|
|
pyroptosis
|
GO:0070269 |
8 |
0.998
|
|
|
|
positive regulation of interleukin 1 secretion
|
GO:0050716 |
14 |
0.993
|
|
|
|
positive regulation of interleukin 1 alpha secretion
|
GO:0050717 |
3 |
0.991
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
23 |
0.985
|
|
|
|
negative regulation of necrotic cell death
|
GO:0060547 |
11 |
0.983
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
16 |
0.950
|
|
|
|
positive regulation of interleukin 1 beta production
|
GO:0032731 |
16 |
0.946
|
|
|
|
regulation of interleukin 1 alpha production
|
GO:0032650 |
4 |
0.934
|
|
|
|
negative regulation of necroptotic process
|
GO:0060546 |
9 |
0.931
|
|
|
|
interleukin 1 secretion
|
GO:0050701 |
16 |
0.930
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
25 |
0.918
|
|
|
|
regulation of interleukin 1 secretion
|
GO:0050704 |
15 |
0.912
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.876
|
|
|
|
regulation of apoptotic dna fragmentation
|
GO:1902510 |
5 |
0.875
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001267 |
4 |
0.869
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.841
|
|
|
|
positive regulation of interleukin 1 beta secretion
|
GO:0050718 |
14 |
0.839
|
|
|
|
dna catabolic process endonucleolytic
|
GO:0000737 |
15 |
0.831
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.829
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.829
|
|
|
|
positive regulation of release of cytochrome c from mitochondria
|
GO:0090200 |
5 |
0.826
|
|
|
|
interleukin 1 alpha secretion
|
GO:0050703 |
3 |
0.814
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.814
|
|
|
|
regulation of execution phase of apoptosis
|
GO:1900117 |
9 |
0.802
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.799
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
30 |
0.797
|
|
|
|
sperm individualization
|
GO:0007291 |
1 |
0.788
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001269 |
3 |
0.785
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.780
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.769
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.769
|
|
|
|
regulation of interleukin 1 beta secretion
|
GO:0050706 |
15 |
0.767
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.752
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
19 |
0.750
|
|
|
|
circadian sleep wake cycle non rem sleep
|
GO:0042748 |
2 |
0.748
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
8 |
0.743
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.736
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.728
|
|
|
|
regulation of interleukin 1 alpha secretion
|
GO:0050705 |
3 |
0.719
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.718
|
|
|
|
regulation of necroptotic process
|
GO:0060544 |
10 |
0.713
|
|
|
|
positive regulation of interleukin 1 alpha production
|
GO:0032730 |
4 |
0.698
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.681
|
Mouse |
|
|
membrane hyperpolarization
|
GO:0060081 |
21 |
0.676
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.666
|
|
|
|
apoptotic dna fragmentation
|
GO:0006309 |
7 |
0.666
|
|
|
|
positive regulation of interleukin 6 secretion
|
GO:2000778 |
1 |
0.660
|
|
|
|
regulation of activated t cell proliferation
|
GO:0046006 |
16 |
0.656
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.655
|
|
|
|
cellular component disassembly involved in execution phase of apoptosis
|
GO:0006921 |
9 |
0.633
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.621
|
Mouse |
|
|
negative regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045736 |
9 |
0.614
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.613
|
Mouse |
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.604
|
|
|
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.592
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.591
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.579
|
|
|
|
positive regulation of interleukin 8 secretion
|
GO:2000484 |
1 |
0.573
|
|
|
|
response to atp
|
GO:0033198 |
8 |
0.566
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.563
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.560
|
|
|
|
secondary metabolic process
|
GO:0019748 |
18 |
0.555
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.554
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.548
|
Mouse |
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.538
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.527
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.515
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.514
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.513
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.506
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.505
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.504
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.485
|
Mouse |
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.481
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.475
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.475
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.474
|
|
|
|
positive regulation of defense response to virus by host
|
GO:0002230 |
6 |
0.471
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.470
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.467
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.459
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.453
|
Mouse |
|
|
positive regulation of interleukin 1 production
|
GO:0032732 |
17 |
0.452
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
17 |
0.451
|
|
|
|
negative regulation of nik nf kappab signaling
|
GO:1901223 |
2 |
0.448
|
|
|
|
toxin transport
|
GO:1901998 |
38 |
0.448
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.443
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.443
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.442
|
Mouse |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.441
|
|
|
|
necroptotic process
|
GO:0070266 |
21 |
0.438
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.436
|
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.435
|
|
|
|
apoptotic nuclear changes
|
GO:0030262 |
9 |
0.432
|
|
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.432
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.432
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.419
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.419
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.410
|
Mouse |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.410
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.407
|
|
|
|
regulation of dna catabolic process
|
GO:1903624 |
5 |
0.406
|
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.400
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
2 |
0.399
|
|
|
|
response to topologically incorrect protein
|
GO:0035966 |
25 |
0.394
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.384
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.382
|
Mouse |
|
|
negative regulation of activated t cell proliferation
|
GO:0046007 |
7 |
0.379
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.379
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.378
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.369
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.364
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.358
|
|
|
|
myeloid dendritic cell activation involved in immune response
|
GO:0002277 |
2 |
0.357
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
33 |
0.354
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.354
|
|
|
|
positive regulation of interleukin 10 secretion
|
GO:2001181 |
1 |
0.352
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.351
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.350
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.350
|
Mouse |
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.349
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.348
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.347
|
|
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.347
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.345
|
|
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.344
|
|
|
|
mitochondrial depolarization
|
GO:0051882 |
6 |
0.342
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.332
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.330
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.329
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.328
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.325
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.324
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.322
|
Mouse |
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
13 |
0.321
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.316
|
Mouse |
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.313
|
|
|
|
interleukin 6 secretion
|
GO:0072604 |
3 |
0.310
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
13 |
0.310
|
|
|
|
thymocyte apoptotic process
|
GO:0070242 |
19 |
0.308
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.303
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.300
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.298
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.298
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.296
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.294
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.290
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.288
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.286
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.285
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.285
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.283
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.282
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.280
|
Mouse |
|
|
membrane organization
|
GO:0061024 |
245 |
0.273
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.264
|
|
|
|
positive regulation of chemokine secretion
|
GO:0090197 |
4 |
0.263
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.263
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.262
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
5 |
0.260
|
|
|
|
pigment metabolic process
|
GO:0042440 |
32 |
0.255
|
|
|
|
protein autoprocessing
|
GO:0016540 |
2 |
0.254
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
18 |
0.252
|
Mouse |
|
|
epidermis development
|
GO:0008544 |
187 |
0.252
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.250
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.248
|
Mouse |
|
|
er nucleus signaling pathway
|
GO:0006984 |
27 |
0.248
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.248
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.248
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.246
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.246
|
|
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
11 |
0.245
|
|
|
|
regulation of autophagy
|
GO:0010506 |
30 |
0.242
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.242
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.240
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.240
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.239
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.235
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.234
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.233
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.229
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.229
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.223
|
|
|
|
antigen processing and presentation of peptide antigen
|
GO:0048002 |
29 |
0.223
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.222
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.217
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
26 |
0.215
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.215
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.214
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.214
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.213
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.212
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
14 |
0.211
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.210
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.206
|
Mouse |
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.204
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.202
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.199
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.198
|
|
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.197
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.196
|
|
|
|
regulation of circadian sleep wake cycle non rem sleep
|
GO:0045188 |
1 |
0.193
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.191
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.190
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.189
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
16 |
0.186
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.186
|
|
|
|
response to interleukin 1
|
GO:0070555 |
11 |
0.184
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.179
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.177
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.176
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
27 |
0.176
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.175
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.174
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
39 |
0.174
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.173
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
3 |
0.173
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.172
|
|
|
|
regulation of chemokine secretion
|
GO:0090196 |
4 |
0.172
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.171
|
|
|
|
regulation of tumor necrosis factor mediated signaling pathway
|
GO:0010803 |
3 |
0.169
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.168
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.167
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.166
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.164
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.164
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.159
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.156
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.156
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.154
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.148
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.148
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.148
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.147
|
Mouse |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.145
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.145
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
2 |
0.144
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.143
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.140
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
49 |
0.139
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.137
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.135
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.133
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.132
|
Mouse |
|
|
negative regulation of interferon beta production
|
GO:0032688 |
3 |
0.131
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.130
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.128
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.128
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.127
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.127
|
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
60 |
0.126
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.125
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.125
|
|
|
|
neuron maturation
|
GO:0042551 |
29 |
0.124
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
21 |
0.124
|
|
|
|
rhythmic behavior
|
GO:0007622 |
15 |
0.124
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.123
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.121
|
|
|
|
response to organophosphorus
|
GO:0046683 |
22 |
0.121
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.120
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.119
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.118
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.117
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.117
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.117
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.116
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.114
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.113
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.113
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.112
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.110
|
|
|
|
hepatocyte apoptotic process
|
GO:0097284 |
11 |
0.109
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.108
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
11 |
0.107
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.107
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.106
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
25 |
0.106
|
|
|
|
dna catabolic process
|
GO:0006308 |
19 |
0.104
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.103
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.103
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.103
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.102
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.102
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.101
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.099
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.099
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.097
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.097
|
|
|
|
regulation of t cell apoptotic process
|
GO:0070232 |
28 |
0.097
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.095
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.095
|
Mouse |
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.094
|
|
|
|
response to purine containing compound
|
GO:0014074 |
28 |
0.094
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.093
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
24 |
0.093
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.092
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.091
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.091
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.091
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.090
|
Mouse |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.090
|
|
|
|
peptide biosynthetic process
|
GO:0043043 |
11 |
0.090
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.088
|
|
|
|
t cell homeostasis
|
GO:0043029 |
35 |
0.087
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.085
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.084
|
|
|
|
cellular response to corticosteroid stimulus
|
GO:0071384 |
13 |
0.084
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.083
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.083
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.080
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.080
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.080
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.080
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.079
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.079
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.079
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.078
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.078
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.077
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.076
|
|
|
|
melanin metabolic process
|
GO:0006582 |
12 |
0.075
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.074
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
19 |
0.074
|
|
|
|
ectopic germ cell programmed cell death
|
GO:0035234 |
9 |
0.073
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.070
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.069
|
|
|
|
macrophage activation
|
GO:0042116 |
27 |
0.069
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.068
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.067
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.067
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.067
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.067
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.066
|
|
|
|
response to unfolded protein
|
GO:0006986 |
21 |
0.066
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.065
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.064
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.064
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
0.064
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.064
|
|
|
|
response to dexamethasone
|
GO:0071548 |
8 |
0.062
|
|
|
|
response to ketone
|
GO:1901654 |
15 |
0.062
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.062
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.062
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.061
|
Mouse |
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.061
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.061
|
|
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
19 |
0.060
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.060
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.059
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.058
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.058
|
|
|
|
neuron remodeling
|
GO:0016322 |
7 |
0.058
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
25 |
0.058
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.057
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.055
|
Mouse |
|
|
regulation of rac protein signal transduction
|
GO:0035020 |
19 |
0.055
|
|
|
|
cellular response to ketone
|
GO:1901655 |
12 |
0.054
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.054
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
15 |
0.054
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.054
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
26 |
0.054
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.053
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.053
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.053
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.053
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.053
|
|
|
|
cellular response to dexamethasone stimulus
|
GO:0071549 |
8 |
0.053
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.053
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.053
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.051
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.051
|
|
|
|
cellular response to alcohol
|
GO:0097306 |
23 |
0.051
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
23 |
0.050
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.050
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.050
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
24 |
0.049
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.049
|
|
|
|
regulation of interleukin 18 production
|
GO:0032661 |
3 |
0.049
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.048
|
|
|
|
interleukin 8 secretion
|
GO:0072606 |
3 |
0.048
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.047
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.047
|
|
|
|
regulation of antibacterial peptide biosynthetic process
|
GO:0002808 |
1 |
0.047
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.047
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.047
|
|
|
|
phagocytosis engulfment
|
GO:0006911 |
16 |
0.046
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.046
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.046
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.046
|
|
|
|
regulation of necrotic cell death
|
GO:0010939 |
13 |
0.046
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.046
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.046
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.045
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.045
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.044
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.043
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.043
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.043
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
41 |
0.042
|
|
|
|
interferon beta production
|
GO:0032608 |
16 |
0.042
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.041
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.041
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.041
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.041
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.040
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.039
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.038
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.038
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.037
|
Mouse |
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.037
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.037
|
Mouse |
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.037
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.035
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.035
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.035
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.035
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.035
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.035
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.034
|
Mouse |
|
|
sleep
|
GO:0030431 |
7 |
0.034
|
|
|
|
macropinocytosis
|
GO:0044351 |
4 |
0.034
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.034
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.034
|
|
|
|
interleukin 1 alpha production
|
GO:0032610 |
5 |
0.033
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.032
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.032
|
|
|
|
positive regulation of interleukin 10 production
|
GO:0032733 |
12 |
0.032
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.032
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.032
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.032
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.032
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.032
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
27 |
0.031
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.031
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.031
|
Mouse |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.031
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.031
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.031
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.030
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.030
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.030
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
21 |
0.030
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.030
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.029
|
|
|
|
chemokine secretion
|
GO:0090195 |
5 |
0.029
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.029
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.029
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.029
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
26 |
0.029
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.029
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.029
|
|
|
|
pinocytosis
|
GO:0006907 |
6 |
0.028
|
|
|
|
interleukin 10 production
|
GO:0032613 |
23 |
0.028
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.028
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.028
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.028
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
8 |
0.027
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.027
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.027
|
Mouse |
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.027
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.026
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.026
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.026
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.026
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.026
|
|
|
|
apoptotic process involved in development
|
GO:1902742 |
28 |
0.026
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.026
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.026
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.026
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.025
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.025
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.025
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.025
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.025
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.025
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.024
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.024
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.024
|
|
|
|
chemokine production
|
GO:0032602 |
34 |
0.024
|
|
|
|
positive regulation of mitochondrion organization
|
GO:0010822 |
17 |
0.024
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.024
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.024
|
|
|
|
helper t cell enhancement of adaptive immune response
|
GO:0035397 |
1 |
0.024
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.024
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.024
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.024
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.024
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.024
|
|
|
|
regulation of thymocyte apoptotic process
|
GO:0070243 |
14 |
0.024
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.024
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.024
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.023
|
|
|
|
positive regulation of antibacterial peptide production
|
GO:0002803 |
1 |
0.023
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
21 |
0.022
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.022
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.022
|
|
