|
|
cytokine production
|
GO:0001816 |
319 |
0.984
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.975
|
Mouse |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.962
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.945
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.944
|
Mouse |
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.943
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.942
|
Mouse |
|
|
serotonin secretion involved in inflammatory response
|
GO:0002442 |
4 |
0.928
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.920
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.918
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.913
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.913
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.907
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.890
|
Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.883
|
Mouse |
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
2 |
0.883
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.873
|
Mouse |
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.868
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.866
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.861
|
Mouse |
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.858
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.851
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.850
|
Mouse |
|
|
immune effector process
|
GO:0002252 |
321 |
0.827
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.818
|
Mouse |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.818
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.816
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.812
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.811
|
|
|
|
serotonin production involved in inflammatory response
|
GO:0002351 |
4 |
0.807
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.807
|
Mouse |
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.797
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.787
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.772
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.761
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.761
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.749
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.742
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.737
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.725
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.723
|
Mouse |
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.717
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.706
|
Mouse |
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.692
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.677
|
Mouse |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.675
|
Mouse |
|
|
neutrophil mediated immunity
|
GO:0002446 |
19 |
0.669
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.667
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.666
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.659
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.655
|
Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.641
|
Mouse |
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.635
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.626
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.608
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.604
|
Mouse |
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.604
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.603
|
Mouse |
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.600
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.598
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.592
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.591
|
Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.591
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.590
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
15 |
0.587
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.572
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.567
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.564
|
Mouse |
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.557
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.548
|
Mouse |
|
|
exocytosis
|
GO:0006887 |
121 |
0.543
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.534
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.532
|
Mouse |
|
|
serotonin transport
|
GO:0006837 |
11 |
0.524
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.523
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.520
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.500
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.499
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.491
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.487
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.484
|
Mouse |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.482
|
Mouse |
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.478
|
|
|
|
keratinocyte migration
|
GO:0051546 |
3 |
0.471
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.470
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.461
|
Mouse |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.461
|
Fly |
|
|
lysosome localization
|
GO:0032418 |
20 |
0.457
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.455
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.454
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.454
|
Mouse |
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.448
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.444
|
Mouse |
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.437
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.435
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.430
|
Mouse |
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.430
|
Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.425
|
Mouse |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.418
|
Human |
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.415
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.413
|
Mouse Fly |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.412
|
Mouse Fly |
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
20 |
0.409
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.401
|
Mouse |
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.394
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.392
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.391
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.390
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.388
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.386
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.384
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.384
|
Mouse Fly |
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.379
|
Human |
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.376
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.373
|
|
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.367
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.365
|
Mouse Fly |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.362
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.361
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.361
|
Mouse |
|
|
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045425 |
2 |
0.360
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
14 |
0.359
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.358
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.354
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.354
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.353
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.353
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.349
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.346
|
|
|
|
positive regulation of mast cell degranulation
|
GO:0043306 |
10 |
0.344
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.343
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
28 |
0.342
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.341
|
Human Mouse Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.339
|
|
|
|
positive regulation of macrophage chemotaxis
|
GO:0010759 |
5 |
0.338
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.336
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.334
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.332
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.325
|
Mouse |
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.322
|
Mouse |
|
|
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation
|
GO:2000721 |
2 |
0.321
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.320
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.319
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.317
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.304
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.302
|
Mouse |
|
|
coagulation
|
GO:0050817 |
78 |
0.299
|
Mouse |
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.296
|
Mouse |
|
|
detection of peptidoglycan
|
GO:0032499 |
1 |
0.293
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.287
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.284
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.282
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.281
|
Mouse |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.278
|
Mouse |
|
|
positive regulation of bone remodeling
|
GO:0046852 |
13 |
0.278
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.277
|
|
|
|
positive regulation of toll like receptor 9 signaling pathway
|
GO:0034165 |
2 |
0.273
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.270
|
Mouse |
|
|
serotonin secretion
|
GO:0001820 |
8 |
0.269
|
|
|
|
monoamine transport
|
GO:0015844 |
33 |
0.267
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.267
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.267
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.267
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.266
|
Mouse Fly |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.265
|
Mouse |
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.263
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.262
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
30 |
0.260
|
Human |
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.256
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.256
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.254
|
Mouse |
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.252
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.252
|
|
|
|
auditory receptor cell fate determination
|
GO:0042668 |
3 |
0.249
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.247
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.243
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.241
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.239
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.235
|
Mouse Fly |
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.234
|
Mouse |
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.233
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.233
|
|
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.232
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.231
|
|
|
|
immunoglobulin transcytosis in epithelial cells
|
GO:0002414 |
2 |
0.230
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.230
|
Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.229
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.226
|
Fly |
|
|
regulation of serotonin secretion
|
GO:0014062 |
3 |
0.225
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.225
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.223
|
Mouse |
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.223
|
Mouse |
|
|
regulation of platelet activation
|
GO:0010543 |
17 |
0.222
|
Mouse |
|
|
innate immune response
|
GO:0045087 |
157 |
0.219
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.219
|
Mouse |
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.219
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.218
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.218
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.216
|
Fly |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.215
|
Mouse |
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.213
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.212
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.211
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.207
|
Mouse |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.207
|
Mouse |
|
|
regulation of osteoblast proliferation
|
GO:0033688 |
15 |
0.206
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.206
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.206
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.204
|
Mouse |
|
|
leukotriene biosynthetic process
|
GO:0019370 |
5 |
0.204
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
13 |
0.203
|
Mouse |
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.201
|
|
|
|
connective tissue replacement involved in inflammatory response wound healing
|
GO:0002248 |
3 |
0.199
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.198
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.198
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.196
|
Human Mouse Fly |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.194
|
Mouse |
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.193
|
Mouse |
|
|
microglia development
|
GO:0014005 |
2 |
0.192
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.191
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.188
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.187
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.185
|
Mouse |
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.184
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.182
|
Fly |
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.181
|
Mouse |
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.180
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.180
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.179
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.178
|
|
|
|
negative regulation of leukocyte degranulation
|
GO:0043301 |
7 |
0.175
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.174
|
Mouse |
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.172
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.172
|
Mouse |
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.172
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.171
|
Mouse |
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.171
|
Mouse |
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.171
|
Mouse |
|
|
pore complex assembly
|
GO:0046931 |
3 |
0.170
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.169
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.166
|
Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.165
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.165
|
|
|
|
cofactor transport
|
GO:0051181 |
4 |
0.165
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.165
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.164
|
Mouse |
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.163
|
|
|
|
positive regulation of regulated secretory pathway
|
GO:1903307 |
10 |
0.162
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.162
|
Mouse |
|
|
forebrain development
|
GO:0030900 |
302 |
0.160
|
Mouse |
|
|
intestinal epithelial structure maintenance
|
GO:0060729 |
4 |
0.157
|
|
|
|
multicellular organismal protein catabolic process
|
GO:0044254 |
1 |
0.157
|
|
|
|
regulation of granulocyte macrophage colony stimulating factor production
|
GO:0032645 |
3 |
0.157
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.156
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.154
|
|
|
|
leukocyte migration involved in inflammatory response
|
GO:0002523 |
7 |
0.153
|
|
|
|
regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling
|
GO:0003027 |
1 |
0.153
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.153
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.151
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.151
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.151
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.150
|
Mouse |
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.149
|
Mouse |
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.149
|
Worm |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.148
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.148
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.147
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.146
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.146
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.144
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.142
|
|
|
|
negative regulation of exocytosis
|
GO:0045920 |
12 |
0.142
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.142
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.141
|
|
|
|
activation of mapk activity involved in innate immune response
|
GO:0035419 |
2 |
0.140
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.140
|
Mouse |
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.140
|
|
|
|
negative regulation of mast cell degranulation
|
GO:0043305 |
4 |
0.139
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.139
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.139
|
Mouse |
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.138
|
Fly |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.137
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.137
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.135
|
Mouse |
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
21 |
0.135
|
Mouse |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.134
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.133
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.132
|
Mouse |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.132
|
|
|
|
negative regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031665 |
3 |
0.132
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.131
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.129
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.129
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.129
|
|
|
|
regulation of bone resorption
|
GO:0045124 |
24 |
0.128
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.128
|
|
|
|
positive regulation of leukocyte degranulation
|
GO:0043302 |
10 |
0.127
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.125
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.125
|
Fly |
|
|
regulation of bone remodeling
|
GO:0046850 |
28 |
0.123
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.122
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.122
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.120
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.120
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.120
|
|
|
|
vascular endothelial growth factor production
|
GO:0010573 |
13 |
0.119
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.118
|
Mouse |
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.118
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.116
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.116
|
Fly |
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.115
|
Mouse |
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.115
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.114
|
Mouse |
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.113
|
|
|
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.113
|
Mouse |
|
|
arachidonic acid metabolite production involved in inflammatory response
|
GO:0002538 |
2 |
0.113
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.113
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.110
|
|
|
|
lipoxin a4 biosynthetic process
|
GO:2001303 |
1 |
0.109
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.109
|
Mouse |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.108
|
|
|
|
response to molecule of fungal origin
|
GO:0002238 |
4 |
0.108
|
|
|
|
leukotriene metabolic process
|
GO:0006691 |
7 |
0.108
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.107
|
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.107
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.107
|
Mouse |
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
17 |
0.106
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.106
|
Mouse |
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.106
|
Worm |
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.106
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.105
|
Fly |
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.104
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.104
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.103
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.102
|
Worm |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.102
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.102
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.102
|
Fly |
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.101
|
Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.101
|
Worm |
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.101
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.101
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.100
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.100
|
Mouse |
|
|
skin development
|
GO:0043588 |
220 |
0.100
|
|
|
|
membrane lipid biosynthetic process
|
GO:0046467 |
32 |
0.099
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
11 |
0.099
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.099
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.099
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.098
|
|
|
|
granulocyte macrophage colony stimulating factor production
|
GO:0032604 |
3 |
0.098
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.097
|
Fly |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.097
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.097
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.096
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.096
|
Mouse Fly |
|
|
cell division
|
GO:0051301 |
120 |
0.095
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.095
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.095
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.094
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.094
|
Mouse |
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.094
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.093
|
Mouse |
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
15 |
0.091
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.091
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.090
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.089
|
Mouse |
|
|
positive regulation of bone resorption
|
GO:0045780 |
13 |
0.089
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.089
|
Mouse |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.089
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.089
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.089
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.089
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.088
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.088
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.088
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.087
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.087
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.086
|
|
|
|
macrophage chemotaxis
|
GO:0048246 |
14 |
0.086
|
|
|
|
serotonin secretion by mast cell
|
GO:0002552 |
1 |
0.085
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.085
|
|
|
|
leukocyte aggregation
|
GO:0070486 |
1 |
0.085
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.085
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.084
|
Mouse |
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.084
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.084
|
|
|
|
platelet degranulation
|
GO:0002576 |
6 |
0.083
|
Mouse |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.083
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.082
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.082
|
Fly |
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.082
|
Mouse |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.082
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.081
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.081
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.081
|
Worm |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.081
|
Mouse |
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.081
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.080
|
|
|
|
positive regulation of tissue remodeling
|
GO:0034105 |
19 |
0.080
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.080
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.080
|
Mouse |
|
|
negative regulation of mast cell activation involved in immune response
|
GO:0033007 |
5 |
0.080
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.080
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.079
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.079
|
Mouse |
|
|
regulation of tissue remodeling
|
GO:0034103 |
38 |
0.079
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.078
|
|
|
|
serotonin secretion by platelet
|
GO:0002554 |
3 |
0.078
|
|
|
|
leukotriene production involved in inflammatory response
|
GO:0002540 |
2 |
0.078
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.078
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.078
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.077
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
28 |
0.077
|
Mouse |
|
|
regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045423 |
2 |
0.077
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.076
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.076
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.075
|
|
|
|
positive regulation of tumor necrosis factor biosynthetic process
|
GO:0042535 |
8 |
0.075
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.075
|
Mouse |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.075
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.075
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.075
|
|
|
|
regulation of vascular endothelial growth factor production
|
GO:0010574 |
13 |
0.075
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.074
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.074
|
Mouse |
|
|
mitral valve morphogenesis
|
GO:0003183 |
4 |
0.073
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.073
|
|
|
|
learning
|
GO:0007612 |
98 |
0.073
|
Fly |
|
|
fatty acid derivative biosynthetic process
|
GO:1901570 |
15 |
0.073
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.073
|
Mouse |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.073
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.072
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.072
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.072
|
Mouse Fly |
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.071
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.071
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.071
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.071
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.070
|
Mouse Fly |
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.070
|
Mouse |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.070
|
|
|
|
fatty acid transport
|
GO:0015908 |
28 |
0.070
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.070
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.070
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.069
|
Mouse Worm |
|
|
regulation of toll like receptor 9 signaling pathway
|
GO:0034163 |
3 |
0.069
|
|
|
|
multicellular organismal macromolecule catabolic process
|
GO:0044266 |
1 |
0.069
|
|
|
|
negative regulation of t helper 1 cell differentiation
|
GO:0045626 |
3 |
0.069
|
|
|
|
g protein coupled acetylcholine receptor signaling pathway
|
GO:0007213 |
4 |
0.069
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.069
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.068
|
Mouse |
|
|
renal system development
|
GO:0072001 |
225 |
0.067
|
|
|
|
regulation of coagulation
|
GO:0050818 |
31 |
0.067
|
Mouse |
|
|
neuron migration
|
GO:0001764 |
122 |
0.067
|
Mouse |
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.067
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.067
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.067
|
Fly |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.067
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.066
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.066
|
Mouse |
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
32 |
0.065
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.065
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.065
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.064
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.064
|
Mouse |
|
|
membrane protein proteolysis
|
GO:0033619 |
10 |
0.064
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.064
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.063
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.063
|
Mouse |
|
|
heart contraction
|
GO:0060047 |
93 |
0.063
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.063
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.063
|
Mouse |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.063
|
|
|
|
cellular response to peptidoglycan
|
GO:0071224 |
4 |
0.063
|
|
|
|
positive regulation of membrane protein ectodomain proteolysis
|
GO:0051044 |
3 |
0.062
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.062
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.062
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.062
|
Mouse |
|
|
synapse organization
|
GO:0050808 |
125 |
0.062
|
Fly |
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.062
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.062
|
Mouse |
|
|
tumor necrosis factor biosynthetic process
|
GO:0042533 |
10 |
0.061
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.061
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.061
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.060
|
|
|
|
face morphogenesis
|
GO:0060325 |
29 |
0.060
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.060
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.060
|
|
|
|
neutrophil differentiation
|
GO:0030223 |
3 |
0.060
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.060
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.060
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.060
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.059
|
|
|
|
regulation of icosanoid secretion
|
GO:0032303 |
8 |
0.059
|
|
