Mus musculus

228 known processes

Ezh2

enhancer of zeste homolog 2 (Drosophila)

(Aliases: Enx-1,KMT6,mKIAA4065,KIAA4065,Enx1h,MGC90723)

Ezh2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone lysine methylation GO:0034968 50 1.000
histone h3 k9 methylation GO:0051567 17 1.000
Fly
histone methylation GO:0016571 71 1.000
protein methylation GO:0006479 81 1.000
dna metabolic process GO:0006259 303 1.000
positive regulation of histone h3 k27 methylation GO:0061087 4 1.000
chromatin organization GO:0006325 206 1.000
covalent chromatin modification GO:0016569 163 1.000
positive regulation of histone h3 k9 methylation GO:0051574 4 1.000
regulation of histone h3 k9 methylation GO:0051570 8 0.999
negative regulation of histone methylation GO:0031061 10 0.999
regulation of histone methylation GO:0031060 30 0.999
dna modification GO:0006304 50 0.999
positive regulation of chromatin modification GO:1903310 28 0.998
methylation GO:0032259 134 0.998
histone modification GO:0016570 159 0.997
dna hypermethylation GO:0044026 3 0.997
positive regulation of histone methylation GO:0031062 16 0.997
mitotic cell cycle process GO:1903047 159 0.996
dna conformation change GO:0071103 37 0.994
dna alkylation GO:0006305 43 0.994
chromatin assembly GO:0031497 13 0.994
protein alkylation GO:0008213 81 0.988
positive regulation of histone modification GO:0031058 28 0.980
chromatin silencing GO:0006342 15 0.979
negative regulation of chromosome organization GO:2001251 30 0.979
regulation of chromatin modification GO:1903308 57 0.976
positive regulation of histone h3 k4 methylation GO:0051571 5 0.971
chromatin modification GO:0016568 187 0.970
histone acetylation GO:0016573 41 0.954
peptidyl amino acid modification GO:0018193 336 0.952
Mouse Fly
peptidyl lysine modification GO:0018205 77 0.950
Mouse Fly
gene silencing by rna GO:0031047 19 0.945
meiotic cell cycle GO:0051321 122 0.937
gene silencing GO:0016458 38 0.935
dna replication GO:0006260 52 0.933
recombinational repair GO:0000725 21 0.923
regulation of histone h3 k27 methylation GO:0061085 6 0.921
response to ionizing radiation GO:0010212 42 0.913
negative regulation of gene expression epigenetic GO:0045814 15 0.896
Human
microtubule cytoskeleton organization GO:0000226 157 0.891
genitalia development GO:0048806 37 0.882
dendrite development GO:0016358 115 0.880
Fly
negative regulation of cellular component organization GO:0051129 194 0.877
negative regulation of histone h3 k9 methylation GO:0051573 4 0.867
development of primary sexual characteristics GO:0045137 143 0.867
macromolecule methylation GO:0043414 120 0.861
rna interference GO:0016246 2 0.850
mitotic cytokinesis GO:0000281 4 0.841
spermatogenesis GO:0007283 284 0.835
protein dna complex subunit organization GO:0071824 28 0.817
regulation of chromosome organization GO:0033044 83 0.814
posttranscriptional gene silencing GO:0016441 10 0.811
dna methylation GO:0006306 43 0.800
histone h3 k27 methylation GO:0070734 11 0.799
digestive tract development GO:0048565 190 0.795
positive regulation of organelle organization GO:0010638 128 0.781
response to purine containing compound GO:0014074 28 0.770
microtubule based process GO:0007017 236 0.769
response to radiation GO:0009314 165 0.757
regulation of histone modification GO:0031056 56 0.746
peptidyl lysine acetylation GO:0018394 45 0.744
positive regulation of chromosome organization GO:2001252 33 0.728
digestive tract morphogenesis GO:0048546 147 0.702
regulation of dna methylation GO:0044030 12 0.690
response to molecule of bacterial origin GO:0002237 143 0.685
protein localization to chromatin GO:0071168 3 0.677
regulation of organelle organization GO:0033043 289 0.675
digestive system development GO:0055123 200 0.651
rhythmic process GO:0048511 174 0.647
chromatin assembly or disassembly GO:0006333 16 0.640
mitotic nuclear division GO:0007067 48 0.640
circadian rhythm GO:0007623 114 0.598
protein import GO:0017038 101 0.590
dna replication independent nucleosome assembly GO:0006336 1 0.585
gonad development GO:0008406 141 0.580
positive regulation of cellular amine metabolic process GO:0033240 5 0.571
nuclear transport GO:0051169 139 0.568
axon guidance GO:0007411 141 0.564
Fly
response to lipopolysaccharide GO:0032496 128 0.555
double strand break repair via homologous recombination GO:0000724 21 0.553
body morphogenesis GO:0010171 45 0.549
spindle assembly involved in mitosis GO:0090307 4 0.544
nuclear division GO:0000280 158 0.542
genetic imprinting GO:0071514 27 0.529
regulation of dna replication GO:0006275 17 0.528
germ cell development GO:0007281 185 0.521
Worm
protein localization to organelle GO:0033365 185 0.520
cellular amino acid metabolic process GO:0006520 103 0.517
mitotic sister chromatid segregation GO:0000070 14 0.515
tissue regeneration GO:0042246 22 0.515
organelle fission GO:0048285 170 0.510
dna repair GO:0006281 107 0.507
cellular response to dna damage stimulus GO:0006974 207 0.488
regulation of chromatin organization GO:1902275 57 0.488
positive regulation of protein modification process GO:0031401 299 0.479
Human
nucleosome positioning GO:0016584 4 0.477
response to organonitrogen compound GO:0010243 246 0.472
negative regulation of cellular protein metabolic process GO:0032269 247 0.470
dna packaging GO:0006323 30 0.468
response to amino acid GO:0043200 37 0.455
nucleocytoplasmic transport GO:0006913 139 0.450
posttranscriptional regulation of gene expression GO:0010608 155 0.449
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.444
establishment of protein localization to organelle GO:0072594 118 0.444
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.437
stem cell maintenance GO:0019827 130 0.418
negative regulation of cellular amine metabolic process GO:0033239 1 0.411
pore complex assembly GO:0046931 3 0.409
meiotic chromosome segregation GO:0045132 19 0.402
apoptotic signaling pathway GO:0097190 306 0.392
male gamete generation GO:0048232 285 0.392
chromosome segregation GO:0007059 48 0.385
dna templated transcription termination GO:0006353 4 0.382
wound healing GO:0042060 157 0.373
cellular response to organonitrogen compound GO:0071417 145 0.372
negative regulation of ras protein signal transduction GO:0046580 18 0.358
response to organic cyclic compound GO:0014070 198 0.351
organelle assembly GO:0070925 177 0.349
gliogenesis GO:0042063 141 0.334
intrinsic apoptotic signaling pathway GO:0097193 132 0.334
endocytosis GO:0006897 168 0.329
regulation of apoptotic signaling pathway GO:2001233 197 0.326
posttranscriptional gene silencing by rna GO:0035194 10 0.323
interspecies interaction between organisms GO:0044419 83 0.322
response to alcohol GO:0097305 48 0.318
spermatid development GO:0007286 108 0.317
dna recombination GO:0006310 92 0.314
regulation of transferase activity GO:0051338 263 0.305
Human
double strand break repair GO:0006302 48 0.297
response to alkaloid GO:0043279 34 0.292
negative regulation of viral process GO:0048525 23 0.291
negative regulation of cell cycle phase transition GO:1901988 48 0.291
intracellular protein transport GO:0006886 204 0.289
nuclear dna replication GO:0033260 3 0.286
maintenance of dna methylation GO:0010216 4 0.273
protein localization to nucleus GO:0034504 121 0.270
ribonucleoside triphosphate metabolic process GO:0009199 220 0.270
Human
cellular response to amino acid stimulus GO:0071230 29 0.266
rna localization GO:0006403 23 0.264
muscle system process GO:0003012 141 0.264
cellular ketone metabolic process GO:0042180 84 0.261
hepaticobiliary system development GO:0061008 67 0.261
cell cycle checkpoint GO:0000075 47 0.259
dna dependent dna replication GO:0006261 24 0.257
regulation of cellular ketone metabolic process GO:0010565 66 0.256
internal protein amino acid acetylation GO:0006475 42 0.255
regulation of histone h3 k4 methylation GO:0051569 12 0.249
regeneration GO:0031099 38 0.248
spermatid differentiation GO:0048515 115 0.243
determination of adult lifespan GO:0008340 11 0.235
Worm
small gtpase mediated signal transduction GO:0007264 97 0.232
negative regulation of protein modification process GO:0031400 163 0.231
cellular amine metabolic process GO:0044106 44 0.222
chromosome organization involved in meiosis GO:0070192 39 0.222
embryonic digestive tract development GO:0048566 27 0.221
negative regulation of cell proliferation GO:0008285 296 0.220
female gamete generation GO:0007292 74 0.220
cytokinesis GO:0000910 17 0.218
actin cytoskeleton organization GO:0030036 220 0.216
cell fate commitment GO:0045165 210 0.207
regulation of cytoskeleton organization GO:0051493 122 0.206
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.203
s adenosylhomocysteine metabolic process GO:0046498 1 0.201
camera type eye development GO:0043010 266 0.198
regulation of cellular amino acid metabolic process GO:0006521 5 0.196
negative regulation of protein metabolic process GO:0051248 282 0.194
regulation of cellular component biogenesis GO:0044087 181 0.194
membrane organization GO:0061024 245 0.193
nucleoside triphosphate metabolic process GO:0009141 230 0.191
Human
negative regulation of chromatin modification GO:1903309 19 0.191
response to caffeine GO:0031000 6 0.188
internal peptidyl lysine acetylation GO:0018393 42 0.187
regulation of protein kinase activity GO:0045859 232 0.181
Human
sister chromatid segregation GO:0000819 20 0.180
regulation of cell cycle g2 m phase transition GO:1902749 10 0.173
negative regulation of chromatin silencing GO:0031936 1 0.170
embryonic digestive tract morphogenesis GO:0048557 17 0.168
rna dependent dna replication GO:0006278 3 0.168
double strand break repair via nonhomologous end joining GO:0006303 10 0.168
non recombinational repair GO:0000726 10 0.166
cellular response to oxidative stress GO:0034599 76 0.165
cytoplasmic transport GO:0016482 234 0.165
regulation of multi organism process GO:0043900 111 0.158
regulation of cell cycle GO:0051726 281 0.154
response to oxidative stress GO:0006979 123 0.152
mitotic cell cycle GO:0000278 195 0.145
response to steroid hormone GO:0048545 56 0.145
exocrine pancreas development GO:0031017 7 0.143
base excision repair GO:0006284 9 0.143
cell fate specification GO:0001708 72 0.141
response to inorganic substance GO:0010035 96 0.141
ras protein signal transduction GO:0007265 77 0.140
regulation of actin filament based process GO:0032970 99 0.139
mitotic g2 dna damage checkpoint GO:0007095 8 0.137
receptor mediated endocytosis GO:0006898 51 0.135
cellular response to growth factor stimulus GO:0071363 197 0.135
regulation of cell cycle phase transition GO:1901987 77 0.132
regulation of cellular amine metabolic process GO:0033238 20 0.131
single organism nuclear import GO:1902593 95 0.131
meiotic cell cycle process GO:1903046 77 0.130
liver development GO:0001889 66 0.129
protein targeting GO:0006605 143 0.128
negative regulation of cell growth GO:0030308 44 0.127
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.122
multicellular organismal aging GO:0010259 24 0.122
Worm
nucleobase containing compound transport GO:0015931 27 0.120
histone h3 deacetylation GO:0070932 8 0.119
protein modification by small protein conjugation or removal GO:0070647 207 0.119
response to extracellular stimulus GO:0009991 127 0.118
stem cell differentiation GO:0048863 268 0.117
Human
mitotic spindle organization GO:0007052 10 0.117
response to drug GO:0042493 75 0.116
protein import into nucleus GO:0006606 95 0.115
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.113
developmental growth involved in morphogenesis GO:0060560 138 0.113
meiotic nuclear division GO:0007126 115 0.107
neuron apoptotic process GO:0051402 142 0.106
response to estrogen GO:0043627 24 0.105
mrna transport GO:0051028 13 0.105
muscle cell differentiation GO:0042692 261 0.105
regulation of mrna splicing via spliceosome GO:0048024 32 0.104
nitrogen compound transport GO:0071705 271 0.103
dna ligation GO:0006266 3 0.103
innate immune response GO:0045087 157 0.102
segmentation GO:0035282 93 0.101
chromosome condensation GO:0030261 10 0.101
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.100
heterochromatin organization GO:0070828 4 0.099
regulation of striated muscle contraction GO:0006942 25 0.098
atp metabolic process GO:0046034 75 0.098
regulation of protein stability GO:0031647 52 0.097
regulation of gene expression by genetic imprinting GO:0006349 15 0.095
regulation of cellular response to stress GO:0080135 159 0.094
negative regulation of cell cycle process GO:0010948 69 0.093
engulfment of apoptotic cell GO:0043652 3 0.093
nucleic acid transport GO:0050657 18 0.093
regulation of mitotic cell cycle GO:0007346 126 0.092
embryonic organ morphogenesis GO:0048562 276 0.092
histone h3 k9 dimethylation GO:0036123 4 0.091
response to decreased oxygen levels GO:0036293 59 0.090
negative regulation of growth GO:0045926 99 0.086
neuron migration GO:0001764 122 0.085
intrahepatic bile duct development GO:0035622 2 0.085
alpha amino acid metabolic process GO:1901605 59 0.085
lipid biosynthetic process GO:0008610 179 0.085
protein complex disassembly GO:0043241 40 0.084
purine nucleoside triphosphate metabolic process GO:0009144 226 0.084
Human
actomyosin structure organization GO:0031032 56 0.084
regulation of cytoplasmic transport GO:1903649 112 0.084
dna methylation on cytosine GO:0032776 5 0.083
cellular response to organic cyclic compound GO:0071407 87 0.081
response to metal ion GO:0010038 47 0.081
cell cell recognition GO:0009988 44 0.081
dna methylation involved in gamete generation GO:0043046 15 0.080
meiosis i GO:0007127 60 0.079
negative regulation of cell cycle GO:0045786 123 0.079
centromere complex assembly GO:0034508 3 0.079
histone h4 deacetylation GO:0070933 4 0.078
nucleosome assembly GO:0006334 7 0.077
peptidyl lysine methylation GO:0018022 29 0.076
Mouse Fly
nls bearing protein import into nucleus GO:0006607 2 0.076
mrna 3 end processing GO:0031124 16 0.076
chromatin remodeling GO:0006338 32 0.075
atp dependent chromatin remodeling GO:0043044 9 0.075
cell growth GO:0016049 130 0.075
regulation of cell cycle g1 s phase transition GO:1902806 35 0.073
production of molecular mediator of immune response GO:0002440 103 0.073
regulation of nuclear division GO:0051783 56 0.073
aromatic compound catabolic process GO:0019439 286 0.073
Human
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.072
positive regulation of intracellular transport GO:0032388 70 0.072
regulation of rna splicing GO:0043484 37 0.071
sensory organ morphogenesis GO:0090596 242 0.070
nucleoside triphosphate catabolic process GO:0009143 205 0.069
Human
locomotory behavior GO:0007626 195 0.069
negative regulation of organelle organization GO:0010639 90 0.068
amine metabolic process GO:0009308 45 0.068
cell type specific apoptotic process GO:0097285 268 0.068
citrate metabolic process GO:0006101 3 0.067
postreplication repair GO:0006301 5 0.064
anatomical structure homeostasis GO:0060249 145 0.064
regulation of cell migration GO:0030334 219 0.064
positive regulation of programmed cell death GO:0043068 218 0.064
notch signaling pathway GO:0007219 71 0.063
generation of precursor metabolites and energy GO:0006091 103 0.063
nuclear import GO:0051170 95 0.062
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.062
retina development in camera type eye GO:0060041 119 0.061
ribonucleoside catabolic process GO:0042454 206 0.061
Human
organelle localization GO:0051640 179 0.061
attachment of spindle microtubules to kinetochore GO:0008608 4 0.060
purine nucleoside catabolic process GO:0006152 205 0.059
Human
negative regulation of multi organism process GO:0043901 68 0.059
organic cyclic compound catabolic process GO:1901361 295 0.059
Human
positive regulation of nfat protein import into nucleus GO:0051533 1 0.058
purine ribonucleoside metabolic process GO:0046128 241 0.058
Human
cellular response to cytokine stimulus GO:0071345 189 0.058
ribose phosphate metabolic process GO:0019693 291 0.058
Human
mitotic chromosome condensation GO:0007076 1 0.058
regulation of organelle assembly GO:1902115 19 0.057
male meiosis GO:0007140 37 0.057
cofactor metabolic process GO:0051186 80 0.056
cell recognition GO:0008037 83 0.056
stem cell development GO:0048864 219 0.055
Human
termination of rna polymerase ii transcription GO:0006369 1 0.055
retina morphogenesis in camera type eye GO:0060042 45 0.055
regulation of hormone levels GO:0010817 211 0.055
blastocyst development GO:0001824 80 0.054
negative regulation of viral transcription GO:0032897 3 0.054
purine nucleoside monophosphate catabolic process GO:0009128 58 0.054
small molecule biosynthetic process GO:0044283 132 0.054
regulation of androgen receptor signaling pathway GO:0060765 3 0.054
cellular response to metal ion GO:0071248 31 0.054
mrna metabolic process GO:0016071 84 0.054
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.053
Human
regulation of establishment of protein localization GO:0070201 181 0.053
nuclear export GO:0051168 34 0.053
response to gamma radiation GO:0010332 22 0.053
negative regulation of mitotic sister chromatid segregation GO:0033048 7 0.053
gland development GO:0048732 330 0.052
axonogenesis GO:0007409 274 0.052
Fly
s adenosylmethionine metabolic process GO:0046500 2 0.052
multicellular organism growth GO:0035264 161 0.052
response to temperature stimulus GO:0009266 55 0.051
coenzyme metabolic process GO:0006732 52 0.050
response to oxygen levels GO:0070482 62 0.050
protein acylation GO:0043543 64 0.050
meiotic chromosome condensation GO:0010032 3 0.050
regulation of protein serine threonine kinase activity GO:0071900 157 0.050
Human
adult behavior GO:0030534 135 0.050
homeostasis of number of cells GO:0048872 210 0.049
epidermis development GO:0008544 187 0.049
regulation of system process GO:0044057 200 0.049
gastrulation GO:0007369 116 0.048
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.048
phagocytosis GO:0006909 66 0.047
negative regulation of apoptotic signaling pathway GO:2001234 104 0.047
positive regulation of apoptotic process GO:0043065 217 0.046
dna catabolic process GO:0006308 19 0.046
response to heat GO:0009408 27 0.046
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.045
regulation of lymphocyte activation GO:0051249 240 0.045
regulation of protein complex disassembly GO:0043244 28 0.045
dna geometric change GO:0032392 7 0.045
b cell activation GO:0042113 161 0.045
regulation of neuron differentiation GO:0045664 281 0.045
regulation of centriole replication GO:0046599 1 0.045
regulation of neuron apoptotic process GO:0043523 122 0.044
response to testosterone GO:0033574 3 0.044
positive regulation of transferase activity GO:0051347 167 0.044
Human
purine nucleoside triphosphate catabolic process GO:0009146 203 0.044
Human
regulation of cell activation GO:0050865 289 0.044
cell division GO:0051301 120 0.044
Worm
histone h4 k20 methylation GO:0034770 8 0.044
regulation of protein localization GO:0032880 231 0.043
cellular protein complex disassembly GO:0043624 36 0.043
microtubule organizing center organization GO:0031023 28 0.042
regulation of muscle system process GO:0090257 80 0.042
defense response to other organism GO:0098542 197 0.042
inflammatory response GO:0006954 244 0.042
negative regulation of dna replication GO:0008156 4 0.042
positive regulation of histone acetylation GO:0035066 8 0.042
dna duplex unwinding GO:0032508 7 0.042
maintenance of protein location in nucleus GO:0051457 2 0.042
peptidyl serine phosphorylation GO:0018105 74 0.042
cellular chemical homeostasis GO:0055082 215 0.042
chromatin silencing at rdna GO:0000183 3 0.042
cardiac muscle cell development GO:0055013 39 0.042
metencephalon development GO:0022037 89 0.041
regulation of mrna stability GO:0043488 23 0.041
response to nutrient levels GO:0031667 109 0.041
regulation of double strand break repair via nonhomologous end joining GO:2001032 2 0.040
establishment of organelle localization GO:0051656 122 0.040
regulation of cell projection organization GO:0031344 206 0.040
response to light stimulus GO:0009416 135 0.040
pancreas development GO:0031016 57 0.040
response to growth factor GO:0070848 198 0.040
heterocycle catabolic process GO:0046700 280 0.039
Human
regulation of cell division GO:0051302 76 0.039
3 utr mediated mrna stabilization GO:0070935 2 0.038
cellular response to inorganic substance GO:0071241 37 0.038
response to hydrogen peroxide GO:0042542 32 0.038
regulation of nucleocytoplasmic transport GO:0046822 73 0.038
ossification GO:0001503 216 0.037
fungiform papilla development GO:0061196 6 0.037
regulation of circadian rhythm GO:0042752 58 0.037
cellular response to lipid GO:0071396 145 0.037
fungiform papilla morphogenesis GO:0061197 5 0.037
positive regulation of nervous system development GO:0051962 221 0.036
nucleotide metabolic process GO:0009117 332 0.036
Human
positive regulation of meiotic cell cycle GO:0051446 15 0.036
regulation of protein import into nucleus GO:0042306 52 0.036
positive regulation of protein transport GO:0051222 93 0.035
histone mrna metabolic process GO:0008334 3 0.035
regulation of sarcomere organization GO:0060297 4 0.035
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.035
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.035
chorion development GO:0060717 7 0.035
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.035
segment specification GO:0007379 15 0.035
calcium mediated signaling GO:0019722 46 0.035
viral life cycle GO:0019058 36 0.035
regulation of protein targeting GO:1903533 61 0.035
cellular response to nerve growth factor stimulus GO:1990090 3 0.034
hormone secretion GO:0046879 128 0.034
exocrine system development GO:0035272 45 0.034
cardiac cell development GO:0055006 41 0.034
oxidation reduction process GO:0055114 342 0.034
maintenance of location GO:0051235 89 0.033
cellular response to hormone stimulus GO:0032870 150 0.033
regulation of defense response GO:0031347 233 0.032
regulation of intracellular protein transport GO:0033157 82 0.032
neuron death GO:0070997 154 0.032
positive regulation of cell activation GO:0050867 158 0.032
fatty acid biosynthetic process GO:0006633 41 0.031
peptide transport GO:0015833 133 0.031
regulation of chromatin silencing GO:0031935 2 0.031
regulation of histone acetylation GO:0035065 19 0.031
monocarboxylic acid metabolic process GO:0032787 191 0.031
telomere maintenance GO:0000723 19 0.031
extrinsic apoptotic signaling pathway GO:0097191 126 0.031
reciprocal dna recombination GO:0035825 16 0.030
regulation of attachment of spindle microtubules to kinetochore GO:0051988 3 0.030
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.030
regulation of intracellular transport GO:0032386 159 0.030
oogenesis GO:0048477 56 0.030
centrosome organization GO:0051297 26 0.030
histone h3 k4 methylation GO:0051568 23 0.030
regulation of protein transport GO:0051223 163 0.029
negative regulation of intracellular signal transduction GO:1902532 167 0.029
regulation of muscle contraction GO:0006937 49 0.029
cell junction organization GO:0034330 77 0.029
protein depolymerization GO:0051261 34 0.029
dna integrity checkpoint GO:0031570 28 0.029
cellular response to acid chemical GO:0071229 68 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.028
Human
response to acid chemical GO:0001101 111 0.028
pharynx development GO:0060465 1 0.028
regulation of actin cytoskeleton organization GO:0032956 84 0.028
atp catabolic process GO:0006200 55 0.028
regulation of receptor biosynthetic process GO:0010869 2 0.028
actin filament organization GO:0007015 113 0.028
cell aging GO:0007569 35 0.028
cellular homeostasis GO:0019725 240 0.027
developmental cell growth GO:0048588 84 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
Human
nucleoside catabolic process GO:0009164 206 0.027
Human
single fertilization GO:0007338 82 0.027
dna unwinding involved in dna replication GO:0006268 5 0.027
regulation of secretion by cell GO:1903530 249 0.027
spindle organization GO:0007051 28 0.027
regulation of mrna processing GO:0050684 41 0.027
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
regulation of protein localization to nucleus GO:1900180 60 0.027
intracellular mrna localization GO:0008298 4 0.027
cellular lipid metabolic process GO:0044255 323 0.026
hematopoietic progenitor cell differentiation GO:0002244 143 0.026
regulation of neuron death GO:1901214 134 0.026
viral gene expression GO:0019080 3 0.026
regulation of cellular catabolic process GO:0031329 242 0.026
Human
cell cycle arrest GO:0007050 37 0.026
fertilization GO:0009566 127 0.026
cation transport GO:0006812 399 0.026
carboxylic acid biosynthetic process GO:0046394 86 0.025
regulation of kinase activity GO:0043549 249 0.025
Human
purine containing compound catabolic process GO:0072523 213 0.025
Human
negative regulation of cardiac muscle cell proliferation GO:0060044 5 0.025
establishment or maintenance of cell polarity GO:0007163 86 0.025
cellular response to abiotic stimulus GO:0071214 56 0.025
ameboidal type cell migration GO:0001667 128 0.025
g2 dna damage checkpoint GO:0031572 8 0.025
chromatin remodeling at centromere GO:0031055 2 0.025
histone ubiquitination GO:0016574 10 0.025
regulation of striated muscle cell differentiation GO:0051153 81 0.025
i kappab kinase nf kappab signaling GO:0007249 85 0.025
protein maturation GO:0051604 176 0.024
regulation of cell growth GO:0001558 91 0.024
skeletal system development GO:0001501 356 0.024
myeloid cell differentiation GO:0030099 233 0.024
rna 3 end processing GO:0031123 20 0.024
histone h2a monoubiquitination GO:0035518 1 0.024
nucleus organization GO:0006997 45 0.024
translation GO:0006412 93 0.023
placenta development GO:0001890 140 0.023
regulation of neuron projection development GO:0010975 169 0.023
response to reactive oxygen species GO:0000302 56 0.023
viral process GO:0016032 41 0.023
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.023

Ezh2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
peripheral neuropathy DOID:0060053 0 0.144
disease of anatomical entity DOID:7 0 0.144
nervous system disease DOID:863 0 0.144
neuropathy DOID:870 0 0.144
hereditary sensory neuropathy DOID:0050548 0 0.039
central nervous system disease DOID:331 0 0.025