Mus musculus

290 known processes

Gata4

GATA binding protein 4

(Aliases: Gata-4)

Gata4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gene looping GO:0090202 2 1.000
Mouse
heart valve development GO:0003170 23 1.000
mitral valve morphogenesis GO:0003183 4 1.000
septum primum development GO:0003284 4 1.000
megakaryocyte differentiation GO:0030219 26 1.000
Mouse
regulation of cardioblast differentiation GO:0051890 3 1.000
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 1.000
positive regulation of cardioblast differentiation GO:0051891 3 1.000
atrioventricular valve formation GO:0003190 5 1.000
aortic valve morphogenesis GO:0003180 4 1.000
Mouse
mitral valve development GO:0003174 4 1.000
mesenchyme development GO:0060485 152 1.000
cardiac muscle tissue development GO:0048738 130 1.000
cardiac cell fate determination GO:0060913 2 1.000
Fly
epithelial tube morphogenesis GO:0060562 303 1.000
heart morphogenesis GO:0003007 178 1.000
embryonic heart tube anterior posterior pattern specification GO:0035054 3 1.000
embryonic heart tube development GO:0035050 65 1.000
regionalization GO:0003002 337 1.000
regulation of cardiac muscle tissue development GO:0055024 31 1.000
regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation GO:2000702 1 1.000
Mouse
glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000701 1 1.000
Mouse
heart valve morphogenesis GO:0003179 21 1.000
heart trabecula formation GO:0060347 14 1.000
cardiac septum development GO:0003279 59 0.999
erythrocyte differentiation GO:0030218 88 0.999
Mouse
striated muscle cell proliferation GO:0014855 39 0.999
embryonic heart tube morphogenesis GO:0003143 51 0.999
cardiac muscle tissue morphogenesis GO:0055008 44 0.999
Zebrafish
transcriptional activation by promoter enhancer looping GO:0071733 2 0.999
Mouse
stem cell differentiation GO:0048863 268 0.999
cardiocyte differentiation GO:0035051 87 0.999
heart valve formation GO:0003188 10 0.999
embryonic heart tube left right pattern formation GO:0060971 5 0.999
striated muscle tissue development GO:0014706 293 0.999
atrial cardiac muscle cell differentiation GO:0055011 2 0.999
atrial septum development GO:0003283 12 0.999
endocardial cushion morphogenesis GO:0003203 18 0.999
definitive erythrocyte differentiation GO:0060318 7 0.999
Mouse
negative regulation of glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000734 1 0.999
Mouse
regulation of glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000733 1 0.999
Mouse
cell migration involved in heart formation GO:0060974 1 0.999
Zebrafish
endocardial cushion to mesenchymal transition GO:0090500 5 0.999
lung lobe formation GO:0060464 1 0.999
cardiac chamber morphogenesis GO:0003206 93 0.999
regulation of peptide secretion GO:0002791 77 0.999
heart formation GO:0060914 16 0.999
Zebrafish
cardiac epithelial to mesenchymal transition GO:0060317 18 0.999
epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198 10 0.999
heart growth GO:0060419 45 0.998
cardiac septum morphogenesis GO:0060411 46 0.998
positive regulation of ureteric bud formation GO:0072107 3 0.998
Mouse
blood vessel morphogenesis GO:0048514 285 0.998
tricuspid valve development GO:0003175 3 0.998
atrioventricular valve morphogenesis GO:0003181 13 0.998
ventricular septum morphogenesis GO:0060412 27 0.998
atrial septum primum morphogenesis GO:0003289 3 0.998
positive regulation of heart growth GO:0060421 18 0.998
kidney development GO:0001822 213 0.997
Mouse
regulation of erythrocyte differentiation GO:0045646 23 0.997
Mouse
notochord formation GO:0014028 5 0.997
regulation of mast cell differentiation GO:0060375 3 0.997
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.997
Mouse
negative regulation of macrophage differentiation GO:0045650 4 0.997
Mouse
atrial cardiac muscle cell development GO:0055014 2 0.997
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.996
endocrine system development GO:0035270 98 0.996
Mouse
cardiac chamber development GO:0003205 108 0.996
regulation of histone h3 k4 methylation GO:0051569 12 0.996
Mouse
gabaergic neuron differentiation GO:0097154 11 0.996
Mouse
cardiac atrium development GO:0003230 24 0.996
neuron projection guidance GO:0097485 141 0.996
Mouse
ventricular septum development GO:0003281 42 0.996
cell fate commitment GO:0045165 210 0.996
positive regulation of transcription via serum response element binding GO:0010735 1 0.995
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.995
atrial septum morphogenesis GO:0060413 11 0.995
ventricular trabecula myocardium morphogenesis GO:0003222 11 0.995
organ growth GO:0035265 117 0.995
ventricular cardiac muscle cell differentiation GO:0055012 17 0.995
ascending aorta development GO:0035905 3 0.995
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.995
regulation of cardiac muscle tissue growth GO:0055021 26 0.994
regulation of forebrain neuron differentiation GO:2000977 2 0.994
Mouse
regulation of ureteric bud formation GO:0072106 3 0.994
Mouse
skeletal muscle cell differentiation GO:0035914 66 0.994
outflow tract morphogenesis GO:0003151 53 0.994
regulation of muscle tissue development GO:1901861 97 0.994
determination of left right symmetry GO:0007368 80 0.993
positive regulation of transcription regulatory region dna binding GO:2000679 1 0.993
Mouse
regulation of peptide hormone secretion GO:0090276 75 0.993
muscle tissue development GO:0060537 308 0.993
ventricular cardiac myofibril assembly GO:0055005 3 0.993
mesenchymal cell differentiation GO:0048762 107 0.993
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.992
regulation of definitive erythrocyte differentiation GO:0010724 3 0.992
Mouse
left right pattern formation GO:0060972 23 0.992
muscle tissue morphogenesis GO:0060415 53 0.992
Zebrafish
stem cell development GO:0048864 219 0.992
Mouse
cell migration involved in heart development GO:0060973 8 0.992
Zebrafish
epithelial cell fate commitment GO:0072148 13 0.992
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.992
vascular smooth muscle cell differentiation GO:0035886 11 0.992
regulation of cardiac muscle cell proliferation GO:0060043 23 0.992
embryonic skeletal system development GO:0048706 120 0.992
determination of heart left right asymmetry GO:0061371 48 0.991
tricuspid valve formation GO:0003195 2 0.991
nephron tubule epithelial cell differentiation GO:0072160 11 0.991
Mouse
response to bmp GO:0071772 14 0.991
Mouse
gland development GO:0048732 330 0.991
Zebrafish Mouse Fly
cardiac atrium morphogenesis GO:0003209 23 0.990
clara cell differentiation GO:0060486 4 0.990
Mouse
cardiac muscle adaptation GO:0014887 10 0.990
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.990
mast cell differentiation GO:0060374 5 0.990
Mouse
cardiac muscle cell differentiation GO:0055007 69 0.990
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.990
Zebrafish
activation of mapk activity involved in innate immune response GO:0035419 2 0.990
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.989
Mouse
embryonic placenta development GO:0001892 98 0.989
Mouse
hepaticobiliary system development GO:0061008 67 0.989
Zebrafish Mouse
endodermal cell fate specification GO:0001714 4 0.989
atrioventricular valve development GO:0003171 15 0.989
ventricular cardiac muscle cell development GO:0055015 11 0.989
muscle hypertrophy GO:0014896 24 0.989
regulation of heart growth GO:0060420 31 0.989
forebrain neuron fate commitment GO:0021877 13 0.989
Mouse
cardiac ventricle morphogenesis GO:0003208 50 0.988
cardiac muscle cell proliferation GO:0060038 31 0.988
cell fate determination GO:0001709 32 0.988
Mouse Fly
positive regulation of cardiac muscle tissue development GO:0055025 19 0.988
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.987
lens morphogenesis in camera type eye GO:0002089 24 0.987
telencephalon development GO:0021537 186 0.986
endocardial cushion development GO:0003197 26 0.986
embryonic organ morphogenesis GO:0048562 276 0.986
camera type eye development GO:0043010 266 0.986
Mouse
endocardial cushion formation GO:0003272 13 0.986
endocardial cell differentiation GO:0060956 4 0.985
nephron epithelium development GO:0072009 92 0.985
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.985
Mouse
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.985
epidermis development GO:0008544 187 0.985
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.985
cell proliferation involved in heart valve development GO:2000793 2 0.984
mesoderm morphogenesis GO:0048332 64 0.984
forebrain neuron differentiation GO:0021879 52 0.984
Mouse
hormone secretion GO:0046879 128 0.984
Mouse
positive regulation of male gonad development GO:2000020 6 0.984
platelet morphogenesis GO:0036344 13 0.984
Mouse
heart field specification GO:0003128 6 0.983
bmp signaling pathway GO:0030509 93 0.983
formation of primary germ layer GO:0001704 77 0.983
negative regulation of myeloid cell differentiation GO:0045638 38 0.982
Mouse
leukocyte differentiation GO:0002521 342 0.981
Mouse
pyramidal neuron migration GO:0021852 1 0.981
pulmonary valve development GO:0003177 5 0.981
renal vesicle development GO:0072087 17 0.981
coronary vasculature development GO:0060976 12 0.980
regulation of auditory receptor cell differentiation GO:0045607 4 0.980
endodermal cell fate commitment GO:0001711 12 0.980
Mouse
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.980
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.979
positive regulation of striated muscle tissue development GO:0045844 31 0.979
epithelial tube formation GO:0072175 130 0.977
Mouse
gastrulation GO:0007369 116 0.977
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.977
liver development GO:0001889 66 0.977
Zebrafish Mouse
pancreatic pp cell differentiation GO:0003312 2 0.977
mesenchyme morphogenesis GO:0072132 32 0.976
endoderm development GO:0007492 45 0.976
respiratory system development GO:0060541 190 0.976
myeloid cell differentiation GO:0030099 233 0.976
Zebrafish Mouse
t cell activation GO:0042110 289 0.976
Mouse
embryonic epithelial tube formation GO:0001838 130 0.973
Mouse
peptide hormone secretion GO:0030072 109 0.972
endoderm formation GO:0001706 20 0.972
lung development GO:0030324 164 0.972
cardiac endothelial cell differentiation GO:0003348 4 0.972
ventricular cardiac muscle tissue development GO:0003229 38 0.971
visceral serous pericardium development GO:0061032 2 0.971
myeloid cell homeostasis GO:0002262 114 0.971
Mouse
regulation of heart contraction GO:0008016 77 0.971
mesoderm formation GO:0001707 62 0.970
cellular amino acid metabolic process GO:0006520 103 0.970
regulation of organ growth GO:0046620 61 0.969
cell cell signaling involved in kidney development GO:0060995 2 0.968
Mouse
mesenchymal cell development GO:0014031 93 0.968
muscle cell proliferation GO:0033002 52 0.967
regulation of heart morphogenesis GO:2000826 22 0.967
gastrulation with mouth forming second GO:0001702 29 0.967
cardiac muscle cell development GO:0055013 39 0.966
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.966
wnt signaling pathway involved in kidney development GO:0061289 2 0.966
Mouse
tissue migration GO:0090130 68 0.966
closure of optic fissure GO:0061386 2 0.966
regulation of male gonad development GO:2000018 7 0.966
tendon cell differentiation GO:0035990 4 0.965
embryonic hemopoiesis GO:0035162 23 0.965
Mouse
cardiac right ventricle morphogenesis GO:0003215 13 0.965
aortic valve development GO:0003176 5 0.965
Mouse
positive regulation of megakaryocyte differentiation GO:0045654 4 0.964
Mouse
segmentation GO:0035282 93 0.964
Fly
regulation of binding GO:0051098 111 0.962
Mouse
phenol containing compound biosynthetic process GO:0046189 21 0.962
Mouse
cellular response to bmp stimulus GO:0071773 14 0.961
Mouse
secondary heart field specification GO:0003139 6 0.961
septum transversum development GO:0003343 2 0.960
digestive tract morphogenesis GO:0048546 147 0.960
cardioblast migration to the midline involved in heart field formation GO:0060975 1 0.959
Zebrafish
proepicardium development GO:0003342 2 0.958
neuron fate determination GO:0048664 9 0.958
kidney epithelium development GO:0072073 121 0.958
Mouse
atrioventricular canal development GO:0036302 5 0.956
muscular septum morphogenesis GO:0003150 4 0.955
hematopoietic progenitor cell differentiation GO:0002244 143 0.955
Mouse
antigen receptor mediated signaling pathway GO:0050851 64 0.955
Mouse
axon guidance GO:0007411 141 0.954
Mouse
lens development in camera type eye GO:0002088 62 0.954
Mouse
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.953
Mouse
tendon formation GO:0035992 4 0.953
histone methylation GO:0016571 71 0.953
Mouse
gonad development GO:0008406 141 0.953
regulation of bmp signaling pathway GO:0030510 60 0.953
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.951
positive regulation of erythrocyte differentiation GO:0045648 11 0.951
Mouse
insulin secretion GO:0030073 89 0.950
regulation of mesenchymal cell proliferation GO:0010464 37 0.950
development of primary male sexual characteristics GO:0046546 88 0.950
outflow tract septum morphogenesis GO:0003148 11 0.949
positive regulation of muscle tissue development GO:1901863 32 0.949
chondrocyte differentiation GO:0002062 72 0.948
nephron tubule development GO:0072080 84 0.946
Mouse
axonogenesis GO:0007409 274 0.945
Mouse
male gonad development GO:0008584 88 0.945
regulation of cellular amino acid metabolic process GO:0006521 5 0.945
positive regulation of t cell differentiation GO:0045582 52 0.945
Mouse
pigment metabolic process GO:0042440 32 0.944
Fly
cardiac pacemaker cell fate commitment GO:0060927 1 0.944
atrioventricular node cell development GO:0060928 2 0.944
regulation of transcription regulatory region dna binding GO:2000677 9 0.943
Mouse
renal system development GO:0072001 225 0.943
Mouse Fly
cellular response to gonadotropin stimulus GO:0071371 4 0.943
homeostasis of number of cells GO:0048872 210 0.943
Mouse
neural crest cell development GO:0014032 48 0.942
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.941
bundle of his development GO:0003166 4 0.941
embryonic heart tube formation GO:0003144 1 0.939
epithelial cell differentiation involved in kidney development GO:0035850 23 0.939
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.938
Mouse
neural crest cell migration GO:0001755 32 0.938
cardiac right ventricle formation GO:0003219 3 0.938
amine metabolic process GO:0009308 45 0.938
circulatory system process GO:0003013 197 0.938
Fly
foregut morphogenesis GO:0007440 12 0.937
mesonephric tubule development GO:0072164 94 0.937
Mouse
lung cell differentiation GO:0060479 30 0.936
Mouse
skeletal system morphogenesis GO:0048705 203 0.935
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.935
negative regulation of cell proliferation involved in mesonephros development GO:2000607 1 0.934
Mouse
cardioblast differentiation GO:0010002 13 0.931
negative regulation of mesodermal cell fate specification GO:0042662 3 0.930
t cell differentiation in thymus GO:0033077 77 0.930
Mouse
somite rostral caudal axis specification GO:0032525 13 0.929
somitogenesis GO:0001756 69 0.929
negative regulation of dna binding GO:0043392 20 0.927
cardiac ventricle development GO:0003231 83 0.926
forebrain development GO:0030900 302 0.925
Mouse
cardiac muscle tissue growth GO:0055017 37 0.925
cardiac ventricle formation GO:0003211 8 0.924
cardiac cell fate commitment GO:0060911 10 0.924
Fly
renal tubule morphogenesis GO:0061333 72 0.924
Mouse
blood circulation GO:0008015 195 0.924
Fly
astrocyte fate commitment GO:0060018 4 0.923
spinal cord development GO:0021510 81 0.923
Mouse
carbon catabolite activation of transcription GO:0045991 4 0.923
peptidyl amino acid modification GO:0018193 336 0.922
Mouse
placenta development GO:0001890 140 0.922
Mouse
tricuspid valve morphogenesis GO:0003186 2 0.922
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.922
ossification GO:0001503 216 0.921
Mouse
mesonephros development GO:0001823 97 0.920
Mouse
regulation of cytokine production GO:0001817 266 0.920
metanephric mesenchyme morphogenesis GO:0072133 4 0.919
pulmonary valve morphogenesis GO:0003184 5 0.919
response to fibroblast growth factor GO:0071774 47 0.919
Mouse
neural tube development GO:0021915 160 0.919
pancreatic a cell fate commitment GO:0003326 2 0.919
digestive system development GO:0055123 200 0.918
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.917
coagulation GO:0050817 78 0.916
Mouse
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.915
t cell receptor signaling pathway GO:0050852 46 0.915
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.915
tube formation GO:0035148 140 0.914
Mouse
pancreatic pp cell fate commitment GO:0003329 2 0.914
regulation of peptidyl lysine acetylation GO:2000756 22 0.913
Mouse
epithelial cell proliferation GO:0050673 174 0.912
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.912
comma shaped body morphogenesis GO:0072049 5 0.910
positive regulation of cellular amine metabolic process GO:0033240 5 0.910
regulation of neuron differentiation GO:0045664 281 0.909
Mouse
regulation of cardiac cell fate specification GO:2000043 1 0.909
ureteric bud morphogenesis GO:0060675 62 0.909
Mouse
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.909
norepinephrine biosynthetic process GO:0042421 5 0.909
Mouse
neural crest cell differentiation GO:0014033 54 0.908
nephron tubule morphogenesis GO:0072078 68 0.908
Mouse
his purkinje system cell differentiation GO:0060932 2 0.908
establishment or maintenance of cell polarity GO:0007163 86 0.908
Mouse
regulation of reproductive process GO:2000241 66 0.908
positive regulation of osteoblast proliferation GO:0033690 9 0.907
Mouse
positive regulation of epithelial cell proliferation GO:0050679 68 0.906
sinoatrial node cell differentiation GO:0060921 3 0.905
mesonephric tubule morphogenesis GO:0072171 63 0.903
Mouse
biological phase GO:0044848 20 0.903
regulation of osteoblast differentiation GO:0045667 67 0.901
lung epithelial cell differentiation GO:0060487 29 0.898
Mouse
heart process GO:0003015 94 0.898
Fly
t helper 2 cell differentiation GO:0045064 12 0.897
Mouse
positive regulation of transcription by glucose GO:0046016 3 0.893
central nervous system neuron differentiation GO:0021953 162 0.892
Mouse
endodermal cell fate determination GO:0007493 2 0.892
Mouse
skeletal muscle organ development GO:0060538 163 0.891
primary prostatic bud elongation GO:0060516 2 0.889
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.889
cellular amide metabolic process GO:0043603 58 0.888
Fly
pituitary gland development GO:0021983 38 0.887
Mouse
trophoblast giant cell differentiation GO:0060707 15 0.887
purkinje myocyte differentiation GO:0003168 1 0.887
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.886
heart trabecula morphogenesis GO:0061384 26 0.885
regulation of glial cell differentiation GO:0045685 41 0.885
regulation of antimicrobial humoral response GO:0002759 3 0.884
Fly
response to follicle stimulating hormone GO:0032354 1 0.884
embryonic viscerocranium morphogenesis GO:0048703 8 0.882
sertoli cell differentiation GO:0060008 18 0.882
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.882
somite development GO:0061053 81 0.882
cell type specific apoptotic process GO:0097285 268 0.880
Mouse
hemangioblast cell differentiation GO:0060217 1 0.878
muscle hypertrophy in response to stress GO:0003299 10 0.877
regulation of wnt signaling pathway GO:0030111 123 0.877
cell proliferation involved in kidney development GO:0072111 14 0.876
Mouse
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.873
regulation of gastrulation GO:0010470 16 0.873
regulation of cellular ketone metabolic process GO:0010565 66 0.873
activation of immune response GO:0002253 138 0.873
Mouse
positive regulation of bmp signaling pathway GO:0030513 23 0.872
regulation of cartilage development GO:0061035 44 0.872
auditory receptor cell fate determination GO:0042668 3 0.870
epithelial to mesenchymal transition GO:0001837 47 0.870
regulation of epithelial cell proliferation GO:0050678 141 0.869
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.868
primitive streak formation GO:0090009 10 0.867
ventral spinal cord interneuron fate determination GO:0060580 1 0.865
peptide secretion GO:0002790 114 0.865
atrioventricular node cell differentiation GO:0060922 2 0.864
collagen fibril organization GO:0030199 32 0.863
cell cell signaling involved in metanephros development GO:0072204 2 0.860
Mouse
bone development GO:0060348 120 0.856
regulation of endodermal cell differentiation GO:1903224 2 0.854
stem cell proliferation GO:0072089 117 0.854
heart contraction GO:0060047 93 0.854
Fly
cardiac cell development GO:0055006 41 0.852
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.852
kidney mesenchyme morphogenesis GO:0072131 4 0.852
regulation of epidermal cell differentiation GO:0045604 21 0.852
neural precursor cell proliferation GO:0061351 121 0.851
Mouse
regulation of cell proliferation involved in heart morphogenesis GO:2000136 15 0.850
cellular response to growth factor stimulus GO:0071363 197 0.849
Mouse
cardiac conduction system development GO:0003161 12 0.849
regulation of transcription involved in cell fate commitment GO:0060850 15 0.848
atrioventricular node development GO:0003162 3 0.840
negative regulation of neuron differentiation GO:0045665 101 0.837
mesodermal cell migration GO:0008078 4 0.837
autonomic nervous system development GO:0048483 43 0.836
Mouse
anterior commissure morphogenesis GO:0021960 6 0.836
cardioblast migration GO:0003260 1 0.835
Zebrafish
multicellular organism growth GO:0035264 161 0.834
cellular amine metabolic process GO:0044106 44 0.833
coronary vasculature morphogenesis GO:0060977 9 0.833
regulation of organ morphogenesis GO:2000027 144 0.830
Mouse
glial cell derived neurotrophic factor receptor signaling pathway GO:0035860 3 0.830
Mouse
endothelium development GO:0003158 45 0.830
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.829
single organismal cell cell adhesion GO:0016337 131 0.829
Mouse
antimicrobial peptide production GO:0002775 2 0.829
Fly
pancreas development GO:0031016 57 0.828
Mouse
auditory receptor cell fate specification GO:0042667 1 0.828
protein methylation GO:0006479 81 0.828
Mouse
regulation of hormone secretion GO:0046883 88 0.827
chromatin modification GO:0016568 187 0.826
Mouse
renal tubule development GO:0061326 87 0.823
Mouse
regulation of cell proliferation involved in mesonephros development GO:2000606 1 0.823
Mouse
cell migration involved in gastrulation GO:0042074 13 0.822
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.821
positive regulation of growth GO:0045927 104 0.817
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.817
Mouse
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.816
Mouse
cell proliferation involved in mesonephros development GO:0061209 4 0.814
Mouse
histone acetylation GO:0016573 41 0.814
Mouse
development of primary female sexual characteristics GO:0046545 73 0.813
lymphocyte differentiation GO:0030098 242 0.811
Mouse
cellular response to oxygen levels GO:0071453 20 0.810
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.810
Mouse
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.810
regulation of endodermal cell fate specification GO:0042663 2 0.808
cell adhesion GO:0007155 329 0.806
Mouse
pallium development GO:0021543 120 0.805
transforming growth factor beta2 production GO:0032906 2 0.805
amide transport GO:0042886 138 0.805
urogenital system development GO:0001655 261 0.804
Mouse Fly
megakaryocyte development GO:0035855 15 0.803
negative regulation of gastrulation GO:2000542 3 0.801
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.799
Human Mouse
nephron morphogenesis GO:0072028 69 0.799
Mouse
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.798
Mouse
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.797
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.796
cytokine production GO:0001816 319 0.795
ear morphogenesis GO:0042471 118 0.794
Mouse
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.788
atrioventricular node cell fate commitment GO:0060929 1 0.787
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.785
Mouse
endothelial cell differentiation GO:0045446 41 0.784
regulation of antimicrobial peptide production GO:0002784 1 0.783
Fly
regulation of transforming growth factor beta2 production GO:0032909 2 0.781
branching morphogenesis of an epithelial tube GO:0048754 159 0.781
t cell differentiation GO:0030217 174 0.780
Mouse
dna metabolic process GO:0006259 303 0.780
regulation of epithelial to mesenchymal transition GO:0010717 22 0.779
cell differentiation in spinal cord GO:0021515 53 0.778
Mouse
spinal cord motor neuron migration GO:0097476 4 0.776
male sex differentiation GO:0046661 109 0.775
positive regulation of osteoblast differentiation GO:0045669 34 0.774
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.774
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.772
positive regulation of reproductive process GO:2000243 19 0.770
endocardium development GO:0003157 10 0.770
regulation of vasculature development GO:1901342 88 0.770
regulation of chromatin modification GO:1903308 57 0.769
Mouse
regulation of angiogenesis GO:0045765 81 0.768
dsdna loop formation GO:0090579 2 0.767
Mouse
lung morphogenesis GO:0060425 50 0.766
nephron epithelium morphogenesis GO:0072088 68 0.763
Mouse
peptide biosynthetic process GO:0043043 11 0.762
Fly
positive regulation of cardiac muscle cell differentiation GO:2000727 6 0.761
retinal ganglion cell axon guidance GO:0031290 18 0.761
t cell selection GO:0045058 34 0.759
Mouse
embryonic axis specification GO:0000578 30 0.759
negative regulation of defense response GO:0031348 77 0.758
regulation of cardiac muscle contraction GO:0055117 21 0.757
protein acylation GO:0043543 64 0.756
Mouse
cardiac muscle fiber development GO:0048739 4 0.753
alpha beta t cell differentiation GO:0046632 69 0.751
Mouse
regulation of blood circulation GO:1903522 93 0.749
protein alkylation GO:0008213 81 0.747
Mouse
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.747
regulation of myeloid leukocyte differentiation GO:0002761 58 0.746
Mouse
hypothalamus cell migration GO:0021855 5 0.743
cerebral cortex cell migration GO:0021795 44 0.742
immune response regulating signaling pathway GO:0002764 125 0.742
Mouse
mesendoderm development GO:0048382 3 0.741
artery development GO:0060840 53 0.741
regulation of embryonic development GO:0045995 71 0.741
Mouse
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.741
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.741
positive regulation of cell proliferation involved in heart valve morphogenesis GO:0003251 1 0.741
negative regulation of cell cycle GO:0045786 123 0.739
Mouse
negative regulation of neuron projection development GO:0010977 50 0.739
regulation of chondrocyte differentiation GO:0032330 33 0.738
keratinocyte proliferation GO:0043616 21 0.738
septum secundum development GO:0003285 1 0.736
Human
auditory receptor cell differentiation GO:0042491 37 0.736
neural tube closure GO:0001843 90 0.734
extracellular matrix dependent thymocyte migration GO:0072680 1 0.734
cell cycle arrest GO:0007050 37 0.730
lateral motor column neuron migration GO:0097477 3 0.730
nephrogenic mesenchyme development GO:0072076 3 0.730
cardiac neural crest cell development involved in heart development GO:0061308 7 0.728
epithelial cell development GO:0002064 159 0.728
bone morphogenesis GO:0060349 78 0.728
blastocyst formation GO:0001825 33 0.727
diencephalon development GO:0021536 63 0.727
Mouse
lung induction GO:0060492 3 0.727
labyrinthine layer development GO:0060711 49 0.726
blastoderm segmentation GO:0007350 13 0.724
Fly
skeletal system development GO:0001501 356 0.722
digestive tract development GO:0048565 190 0.722
platelet aggregation GO:0070527 20 0.721
Mouse

Gata4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 0 1.000
Human
disease of anatomical entity DOID:7 0 1.000
Human
cardiovascular system disease DOID:1287 0 1.000
Human
congenital heart disease DOID:1682 0 1.000
Human
heart septal defect DOID:1681 0 1.000
Human
ventricular septal defect DOID:1657 0 1.000
Human
tetralogy of fallot DOID:6419 0 0.999
Human
atrioventricular septal defect DOID:0050651 0 0.741
Human