Mus musculus

0 known processes

Fanci

Fanconi anemia, complementation group I

(Aliases: MGC38407,MGC38195)

Fanci biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 107 0.277
meiotic cell cycle process GO:1903046 77 0.223
dna metabolic process GO:0006259 303 0.211
synapsis GO:0007129 34 0.202
meiotic nuclear division GO:0007126 115 0.171
cellular response to dna damage stimulus GO:0006974 207 0.151
organelle fission GO:0048285 170 0.148
nuclear division GO:0000280 158 0.147
meiotic cell cycle GO:0051321 122 0.136
meiosis i GO:0007127 60 0.075
organic cyclic compound catabolic process GO:1901361 295 0.064
cellular amino acid metabolic process GO:0006520 103 0.062
microtubule nucleation GO:0007020 2 0.060
chromosome organization involved in meiosis GO:0070192 39 0.058
organonitrogen compound catabolic process GO:1901565 264 0.050
microtubule based process GO:0007017 236 0.050
male gamete generation GO:0048232 285 0.049
dna recombination GO:0006310 92 0.049
regulation of cellular amino acid metabolic process GO:0006521 5 0.046
macromolecule catabolic process GO:0009057 281 0.046
regulation of cell cycle GO:0051726 281 0.043
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
regulation of cellular ketone metabolic process GO:0010565 66 0.041
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
heterocycle catabolic process GO:0046700 280 0.038
immune effector process GO:0002252 321 0.037
amine metabolic process GO:0009308 45 0.037
leukocyte mediated immunity GO:0002443 174 0.037
mitotic cell cycle GO:0000278 195 0.036
cellular ketone metabolic process GO:0042180 84 0.035
organelle localization GO:0051640 179 0.035
ribonucleoside metabolic process GO:0009119 245 0.034
response to radiation GO:0009314 165 0.034
spermatogenesis GO:0007283 284 0.033
establishment of meiotic spindle orientation GO:0051296 1 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.033
cytokine production GO:0001816 319 0.032
cellular amine metabolic process GO:0044106 44 0.032
adaptive immune response GO:0002250 155 0.031
aromatic compound catabolic process GO:0019439 286 0.031
establishment of spindle localization GO:0051293 19 0.030
t cell activation GO:0042110 289 0.029
regulation of lymphocyte activation GO:0051249 240 0.029
oxidation reduction process GO:0055114 342 0.029
microtubule cytoskeleton organization GO:0000226 157 0.028
mitotic cell cycle process GO:1903047 159 0.028
nucleoside triphosphate catabolic process GO:0009143 205 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.027
macromolecule methylation GO:0043414 120 0.026
regulation of cytokine production GO:0001817 266 0.026
cellular nitrogen compound catabolic process GO:0044270 280 0.026
regulation of protein localization GO:0032880 231 0.026
purine nucleoside catabolic process GO:0006152 205 0.026
cation transport GO:0006812 399 0.024
cellular protein complex assembly GO:0043623 116 0.024
regulation of cell cycle process GO:0010564 160 0.024
maintenance of location GO:0051235 89 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
lymphocyte mediated immunity GO:0002449 139 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.024
nucleoside metabolic process GO:0009116 246 0.023
ribonucleoside catabolic process GO:0042454 206 0.023
regulation of cellular component size GO:0032535 121 0.023
purine nucleotide catabolic process GO:0006195 211 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.023
organophosphate catabolic process GO:0046434 232 0.023
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
glycosyl compound catabolic process GO:1901658 206 0.022
gene silencing GO:0016458 38 0.022
forebrain development GO:0030900 302 0.022
cellular response to biotic stimulus GO:0071216 92 0.022
regulation of organelle organization GO:0033043 289 0.021
establishment or maintenance of cell polarity GO:0007163 86 0.021
protein catabolic process GO:0030163 221 0.021
purine containing compound metabolic process GO:0072521 311 0.021
positive regulation of organelle organization GO:0010638 128 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
peptidyl amino acid modification GO:0018193 336 0.021
glycosyl compound metabolic process GO:1901657 246 0.020
establishment of organelle localization GO:0051656 122 0.020
wnt signaling pathway GO:0016055 188 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
double strand break repair GO:0006302 48 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.019
positive regulation of cell cycle GO:0045787 92 0.019
positive regulation of cell activation GO:0050867 158 0.019
negative regulation of cell cycle phase transition GO:1901988 48 0.019
regulation of neuron differentiation GO:0045664 281 0.019
gonad development GO:0008406 141 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
response to lipopolysaccharide GO:0032496 128 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
leukocyte differentiation GO:0002521 342 0.019
positive regulation of nervous system development GO:0051962 221 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
mapk cascade GO:0000165 281 0.018
b cell activation GO:0042113 161 0.018
purine containing compound catabolic process GO:0072523 213 0.018
regulation of secretion GO:0051046 274 0.018
spindle localization GO:0051653 22 0.018
nucleotide metabolic process GO:0009117 332 0.018
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.018
regulation of mitotic cell cycle GO:0007346 126 0.018
membrane organization GO:0061024 245 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
response to organonitrogen compound GO:0010243 246 0.018
production of molecular mediator of immune response GO:0002440 103 0.017
positive regulation of cell development GO:0010720 237 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
regulation of cell activation GO:0050865 289 0.017
divalent inorganic cation transport GO:0072511 178 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
nucleoside catabolic process GO:0009164 206 0.017
nucleotide catabolic process GO:0009166 217 0.017
regulation of cell cycle g2 m phase transition GO:1902749 10 0.017
lymphocyte proliferation GO:0046651 164 0.017
stem cell development GO:0048864 219 0.017
positive regulation of protein modification process GO:0031401 299 0.017
double strand break repair via homologous recombination GO:0000724 21 0.017
myeloid leukocyte activation GO:0002274 83 0.016
response to molecule of bacterial origin GO:0002237 143 0.016
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.016
leukocyte proliferation GO:0070661 172 0.016
ossification GO:0001503 216 0.016
pallium development GO:0021543 120 0.016
response to cell cycle checkpoint signaling GO:0072396 1 0.016
lymphocyte differentiation GO:0030098 242 0.016
metaphase plate congression GO:0051310 2 0.016
centrosome separation GO:0051299 4 0.016
striated muscle tissue development GO:0014706 293 0.016
cell type specific apoptotic process GO:0097285 268 0.016
leukocyte activation involved in immune response GO:0002366 126 0.016
skeletal system morphogenesis GO:0048705 203 0.016
gland development GO:0048732 330 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
cilium assembly GO:0042384 81 0.015
germ cell development GO:0007281 185 0.015
response to ionizing radiation GO:0010212 42 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
negative regulation of neuron differentiation GO:0045665 101 0.015
homeostasis of number of cells GO:0048872 210 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
positive regulation of immune effector process GO:0002699 107 0.015
stem cell maintenance GO:0019827 130 0.015
atp metabolic process GO:0046034 75 0.015
leukocyte migration GO:0050900 124 0.015
cellular homeostasis GO:0019725 240 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.014
response to gamma radiation GO:0010332 22 0.014
blood vessel morphogenesis GO:0048514 285 0.014
sensory organ morphogenesis GO:0090596 242 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
negative regulation of molecular function GO:0044092 258 0.014
regulation of leukocyte mediated immunity GO:0002703 104 0.014
somatic diversification of immune receptors GO:0002200 53 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
rho protein signal transduction GO:0007266 32 0.014
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.014
regulation of lymphocyte mediated immunity GO:0002706 84 0.014
transmission of nerve impulse GO:0019226 76 0.014
regulation of defense response GO:0031347 233 0.014
female meiosis chromosome segregation GO:0016321 1 0.014
negative regulation of cell development GO:0010721 169 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
regulation of protein catabolic process GO:0042176 108 0.013
negative regulation of nervous system development GO:0051961 156 0.013
regulation of mapk cascade GO:0043408 248 0.013
multicellular organismal signaling GO:0035637 91 0.013
regulation of adaptive immune response GO:0002819 90 0.013
ion transmembrane transport GO:0034220 361 0.013
skeletal system development GO:0001501 356 0.013
generation of precursor metabolites and energy GO:0006091 103 0.013
dna biosynthetic process GO:0071897 22 0.013
cellular chemical homeostasis GO:0055082 215 0.013
regulation of asymmetric cell division GO:0009786 4 0.013
telencephalon development GO:0021537 186 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
microtubule polymerization GO:0046785 12 0.013
compound eye development GO:0048749 1 0.013
lateral inhibition GO:0046331 1 0.013
organelle assembly GO:0070925 177 0.013
regulation of membrane potential GO:0042391 192 0.013
cellular ion homeostasis GO:0006873 165 0.013
cytoplasmic transport GO:0016482 234 0.013
regulation of stem cell proliferation GO:0072091 78 0.013
anatomical structure homeostasis GO:0060249 145 0.013
regulation of secretion by cell GO:1903530 249 0.013
innate immune response GO:0045087 157 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.013
negative regulation of immune system process GO:0002683 209 0.012
regulation of proteolysis GO:0030162 164 0.012
stem cell differentiation GO:0048863 268 0.012
divalent metal ion transport GO:0070838 172 0.012
immunoglobulin mediated immune response GO:0016064 69 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
protein polymerization GO:0051258 57 0.012
regulation of anatomical structure size GO:0090066 178 0.012
camera type eye development GO:0043010 266 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
cellular response to molecule of bacterial origin GO:0071219 83 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
regulation of hydrolase activity GO:0051336 246 0.012
cell adhesion GO:0007155 329 0.012
sensory perception GO:0007600 245 0.012
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
humoral immune response GO:0006959 57 0.012
development of primary male sexual characteristics GO:0046546 88 0.012
transmembrane transport GO:0055085 412 0.012
leukocyte apoptotic process GO:0071887 71 0.012
cellularization GO:0007349 1 0.012
muscle tissue development GO:0060537 308 0.012
positive regulation of cytokine production GO:0001819 174 0.012
cell fate commitment GO:0045165 210 0.012
apoptotic signaling pathway GO:0097190 306 0.012
dephosphorylation GO:0016311 129 0.012
response to dna damage checkpoint signaling GO:0072423 1 0.012
response to light stimulus GO:0009416 135 0.011
regulation of cell migration GO:0030334 219 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.011
regulation of hormone levels GO:0010817 211 0.011
negative regulation of cytoskeleton organization GO:0051494 36 0.011
epithelial tube formation GO:0072175 130 0.011
protein alkylation GO:0008213 81 0.011
actin filament organization GO:0007015 113 0.011
regulation of t cell proliferation GO:0042129 92 0.011
protein processing GO:0016485 163 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
nitrogen compound transport GO:0071705 271 0.011
establishment of spindle orientation GO:0051294 15 0.011
intracellular protein transport GO:0006886 204 0.011
cerebral cortex development GO:0021987 86 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
cellular response to lipid GO:0071396 145 0.011
endomembrane system organization GO:0010256 147 0.011
regulation of microtubule cytoskeleton organization GO:0070507 37 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
recombinational repair GO:0000725 21 0.011
spindle assembly involved in mitosis GO:0090307 4 0.010
cation transmembrane transport GO:0098655 266 0.010
regulation of t cell activation GO:0050863 170 0.010
negative regulation of phosphorus metabolic process GO:0010563 184 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
chromatin organization GO:0006325 206 0.010
histone lysine methylation GO:0034968 50 0.010
regulation of response to wounding GO:1903034 189 0.010
methylation GO:0032259 134 0.010
microtubule polymerization or depolymerization GO:0031109 26 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
positive regulation of cell cycle process GO:0090068 61 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
synaptic transmission GO:0007268 329 0.010
protein ubiquitination GO:0016567 171 0.010
calcium ion transport GO:0006816 159 0.010
male sex differentiation GO:0046661 109 0.010
t cell differentiation GO:0030217 174 0.010
myeloid cell differentiation GO:0030099 233 0.010
cell division GO:0051301 120 0.010
fertilization GO:0009566 127 0.010
connective tissue development GO:0061448 179 0.010

Fanci disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
bone marrow disease DOID:4961 0 0.533
anemia DOID:2355 0 0.533
hematopoietic system disease DOID:74 0 0.533
disease of anatomical entity DOID:7 0 0.533
aplastic anemia DOID:12449 0 0.533
immune system disease DOID:2914 0 0.533
congenital hypoplastic anemia DOID:1342 0 0.533
fanconi s anemia DOID:13636 0 0.183
disease of cellular proliferation DOID:14566 0 0.033
cancer DOID:162 0 0.033
organ system cancer DOID:0050686 0 0.033
nervous system disease DOID:863 0 0.019
sensory system disease DOID:0050155 0 0.013