Mus musculus

0 known processes

Gabbr2

gamma-aminobutyric acid (GABA) B receptor, 2

(Aliases: Gb2,Gm425,GABABR2,Gpr51)

Gabbr2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of dopamine secretion GO:0014059 9 0.565
regulation of gamma aminobutyric acid secretion GO:0014052 2 0.409
negative regulation of nucleotide metabolic process GO:0045980 16 0.389
positive regulation of growth hormone secretion GO:0060124 3 0.382
regulation of catecholamine secretion GO:0050433 12 0.371
gamma aminobutyric acid signaling pathway GO:0007214 8 0.344
Mouse Rat
negative regulation of cyclic nucleotide metabolic process GO:0030800 5 0.327
g protein coupled receptor signaling pathway GO:0007186 243 0.326
Mouse Rat
amino acid transport GO:0006865 61 0.296
positive regulation of amine transport GO:0051954 8 0.269
purine ribonucleotide biosynthetic process GO:0009152 59 0.258
camp metabolic process GO:0046058 40 0.247
nucleoside phosphate biosynthetic process GO:1901293 79 0.240
regulation of camp biosynthetic process GO:0030817 25 0.225
nucleoside phosphate metabolic process GO:0006753 338 0.225
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.216
carbohydrate derivative biosynthetic process GO:1901137 183 0.216
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.212
gamma aminobutyric acid secretion GO:0014051 6 0.199
dopamine secretion GO:0014046 9 0.193
catecholamine secretion GO:0050432 15 0.188
purine nucleotide biosynthetic process GO:0006164 65 0.181
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.180
anion transport GO:0006820 177 0.178
epinephrine transport GO:0048241 1 0.173
ribonucleotide biosynthetic process GO:0009260 59 0.165
cyclic nucleotide metabolic process GO:0009187 59 0.160
organic acid transport GO:0015849 101 0.160
negative regulation of lyase activity GO:0051350 1 0.158
organophosphate biosynthetic process GO:0090407 122 0.153
regulation of peptide secretion GO:0002791 77 0.145
cyclic purine nucleotide metabolic process GO:0052652 43 0.139
regulation of purine nucleotide metabolic process GO:1900542 169 0.135
cation transport GO:0006812 399 0.133
negative regulation of phosphorus metabolic process GO:0010563 184 0.130
regulation of glutamate secretion GO:0014048 3 0.128
purine nucleotide metabolic process GO:0006163 302 0.125
positive regulation of glutamate secretion GO:0014049 2 0.124
nucleobase containing small molecule metabolic process GO:0055086 352 0.117
organic hydroxy compound transport GO:0015850 93 0.116
nucleotide metabolic process GO:0009117 332 0.116
regulation of nucleotide metabolic process GO:0006140 169 0.111
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.109
regulation of nucleotide biosynthetic process GO:0030808 34 0.104
synaptic transmission GO:0007268 329 0.101
negative regulation of molecular function GO:0044092 258 0.093
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.093
negative regulation of adenylate cyclase activity GO:0007194 1 0.092
ribose phosphate biosynthetic process GO:0046390 59 0.091
regulation of anion transport GO:0044070 27 0.090
purine ribonucleotide metabolic process GO:0009150 290 0.090
regulation of ion transport GO:0043269 215 0.089
neurotransmitter secretion GO:0007269 62 0.087
camp biosynthetic process GO:0006171 31 0.086
dopamine transport GO:0015872 15 0.083
gamma aminobutyric acid transport GO:0015812 7 0.082
regulation of secretion GO:0051046 274 0.078
catecholamine transport GO:0051937 21 0.077
positive regulation of amino acid transport GO:0051957 4 0.076
positive regulation of hormone secretion GO:0046887 38 0.075
amine transport GO:0015837 21 0.072
circulatory system process GO:0003013 197 0.072
regulation of hormone levels GO:0010817 211 0.069
regulation of peptide hormone secretion GO:0090276 75 0.068
ossification GO:0001503 216 0.068
negative regulation of cell proliferation GO:0008285 296 0.067
negative regulation of secretion GO:0051048 61 0.066
ras protein signal transduction GO:0007265 77 0.065
response to organic cyclic compound GO:0014070 198 0.065
positive regulation of peptide hormone secretion GO:0090277 31 0.063
epinephrine secretion GO:0048242 1 0.063
purine containing compound metabolic process GO:0072521 311 0.062
purine containing compound biosynthetic process GO:0072522 70 0.062
positive regulation of secretion GO:0051047 130 0.058
negative regulation of cyclase activity GO:0031280 1 0.057
dicarboxylic acid transport GO:0006835 29 0.057
nitrogen compound transport GO:0071705 271 0.055
cyclic nucleotide biosynthetic process GO:0009190 44 0.055
carboxylic acid transport GO:0046942 100 0.054
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.054
hormone secretion GO:0046879 128 0.053
amide transport GO:0042886 138 0.051
positive regulation of peptide secretion GO:0002793 33 0.051
organonitrogen compound biosynthetic process GO:1901566 192 0.050
nucleotide biosynthetic process GO:0009165 78 0.050
negative regulation of secretion by cell GO:1903531 54 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.049
multicellular organismal signaling GO:0035637 91 0.047
peptide secretion GO:0002790 114 0.047
transmission of nerve impulse GO:0019226 76 0.046
acid secretion GO:0046717 33 0.045
regulation of cyclase activity GO:0031279 13 0.045
cellular amino acid metabolic process GO:0006520 103 0.044
regulation of amine transport GO:0051952 21 0.043
monocarboxylic acid transport GO:0015718 44 0.043
carbohydrate derivative catabolic process GO:1901136 231 0.042
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
response to alkaloid GO:0043279 34 0.041
purine ribonucleoside metabolic process GO:0046128 241 0.040
regulation of peptide transport GO:0090087 91 0.040
regulation of camp metabolic process GO:0030814 30 0.040
regulation of organic acid transport GO:0032890 16 0.040
monoamine transport GO:0015844 33 0.039
regulation of secretion by cell GO:1903530 249 0.039
response to ethanol GO:0045471 18 0.038
regulation of hormone secretion GO:0046883 88 0.038
ribose phosphate metabolic process GO:0019693 291 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.038
negative regulation of camp metabolic process GO:0030815 5 0.037
locomotory behavior GO:0007626 195 0.037
nucleoside metabolic process GO:0009116 246 0.037
response to organonitrogen compound GO:0010243 246 0.037
regulation of growth hormone secretion GO:0060123 5 0.037
response to alcohol GO:0097305 48 0.037
cellular ion homeostasis GO:0006873 165 0.037
regulation of lyase activity GO:0051339 13 0.036
cell adhesion GO:0007155 329 0.034
regulation of cellular amino acid metabolic process GO:0006521 5 0.033
regulation of cell projection organization GO:0031344 206 0.033
glutamate secretion GO:0014047 8 0.033
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.033
ribonucleotide catabolic process GO:0009261 208 0.033
neurotransmitter transport GO:0006836 76 0.032
positive regulation of organic acid transport GO:0032892 11 0.032
purine nucleoside triphosphate metabolic process GO:0009144 226 0.031
protein maturation GO:0051604 176 0.031
regulation of membrane potential GO:0042391 192 0.030
purine nucleoside triphosphate catabolic process GO:0009146 203 0.030
glycosyl compound metabolic process GO:1901657 246 0.030
divalent inorganic cation homeostasis GO:0072507 138 0.030
growth hormone secretion GO:0030252 9 0.030
regulation of anatomical structure size GO:0090066 178 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
peptidyl amino acid modification GO:0018193 336 0.029
polarity specification of proximal distal axis GO:0010085 2 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.029
organic cyclic compound catabolic process GO:1901361 295 0.028
negative regulation of purine nucleotide biosynthetic process GO:1900372 6 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.027
response to nicotine GO:0035094 6 0.027
cellular response to lipid GO:0071396 145 0.027
memory GO:0007613 58 0.026
regulation of purine nucleotide catabolic process GO:0033121 122 0.026
purine containing compound catabolic process GO:0072523 213 0.025
negative regulation of synapse assembly GO:0051964 3 0.025
negative regulation of ion transport GO:0043271 28 0.025
negative regulation of cellular component organization GO:0051129 194 0.025
divalent inorganic cation transport GO:0072511 178 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.024
regulation of hydrolase activity GO:0051336 246 0.024
membrane organization GO:0061024 245 0.024
cellular lipid metabolic process GO:0044255 323 0.024
cellular response to hormone stimulus GO:0032870 150 0.024
nucleoside monophosphate metabolic process GO:0009123 85 0.024
regulation of peptidase activity GO:0052547 96 0.024
peptide transport GO:0015833 133 0.023
protein modification by small protein conjugation GO:0032446 187 0.023
central nervous system neuron differentiation GO:0021953 162 0.023
regulation of blood pressure GO:0008217 93 0.023
ribonucleoside catabolic process GO:0042454 206 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
apoptotic signaling pathway GO:0097190 306 0.023
regulation of system process GO:0044057 200 0.022
kidney development GO:0001822 213 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
protein ubiquitination GO:0016567 171 0.022
calcium ion homeostasis GO:0055074 127 0.022
forebrain development GO:0030900 302 0.022
cation homeostasis GO:0055080 212 0.022
cellular metal ion homeostasis GO:0006875 151 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
protein processing GO:0016485 163 0.021
gland development GO:0048732 330 0.021
cellular response to organic cyclic compound GO:0071407 87 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
calcium ion transmembrane transport GO:0070588 85 0.021
positive regulation of leukocyte differentiation GO:1902107 86 0.020
peptide hormone secretion GO:0030072 109 0.020
sensory organ morphogenesis GO:0090596 242 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
cellular homeostasis GO:0019725 240 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
microtubule based process GO:0007017 236 0.020
renal system development GO:0072001 225 0.019
regulation of neurotransmitter levels GO:0001505 87 0.019
male gamete generation GO:0048232 285 0.019
embryonic organ morphogenesis GO:0048562 276 0.019
regulation of proteolysis GO:0030162 164 0.019
muscle tissue development GO:0060537 308 0.019
divalent metal ion transport GO:0070838 172 0.019
regulation of adenylate cyclase activity GO:0045761 10 0.019
negative regulation of camp biosynthetic process GO:0030818 5 0.019
adult behavior GO:0030534 135 0.019
fat cell differentiation GO:0045444 160 0.018
regulation of organelle organization GO:0033043 289 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
neuronal action potential GO:0019228 54 0.018
action potential GO:0001508 78 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.018
cellular ketone metabolic process GO:0042180 84 0.018
leukocyte apoptotic process GO:0071887 71 0.018
lung development GO:0030324 164 0.017
chromatin organization GO:0006325 206 0.017
muscle system process GO:0003012 141 0.017
cell growth GO:0016049 130 0.017
blood circulation GO:0008015 195 0.017
epithelial cell development GO:0002064 159 0.017
oocyte axis specification GO:0007309 2 0.017
aromatic compound catabolic process GO:0019439 286 0.017
carbohydrate metabolic process GO:0005975 230 0.017
positive regulation of cell death GO:0010942 224 0.017
positive regulation of proteolysis GO:0045862 85 0.017
calcium ion transport GO:0006816 159 0.016
intracellular mrna localization GO:0008298 4 0.016
developmental maturation GO:0021700 193 0.016
histone modification GO:0016570 159 0.016
neuron apoptotic process GO:0051402 142 0.016
cation transmembrane transport GO:0098655 266 0.016
response to light stimulus GO:0009416 135 0.016
skeletal system development GO:0001501 356 0.016
myotube differentiation GO:0014902 105 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
maternal determination of anterior posterior axis embryo GO:0008358 2 0.015
negative regulation of cell cycle GO:0045786 123 0.015
cell type specific apoptotic process GO:0097285 268 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.015
lipid biosynthetic process GO:0008610 179 0.015
lymphocyte apoptotic process GO:0070227 54 0.015
regulation of ossification GO:0030278 112 0.015
germ cell development GO:0007281 185 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
endomembrane system organization GO:0010256 147 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
regulation of vesicle mediated transport GO:0060627 139 0.014
negative regulation of nervous system development GO:0051961 156 0.014
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.014
amine metabolic process GO:0009308 45 0.014
sensory perception GO:0007600 245 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
regulation of transmembrane transport GO:0034762 128 0.014
nucleotide catabolic process GO:0009166 217 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
fertilization GO:0009566 127 0.014
cell recognition GO:0008037 83 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
camera type eye development GO:0043010 266 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
sulfur compound metabolic process GO:0006790 100 0.014
regulation of cell cycle GO:0051726 281 0.014
hormone metabolic process GO:0042445 86 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
leukocyte proliferation GO:0070661 172 0.014
skeletal muscle fiber development GO:0048741 58 0.014
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 5 0.014
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
pole plasm assembly GO:0007315 2 0.014
behavioral response to nicotine GO:0035095 5 0.013
regulation of protein processing GO:0070613 96 0.013
t cell activation GO:0042110 289 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
neuromuscular synaptic transmission GO:0007274 16 0.013
heart morphogenesis GO:0003007 178 0.013
negative regulation of cell development GO:0010721 169 0.013
potassium ion transport GO:0006813 52 0.013
regulation of cell adhesion GO:0030155 154 0.013
multicellular organism growth GO:0035264 161 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
regulation of nucleoside metabolic process GO:0009118 130 0.013
lateral inhibition GO:0046331 1 0.013
regulation of cellular component size GO:0032535 121 0.013
respiratory tube development GO:0030323 167 0.013
transmembrane transport GO:0055085 412 0.013
spermatogenesis GO:0007283 284 0.013
proteasomal protein catabolic process GO:0010498 98 0.013
gtp catabolic process GO:0006184 143 0.013
positive regulation of ion transport GO:0043270 65 0.013
compound eye development GO:0048749 1 0.013
macromolecule catabolic process GO:0009057 281 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.013
pigmentation GO:0043473 71 0.013
negative regulation of protein processing GO:0010955 79 0.013
epidermis development GO:0008544 187 0.013
epithelial tube morphogenesis GO:0060562 303 0.012
cellular protein complex assembly GO:0043623 116 0.012
positive regulation of protein modification process GO:0031401 299 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
regulation of protein maturation GO:1903317 96 0.012
regulation of cell activation GO:0050865 289 0.012
regulation of gtp catabolic process GO:0033124 113 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.012
cytokine production GO:0001816 319 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
synapse organization GO:0050808 125 0.012
regulation of neurotransmitter secretion GO:0046928 29 0.012
cellular protein catabolic process GO:0044257 155 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
regulation of cell cycle process GO:0010564 160 0.012
protein targeting GO:0006605 143 0.012
oocyte anterior posterior axis specification GO:0007314 2 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
positive regulation of peptidase activity GO:0010952 49 0.012
alpha beta t cell activation GO:0046631 91 0.012
glycoprotein metabolic process GO:0009100 116 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
adaptive immune response GO:0002250 155 0.011
developmental cell growth GO:0048588 84 0.011
chemotaxis GO:0006935 247 0.011
anatomical structure homeostasis GO:0060249 145 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
regulation of endopeptidase activity GO:0052548 89 0.011
organic anion transport GO:0015711 137 0.011
rhythmic process GO:0048511 174 0.011
response to acid chemical GO:0001101 111 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
regulation of protein localization GO:0032880 231 0.011
connective tissue development GO:0061448 179 0.011
atp metabolic process GO:0046034 75 0.011
nucleoside catabolic process GO:0009164 206 0.011
macromolecule methylation GO:0043414 120 0.011
negative regulation of protein modification process GO:0031400 163 0.011
skin development GO:0043588 220 0.011
mitochondrion organization GO:0007005 134 0.011
oxidation reduction process GO:0055114 342 0.011
nuclear division GO:0000280 158 0.011
positive regulation of cell development GO:0010720 237 0.011
negative regulation of immune system process GO:0002683 209 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
tendon formation GO:0035992 4 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
negative regulation of hydrolase activity GO:0051346 71 0.011
protein alkylation GO:0008213 81 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
positive regulation of cytokine production GO:0001819 174 0.011
regulation of mitotic cell cycle phase transition GO:1901990 73 0.011
regulation of metal ion transport GO:0010959 106 0.011
cellular response to peptide GO:1901653 92 0.011
habituation GO:0046959 3 0.011
regulation of leukocyte differentiation GO:1902105 159 0.010
plasma membrane organization GO:0007009 90 0.010
lymphocyte mediated immunity GO:0002449 139 0.010
neuromuscular process controlling balance GO:0050885 59 0.010
negative regulation of hormone biosynthetic process GO:0032353 4 0.010
regulation of cell cycle phase transition GO:1901987 77 0.010
histone methylation GO:0016571 71 0.010
negative regulation of protein maturation GO:1903318 79 0.010
meiotic nuclear division GO:0007126 115 0.010
defense response to other organism GO:0098542 197 0.010
synaptic vesicle localization GO:0097479 59 0.010
regulation of blood vessel size GO:0050880 56 0.010
innate immune response GO:0045087 157 0.010
regulation of lymphocyte differentiation GO:0045619 107 0.010
cellular response to insulin stimulus GO:0032869 78 0.010
negative regulation of neuron differentiation GO:0045665 101 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
response to inorganic substance GO:0010035 96 0.010
mapk cascade GO:0000165 281 0.010
bone morphogenesis GO:0060349 78 0.010
negative regulation of organic acid transport GO:0032891 1 0.010
posttranscriptional regulation of gene expression GO:0010608 155 0.010

Gabbr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.043
disease of cellular proliferation DOID:14566 0 0.016
central nervous system disease DOID:331 0 0.011
brain disease DOID:936 0 0.011