Mus musculus

13 known processes

Exosc10

exosome component 10

(Aliases: p2,p3,p4,RRP6,PM/Scl-100,PM-Scl,Pmscl2)

Exosc10 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna processing GO:0006396 105 0.421
Human
mrna metabolic process GO:0016071 84 0.318
Human
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.286
ribonucleoprotein complex subunit organization GO:0071826 28 0.228
rna splicing GO:0008380 54 0.217
nuclear transport GO:0051169 139 0.203
mrna processing GO:0006397 63 0.154
mrna splicing via spliceosome GO:0000398 43 0.151
regulation of cell cycle process GO:0010564 160 0.150
rna splicing via transesterification reactions GO:0000375 43 0.131
nucleocytoplasmic transport GO:0006913 139 0.120
meiotic cell cycle GO:0051321 122 0.113
apoptotic signaling pathway GO:0097190 306 0.108
peptidyl amino acid modification GO:0018193 336 0.107
intracellular protein transport GO:0006886 204 0.106
covalent chromatin modification GO:0016569 163 0.104
internal protein amino acid acetylation GO:0006475 42 0.097
nuclear division GO:0000280 158 0.096
skeletal system development GO:0001501 356 0.090
maturation of 5 8s rrna GO:0000460 1 0.084
Human
purine ribonucleotide metabolic process GO:0009150 290 0.083
organelle fission GO:0048285 170 0.077
chromatin organization GO:0006325 206 0.073
organonitrogen compound catabolic process GO:1901565 264 0.069
endonucleolytic cleavage of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000479 1 0.068
dna metabolic process GO:0006259 303 0.065
meiotic nuclear division GO:0007126 115 0.063
stem cell development GO:0048864 219 0.058
mitotic cell cycle GO:0000278 195 0.055
blastocyst development GO:0001824 80 0.054
organelle assembly GO:0070925 177 0.053
regulation of organelle organization GO:0033043 289 0.053
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 1 0.052
ribonucleotide metabolic process GO:0009259 291 0.052
microtubule based process GO:0007017 236 0.052
stem cell maintenance GO:0019827 130 0.051
single organism nuclear import GO:1902593 95 0.048
regulation of mrna processing GO:0050684 41 0.047
peptidyl lysine modification GO:0018205 77 0.047
development of primary sexual characteristics GO:0045137 143 0.046
protein localization to organelle GO:0033365 185 0.046
regulation of cell cycle GO:0051726 281 0.046
mitotic cell cycle process GO:1903047 159 0.045
positive regulation of cellular amine metabolic process GO:0033240 5 0.043
pole plasm assembly GO:0007315 2 0.041
immune effector process GO:0002252 321 0.041
establishment of protein localization to organelle GO:0072594 118 0.041
regulation of mrna metabolic process GO:1903311 43 0.040
cellular hyperosmotic salinity response GO:0071475 0 0.040
ribonucleoside catabolic process GO:0042454 206 0.039
cellular ketone metabolic process GO:0042180 84 0.038
cellular nitrogen compound catabolic process GO:0044270 280 0.038
Human
regulation of cellular ketone metabolic process GO:0010565 66 0.038
germ cell development GO:0007281 185 0.038
heterocycle catabolic process GO:0046700 280 0.037
Human
endocytosis GO:0006897 168 0.037
regulation of cytoplasmic transport GO:1903649 112 0.036
cellular amino acid metabolic process GO:0006520 103 0.035
peptidyl lysine acetylation GO:0018394 45 0.035
gene silencing by mirna GO:0035195 10 0.035
amine metabolic process GO:0009308 45 0.035
ribose phosphate metabolic process GO:0019693 291 0.034
purine nucleoside triphosphate catabolic process GO:0009146 203 0.034
defense response to other organism GO:0098542 197 0.034
ribonucleoside triphosphate metabolic process GO:0009199 220 0.033
stem cell differentiation GO:0048863 268 0.033
histone h4 k16 acetylation GO:0043984 3 0.032
gonad development GO:0008406 141 0.032
synapsis GO:0007129 34 0.031
maturation of lsu rrna GO:0000470 1 0.031
purine nucleoside metabolic process GO:0042278 241 0.031
regulation of intracellular transport GO:0032386 159 0.031
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.031
Human
cellular amine metabolic process GO:0044106 44 0.031
spermatogenesis GO:0007283 284 0.031
alternative mrna splicing via spliceosome GO:0000380 12 0.030
nucleoside phosphate metabolic process GO:0006753 338 0.030
purine containing compound metabolic process GO:0072521 311 0.030
regulation of alternative mrna splicing via spliceosome GO:0000381 8 0.030
cellular response to dna damage stimulus GO:0006974 207 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
regulation of protein localization GO:0032880 231 0.028
nucleotide catabolic process GO:0009166 217 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
cytoplasmic transport GO:0016482 234 0.028
protein localization to nucleus GO:0034504 121 0.027
regulation of cellular amino acid metabolic process GO:0006521 5 0.027
response to organonitrogen compound GO:0010243 246 0.027
organophosphate catabolic process GO:0046434 232 0.027
regulation of establishment of protein localization GO:0070201 181 0.027
leukocyte differentiation GO:0002521 342 0.027
nucleoside triphosphate catabolic process GO:0009143 205 0.027
purine containing compound catabolic process GO:0072523 213 0.027
ribonucleoside triphosphate catabolic process GO:0009203 199 0.026
protein acylation GO:0043543 64 0.026
protein import into nucleus GO:0006606 95 0.026
purine ribonucleotide catabolic process GO:0009154 208 0.026
cellular response to organic cyclic compound GO:0071407 87 0.026
lymphocyte differentiation GO:0030098 242 0.026
meiotic cell cycle process GO:1903046 77 0.026
regulation of protein targeting GO:1903533 61 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
ribonucleotide catabolic process GO:0009261 208 0.025
ncrna processing GO:0034470 26 0.025
Human
purine nucleoside triphosphate metabolic process GO:0009144 226 0.025
dendrite development GO:0016358 115 0.024
nitrogen compound transport GO:0071705 271 0.024
receptor mediated endocytosis GO:0006898 51 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.024
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.024
male gamete generation GO:0048232 285 0.024
positive regulation of intracellular protein transport GO:0090316 42 0.023
regulation of rna splicing GO:0043484 37 0.023
protein targeting GO:0006605 143 0.023
organic cyclic compound catabolic process GO:1901361 295 0.023
Human
nucleolus organization GO:0007000 5 0.023
regulation of protein import into nucleus GO:0042306 52 0.023
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.022
oocyte anterior posterior axis specification GO:0007314 2 0.022
defense response to bacterium GO:0042742 119 0.022
regulation of cell division GO:0051302 76 0.022
nucleoside metabolic process GO:0009116 246 0.022
nuclear import GO:0051170 95 0.022
response to organic cyclic compound GO:0014070 198 0.022
maintenance of location GO:0051235 89 0.022
synapse organization GO:0050808 125 0.021
cell division GO:0051301 120 0.021
spermatid differentiation GO:0048515 115 0.021
multicellular organism growth GO:0035264 161 0.021
regulation of cellular component biogenesis GO:0044087 181 0.021
molting cycle GO:0042303 90 0.020
gland development GO:0048732 330 0.020
cellular response to oxidative stress GO:0034599 76 0.020
histone acetylation GO:0016573 41 0.020
regulation of cellular amine metabolic process GO:0033238 20 0.020
ribonucleoside monophosphate catabolic process GO:0009158 57 0.020
regulation of nucleocytoplasmic transport GO:0046822 73 0.020
ribonucleoside monophosphate metabolic process GO:0009161 80 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.019
regulation of mrna splicing via spliceosome GO:0048024 32 0.019
response to radiation GO:0009314 165 0.019
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 1 0.019
neuron death GO:0070997 154 0.018
embryonic skeletal system development GO:0048706 120 0.018
protein import GO:0017038 101 0.018
regulation of nuclear division GO:0051783 56 0.018
protein ubiquitination GO:0016567 171 0.018
nucleotide metabolic process GO:0009117 332 0.018
positive regulation of dna templated transcription elongation GO:0032786 2 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
rna 5 end processing GO:0000966 1 0.018
histone h4 acetylation GO:0043967 10 0.017
response to lipopolysaccharide GO:0032496 128 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
chromatin modification GO:0016568 187 0.017
regulation of mitotic cell cycle phase transition GO:1901990 73 0.017
response to oxidative stress GO:0006979 123 0.017
oocyte construction GO:0007308 2 0.017
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 2 0.017
chromosome organization involved in meiosis GO:0070192 39 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
cleavage involved in rrna processing GO:0000469 1 0.017
digestive system development GO:0055123 200 0.017
aromatic compound catabolic process GO:0019439 286 0.017
Human
single fertilization GO:0007338 82 0.016
nucleoside catabolic process GO:0009164 206 0.016
positive regulation of gluconeogenesis by positive regulation of transcription from rna polymerase ii promoter GO:0035948 5 0.016
gtp catabolic process GO:0006184 143 0.016
cytokine production GO:0001816 319 0.016
nucleoside monophosphate catabolic process GO:0009125 59 0.016
endonucleolytic cleavage involved in rrna processing GO:0000478 1 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
mrna transport GO:0051028 13 0.016
positive regulation of cell development GO:0010720 237 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
positive regulation of intracellular transport GO:0032388 70 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.015
skeletal system morphogenesis GO:0048705 203 0.015
establishment of rna localization GO:0051236 18 0.015
negative regulation of immune system process GO:0002683 209 0.015
nucleic acid transport GO:0050657 18 0.015
mitotic nuclear division GO:0007067 48 0.015
macromolecule methylation GO:0043414 120 0.015
dna templated transcription initiation GO:0006352 13 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.014
methylation GO:0032259 134 0.014
response to inorganic substance GO:0010035 96 0.014
regulation of neuron death GO:1901214 134 0.014
defense response to virus GO:0051607 68 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
response to acid chemical GO:0001101 111 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
embryonic skeletal system morphogenesis GO:0048704 91 0.014
response to reactive oxygen species GO:0000302 56 0.014
nucleobase containing compound transport GO:0015931 27 0.013
myeloid cell differentiation GO:0030099 233 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
response to light stimulus GO:0009416 135 0.013
rna transport GO:0050658 18 0.013
protein alkylation GO:0008213 81 0.013
regulation of protein transport GO:0051223 163 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
internal peptidyl lysine acetylation GO:0018393 42 0.013
positive regulation of protein localization to nucleus GO:1900182 30 0.013
protein maturation GO:0051604 176 0.013
blastocyst growth GO:0001832 23 0.013
spermatid development GO:0007286 108 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
atp metabolic process GO:0046034 75 0.012
cellularization GO:0007349 1 0.012
chromatin remodeling GO:0006338 32 0.012
regulation of cellular response to stress GO:0080135 159 0.012
transcription coupled nucleotide excision repair GO:0006283 2 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
actin cytoskeleton organization GO:0030036 220 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
metencephalon development GO:0022037 89 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
transmembrane transport GO:0055085 412 0.012
positive regulation of cell cycle GO:0045787 92 0.012
fertilization GO:0009566 127 0.012
regulation of protein complex assembly GO:0043254 83 0.012
anatomical structure homeostasis GO:0060249 145 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
rna dependent dna replication GO:0006278 3 0.012
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter GO:0072364 7 0.012
positive regulation of immune effector process GO:0002699 107 0.012
cellular response to lipid GO:0071396 145 0.012
positive regulation of growth GO:0045927 104 0.012
regulation of meiotic cell cycle GO:0051445 34 0.011
regulation of antimicrobial humoral response GO:0002759 3 0.011
sensory perception GO:0007600 245 0.011
t cell activation GO:0042110 289 0.011
negative regulation of cell cycle process GO:0010948 69 0.011
histone modification GO:0016570 159 0.011
t cell differentiation GO:0030217 174 0.011
regulation of multi organism process GO:0043900 111 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
skin development GO:0043588 220 0.011
response to oxygen levels GO:0070482 62 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
negative regulation of cell cycle GO:0045786 123 0.011
regulation of cell migration GO:0030334 219 0.011
microtubule nucleation GO:0007020 2 0.011
snorna metabolic process GO:0016074 1 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
positive regulation of cell death GO:0010942 224 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
negative regulation of neuron death GO:1901215 98 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
carbohydrate metabolic process GO:0005975 230 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
regulation of microtubule based process GO:0032886 52 0.010
macromolecular complex disassembly GO:0032984 43 0.010
cellular response to starvation GO:0009267 57 0.010
cell activation involved in immune response GO:0002263 126 0.010
protein processing GO:0016485 163 0.010
positive regulation of protein import into nucleus GO:0042307 26 0.010
transmission of nerve impulse GO:0019226 76 0.010

Exosc10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.076
disease of anatomical entity DOID:7 0 0.076
nervous system disease DOID:863 0 0.076
retinal disease DOID:5679 0 0.069
eye and adnexa disease DOID:1492 0 0.069
eye disease DOID:5614 0 0.069
retinal degeneration DOID:8466 0 0.059
retinitis pigmentosa DOID:10584 0 0.030