|
|
amine metabolic process
|
GO:0009308 |
45 |
0.717
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.616
|
Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.539
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.538
|
Mouse |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.480
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.468
|
Human Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.453
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.439
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.413
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.401
|
Human Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.398
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.396
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.381
|
Mouse |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.377
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.371
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.369
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.360
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.345
|
Human Mouse Worm |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.344
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.337
|
Human Mouse |
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.335
|
Human Mouse |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.328
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.327
|
Human Mouse |
|
|
developmental maturation
|
GO:0021700 |
193 |
0.326
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.322
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.312
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.312
|
Fly |
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.310
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.299
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.296
|
Human |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.295
|
Human |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.291
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.283
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.271
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.271
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.270
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.265
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.262
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.258
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.257
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.249
|
Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.239
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.239
|
Mouse |
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.235
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.235
|
Human Mouse |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.231
|
Fly |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.221
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.219
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.209
|
Mouse |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.208
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.208
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.207
|
Mouse |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.206
|
Human |
|
|
organelle localization
|
GO:0051640 |
179 |
0.205
|
Human |
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.204
|
Mouse |
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.199
|
Human Mouse |
|
|
cytokine production
|
GO:0001816 |
319 |
0.197
|
Mouse |
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.197
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.195
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.192
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.191
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.189
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.188
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.178
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.177
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.175
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.174
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.172
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.172
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.170
|
Worm |
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.169
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.168
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.165
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.164
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.164
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.164
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.163
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.163
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.162
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.161
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.161
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.161
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.160
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.160
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.157
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.155
|
Human |
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.154
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.152
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.148
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.148
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.147
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.146
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.142
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.142
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.141
|
Mouse |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.141
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.139
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.138
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.135
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.134
|
|
|
|
microglia development
|
GO:0014005 |
2 |
0.133
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.132
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.130
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.125
|
Human |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.123
|
Mouse |
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.122
|
Worm |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.120
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.119
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.118
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.118
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.118
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.117
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.117
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.115
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.114
|
Human |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.110
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.110
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.109
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.108
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.108
|
|
|
|
pancreatic pp cell fate commitment
|
GO:0003329 |
2 |
0.107
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.107
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.106
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.105
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.105
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.105
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.104
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.104
|
Worm |
|
|
organelle assembly
|
GO:0070925 |
177 |
0.103
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.102
|
Human |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.102
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.102
|
Worm |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.101
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.101
|
Human |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.100
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.100
|
|
|
|
positive regulation of regulated secretory pathway
|
GO:1903307 |
10 |
0.100
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.100
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.099
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.099
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.097
|
Human Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.096
|
Mouse |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.095
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.095
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.094
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.091
|
Human |
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.091
|
Mouse |
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
14 |
0.091
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.089
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.088
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.088
|
|
|
|
embryonic olfactory bulb interneuron precursor migration
|
GO:0021831 |
2 |
0.087
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.085
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.085
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.085
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.084
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.084
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.082
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.082
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.080
|
Human |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.080
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.079
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.079
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.079
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.078
|
Human |
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.078
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.076
|
Human |
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.075
|
Human Mouse |
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.075
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.074
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.074
|
|
|
|
toll like receptor 9 signaling pathway
|
GO:0034162 |
6 |
0.074
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.073
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.073
|
Fly |
|
|
nuclear division
|
GO:0000280 |
158 |
0.072
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.072
|
|
|
|
transdifferentiation
|
GO:0060290 |
1 |
0.072
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.072
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.071
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.071
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.070
|
Worm |
|
|
megakaryocyte differentiation
|
GO:0030219 |
26 |
0.070
|
|
|
|
regulation of neural retina development
|
GO:0061074 |
3 |
0.069
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.069
|
Human |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.069
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.069
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.069
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.068
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.068
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.068
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.068
|
Human |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.067
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.067
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.067
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.067
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.067
|
Human Mouse Fly |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.067
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.067
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.067
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.066
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.066
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.066
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.066
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.065
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.065
|
Mouse |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.065
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.065
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.065
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.065
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.064
|
Human |
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.064
|
Mouse Worm |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.063
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.062
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.062
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.062
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.062
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.061
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.061
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.060
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.060
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.060
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.059
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.059
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.059
|
|
|
|
anatomical structure maturation
|
GO:0071695 |
49 |
0.059
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.058
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.058
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.058
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.058
|
|
|
|
negative regulation of oxidative phosphorylation uncoupler activity
|
GO:2000276 |
2 |
0.058
|
|
|
|
neutrophil mediated immunity
|
GO:0002446 |
19 |
0.058
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.057
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.057
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.057
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.057
|
Mouse |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.057
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.057
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.057
|
Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.057
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.056
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.056
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.056
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.056
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.056
|
Human |
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.056
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.056
|
Human |
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.056
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.055
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.055
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.055
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.055
|
Fly |
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.055
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.055
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.054
|
|
|
|
regulation of retina development in camera type eye
|
GO:1902866 |
3 |
0.054
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.054
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.054
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.054
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.053
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.053
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.053
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.053
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.053
|
Human Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.052
|
Human |
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.052
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.052
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.052
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.052
|
|
|
|
regulation of engulfment of apoptotic cell
|
GO:1901074 |
2 |
0.052
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.052
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.052
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.052
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.052
|
Mouse |
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.051
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.051
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.051
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.051
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.051
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.050
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.050
|
|
|
|
positive regulation of exit from mitosis
|
GO:0031536 |
1 |
0.050
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.050
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.050
|
|
|
|
cell proliferation involved in outflow tract morphogenesis
|
GO:0061325 |
4 |
0.050
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.049
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
41 |
0.049
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.049
|
Human |
|
|
bone development
|
GO:0060348 |
120 |
0.049
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.048
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.048
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
55 |
0.048
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.048
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
31 |
0.048
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.048
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.048
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.047
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.047
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.047
|
Mouse Fly |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.047
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.047
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.046
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.046
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.046
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.046
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.046
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.046
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.045
|
Human |
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.045
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.045
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.045
|
|
|
|
positive regulation of mechanoreceptor differentiation
|
GO:0045633 |
1 |
0.045
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.045
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.044
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.044
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.044
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.044
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.044
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.043
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.043
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.043
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.043
|
|
|
|
hair cell differentiation
|
GO:0035315 |
40 |
0.043
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.043
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.043
|
Mouse |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.042
|
Mouse |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.042
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.042
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.042
|
Mouse |
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.042
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.042
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.042
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.042
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.042
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.042
|
|
|
|
protein glycosylation
|
GO:0006486 |
55 |
0.041
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.041
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.041
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.041
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.041
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.041
|
|
|
|
superoxide metabolic process
|
GO:0006801 |
27 |
0.041
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.040
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.040
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.040
|
Human |
|
|
regulation of toll like receptor 9 signaling pathway
|
GO:0034163 |
3 |
0.040
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.040
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.040
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.040
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.040
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.040
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.040
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.039
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.039
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.039
|
Human |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.039
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.038
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation
|
GO:2000721 |
2 |
0.038
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.038
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.038
|
Human Mouse |
|
|
forebrain neuron differentiation
|
GO:0021879 |
52 |
0.038
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.038
|
|
|
|
autonomic nervous system development
|
GO:0048483 |
43 |
0.037
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
21 |
0.037
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.037
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.037
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.037
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
15 |
0.037
|
|
|
|
detection of molecule of bacterial origin
|
GO:0032490 |
2 |
0.037
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.037
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
62 |
0.037
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.037
|
|
|
|
learning
|
GO:0007612 |
98 |
0.037
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.037
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.037
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.037
|
Worm |
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.037
|
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.037
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.037
|
|
|
|
auditory receptor cell fate determination
|
GO:0042668 |
3 |
0.036
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.036
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.036
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.036
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.036
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.036
|
Fly |
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.036
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.036
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.036
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.035
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.035
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.035
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.035
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.035
|
Worm |
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.035
|
|
|
|
positive regulation of keratinocyte proliferation
|
GO:0010838 |
4 |
0.035
|
|
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.035
|
|
|
|
lamellipodium organization
|
GO:0097581 |
29 |
0.034
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.034
|
Human Mouse Worm |
|
|
regulation of system process
|
GO:0044057 |
200 |
0.034
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.034
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.034
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.034
|
Human |
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.034
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.034
|
|
|
|
neuron fate determination
|
GO:0048664 |
9 |
0.034
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.034
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.034
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.033
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.033
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.033
|
|
|
|
intracellular distribution of mitochondria
|
GO:0048312 |
1 |
0.033
|
|
|
|
leukotriene production involved in inflammatory response
|
GO:0002540 |
2 |
0.033
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.033
|
Human |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.033
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.032
|
Human |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.032
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
33 |
0.032
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.032
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.032
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.032
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.032
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.031
|
Mouse |
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.031
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.031
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.031
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.031
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
43 |
0.031
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.031
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.031
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.031
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.031
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.031
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.031
|
|
|
|
face development
|
GO:0060324 |
38 |
0.031
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.031
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.031
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.031
|
|
|
|
tendon cell differentiation
|
GO:0035990 |
4 |
0.030
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.030
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.030
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.030
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.030
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.030
|
Fly |
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.030
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.030
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.030
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.030
|
|
|
|
astrocyte fate commitment
|
GO:0060018 |
4 |
0.030
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
29 |
0.030
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.030
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.030
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.030
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.030
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.029
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
18 |
0.029
|
|
|
|
pancreatic pp cell differentiation
|
GO:0003312 |
2 |
0.029
|
|
|
|
mitral valve development
|
GO:0003174 |
4 |
0.029
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.029
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.029
|
|
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
2 |
0.029
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.029
|
|
|
|
mating
|
GO:0007618 |
27 |
0.029
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.029
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.029
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.029
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.029
|
|
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.029
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.029
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.029
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.028
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.028
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.028
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.028
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.028
|
Human |
|
|
neural tube development
|
GO:0021915 |
160 |
0.028
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.028
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.028
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.028
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.028
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.028
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.028
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.028
|
|
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.027
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.027
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.027
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.027
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.027
|
|
|
|
filopodium assembly
|
GO:0046847 |
19 |
0.027
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.027
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.027
|
|
|
|
negative regulation of type b pancreatic cell apoptotic process
|
GO:2000675 |
3 |
0.027
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.027
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.027
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.027
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.027
|
Mouse |
