Mus musculus

67 known processes

Fancc

Fanconi anemia, complementation group C

(Aliases: Facc,BB116513)

Fancc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.452
cellular response to dna damage stimulus GO:0006974 207 0.217
regulation of cellular amine metabolic process GO:0033238 20 0.193
amine metabolic process GO:0009308 45 0.190
cellular amine metabolic process GO:0044106 44 0.172
dna repair GO:0006281 107 0.140
macromolecule catabolic process GO:0009057 281 0.132
cellular amino acid metabolic process GO:0006520 103 0.131
response to radiation GO:0009314 165 0.120
regulation of cellular amino acid metabolic process GO:0006521 5 0.113
cellular ketone metabolic process GO:0042180 84 0.106
immune effector process GO:0002252 321 0.103
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.094
leukocyte differentiation GO:0002521 342 0.092
positive regulation of cellular amine metabolic process GO:0033240 5 0.092
organic anion transport GO:0015711 137 0.090
actin cytoskeleton organization GO:0030036 220 0.090
germ cell development GO:0007281 185 0.089
ribonucleotide metabolic process GO:0009259 291 0.088
regulation of cell cycle GO:0051726 281 0.088
spermatogenesis GO:0007283 284 0.083
positive regulation of protein phosphorylation GO:0001934 242 0.082
reactive oxygen species metabolic process GO:0072593 84 0.081
negative regulation of cell proliferation GO:0008285 296 0.081
nucleotide metabolic process GO:0009117 332 0.078
nucleoside phosphate metabolic process GO:0006753 338 0.078
purine containing compound metabolic process GO:0072521 311 0.077
aromatic compound catabolic process GO:0019439 286 0.076
regulation of reactive oxygen species metabolic process GO:2000377 40 0.075
regulation of hydrolase activity GO:0051336 246 0.073
regulation of cellular catabolic process GO:0031329 242 0.072
purine ribonucleotide metabolic process GO:0009150 290 0.071
organic cyclic compound catabolic process GO:1901361 295 0.070
cellular nitrogen compound catabolic process GO:0044270 280 0.067
response to organonitrogen compound GO:0010243 246 0.065
cell adhesion GO:0007155 329 0.064
purine nucleotide metabolic process GO:0006163 302 0.064
nucleoside triphosphate metabolic process GO:0009141 230 0.064
nucleoside metabolic process GO:0009116 246 0.063
apoptotic signaling pathway GO:0097190 306 0.063
regulation of membrane potential GO:0042391 192 0.062
peptidyl amino acid modification GO:0018193 336 0.062
gtp metabolic process GO:0046039 144 0.062
heterocycle catabolic process GO:0046700 280 0.059
male gamete generation GO:0048232 285 0.059
organonitrogen compound catabolic process GO:1901565 264 0.058
purine nucleoside metabolic process GO:0042278 241 0.058
regulation of organelle organization GO:0033043 289 0.057
nucleobase containing small molecule metabolic process GO:0055086 352 0.057
carbohydrate derivative catabolic process GO:1901136 231 0.057
negative regulation of phosphorylation GO:0042326 166 0.056
regulation of cellular response to stress GO:0080135 159 0.056
ras protein signal transduction GO:0007265 77 0.054
regulation of cellular component biogenesis GO:0044087 181 0.053
inflammatory response GO:0006954 244 0.053
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.052
innate immune response GO:0045087 157 0.052
glycosyl compound metabolic process GO:1901657 246 0.052
cellular response to radiation GO:0071478 28 0.052
multicellular organism growth GO:0035264 161 0.051
positive regulation of programmed cell death GO:0043068 218 0.051
cellular response to oxidative stress GO:0034599 76 0.051
defense response to other organism GO:0098542 197 0.051
t cell differentiation GO:0030217 174 0.051
b cell activation GO:0042113 161 0.050
response to organic cyclic compound GO:0014070 198 0.050
transmembrane transport GO:0055085 412 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.049
response to light stimulus GO:0009416 135 0.048
response to lipopolysaccharide GO:0032496 128 0.048
ribonucleoside triphosphate metabolic process GO:0009199 220 0.047
positive regulation of cell death GO:0010942 224 0.047
ribonucleotide catabolic process GO:0009261 208 0.047
negative regulation of cellular amine metabolic process GO:0033239 1 0.047
ribonucleoside catabolic process GO:0042454 206 0.046
lymphocyte activation involved in immune response GO:0002285 93 0.046
purine nucleoside triphosphate catabolic process GO:0009146 203 0.045
action potential GO:0001508 78 0.045
ribose phosphate metabolic process GO:0019693 291 0.044
membrane organization GO:0061024 245 0.044
camera type eye development GO:0043010 266 0.044
regulation of lymphocyte differentiation GO:0045619 107 0.044
purine nucleoside catabolic process GO:0006152 205 0.043
purine ribonucleoside catabolic process GO:0046130 205 0.043
rho protein signal transduction GO:0007266 32 0.043
leukocyte activation involved in immune response GO:0002366 126 0.042
mitotic cell cycle GO:0000278 195 0.042
purine nucleoside triphosphate metabolic process GO:0009144 226 0.042
positive regulation of protein modification process GO:0031401 299 0.041
regulation of protein kinase activity GO:0045859 232 0.041
synaptic transmission GO:0007268 329 0.041
cellular response to cytokine stimulus GO:0071345 189 0.041
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.041
response to oxidative stress GO:0006979 123 0.040
regulation of inflammatory response GO:0050727 147 0.040
purine ribonucleotide catabolic process GO:0009154 208 0.040
organonitrogen compound biosynthetic process GO:1901566 192 0.040
nucleoside catabolic process GO:0009164 206 0.039
protein processing GO:0016485 163 0.039
organelle assembly GO:0070925 177 0.039
wound healing GO:0042060 157 0.039
protein maturation GO:0051604 176 0.039
embryonic organ morphogenesis GO:0048562 276 0.039
negative regulation of phosphorus metabolic process GO:0010563 184 0.038
lymphocyte differentiation GO:0030098 242 0.038
signal transduction involved in dna damage checkpoint GO:0072422 3 0.038
nucleotide catabolic process GO:0009166 217 0.038
developmental maturation GO:0021700 193 0.038
cellular response to light stimulus GO:0071482 19 0.038
activation of immune response GO:0002253 138 0.037
homeostasis of number of cells GO:0048872 210 0.037
positive regulation of hydrolase activity GO:0051345 148 0.037
ribonucleoside metabolic process GO:0009119 245 0.037
positive regulation of apoptotic process GO:0043065 217 0.037
cellular protein catabolic process GO:0044257 155 0.036
protein catabolic process GO:0030163 221 0.036
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
negative regulation of phosphate metabolic process GO:0045936 184 0.036
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.035
transmission of nerve impulse GO:0019226 76 0.035
regulation of protein localization GO:0032880 231 0.035
regulation of defense response GO:0031347 233 0.035
cation transport GO:0006812 399 0.035
regulation of multi organism process GO:0043900 111 0.034
hematopoietic progenitor cell differentiation GO:0002244 143 0.034
negative regulation of protein phosphorylation GO:0001933 126 0.033
purine nucleotide catabolic process GO:0006195 211 0.033
negative regulation of multi organism process GO:0043901 68 0.033
regulation of lymphocyte activation GO:0051249 240 0.032
ribonucleoside triphosphate catabolic process GO:0009203 199 0.032
nucleoside triphosphate catabolic process GO:0009143 205 0.032
organic hydroxy compound metabolic process GO:1901615 203 0.032
regulation of transferase activity GO:0051338 263 0.032
response to extracellular stimulus GO:0009991 127 0.032
regulation of mitotic cell cycle GO:0007346 126 0.031
regulation of leukocyte differentiation GO:1902105 159 0.031
small gtpase mediated signal transduction GO:0007264 97 0.031
cellular response to lipid GO:0071396 145 0.030
regulation of apoptotic signaling pathway GO:2001233 197 0.030
cellular response to abiotic stimulus GO:0071214 56 0.030
regulation of purine nucleotide metabolic process GO:1900542 169 0.030
purine containing compound catabolic process GO:0072523 213 0.030
response to acid chemical GO:0001101 111 0.030
response to inorganic substance GO:0010035 96 0.030
immune response regulating signaling pathway GO:0002764 125 0.030
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.030
cell substrate adhesion GO:0031589 130 0.029
regulation of proteolysis GO:0030162 164 0.029
cell chemotaxis GO:0060326 81 0.029
epithelial tube formation GO:0072175 130 0.029
meiotic cell cycle GO:0051321 122 0.029
anion transport GO:0006820 177 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.029
production of molecular mediator of immune response GO:0002440 103 0.028
cellular response to biotic stimulus GO:0071216 92 0.028
cellular response to lipopolysaccharide GO:0071222 77 0.028
regulation of mapk cascade GO:0043408 248 0.028
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.028
regulation of cytoskeleton organization GO:0051493 122 0.028
regulation of nucleotide metabolic process GO:0006140 169 0.027
regulation of cell migration GO:0030334 219 0.027
cell maturation GO:0048469 127 0.027
regulation of kinase activity GO:0043549 249 0.027
sensory perception GO:0007600 245 0.027
skeletal system development GO:0001501 356 0.027
myeloid cell differentiation GO:0030099 233 0.027
positive regulation of nucleotide metabolic process GO:0045981 114 0.027
positive regulation of cell cycle GO:0045787 92 0.027
cell activation involved in immune response GO:0002263 126 0.027
positive regulation of apoptotic signaling pathway GO:2001235 95 0.027
nuclear division GO:0000280 158 0.027
cytokine production GO:0001816 319 0.027
axonogenesis GO:0007409 274 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.027
positive regulation of proteolysis GO:0045862 85 0.026
respiratory tube development GO:0030323 167 0.026
regulation of mitotic cell cycle phase transition GO:1901990 73 0.026
regulation of establishment of protein localization GO:0070201 181 0.026
compound eye development GO:0048749 1 0.026
negative regulation of immune system process GO:0002683 209 0.026
organelle fission GO:0048285 170 0.026
signal transduction by p53 class mediator GO:0072331 51 0.026
intrinsic apoptotic signaling pathway GO:0097193 132 0.026
chromatin organization GO:0006325 206 0.026
glial cell apoptotic process GO:0034349 3 0.026
meiotic cell cycle process GO:1903046 77 0.025
positive regulation of mapk cascade GO:0043410 170 0.025
response to uv GO:0009411 44 0.025
t cell activation GO:0042110 289 0.025
regulation of t cell proliferation GO:0042129 92 0.025
regulation of protein serine threonine kinase activity GO:0071900 157 0.025
neuronal action potential GO:0019228 54 0.025
positive regulation of cellular catabolic process GO:0031331 148 0.024
lymphocyte proliferation GO:0046651 164 0.024
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.024
cellular component assembly involved in morphogenesis GO:0010927 139 0.024
positive regulation of defense response GO:0031349 124 0.024
anatomical structure homeostasis GO:0060249 145 0.024
b cell differentiation GO:0030183 78 0.024
modification dependent macromolecule catabolic process GO:0043632 133 0.024
regulation of protein complex assembly GO:0043254 83 0.024
chromatin modification GO:0016568 187 0.024
myeloid leukocyte differentiation GO:0002573 119 0.023
defense response to bacterium GO:0042742 119 0.023
cellular macromolecule catabolic process GO:0044265 206 0.023
regulation of response to wounding GO:1903034 189 0.023
wnt signaling pathway GO:0016055 188 0.023
interspecies interaction between organisms GO:0044419 83 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
dna recombination GO:0006310 92 0.023
connective tissue development GO:0061448 179 0.023
mapk cascade GO:0000165 281 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
cell type specific apoptotic process GO:0097285 268 0.023
leukocyte proliferation GO:0070661 172 0.022
ion transmembrane transport GO:0034220 361 0.022
organophosphate catabolic process GO:0046434 232 0.022
negative regulation of cell cycle GO:0045786 123 0.022
negative regulation of growth GO:0045926 99 0.022
female gamete generation GO:0007292 74 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.022
cellular response to growth factor stimulus GO:0071363 197 0.022
regulation of intracellular protein transport GO:0033157 82 0.022
gliogenesis GO:0042063 141 0.022
microtubule cytoskeleton organization GO:0000226 157 0.022
respiratory system development GO:0060541 190 0.022
cellular response to external stimulus GO:0071496 88 0.021
negative regulation of protein modification process GO:0031400 163 0.021
mitotic cell cycle process GO:1903047 159 0.021
release of cytochrome c from mitochondria GO:0001836 23 0.021
actin filament organization GO:0007015 113 0.021
meiotic nuclear division GO:0007126 115 0.020
spermatid development GO:0007286 108 0.020
glycoprotein metabolic process GO:0009100 116 0.020
glycosyl compound catabolic process GO:1901658 206 0.020
extracellular matrix organization GO:0030198 147 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
multicellular organismal homeostasis GO:0048871 164 0.020
gtp catabolic process GO:0006184 143 0.020
g protein coupled receptor signaling pathway GO:0007186 243 0.020
gland development GO:0048732 330 0.020
leukocyte apoptotic process GO:0071887 71 0.020
regulation of t cell activation GO:0050863 170 0.020
ossification GO:0001503 216 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.020
cytokine mediated signaling pathway GO:0019221 115 0.020
endocytosis GO:0006897 168 0.020
extrinsic apoptotic signaling pathway GO:0097191 126 0.020
regulation of map kinase activity GO:0043405 120 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
tissue homeostasis GO:0001894 115 0.019
regulation of response to dna damage stimulus GO:2001020 34 0.019
single organism cell adhesion GO:0098602 156 0.019
morphogenesis of embryonic epithelium GO:0016331 159 0.019
response to ionizing radiation GO:0010212 42 0.019
positive regulation of protein kinase activity GO:0045860 144 0.019
skin development GO:0043588 220 0.019
regulation of cell cycle process GO:0010564 160 0.019
carboxylic acid transport GO:0046942 100 0.019
nitrogen compound transport GO:0071705 271 0.019
gonad development GO:0008406 141 0.019
regulation of leukocyte proliferation GO:0070663 121 0.019
muscle cell differentiation GO:0042692 261 0.018
negative regulation of interleukin 5 production GO:0032714 4 0.018
alpha beta t cell activation GO:0046631 91 0.018
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.018
protein oligomerization GO:0051259 67 0.018
g1 s transition of mitotic cell cycle GO:0000082 57 0.018
intracellular protein transport GO:0006886 204 0.018
spermatid differentiation GO:0048515 115 0.018
cation homeostasis GO:0055080 212 0.018
neuron death GO:0070997 154 0.018
response to peptide GO:1901652 136 0.018
guanosine containing compound catabolic process GO:1901069 144 0.018
positive regulation of leukocyte differentiation GO:1902107 86 0.018
morphogenesis of a branching structure GO:0001763 203 0.018
engulfment of apoptotic cell GO:0043652 3 0.018
response to growth factor GO:0070848 198 0.018
microtubule based process GO:0007017 236 0.018
divalent inorganic cation transport GO:0072511 178 0.018
peptidyl tyrosine modification GO:0018212 145 0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.018
double strand break repair GO:0006302 48 0.018
rhodopsin mediated signaling pathway GO:0016056 4 0.018
regulation of feeding behavior GO:0060259 3 0.018
regulation of nucleoside metabolic process GO:0009118 130 0.018
positive regulation of smooth muscle cell migration GO:0014911 4 0.018
maintenance of location GO:0051235 89 0.017
regulation of purine nucleotide catabolic process GO:0033121 122 0.017
development of primary sexual characteristics GO:0045137 143 0.017
forebrain development GO:0030900 302 0.017
locomotory behavior GO:0007626 195 0.017
nucleoside phosphate biosynthetic process GO:1901293 79 0.017
regulation of secretion by cell GO:1903530 249 0.017
extracellular structure organization GO:0043062 148 0.017
skeletal muscle organ development GO:0060538 163 0.017
negative regulation of leukocyte differentiation GO:1902106 51 0.017
regulation of cysteine type endopeptidase activity GO:2000116 65 0.017
protein polymerization GO:0051258 57 0.017
cellular response to acid chemical GO:0071229 68 0.017
meiosis i GO:0007127 60 0.017
epithelial cell proliferation GO:0050673 174 0.017
muscle tissue development GO:0060537 308 0.017
regulation of ion transport GO:0043269 215 0.017
protein autophosphorylation GO:0046777 61 0.016
positive regulation of t cell activation GO:0050870 101 0.016
leukocyte homeostasis GO:0001776 79 0.016
negative regulation of mitotic cell cycle GO:0045930 58 0.016
regulation of protein maturation GO:1903317 96 0.016
negative regulation of lymphocyte activation GO:0051250 91 0.016
regulation of lamellipodium assembly GO:0010591 3 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
leukocyte migration GO:0050900 124 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.016
apoptotic mitochondrial changes GO:0008637 48 0.016
cellular ion homeostasis GO:0006873 165 0.016
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.016
negative regulation of dna replication GO:0008156 4 0.016
regulation of cell cycle phase transition GO:1901987 77 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
retina development in camera type eye GO:0060041 119 0.016
mitotic cytokinesis GO:0000281 4 0.016
amide transport GO:0042886 138 0.016
protein localization to organelle GO:0033365 185 0.016
epithelial cell development GO:0002064 159 0.016
positive regulation of organelle organization GO:0010638 128 0.015
leukocyte chemotaxis GO:0030595 69 0.015
regulation of cell adhesion GO:0030155 154 0.015
oxidation reduction process GO:0055114 342 0.015
lung development GO:0030324 164 0.015
ensheathment of neurons GO:0007272 76 0.015
digestive tract development GO:0048565 190 0.015
negative regulation of protein transport GO:0051224 46 0.015
single organismal cell cell adhesion GO:0016337 131 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
protein ubiquitination GO:0016567 171 0.015
negative regulation of molecular function GO:0044092 258 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
alpha beta t cell differentiation GO:0046632 69 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
response to oxygen levels GO:0070482 62 0.015
peptidyl tyrosine phosphorylation GO:0018108 143 0.015
regulation of gtp catabolic process GO:0033124 113 0.015
striated muscle tissue development GO:0014706 293 0.015
regulation of protein processing GO:0070613 96 0.015
positive regulation of innate immune response GO:0045089 80 0.015
regulation of organ morphogenesis GO:2000027 144 0.015
regulation of t cell differentiation GO:0045580 83 0.015
antibacterial peptide biosynthetic process GO:0002780 2 0.015
regulation of actin filament based process GO:0032970 99 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
positive regulation of peptidase activity GO:0010952 49 0.015
myeloid leukocyte migration GO:0097529 57 0.015
regulation of cell activation GO:0050865 289 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
sequestering of calcium ion GO:0051208 18 0.015
dna integrity checkpoint GO:0031570 28 0.015
stem cell differentiation GO:0048863 268 0.015
signal transduction involved in dna integrity checkpoint GO:0072401 3 0.015
protein targeting GO:0006605 143 0.015
regulation of peptidase activity GO:0052547 96 0.015
response to peptide hormone GO:0043434 127 0.015
membrane lipid metabolic process GO:0006643 53 0.014
organic acid transport GO:0015849 101 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
cell division GO:0051301 120 0.014
cell growth GO:0016049 130 0.014
epidermis development GO:0008544 187 0.014
response to nutrient levels GO:0031667 109 0.014
adaptive immune response GO:0002250 155 0.014
stem cell development GO:0048864 219 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
regulation of cytokine production GO:0001817 266 0.014
regulation of neuron apoptotic process GO:0043523 122 0.014
regulation of protein transport GO:0051223 163 0.014
regulation of endopeptidase activity GO:0052548 89 0.014
renal system development GO:0072001 225 0.014
cartilage development GO:0051216 140 0.014
positive regulation of response to wounding GO:1903036 66 0.014
regulation of rho protein signal transduction GO:0035023 71 0.014
regulation of protein binding GO:0043393 60 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.014
glucose homeostasis GO:0042593 128 0.014
cation transmembrane transport GO:0098655 266 0.014
natural killer cell activation GO:0030101 44 0.014
neural tube development GO:0021915 160 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
mitochondrion organization GO:0007005 134 0.014
axon ensheathment GO:0008366 76 0.014
antibacterial peptide production GO:0002778 2 0.014
cellular lipid metabolic process GO:0044255 323 0.014
blood vessel morphogenesis GO:0048514 285 0.014
regulation of anatomical structure size GO:0090066 178 0.014
regulation of acute inflammatory response GO:0002673 27 0.014
methylation GO:0032259 134 0.014
response to transforming growth factor beta GO:0071559 88 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.013
detection of stimulus GO:0051606 84 0.013
striated muscle cell development GO:0055002 125 0.013
regulation of actin cytoskeleton organization GO:0032956 84 0.013
lymphocyte apoptotic process GO:0070227 54 0.013
glial cell differentiation GO:0010001 131 0.013
regulation of synaptic plasticity GO:0048167 87 0.013
positive regulation of gtpase activity GO:0043547 85 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.013
rhythmic process GO:0048511 174 0.013
skeletal system morphogenesis GO:0048705 203 0.013
activation of mapk activity involved in innate immune response GO:0035419 2 0.013
plasma membrane organization GO:0007009 90 0.013
nephron development GO:0072006 109 0.013
response to drug GO:0042493 75 0.013
i kappab kinase nf kappab signaling GO:0007249 85 0.013
negative regulation of phagocytosis GO:0050765 4 0.013
central nervous system neuron differentiation GO:0021953 162 0.013
response to reactive oxygen species GO:0000302 56 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.013
macromolecular complex disassembly GO:0032984 43 0.013
regulation of defense response to bacterium GO:1900424 3 0.013
sulfur compound metabolic process GO:0006790 100 0.013
regulation of stress activated mapk cascade GO:0032872 69 0.013
regulation of transmembrane transport GO:0034762 128 0.012
urogenital system development GO:0001655 261 0.012
myosin filament assembly GO:0031034 2 0.012
peptidyl serine modification GO:0018209 83 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
cell killing GO:0001906 67 0.012
leukocyte mediated immunity GO:0002443 174 0.012
positive regulation of cellular component biogenesis GO:0044089 94 0.012
dna alkylation GO:0006305 43 0.012
cell cycle g1 s phase transition GO:0044843 57 0.012
cytoplasmic transport GO:0016482 234 0.012
dna conformation change GO:0071103 37 0.012
signal transduction in absence of ligand GO:0038034 55 0.012
stress activated protein kinase signaling cascade GO:0031098 81 0.012
norepinephrine secretion GO:0048243 2 0.012
macromolecule methylation GO:0043414 120 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
rac protein signal transduction GO:0016601 13 0.012
regulation of innate immune response GO:0045088 91 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.012
histone modification GO:0016570 159 0.012
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 3 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
negative regulation of t cell activation GO:0050868 65 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
regulation of neuron differentiation GO:0045664 281 0.012
positive regulation of gtp catabolic process GO:0033126 85 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
chemotaxis GO:0006935 247 0.012
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
notch signaling pathway GO:0007219 71 0.012
regulation of body fluid levels GO:0050878 162 0.012
regulation of cell shape GO:0008360 39 0.012
cellular protein complex assembly GO:0043623 116 0.011
autophagy GO:0006914 45 0.011
regulation of protein catabolic process GO:0042176 108 0.011
positive regulation of transferase activity GO:0051347 167 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
regulation of hormone levels GO:0010817 211 0.011
protein secretion GO:0009306 111 0.011
mitotic g1 dna damage checkpoint GO:0031571 4 0.011
progesterone metabolic process GO:0042448 4 0.011
multicellular organismal signaling GO:0035637 91 0.011
sensory perception of umami taste GO:0050917 4 0.011
chromosome segregation GO:0007059 48 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
proteasomal protein catabolic process GO:0010498 98 0.011

Fancc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.071
cancer DOID:162 0 0.071
organ system cancer DOID:0050686 0 0.051
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.047
sensory system disease DOID:0050155 0 0.022
eye disease DOID:5614 0 0.022
retinal disease DOID:5679 0 0.022
eye and adnexa disease DOID:1492 0 0.022
hematopoietic system disease DOID:74 0 0.021
immune system disease DOID:2914 0 0.021
immune system cancer DOID:0060083 0 0.017
hematologic cancer DOID:2531 0 0.017
inherited metabolic disorder DOID:655 0 0.015
disease of metabolism DOID:0014667 0 0.015
central nervous system disease DOID:331 0 0.014
retinal degeneration DOID:8466 0 0.014
brain disease DOID:936 0 0.013
electroclinical syndrome DOID:0050701 0 0.013
epilepsy syndrome DOID:1826 0 0.013