|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.560
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.546
|
Zebrafish |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.523
|
Zebrafish |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.491
|
Rat |
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.434
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.418
|
Zebrafish |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.405
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.371
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.366
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.359
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.348
|
Rat |
|
|
gland development
|
GO:0048732 |
330 |
0.341
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.340
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.332
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.320
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.318
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.306
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.287
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.283
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.278
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.263
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.261
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.259
|
Rat |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.258
|
Rat |
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.254
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.250
|
Human |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.245
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.245
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.242
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.238
|
Human |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.238
|
Human |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.237
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.232
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.224
|
Human |
|
|
response to alcohol
|
GO:0097305 |
48 |
0.223
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.221
|
Rat |
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.220
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.219
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.215
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.211
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.204
|
Zebrafish |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.201
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.198
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.198
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.198
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.196
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.196
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.196
|
Mouse |
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.195
|
Rat |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.195
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.193
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.192
|
Mouse |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.188
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.187
|
Mouse |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.183
|
Rat |
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.181
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.174
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.172
|
Human |
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.171
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.171
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.171
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.169
|
Human |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.169
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.168
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.166
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.161
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.161
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.160
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.159
|
Human Rat |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.158
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.158
|
Mouse |
|
|
adherens junction organization
|
GO:0034332 |
28 |
0.156
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.155
|
Human |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.155
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.155
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.155
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.152
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.151
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.151
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.151
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.150
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.150
|
Mouse |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.148
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.145
|
Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.144
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.144
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.142
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.141
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.141
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.139
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.139
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.138
|
Mouse |
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.138
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.137
|
Mouse |
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.137
|
Human |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.136
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.135
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.135
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.134
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.134
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.134
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.133
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.133
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.131
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.130
|
Human |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.130
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.130
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.129
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.128
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.126
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.126
|
Rat |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.126
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.126
|
Human Rat |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.126
|
Human |
|
|
muscle system process
|
GO:0003012 |
141 |
0.123
|
Rat |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.123
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.121
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.121
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.120
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.119
|
Rat |
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.118
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.118
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.117
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.117
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.117
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.116
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.115
|
Rat |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.115
|
Zebrafish |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.115
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.115
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.115
|
Zebrafish |
|
|
coagulation
|
GO:0050817 |
78 |
0.114
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.113
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.112
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.112
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.109
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.109
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.109
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.109
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.107
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.106
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.106
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.104
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.103
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.103
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.103
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.102
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.101
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.101
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.099
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.098
|
Mouse |
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.098
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.097
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.097
|
Mouse |
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.096
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.096
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.095
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.095
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.094
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
50 |
0.094
|
Zebrafish |
|
|
forebrain development
|
GO:0030900 |
302 |
0.093
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.092
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.092
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.090
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.090
|
Rat |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.090
|
Human |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.088
|
|
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.088
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.087
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.087
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.087
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.086
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.086
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.086
|
Mouse |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.085
|
|
|
|
ureteric bud morphogenesis
|
GO:0060675 |
62 |
0.084
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.083
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.083
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.083
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.082
|
|
|
|
nephron tubule development
|
GO:0072080 |
84 |
0.082
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.081
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.081
|
Mouse |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.081
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.081
|
Rat |
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.081
|
|
|
|
nephron epithelium development
|
GO:0072009 |
92 |
0.080
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.080
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.079
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.079
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.078
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.078
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.078
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.078
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.077
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.077
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
30 |
0.077
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.076
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.076
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.075
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.075
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.075
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.075
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.075
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.074
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
83 |
0.074
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.074
|
|
|
|
renal tubule development
|
GO:0061326 |
87 |
0.074
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.074
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
28 |
0.073
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.073
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.072
|
|
|
|
female gonad development
|
GO:0008585 |
71 |
0.072
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.072
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.071
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.071
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.071
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.071
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.071
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.071
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.070
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.070
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.069
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.069
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.069
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.069
|
Human |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.068
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
23 |
0.067
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
72 |
0.067
|
|
|
|
cell cell adhesion
|
GO:0098609 |
41 |
0.067
|
|
|
|
mesonephric tubule morphogenesis
|
GO:0072171 |
63 |
0.067
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.066
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.066
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.066
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.066
|
Human |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.066
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.065
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.065
|
Rat |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.065
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.064
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.064
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.064
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.064
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.064
|
|
|
|
positive regulation of heart rate by epinephrine norepinephrine
|
GO:0001996 |
4 |
0.063
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.063
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.063
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.063
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.063
|
Human |
|
|
regulation of catenin import into nucleus
|
GO:0035412 |
5 |
0.062
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.062
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.062
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
46 |
0.062
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.061
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.061
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.061
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.061
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.060
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.060
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.060
|
Mouse |
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.060
|
Rat |
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.059
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.059
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.059
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.059
|
|
|
|
chondrocyte development
|
GO:0002063 |
24 |
0.059
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.059
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.059
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.059
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.059
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.058
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.058
|
Human Rat |
|
|
immune effector process
|
GO:0002252 |
321 |
0.058
|
Mouse |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.058
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.058
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.057
|
Rat |
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
68 |
0.057
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.057
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.057
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.057
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.057
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.057
|
Mouse |
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.057
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.057
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.057
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.057
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.056
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.056
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.056
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.056
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
94 |
0.055
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.055
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.055
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.055
|
Mouse |
|
|
cation transport
|
GO:0006812 |
399 |
0.055
|
Human Rat |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.055
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.054
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.054
|
Zebrafish |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.054
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.054
|
Rat |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.054
|
Rat |
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.053
|
Rat |
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.053
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.053
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.053
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.053
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.053
|
Human |
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.052
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.052
|
Rat |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.052
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.052
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.052
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.052
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.052
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.052
|
Mouse |
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
51 |
0.052
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.051
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.051
|
Human |
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.051
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
47 |
0.050
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.050
|
|
|
|
cardiac muscle tissue morphogenesis
|
GO:0055008 |
44 |
0.050
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.050
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.050
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.050
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.049
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.049
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.049
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.049
|
|
|
|
retina vasculature development in camera type eye
|
GO:0061298 |
17 |
0.049
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.048
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.048
|
Rat |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.048
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.048
|
Mouse |
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.048
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.047
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
61 |
0.047
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.047
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.047
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.047
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.047
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.047
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.046
|
Mouse |
|
|
response to superoxide
|
GO:0000303 |
16 |
0.046
|
|
|
|
metanephros development
|
GO:0001656 |
79 |
0.046
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.046
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.046
|
|
|
|
myofibril assembly
|
GO:0030239 |
34 |
0.046
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.046
|
Mouse |
|
|
endothelium development
|
GO:0003158 |
45 |
0.046
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.046
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.046
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.046
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.046
|
Human |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.046
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.045
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.045
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.045
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.045
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.045
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.045
|
Rat |
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.045
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.045
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.045
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.045
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.045
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.045
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.044
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.044
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.044
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.044
|
Human |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.044
|
Mouse |
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.044
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
22 |
0.044
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.043
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.043
|
Rat |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.043
|
|
|
|
regulation of glucose transport
|
GO:0010827 |
32 |
0.043
|
Mouse |
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.043
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.043
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.043
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.043
|
|
|
|
muscle tissue morphogenesis
|
GO:0060415 |
53 |
0.043
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.042
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.042
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.042
|
|
|
|
mesonephros development
|
GO:0001823 |
97 |
0.042
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.042
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.042
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.042
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.042
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.042
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.042
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.041
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.041
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.041
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.041
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.041
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.041
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
69 |
0.041
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.041
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.041
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.040
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.040
|
Mouse |
|
|
negative regulation of catenin import into nucleus
|
GO:0035414 |
2 |
0.040
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.040
|
|
|
|
salivary gland development
|
GO:0007431 |
37 |
0.040
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.040
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
3 |
0.040
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.040
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.040
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.039
|
|
|
|
pigmentation
|
GO:0043473 |
71 |
0.039
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.039
|
Mouse |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.039
|
Human |
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.039
|
Human |
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.039
|
Human |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.039
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.039
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.039
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.039
|
|
|
|
blood vessel remodeling
|
GO:0001974 |
33 |
0.038
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.038
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.038
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.038
|
|
|
|
response to vitamin d
|
GO:0033280 |
3 |
0.038
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.037
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.037
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.037
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.037
|
|
|
|
regulation of tight junction assembly
|
GO:2000810 |
2 |
0.037
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.037
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.037
|
Human |
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.037
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.037
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
27 |
0.037
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.037
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.037
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.037
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.036
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.036
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.036
|
Human |
|
|
eye photoreceptor cell development
|
GO:0042462 |
31 |
0.036
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.036
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.036
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.036
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.036
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.036
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.036
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.036
|
|
|
|
negative regulation of alcohol biosynthetic process
|
GO:1902931 |
4 |
0.036
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.035
|
Mouse |
|
|
compound eye development
|
GO:0048749 |
1 |
0.035
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.035
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.035
|
|
|
|
regulation of engulfment of apoptotic cell
|
GO:1901074 |
2 |
0.035
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.035
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.035
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.035
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.035
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.035
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.035
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.034
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.034
|
Human |
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.034
|
Rat |
|
|
inner ear receptor cell differentiation
|
GO:0060113 |
61 |
0.034
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.034
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.034
|
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.034
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.034
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.033
|
|
|
|
ovarian follicle development
|
GO:0001541 |
40 |
0.033
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.033
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.033
|
Human |
|
|
cell migration involved in gastrulation
|
GO:0042074 |
13 |
0.033
|
|
|
|
neural crest cell differentiation
|
GO:0014033 |
54 |
0.033
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.033
|
Mouse |
|
|
b cell activation
|
GO:0042113 |
161 |
0.033
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.033
|
|
|
|
response to x ray
|
GO:0010165 |
11 |
0.033
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.033
|
|
|
|
bone mineralization
|
GO:0030282 |
54 |
0.033
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.032
|
|
|
|
aminoglycan metabolic process
|
GO:0006022 |
34 |
0.032
|
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
45 |
0.032
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.032
|
|
|
|
cellular response to gamma radiation
|
GO:0071480 |
4 |
0.032
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.032
|
|
|
|
somite development
|
GO:0061053 |
81 |
0.032
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.032
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.032
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.032
|
|
