Mus musculus

15 known processes

Evc2

Ellis van Creveld syndrome 2 homolog (human)

(Aliases: Lbn,limbin,1110017L09Rik)

Evc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
smoothened signaling pathway GO:0007224 105 0.762
regulation of smoothened signaling pathway GO:0008589 58 0.242
developmental growth involved in morphogenesis GO:0060560 138 0.222
endochondral bone growth GO:0003416 19 0.217
positive regulation of smoothened signaling pathway GO:0045880 23 0.203
skeletal system development GO:0001501 356 0.179
organ growth GO:0035265 117 0.149
skeletal system morphogenesis GO:0048705 203 0.144
bone development GO:0060348 120 0.132
endochondral bone morphogenesis GO:0060350 50 0.109
bone morphogenesis GO:0060349 78 0.101
ribonucleoside catabolic process GO:0042454 206 0.086
nucleoside phosphate metabolic process GO:0006753 338 0.077
purine nucleotide catabolic process GO:0006195 211 0.070
organic cyclic compound catabolic process GO:1901361 295 0.068
nucleoside triphosphate metabolic process GO:0009141 230 0.065
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.065
nucleobase containing small molecule metabolic process GO:0055086 352 0.063
organonitrogen compound catabolic process GO:1901565 264 0.061
positive regulation of cell development GO:0010720 237 0.060
regulation of cellular amino acid metabolic process GO:0006521 5 0.056
ribonucleotide metabolic process GO:0009259 291 0.055
regulation of cellular ketone metabolic process GO:0010565 66 0.053
purine containing compound metabolic process GO:0072521 311 0.052
carbohydrate derivative catabolic process GO:1901136 231 0.051
purine nucleoside triphosphate metabolic process GO:0009144 226 0.050
purine ribonucleotide catabolic process GO:0009154 208 0.049
purine nucleotide metabolic process GO:0006163 302 0.049
actin cytoskeleton organization GO:0030036 220 0.049
transmission of nerve impulse GO:0019226 76 0.048
nucleoside phosphate catabolic process GO:1901292 222 0.047
glycosyl compound metabolic process GO:1901657 246 0.047
cation transmembrane transport GO:0098655 266 0.046
cellular nitrogen compound catabolic process GO:0044270 280 0.046
nucleoside metabolic process GO:0009116 246 0.046
regulation of membrane potential GO:0042391 192 0.045
purine ribonucleoside metabolic process GO:0046128 241 0.044
cellular amino acid metabolic process GO:0006520 103 0.042
ribonucleoside triphosphate metabolic process GO:0009199 220 0.042
nucleoside triphosphate catabolic process GO:0009143 205 0.042
muscle cell differentiation GO:0042692 261 0.041
regulation of hydrolase activity GO:0051336 246 0.040
chemotaxis GO:0006935 247 0.039
positive regulation of protein kinase activity GO:0045860 144 0.039
cellular amine metabolic process GO:0044106 44 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.037
regulation of nucleoside metabolic process GO:0009118 130 0.037
purine nucleoside metabolic process GO:0042278 241 0.037
amine metabolic process GO:0009308 45 0.036
cellular ketone metabolic process GO:0042180 84 0.035
heterocycle catabolic process GO:0046700 280 0.035
guanosine containing compound catabolic process GO:1901069 144 0.035
guanosine containing compound metabolic process GO:1901068 144 0.034
wnt signaling pathway GO:0016055 188 0.034
nucleotide metabolic process GO:0009117 332 0.034
regulation of nucleotide metabolic process GO:0006140 169 0.034
cation transport GO:0006812 399 0.034
ribonucleoside metabolic process GO:0009119 245 0.033
nucleoside catabolic process GO:0009164 206 0.033
purine containing compound catabolic process GO:0072523 213 0.033
purine nucleoside catabolic process GO:0006152 205 0.032
regulation of anatomical structure size GO:0090066 178 0.032
small gtpase mediated signal transduction GO:0007264 97 0.031
purine ribonucleoside catabolic process GO:0046130 205 0.031
morphogenesis of a branching structure GO:0001763 203 0.030
regulation of protein localization GO:0032880 231 0.030
aromatic compound catabolic process GO:0019439 286 0.030
rhythmic process GO:0048511 174 0.029
purine nucleoside triphosphate catabolic process GO:0009146 203 0.029
multicellular organism growth GO:0035264 161 0.029
regulation of system process GO:0044057 200 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.029
action potential GO:0001508 78 0.028
nucleotide catabolic process GO:0009166 217 0.028
regulation of cellular amine metabolic process GO:0033238 20 0.028
ribonucleoside triphosphate catabolic process GO:0009203 199 0.028
membrane organization GO:0061024 245 0.028
intracellular protein transport GO:0006886 204 0.027
appendage development GO:0048736 166 0.026
positive regulation of nervous system development GO:0051962 221 0.026
neural tube development GO:0021915 160 0.026
muscle tissue development GO:0060537 308 0.026
ribose phosphate metabolic process GO:0019693 291 0.025
morphogenesis of embryonic epithelium GO:0016331 159 0.025
male gamete generation GO:0048232 285 0.025
gtp catabolic process GO:0006184 143 0.025
regulation of organelle organization GO:0033043 289 0.024
hematopoietic progenitor cell differentiation GO:0002244 143 0.024
urogenital system development GO:0001655 261 0.024
positive regulation of hydrolase activity GO:0051345 148 0.024
organophosphate catabolic process GO:0046434 232 0.023
positive regulation of cellular catabolic process GO:0031331 148 0.023
regulation of purine nucleotide metabolic process GO:1900542 169 0.023
regulation of gtp catabolic process GO:0033124 113 0.023
cell recognition GO:0008037 83 0.023
regulation of nucleotide catabolic process GO:0030811 122 0.022
regulation of mapk cascade GO:0043408 248 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
positive regulation of growth GO:0045927 104 0.022
ossification GO:0001503 216 0.022
synaptic transmission GO:0007268 329 0.022
gland development GO:0048732 330 0.022
glycosyl compound catabolic process GO:1901658 206 0.021
forebrain development GO:0030900 302 0.021
lateral inhibition GO:0046331 1 0.021
response to oxidative stress GO:0006979 123 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
sulfur compound metabolic process GO:0006790 100 0.021
cellular lipid metabolic process GO:0044255 323 0.021
positive regulation of protein modification process GO:0031401 299 0.020
locomotory behavior GO:0007626 195 0.020
ras protein signal transduction GO:0007265 77 0.020
dendrite development GO:0016358 115 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
g protein coupled receptor signaling pathway GO:0007186 243 0.020
lymphocyte differentiation GO:0030098 242 0.020
developmental maturation GO:0021700 193 0.020
ribonucleotide catabolic process GO:0009261 208 0.019
epithelial tube formation GO:0072175 130 0.019
regulation of map kinase activity GO:0043405 120 0.019
dna metabolic process GO:0006259 303 0.019
cytoplasmic transport GO:0016482 234 0.019
epithelial cell development GO:0002064 159 0.019
embryonic appendage morphogenesis GO:0035113 126 0.019
inorganic cation transmembrane transport GO:0098662 207 0.019
spermatogenesis GO:0007283 284 0.019
embryonic epithelial tube formation GO:0001838 130 0.019
regulation of cell projection organization GO:0031344 206 0.019
cell maturation GO:0048469 127 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
midgut development GO:0007494 4 0.018
neuron apoptotic process GO:0051402 142 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
branching morphogenesis of an epithelial tube GO:0048754 159 0.018
peptidyl amino acid modification GO:0018193 336 0.018
rho protein signal transduction GO:0007266 32 0.018
regulation of striated muscle cell differentiation GO:0051153 81 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
carbohydrate homeostasis GO:0033500 128 0.018
positive regulation of nucleoside metabolic process GO:0045979 91 0.017
leukocyte differentiation GO:0002521 342 0.017
positive regulation of cell death GO:0010942 224 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
kidney development GO:0001822 213 0.017
central nervous system neuron differentiation GO:0021953 162 0.017
cell substrate adhesion GO:0031589 130 0.017
gtp metabolic process GO:0046039 144 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
regulation of defense response GO:0031347 233 0.017
respiratory system development GO:0060541 190 0.017
immune effector process GO:0002252 321 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
skeletal muscle organ development GO:0060538 163 0.016
protein localization to organelle GO:0033365 185 0.016
positive regulation of mapk cascade GO:0043410 170 0.016
transmembrane transport GO:0055085 412 0.016
positive regulation of neuron differentiation GO:0045666 141 0.016
positive regulation of cell projection organization GO:0031346 95 0.016
cell fate commitment GO:0045165 210 0.016
protein ubiquitination GO:0016567 171 0.016
neuronal action potential GO:0019228 54 0.016
neural tube closure GO:0001843 90 0.016
tube formation GO:0035148 140 0.016
apoptotic signaling pathway GO:0097190 306 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.016
sensory organ morphogenesis GO:0090596 242 0.015
positive regulation of nucleotide catabolic process GO:0030813 88 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.015
positive regulation of gtpase activity GO:0043547 85 0.015
regulation of neuron death GO:1901214 134 0.015
regulation of response to wounding GO:1903034 189 0.015
positive regulation of map kinase activity GO:0043406 84 0.015
gastrulation GO:0007369 116 0.015
cell adhesion GO:0007155 329 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
neuron projection guidance GO:0097485 141 0.015
protein catabolic process GO:0030163 221 0.015
multicellular organismal signaling GO:0035637 91 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
regulation of secretion GO:0051046 274 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.014
morphogenesis of a branching epithelium GO:0061138 193 0.014
negative regulation of cell development GO:0010721 169 0.014
retina development in camera type eye GO:0060041 119 0.014
organelle fission GO:0048285 170 0.014
negative regulation of synapse assembly GO:0051964 3 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
macromolecule catabolic process GO:0009057 281 0.014
spermatid differentiation GO:0048515 115 0.014
myotube differentiation GO:0014902 105 0.014
renal system development GO:0072001 225 0.014
regulation of neuron differentiation GO:0045664 281 0.014
positive regulation of transferase activity GO:0051347 167 0.014
negative regulation of neuron projection regeneration GO:0070571 3 0.014
activation of mapk activity GO:0000187 59 0.014
regulation of cell migration GO:0030334 219 0.014
maintenance of location GO:0051235 89 0.014
neural precursor cell proliferation GO:0061351 121 0.013
interleukin 8 production GO:0032637 4 0.013
regulation of cell size GO:0008361 72 0.013
germ cell development GO:0007281 185 0.013
cellular chemical homeostasis GO:0055082 215 0.013
gonad development GO:0008406 141 0.013
cell type specific apoptotic process GO:0097285 268 0.013
ion transmembrane transport GO:0034220 361 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
response to organonitrogen compound GO:0010243 246 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
multi multicellular organism process GO:0044706 109 0.013
positive regulation of gtp catabolic process GO:0033126 85 0.013
circulatory system process GO:0003013 197 0.013
regulation of ion transport GO:0043269 215 0.013
regulation of interleukin 8 production GO:0032677 3 0.013
regulation of fat cell differentiation GO:0045598 81 0.013
camera type eye development GO:0043010 266 0.012
negative regulation of immune system process GO:0002683 209 0.012
ameboidal type cell migration GO:0001667 128 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
mesoderm development GO:0007498 100 0.012
connective tissue development GO:0061448 179 0.012
positive regulation of defense response GO:0031349 124 0.012
leukocyte migration GO:0050900 124 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
nuclear import GO:0051170 95 0.012
heart morphogenesis GO:0003007 178 0.012
organelle assembly GO:0070925 177 0.012
protein processing GO:0016485 163 0.012
neural tube formation GO:0001841 108 0.012
regulation of cell activation GO:0050865 289 0.012
fatty acid metabolic process GO:0006631 121 0.012
cation homeostasis GO:0055080 212 0.012
divalent inorganic cation transport GO:0072511 178 0.012
protein import into nucleus GO:0006606 95 0.012
oocyte construction GO:0007308 2 0.012
sensory perception GO:0007600 245 0.012
regulation of actin filament length GO:0030832 45 0.012
striated muscle myosin thick filament assembly GO:0071688 1 0.011
protein maturation GO:0051604 176 0.011
regulation of rho gtpase activity GO:0032319 58 0.011
mitotic cell cycle GO:0000278 195 0.011
adult behavior GO:0030534 135 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
cell growth GO:0016049 130 0.011
negative regulation of protein metabolic process GO:0051248 282 0.011
endomembrane system organization GO:0010256 147 0.011
lung development GO:0030324 164 0.011
rna interference GO:0016246 2 0.011
muscle system process GO:0003012 141 0.011
defecation GO:0030421 1 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
positive regulation of organelle organization GO:0010638 128 0.011
protein localization to membrane GO:0072657 108 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
regulation of myotube differentiation GO:0010830 62 0.011
muscular septum morphogenesis GO:0003150 4 0.011
mesoderm formation GO:0001707 62 0.011
regulation of kinase activity GO:0043549 249 0.011
central nervous system neuron development GO:0021954 67 0.011
regulation of protein transport GO:0051223 163 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
anatomical structure homeostasis GO:0060249 145 0.011
muscle contraction GO:0006936 101 0.011
regulation of cell cycle process GO:0010564 160 0.011
hormone secretion GO:0046879 128 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
regulation of multi organism process GO:0043900 111 0.011
limb morphogenesis GO:0035108 149 0.011
regulation of protein kinase activity GO:0045859 232 0.011
cytokine production GO:0001816 319 0.011
regulation of cell adhesion GO:0030155 154 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
oocyte axis specification GO:0007309 2 0.011
organelle localization GO:0051640 179 0.011
response to extracellular stimulus GO:0009991 127 0.011
response to acid chemical GO:0001101 111 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.011
phospholipid metabolic process GO:0006644 87 0.011
rac protein signal transduction GO:0016601 13 0.011
cellular response to lipid GO:0071396 145 0.010
skin development GO:0043588 220 0.010
nuclear transport GO:0051169 139 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
cellular protein catabolic process GO:0044257 155 0.010
mitotic cytokinesis GO:0000281 4 0.010
limb development GO:0060173 166 0.010
fertilization GO:0009566 127 0.010
regulation of jnk cascade GO:0046328 62 0.010
metanephros development GO:0001656 79 0.010
ensheathment of neurons GO:0007272 76 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
digestive tract morphogenesis GO:0048546 147 0.010
neuron projection extension GO:1990138 64 0.010
mapk cascade GO:0000165 281 0.010
digestive system development GO:0055123 200 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
regulation of homeostatic process GO:0032844 182 0.010
muscle cell development GO:0055001 133 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
positive regulation of neuron projection development GO:0010976 79 0.010
response to inorganic substance GO:0010035 96 0.010
body morphogenesis GO:0010171 45 0.010
i kappab kinase nf kappab signaling GO:0007249 85 0.010
endocytosis GO:0006897 168 0.010
mesodermal cell migration GO:0008078 4 0.010
cell activation involved in immune response GO:0002263 126 0.010
regulation of transferase activity GO:0051338 263 0.010
neuron neuron synaptic transmission GO:0007270 69 0.010
nucleotide biosynthetic process GO:0009165 78 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
mitotic cell cycle process GO:1903047 159 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
regulation of transmembrane transport GO:0034762 128 0.010
nuclear division GO:0000280 158 0.010

Evc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
disease of cellular proliferation DOID:14566 0 0.016
musculoskeletal system disease DOID:17 0 0.014
sensory system disease DOID:0050155 0 0.012
cancer DOID:162 0 0.012
bone disease DOID:0080001 0 0.011
connective tissue disease DOID:65 0 0.011
organ system cancer DOID:0050686 0 0.011