|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.913
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.731
|
Human |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.704
|
Fly |
|
|
ear development
|
GO:0043583 |
200 |
0.693
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.648
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.602
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.599
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.582
|
|
|
|
nerve development
|
GO:0021675 |
67 |
0.564
|
Mouse |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.548
|
|
|
|
limbic system development
|
GO:0021761 |
72 |
0.531
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.530
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.522
|
Human |
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.518
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.505
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.502
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.496
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.476
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.468
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.466
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.465
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.464
|
Mouse |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.444
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.429
|
Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.426
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.426
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.423
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.403
|
Human |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.386
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.375
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.374
|
Mouse |
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.369
|
Worm |
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.349
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.332
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.328
|
Mouse |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.326
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.323
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.311
|
Fly |
|
|
cognition
|
GO:0050890 |
149 |
0.310
|
Fly |
|
|
angiogenesis
|
GO:0001525 |
201 |
0.305
|
|
|
|
thyroid stimulating hormone secreting cell differentiation
|
GO:0060129 |
4 |
0.301
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.294
|
Rat |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.279
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.279
|
Fly |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.276
|
Mouse |
|
|
gland development
|
GO:0048732 |
330 |
0.273
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.271
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.266
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.257
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.255
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.254
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.252
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.252
|
Mouse |
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.250
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.247
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.245
|
Mouse |
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.242
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.240
|
Rat |
|
|
positive regulation of cardiac muscle cell proliferation
|
GO:0060045 |
15 |
0.240
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.239
|
Mouse |
|
|
positive regulation of striated muscle tissue development
|
GO:0045844 |
31 |
0.237
|
|
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.237
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.235
|
|
|
|
cardiac muscle tissue morphogenesis
|
GO:0055008 |
44 |
0.233
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.231
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.229
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
83 |
0.226
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.226
|
Mouse |
|
|
regionalization
|
GO:0003002 |
337 |
0.225
|
Fly |
|
|
atrial ventricular junction remodeling
|
GO:0003294 |
2 |
0.225
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.220
|
Mouse |
|
|
av node cell to bundle of his cell communication
|
GO:0086067 |
2 |
0.218
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.215
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.215
|
Fly |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.213
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.213
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.213
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.212
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.212
|
Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.211
|
Fly |
|
|
segmentation
|
GO:0035282 |
93 |
0.210
|
Fly |
|
|
associative learning
|
GO:0008306 |
61 |
0.208
|
Fly |
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.207
|
Mouse |
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.205
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.199
|
Mouse |
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.198
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.196
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.194
|
|
|
|
neural crest cell development
|
GO:0014032 |
48 |
0.192
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.190
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.187
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.187
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.186
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.185
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
27 |
0.183
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
31 |
0.182
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.174
|
Human |
|
|
heart process
|
GO:0003015 |
94 |
0.173
|
Fly |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.172
|
Mouse Rat |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.170
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.170
|
Mouse |
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.169
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
23 |
0.167
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.165
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.165
|
Human |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.164
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.163
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.160
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.160
|
|
|
|
central nervous system morphogenesis
|
GO:0021551 |
2 |
0.160
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.160
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
52 |
0.159
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.159
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.156
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.155
|
Rat Fly |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.155
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.155
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.154
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.152
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.150
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.150
|
|
|
|
cerebellum development
|
GO:0021549 |
77 |
0.149
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.149
|
Mouse |
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.149
|
|
|
|
hippocampus development
|
GO:0021766 |
52 |
0.148
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.147
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.146
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.146
|
Mouse |
|
|
branching involved in mammary gland duct morphogenesis
|
GO:0060444 |
27 |
0.145
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.145
|
Human |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.144
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.144
|
|
|
|
regulation of action potential
|
GO:0098900 |
4 |
0.143
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.143
|
Mouse Fly |
|
|
neural tube development
|
GO:0021915 |
160 |
0.142
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.142
|
Mouse |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.142
|
Mouse |
|
|
neural crest cell migration
|
GO:0001755 |
32 |
0.141
|
|
|
|
brain segmentation
|
GO:0035284 |
3 |
0.140
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.138
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.137
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
7 |
0.137
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.137
|
Mouse |
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.137
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.136
|
Fly |
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.136
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.135
|
|
|
|
learning
|
GO:0007612 |
98 |
0.135
|
Fly |
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.134
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.134
|
Mouse |
|
|
axon guidance
|
GO:0007411 |
141 |
0.133
|
Mouse |
|
|
negative regulation of neuron projection development
|
GO:0010977 |
50 |
0.131
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.130
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.128
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
26 |
0.127
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.127
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.127
|
Rat |
|
|
fertilization
|
GO:0009566 |
127 |
0.127
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.126
|
Fly |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.125
|
|
|
|
olfactory bulb development
|
GO:0021772 |
30 |
0.125
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.125
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
51 |
0.125
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.124
|
Mouse |
|
|
mechanoreceptor differentiation
|
GO:0042490 |
67 |
0.124
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.122
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.121
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.120
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.119
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.118
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.118
|
|
|
|
planar cell polarity pathway involved in cardiac right atrium morphogenesis
|
GO:0061349 |
2 |
0.117
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.117
|
Mouse |
|
|
positive regulation of heart rate by epinephrine norepinephrine
|
GO:0001996 |
4 |
0.116
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.116
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.116
|
|
|
|
canonical wnt signaling pathway involved in regulation of cell proliferation
|
GO:0044340 |
3 |
0.116
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.115
|
Mouse |
|
|
cell maturation
|
GO:0048469 |
127 |
0.113
|
Fly |
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.113
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.113
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.112
|
|
|
|
foramen ovale closure
|
GO:0035922 |
1 |
0.112
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.112
|
Mouse |
|
|
muscle tissue morphogenesis
|
GO:0060415 |
53 |
0.111
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.110
|
Human |
|
|
ventricular septum development
|
GO:0003281 |
42 |
0.109
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.109
|
Fly |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.109
|
Mouse |
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.108
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.108
|
Mouse |
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.108
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.108
|
Mouse |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.107
|
Fly |
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.107
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.107
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.106
|
Mouse |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.106
|
Fly |
|
|
sa node cell action potential
|
GO:0086015 |
4 |
0.106
|
|
|
|
positive regulation of cardiac muscle tissue development
|
GO:0055025 |
19 |
0.105
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.105
|
Mouse |
|
|
planar cell polarity pathway involved in outflow tract morphogenesis
|
GO:0061347 |
2 |
0.104
|
|
|
|
positive regulation of organ growth
|
GO:0046622 |
29 |
0.104
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.104
|
Mouse |
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.103
|
Mouse |
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.103
|
|
|
|
positive regulation of muscle tissue development
|
GO:1901863 |
32 |
0.102
|
|
|
|
axis elongation involved in somitogenesis
|
GO:0090245 |
4 |
0.101
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.101
|
Mouse |
|
|
protein targeting
|
GO:0006605 |
143 |
0.101
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
56 |
0.100
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.099
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.098
|
Mouse Rat Fly |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.098
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.098
|
Mouse |
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.098
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.097
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.097
|
Mouse Rat |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.097
|
Mouse |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.097
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.097
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.096
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.096
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.096
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.096
|
Mouse Fly |
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.096
|
Mouse |
|
|
cardiac ventricle morphogenesis
|
GO:0003208 |
50 |
0.096
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.096
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.096
|
Mouse |
|
|
cardiac muscle tissue growth
|
GO:0055017 |
37 |
0.095
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.095
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.095
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.094
|
|
|
|
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
|
GO:0061350 |
2 |
0.093
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.093
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.092
|
|
|
|
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure
|
GO:0002025 |
3 |
0.090
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.090
|
|
|
|
sa node cell to atrial cardiac muscle cell signalling
|
GO:0086018 |
4 |
0.090
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.090
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.090
|
Mouse |
|
|
positive regulation of cardiac muscle tissue growth
|
GO:0055023 |
15 |
0.090
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.090
|
|
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.089
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.089
|
Mouse |
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.089
|
Mouse |
|
|
establishment of planar polarity involved in neural tube closure
|
GO:0090177 |
15 |
0.089
|
|
|
|
cochlea development
|
GO:0090102 |
35 |
0.088
|
|
|
|
wnt signaling pathway involved in forebrain neuroblast division
|
GO:0021874 |
2 |
0.088
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.087
|
Fly |
|
|
organelle fission
|
GO:0048285 |
170 |
0.087
|
Human |
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.086
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.086
|
Mouse |
|
|
central nervous system segmentation
|
GO:0035283 |
3 |
0.086
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.086
|
Fly |
|
|
ventricular cardiac muscle cell action potential
|
GO:0086005 |
4 |
0.085
|
|
|
|
diencephalon development
|
GO:0021536 |
63 |
0.085
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.085
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.085
|
|
|
|
cell fate specification
|
GO:0001708 |
72 |
0.085
|
Fly |
|
|
oocyte construction
|
GO:0007308 |
2 |
0.084
|
Fly |
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.084
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.084
|
Mouse |
|
|
milk ejection
|
GO:0060156 |
1 |
0.083
|
|
|
|
cranial nerve development
|
GO:0021545 |
41 |
0.083
|
Mouse |
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.083
|
|
|
|
positive regulation of heart growth
|
GO:0060421 |
18 |
0.082
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.082
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.082
|
Mouse |
|
|
histamine induced gastric acid secretion
|
GO:0001697 |
1 |
0.081
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.081
|
|
|
|
wnt signaling pathway calcium modulating pathway
|
GO:0007223 |
2 |
0.081
|
|
|
|
calcium ion dependent exocytosis
|
GO:0017156 |
35 |
0.081
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.080
|
Fly |
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.080
|
|
|
|
neural crest cell differentiation
|
GO:0014033 |
54 |
0.080
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.080
|
Mouse |
|
|
organ growth
|
GO:0035265 |
117 |
0.080
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.080
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.079
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.079
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.078
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.078
|
Fly |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.078
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.077
|
Mouse |
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.077
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.077
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
61 |
0.077
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.077
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.077
|
Fly |
|
|
planar cell polarity pathway involved in pericardium morphogenesis
|
GO:0061354 |
2 |
0.077
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.077
|
Fly |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.076
|
Mouse |
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.076
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.075
|
|
|
|
olfactory bulb interneuron differentiation
|
GO:0021889 |
12 |
0.075
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.075
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.075
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.075
|
|
|
|
mammary gland duct morphogenesis
|
GO:0060603 |
38 |
0.074
|
|
|
|
positive regulation of the force of heart contraction by chemical signal
|
GO:0003099 |
3 |
0.074
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
41 |
0.074
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.074
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.074
|
Fly |
|
|
neuron migration
|
GO:0001764 |
122 |
0.074
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.074
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.074
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.074
|
Mouse |
|
|
mammary gland morphogenesis
|
GO:0060443 |
54 |
0.074
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.073
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
63 |
0.072
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.072
|
Mouse |
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.072
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.072
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
27 |
0.071
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.071
|
Mouse |
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.070
|
Mouse |
|
|
ventricular cardiac myofibril assembly
|
GO:0055005 |
3 |
0.070
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.069
|
Mouse |
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.069
|
|
|
|
sensory system development
|
GO:0048880 |
3 |
0.069
|
|
|
|
forebrain neuron development
|
GO:0021884 |
30 |
0.068
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.068
|
Mouse |
|
|
regulation of establishment of planar polarity
|
GO:0090175 |
28 |
0.067
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.067
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.067
|
Fly |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.067
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.066
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.066
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.065
|
Human Mouse |
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.065
|
Mouse |
|
|
positive regulation of the force of heart contraction by epinephrine norepinephrine
|
GO:0001997 |
3 |
0.065
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.065
|
Human Mouse |
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.065
|
Fly |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.064
|
Mouse |
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.064
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.064
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.064
|
Mouse |
|
|
female gamete generation
|
GO:0007292 |
74 |
0.064
|
Worm Fly |
|
|
heart contraction
|
GO:0060047 |
93 |
0.063
|
|
|
|
olfactory lobe development
|
GO:0021988 |
32 |
0.063
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.063
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.063
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.062
|
Fly |
|
|
central nervous system neuron development
|
GO:0021954 |
67 |
0.062
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.062
|
Mouse |
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
26 |
0.062
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.062
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.062
|
|
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
66 |
0.062
|
|
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
59 |
0.062
|
|
|
|
testosterone biosynthetic process
|
GO:0061370 |
2 |
0.061
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.061
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.061
|
Mouse |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.061
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.061
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.061
|
|
|
|
positive regulation of carbohydrate metabolic process
|
GO:0045913 |
30 |
0.060
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
10 |
0.060
|
|
|
|
negative regulation of hormone metabolic process
|
GO:0032351 |
4 |
0.060
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.060
|
Mouse |
|
|
oviduct development
|
GO:0060066 |
3 |
0.060
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.060
|
|
|
|
fear response
|
GO:0042596 |
33 |
0.060
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.060
|
|
|
|
embryonic genitalia morphogenesis
|
GO:0030538 |
4 |
0.060
|
|
|
|
lateral line system development
|
GO:0048925 |
1 |
0.059
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.059
|
|
|
|
axonal fasciculation
|
GO:0007413 |
15 |
0.059
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.059
|
|
|
|
pituitary gland development
|
GO:0021983 |
38 |
0.058
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.058
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.058
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.058
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.058
|
Fly |
|
|
positive regulation of voltage gated calcium channel activity
|
GO:1901387 |
2 |
0.058
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.058
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.058
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.057
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.057
|
|
|
|
operant conditioning
|
GO:0035106 |
2 |
0.057
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.057
|
Fly |
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.057
|
|
|
|
planar cell polarity pathway involved in ventricular septum morphogenesis
|
GO:0061348 |
2 |
0.057
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.057
|
Mouse |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.057
|
Mouse |
|
|
cell communication by electrical coupling involved in cardiac conduction
|
GO:0086064 |
2 |
0.057
|
|
|
|
cardiac right atrium morphogenesis
|
GO:0003213 |
3 |
0.057
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.056
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.056
|
|
|
|
negative regulation of embryonic development
|
GO:0045992 |
22 |
0.056
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.056
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.056
|
Rat |
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.056
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.056
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.055
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.055
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.055
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.055
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
65 |
0.055
|
|
|
|
regulation of antimicrobial peptide biosynthetic process
|
GO:0002805 |
1 |
0.055
|
|
|
|
positive regulation of inositol phosphate biosynthetic process
|
GO:0060732 |
2 |
0.054
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.054
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.054
|
Mouse |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.054
|
Mouse |
|
|
cytokine production
|
GO:0001816 |
319 |
0.054
|
|
|
|
bone mineralization
|
GO:0030282 |
54 |
0.054
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
30 |
0.054
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.054
|
Fly |
|
|
schwann cell development
|
GO:0014044 |
22 |
0.054
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.054
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.054
|
Fly |
|
|
hindbrain morphogenesis
|
GO:0021575 |
46 |
0.054
|
|
|
|
negative regulation of behavior
|
GO:0048521 |
14 |
0.053
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.053
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.053
|
Mouse |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.053
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.053
|
Mouse |
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.053
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.053
|
Mouse |
|
|
positive regulation of cell growth
|
GO:0030307 |
33 |
0.052
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.052
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.052
|
|
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
2 |
0.052
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.052
|
Mouse |
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.052
|
Mouse |
|
|
planar cell polarity pathway involved in heart morphogenesis
|
GO:0061346 |
3 |
0.052
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.052
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.051
|
|
|
|
regulation of extent of cell growth
|
GO:0061387 |
52 |
0.051
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.051
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
51 |
0.051
|
|
|
|
cardiac septum development
|
GO:0003279 |
59 |
0.051
|
|
|
|
positive regulation of cellular carbohydrate metabolic process
|
GO:0010676 |
29 |
0.051
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.051
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.051
|
Mouse |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.050
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.050
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.050
|
Mouse Fly |
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.050
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.050
|
|
|
|
establishment of neuroblast polarity
|
GO:0045200 |
1 |
0.050
|
|
|
|
regulation of renin secretion into blood stream
|
GO:1900133 |
4 |
0.050
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.049
|
|
|
|
regulation of heart growth
|
GO:0060420 |
31 |
0.049
|
|
|
|
regulation of ventricular cardiac muscle cell membrane depolarization
|
GO:0060373 |
2 |
0.049
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.049
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.049
|
|
|
|
rhombomere 5 development
|
GO:0021571 |
4 |
0.049
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.049
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.049
|
Human |
|
|
somatotropin secreting cell differentiation
|
GO:0060126 |
4 |
0.048
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.048
|
Fly |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.048
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
28 |
0.048
|
Fly |
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.048
|
|
|
|
mesenchymal epithelial cell signaling
|
GO:0060638 |
9 |
0.048
|
|
|
|
polarity specification of proximal distal axis
|
GO:0010085 |
2 |
0.048
|
|
|
|
regulation of high voltage gated calcium channel activity
|
GO:1901841 |
2 |
0.048
|
|
|
|
male gonad development
|
GO:0008584 |
88 |
0.047
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.047
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.047
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.047
|
|
|
|
negative regulation of neuron projection regeneration
|
GO:0070571 |
3 |
0.047
|
|
|
|
cardiac conduction system development
|
GO:0003161 |
12 |
0.047
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.047
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.047
|
Fly |
|
|
regulation of biomineral tissue development
|
GO:0070167 |
33 |
0.046
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.046
|
Fly |
|
|
cerebellum morphogenesis
|
GO:0021587 |
42 |
0.046
|
|
|
|
artery development
|
GO:0060840 |
53 |
0.046
|
|
|
|
phospholipase c activating serotonin receptor signaling pathway
|
GO:0007208 |
1 |
0.046
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.046
|
Mouse |
|
|
regulation of organ growth
|
GO:0046620 |
61 |
0.046
|
|
|
|
trabecula morphogenesis
|
GO:0061383 |
40 |
0.046
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.045
|
Mouse |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.045
|
|
|
|
spemann organizer formation
|
GO:0060061 |
2 |
0.045
|
|
|
|
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation
|
GO:2000081 |
1 |
0.045
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.045
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.045
|
Rat Fly |
|
|
cell division
|
GO:0051301 |
120 |
0.045
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.045
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.045
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.045
|
Human |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.045
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.045
|
|
|
|
ovulation
|
GO:0030728 |
15 |
0.044
|
Worm |
|
|
androgen biosynthetic process
|
GO:0006702 |
4 |
0.044
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.044
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.044
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation
|
GO:0003257 |
3 |
0.044
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
35 |
0.044
|
|
|
|
heart growth
|
GO:0060419 |
45 |
0.044
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.044
|
|
