Mus musculus

250 known processes

Fzd1

frizzled homolog 1 (Drosophila)

(Aliases: FZ-1,AW227548,Fz1)

Fzd1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
progesterone secretion GO:0042701 1 0.976
Mouse
blood vessel morphogenesis GO:0048514 285 0.959
Mouse
morphogenesis of a polarized epithelium GO:0001738 37 0.954
negative regulation of axon guidance GO:1902668 8 0.943
axon guidance GO:0007411 141 0.942
Mouse
establishment of tissue polarity GO:0007164 28 0.936
morphogenesis of a branching epithelium GO:0061138 193 0.934
Mouse
negative regulation of bmp signaling pathway GO:0030514 35 0.924
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.905
trunk neural crest cell migration GO:0036484 4 0.902
negative regulation of cell proliferation GO:0008285 296 0.891
Mouse
morphogenesis of a branching structure GO:0001763 203 0.887
Mouse
establishment of planar polarity GO:0001736 28 0.883
syncytiotrophoblast cell differentiation involved in labyrinthine layer development GO:0060715 2 0.881
Mouse
mesenchyme development GO:0060485 152 0.880
Mouse
axon extension involved in axon guidance GO:0048846 14 0.875
skeletal system development GO:0001501 356 0.870
Mouse
positive regulation of neuron projection development GO:0010976 79 0.840
neural tube formation GO:0001841 108 0.838
regulation of neuron differentiation GO:0045664 281 0.834
epithelial tube morphogenesis GO:0060562 303 0.831
positive regulation of nervous system development GO:0051962 221 0.827
Mouse
negative regulation of execution phase of apoptosis GO:1900118 4 0.817
Mouse
cerebellum vasculature morphogenesis GO:0061301 1 0.808
Mouse
primary neural tube formation GO:0014020 95 0.800
positive regulation of protein phosphorylation GO:0001934 242 0.793
wnt signaling pathway GO:0016055 188 0.792
mesonephric duct morphogenesis GO:0072180 4 0.792
segmentation GO:0035282 93 0.791
positive regulation of kinase activity GO:0033674 155 0.790
Mouse
ameboidal type cell migration GO:0001667 128 0.788
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.787
Mouse
positive regulation of cell development GO:0010720 237 0.771
Mouse
limb development GO:0060173 166 0.770
Mouse
embryonic digit morphogenesis GO:0042733 56 0.768
Mouse
ear development GO:0043583 200 0.762
Mouse
negative chemotaxis GO:0050919 14 0.759
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.751
branching morphogenesis of an epithelial tube GO:0048754 159 0.748
cerebellum vasculature development GO:0061300 1 0.747
Mouse
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.747
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.744
rho protein signal transduction GO:0007266 32 0.744
planar cell polarity pathway involved in neural tube closure GO:0090179 14 0.739
embryonic organ morphogenesis GO:0048562 276 0.730
Mouse
regionalization GO:0003002 337 0.726
ossification GO:0001503 216 0.721
Human Rat
regulation of ossification GO:0030278 112 0.718
Rat
regulation of transferase activity GO:0051338 263 0.715
Mouse
embryonic epithelial tube formation GO:0001838 130 0.710
chondrocyte differentiation GO:0002062 72 0.699
hindbrain development GO:0030902 128 0.697
Mouse
regulation of angiogenesis GO:0045765 81 0.694
regulation of cell migration GO:0030334 219 0.692
convergent extension GO:0060026 14 0.690
Mouse
nucleotide metabolic process GO:0009117 332 0.685
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.685
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.684
positive regulation of jun kinase activity GO:0043507 30 0.675
Mouse
angiogenesis GO:0001525 201 0.671
Mouse
epidermis development GO:0008544 187 0.666
Mouse
negative regulation of cell substrate adhesion GO:0010812 16 0.663
Mouse
regulation of axon guidance GO:1902667 13 0.662
chemotaxis GO:0006935 247 0.661
Mouse
stem cell differentiation GO:0048863 268 0.660
Human Mouse
neural tube closure GO:0001843 90 0.660
neuron projection guidance GO:0097485 141 0.657
Mouse
forebrain development GO:0030900 302 0.650
positive regulation of synapse assembly GO:0051965 18 0.640
sympathetic neuron projection guidance GO:0097491 4 0.637
cartilage development GO:0051216 140 0.636
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.634
pallium development GO:0021543 120 0.629
ear morphogenesis GO:0042471 118 0.624
Mouse
stress activated protein kinase signaling cascade GO:0031098 81 0.618
Mouse
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.615
positive regulation of cellular amine metabolic process GO:0033240 5 0.614
regulation of cell substrate adhesion GO:0010810 73 0.613
Mouse
renal system development GO:0072001 225 0.611
appendage development GO:0048736 166 0.609
Mouse
cell adhesion GO:0007155 329 0.608
Mouse
branchiomotor neuron axon guidance GO:0021785 7 0.607
epithelial tube formation GO:0072175 130 0.605
negative regulation of hepatocyte differentiation GO:0070367 1 0.598
Mouse
gland development GO:0048732 330 0.595
Mouse
t cell activation GO:0042110 289 0.595
Mouse
negative regulation of cell development GO:0010721 169 0.593
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.592
regulation of catenin import into nucleus GO:0035412 5 0.592
tube closure GO:0060606 91 0.588
myeloid cell differentiation GO:0030099 233 0.583
regulation of nucleotide metabolic process GO:0006140 169 0.583
t cell differentiation in thymus GO:0033077 77 0.579
Mouse
sympathetic neuron projection extension GO:0097490 4 0.578
embryonic nail plate morphogenesis GO:0035880 3 0.578
Mouse
neuron migration GO:0001764 122 0.577
Mouse
developmental maturation GO:0021700 193 0.576
Mouse
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.573
female gonad development GO:0008585 71 0.568
Mouse
bone development GO:0060348 120 0.558
purine nucleotide metabolic process GO:0006163 302 0.557
positive regulation of mapk cascade GO:0043410 170 0.557
Mouse
central nervous system neuron development GO:0021954 67 0.556
single organism cell adhesion GO:0098602 156 0.551
Mouse
mesonephric tubule development GO:0072164 94 0.548
mesenchymal cell differentiation GO:0048762 107 0.544
Mouse
sympathetic nervous system development GO:0048485 22 0.542
Mouse
maintenance of cell number GO:0098727 3 0.542
Mouse
somite development GO:0061053 81 0.538
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.531
Human Mouse Rat
leukocyte differentiation GO:0002521 342 0.530
Mouse
regulation of hormone levels GO:0010817 211 0.529
Mouse
embryonic skeletal system morphogenesis GO:0048704 91 0.528
palate development GO:0060021 76 0.526
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.524
regulation of cartilage development GO:0061035 44 0.524
Mouse
digestive tract morphogenesis GO:0048546 147 0.523
skin development GO:0043588 220 0.522
Mouse
embryonic skeletal system development GO:0048706 120 0.519
cytokine production GO:0001816 319 0.517
autonomic nervous system development GO:0048483 43 0.514
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.512
negative regulation of chemotaxis GO:0050922 11 0.511
negative regulation of growth GO:0045926 99 0.509
regulation of protein kinase activity GO:0045859 232 0.509
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.507
regulation of cell adhesion GO:0030155 154 0.507
Mouse
neural tube development GO:0021915 160 0.505
regulation of vasculature development GO:1901342 88 0.501
embryonic appendage morphogenesis GO:0035113 126 0.501
Mouse
gtp catabolic process GO:0006184 143 0.499
cell proliferation in midbrain GO:0033278 2 0.497
Mouse
skeletal system morphogenesis GO:0048705 203 0.495
somitogenesis GO:0001756 69 0.494
purine ribonucleotide metabolic process GO:0009150 290 0.481
regulation of rho gtpase activity GO:0032319 58 0.480
regulation of cell activation GO:0050865 289 0.478
telencephalon development GO:0021537 186 0.477
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.476
negative regulation of epithelial cell proliferation GO:0050680 64 0.475
mapk cascade GO:0000165 281 0.475
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.474
regulation of establishment of planar polarity GO:0090175 28 0.473
synapse assembly GO:0007416 56 0.470
stem cell development GO:0048864 219 0.464
neuroblast proliferation GO:0007405 49 0.459
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.458
epithelial cell proliferation GO:0050673 174 0.456
ribose phosphate metabolic process GO:0019693 291 0.454
cellular amino acid metabolic process GO:0006520 103 0.453
forebrain neuron differentiation GO:0021879 52 0.452
regulation of anatomical structure size GO:0090066 178 0.448
negative regulation of nervous system development GO:0051961 156 0.442
gastrulation GO:0007369 116 0.438
regulation of body fluid levels GO:0050878 162 0.434
Mouse
smoothened signaling pathway GO:0007224 105 0.434
regulation of tight junction assembly GO:2000810 2 0.433
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.432
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.425
negative regulation of cartilage development GO:0061037 17 0.424
Mouse
cardiac chamber development GO:0003205 108 0.424
retinal blood vessel morphogenesis GO:0061304 3 0.422
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.419
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.418
regulation of cytoskeleton organization GO:0051493 122 0.416
sensory organ morphogenesis GO:0090596 242 0.416
Mouse
ribonucleotide metabolic process GO:0009259 291 0.413
mesenchymal cell development GO:0014031 93 0.410
regulation of neuron projection development GO:0010975 169 0.409
urogenital system development GO:0001655 261 0.409
non canonical wnt signaling pathway GO:0035567 33 0.405
chondrocyte development GO:0002063 24 0.404
negative regulation of axon extension GO:0030517 19 0.403
synapse organization GO:0050808 125 0.402
appendage morphogenesis GO:0035107 149 0.402
Mouse
regulation of cell motility GO:2000145 236 0.400
semaphorin plexin signaling pathway involved in bone trabecula morphogenesis GO:1900220 2 0.397
morphogenesis of embryonic epithelium GO:0016331 159 0.396
regulation of ras gtpase activity GO:0032318 88 0.394
chorionic trophoblast cell proliferation GO:0097360 1 0.393
Mouse
hair cycle GO:0042633 90 0.393
Mouse
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.393
positive regulation of map kinase activity GO:0043406 84 0.392
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.391
purine nucleoside metabolic process GO:0042278 241 0.390
ribonucleoside metabolic process GO:0009119 245 0.384
protein kinase b signaling GO:0043491 74 0.383
ras protein signal transduction GO:0007265 77 0.382
establishment of protein localization to organelle GO:0072594 118 0.379
positive regulation of jnk cascade GO:0046330 46 0.379
Mouse
stem cell proliferation GO:0072089 117 0.377
Mouse
blastoderm segmentation GO:0007350 13 0.376
positive regulation of protein modification process GO:0031401 299 0.371
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.370
neural crest cell differentiation GO:0014033 54 0.369
Mouse
trachea cartilage morphogenesis GO:0060535 4 0.368
peptidyl amino acid modification GO:0018193 336 0.367
cell fate commitment GO:0045165 210 0.366
forebrain neuron development GO:0021884 30 0.365
organonitrogen compound catabolic process GO:1901565 264 0.365
regulation of cellular component size GO:0032535 121 0.362
ureteric bud development GO:0001657 94 0.360
nucleoside phosphate metabolic process GO:0006753 338 0.359
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.358
regulation of organ morphogenesis GO:2000027 144 0.358
t cell differentiation GO:0030217 174 0.357
Mouse
regulation of system process GO:0044057 200 0.357
fat cell differentiation GO:0045444 160 0.355
embryonic placenta development GO:0001892 98 0.355
Mouse
negative regulation of prostatic bud formation GO:0060686 4 0.354
negative regulation of synapse assembly GO:0051964 3 0.353
purine nucleoside triphosphate catabolic process GO:0009146 203 0.352
glycosyl compound catabolic process GO:1901658 206 0.348
axis elongation involved in somitogenesis GO:0090245 4 0.347
sensory perception GO:0007600 245 0.346
Mouse
aromatic compound catabolic process GO:0019439 286 0.345
mesonephric epithelium development GO:0072163 94 0.342
positive regulation of protein kinase activity GO:0045860 144 0.342
Mouse
negative regulation of cell migration GO:0030336 59 0.342
tight junction assembly GO:0070830 9 0.342
Mouse
regulation of mapk cascade GO:0043408 248 0.341
Mouse
connective tissue development GO:0061448 179 0.341
Mouse
stem cell division GO:0017145 30 0.339
Mouse
kidney development GO:0001822 213 0.337
regulation of actin cytoskeleton organization GO:0032956 84 0.337
positive regulation of neuron differentiation GO:0045666 141 0.333
muscle tissue development GO:0060537 308 0.333
negative regulation of catenin import into nucleus GO:0035414 2 0.333
germ cell development GO:0007281 185 0.332
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.331
gonad development GO:0008406 141 0.328
Mouse
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.326
purine containing compound metabolic process GO:0072521 311 0.325
cardiac chamber morphogenesis GO:0003206 93 0.325
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.324
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.321
response to organonitrogen compound GO:0010243 246 0.320
Rat
purine containing compound catabolic process GO:0072523 213 0.319
regulation of establishment of protein localization GO:0070201 181 0.318
negative regulation of mitotic cell cycle embryonic GO:0045976 2 0.318
Mouse
regulation of protein localization GO:0032880 231 0.316
single organismal cell cell adhesion GO:0016337 131 0.315
digestive system development GO:0055123 200 0.313
small gtpase mediated signal transduction GO:0007264 97 0.312
embryonic limb morphogenesis GO:0030326 126 0.311
Mouse
regulation of chemotaxis GO:0050920 53 0.311
forebrain generation of neurons GO:0021872 63 0.309
substrate dependent cerebral cortex tangential migration GO:0021825 3 0.308
regulation of bmp signaling pathway GO:0030510 60 0.308
endothelial cell differentiation GO:0045446 41 0.307
nucleoside triphosphate metabolic process GO:0009141 230 0.306
apoptotic signaling pathway GO:0097190 306 0.305
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.305
regulation of purine nucleotide metabolic process GO:1900542 169 0.304
skeletal muscle tissue regeneration GO:0043403 20 0.304
Mouse
negative regulation of neuron projection development GO:0010977 50 0.299
hormone secretion GO:0046879 128 0.299
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.297
Mouse
polarity specification of proximal distal axis GO:0010085 2 0.296
central nervous system neuron differentiation GO:0021953 162 0.296
nucleotide catabolic process GO:0009166 217 0.294
positive regulation of ossification GO:0045778 47 0.294
cellular amine metabolic process GO:0044106 44 0.294
camera type eye development GO:0043010 266 0.292
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.291
hair follicle development GO:0001942 85 0.291
Mouse
negative regulation of cell growth GO:0030308 44 0.290
positive regulation of gtpase activity GO:0043547 85 0.289
regulation of extent of cell growth GO:0061387 52 0.289
actin filament organization GO:0007015 113 0.288
ribonucleoside catabolic process GO:0042454 206 0.287
ribonucleoside triphosphate metabolic process GO:0009199 220 0.286
ventral trunk neural crest cell migration GO:0036486 4 0.285
cell division GO:0051301 120 0.283
Mouse
semaphorin plexin signaling pathway involved in axon guidance GO:1902287 6 0.283
sympathetic ganglion development GO:0061549 9 0.279
Mouse
foregut regionalization GO:0060423 3 0.279
limb morphogenesis GO:0035108 149 0.277
Mouse
canonical wnt signaling pathway GO:0060070 130 0.277
gtp metabolic process GO:0046039 144 0.276
positive regulation of stem cell proliferation GO:2000648 59 0.274
Mouse
developmental cell growth GO:0048588 84 0.273
endothelial cell migration GO:0043542 44 0.272
negative regulation of immune system process GO:0002683 209 0.271
regulation of axon extension GO:0030516 43 0.271
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.270
Human Mouse Rat
regulation of jnk cascade GO:0046328 62 0.269
Mouse
positive regulation of cell migration GO:0030335 109 0.268
semaphorin plexin signaling pathway involved in neuron projection guidance GO:1902285 6 0.268
purine ribonucleoside catabolic process GO:0046130 205 0.267
hypothalamic tangential migration using cell axon interactions GO:0021856 3 0.266
regulation of cellular ketone metabolic process GO:0010565 66 0.265
stem cell maintenance GO:0019827 130 0.264
regulation of cell projection organization GO:0031344 206 0.264
muscle cell differentiation GO:0042692 261 0.264
regulation of chondrocyte differentiation GO:0032330 33 0.260
cardiac septum morphogenesis GO:0060411 46 0.259
digestive tract development GO:0048565 190 0.259
regulation of cell growth GO:0001558 91 0.259
positive regulation of cell activation GO:0050867 158 0.258
regulation of response to wounding GO:1903034 189 0.258
lens development in camera type eye GO:0002088 62 0.257
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.257
trunk segmentation GO:0035290 4 0.255
positive regulation of neuroblast proliferation GO:0002052 19 0.255
Mouse
regulation of peptidyl serine phosphorylation GO:0033135 39 0.254
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.254
regulation of protein kinase b signaling GO:0051896 56 0.253
axonogenesis GO:0007409 274 0.252
Mouse
locomotory behavior GO:0007626 195 0.251
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.251
hepaticobiliary system development GO:0061008 67 0.250
Mouse
stress activated mapk cascade GO:0051403 80 0.250
Mouse
regulation of neural precursor cell proliferation GO:2000177 70 0.246
Mouse
protein catabolic process GO:0030163 221 0.246
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.245
muscular septum morphogenesis GO:0003150 4 0.245
regulation of hydrolase activity GO:0051336 246 0.244
negative regulation of hormone biosynthetic process GO:0032353 4 0.244
skin morphogenesis GO:0043589 38 0.243
mesonephric tubule morphogenesis GO:0072171 63 0.243
regulation of cellular response to stress GO:0080135 159 0.241
Mouse
negative regulation of blood vessel morphogenesis GO:2000181 25 0.241
cell migration involved in gastrulation GO:0042074 13 0.240
glycosyl compound metabolic process GO:1901657 246 0.239
regulation of organelle organization GO:0033043 289 0.238
cardiac septum development GO:0003279 59 0.238
labyrinthine layer development GO:0060711 49 0.236
Mouse
neural precursor cell proliferation GO:0061351 121 0.235
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.234
post anal tail morphogenesis GO:0036342 23 0.233
Mouse
lymphocyte differentiation GO:0030098 242 0.233
Mouse
cell maturation GO:0048469 127 0.233
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.231
cell growth GO:0016049 130 0.231
artery development GO:0060840 53 0.230
molting cycle GO:0042303 90 0.229
Mouse
facial nerve structural organization GO:0021612 10 0.229
positive regulation of rho gtpase activity GO:0032321 41 0.228
paraxial mesodermal cell fate commitment GO:0048343 2 0.228
negative regulation of phosphorylation GO:0042326 166 0.228
lipid localization GO:0010876 126 0.225
Mouse
extracellular matrix organization GO:0030198 147 0.225
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.225
development of primary sexual characteristics GO:0045137 143 0.223
Mouse
regulation of protein import into nucleus GO:0042306 52 0.222
regeneration GO:0031099 38 0.218
Mouse
dendritic spine organization GO:0097061 26 0.218
regulation of osteoblast differentiation GO:0045667 67 0.218
Rat
negative regulation of apoptotic signaling pathway GO:2001234 104 0.217
kidney epithelium development GO:0072073 121 0.217
positive regulation of cell projection organization GO:0031346 95 0.216
nephron tubule development GO:0072080 84 0.215
negative regulation of neuron differentiation GO:0045665 101 0.215
tube formation GO:0035148 140 0.215
regulation of kinase activity GO:0043549 249 0.214
Mouse
regulation of chorionic trophoblast cell proliferation GO:1901382 1 0.214
Mouse
regulation of t cell proliferation GO:0042129 92 0.214
limbic system development GO:0021761 72 0.213
regulation of hormone secretion GO:0046883 88 0.212
lymphocyte proliferation GO:0046651 164 0.212
development of primary male sexual characteristics GO:0046546 88 0.211
guanosine containing compound metabolic process GO:1901068 144 0.211
bmp signaling pathway GO:0030509 93 0.210
coagulation GO:0050817 78 0.209
Mouse
positive regulation of stress activated mapk cascade GO:0032874 48 0.209
Mouse
apical junction assembly GO:0043297 15 0.207
Mouse
neural crest cell migration GO:0001755 32 0.207
apoptotic process involved in morphogenesis GO:0060561 25 0.207
Mouse
peptide secretion GO:0002790 114 0.206
paraxial mesoderm morphogenesis GO:0048340 10 0.205
single organism nuclear import GO:1902593 95 0.201
negative regulation of phosphate metabolic process GO:0045936 184 0.200
positive regulation of apoptotic process GO:0043065 217 0.199
regulation of stress activated mapk cascade GO:0032872 69 0.198
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.198
tissue migration GO:0090130 68 0.198
negative regulation of behavior GO:0048521 14 0.197
epithelial cell migration GO:0010631 63 0.197
negative regulation of cell motility GO:2000146 61 0.196
regulation of stem cell proliferation GO:0072091 78 0.196
Mouse
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.196
nephron tubule morphogenesis GO:0072078 68 0.196
cardiac epithelial to mesenchymal transition GO:0060317 18 0.195
cellular protein catabolic process GO:0044257 155 0.194
b cell activation GO:0042113 161 0.193
Mouse
oviduct development GO:0060066 3 0.193
regulation of cell cycle GO:0051726 281 0.192
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.191
organophosphate catabolic process GO:0046434 232 0.191
smooth muscle cell migration GO:0014909 10 0.190
synaptic transmission GO:0007268 329 0.190
regulation of purine nucleotide catabolic process GO:0033121 122 0.190
smooth muscle tissue development GO:0048745 22 0.189
ubiquitin dependent protein catabolic process GO:0006511 129 0.188
positive regulation of cellular catabolic process GO:0031331 148 0.187
extrinsic apoptotic signaling pathway GO:0097191 126 0.187
cardiac muscle tissue development GO:0048738 130 0.187
nuclear import GO:0051170 95 0.186
negative regulation of angiogenesis GO:0016525 25 0.185
cerebral cortex development GO:0021987 86 0.185
nucleoside metabolic process GO:0009116 246 0.184
peptidyl serine phosphorylation GO:0018105 74 0.184
striated muscle tissue development GO:0014706 293 0.184
epithelium migration GO:0090132 63 0.184
cerebellar granule cell precursor tangential migration GO:0021935 1 0.183
regulation of epithelial cell migration GO:0010632 35 0.182
placenta development GO:0001890 140 0.181
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.181
Mouse
central nervous system vasculogenesis GO:0022009 3 0.180
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.179
positive regulation of osteoblast differentiation GO:0045669 34 0.179
regulation of wnt signaling pathway GO:0030111 123 0.179
cellular ketone metabolic process GO:0042180 84 0.179
respiratory system development GO:0060541 190 0.178
Rat
bone mineralization GO:0030282 54 0.178
positive regulation of lymphocyte activation GO:0051251 140 0.177
purine nucleoside catabolic process GO:0006152 205 0.177
negative regulation of phosphorus metabolic process GO:0010563 184 0.175
regulation of cellular catabolic process GO:0031329 242 0.175
positive regulation of neural precursor cell proliferation GO:2000179 42 0.174
Mouse
regulation of smoothened signaling pathway GO:0008589 58 0.173
regulation of ketone biosynthetic process GO:0010566 2 0.172
negative regulation of protein phosphorylation GO:0001933 126 0.171
tissue regeneration GO:0042246 22 0.170
Mouse
mesenchymal cell proliferation GO:0010463 44 0.170
negative regulation of response to wounding GO:1903035 77 0.169
mesonephros development GO:0001823 97 0.169
regulation of rho protein signal transduction GO:0035023 71 0.168
motor neuron axon guidance GO:0008045 26 0.168
negative regulation of protein metabolic process GO:0051248 282 0.168
female sex differentiation GO:0046660 84 0.168
Mouse
neural crest cell development GO:0014032 48 0.167
positive regulation of ras gtpase activity GO:0032320 65 0.167
anatomical structure arrangement GO:0048532 20 0.167
midbrain development GO:0030901 35 0.167
Mouse
positive regulation of cell proliferation involved in heart valve morphogenesis GO:0003251 1 0.166
inflammatory response GO:0006954 244 0.165
actin cytoskeleton organization GO:0030036 220 0.165
retinal ganglion cell axon guidance GO:0031290 18 0.164
hippocampus development GO:0021766 52 0.164
cell substrate adhesion GO:0031589 130 0.163
Mouse
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.163
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.162
male sex differentiation GO:0046661 109 0.161
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.161
regulation of gtp catabolic process GO:0033124 113 0.159
trabecula morphogenesis GO:0061383 40 0.159
positive regulation of transferase activity GO:0051347 167 0.158
Mouse
negative regulation of vasculature development GO:1901343 26 0.158
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.158
spinal cord development GO:0021510 81 0.158
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.157
regulation of lymphocyte activation GO:0051249 240 0.157
regulation of leukocyte proliferation GO:0070663 121 0.157
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.157
positive regulation of smoothened signaling pathway GO:0045880 23 0.156
sensory perception of chemical stimulus GO:0007606 51 0.155
Mouse
carbohydrate homeostasis GO:0033500 128 0.155
regulation of synapse assembly GO:0051963 29 0.153
regulation of intracellular protein transport GO:0033157 82 0.152
cellular response to molecule of bacterial origin GO:0071219 83 0.152
negative regulation of cellular component organization GO:0051129 194 0.151
regulation of nucleotide catabolic process GO:0030811 122 0.151
labyrinthine layer blood vessel development GO:0060716 21 0.151
Mouse
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.151
bone morphogenesis GO:0060349 78 0.150
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.150
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.150
positive regulation of cytokine production GO:0001819 174 0.149
kidney morphogenesis GO:0060993 83 0.149
photoreceptor cell development GO:0042461 40 0.149
positive regulation of organelle organization GO:0010638 128 0.148
cerebellum development GO:0021549 77 0.147
Mouse
cellular homeostasis GO:0019725 240 0.147
myeloid leukocyte differentiation GO:0002573 119 0.146
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.146
glial cell differentiation GO:0010001 131 0.146
amide transport GO:0042886 138 0.146
positive regulation of cell growth GO:0030307 33 0.144
hypothalamus gonadotrophin releasing hormone neuron development GO:0021888 4 0.144
nuclear transport GO:0051169 139 0.144
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.143
nucleoside catabolic process GO:0009164 206 0.142
regulation of embryonic development GO:0045995 71 0.142
endocytosis GO:0006897 168 0.141
negative regulation of wnt signaling pathway GO:0030178 73 0.141
amine metabolic process GO:0009308 45 0.140
protein localization to organelle GO:0033365 185 0.140
cellular chemical homeostasis GO:0055082 215 0.140
regulation of secretion GO:0051046 274 0.138
endocrine system development GO:0035270 98 0.138
jnk cascade GO:0007254 72 0.137
Mouse
nephron development GO:0072006 109 0.137
purine nucleotide catabolic process GO:0006195 211 0.136
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.136
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.136
epithelial to mesenchymal transition GO:0001837 47 0.135
protein modification by small protein conjugation or removal GO:0070647 207 0.135
positive regulation of interleukin 8 secretion GO:2000484 1 0.134

Fzd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org