|
regulation of mast cell activation
|
GO:0033003 |
21 |
1.000
|
|
|
positive regulation of type ii hypersensitivity
|
GO:0002894 |
4 |
1.000
|
|
|
positive regulation of type iii hypersensitivity
|
GO:0001805 |
3 |
1.000
|
|
|
antigen processing and presentation of exogenous peptide antigen via mhc class i
|
GO:0042590 |
6 |
0.999
|
|
|
antigen processing and presentation of peptide antigen via mhc class i
|
GO:0002474 |
9 |
0.998
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.997
|
|
|
fc epsilon receptor signaling pathway
|
GO:0038095 |
3 |
0.997
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
14 |
0.997
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.997
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.997
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.997
|
|
|
regulation of type ii hypersensitivity
|
GO:0002892 |
4 |
0.996
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.995
|
|
|
regulation of type iia hypersensitivity
|
GO:0001796 |
4 |
0.995
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.993
|
|
|
regulation of type i hypersensitivity
|
GO:0001810 |
4 |
0.993
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.992
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.990
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.990
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.989
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.986
|
|
|
antigen processing and presentation of exogenous peptide antigen
|
GO:0002478 |
21 |
0.979
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.979
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.977
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.976
|
|
|
type ii hypersensitivity
|
GO:0002445 |
4 |
0.976
|
|
|
type iii hypersensitivity
|
GO:0001802 |
3 |
0.974
|
|
|
neutrophil activation involved in immune response
|
GO:0002283 |
8 |
0.972
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.970
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.968
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.965
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.965
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.962
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.959
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.959
|
|
|
regulation of type iii hypersensitivity
|
GO:0001803 |
3 |
0.958
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.953
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.951
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.951
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.949
|
|
|
cation transport
|
GO:0006812 |
399 |
0.948
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045425 |
2 |
0.945
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.942
|
|
|
negative regulation of hypersensitivity
|
GO:0002884 |
3 |
0.939
|
|
|
hypersensitivity
|
GO:0002524 |
10 |
0.937
|
|
|
unsaturated fatty acid biosynthetic process
|
GO:0006636 |
15 |
0.932
|
|
|
positive regulation of mast cell activation involved in immune response
|
GO:0033008 |
10 |
0.931
|
|
|
granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0042253 |
2 |
0.931
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.929
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.929
|
Mouse |
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.928
|
|
|
cell cell adhesion via plasma membrane adhesion molecules
|
GO:0098742 |
40 |
0.927
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.927
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.923
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.920
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.918
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.916
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.913
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.912
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.911
|
|
|
leukotriene metabolic process
|
GO:0006691 |
7 |
0.910
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.910
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.909
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.907
|
|
|
positive regulation of type iia hypersensitivity
|
GO:0001798 |
4 |
0.904
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.902
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.902
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.897
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.891
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.890
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.888
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.888
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.887
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.886
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.885
|
|
|
serotonin secretion
|
GO:0001820 |
8 |
0.883
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.882
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.881
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.879
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.877
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.877
|
|
|
positive regulation of acute inflammatory response to antigenic stimulus
|
GO:0002866 |
7 |
0.874
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.872
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.870
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.868
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.866
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.864
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.861
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.846
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.841
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.841
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
27 |
0.840
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.838
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.838
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.834
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.830
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.829
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.828
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.828
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.825
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.821
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.808
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.806
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.806
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.804
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.795
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.785
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.785
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.783
|
|
|
fc receptor signaling pathway
|
GO:0038093 |
6 |
0.779
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.777
|
|
|
monoamine transport
|
GO:0015844 |
33 |
0.776
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
25 |
0.766
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.764
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.762
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.762
|
|
|
metanephric glomerular visceral epithelial cell development
|
GO:0072249 |
2 |
0.762
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.761
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.761
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.754
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.753
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.752
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.751
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.745
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.744
|
|
|
regulation of metanephric mesenchymal cell migration
|
GO:2000589 |
2 |
0.741
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.739
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.733
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.732
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.731
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.731
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.726
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.719
|
|
|
negative regulation of type i hypersensitivity
|
GO:0001811 |
1 |
0.714
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.714
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.714
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.710
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.709
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.708
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.700
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
61 |
0.695
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.694
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.689
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.688
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.688
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.688
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.685
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.676
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
21 |
0.675
|
|
|
t helper 2 cell cytokine production
|
GO:0035745 |
4 |
0.674
|
|
|
humoral immune response mediated by circulating immunoglobulin
|
GO:0002455 |
14 |
0.674
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.671
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.670
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.667
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.666
|
|
|
lipid modification
|
GO:0030258 |
65 |
0.665
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.661
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.661
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.657
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.656
|
|
|
positive regulation of type i hypersensitivity
|
GO:0001812 |
3 |
0.652
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.651
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.646
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.645
|
|
|
positive regulation of mast cell degranulation
|
GO:0043306 |
10 |
0.641
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.640
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.637
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.606
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.599
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.599
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.587
|
|
|
positive regulation of natural killer cell chemotaxis
|
GO:2000503 |
1 |
0.587
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.580
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.577
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.567
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.566
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.566
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor production
|
GO:0032725 |
3 |
0.557
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.555
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.555
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.552
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.541
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.540
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.539
|
|
|
platelet derived growth factor receptor alpha signaling pathway
|
GO:0035790 |
3 |
0.537
|
|
|
cell cell adhesion
|
GO:0098609 |
41 |
0.537
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.537
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.536
|
|
|
neutrophil activation
|
GO:0042119 |
9 |
0.536
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.533
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.532
|
|
|
wound healing
|
GO:0042060 |
157 |
0.532
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.531
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.527
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.523
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.521
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.518
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.504
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.496
|
|
|
interleukin 3 production
|
GO:0032632 |
3 |
0.496
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.492
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.473
|
|
|
antigen processing and presentation of peptide antigen via mhc class ii
|
GO:0002495 |
17 |
0.463
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.461
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.460
|
|
|
antigen processing and presentation of exogenous antigen
|
GO:0019884 |
26 |
0.457
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.453
|
|
|
regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002923 |
10 |
0.447
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.447
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.445
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.442
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.441
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.439
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.439
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.437
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.435
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.433
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.431
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.429
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.428
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.423
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.423
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.422
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.422
|
|
|
coagulation
|
GO:0050817 |
78 |
0.422
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.413
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.410
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.409
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.407
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.405
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.405
|
|
|
acute inflammatory response to antigenic stimulus
|
GO:0002438 |
12 |
0.404
|
|
|
icosanoid metabolic process
|
GO:0006690 |
33 |
0.402
|
|
|
regulation of acute inflammatory response to antigenic stimulus
|
GO:0002864 |
10 |
0.401
|
|
|
regulation of b cell chemotaxis
|
GO:2000537 |
2 |
0.400
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.397
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.394
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.387
|
|
|
granulocyte macrophage colony stimulating factor production
|
GO:0032604 |
3 |
0.387
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.385
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.383
|
|
|
serotonin transport
|
GO:0006837 |
11 |
0.376
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.376
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.375
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.374
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.373
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.369
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.357
|
|
|
negative regulation of t cell mediated immunity
|
GO:0002710 |
9 |
0.353
|
|
|
regulation of hypersensitivity
|
GO:0002883 |
10 |
0.351
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.350
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.348
|
|
|
positive regulation of regulated secretory pathway
|
GO:1903307 |
10 |
0.347
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.345
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.343
|
|
|
positive regulation of mast cell activation
|
GO:0033005 |
12 |
0.339
|
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.337
|
|
|
granulocyte activation
|
GO:0036230 |
10 |
0.337
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.336
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.334
|
|
|
fatty acid derivative metabolic process
|
GO:1901568 |
33 |
0.332
|
|
|
serotonin secretion by platelet
|
GO:0002554 |
3 |
0.329
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.328
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.326
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.319
|
|
|
negative regulation of lymphocyte mediated immunity
|
GO:0002707 |
21 |
0.319
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.318
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.314
|
Mouse |
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.313
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.312
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.311
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.307
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.305
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.302
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.300
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
15 |
0.298
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.297
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.296
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.295
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.294
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.293
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.293
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.291
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.290
|
|
|
unsaturated fatty acid metabolic process
|
GO:0033559 |
31 |
0.290
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.288
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.288
|
|
|
serotonin production involved in inflammatory response
|
GO:0002351 |
4 |
0.287
|
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.285
|
|
|
phagocytosis recognition
|
GO:0006910 |
12 |
0.285
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.283
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.279
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.276
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.276
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.274
|
|
|
positive regulation of tumor necrosis factor biosynthetic process
|
GO:0042535 |
8 |
0.273
|
|
|
positive regulation of leukocyte degranulation
|
GO:0043302 |
10 |
0.273
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.272
|
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.270
|
|
|
leukotriene biosynthetic process
|
GO:0019370 |
5 |
0.268
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.268
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.267
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.266
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.265
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.264
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.261
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.260
|
|
|
icosanoid biosynthetic process
|
GO:0046456 |
15 |
0.258
|
|
|
type iia hypersensitivity
|
GO:0001794 |
4 |
0.254
|
|
|
regulation of interleukin 3 production
|
GO:0032672 |
2 |
0.253
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.253
|
|
|
tumor necrosis factor biosynthetic process
|
GO:0042533 |
10 |
0.251
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.251
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.250
|
|
|
negative regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002924 |
3 |
0.250
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
38 |
0.248
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.245
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.245
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.244
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.243
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.241
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.240
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.240
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.237
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.237
|
|
|
antibody dependent cellular cytotoxicity
|
GO:0001788 |
2 |
0.235
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.234
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.234
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.233
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.228
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.227
|
|
|
negative regulation of t cell mediated cytotoxicity
|
GO:0001915 |
3 |
0.227
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.226
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.224
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.219
|
|
|
purinergic nucleotide receptor signaling pathway
|
GO:0035590 |
3 |
0.218
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.217
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.215
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.213
|
|
|
regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045423 |
2 |
0.213
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.212
|
|
|
positive regulation of dendritic cell dendrite assembly
|
GO:2000549 |
1 |
0.211
|
|
|
metanephric glomerular epithelial cell development
|
GO:0072313 |
2 |
0.207
|
|
|
positive regulation of cd4 positive alpha beta t cell activation
|
GO:2000516 |
16 |
0.206
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.206
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.205
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.205
|
|
|
cd4 positive alpha beta t cell proliferation
|
GO:0035739 |
2 |
0.203
|
|
|
neuron death
|
GO:0070997 |
154 |
0.203
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.203
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.202
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.200
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.198
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.198
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.196
|
|
|
astrocyte cell migration
|
GO:0043615 |
3 |
0.195
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.195
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.192
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.191
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.189
|
|
|
regulation of immunoglobulin production in mucosal tissue
|
GO:2000557 |
1 |
0.187
|
|
|
negative regulation of cell adhesion involved in substrate bound cell migration
|
GO:0006933 |
3 |
0.185
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.184
|
|
|
positive regulation of cytokine production involved in immune response
|
GO:0002720 |
19 |
0.183
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.182
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.177
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.177
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.176
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.174
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.173
|
|
|
regulation of t helper 1 cell cytokine production
|
GO:2000554 |
1 |
0.171
|
|
|
metanephric mesenchymal cell migration
|
GO:0035789 |
2 |
0.170
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.169
|
|
|
positive regulation of glomerulus development
|
GO:0090193 |
5 |
0.167
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.166
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.165
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.162
|
|
|
phospholipid biosynthetic process
|
GO:0008654 |
36 |
0.162
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.162
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.161
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.161
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.159
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.156
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.156
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.155
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.155
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.155
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.153
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.152
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.151
|
|
|
activation of jun kinase activity
|
GO:0007257 |
15 |
0.151
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.150
|
|
|
fc receptor mediated stimulatory signaling pathway
|
GO:0002431 |
4 |
0.149
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.146
|
|
|
regulation of myeloid cell apoptotic process
|
GO:0033032 |
19 |
0.145
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.145
|
|
|
response to drug
|
GO:0042493 |
75 |
0.144
|
|
|
platelet degranulation
|
GO:0002576 |
6 |
0.143
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.141
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.141
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.140
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.137
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.137
|
|
|
cd4 positive cd25 positive alpha beta regulatory t cell differentiation
|
GO:0002361 |
4 |
0.137
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.133
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.133
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
4 |
0.130
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.130
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.130
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.128
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.128
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.127
|
|
|
positive regulation of metanephric glomerulus development
|
GO:0072300 |
4 |
0.127
|
|
|
placenta development
|
GO:0001890 |
140 |
0.126
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.126
|
|
|
leukotriene production involved in inflammatory response
|
GO:0002540 |
2 |
0.125
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.124
|
|
|
fatty acid derivative biosynthetic process
|
GO:1901570 |
15 |
0.124
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.123
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.122
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.122
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.122
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.121
|
|
|
type i hypersensitivity
|
GO:0016068 |
4 |
0.121
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.121
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.120
|
|
|
regulation of retina development in camera type eye
|
GO:1902866 |
3 |
0.120
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.119
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.118
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.116
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.114
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.114
|
|
|
immunoglobulin production in mucosal tissue
|
GO:0002426 |
3 |
0.114
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.113
|
|
|
positive regulation of hypersensitivity
|
GO:0002885 |
7 |
0.111
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.110
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.110
|
|
|
gland development
|
GO:0048732 |
330 |
0.110
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.110
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.109
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
3 |
0.109
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.107
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.106
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.106
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.105
|
|
|
regulation of glucose transport
|
GO:0010827 |
32 |
0.105
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.104
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.103
|
|
|
negative regulation of b cell mediated immunity
|
GO:0002713 |
7 |
0.103
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.102
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.101
|
|
|
positive regulation of thymocyte migration
|
GO:2000412 |
2 |
0.101
|
|
|
metanephric glomerular epithelium development
|
GO:0072244 |
3 |
0.100
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.100
|
|
|
positive regulation of activation of membrane attack complex
|
GO:0001970 |
2 |
0.100
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.100
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.099
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.099
|
|
|
negative regulation of granulocyte differentiation
|
GO:0030853 |
3 |
0.098
|
|
|
dna modification
|
GO:0006304 |
50 |
0.097
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.097
|
|
|
eosinophil migration
|
GO:0072677 |
3 |
0.097
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.096
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.095
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.094
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.094
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.094
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.094
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.094
|
|
|
detection of oxidative stress
|
GO:0070994 |
1 |
0.093
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.093
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.091
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.088
|
|
|
positive regulation of b cell differentiation
|
GO:0045579 |
13 |
0.088
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.086
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.085
|
|
|
myeloid leukocyte cytokine production
|
GO:0061082 |
12 |
0.085
|
|
|
negative regulation of endocytosis
|
GO:0045806 |
12 |
0.084
|
|
|
positive regulation of glucose transport
|
GO:0010828 |
16 |
0.084
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.084
|
|
|
arachidonic acid metabolite production involved in inflammatory response
|
GO:0002538 |
2 |
0.084
|
|