GO:0003013 197 0.368
Fly
mesoderm morphogenesis GO:0048332 64 0.367
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.366
regulation of t cell differentiation in thymus GO:0033081 24 0.365
positive regulation of cellular catabolic process GO:0031331 148 0.361
regulation of apoptotic signaling pathway GO:2001233 197 0.360
Fly
gonad development GO:0008406 141 0.355
Fly
facial nerve structural organization GO:0021612 10 0.354
protein complex disassembly GO:0043241 40 0.354
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.353
cell type specific apoptotic process GO:0097285 268 0.352
Mouse
cell junction assembly GO:0034329 52 0.352
developmental cell growth GO:0048588 84 0.351
sensory system development GO:0048880 3 0.350
Zebrafish
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.348
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.348
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 15 0.347
Mouse
regulation of protein depolymerization GO:1901879 26 0.346
synapse organization GO:0050808 125 0.346
renal tubule morphogenesis GO:0061333 72 0.344
Fly
regulation of protein serine threonine kinase activity GO:0071900 157 0.343
Human
dendrite development GO:0016358 115 0.341
asymmetric neuroblast division GO:0055059 1 0.340
regulation of t cell proliferation GO:0042129 92 0.339
ureteric bud development GO:0001657 94 0.339
carbohydrate derivative catabolic process GO:1901136 231 0.338
muscle cell differentiation GO:0042692 261 0.337
establishment of protein localization to membrane GO:0090150 54 0.333
genitalia development GO:0048806 37 0.333
Worm
heart growth GO:0060419 45 0.330
Mouse
axon regeneration GO:0031103 12 0.329
epithelial cell morphogenesis GO:0003382 41 0.325
nucleoside triphosphate metabolic process GO:0009141 230 0.324
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.324
oviduct development GO:0060066 3 0.321
peptidyl amino acid modification GO:0018193 336 0.320
Human Mouse Rat
carbohydrate transport GO:0008643 62 0.320
morphogenesis of a branching structure GO:0001763 203 0.318
t cell differentiation GO:0030217 174 0.317
negative regulation of cell cycle GO:0045786 123 0.317
Fly
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.316
Fly
adrenal cortex formation GO:0035802 2 0.314
negative regulation of t cell activation GO:0050868 65 0.314
stem cell maintenance GO:0019827 130 0.314
Fly
olfactory learning GO:0008355 2 0.313
Fly
nephron development GO:0072006 109 0.312
ribonucleoside triphosphate metabolic process GO:0009199 220 0.311
hindbrain morphogenesis GO:0021575 46 0.311
oocyte development GO:0048599 33 0.311
Fly
cognition GO:0050890 149 0.309
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.308
regulation of cardiac muscle tissue development GO:0055024 31 0.308
Mouse
sympathetic nervous system development GO:0048485 22 0.307
Rat
mechanoreceptor differentiation GO:0042490 67 0.306
olfactory bulb development GO:0021772 30 0.305
Mouse
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.303
Fly
rhombomere development GO:0021546 8 0.301
regulation of protein complex disassembly GO:0043244 28 0.300
hexose transport GO:0008645 56 0.299
regulation of protein tyrosine kinase activity GO:0061097 17 0.298
negative regulation of leukocyte differentiation GO:1902106 51 0.297
blood vessel morphogenesis GO:0048514 285 0.296
protein localization to organelle GO:0033365 185 0.295
Mouse
regulation of protein import into nucleus GO:0042306 52 0.293
Mouse
striated muscle cell proliferation GO:0014855 39 0.292
Mouse
regulation of neuron apoptotic process GO:0043523 122 0.292
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.291
response to acid chemical GO:0001101 111 0.290
Mouse
regulation of extent of cell growth GO:0061387 52 0.289
negative regulation of dendritic spine morphogenesis GO:0061002 3 0.289
female meiosis chromosome segregation GO:0016321 1 0.288
endocardial cell differentiation GO:0060956 4 0.286
lateral line nerve development GO:0048892 1 0.283
Zebrafish
regulation of tyrosine phosphorylation of stat protein GO:0042509 20 0.282
Mouse
positive regulation of protein transport GO:0051222 93 0.281
Mouse
female gamete generation GO:0007292 74 0.277
Worm Fly
embryonic skeletal system development GO:0048706 120 0.276
regulation of stem cell proliferation GO:0072091 78 0.272
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.272
regulation of establishment of protein localization GO:0070201 181 0.270
Mouse
positive regulation of wnt signaling pathway GO:0030177 45 0.270
protein import into nucleus GO:0006606 95 0.269
Mouse
muscle tissue development GO:0060537 308 0.265
Mouse Rat
cranial nerve structural organization GO:0021604 13 0.265
mesenchyme morphogenesis GO:0072132 32 0.265
formation of primary germ layer GO:0001704 77 0.263
signal transduction in absence of ligand GO:0038034 55 0.262
positive regulation of hydrolase activity GO:0051345 148 0.261
positive regulation of neuron death GO:1901216 28 0.261
regionalization GO:0003002 337 0.261
Fly
glial cell fate determination GO:0007403 3 0.260
nucleoside phosphate metabolic process GO:0006753 338 0.258
endocytosis GO:0006897 168 0.257
regulation of kinase activity GO:0043549 249 0.257
Human
learning or memory GO:0007611 148 0.256
Fly
regulation of jak stat cascade GO:0046425 34 0.254
Mouse
forebrain neuron differentiation GO:0021879 52 0.254
Mouse
notochord formation GO:0014028 5 0.254
negative regulation of protein depolymerization GO:1901880 21 0.252
positive regulation of cardiac muscle tissue development GO:0055025 19 0.249
Mouse
oligodendrocyte differentiation GO:0048709 53 0.247
regulation of fibroblast proliferation GO:0048145 34 0.247
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.243
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 18 0.241
Fly
adrenal cortex development GO:0035801 2 0.239
regulation of purine nucleotide catabolic process GO:0033121 122 0.239
limbic system development GO:0021761 72 0.238
immature t cell proliferation in thymus GO:0033080 7 0.238
monosaccharide transport GO:0015749 58 0.237
jak stat cascade GO:0007259 42 0.236
Mouse
mammary gland alveolus development GO:0060749 22 0.236
Mouse
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.236
mesonephric epithelium development GO:0072163 94 0.236
neuron apoptotic process GO:0051402 142 0.233
Mouse
positive regulation of epithelial cell proliferation GO:0050679 68 0.233
Human Mouse
nephron epithelium development GO:0072009 92 0.232
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.229
glucose transport GO:0015758 56 0.227
regulation of organ growth GO:0046620 61 0.225
Mouse
pharynx development GO:0060465 1 0.225
central nervous system segmentation GO:0035283 3 0.223
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.222
female gonad development GO:0008585 71 0.222
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.222
Mouse
formation of anatomical boundary GO:0048859 6 0.221
divalent inorganic cation homeostasis GO:0072507 138 0.221
cellular response to acid chemical GO:0071229 68 0.220
Mouse
regulation of dendritic spine development GO:0060998 22 0.220
lactation GO:0007595 25 0.216
Mouse
protein import GO:0017038 101 0.215
Mouse
mesenchymal to epithelial transition GO:0060231 12 0.215
positive regulation of mapk cascade GO:0043410 170 0.215
Human Rat
formation of organ boundary GO:0010160 1 0.214
developmental pigmentation GO:0048066 40 0.214
regulation of hippo signaling GO:0035330 1 0.213
gliogenesis GO:0042063 141 0.213
nucleotide catabolic process GO:0009166 217 0.212
cardiac muscle cell proliferation GO:0060038 31 0.212
Mouse
stem cell proliferation GO:0072089 117 0.211
regulation of membrane potential GO:0042391 192 0.208
negative regulation of cell cycle phase transition GO:1901988 48 0.208
Fly
organelle assembly GO:0070925 177 0.207
metanephric part of ureteric bud development GO:0035502 2 0.207
regulation of immature t cell proliferation in thymus GO:0033084 6 0.206
regulation of cellular component size GO:0032535 121 0.205
negative regulation of cell projection organization GO:0031345 56 0.205
mitotic cell cycle GO:0000278 195 0.204
Fly
gastrulation GO:0007369 116 0.204
negative regulation of protein metabolic process GO:0051248 282 0.203
positive regulation of glucose import GO:0046326 14 0.203
apoptotic signaling pathway GO:0097190 306 0.203
Fly
compound eye development GO:0048749 1 0.202
Fly
glial cell differentiation GO:0010001 131 0.202
action potential GO:0001508 78 0.201
microtubule polymerization or depolymerization GO:0031109 26 0.201
neuron migration GO:0001764 122 0.201
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.200
hair cycle GO:0042633 90 0.198
Mouse
muscle cell proliferation GO:0033002 52 0.198
Mouse
telencephalon development GO:0021537 186 0.198
Mouse
regulation of protein kinase activity GO:0045859 232 0.195
Human
peptidyl tyrosine modification GO:0018212 145 0.194
Human Mouse Rat
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.194
metanephric comma shaped body morphogenesis GO:0072278 1 0.193
ribose phosphate metabolic process GO:0019693 291 0.193
purine containing compound metabolic process GO:0072521 311 0.192
regulation of immature t cell proliferation GO:0033083 7 0.192
brain morphogenesis GO:0048854 32 0.190
regulation of actin cytoskeleton organization GO:0032956 84 0.189
morphogenesis of an epithelial sheet GO:0002011 27 0.189
cellular component assembly involved in morphogenesis GO:0010927 139 0.187
Fly
synapse assembly GO:0007416 56 0.187
regulation of mitotic cell cycle GO:0007346 126 0.187
Fly
positive regulation of striated muscle tissue development GO:0045844 31 0.186
Mouse
protein localization to plasma membrane GO:0072659 57 0.185
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.184
nucleoside catabolic process GO:0009164 206 0.183
regulation of wound healing GO:0061041 40 0.183
Fly
epidermal growth factor receptor signaling pathway GO:0007173 28 0.183
Mouse
focal adhesion assembly GO:0048041 19 0.182
regulation of synapse assembly GO:0051963 29 0.182
postganglionic parasympathetic nervous system development GO:0021784 2 0.181
ephrin receptor signaling pathway GO:0048013 20 0.181
nuclear import GO:0051170 95 0.181
Mouse
primary neural tube formation GO:0014020 95 0.180
pigmentation GO:0043473 71 0.180
regulation of protein transport GO:0051223 163 0.180
Mouse
cardiac muscle tissue growth GO:0055017 37 0.179
Mouse
gamma delta t cell differentiation GO:0042492 11 0.178
regulation of cell cycle phase transition GO:1901987 77 0.178
Fly
exocrine system development GO:0035272 45 0.177
Mouse Fly

Erbb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 0 0.317
disease of anatomical entity DOID:7 0 0.317
cardiovascular system disease DOID:1287 0 0.317
neuromuscular disease DOID:440 0 0.251
charcot marie tooth disease DOID:10595 0 0.251
nervous system disease DOID:863 0 0.251
neuropathy DOID:870 0 0.251