Mus musculus

50 known processes

Erbb3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

(Aliases: Erbb3r,Her3,Erbb-3,MGC117742,C76256)

Erbb3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
dendrite extension GO:0097484 3 1.000
axon target recognition GO:0007412 4 0.999
positive regulation of neuron maturation GO:0014042 2 0.998
axon guidance GO:0007411 141 0.992
Mouse
schwann cell development GO:0014044 22 0.990
Zebrafish
glial cell differentiation GO:0010001 131 0.986
positive regulation of cell maturation GO:1903431 4 0.985
nerve growth factor signaling pathway GO:0038180 3 0.983
autonomic nervous system development GO:0048483 43 0.980
hindbrain tangential cell migration GO:0021934 2 0.976
regulation of axon extension GO:0030516 43 0.974
oligodendrocyte differentiation GO:0048709 53 0.972
Mouse
neuron projection guidance GO:0097485 141 0.972
Mouse
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.970
enteric nervous system development GO:0048484 11 0.966
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.962
ensheathment of neurons GO:0007272 76 0.951
Zebrafish Mouse
synaptic transmission GO:0007268 329 0.951
positive regulation of cellular amine metabolic process GO:0033240 5 0.949
regulation of membrane potential GO:0042391 192 0.948
Zebrafish Mouse
peripheral nervous system development GO:0007422 53 0.941
sensory organ morphogenesis GO:0090596 242 0.939
Fly
cellular amine metabolic process GO:0044106 44 0.932
schwann cell differentiation GO:0014037 26 0.931
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.928
Mouse
heart trabecula morphogenesis GO:0061384 26 0.927
cellular ketone metabolic process GO:0042180 84 0.924
organic acid transport GO:0015849 101 0.923
positive regulation of axon extension GO:0045773 20 0.921
stem cell fate determination GO:0048867 2 0.920
cell adhesion GO:0007155 329 0.915
Human Fly
negative regulation of cell proliferation GO:0008285 296 0.914
Mouse
gamma aminobutyric acid signaling pathway GO:0007214 8 0.912
kidney epithelium development GO:0072073 121 0.911
stem cell development GO:0048864 219 0.910
Zebrafish Mouse Fly
neuron projection extension GO:1990138 64 0.909
gliogenesis GO:0042063 141 0.907
kidney development GO:0001822 213 0.904
multicellular organismal signaling GO:0035637 91 0.898
Zebrafish Mouse
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.895
Human
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.894
regulation of cellular component size GO:0032535 121 0.894
oocyte axis specification GO:0007309 2 0.891
Fly
action potential GO:0001508 78 0.890
Zebrafish Mouse
nerve development GO:0021675 67 0.884
regulation of cell size GO:0008361 72 0.879
regulation of neuron projection development GO:0010975 169 0.872
stem cell differentiation GO:0048863 268 0.871
Zebrafish Mouse Fly
stem cell fate commitment GO:0048865 5 0.868
Fly
regulation of cellular amine metabolic process GO:0033238 20 0.867
negative regulation of synaptic transmission gabaergic GO:0032229 2 0.867
signal transduction in absence of ligand GO:0038034 55 0.863
Human
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.863
Mouse
ear development GO:0043583 200 0.856
extrinsic apoptotic signaling pathway GO:0097191 126 0.855
Human
positive regulation of neuron differentiation GO:0045666 141 0.847
glial cell fate commitment GO:0021781 14 0.846
sympathetic nervous system development GO:0048485 22 0.844
glial cell fate determination GO:0007403 3 0.831
response to growth factor GO:0070848 198 0.831
cell growth GO:0016049 130 0.828
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.827
myelination GO:0042552 74 0.826
Zebrafish Mouse
cranial nerve development GO:0021545 41 0.822
lateral line nerve development GO:0048892 1 0.812
Zebrafish
anion transport GO:0006820 177 0.810
regulation of cell growth GO:0001558 91 0.805
regulation of kinase activity GO:0043549 249 0.803
Human
regulation of neuron differentiation GO:0045664 281 0.803
positive regulation of nervous system development GO:0051962 221 0.802
axonogenesis GO:0007409 274 0.801
Mouse Rat
neuron apoptotic process GO:0051402 142 0.786
sensory system development GO:0048880 3 0.784
Zebrafish
metencephalon development GO:0022037 89 0.780
positive regulation of cell development GO:0010720 237 0.779
asymmetric neuroblast division GO:0055059 1 0.778
carboxylic acid transport GO:0046942 100 0.775
cerebral cortex development GO:0021987 86 0.770
Mouse
regulation of ras gtpase activity GO:0032318 88 0.765
Mouse
lateral line system development GO:0048925 1 0.764
Zebrafish
positive regulation of ras protein signal transduction GO:0046579 13 0.755
formation of organ boundary GO:0010160 1 0.754
mesenchymal cell development GO:0014031 93 0.749
Zebrafish Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.746
ameboidal type cell migration GO:0001667 128 0.745
Zebrafish Mouse Fly
formation of anatomical boundary GO:0048859 6 0.744
positive regulation of neuron projection regeneration GO:0070572 2 0.740
neural crest cell development GO:0014032 48 0.738
Zebrafish Mouse
regulation of synaptic plasticity GO:0048167 87 0.731
positive regulation of growth GO:0045927 104 0.731
Mouse
learning or memory GO:0007611 148 0.725
Fly
glutamate secretion GO:0014047 8 0.724
positive regulation of gtp catabolic process GO:0033126 85 0.724
Mouse
positive regulation of neuron projection development GO:0010976 79 0.723
olfactory bulb interneuron differentiation GO:0021889 12 0.722
Mouse
regulation of extent of cell growth GO:0061387 52 0.719
neuron recognition GO:0008038 25 0.719
Zebrafish
dendrite development GO:0016358 115 0.714
motor neuron axon guidance GO:0008045 26 0.712
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.707
chemotaxis GO:0006935 247 0.706
Mouse
long term memory GO:0007616 15 0.703
regulation of cardiac muscle tissue development GO:0055024 31 0.701
Mouse
negative regulation of neuroblast proliferation GO:0007406 7 0.691
circulatory system process GO:0003013 197 0.684
Fly
regulation of astrocyte differentiation GO:0048710 20 0.684
erbb signaling pathway GO:0038127 32 0.679
Mouse Rat
regulation of neuron death GO:1901214 134 0.676
ribonucleoside metabolic process GO:0009119 245 0.675
Mouse
neuron death GO:0070997 154 0.674
glial cell development GO:0021782 54 0.666
Zebrafish
camera type eye development GO:0043010 266 0.657
axon ensheathment GO:0008366 76 0.656
Zebrafish Mouse
dicarboxylic acid transport GO:0006835 29 0.655
ureteric bud development GO:0001657 94 0.655
apoptotic signaling pathway GO:0097190 306 0.653
Human Fly
endocardial cell differentiation GO:0060956 4 0.652
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.652
Mouse Rat
neurotransmitter transport GO:0006836 76 0.652
t cell proliferation GO:0042098 120 0.651
Mouse
myelination in peripheral nervous system GO:0022011 19 0.650
regulation of calcium ion transport into cytosol GO:0010522 31 0.649
neuron maturation GO:0042551 29 0.649
neuroblast proliferation GO:0007405 49 0.648
negative regulation of epithelial cell proliferation GO:0050680 64 0.645
pons development GO:0021548 13 0.644
oculomotor nerve morphogenesis GO:0021622 2 0.639
regulation of glial cell differentiation GO:0045685 41 0.636
regulation of neuron apoptotic process GO:0043523 122 0.635
brain derived neurotrophic factor receptor signaling pathway GO:0031547 3 0.633
negative regulation of nervous system development GO:0051961 156 0.630
regulation of ion homeostasis GO:2000021 64 0.625
establishment or maintenance of neuroblast polarity GO:0045196 1 0.621
ureteric bud morphogenesis GO:0060675 62 0.616
hindbrain development GO:0030902 128 0.615
mechanoreceptor differentiation GO:0042490 67 0.599
neurotrophin signaling pathway GO:0038179 12 0.593
negative regulation of t cell activation GO:0050868 65 0.591
Mouse
stem cell maintenance GO:0019827 130 0.588
Fly
ras protein signal transduction GO:0007265 77 0.587
trabecula morphogenesis GO:0061383 40 0.585
retinal cell programmed cell death GO:0046666 8 0.584
Fly
cardiac muscle cell differentiation GO:0055007 69 0.583
small gtpase mediated signal transduction GO:0007264 97 0.579
response to ethanol GO:0045471 18 0.577
Fly
positive regulation of cell growth GO:0030307 33 0.575
regulation of map kinase activity GO:0043405 120 0.575
neuron neuron synaptic transmission GO:0007270 69 0.571
renal system development GO:0072001 225 0.568
Fly
peptidyl amino acid modification GO:0018193 336 0.568
Human Mouse
establishment of neuroblast polarity GO:0045200 1 0.566
cell type specific apoptotic process GO:0097285 268 0.565
mesenchyme development GO:0060485 152 0.562
forebrain generation of neurons GO:0021872 63 0.561
Mouse
medulla oblongata development GO:0021550 3 0.559
mapk cascade GO:0000165 281 0.559
positive regulation of protein phosphorylation GO:0001934 242 0.558
Human Mouse
innervation GO:0060384 22 0.558
positive regulation of heart growth GO:0060421 18 0.555
Mouse
negative regulation of neuron death GO:1901215 98 0.551
regulation of organ morphogenesis GO:2000027 144 0.548
Fly
cerebral cortex cell migration GO:0021795 44 0.547
Mouse
positive regulation of protein modification process GO:0031401 299 0.545
Human Mouse
wnt signaling pathway GO:0016055 188 0.543
regulation of synaptic transmission gabaergic GO:0032228 17 0.542
muscle cell differentiation GO:0042692 261 0.541
amino acid transport GO:0006865 61 0.539
regulation of stem cell proliferation GO:0072091 78 0.535
positive regulation of mapk cascade GO:0043410 170 0.528
embryonic organ morphogenesis GO:0048562 276 0.526
cellular response to lipid GO:0071396 145 0.524
cellular response to nerve growth factor stimulus GO:1990090 3 0.523
positive regulation of rho gtpase activity GO:0032321 41 0.523
Mouse
transmission of nerve impulse GO:0019226 76 0.522
Zebrafish Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.520
Mouse
regulation of protein kinase activity GO:0045859 232 0.520
Human
cerebellum morphogenesis GO:0021587 42 0.518
g1 s transition of mitotic cell cycle GO:0000082 57 0.516
Fly
purine ribonucleotide catabolic process GO:0009154 208 0.516
Mouse
trochlear nerve development GO:0021558 3 0.507
regulation of gliogenesis GO:0014013 50 0.502
oocyte construction GO:0007308 2 0.500
Fly
fibroblast proliferation GO:0048144 35 0.498
Mouse
stem cell proliferation GO:0072089 117 0.493
striated muscle tissue development GO:0014706 293 0.490
Mouse Rat
heart trabecula formation GO:0060347 14 0.490
male sex differentiation GO:0046661 109 0.490
Worm
learning GO:0007612 98 0.489
Fly
hindbrain morphogenesis GO:0021575 46 0.488
bmp signaling pathway GO:0030509 93 0.484
adult behavior GO:0030534 135 0.484
Fly
regulation of apoptotic signaling pathway GO:2001233 197 0.483
Fly
cell migration in hindbrain GO:0021535 16 0.483
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.479
positive regulation of ras gtpase activity GO:0032320 65 0.478
Mouse
cardiocyte differentiation GO:0035051 87 0.477
lactation GO:0007595 25 0.474
Mouse
regulation of heart growth GO:0060420 31 0.472
Mouse
peptidyl tyrosine modification GO:0018212 145 0.472
Human Mouse
negative regulation of anoikis GO:2000811 2 0.467
forebrain development GO:0030900 302 0.466
Mouse
negative regulation of ossification GO:0030279 49 0.464
divalent metal ion transport GO:0070838 172 0.462
regulation of erk1 and erk2 cascade GO:0070372 71 0.458
regulation of neurotransmitter transport GO:0051588 35 0.457
calcium ion transport into cytosol GO:0060402 48 0.456
wound healing GO:0042060 157 0.456
Zebrafish Mouse Fly
rac protein signal transduction GO:0016601 13 0.455
acid secretion GO:0046717 33 0.455
regulation of cell projection organization GO:0031344 206 0.454
regeneration GO:0031099 38 0.454
Zebrafish Mouse
regulation of neuroblast proliferation GO:1902692 27 0.453
axonal fasciculation GO:0007413 15 0.453
Zebrafish
cell differentiation in hindbrain GO:0021533 24 0.452
negative regulation of neuron differentiation GO:0045665 101 0.452
sensory organ boundary specification GO:0008052 1 0.451
regulation of cellular amino acid metabolic process GO:0006521 5 0.451
noradrenergic neuron differentiation GO:0003357 6 0.451
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.442
Human Mouse
oligodendrocyte cell fate commitment GO:0021779 5 0.442
rho protein signal transduction GO:0007266 32 0.441
negative regulation of t cell proliferation GO:0042130 38 0.437
Mouse
pigment metabolic process GO:0042440 32 0.435
mesonephric tubule development GO:0072164 94 0.433
negative regulation of lymphocyte proliferation GO:0050672 45 0.432
Mouse
embryonic placenta development GO:0001892 98 0.430
Mouse
regulation of hippo signaling GO:0035330 1 0.428
t cell activation GO:0042110 289 0.427
Mouse
single organismal cell cell adhesion GO:0016337 131 0.423
Fly
negative regulation of neuron apoptotic process GO:0043524 92 0.421
neurotransmitter secretion GO:0007269 62 0.418
skeletal muscle cell differentiation GO:0035914 66 0.417
forebrain neuron differentiation GO:0021879 52 0.416
Mouse
detection of external stimulus GO:0009581 61 0.414
release of sequestered calcium ion into cytosol GO:0051209 42 0.414
glial cell fate specification GO:0021780 5 0.408
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.406
organic anion transport GO:0015711 137 0.404
ribonucleoside triphosphate catabolic process GO:0009203 199 0.404
Mouse
neuronal action potential GO:0019228 54 0.402
Zebrafish Mouse
cell maturation GO:0048469 127 0.402
Fly
positive regulation of cell projection organization GO:0031346 95 0.401
oocyte differentiation GO:0009994 35 0.401
Fly
embryonic genitalia morphogenesis GO:0030538 4 0.397
regulation of gtp catabolic process GO:0033124 113 0.395
Mouse
tissue regeneration GO:0042246 22 0.395
Zebrafish Mouse
oculomotor nerve development GO:0021557 4 0.394
pallium development GO:0021543 120 0.393
Mouse
negative regulation of glial cell differentiation GO:0045686 21 0.393
rhombomere morphogenesis GO:0021593 2 0.392
ribonucleotide catabolic process GO:0009261 208 0.392
Mouse
negative regulation of cell development GO:0010721 169 0.388
Fly
positive regulation of nucleoside metabolic process GO:0045979 91 0.387
Mouse
regulation of postsynaptic membrane potential GO:0060078 48 0.384
forebrain cell migration GO:0021885 58 0.383
Mouse
purine containing compound catabolic process GO:0072523 213 0.381
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 95 0.380
regulation of neurotransmitter levels GO:0001505 87 0.377
regulation of t cell differentiation GO:0045580 83 0.377
Mouse
multicellular organismal response to stress GO:0033555 62 0.375
trigeminal nerve development GO:0021559 10 0.375
hepaticobiliary system development GO:0061008 67 0.374
cytosolic calcium ion transport GO:0060401 48 0.373
response to amino acid GO:0043200 37 0.373
Mouse
negative regulation of homeostatic process GO:0032845 71 0.370
prenylation GO:0097354 3 0.369
regulation of mesenchymal cell proliferation GO:0010464 37 0.368
central nervous system neuron differentiation GO:0021953 162 0.368
Mouse
regulation of neurotransmitter secretion GO:0046928 29 0.365
regulation of stat protein import into nucleus GO:2000364 2 0.363
Mouse
positive regulation of map kinase activity GO:0043406 84 0.363
cartilage development GO:0051216 140 0.362
peptidyl serine phosphorylation GO:0018105 74 0.360
smoothened signaling pathway GO:0007224 105 0.359
cardiac endothelial cell differentiation GO:0003348 4 0.359
regulation of wnt signaling pathway GO:0030111 123 0.357
regulation of cytoplasmic transport GO:1903649 112 0.356
Mouse
negative regulation of wnt signaling pathway GO:0030178 73 0.355
negative regulation of lymphocyte activation GO:0051250 91 0.352
Mouse
telencephalon development GO:0021537 186 0.351
Mouse
cerebellar cortex formation GO:0021697 22 0.349
positive regulation of kinase activity GO:0033674 155 0.345
Human
response to nerve growth factor GO:1990089 3 0.345
regulation of cellular catabolic process GO:0031329 242 0.344
Mouse
regulation of transcription from rna polymerase i promoter GO:0006356 6 0.342
embryonic epithelial tube formation GO:0001838 130 0.341
mesoderm formation GO:0001707 62 0.340
regulation of cellular ketone metabolic process GO:0010565 66 0.339
developmental cell growth GO:0048588 84 0.338
axon regeneration GO:0031103 12 0.336
single organism cell adhesion GO:0098602 156 0.336
Fly
purine nucleotide metabolic process GO:0006163 302 0.334
Mouse
hypothalamus development GO:0021854 16 0.332
regulation of muscle cell apoptotic process GO:0010660 17 0.331
negative regulation of apoptotic signaling pathway GO:2001234 104 0.331
Fly
regulation of cell motility GO:2000145 236 0.330
Mouse
organophosphate catabolic process GO:0046434 232 0.330
Mouse
neuromuscular synaptic transmission GO:0007274 16 0.327
neural crest cell differentiation GO:0014033 54 0.326
Zebrafish Mouse
negative regulation of immature t cell proliferation GO:0033087 3 0.324
Mouse
blood circulation GO:0008015 195 0.322
formation of radial glial scaffolds GO:0021943 4 0.322
oogenesis GO:0048477 56 0.320
Fly
protein kinase b signaling GO:0043491 74 0.319
regulation of canonical wnt signaling pathway GO:0060828 82 0.316
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.314
cation transport GO:0006812 399 0.313
positive regulation of neuron apoptotic process GO:0043525 25 0.310
adult locomotory behavior GO:0008344 91 0.310
regulation of cell adhesion GO:0030155 154 0.308
Human
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.305
negative regulation of glial cell proliferation GO:0060253 4 0.304
ureter morphogenesis GO:0072197 4 0.303
positive regulation of protein kinase b signaling GO:0051897 32 0.302
sertoli cell differentiation GO:0060008 18 0.302
epidermis development GO:0008544 187 0.302
Mouse
morphogenesis of a branching structure GO:0001763 203 0.302
calcium mediated signaling using intracellular calcium source GO:0035584 3 0.301
regulation of protein tyrosine kinase activity GO:0061097 17 0.300
Human
positive regulation of cell migration GO:0030335 109 0.296
nucleoside triphosphate metabolic process GO:0009141 230 0.296
Mouse
developmental maturation GO:0021700 193 0.290
Fly
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.290
pituitary gland development GO:0021983 38 0.288
nucleoside phosphate metabolic process GO:0006753 338 0.288
Mouse
positive regulation of programmed cell death GO:0043068 218 0.285
erk1 and erk2 cascade GO:0070371 77 0.285
muscle tissue development GO:0060537 308 0.285
Mouse Rat
inositol lipid mediated signaling GO:0048017 41 0.285
Human
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.283
development of primary sexual characteristics GO:0045137 143 0.282
Fly
glycosyl compound metabolic process GO:1901657 246 0.282
Mouse
eye photoreceptor cell differentiation GO:0001754 41 0.281
Fly
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.279
olfactory lobe development GO:0021988 32 0.279
Mouse
brain segmentation GO:0035284 3 0.278
ribonucleoside catabolic process GO:0042454 206 0.277
Mouse
skeletal muscle organ development GO:0060538 163 0.277
Rat
telencephalon cell migration GO:0022029 55 0.275
Mouse
ribose phosphate metabolic process GO:0019693 291 0.275
Mouse
central nervous system neuron axonogenesis GO:0021955 28 0.272
cognition GO:0050890 149 0.272
Fly
negative regulation of astrocyte differentiation GO:0048712 10 0.271
response to alcohol GO:0097305 48 0.267
Fly
neural tube formation GO:0001841 108 0.265
oligodendrocyte cell fate specification GO:0021778 5 0.264
regulation of ras protein signal transduction GO:0046578 114 0.264
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.262
Fly
cerebellum development GO:0021549 77 0.261
neural crest cell migration GO:0001755 32 0.261
Zebrafish Mouse
positive regulation of nucleotide catabolic process GO:0030813 88 0.259
Mouse
locomotory behavior GO:0007626 195 0.259
rhythmic process GO:0048511 174 0.257
Rat
regulation of lymphocyte proliferation GO:0050670 117 0.257
Mouse
response to steroid hormone GO:0048545 56 0.257
regulation of protein stability GO:0031647 52 0.257
regulation of establishment of protein localization GO:0070201 181 0.257
Mouse
purine nucleotide catabolic process GO:0006195 211 0.256
Mouse
lymphocyte differentiation GO:0030098 242 0.256
Mouse
spermatogenesis GO:0007283 284 0.255
sequestering of calcium ion GO:0051208 18 0.255
nucleotide metabolic process GO:0009117 332 0.255
Mouse
regulation of anatomical structure size GO:0090066 178 0.253
response to drug GO:0042493 75 0.253
Rat
mesenchymal cell differentiation GO:0048762 107 0.252
Zebrafish Mouse
taste bud development GO:0061193 2 0.250
negative regulation of neuron projection development GO:0010977 50 0.250
central nervous system segmentation GO:0035283 3 0.250
preganglionic parasympathetic nervous system development GO:0021783 17 0.249
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.246
Human
cranial nerve formation GO:0021603 4 0.243
skin development GO:0043588 220 0.243
Mouse
maintenance of location GO:0051235 89 0.242
cellular chemical homeostasis GO:0055082 215 0.241
protein catabolic process GO:0030163 221 0.241
negative regulation of ovulation GO:0060280 1 0.239
regulation of striated muscle cell differentiation GO:0051153 81 0.235
developmental growth involved in morphogenesis GO:0060560 138 0.234
amine metabolic process GO:0009308 45 0.232
germ line stem cell maintenance GO:0030718 6 0.232
Fly
epidermal growth factor receptor signaling pathway GO:0007173 28 0.231
Mouse Rat
establishment of planar polarity GO:0001736 28 0.230
Fly
synapse organization GO:0050808 125 0.227
Mouse
regulation of anoikis GO:2000209 2 0.227
posttranscriptional regulation of gene expression GO:0010608 155 0.227
photoreceptor cell differentiation GO:0046530 52 0.226
Fly
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.226
Fly
leukocyte differentiation GO:0002521 342 0.226
Mouse
regulation of rho protein signal transduction GO:0035023 71 0.226
Mouse
stem cell fate specification GO:0048866 3 0.225
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.223
regulation of wound healing GO:0061041 40 0.222
Fly
protein localization to membrane GO:0072657 108 0.222
positive regulation of apoptotic process GO:0043065 217 0.220
regulation of retinal cell programmed cell death GO:0046668 5 0.219
Fly
parasympathetic nervous system development GO:0048486 19 0.217
cellular response to retinoic acid GO:0071300 25 0.217
rhombomere 5 development GO:0021571 4 0.215
locus ceruleus development GO:0021703 1 0.214
cardiac muscle cell proliferation GO:0060038 31 0.214
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.213
positive regulation of hydrolase activity GO:0051345 148 0.213
Mouse
negative regulation of gliogenesis GO:0014014 23 0.213
t cell differentiation in thymus GO:0033077 77 0.212
Mouse
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.212
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.210
regulation of protein kinase b signaling GO:0051896 56 0.209
cardiac chamber development GO:0003205 108 0.209
negative regulation of neural precursor cell proliferation GO:2000178 18 0.206
female gamete generation GO:0007292 74 0.206
Worm Fly
membrane hyperpolarization GO:0060081 21 0.205
epithelial tube formation GO:0072175 130 0.205
transcription from rna polymerase iii promoter GO:0006383 3 0.204
synapse assembly GO:0007416 56 0.204
limbic system development GO:0021761 72 0.204
regulation of intracellular transport GO:0032386 159 0.204
Mouse
genitalia development GO:0048806 37 0.204
Worm
glucose transport GO:0015758 56 0.203
Rat
nephron epithelium morphogenesis GO:0072088 68 0.202
sensory perception GO:0007600 245 0.201
noradrenergic neuron development GO:0003358 3 0.201
segmentation GO:0035282 93 0.198
Fly
memory GO:0007613 58 0.198
purine ribonucleotide metabolic process GO:0009150 290 0.198
Mouse
mammary gland epithelium development GO:0061180 65 0.196
Mouse
regulation of cell activation GO:0050865 289 0.195
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.194
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.194
negative regulation of leukocyte differentiation GO:1902106 51 0.194
Mouse
diencephalon development GO:0021536 63 0.193
heart process GO:0003015 94 0.192
Fly
spinal cord motor neuron differentiation GO:0021522 35 0.192
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.191
Human Mouse
negative regulation of secretion GO:0051048 61 0.191
Human
endocardium development GO:0003157 10 0.190
muscle cell proliferation GO:0033002 52 0.190
Mouse
divalent inorganic cation transport GO:0072511 178 0.189
blood vessel morphogenesis GO:0048514 285 0.187
regulation of organ growth GO:0046620 61 0.186
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.186
regulation of bmp signaling pathway GO:0030510 60 0.184
ventral spinal cord development GO:0021517 48 0.184
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.184
metal ion homeostasis GO:0055065 189 0.184
urogenital system development GO:0001655 261 0.183
Fly
brain morphogenesis GO:0048854 32 0.181
regulation of myotube differentiation GO:0010830 62 0.180
ion transmembrane transport GO:0034220 361 0.178
negative regulation of cell cycle process GO:0010948 69 0.178
Fly
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.176
nucleoside metabolic process GO:0009116 246 0.176
Mouse
response to peptide GO:1901652 136 0.175
Rat
regulation of protein binding GO:0043393 60 0.175
regulation of nucleotide metabolic process GO:0006140 169 0.174
Mouse
regulation of neural precursor cell proliferation GO:2000177 70 0.174
protein prenylation GO:0018342 3 0.174
astrocyte differentiation GO:0048708 43 0.173
nitrogen compound transport GO:0071705 271 0.173
positive regulation of striated muscle tissue development GO:0045844 31 0.173
Mouse
cation homeostasis GO:0055080 212 0.172
positive regulation of behavior GO:0048520 40 0.172
macromolecular complex disassembly GO:0032984 43 0.171
organ growth GO:0035265 117 0.170
Mouse
regulation of rac protein signal transduction GO:0035020 19 0.169
regulation of tyrosine phosphorylation of stat protein GO:0042509 20 0.169
Mouse
mesonephric epithelium development GO:0072163 94 0.169
positive regulation of tyrosine phosphorylation of stat5 protein GO:0042523 6 0.167
Mouse
neuron migration GO:0001764 122 0.166
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.166
Fly
ribonucleotide metabolic process GO:0009259 291 0.166
Mouse
positive regulation of gtpase activity GO:0043547 85 0.166
Mouse
response to inactivity GO:0014854 4 0.165
male genitalia development GO:0030539 20 0.165
Worm
nucleoside catabolic process GO:0009164 206 0.164
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.163
purine nucleoside triphosphate catabolic process GO:0009146 203 0.163
Mouse
cellular lipid metabolic process GO:0044255 323 0.163
negative regulation of mitotic cell cycle GO:0045930 58 0.162
Fly

Erbb3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.830
disease of cellular proliferation DOID:14566 0 0.830
organ system cancer DOID:0050686 0 0.830
disease of anatomical entity DOID:7 0 0.790
nervous system disease DOID:863 0 0.790
heart disease DOID:114 0 0.528
cardiovascular system disease DOID:1287 0 0.528
gastrointestinal system cancer DOID:3119 0 0.358
sensory system disease DOID:0050155 0 0.244
eye and adnexa disease DOID:1492 0 0.244
gastrointestinal system disease DOID:77 0 0.232
intestinal disease DOID:5295 0 0.232
stomach cancer DOID:10534 0 0.215
retinal disease DOID:5679 0 0.213
retinal degeneration DOID:8466 0 0.213
eye disease DOID:5614 0 0.213
neuromuscular disease DOID:440 0 0.166
neuropathy DOID:870 0 0.166