Mus musculus

76 known processes

F2

coagulation factor II

(Aliases: thrombin,FII,Cf2,Cf-2)

F2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neutral lipid metabolic process GO:0006638 57 0.876
hemostasis GO:0007599 78 0.790
negative regulation of fibrinolysis GO:0051918 1 0.750
fibrinolysis GO:0042730 3 0.740
Human
acylglycerol metabolic process GO:0006639 55 0.713
regulation of response to wounding GO:1903034 189 0.700
Human Mouse
coagulation GO:0050817 78 0.698
sterol metabolic process GO:0016125 58 0.644
protein processing GO:0016485 163 0.579
Human
blood circulation GO:0008015 195 0.560
circulatory system process GO:0003013 197 0.559
protein lipid complex subunit organization GO:0071825 12 0.538
establishment of blood nerve barrier GO:0008065 3 0.504
wound healing GO:0042060 157 0.494
blood coagulation GO:0007596 76 0.493
cholesterol metabolic process GO:0008203 56 0.490
small molecule biosynthetic process GO:0044283 132 0.460
positive regulation of protein kinase c activity GO:1900020 1 0.440
steroid metabolic process GO:0008202 119 0.436
negative regulation of coagulation GO:0050819 11 0.423
Human Mouse
hexose metabolic process GO:0019318 98 0.420
regulation of cellular ketone metabolic process GO:0010565 66 0.418
carbohydrate metabolic process GO:0005975 230 0.418
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.416
plasma lipoprotein particle remodeling GO:0034369 6 0.412
organic acid biosynthetic process GO:0016053 86 0.411
negative regulation of hemostasis GO:1900047 11 0.403
Human Mouse
lipid biosynthetic process GO:0008610 179 0.400
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.384
regulation of hemostasis GO:1900046 28 0.371
Human Mouse
cellular lipid metabolic process GO:0044255 323 0.370
negative regulation of blood coagulation GO:0030195 11 0.370
Human Mouse
amine metabolic process GO:0009308 45 0.367
positive regulation of plasminogen activation GO:0010756 2 0.363
cellular carbohydrate metabolic process GO:0044262 119 0.361
extracellular structure organization GO:0043062 148 0.360
regulation of cellular amino acid metabolic process GO:0006521 5 0.341
triglyceride metabolic process GO:0006641 51 0.325
regulation of hormone levels GO:0010817 211 0.320
cofactor transport GO:0051181 4 0.313
negative regulation of proteolysis GO:0045861 74 0.304
Human
gland development GO:0048732 330 0.302
cellular ketone metabolic process GO:0042180 84 0.301
alcohol metabolic process GO:0006066 116 0.288
regulation of cellular amine metabolic process GO:0033238 20 0.287
positive regulation of cellular amine metabolic process GO:0033240 5 0.284
regulation of fibrinolysis GO:0051917 1 0.281
regulation of hydrolase activity GO:0051336 246 0.274
protein maturation GO:0051604 176 0.261
Human
cellular response to hormone stimulus GO:0032870 150 0.247
regulation of system process GO:0044057 200 0.247
negative regulation of hydrolase activity GO:0051346 71 0.247
regulation of secretion GO:0051046 274 0.244
lipid homeostasis GO:0055088 63 0.240
sensory organ morphogenesis GO:0090596 242 0.240
regulation of blood coagulation GO:0030193 28 0.236
Human Mouse
cellular amino acid metabolic process GO:0006520 103 0.235
extracellular matrix organization GO:0030198 147 0.232
regulation of proteolysis GO:0030162 164 0.232
Human
regulation of protein maturation GO:1903317 96 0.231
Human
skeletal system development GO:0001501 356 0.228
cellular amine metabolic process GO:0044106 44 0.221
glycerolipid metabolic process GO:0046486 122 0.219
glucose metabolic process GO:0006006 92 0.217
regulation of body fluid levels GO:0050878 162 0.213
regulation of wound healing GO:0061041 40 0.212
Human Mouse
oxidation reduction process GO:0055114 342 0.211
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.209
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.203
response to hypoxia GO:0001666 58 0.202
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.200
lipid localization GO:0010876 126 0.197
lipoprotein metabolic process GO:0042157 43 0.195
muscle cell differentiation GO:0042692 261 0.190
negative regulation of molecular function GO:0044092 258 0.189
inflammatory response GO:0006954 244 0.189
apoptotic signaling pathway GO:0097190 306 0.186
regulation of intestinal cholesterol absorption GO:0030300 4 0.184
extrinsic apoptotic signaling pathway GO:0097191 126 0.184
negative regulation of protein processing GO:0010955 79 0.183
Human
monocarboxylic acid metabolic process GO:0032787 191 0.183
regulation of inflammatory response GO:0050727 147 0.182
carboxylic acid biosynthetic process GO:0046394 86 0.182
sphingolipid metabolic process GO:0006665 45 0.178
ovarian follicle rupture GO:0001543 2 0.177
regulation of glucose metabolic process GO:0010906 60 0.175
rhythmic process GO:0048511 174 0.174
response to organic cyclic compound GO:0014070 198 0.168
cell adhesion GO:0007155 329 0.162
membrane lipid metabolic process GO:0006643 53 0.158
development of primary female sexual characteristics GO:0046545 73 0.157
regulation of plasminogen activation GO:0010755 4 0.154
female sex differentiation GO:0046660 84 0.152
monosaccharide metabolic process GO:0005996 106 0.151
muscle contraction GO:0006936 101 0.150
organic hydroxy compound metabolic process GO:1901615 203 0.148
regulation of protein processing GO:0070613 96 0.147
Human
regulation of transferase activity GO:0051338 263 0.146
regulation of homeostatic process GO:0032844 182 0.145
Human
negative regulation of protein metabolic process GO:0051248 282 0.144
Human
peptidyl amino acid modification GO:0018193 336 0.143
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.141
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.140
naphthalene metabolic process GO:0018931 1 0.140
regulation of carbohydrate biosynthetic process GO:0043255 40 0.137
astrocyte differentiation GO:0048708 43 0.137
Human
epithelial tube morphogenesis GO:0060562 303 0.133
fat soluble vitamin metabolic process GO:0006775 11 0.133
zymogen activation GO:0031638 41 0.133
regulation of cholesterol metabolic process GO:0090181 14 0.131
renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure GO:0003072 5 0.129
mapk cascade GO:0000165 281 0.129
fat soluble vitamin biosynthetic process GO:0042362 4 0.126
cell substrate adhesion GO:0031589 130 0.126
ceramide metabolic process GO:0006672 31 0.125
fatty acid metabolic process GO:0006631 121 0.125
regulation of secretion by cell GO:1903530 249 0.124
blood vessel morphogenesis GO:0048514 285 0.122
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.119
regulation of blood vessel size GO:0050880 56 0.118
response to oxygen levels GO:0070482 62 0.118
response to metal ion GO:0010038 47 0.117
ossification GO:0001503 216 0.116
regulation of systemic arterial blood pressure GO:0003073 61 0.114
muscle system process GO:0003012 141 0.114
ovulation cycle GO:0042698 59 0.111
regulation of protein kinase activity GO:0045859 232 0.110
hepaticobiliary system development GO:0061008 67 0.109
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.108
cellular homeostasis GO:0019725 240 0.107
Human
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 13 0.106
endocrine process GO:0050886 39 0.106
vitamin d biosynthetic process GO:0042368 3 0.106
triglyceride rich lipoprotein particle remodeling GO:0034370 2 0.106
immune effector process GO:0002252 321 0.106
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.104
defense response to other organism GO:0098542 197 0.103
organelle assembly GO:0070925 177 0.100
positive regulation of peptide secretion GO:0002793 33 0.100
complement activation GO:0006956 16 0.100
regulation of lipoprotein lipase activity GO:0051004 4 0.100
endocrine system development GO:0035270 98 0.099
ear development GO:0043583 200 0.098
positive regulation of kinase activity GO:0033674 155 0.096
organic hydroxy compound biosynthetic process GO:1901617 77 0.096
response to stilbenoid GO:0035634 22 0.095
lipid transport GO:0006869 98 0.095
response to decreased oxygen levels GO:0036293 59 0.095
maintenance of location GO:0051235 89 0.095
negative regulation of endopeptidase activity GO:0010951 44 0.094
alpha amino acid biosynthetic process GO:1901607 15 0.093
regulation of establishment of protein localization GO:0070201 181 0.093
skeletal system morphogenesis GO:0048705 203 0.093
regulation of endopeptidase activity GO:0052548 89 0.093
negative regulation of cell proliferation GO:0008285 296 0.092
positive regulation of hormone secretion GO:0046887 38 0.092
angiogenesis GO:0001525 201 0.092
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.092
opsonization GO:0008228 3 0.090
positive regulation of activation of membrane attack complex GO:0001970 2 0.089
regulation of apoptotic signaling pathway GO:2001233 197 0.089
cellular response to inorganic substance GO:0071241 37 0.089
organ growth GO:0035265 117 0.089
humoral immune response GO:0006959 57 0.088
vascular process in circulatory system GO:0003018 62 0.088
positive regulation of transferase activity GO:0051347 167 0.087
collagen fibril organization GO:0030199 32 0.086
peptidyl serine modification GO:0018209 83 0.086
negative regulation of epithelial cell proliferation GO:0050680 64 0.085
regulation of carbohydrate metabolic process GO:0006109 75 0.085
liver development GO:0001889 66 0.084
unsaturated fatty acid metabolic process GO:0033559 31 0.084
negative regulation of response to wounding GO:1903035 77 0.084
Human Mouse
tissue remodeling GO:0048771 102 0.083
vitamin d3 metabolic process GO:0070640 3 0.083
regulation of plasma lipoprotein particle levels GO:0097006 23 0.083
female gonad development GO:0008585 71 0.083
organonitrogen compound biosynthetic process GO:1901566 192 0.083
cell differentiation involved in embryonic placenta development GO:0060706 26 0.081
renal tubule morphogenesis GO:0061333 72 0.081
cellular response to organic cyclic compound GO:0071407 87 0.081
regulation of steroid metabolic process GO:0019218 39 0.079
spermatogenesis GO:0007283 284 0.078
negative regulation of peptidase activity GO:0010466 46 0.078
regulation of tube size GO:0035150 57 0.078
cholesterol esterification GO:0034435 3 0.077
cell matrix adhesion GO:0007160 68 0.076
cell type specific apoptotic process GO:0097285 268 0.075
fatty acid biosynthetic process GO:0006633 41 0.074
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.074
protein secretion GO:0009306 111 0.074
cholesterol homeostasis GO:0042632 44 0.073
regulation of peptidase activity GO:0052547 96 0.072
epithelium migration GO:0090132 63 0.072
hormone secretion GO:0046879 128 0.072
negative regulation of protein maturation GO:1903318 79 0.072
Human
hormone metabolic process GO:0042445 86 0.071
glycerolipid catabolic process GO:0046503 16 0.071
negative regulation of carbohydrate metabolic process GO:0045912 19 0.071
regulation of protein kinase c activity GO:1900019 1 0.070
positive regulation of organ growth GO:0046622 29 0.070
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 15 0.070
long chain fatty acid metabolic process GO:0001676 26 0.070
regulation of renal output by angiotensin GO:0002019 2 0.069
morphogenesis of a branching epithelium GO:0061138 193 0.069
regulation of coagulation GO:0050818 31 0.069
Human Mouse
sterol transport GO:0015918 38 0.068
cellular response to insulin stimulus GO:0032869 78 0.068
glial cell differentiation GO:0010001 131 0.068
Human
positive regulation of cell adhesion GO:0045785 80 0.068
mesonephros development GO:0001823 97 0.067
cellular metal ion homeostasis GO:0006875 151 0.066
Human
cellular ion homeostasis GO:0006873 165 0.066
Human
positive regulation of protein kinase activity GO:0045860 144 0.065
placenta development GO:0001890 140 0.065
cellular chemical homeostasis GO:0055082 215 0.064
Human
lipid catabolic process GO:0016042 69 0.064
negative regulation of cellular protein metabolic process GO:0032269 247 0.064
Human
mesonephric tubule development GO:0072164 94 0.064
plasma lipoprotein particle organization GO:0071827 11 0.064
labyrinthine layer development GO:0060711 49 0.064
response to phenylpropanoid GO:0080184 22 0.063
skeletal muscle organ development GO:0060538 163 0.063
regulation of lipid transport GO:0032368 36 0.063
regulation of leukocyte mediated immunity GO:0002703 104 0.063
regulation of ossification GO:0030278 112 0.063
endocytosis GO:0006897 168 0.062
response to inorganic substance GO:0010035 96 0.062
trophoblast giant cell differentiation GO:0060707 15 0.062
carbohydrate homeostasis GO:0033500 128 0.062
positive regulation of secretion by cell GO:1903532 114 0.062
regulation of cytokine production GO:0001817 266 0.062
anatomical structure homeostasis GO:0060249 145 0.061
renal tubule development GO:0061326 87 0.061
nephron epithelium morphogenesis GO:0072088 68 0.061
positive regulation of secretion GO:0051047 130 0.061
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.060
innate immune response GO:0045087 157 0.060
lipid storage GO:0019915 36 0.060
glial cell development GO:0021782 54 0.060
b cell mediated immunity GO:0019724 71 0.060
nucleobase containing small molecule metabolic process GO:0055086 352 0.059
cellular lipid catabolic process GO:0044242 52 0.058
kidney development GO:0001822 213 0.058
glucocorticoid metabolic process GO:0008211 9 0.058
multicellular organismal macromolecule metabolic process GO:0044259 19 0.057
Human
chemotaxis GO:0006935 247 0.057
bone development GO:0060348 120 0.057
regulation of cell motility GO:2000145 236 0.057
very low density lipoprotein particle remodeling GO:0034372 1 0.056
development of primary sexual characteristics GO:0045137 143 0.056
positive regulation of protein modification process GO:0031401 299 0.056
Human
renal system process GO:0003014 48 0.056
response to acid chemical GO:0001101 111 0.056
positive regulation of mapk cascade GO:0043410 170 0.055
plasminogen activation GO:0031639 7 0.055
regulation of endocytosis GO:0030100 69 0.055
renin angiotensin regulation of aldosterone production GO:0002018 3 0.055
retinoid metabolic process GO:0001523 24 0.055
positive regulation of protein activation cascade GO:2000259 2 0.054
regulation of anatomical structure size GO:0090066 178 0.054
protein lipid complex remodeling GO:0034368 6 0.054
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.054
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.054
adiponectin activated signaling pathway GO:0033211 4 0.053
dna metabolic process GO:0006259 303 0.053
monocarboxylic acid biosynthetic process GO:0072330 61 0.053
ureteric bud development GO:0001657 94 0.053
regulation of cell cycle GO:0051726 281 0.052
regulation of blood pressure GO:0008217 93 0.052
gonad development GO:0008406 141 0.052
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.052
cellular alcohol metabolic process GO:0044107 3 0.052
metal ion homeostasis GO:0055065 189 0.052
Human
nephron tubule morphogenesis GO:0072078 68 0.052
hepatocyte growth factor receptor signaling pathway GO:0048012 3 0.052
regulation of lymphocyte mediated immunity GO:0002706 84 0.051
glycoprotein metabolic process GO:0009100 116 0.051
leukocyte differentiation GO:0002521 342 0.051
regulation of neuron death GO:1901214 134 0.051
reactive nitrogen species metabolic process GO:2001057 0 0.051
cellular response to lipid GO:0071396 145 0.051
branching involved in ureteric bud morphogenesis GO:0001658 56 0.051
organonitrogen compound catabolic process GO:1901565 264 0.051
kidney epithelium development GO:0072073 121 0.050
striated muscle tissue development GO:0014706 293 0.050
regulation of lipid biosynthetic process GO:0046890 54 0.049
muscle tissue development GO:0060537 308 0.049
collagen biosynthetic process GO:0032964 7 0.048
Human
cellular divalent inorganic cation homeostasis GO:0072503 127 0.047
Human
epithelial cell proliferation GO:0050673 174 0.047
myeloid leukocyte differentiation GO:0002573 119 0.047
cellular calcium ion homeostasis GO:0006874 119 0.046
Human
regulation of vasculature development GO:1901342 88 0.046
embryonic placenta development GO:0001892 98 0.046
cell fate commitment GO:0045165 210 0.046
regulation of peptide secretion GO:0002791 77 0.046
axonogenesis GO:0007409 274 0.045
divalent inorganic cation transport GO:0072511 178 0.045
Human
regulation of protein localization GO:0032880 231 0.045
regulation of osteoblast differentiation GO:0045667 67 0.045
positive regulation of phagocytosis GO:0050766 26 0.044
astrocyte activation GO:0048143 2 0.044
artery development GO:0060840 53 0.044
stem cell differentiation GO:0048863 268 0.044
morphogenesis of a branching structure GO:0001763 203 0.044
negative regulation of cellular carbohydrate metabolic process GO:0010677 19 0.044
calcitriol biosynthetic process from calciol GO:0036378 3 0.044
regulation of complement activation GO:0030449 7 0.044
tissue migration GO:0090130 68 0.044
cellular response to cadmium ion GO:0071276 3 0.043
protein catabolic process GO:0030163 221 0.043
regulation of defense response GO:0031347 233 0.043
actomyosin structure organization GO:0031032 56 0.043
vitamin metabolic process GO:0006766 23 0.043
cholesterol transport GO:0030301 38 0.043
arachidonic acid metabolic process GO:0019369 14 0.043
organelle localization GO:0051640 179 0.043
regulation of blood vessel size by renin angiotensin GO:0002034 5 0.043
positive regulation of growth GO:0045927 104 0.042
triglyceride catabolic process GO:0019433 9 0.042
regulation of neuron apoptotic process GO:0043523 122 0.042
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 6 0.042
response to chromate GO:0046687 1 0.042
positive regulation of protein transport GO:0051222 93 0.042
cellular biogenic amine metabolic process GO:0006576 28 0.042
bone morphogenesis GO:0060349 78 0.041
multicellular organismal homeostasis GO:0048871 164 0.041
cation transport GO:0006812 399 0.041
Human
activation of membrane attack complex GO:0001905 4 0.041
lipoprotein biosynthetic process GO:0042158 33 0.041
response to insulin GO:0032868 100 0.041
diterpenoid metabolic process GO:0016101 24 0.041
regulation of lipoprotein metabolic process GO:0050746 4 0.040
negative regulation of lipid metabolic process GO:0045833 30 0.040
lymphocyte mediated immunity GO:0002449 139 0.040
folic acid containing compound metabolic process GO:0006760 3 0.040
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 11 0.040
epithelial cell development GO:0002064 159 0.040
inner ear receptor cell differentiation GO:0060113 61 0.040
chromatin organization GO:0006325 206 0.040
low density lipoprotein particle remodeling GO:0034374 2 0.040
negative regulation of complement activation GO:0045916 3 0.040
porphyrin containing compound metabolic process GO:0006778 22 0.040
plasma membrane long chain fatty acid transport GO:0015911 1 0.040
alpha amino acid metabolic process GO:1901605 59 0.039
regulation of fatty acid biosynthetic process GO:0042304 12 0.039
regulation of tissue remodeling GO:0034103 38 0.039
regionalization GO:0003002 337 0.039
nucleoside triphosphate metabolic process GO:0009141 230 0.039
neuron migration GO:0001764 122 0.039
regulation of cellular response to growth factor stimulus GO:0090287 82 0.038
cardiac muscle tissue development GO:0048738 130 0.038
positive regulation of protein maturation GO:1903319 7 0.038
labyrinthine layer blood vessel development GO:0060716 21 0.038
glycoprotein biosynthetic process GO:0009101 89 0.038
glucose homeostasis GO:0042593 128 0.038
regulation of reactive oxygen species metabolic process GO:2000377 40 0.037
Human
small molecule catabolic process GO:0044282 71 0.037
lipoprotein catabolic process GO:0042159 7 0.037
reactive oxygen species biosynthetic process GO:1903409 8 0.037
connective tissue development GO:0061448 179 0.037
regulation of vesicle mediated transport GO:0060627 139 0.037
positive regulation of apoptotic process GO:0043065 217 0.037
urogenital system development GO:0001655 261 0.037
inositol lipid mediated signaling GO:0048017 41 0.036
hexose biosynthetic process GO:0019319 39 0.036
steroid esterification GO:0034433 3 0.036
purine containing compound metabolic process GO:0072521 311 0.036
ameboidal type cell migration GO:0001667 128 0.036
camera type eye development GO:0043010 266 0.036
cytokine production GO:0001816 319 0.036
multi multicellular organism process GO:0044706 109 0.036
monocarboxylic acid catabolic process GO:0072329 27 0.035
regulation of adaptive immune response GO:0002819 90 0.035
adaptive immune response GO:0002250 155 0.035
regulation of organ growth GO:0046620 61 0.035
inner ear morphogenesis GO:0042472 101 0.035
regulation of protein secretion GO:0050708 82 0.035
sensory perception GO:0007600 245 0.035
response to organonitrogen compound GO:0010243 246 0.035
muscle cell proliferation GO:0033002 52 0.035
cell growth GO:0016049 130 0.035
response to testosterone GO:0033574 3 0.035
female gamete generation GO:0007292 74 0.035
ketone body biosynthetic process GO:0046951 1 0.034
negative regulation of endothelial cell migration GO:0010596 4 0.034
calcium ion homeostasis GO:0055074 127 0.034
Human
cellular response to growth factor stimulus GO:0071363 197 0.034
cellular response to metal ion GO:0071248 31 0.034
multicellular organismal metabolic process GO:0044236 28 0.034
Human
organ regeneration GO:0031100 2 0.034
positive regulation of cytokine production GO:0001819 174 0.034
fatty acid transmembrane transport GO:1902001 1 0.034
steroid biosynthetic process GO:0006694 47 0.033
regulation of kinase activity GO:0043549 249 0.033
ras protein signal transduction GO:0007265 77 0.033
endothelial cell migration GO:0043542 44 0.033
high density lipoprotein particle remodeling GO:0034375 4 0.033
cardiac chamber morphogenesis GO:0003206 93 0.033
protein activation cascade GO:0072376 19 0.033
gluconeogenesis GO:0006094 39 0.033
cartilage development GO:0051216 140 0.033
phagocytosis GO:0006909 66 0.033
nephron development GO:0072006 109 0.033
regulation of mapk cascade GO:0043408 248 0.033
muscle cell development GO:0055001 133 0.032
ureteric bud morphogenesis GO:0060675 62 0.032
response to estrogen GO:0043627 24 0.032
positive regulation of leukocyte mediated immunity GO:0002705 70 0.032
ovulation GO:0030728 15 0.032
negative regulation of ossification GO:0030279 49 0.032
positive regulation of programmed cell death GO:0043068 218 0.032
respiratory system development GO:0060541 190 0.032
acetylcholine catabolic process GO:0006581 1 0.031
carboxylic acid catabolic process GO:0046395 51 0.031
gliogenesis GO:0042063 141 0.031
Human
platelet activation GO:0030168 40 0.031
positive regulation of coagulation GO:0050820 13 0.031
Human
neuron death GO:0070997 154 0.031
negative regulation of cell cycle GO:0045786 123 0.031
response to growth factor GO:0070848 198 0.031
cellular component assembly involved in morphogenesis GO:0010927 139 0.031
chondrocyte development GO:0002063 24 0.030
very long chain fatty acid catabolic process GO:0042760 2 0.030
learning or memory GO:0007611 148 0.030
negative regulation of cell growth GO:0030308 44 0.030
regulation of cell shape GO:0008360 39 0.030
branching morphogenesis of an epithelial tube GO:0048754 159 0.030
meiotic cell cycle GO:0051321 122 0.030
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.030
acute inflammatory response GO:0002526 41 0.030
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.030
skin development GO:0043588 220 0.030
heterocycle catabolic process GO:0046700 280 0.029
regulation of peptide transport GO:0090087 91 0.029
multicellular organism growth GO:0035264 161 0.029
kidney morphogenesis GO:0060993 83 0.029
heart process GO:0003015 94 0.029
negative regulation of blood vessel morphogenesis GO:2000181 25 0.029
limb development GO:0060173 166 0.029
short chain fatty acid catabolic process GO:0019626 2 0.029
pallium development GO:0021543 120 0.029
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.029
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 22 0.029
learning GO:0007612 98 0.029
organic cyclic compound catabolic process GO:1901361 295 0.029
regulation of cell adhesion GO:0030155 154 0.029
bmp signaling pathway GO:0030509 93 0.029
response to peptide hormone GO:0043434 127 0.029
embryonic appendage morphogenesis GO:0035113 126 0.028
negative regulation of protein activation cascade GO:2000258 3 0.028
nucleotide metabolic process GO:0009117 332 0.028
response to osmotic stress GO:0006970 21 0.028
endothelium development GO:0003158 45 0.028
sulfur compound metabolic process GO:0006790 100 0.028
negative regulation of serine type endopeptidase activity GO:1900004 2 0.028
response to nutrient levels GO:0031667 109 0.028
cell killing GO:0001906 67 0.028
macromolecular complex remodeling GO:0034367 6 0.028
regulation of lipid metabolic process GO:0019216 118 0.028
positive regulation of fatty acid metabolic process GO:0045923 8 0.028
biomineral tissue development GO:0031214 64 0.028
positive regulation of protein phosphorylation GO:0001934 242 0.028
Human
phasic smooth muscle contraction GO:0014821 8 0.027
dna endoreduplication GO:0042023 4 0.027
locomotory behavior GO:0007626 195 0.027
palate development GO:0060021 76 0.027
negative regulation of apoptotic signaling pathway GO:2001234 104 0.027
positive regulation of adaptive immune response GO:0002821 61 0.027
cellular response to peptide hormone stimulus GO:0071375 92 0.027
regulation of cytokine secretion GO:0050707 61 0.027
blood vessel endothelial cell migration GO:0043534 23 0.027
positive regulation of blood pressure GO:0045777 21 0.027
response to steroid hormone GO:0048545 56 0.027
protein glycosylation GO:0006486 55 0.026
immunoglobulin mediated immune response GO:0016064 69 0.026
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.026
organelle fission GO:0048285 170 0.026
exocrine system development GO:0035272 45 0.026
positive regulation of macrophage derived foam cell differentiation GO:0010744 4 0.026
acylglycerol catabolic process GO:0046464 11 0.026
striated muscle cell development GO:0055002 125 0.026
naphthalene containing compound metabolic process GO:0090420 1 0.026
regulation of fatty acid metabolic process GO:0019217 28 0.026

F2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.335
immune system disease DOID:2914 0 0.242
Human
disease of anatomical entity DOID:7 0 0.242
Human
blood coagulation disease DOID:1247 0 0.136
Human
inherited blood coagulation disease DOID:2214 0 0.136
hematopoietic system disease DOID:74 0 0.136
Human
inherited metabolic disorder DOID:655 0 0.113
nervous system disease DOID:863 0 0.087
alpha 1 antitrypsin deficiency DOID:13372 0 0.070
plasma protein metabolism disease DOID:2345 0 0.070
acquired metabolic disease DOID:0060158 0 0.042