Mus musculus

57 known processes

Fxr1

fragile X mental retardation gene 1, autosomal homolog

(Aliases: AI851072,1110050J02Rik,9530073J07Rik,Fxr1h,Fxr1p)

Fxr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
translational initiation GO:0006413 24 0.440
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.376
Fly
axoneme assembly GO:0035082 15 0.366
Fly
cilium morphogenesis GO:0060271 102 0.298
Fly
translation GO:0006412 93 0.274
oocyte construction GO:0007308 2 0.234
Fly
male gamete generation GO:0048232 285 0.234
Fly
regulation of insulin receptor signaling pathway GO:0046626 21 0.193
Fly
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.189
Fly
cellularization GO:0007349 1 0.185
Fly
nucleic acid transport GO:0050657 18 0.172
Fly
olfactory learning GO:0008355 2 0.167
Fly
synaptic transmission GO:0007268 329 0.162
Fly
spermatogenesis GO:0007283 284 0.161
Fly
rna localization GO:0006403 23 0.159
Fly
response to peptide hormone GO:0043434 127 0.154
Fly
negative regulation of cellular protein metabolic process GO:0032269 247 0.150
nitrogen compound transport GO:0071705 271 0.147
Fly
organelle assembly GO:0070925 177 0.147
Fly
stem cell differentiation GO:0048863 268 0.147
spermatid differentiation GO:0048515 115 0.146
Fly
microtubule based process GO:0007017 236 0.137
Fly
cellular response to insulin stimulus GO:0032869 78 0.133
Fly
negative regulation of translation GO:0017148 22 0.131
habituation GO:0046959 3 0.131
Fly
germ cell development GO:0007281 185 0.131
Fly
stem cell development GO:0048864 219 0.128
cilium assembly GO:0042384 81 0.128
Fly
negative regulation of translational initiation GO:0045947 4 0.123
Mouse
regulation of translation GO:0006417 71 0.112
cellular component assembly involved in morphogenesis GO:0010927 139 0.112
Fly
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.104
Fly
insulin receptor signaling pathway GO:0008286 49 0.103
Fly
macromolecule catabolic process GO:0009057 281 0.103
heterochromatin organization GO:0070828 4 0.102
Fly
cellular protein catabolic process GO:0044257 155 0.099
posttranscriptional regulation of gene expression GO:0010608 155 0.098
response to organonitrogen compound GO:0010243 246 0.097
Fly
regulation of translational initiation GO:0006446 15 0.097
Mouse
establishment of rna localization GO:0051236 18 0.095
Fly
synapse organization GO:0050808 125 0.094
Fly
cellular response to peptide hormone stimulus GO:0071375 92 0.091
Fly
negative regulation of cellular component organization GO:0051129 194 0.089
Fly
cellular macromolecule catabolic process GO:0044265 206 0.087
detection of stimulus GO:0051606 84 0.085
Fly
chromatin modification GO:0016568 187 0.083
Fly
response to peptide GO:1901652 136 0.083
Fly
regulation of neurotransmitter levels GO:0001505 87 0.081
Fly
nucleoside triphosphate metabolic process GO:0009141 230 0.081
cellular response to organonitrogen compound GO:0071417 145 0.081
Fly
nucleoside triphosphate catabolic process GO:0009143 205 0.079
aromatic compound catabolic process GO:0019439 286 0.076
spermatid development GO:0007286 108 0.075
Fly
cellular response to peptide GO:1901653 92 0.075
Fly
negative regulation of protein metabolic process GO:0051248 282 0.073
purine containing compound metabolic process GO:0072521 311 0.073
nucleoside metabolic process GO:0009116 246 0.073
negative regulation of growth GO:0045926 99 0.072
Fly
nucleoside phosphate catabolic process GO:1901292 222 0.071
regulation of synapse structural plasticity GO:0051823 4 0.066
Fly
cellular response to hormone stimulus GO:0032870 150 0.065
Fly
sensory perception of touch GO:0050975 2 0.065
Fly
heterochromatin assembly GO:0031507 2 0.064
Fly
purine ribonucleotide catabolic process GO:0009154 208 0.064
response to insulin GO:0032868 100 0.064
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.063
dna conformation change GO:0071103 37 0.062
Fly
cellular nitrogen compound catabolic process GO:0044270 280 0.062
male courtship behavior GO:0008049 2 0.062
Fly
locomotory behavior GO:0007626 195 0.061
Fly
protein catabolic process GO:0030163 221 0.061
organic cyclic compound catabolic process GO:1901361 295 0.060
neurotransmitter secretion GO:0007269 62 0.060
Fly
dna metabolic process GO:0006259 303 0.059
Fly
regulation of cell cycle GO:0051726 281 0.058
Fly
negative regulation of neuron differentiation GO:0045665 101 0.058
Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.057
regulation of cellular component biogenesis GO:0044087 181 0.057
Fly
mitotic cell cycle GO:0000278 195 0.055
Fly
purine nucleoside triphosphate metabolic process GO:0009144 226 0.054
heterocycle catabolic process GO:0046700 280 0.052
fertilization GO:0009566 127 0.052
negative regulation of cell development GO:0010721 169 0.052
Fly
glycosyl compound metabolic process GO:1901657 246 0.051
carbohydrate derivative catabolic process GO:1901136 231 0.051
modification dependent macromolecule catabolic process GO:0043632 133 0.050
rna transport GO:0050658 18 0.049
Fly
dendrite development GO:0016358 115 0.049
Fly
negative regulation of neuron projection development GO:0010977 50 0.048
Fly
ribose phosphate metabolic process GO:0019693 291 0.047
morphogenesis of a branching structure GO:0001763 203 0.047
purine ribonucleoside catabolic process GO:0046130 205 0.047
regulation of neuron differentiation GO:0045664 281 0.047
Fly
protein modification by small protein conjugation or removal GO:0070647 207 0.047
ribonucleotide catabolic process GO:0009261 208 0.046
purine ribonucleotide metabolic process GO:0009150 290 0.045
regulation of system process GO:0044057 200 0.045
Fly
negative regulation of dendrite development GO:2000171 9 0.045
Fly
ribonucleotide metabolic process GO:0009259 291 0.045
nucleotide metabolic process GO:0009117 332 0.045
striated muscle tissue development GO:0014706 293 0.044
Zebrafish
cognition GO:0050890 149 0.043
Fly
negative regulation of cell projection organization GO:0031345 56 0.043
Fly
nucleotide catabolic process GO:0009166 217 0.042
cell maturation GO:0048469 127 0.041
Fly
purine ribonucleoside metabolic process GO:0046128 241 0.040
chromatin organization GO:0006325 206 0.040
Fly
regulation of neural precursor cell proliferation GO:2000177 70 0.040
Fly
maintenance of location GO:0051235 89 0.040
regulation of mitotic cell cycle GO:0007346 126 0.039
Fly
proteasomal protein catabolic process GO:0010498 98 0.039
purine nucleoside catabolic process GO:0006152 205 0.039
protein modification by small protein conjugation GO:0032446 187 0.038
negative regulation of nervous system development GO:0051961 156 0.038
Fly
ribonucleoside catabolic process GO:0042454 206 0.038
detection of abiotic stimulus GO:0009582 60 0.038
Fly
atp catabolic process GO:0006200 55 0.037
nucleoside phosphate metabolic process GO:0006753 338 0.037
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.037
developmental maturation GO:0021700 193 0.037
Fly
neural precursor cell proliferation GO:0061351 121 0.037
Fly
organophosphate catabolic process GO:0046434 232 0.036
ribonucleoside triphosphate catabolic process GO:0009203 199 0.036
multi multicellular organism process GO:0044706 109 0.035
Fly
multicellular organism growth GO:0035264 161 0.035
nucleoside catabolic process GO:0009164 206 0.034
learning or memory GO:0007611 148 0.033
Fly
regulation of stem cell proliferation GO:0072091 78 0.033
Fly
purine nucleoside metabolic process GO:0042278 241 0.033
detection of mechanical stimulus involved in sensory perception GO:0050974 23 0.033
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.033
Fly
regulation of kinase activity GO:0043549 249 0.033
purine nucleoside triphosphate catabolic process GO:0009146 203 0.032
rhythmic process GO:0048511 174 0.032
Fly
cell recognition GO:0008037 83 0.032
Fly
chemotaxis GO:0006935 247 0.032
Fly
cellular amine metabolic process GO:0044106 44 0.031
purine nucleoside monophosphate metabolic process GO:0009126 81 0.030
apoptotic signaling pathway GO:0097190 306 0.030
purine nucleotide catabolic process GO:0006195 211 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
regulation of cell cycle phase transition GO:1901987 77 0.030
dna packaging GO:0006323 30 0.030
Fly
muscle tissue development GO:0060537 308 0.029
Zebrafish
nuclear division GO:0000280 158 0.029
axonal fasciculation GO:0007413 15 0.029
Fly
regulation of cellular response to insulin stimulus GO:1900076 30 0.029
Fly
purine containing compound catabolic process GO:0072523 213 0.029
transmembrane transport GO:0055085 412 0.028
regulation of cell projection organization GO:0031344 206 0.028
Fly
regulation of cellular ketone metabolic process GO:0010565 66 0.028
positive regulation of nervous system development GO:0051962 221 0.028
Fly
ribonucleoside triphosphate metabolic process GO:0009199 220 0.028
amine metabolic process GO:0009308 45 0.027
ribonucleoside monophosphate catabolic process GO:0009158 57 0.027
rna interference GO:0016246 2 0.026
ribonucleoside monophosphate metabolic process GO:0009161 80 0.026
cell fate commitment GO:0045165 210 0.026
Fly
purine nucleotide metabolic process GO:0006163 302 0.026
glycosyl compound catabolic process GO:1901658 206 0.026
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
purine nucleoside monophosphate catabolic process GO:0009128 58 0.025
muscle cell differentiation GO:0042692 261 0.025
Zebrafish
nucleoside monophosphate catabolic process GO:0009125 59 0.025
regulation of synapse assembly GO:0051963 29 0.025
Fly
organonitrogen compound catabolic process GO:1901565 264 0.025
cellular protein complex assembly GO:0043623 116 0.025
nucleocytoplasmic transport GO:0006913 139 0.025
cellular ketone metabolic process GO:0042180 84 0.025
intracellular protein transport GO:0006886 204 0.025
cytoplasmic transport GO:0016482 234 0.024
membrane organization GO:0061024 245 0.024
mitotic nuclear division GO:0007067 48 0.024
connective tissue development GO:0061448 179 0.024
peptidyl amino acid modification GO:0018193 336 0.024
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.024
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.024
Fly
chromatin assembly GO:0031497 13 0.024
Fly
protein ubiquitination GO:0016567 171 0.024
organelle localization GO:0051640 179 0.023
detection of external stimulus GO:0009581 61 0.023
Fly
cellular response to dna damage stimulus GO:0006974 207 0.023
associative learning GO:0008306 61 0.023
Fly
detection of mechanical stimulus GO:0050982 27 0.023
Fly
stem cell maintenance GO:0019827 130 0.023
modification dependent protein catabolic process GO:0019941 133 0.022
lipid localization GO:0010876 126 0.022
development of primary sexual characteristics GO:0045137 143 0.022
mitotic cell cycle process GO:1903047 159 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
mitochondrion organization GO:0007005 134 0.022
cell growth GO:0016049 130 0.022
memory GO:0007613 58 0.022
Fly
positive regulation of programmed cell death GO:0043068 218 0.022
regulation of cellular amine metabolic process GO:0033238 20 0.021
neuromuscular synaptic transmission GO:0007274 16 0.021
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
regulation of protein catabolic process GO:0042176 108 0.021
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.021
nucleoside monophosphate metabolic process GO:0009123 85 0.020
learning GO:0007612 98 0.020
Fly
regulation of neurological system process GO:0031644 22 0.020
Fly
oogenesis GO:0048477 56 0.020
Fly
microtubule cytoskeleton organization GO:0000226 157 0.020
Fly
protein maturation GO:0051604 176 0.020
oocyte differentiation GO:0009994 35 0.019
Fly
regulation of organelle organization GO:0033043 289 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
chromatin assembly or disassembly GO:0006333 16 0.019
Fly
cartilage development GO:0051216 140 0.019
regulation of cellular response to stress GO:0080135 159 0.019
synapse assembly GO:0007416 56 0.017
Fly
cation homeostasis GO:0055080 212 0.017
cation transport GO:0006812 399 0.017
regionalization GO:0003002 337 0.017
Zebrafish Fly
meiotic cell cycle GO:0051321 122 0.017
atp metabolic process GO:0046034 75 0.017
cell fate specification GO:0001708 72 0.017
negative regulation of mitotic cell cycle GO:0045930 58 0.017
cellular homeostasis GO:0019725 240 0.017
regulation of protein localization GO:0032880 231 0.017
neural tube development GO:0021915 160 0.017
positive regulation of cell death GO:0010942 224 0.017
regulation of hydrolase activity GO:0051336 246 0.017
neural tube patterning GO:0021532 43 0.017
adult behavior GO:0030534 135 0.016
neuron projection guidance GO:0097485 141 0.016
Fly
negative regulation of protein modification process GO:0031400 163 0.016
positive regulation of stem cell proliferation GO:2000648 59 0.016
Fly
epithelial to mesenchymal transition GO:0001837 47 0.016
detection of stimulus involved in sensory perception GO:0050906 44 0.016
Fly
regulation of intracellular transport GO:0032386 159 0.016
female gamete generation GO:0007292 74 0.016
Fly
protein refolding GO:0042026 1 0.016
stem cell proliferation GO:0072089 117 0.016
Fly
nuclear transport GO:0051169 139 0.016
oocyte development GO:0048599 33 0.015
Fly
regulation of protein maturation GO:1903317 96 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
cation transmembrane transport GO:0098655 266 0.015
regulation of cellular amino acid metabolic process GO:0006521 5 0.015
regulation of transferase activity GO:0051338 263 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
regulation of embryonic development GO:0045995 71 0.015
Fly
meiotic nuclear division GO:0007126 115 0.015
protein processing GO:0016485 163 0.015
adaptive immune response GO:0002250 155 0.015
leukocyte mediated immunity GO:0002443 174 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
establishment of organelle localization GO:0051656 122 0.014
positive regulation of cell cycle GO:0045787 92 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
multi organism reproductive behavior GO:0044705 29 0.014
Fly
negative regulation of protein maturation GO:1903318 79 0.014
t cell activation GO:0042110 289 0.014
regulation of cell migration GO:0030334 219 0.014
cellular amino acid metabolic process GO:0006520 103 0.014
regulation of cell motility GO:2000145 236 0.014
response to light stimulus GO:0009416 135 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
immune effector process GO:0002252 321 0.014
regulation of proteolysis GO:0030162 164 0.013
short term memory GO:0007614 5 0.013
Fly
negative regulation of phosphorylation GO:0042326 166 0.013
axonogenesis GO:0007409 274 0.013
Fly
cell adhesion GO:0007155 329 0.013
oocyte axis specification GO:0007309 2 0.013
Fly
regulation of mitotic cell cycle phase transition GO:1901990 73 0.013
response to inorganic substance GO:0010035 96 0.013
rna processing GO:0006396 105 0.013
cellular chemical homeostasis GO:0055082 215 0.013
inflammatory response GO:0006954 244 0.013
regulation of cellular component size GO:0032535 121 0.013
skeletal system development GO:0001501 356 0.013
mating GO:0007618 27 0.013
Fly
response to growth factor GO:0070848 198 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
regulation of protein transport GO:0051223 163 0.013
histone modification GO:0016570 159 0.012
mapk cascade GO:0000165 281 0.012
rhythmic behavior GO:0007622 15 0.012
Fly
b cell activation GO:0042113 161 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
regulation of cellular protein catabolic process GO:1903362 61 0.012
neural crest formation GO:0014029 2 0.012
regulation of ion transport GO:0043269 215 0.012
organelle fission GO:0048285 170 0.012
forebrain development GO:0030900 302 0.012
protein localization to organelle GO:0033365 185 0.012
neuron migration GO:0001764 122 0.012
single fertilization GO:0007338 82 0.012
myosin filament organization GO:0031033 3 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
carbohydrate homeostasis GO:0033500 128 0.012
myosin filament assembly GO:0031034 2 0.012
ion transmembrane transport GO:0034220 361 0.011
negative regulation of immune system process GO:0002683 209 0.011
mating behavior GO:0007617 20 0.011
Fly
sister chromatid segregation GO:0000819 20 0.011
regulation of protein kinase activity GO:0045859 232 0.011
striated muscle myosin thick filament assembly GO:0071688 1 0.011
cell activation involved in immune response GO:0002263 126 0.011
blastocyst development GO:0001824 80 0.011
regulation of chromosome organization GO:0033044 83 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
intracellular receptor signaling pathway GO:0030522 74 0.011
mesenchyme development GO:0060485 152 0.011
regulation of cell activation GO:0050865 289 0.011
negative regulation of molecular function GO:0044092 258 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
regulation of transmembrane transport GO:0034762 128 0.011
regulation of neuroblast proliferation GO:1902692 27 0.011
Fly
multicellular organismal signaling GO:0035637 91 0.011
negative regulation of synapse assembly GO:0051964 3 0.011
Fly
regulation of protein processing GO:0070613 96 0.011
regulation of proteasomal protein catabolic process GO:0061136 46 0.011
ossification GO:0001503 216 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
striated muscle cell development GO:0055002 125 0.011
Zebrafish
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
establishment of protein localization to organelle GO:0072594 118 0.010
lymphocyte mediated immunity GO:0002449 139 0.010
inorganic cation transmembrane transport GO:0098662 207 0.010
compound eye development GO:0048749 1 0.010
ras protein signal transduction GO:0007265 77 0.010
endocytosis GO:0006897 168 0.010
regulation of nucleocytoplasmic transport GO:0046822 73 0.010
sleep GO:0030431 7 0.010
Fly
negative regulation of cell proliferation GO:0008285 296 0.010
skeletal muscle organ development GO:0060538 163 0.010
Zebrafish
macromolecular complex disassembly GO:0032984 43 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.010
negative regulation of organelle organization GO:0010639 90 0.010
neuron death GO:0070997 154 0.010
endomembrane system organization GO:0010256 147 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
regulation of secretion by cell GO:1903530 249 0.010
developmental growth involved in morphogenesis GO:0060560 138 0.010

Fxr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.269
disease of anatomical entity DOID:7 0 0.269
nervous system disease DOID:863 0 0.269
neurodegenerative disease DOID:1289 0 0.051
reproductive system disease DOID:15 0 0.024
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
x linked disease DOID:0050735 0 0.011