Mus musculus

356 known processes

Fgfr3

fibroblast growth factor receptor 3

(Aliases: HBGFR,Mfr3,Fgfr-3,FR3,sam3,Flg-2,CD333)

Fgfr3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
skeletal system development GO:0001501 356 1.000
chondrocyte differentiation GO:0002062 72 1.000
Mouse
skeletal system morphogenesis GO:0048705 203 1.000
chondrocyte development GO:0002063 24 1.000
ossification GO:0001503 216 1.000
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 1.000
embryonic skeletal system development GO:0048706 120 1.000
negative regulation of prostatic bud formation GO:0060686 4 0.999
cartilage development GO:0051216 140 0.999
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.998
regulation of chondrocyte differentiation GO:0032330 33 0.998
endodermal cell fate determination GO:0007493 2 0.998
Fly
osteoblast development GO:0002076 17 0.997
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.997
regionalization GO:0003002 337 0.996
Mouse
organ growth GO:0035265 117 0.996
Mouse
embryonic skeletal joint development GO:0072498 13 0.996
response to fibroblast growth factor GO:0071774 47 0.996
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.996
bone development GO:0060348 120 0.995
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.995
pituitary gland development GO:0021983 38 0.995
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.994
Mouse
appendage development GO:0048736 166 0.994
Mouse
connective tissue development GO:0061448 179 0.994
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.993
appendage morphogenesis GO:0035107 149 0.993
Mouse
regulation of smoothened signaling pathway GO:0008589 58 0.993
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.992
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.992
morphogenesis of an epithelial fold GO:0060571 28 0.992
Mouse
gland development GO:0048732 330 0.992
Mouse Fly
cartilage condensation GO:0001502 18 0.992
morphogenesis of a branching epithelium GO:0061138 193 0.992
Mouse Fly
floor plate morphogenesis GO:0033505 3 0.991
embryonic skeletal system morphogenesis GO:0048704 91 0.991
regulation of organ formation GO:0003156 34 0.991
Mouse
regulation of organ morphogenesis GO:2000027 144 0.990
Mouse
positive regulation of chondrocyte differentiation GO:0032332 13 0.990
morphogenesis of an epithelial bud GO:0060572 18 0.989
Mouse
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.988
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.987
lateral sprouting from an epithelium GO:0060601 13 0.987
Mouse
ureteric bud development GO:0001657 94 0.987
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.986
Mouse Fly
smoothened signaling pathway GO:0007224 105 0.986
morphogenesis of a branching structure GO:0001763 203 0.985
Mouse Fly
diencephalon development GO:0021536 63 0.985
kidney development GO:0001822 213 0.980
Mouse
proteoglycan metabolic process GO:0006029 38 0.980
endochondral bone morphogenesis GO:0060350 50 0.979
prostate gland morphogenetic growth GO:0060737 4 0.978
Mouse
mesenchymal cell proliferation involved in ureter development GO:0072198 4 0.978
prostate gland epithelium morphogenesis GO:0060740 31 0.977
Mouse
axial mesodermal cell fate commitment GO:0048322 1 0.976
regulation of cartilage development GO:0061035 44 0.976
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.975
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.975
limb morphogenesis GO:0035108 149 0.975
Mouse
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.974
bone morphogenesis GO:0060349 78 0.973
cardiac muscle cell proliferation GO:0060038 31 0.973
Mouse
prostate gland morphogenesis GO:0060512 32 0.972
Mouse
positive regulation of cartilage development GO:0061036 18 0.971
cardiac ventricle development GO:0003231 83 0.971
Mouse
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.971
mammary placode formation GO:0060596 4 0.970
angiogenesis GO:0001525 201 0.968
Mouse
branching involved in prostate gland morphogenesis GO:0060442 15 0.968
Mouse
prostate epithelial cord elongation GO:0060523 3 0.968
Mouse
mammary gland morphogenesis GO:0060443 54 0.968
Mouse
limb bud formation GO:0060174 10 0.967
Mouse
negative regulation of cell fate specification GO:0009996 4 0.966
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.966
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.965
limb development GO:0060173 166 0.964
Mouse
metanephric nephron tubule formation GO:0072289 4 0.963
regulation of hippo signaling GO:0035330 1 0.962
replacement ossification GO:0036075 26 0.962
morphogenesis of embryonic epithelium GO:0016331 159 0.961
Mouse
endodermal cell fate specification GO:0001714 4 0.960
prostate gland development GO:0030850 48 0.959
Mouse
lung development GO:0030324 164 0.959
pyramidal neuron migration GO:0021852 1 0.959
forebrain development GO:0030900 302 0.958
regulation of endodermal cell fate specification GO:0042663 2 0.956
regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000163 1 0.955
neural tube closure GO:0001843 90 0.955
embryonic skeletal joint morphogenesis GO:0060272 11 0.954
positive regulation of bmp signaling pathway GO:0030513 23 0.954
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.948
embryonic organ morphogenesis GO:0048562 276 0.948
Mouse
trophectodermal cellular morphogenesis GO:0001831 3 0.948
formation of radial glial scaffolds GO:0021943 4 0.946
mesenchymal cell differentiation GO:0048762 107 0.945
Mouse
negative regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000160 1 0.944
oligodendrocyte development GO:0014003 20 0.944
anterior commissure morphogenesis GO:0021960 6 0.944
forebrain radial glial cell differentiation GO:0021861 4 0.943
positive regulation of phospholipase activity GO:0010518 3 0.943
Human
positive regulation of transcription by glucose GO:0046016 3 0.941
negative regulation of cholesterol transport GO:0032375 4 0.940
respiratory tube development GO:0030323 167 0.938
negative regulation of embryonic development GO:0045992 22 0.935
sensory perception GO:0007600 245 0.935
Mouse
forebrain neuroblast division GO:0021873 9 0.935
Mouse
ascending aorta morphogenesis GO:0035910 3 0.934
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.933
regulation of stem cell differentiation GO:2000736 50 0.931
stem cell development GO:0048864 219 0.930
lung morphogenesis GO:0060425 50 0.930
Mouse
negative regulation of chondrocyte differentiation GO:0032331 13 0.930
renal system development GO:0072001 225 0.929
Mouse Fly
left lung development GO:0060459 4 0.929
blood vessel morphogenesis GO:0048514 285 0.926
Mouse
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.925
prostatic bud formation GO:0060513 10 0.925
stem cell proliferation GO:0072089 117 0.924
Mouse
positive regulation of immature t cell proliferation GO:0033091 4 0.923
positive regulation of dendrite development GO:1900006 21 0.923
negative regulation of stem cell maintenance GO:1902455 4 0.919
roof plate formation GO:0021509 1 0.918
retinal ganglion cell axon guidance GO:0031290 18 0.916
lung lobe morphogenesis GO:0060463 9 0.914
Mouse
mesonephric tubule development GO:0072164 94 0.914
Mouse
branch elongation involved in salivary gland morphogenesis GO:0060667 2 0.913
Mouse
forebrain morphogenesis GO:0048853 17 0.912
epithelial tube morphogenesis GO:0060562 303 0.910
Mouse Fly
sensory organ morphogenesis GO:0090596 242 0.910
male gamete generation GO:0048232 285 0.908
smoothened signaling pathway involved in dorsal ventral neural tube patterning GO:0060831 12 0.907
specification of organ identity GO:0010092 30 0.906
Mouse
glial cell development GO:0021782 54 0.901
renal vesicle induction GO:0072034 3 0.901
positive regulation of hh target transcription factor activity GO:0007228 3 0.900
ventricular cardiac muscle cell differentiation GO:0055012 17 0.900
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.899
respiratory system development GO:0060541 190 0.899
forebrain regionalization GO:0021871 25 0.897
metanephric capsule specification GO:0072267 1 0.896
endodermal digestive tract morphogenesis GO:0061031 4 0.895
Mouse
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.893
endoderm development GO:0007492 45 0.890
Fly
aorta morphogenesis GO:0035909 22 0.889
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation GO:0021938 4 0.888
regulation of cardiac muscle tissue development GO:0055024 31 0.886
Mouse
positive regulation of ossification GO:0045778 47 0.884
negative regulation of smoothened signaling pathway GO:0045879 25 0.883
odontogenesis of dentin containing tooth GO:0042475 66 0.882
sensory perception of sound GO:0007605 97 0.882
Mouse
regulation of steroid biosynthetic process GO:0050810 26 0.880
Mouse
hypophysis morphogenesis GO:0048850 3 0.880
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.879
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.877
muscle cell proliferation GO:0033002 52 0.872
Mouse
organ induction GO:0001759 21 0.872
Mouse
establishment of neuroblast polarity GO:0045200 1 0.870
positive regulation of cell proliferation in bone marrow GO:0071864 2 0.870
Mouse
mesendoderm development GO:0048382 3 0.869
mesenchymal cell differentiation involved in lung development GO:0060915 2 0.868
Mouse
ureter morphogenesis GO:0072197 4 0.866
detection of mechanical stimulus involved in equilibrioception GO:0050973 2 0.862
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.860
regulation of vascular wound healing GO:0061043 2 0.860
fibroblast growth factor receptor signaling pathway involved in mammary gland specification GO:0060595 2 0.858
Mouse
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.856
exocrine system development GO:0035272 45 0.855
Mouse
regulation of endothelial cell proliferation GO:0001936 23 0.854
regulation of cardiac muscle cell proliferation GO:0060043 23 0.852
Mouse
cardiac septum development GO:0003279 59 0.851
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.850
ear development GO:0043583 200 0.850
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.850
regulation of establishment of planar polarity GO:0090175 28 0.848
positive regulation of tendon cell differentiation GO:2001051 1 0.847
primary neural tube formation GO:0014020 95 0.846
cell proliferation in hindbrain GO:0021534 10 0.843
bone mineralization GO:0030282 54 0.843
positive regulation of wnt signaling pathway GO:0030177 45 0.842
positive regulation of stem cell proliferation GO:2000648 59 0.842
Mouse
amine metabolic process GO:0009308 45 0.840
axis elongation GO:0003401 30 0.840
Mouse
transforming growth factor beta receptor signaling pathway involved in primitive streak formation GO:0090010 1 0.839
axis elongation involved in somitogenesis GO:0090245 4 0.838
trachea cartilage morphogenesis GO:0060535 4 0.837
craniofacial suture morphogenesis GO:0097094 10 0.836
Mouse
mammary gland bud morphogenesis GO:0060648 4 0.834
Mouse
forelimb morphogenesis GO:0035136 40 0.831
regulation of ossification GO:0030278 112 0.830
asymmetric neuroblast division GO:0055059 1 0.830
mammary gland bud formation GO:0060615 2 0.830
Mouse
apoptotic process in bone marrow GO:0071839 1 0.829
primary prostatic bud elongation GO:0060516 2 0.828
germ line stem cell division GO:0042078 2 0.827
brain morphogenesis GO:0048854 32 0.824
lateral mesoderm morphogenesis GO:0048369 3 0.819
Mouse
regulation of cardiac muscle tissue growth GO:0055021 26 0.816
Mouse
mammary gland epithelium development GO:0061180 65 0.812
Mouse
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000162 1 0.801
cardiac chamber morphogenesis GO:0003206 93 0.801
Mouse
inner cell mass cellular morphogenesis GO:0001828 1 0.801
developmental maturation GO:0021700 193 0.796
digestive tract development GO:0048565 190 0.795
negative regulation of kinase activity GO:0033673 81 0.794
positive regulation of neuron projection regeneration GO:0070572 2 0.793
regulation of heart growth GO:0060420 31 0.792
Mouse
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.791
regulation of mesodermal cell fate specification GO:0042661 5 0.789
Mouse
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000149 1 0.789
regulation of osteoblast differentiation GO:0045667 67 0.788
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.787
ventricular cardiac muscle cell development GO:0055015 11 0.787
heart morphogenesis GO:0003007 178 0.786
Mouse
embryonic digestive tract morphogenesis GO:0048557 17 0.785
Mouse
ventricular cardiac muscle tissue development GO:0003229 38 0.784
Mouse
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.782
chondroblast differentiation GO:0060591 2 0.782
cardiac muscle tissue development GO:0048738 130 0.781
Mouse
chondrocyte hypertrophy GO:0003415 4 0.779
regulation of hormone levels GO:0010817 211 0.779
female somatic sex determination GO:0019101 1 0.778
negative regulation of epithelial cell proliferation GO:0050680 64 0.778
embryonic epithelial tube formation GO:0001838 130 0.776
cardiac septum morphogenesis GO:0060411 46 0.776
Mouse
regulation of stem cell division GO:2000035 4 0.775
negative regulation of immature t cell proliferation GO:0033087 3 0.773
endodermal cell fate commitment GO:0001711 12 0.772
Fly
neural tube patterning GO:0021532 43 0.772
rostrocaudal neural tube patterning GO:0021903 12 0.771
paraxial mesodermal cell differentiation GO:0048342 2 0.771
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 5 0.770
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 16 0.770
negative regulation of cartilage development GO:0061037 17 0.769
establishment or maintenance of neuroblast polarity GO:0045196 1 0.768
cardiac endothelial cell differentiation GO:0003348 4 0.766
pallium development GO:0021543 120 0.764
positive regulation of smoothened signaling pathway GO:0045880 23 0.764
spinal cord development GO:0021510 81 0.763
regulation of anatomical structure size GO:0090066 178 0.760
Fly
tendon cell differentiation GO:0035990 4 0.759
oocyte axis specification GO:0007309 2 0.757
regulation of neuron projection development GO:0010975 169 0.756
Mouse Fly
tendon formation GO:0035992 4 0.751
male sex differentiation GO:0046661 109 0.750
renal capsule specification GO:0072130 1 0.749
glandular epithelial cell differentiation GO:0002067 38 0.748
Mouse
central nervous system neuron differentiation GO:0021953 162 0.747
Mouse
branch elongation of an epithelium GO:0060602 19 0.743
Mouse
wnt signaling pathway GO:0016055 188 0.742
regulation of fat cell differentiation GO:0045598 81 0.742
regulation of lens epithelial cell proliferation GO:2001109 1 0.740
nephron tubule development GO:0072080 84 0.739
regulation of planar cell polarity pathway involved in neural tube closure GO:2000167 1 0.738
endodermal cell differentiation GO:0035987 14 0.736
Fly
metanephric mesenchyme morphogenesis GO:0072133 4 0.732
cell migration involved in gastrulation GO:0042074 13 0.732
Fly
regulation of mapk cascade GO:0043408 248 0.731
nephric duct formation GO:0072179 4 0.724
trachea formation GO:0060440 3 0.724
growth plate cartilage chondrocyte development GO:0003431 3 0.722
mesenchymal stem cell maintenance involved in nephron morphogenesis GO:0072038 7 0.721
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.717
neural tube development GO:0021915 160 0.715
smoothened signaling pathway involved in ventral spinal cord patterning GO:0021910 7 0.715
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.714
left lung morphogenesis GO:0060460 3 0.712
smad protein signal transduction GO:0060395 21 0.711
detection of external stimulus GO:0009581 61 0.710
cerebellar granule cell precursor proliferation GO:0021930 10 0.708
embryonic digestive tract development GO:0048566 27 0.707
Mouse
kidney epithelium development GO:0072073 121 0.707
Mouse
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000164 1 0.704
embryonic heart tube development GO:0035050 65 0.704
cardiac chamber development GO:0003205 108 0.704
Mouse
regulation of prostatic bud formation GO:0060685 6 0.701
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.699
regulation of myoblast differentiation GO:0045661 29 0.698
negative regulation of cell proliferation GO:0008285 296 0.698
cellular response to cholesterol GO:0071397 2 0.697
bmp signaling pathway GO:0030509 93 0.697
carbon catabolite activation of transcription GO:0045991 4 0.696
vascular wound healing GO:0061042 3 0.689
regulation of mesenchymal cell proliferation GO:0010464 37 0.689
Mouse
regulation of smooth muscle cell differentiation GO:0051150 9 0.687
Mouse
growth plate cartilage development GO:0003417 14 0.686
cellular response to growth factor stimulus GO:0071363 197 0.686
cardiac muscle tissue morphogenesis GO:0055008 44 0.685
Mouse
epiblast cell extraembryonic ectoderm cell signaling involved in anterior posterior axis specification GO:0060802 1 0.679
axon guidance GO:0007411 141 0.678
Worm
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.678
regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000159 1 0.677
odontogenesis GO:0042476 78 0.676
Mouse
endocrine system development GO:0035270 98 0.676
cell proliferation in midbrain GO:0033278 2 0.675
neural nucleus development GO:0048857 22 0.670
globus pallidus development GO:0021759 2 0.664
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis GO:0060527 7 0.663
Mouse
nerve development GO:0021675 67 0.663
cellular response to heparin GO:0071504 1 0.663
closure of optic fissure GO:0061386 2 0.663
regulation of epithelial cell proliferation GO:0050678 141 0.662
mesenchymal cell development GO:0014031 93 0.662
regulation of epithelial cell proliferation involved in lung morphogenesis GO:2000794 5 0.662
Mouse
lacrimal gland development GO:0032808 5 0.660
Mouse
nitrogen compound transport GO:0071705 271 0.659
midbrain hindbrain boundary maturation GO:0021732 1 0.658
regulation of wnt signaling pathway GO:0030111 123 0.656
regulation of mitotic cell cycle GO:0007346 126 0.656
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.655
spermatogenesis GO:0007283 284 0.654
positive regulation of nervous system development GO:0051962 221 0.653
Mouse
regulation of gtp catabolic process GO:0033124 113 0.648
metanephric mesenchymal cell proliferation involved in metanephros development GO:0072136 2 0.646
forebrain ventricular zone progenitor cell division GO:0021869 6 0.644
Mouse
paraxial mesodermal cell fate commitment GO:0048343 2 0.644
ras protein signal transduction GO:0007265 77 0.642
regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000161 1 0.642
cerebral cortex neuron differentiation GO:0021895 19 0.641
nephrogenic mesenchyme development GO:0072076 3 0.640
inhibition of neuroepithelial cell differentiation GO:0002085 2 0.638
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.638
bud elongation involved in lung branching GO:0060449 6 0.634
Mouse
regulation of mesenchymal cell proliferation involved in ureter development GO:0072199 3 0.633
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.632
regulation of skeletal muscle fiber differentiation GO:1902809 3 0.630
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.627
nephron epithelium morphogenesis GO:0072088 68 0.627
apoptotic process involved in morphogenesis GO:0060561 25 0.625
negative regulation of apoptotic process involved in morphogenesis GO:1902338 6 0.623
striated muscle cell development GO:0055002 125 0.623
Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.623
axonogenesis GO:0007409 274 0.623
mesenchymal cell proliferation involved in lung development GO:0060916 5 0.620
Mouse
positive regulation of growth GO:0045927 104 0.620
Mouse
striated muscle tissue development GO:0014706 293 0.619
Mouse
negative regulation of canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060829 1 0.617
negative regulation of planar cell polarity pathway involved in neural tube closure GO:2000168 1 0.614
kidney mesenchyme morphogenesis GO:0072131 4 0.609
cochlea morphogenesis GO:0090103 22 0.608
regulation of branching involved in prostate gland morphogenesis GO:0060687 7 0.602
Mouse
mesenchymal cell proliferation GO:0010463 44 0.601
Mouse
neuroepithelial cell differentiation GO:0060563 37 0.601
epidermal growth factor receptor signaling pathway GO:0007173 28 0.600
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.598
maternal placenta development GO:0001893 20 0.595
multicellular organismal homeostasis GO:0048871 164 0.595
mesodermal cell fate determination GO:0007500 1 0.595
Fly
regulation of embryonic development GO:0045995 71 0.595
Mouse
axial mesoderm formation GO:0048320 3 0.595
muscular septum morphogenesis GO:0003150 4 0.593
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.593
nuclear membrane organization GO:0071763 4 0.592
neuron migration GO:0001764 122 0.592
organ maturation GO:0048799 17 0.592
embryonic heart tube morphogenesis GO:0003143 51 0.590
adenohypophysis development GO:0021984 14 0.589
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.587
negative regulation of kidney development GO:0090185 15 0.586
his purkinje system cell differentiation GO:0060932 2 0.585
gliogenesis GO:0042063 141 0.584
mammary gland formation GO:0060592 9 0.584
Mouse
neural plate development GO:0001840 12 0.582
neuron projection guidance GO:0097485 141 0.578
Worm
peptide secretion GO:0002790 114 0.578
placenta blood vessel development GO:0060674 31 0.577
stem cell differentiation GO:0048863 268 0.577
corticotropin hormone secreting cell differentiation GO:0060128 3 0.577
lung saccule development GO:0060430 7 0.575
negative regulation of endodermal cell differentiation GO:1903225 1 0.571
carbon catabolite repression of transcription GO:0045013 1 0.571
negative regulation of transcription by glucose GO:0045014 1 0.570
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.568
hair follicle development GO:0001942 85 0.568
Mouse
circulatory system process GO:0003013 197 0.566
regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:2000150 1 0.566
inner ear morphogenesis GO:0042472 101 0.566
Mouse
axial mesoderm development GO:0048318 8 0.565
insulin like growth factor receptor signaling pathway GO:0048009 21 0.563
positive regulation of cell activation GO:0050867 158 0.562
urogenital system development GO:0001655 261 0.561
Mouse Fly
neural crest cell migration GO:0001755 32 0.560
epithelial mesenchymal signaling involved in prostate gland development GO:0060738 2 0.560
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.559
lipid localization GO:0010876 126 0.554
multicellular organism growth GO:0035264 161 0.554
Mouse
renal capsule formation GO:0072129 1 0.552
forebrain cell migration GO:0021885 58 0.551
auditory receptor cell fate determination GO:0042668 3 0.551
negative regulation of gastrulation GO:2000542 3 0.549
bone maturation GO:0070977 13 0.548
heart valve development GO:0003170 23 0.546
cell proliferation in external granule layer GO:0021924 10 0.544
growth plate cartilage chondrocyte growth GO:0003430 2 0.540
spinal cord motor neuron differentiation GO:0021522 35 0.540
gastrulation GO:0007369 116 0.537
Mouse Fly
positive regulation of g0 to g1 transition GO:0070318 2 0.536
cerebral cortex development GO:0021987 86 0.535
cell proliferation involved in kidney development GO:0072111 14 0.534
lateral mesodermal cell fate commitment GO:0048372 2 0.533
Mouse
g0 to g1 transition GO:0045023 3 0.530
ossification involved in bone maturation GO:0043931 12 0.527
telencephalon development GO:0021537 186 0.526
canonical wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development GO:0061310 1 0.525
regulation of cellular amino acid metabolic process GO:0006521 5 0.523
innervation GO:0060384 22 0.522
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.521
regulation of glial cell differentiation GO:0045685 41 0.521
cell fate commitment GO:0045165 210 0.520
muscle cell differentiation GO:0042692 261 0.519
Mouse Fly
negative regulation of mesodermal cell fate specification GO:0042662 3 0.519
clara cell differentiation GO:0060486 4 0.519
atrioventricular bundle cell differentiation GO:0003167 1 0.517
hindlimb morphogenesis GO:0035137 42 0.516
regulation of peptide secretion GO:0002791 77 0.516
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.516
lymphocyte differentiation GO:0030098 242 0.515
segmentation GO:0035282 93 0.511
embryonic limb morphogenesis GO:0030326 126 0.511
Mouse
muscle contraction GO:0006936 101 0.510
telencephalon cell migration GO:0022029 55 0.508
developmental growth involved in morphogenesis GO:0060560 138 0.506
Mouse Fly
stem cell fate specification GO:0048866 3 0.506
male genitalia development GO:0030539 20 0.506
cardiac right atrium morphogenesis GO:0003213 3 0.504
response to acid chemical GO:0001101 111 0.502
positive regulation of vascular wound healing GO:0035470 1 0.502
nucleoside metabolic process GO:0009116 246 0.502
middle ear morphogenesis GO:0042474 23 0.500
Mouse
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.494
regulation of cell cycle GO:0051726 281 0.494
face development GO:0060324 38 0.493
orbitofrontal cortex development GO:0021769 2 0.493
Mouse
negative regulation of cardiac muscle tissue development GO:0055026 8 0.489
glomerular mesangial cell development GO:0072144 3 0.489
tooth mineralization GO:0034505 9 0.488
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.488
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.487
telencephalon regionalization GO:0021978 14 0.486
embryonic digit morphogenesis GO:0042733 56 0.486
peptidyl tyrosine modification GO:0018212 145 0.485
pharyngeal system development GO:0060037 17 0.484
cell proliferation involved in metanephros development GO:0072203 9 0.483
detection of stimulus GO:0051606 84 0.483
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.482
mesonephric epithelium development GO:0072163 94 0.480
Mouse
heart formation GO:0060914 16 0.477
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.474
olfactory bulb interneuron development GO:0021891 7 0.472
endothelial cell differentiation GO:0045446 41 0.470
metanephros development GO:0001656 79 0.469
response to cholesterol GO:0070723 4 0.468
axial mesodermal cell fate specification GO:0048327 1 0.468
hindbrain tangential cell migration GO:0021934 2 0.467
prostate gland stromal morphogenesis GO:0060741 2 0.467
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.466
cell differentiation in spinal cord GO:0021515 53 0.465
regulation of cell migration GO:0030334 219 0.465
regulation of bone mineralization GO:0030500 31 0.465
anatomical structure maturation GO:0071695 49 0.462
locus ceruleus development GO:0021703 1 0.462
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.461
guanosine containing compound metabolic process GO:1901068 144 0.461
endochondral bone growth GO:0003416 19 0.460
ear morphogenesis GO:0042471 118 0.458
Mouse
lung induction GO:0060492 3 0.457
muscle cell development GO:0055001 133 0.456
Fly
axial mesodermal cell differentiation GO:0048321 1 0.455
planar dichotomous subdivision of terminal units involved in lung branching morphogenesis GO:0060489 2 0.454
embryonic genitalia morphogenesis GO:0030538 4 0.452
spermatid differentiation GO:0048515 115 0.452
blastocyst formation GO:0001825 33 0.451
cardiac ventricle morphogenesis GO:0003208 50 0.450
Mouse
regulation of lateral mesodermal cell fate specification GO:0048378 2 0.450
Mouse
cardiocyte differentiation GO:0035051 87 0.450
Fly
cell aggregation GO:0098743 18 0.449
guanosine containing compound catabolic process GO:1901069 144 0.449
ovarian follicle development GO:0001541 40 0.449
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.449
midbrain development GO:0030901 35 0.448
negative regulation of platelet derived growth factor receptor beta signaling pathway GO:2000587 2 0.446
metanephric capsule formation GO:0072266 1 0.445
notochord formation GO:0014028 5 0.444
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.443
regulation of endodermal cell differentiation GO:1903224 2 0.440
post anal tail morphogenesis GO:0036342 23 0.439
cellular ketone metabolic process GO:0042180 84 0.439
Mouse
ureteric bud morphogenesis GO:0060675 62 0.439
cardiac muscle tissue growth GO:0055017 37 0.438
Mouse
regulation of metal ion transport GO:0010959 106 0.434

Fgfr3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 1.000
Human
musculoskeletal system disease DOID:17 0 1.000
Human
connective tissue disease DOID:65 0 1.000
Human
bone development disease DOID:0080006 0 1.000
Human
bone disease DOID:0080001 0 1.000
Human
dysostosis DOID:1934 0 0.866