|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
1.000
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.999
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.999
|
|
|
|
isotype switching to ige isotypes
|
GO:0048289 |
7 |
0.999
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.998
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.998
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.998
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.998
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.997
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.997
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.995
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.995
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.995
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.993
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.993
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.992
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.992
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.992
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.992
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.992
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.991
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.991
|
|
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.991
|
|
|
|
t cell homeostasis
|
GO:0043029 |
35 |
0.990
|
|
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.988
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
22 |
0.988
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.987
|
|
|
|
t helper 1 cell lineage commitment
|
GO:0002296 |
2 |
0.986
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.986
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.986
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.986
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.983
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.983
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.982
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.981
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
34 |
0.981
|
|
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.980
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.979
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.977
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.975
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.973
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.973
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.973
|
|
|
|
natural killer cell proliferation
|
GO:0001787 |
3 |
0.972
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
19 |
0.971
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.967
|
Mouse |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.967
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.967
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.966
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.966
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.964
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.960
|
|
|
|
mucosal associated lymphoid tissue development
|
GO:0048537 |
12 |
0.960
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.958
|
|
|
|
positive regulation of notch signaling pathway
|
GO:0045747 |
18 |
0.958
|
|
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
4 |
0.957
|
|
|
|
interleukin 2 biosynthetic process
|
GO:0042094 |
15 |
0.955
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.953
|
|
|
|
positive regulation of isotype switching to ige isotypes
|
GO:0048295 |
4 |
0.949
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:0097296 |
2 |
0.949
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.947
|
|
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
11 |
0.946
|
|
|
|
progesterone metabolic process
|
GO:0042448 |
4 |
0.945
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.942
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.942
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.938
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.936
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.936
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.931
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.930
|
|
|
|
response to interleukin 15
|
GO:0070672 |
3 |
0.927
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.927
|
|
|
|
alpha beta t cell lineage commitment
|
GO:0002363 |
7 |
0.926
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.925
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.924
|
Mouse |
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.921
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.917
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.912
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.912
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.908
|
|
|
|
positive regulation of b cell differentiation
|
GO:0045579 |
13 |
0.901
|
|
|
|
isotype switching to igg isotypes
|
GO:0048291 |
10 |
0.901
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.899
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.898
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.893
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.884
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.877
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.876
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.872
|
|
|
|
t cell lineage commitment
|
GO:0002360 |
13 |
0.867
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.864
|
|
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.843
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.841
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.840
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.837
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.835
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.831
|
|
|
|
positive regulation of natural killer cell proliferation
|
GO:0032819 |
2 |
0.824
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.821
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.814
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.813
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.811
|
|
|
|
negative regulation of type 2 immune response
|
GO:0002829 |
8 |
0.805
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.803
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.802
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.795
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.793
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
15 |
0.792
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.790
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.789
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.786
|
|
|
|
regulation of natural killer cell proliferation
|
GO:0032817 |
2 |
0.781
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.773
|
|
|
|
peyer s patch development
|
GO:0048541 |
12 |
0.771
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.764
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.759
|
|
|
|
cellular response to interleukin 4
|
GO:0071353 |
21 |
0.757
|
|
|
|
regulation of mast cell differentiation
|
GO:0060375 |
3 |
0.754
|
|
|
|
positive regulation of activated t cell proliferation
|
GO:0042104 |
8 |
0.753
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.752
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.737
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.737
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.726
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.725
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.719
|
|
|
|
cellular response to x ray
|
GO:0071481 |
2 |
0.718
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.708
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.706
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.705
|
|
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
7 |
0.704
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.698
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.698
|
|
|
|
positive regulation of dna recombination
|
GO:0045911 |
17 |
0.696
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
28 |
0.695
|
Mouse |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.695
|
|
|
|
gamma delta t cell differentiation
|
GO:0042492 |
11 |
0.694
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.683
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.677
|
|
|
|
natural killer cell differentiation
|
GO:0001779 |
21 |
0.675
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.672
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
3 |
0.671
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.670
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.664
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.661
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.657
|
|
|
|
cd4 positive cd25 positive alpha beta regulatory t cell differentiation
|
GO:0002361 |
4 |
0.649
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.640
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.637
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.635
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.634
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.629
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.623
|
|
|
|
neutrophil differentiation
|
GO:0030223 |
3 |
0.620
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.617
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.616
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.613
|
|
|
|
negative regulation of glycolytic process
|
GO:0045820 |
4 |
0.610
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.610
|
|
|
|
negative regulation of erythrocyte differentiation
|
GO:0045647 |
5 |
0.602
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.596
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.581
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.579
|
Mouse |
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
11 |
0.576
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.574
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.571
|
|
|
|
creatinine metabolic process
|
GO:0046449 |
3 |
0.571
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.567
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.566
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.565
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.563
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.562
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.555
|
|
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.555
|
|
|
|
negative regulation of t helper 1 cell differentiation
|
GO:0045626 |
3 |
0.550
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.540
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.539
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
2 |
0.538
|
|
|
|
regulation of myeloid cell apoptotic process
|
GO:0033032 |
19 |
0.529
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.528
|
Mouse |
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
26 |
0.525
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.525
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.524
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.519
|
|
|
|
cell cell recognition
|
GO:0009988 |
44 |
0.517
|
|
|
|
citrate metabolic process
|
GO:0006101 |
3 |
0.512
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.506
|
|
|
|
myeloid cell apoptotic process
|
GO:0033028 |
22 |
0.503
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.501
|
|
|
|
prolactin signaling pathway
|
GO:0038161 |
5 |
0.498
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.496
|
|
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.496
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.495
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
2 |
0.495
|
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
4 |
0.493
|
|
|
|
positive regulation of cardiac muscle cell apoptotic process
|
GO:0010666 |
3 |
0.489
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.488
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.488
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.486
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.484
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.484
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.480
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.473
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.471
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.468
|
|
|
|
development of secondary male sexual characteristics
|
GO:0046544 |
3 |
0.465
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.464
|
|
|
|
isoleucine metabolic process
|
GO:0006549 |
4 |
0.458
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.458
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.456
|
|
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.452
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.446
|
|
|
|
regulation of isotype switching to ige isotypes
|
GO:0048293 |
7 |
0.441
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.439
|
|
|
|
activation induced cell death of t cells
|
GO:0006924 |
10 |
0.437
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.435
|
|
|
|
neuroblast fate determination
|
GO:0007400 |
1 |
0.434
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.433
|
|
|
|
response to growth hormone
|
GO:0060416 |
7 |
0.433
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.431
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.429
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.429
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.427
|
|
|
|
regulation of gamma delta t cell activation
|
GO:0046643 |
9 |
0.424
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.422
|
|
|
|
macrophage fusion
|
GO:0034238 |
3 |
0.420
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.418
|
|
|
|
response to interleukin 2
|
GO:0070669 |
2 |
0.415
|
|
|
|
gamma delta t cell activation
|
GO:0046629 |
13 |
0.409
|
|
|
|
taurine metabolic process
|
GO:0019530 |
4 |
0.404
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.404
|
|
|
|
lymph node development
|
GO:0048535 |
18 |
0.400
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.394
|
Mouse |
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.393
|
|
|
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.393
|
|
|
|
interleukin 27 mediated signaling pathway
|
GO:0070106 |
1 |
0.392
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.392
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.392
|
|
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.391
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.391
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.391
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.389
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.389
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
6 |
0.389
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.387
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
33 |
0.387
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.381
|
|
|
|
valine metabolic process
|
GO:0006573 |
4 |
0.380
|
|
|
|
response to interleukin 4
|
GO:0070670 |
23 |
0.379
|
|
|
|
regulation of isotype switching to igg isotypes
|
GO:0048302 |
10 |
0.376
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.374
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
31 |
0.367
|
|
|
|
allantoin metabolic process
|
GO:0000255 |
3 |
0.363
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.362
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.361
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.361
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.359
|
|
|
|
neutrophil apoptotic process
|
GO:0001781 |
3 |
0.348
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
27 |
0.348
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.344
|
|
|
|
negative regulation of myeloid cell apoptotic process
|
GO:0033033 |
11 |
0.344
|
|
|
|
dicarboxylic acid metabolic process
|
GO:0043648 |
18 |
0.343
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.341
|
|
|
|
positive regulation of mast cell differentiation
|
GO:0060376 |
1 |
0.339
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.338
|
|
|
|
positive regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042511 |
1 |
0.337
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.335
|
Mouse |
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.334
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.333
|
|
|
|
mast cell differentiation
|
GO:0060374 |
5 |
0.331
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.331
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.327
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.327
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.326
|
|
|
|
t helper 1 cell differentiation
|
GO:0045063 |
13 |
0.326
|
|
|
|
creatine metabolic process
|
GO:0006600 |
4 |
0.325
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.319
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.319
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.318
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.316
|
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.315
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.315
|
|
|
|
regulation of regulatory t cell differentiation
|
GO:0045589 |
7 |
0.310
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.309
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.307
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.306
|
|
|
|
negative regulation of regulatory t cell differentiation
|
GO:0045590 |
2 |
0.304
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.302
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.302
|
Mouse |
|
|
mast cell apoptotic process
|
GO:0033024 |
5 |
0.301
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.298
|
|
|
|
negative regulation of exocytosis
|
GO:0045920 |
12 |
0.298
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.294
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.293
|
|
|
|
positive regulation of natural killer cell differentiation
|
GO:0032825 |
7 |
0.293
|
|
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
3 |
0.292
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001241 |
10 |
0.282
|
|
|
|
positive regulation of interleukin 2 biosynthetic process
|
GO:0045086 |
8 |
0.281
|
|
|
|
negative regulation of alpha beta t cell differentiation
|
GO:0046639 |
12 |
0.280
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.270
|
|
|
|
interleukin 11 mediated signaling pathway
|
GO:0038154 |
2 |
0.267
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.266
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.265
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.265
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.264
|
Human |
|
|
regulation of activation of jak2 kinase activity
|
GO:0010534 |
1 |
0.264
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.264
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.263
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.263
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.262
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
13 |
0.260
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.260
|
|
|
|
interleukin 4 mediated signaling pathway
|
GO:0035771 |
2 |
0.258
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.257
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.256
|
|
|
|
positive regulation of glial cell differentiation
|
GO:0045687 |
21 |
0.254
|
|
|
|
negative regulation of syncytium formation by plasma membrane fusion
|
GO:0034242 |
5 |
0.254
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
18 |
0.252
|
|
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
5 |
0.251
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.251
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.250
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.249
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.245
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.244
|
|
|
|
cellular lactam metabolic process
|
GO:0072338 |
3 |
0.240
|
|
|
|
regulation of activated t cell proliferation
|
GO:0046006 |
16 |
0.238
|
|
|
|
regulation of gamma delta t cell differentiation
|
GO:0045586 |
9 |
0.237
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.236
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.231
|
|
|
|
positive regulation of growth hormone receptor signaling pathway
|
GO:0060399 |
3 |
0.229
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
25 |
0.229
|
|
|
|
regulation of macrophage fusion
|
GO:0034239 |
3 |
0.228
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.228
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.228
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.228
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.228
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.227
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.225
|
|
|
|
luteinization
|
GO:0001553 |
8 |
0.224
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.223
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.220
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.216
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.216
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.215
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.212
|
|
|
|
regulation of interleukin 1 beta secretion
|
GO:0050706 |
15 |
0.207
|
|
|
|
spleen development
|
GO:0048536 |
39 |
0.202
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.201
|
|
|
|
negative regulation of t helper cell differentiation
|
GO:0045623 |
9 |
0.200
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.200
|
|
|
|
tricarboxylic acid metabolic process
|
GO:0072350 |
5 |
0.199
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.198
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.197
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.196
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.196
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.195
|
|
|
|
positive regulation of mast cell proliferation
|
GO:0070668 |
3 |
0.195
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.194
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.191
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.185
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.184
|
|
|
|
positive regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043372 |
14 |
0.184
|
|
|
|
spinal cord dorsal ventral patterning
|
GO:0021513 |
23 |
0.183
|
|
|
|
response to estrogen
|
GO:0043627 |
24 |
0.183
|
|
|
|
regulation of interleukin 6 biosynthetic process
|
GO:0045408 |
11 |
0.183
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.181
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
35 |
0.178
|
|
|
|
phospholipid homeostasis
|
GO:0055091 |
6 |
0.178
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.177
|
|
|
|
t helper 17 cell lineage commitment
|
GO:0072540 |
4 |
0.177
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
41 |
0.176
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.176
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.176
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.176
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.175
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.174
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.171
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.170
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.169
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.169
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.168
|
|
|
|
succinate metabolic process
|
GO:0006105 |
4 |
0.167
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.167
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.165
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.164
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.164
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.163
|
|
|
|
response to x ray
|
GO:0010165 |
11 |
0.163
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.163
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.162
|
|
|
|
positive regulation of natural killer cell activation
|
GO:0032816 |
15 |
0.158
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.158
|
|
|
|
regulation of mast cell apoptotic process
|
GO:0033025 |
5 |
0.158
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.157
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.156
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.154
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.153
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.151
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.149
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.147
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.145
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.143
|
|
|
|
immature b cell differentiation
|
GO:0002327 |
10 |
0.143
|
Mouse |
|
|
positive regulation of activation of membrane attack complex
|
GO:0001970 |
2 |
0.142
|
|
|
|
granulocyte activation
|
GO:0036230 |
10 |
0.139
|
|
|
|
lymphocyte costimulation
|
GO:0031294 |
15 |
0.137
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.136
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.136
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.135
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.135
|
|
|
|
male courtship behavior
|
GO:0008049 |
2 |
0.132
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.132
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
20 |
0.132
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.132
|
|
|
|
regulation of neuron migration
|
GO:2001222 |
22 |
0.131
|
|
|
|
regulation of natural killer cell activation
|
GO:0032814 |
22 |
0.130
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
12 |
0.129
|
|
|
|
segment specification
|
GO:0007379 |
15 |
0.129
|
|
|
|
hypersensitivity
|
GO:0002524 |
10 |
0.126
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.125
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.123
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.123
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.121
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.120
|
|
|
|
negative regulation of mast cell apoptotic process
|
GO:0033026 |
4 |
0.119
|
|
|
|
positive regulation of cd4 positive cd25 positive alpha beta regulatory t cell differentiation
|
GO:0032831 |
2 |
0.119
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.118
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.118
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.117
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
39 |
0.116
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.115
|
|
|
|
negative regulation of ripoptosome assembly involved in necroptotic process
|
GO:1902443 |
3 |
0.114
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.113
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
59 |
0.112
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.112
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.111
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
18 |
0.111
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.111
|
|
|
|
negative regulation of necrotic cell death
|
GO:0060547 |
11 |
0.111
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.111
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.110
|
|
|
|
exocrine system development
|
GO:0035272 |
45 |
0.109
|
|
|
|
cellular response to interleukin 15
|
GO:0071350 |
2 |
0.108
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.107
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.106
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.106
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.105
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.104
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.104
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.103
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.103
|
Mouse |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.101
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.101
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.100
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.099
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.099
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.098
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.098
|
|
|
|
branched chain amino acid metabolic process
|
GO:0009081 |
6 |
0.097
|
|
|
|
positive regulation of defense response to virus by host
|
GO:0002230 |
6 |
0.097
|
|
|
|
cellular response to type i interferon
|
GO:0071357 |
10 |
0.097
|
|
|
|
epithelial cell differentiation involved in prostate gland development
|
GO:0060742 |
13 |
0.096
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.096
|
|
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
14 |
0.095
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.094
|
|
|
|
t cell homeostatic proliferation
|
GO:0001777 |
4 |
0.094
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.093
|
|
|
|
positive regulation of gene silencing by mirna
|
GO:2000637 |
1 |
0.093
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.093
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.093
|
Mouse |
|
|
response to hyperoxia
|
GO:0055093 |
2 |
0.093
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.092
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.092
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
18 |
0.092
|
|
|
|
positive regulation of hypersensitivity
|
GO:0002885 |
7 |
0.091
|
|
|
|
positive regulation of translational initiation
|
GO:0045948 |
4 |
0.091
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.091
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.091
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.090
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.090
|
Mouse |
|
|
growth hormone receptor signaling pathway
|
GO:0060396 |
7 |
0.089
|
|
|
|
negative regulation of signal transduction in absence of ligand
|
GO:1901099 |
16 |
0.089
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.089
|
|
|
|
germ line stem cell maintenance
|
GO:0030718 |
6 |
0.088
|
|
|
|
dendritic cell cytokine production
|
GO:0002371 |
3 |
0.088
|
|
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.088
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.087
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.087
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.087
|
|
|
|
positive regulation of interleukin 1 secretion
|
GO:0050716 |
14 |
0.087
|
|
