Mus musculus

107 known processes

Gck

glucokinase

(Aliases: HKIV,GLK,HK4,MODY2,HXKP,Gk)

Gck biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of secretion GO:0051046 274 0.611
cation transport GO:0006812 399 0.350
gland development GO:0048732 330 0.337
regulation of carbohydrate metabolic process GO:0006109 75 0.319
Human Rat
peptide secretion GO:0002790 114 0.301
cellular metal ion homeostasis GO:0006875 151 0.299
Rat
cellular chemical homeostasis GO:0055082 215 0.291
cellular amino acid metabolic process GO:0006520 103 0.281
glycoprotein metabolic process GO:0009100 116 0.278
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.258
Human Rat
organic acid biosynthetic process GO:0016053 86 0.256
carbohydrate homeostasis GO:0033500 128 0.251
positive regulation of hormone secretion GO:0046887 38 0.250
regulation of body fluid levels GO:0050878 162 0.248
glucose metabolic process GO:0006006 92 0.231
g protein coupled receptor signaling pathway GO:0007186 243 0.225
cytoplasmic transport GO:0016482 234 0.207
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.191
regulation of circadian sleep wake cycle GO:0042749 3 0.191
positive regulation of peptide hormone secretion GO:0090277 31 0.189
monocarboxylic acid metabolic process GO:0032787 191 0.186
Rat
positive regulation of cellular amine metabolic process GO:0033240 5 0.183
inflammatory response to wounding GO:0090594 4 0.182
cellular carbohydrate metabolic process GO:0044262 119 0.174
glucose homeostasis GO:0042593 128 0.169
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.169
positive regulation of peptide secretion GO:0002793 33 0.164
peptidyl amino acid modification GO:0018193 336 0.159
response to oxygen levels GO:0070482 62 0.154
cellular ion homeostasis GO:0006873 165 0.151
Rat
regulation of homeostatic process GO:0032844 182 0.149
regulation of kinase activity GO:0043549 249 0.144
regulation of secretion by cell GO:1903530 249 0.139
cellular calcium ion homeostasis GO:0006874 119 0.137
Rat
viral process GO:0016032 41 0.132
generation of precursor metabolites and energy GO:0006091 103 0.132
Human Rat
eye photoreceptor cell development GO:0042462 31 0.129
lipid biosynthetic process GO:0008610 179 0.127
intracellular protein transport GO:0006886 204 0.127
glycolytic process GO:0006096 20 0.125
Rat
regulation of peptide transport GO:0090087 91 0.124
hormone secretion GO:0046879 128 0.122
carbohydrate metabolic process GO:0005975 230 0.119
regulation of transferase activity GO:0051338 263 0.116
cilium morphogenesis GO:0060271 102 0.116
hypoxia inducible factor 1alpha signaling pathway GO:0097411 2 0.115
nuclear transport GO:0051169 139 0.110
carboxylic acid biosynthetic process GO:0046394 86 0.108
regulation of circadian rhythm GO:0042752 58 0.107
positive regulation of insulin secretion GO:0032024 26 0.103
fat soluble vitamin biosynthetic process GO:0042362 4 0.100
blood vessel remodeling GO:0001974 33 0.100
pyruvate metabolic process GO:0006090 28 0.100
Rat
monosaccharide metabolic process GO:0005996 106 0.099
insulin secretion GO:0030073 89 0.099
nitrogen compound transport GO:0071705 271 0.097
regulation of cellular amine metabolic process GO:0033238 20 0.096
cellular amine metabolic process GO:0044106 44 0.096
endocytosis GO:0006897 168 0.095
lactation GO:0007595 25 0.094
positive regulation of ion transport GO:0043270 65 0.094
protein import into nucleus translocation GO:0000060 12 0.093
response to decreased oxygen levels GO:0036293 59 0.092
lipid transport GO:0006869 98 0.089
protein localization to organelle GO:0033365 185 0.086
regulation of vesicle mediated transport GO:0060627 139 0.086
cellular ketone metabolic process GO:0042180 84 0.086
Human
cellular homeostasis GO:0019725 240 0.084
metal ion homeostasis GO:0055065 189 0.081
Rat
positive regulation of steroid hormone secretion GO:2000833 2 0.081
response to hypoxia GO:0001666 58 0.080
nucleotide metabolic process GO:0009117 332 0.080
regulation of peptide secretion GO:0002791 77 0.080
sequestering of calcium ion GO:0051208 18 0.079
single organism nuclear import GO:1902593 95 0.078
skin development GO:0043588 220 0.075
regulation of glucose metabolic process GO:0010906 60 0.075
Human
energy derivation by oxidation of organic compounds GO:0015980 77 0.075
Human Rat
asymmetric stem cell division GO:0098722 3 0.074
camera type eye development GO:0043010 266 0.074
body fluid secretion GO:0007589 53 0.073
response to light stimulus GO:0009416 135 0.073
hexose metabolic process GO:0019318 98 0.073
nucleocytoplasmic transport GO:0006913 139 0.073
cellular response to monosaccharide stimulus GO:0071326 47 0.072
negative regulation of growth GO:0045926 99 0.072
cellular response to organonitrogen compound GO:0071417 145 0.072
Rat
divalent inorganic cation homeostasis GO:0072507 138 0.070
Rat
response to organonitrogen compound GO:0010243 246 0.066
Rat
cellular divalent inorganic cation homeostasis GO:0072503 127 0.065
Rat
positive regulation of transferase activity GO:0051347 167 0.064
sequestering of metal ion GO:0051238 19 0.063
regulation of establishment of protein localization GO:0070201 181 0.063
cell type specific apoptotic process GO:0097285 268 0.063
t helper 2 cell cytokine production GO:0035745 4 0.063
protein import into nucleus GO:0006606 95 0.062
oxidation reduction process GO:0055114 342 0.062
Human Rat
positive regulation of kinase activity GO:0033674 155 0.062
peptide transport GO:0015833 133 0.060
anatomical structure homeostasis GO:0060249 145 0.060
protein targeting GO:0006605 143 0.060
regulation of protein localization GO:0032880 231 0.059
alpha amino acid metabolic process GO:1901605 59 0.059
interspecies interaction between organisms GO:0044419 83 0.058
calcium ion homeostasis GO:0055074 127 0.058
Rat
establishment of protein localization to organelle GO:0072594 118 0.058
muscle cell differentiation GO:0042692 261 0.057
photoreceptor cell differentiation GO:0046530 52 0.056
protein localization to nucleus GO:0034504 121 0.056
regulation of feeding behavior GO:0060259 3 0.056
regulation of cell motility GO:2000145 236 0.054
regulation of generation of precursor metabolites and energy GO:0043467 38 0.053
Human Rat
fatty acid metabolic process GO:0006631 121 0.052
regulation of cell migration GO:0030334 219 0.052
maintenance of location GO:0051235 89 0.052
cellular glucose homeostasis GO:0001678 52 0.051
negative regulation of kinase activity GO:0033673 81 0.050
regulation of protein transport GO:0051223 163 0.050
retinal cone cell development GO:0046549 8 0.050
organic hydroxy compound metabolic process GO:1901615 203 0.050
cellular response to peptide GO:1901653 92 0.050
Rat
negative regulation of molecular function GO:0044092 258 0.049
cellular response to insulin stimulus GO:0032869 78 0.048
Rat
negative regulation of immune system process GO:0002683 209 0.046
eye photoreceptor cell differentiation GO:0001754 41 0.046
regulation of glucan biosynthetic process GO:0010962 7 0.046
Human
regulation of anatomical structure size GO:0090066 178 0.046
response to organic cyclic compound GO:0014070 198 0.046
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.046
regulation of leukocyte apoptotic process GO:2000106 56 0.046
negative regulation of feeding behavior GO:2000252 1 0.045
visual learning GO:0008542 44 0.045
response to testosterone GO:0033574 3 0.045
response to monosaccharide GO:0034284 67 0.045
Human Rat
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.045
regulation of carbohydrate biosynthetic process GO:0043255 40 0.044
Human
purine nucleoside metabolic process GO:0042278 241 0.044
regulation of neuron apoptotic process GO:0043523 122 0.044
negative regulation of phosphate metabolic process GO:0045936 184 0.044
positive regulation of homeostatic process GO:0032846 64 0.043
negative regulation of phosphorylation GO:0042326 166 0.043
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.042
response to oxidative stress GO:0006979 123 0.042
lipid catabolic process GO:0016042 69 0.042
regulation of ion transport GO:0043269 215 0.042
tyrosine phosphorylation of stat protein GO:0007260 23 0.042
positive regulation of glucose metabolic process GO:0010907 21 0.042
Human
naphthalene metabolic process GO:0018931 1 0.041
t cell activation GO:0042110 289 0.041
regulation of cellular catabolic process GO:0031329 242 0.041
Rat
protein import GO:0017038 101 0.041
positive regulation of secretion by cell GO:1903532 114 0.041
regulation of tor signaling GO:0032006 17 0.041
cellular response to dna damage stimulus GO:0006974 207 0.041
neuron apoptotic process GO:0051402 142 0.040
placenta development GO:0001890 140 0.039
neuron death GO:0070997 154 0.039
mitochondrion organization GO:0007005 134 0.039
Mouse
photoreceptor cell development GO:0042461 40 0.039
ribonucleotide metabolic process GO:0009259 291 0.038
purine nucleotide metabolic process GO:0006163 302 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.038
Human
response to peptide hormone GO:0043434 127 0.038
Rat
cytokine production GO:0001816 319 0.038
regulation of lymphocyte activation GO:0051249 240 0.038
regulation of neuron death GO:1901214 134 0.037
negative regulation of cellular carbohydrate metabolic process GO:0010677 19 0.037
Human
protein heterotetramerization GO:0051290 4 0.037
ras protein signal transduction GO:0007265 77 0.037
regulation of leukocyte differentiation GO:1902105 159 0.036
reactive oxygen species biosynthetic process GO:1903409 8 0.036
regulation of cell cycle GO:0051726 281 0.036
catecholamine metabolic process GO:0006584 30 0.036
negative regulation of hexokinase activity GO:1903300 4 0.036
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.035
leukocyte apoptotic process GO:0071887 71 0.035
regulation of glycolytic process GO:0006110 10 0.035
Rat
cation homeostasis GO:0055080 212 0.035
Rat
regulation of cytoplasmic transport GO:1903649 112 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
tissue remodeling GO:0048771 102 0.034
norepinephrine secretion GO:0048243 2 0.034
sensory perception GO:0007600 245 0.034
chemotaxis GO:0006935 247 0.034
extrinsic apoptotic signaling pathway GO:0097191 126 0.034
positive regulation of protein kinase activity GO:0045860 144 0.033
reactive nitrogen species metabolic process GO:2001057 0 0.033
response to alcohol GO:0097305 48 0.033
cell growth GO:0016049 130 0.033
positive regulation of protein phosphorylation GO:0001934 242 0.033
regulation of carbohydrate catabolic process GO:0043470 12 0.032
Rat
reactive oxygen species metabolic process GO:0072593 84 0.032
forebrain development GO:0030900 302 0.032
peptidyl tyrosine modification GO:0018212 145 0.032
positive regulation of protein modification process GO:0031401 299 0.032
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.032
regulation of intracellular transport GO:0032386 159 0.032
hematopoietic progenitor cell differentiation GO:0002244 143 0.031
connective tissue replacement involved in inflammatory response wound healing GO:0002248 3 0.031
epithelial cell development GO:0002064 159 0.031
regulation of hormone secretion GO:0046883 88 0.031
transmembrane transport GO:0055085 412 0.031
response to metal ion GO:0010038 47 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.031
positive regulation of cell motility GO:2000147 116 0.031
generation of ovulation cycle rhythm GO:0060112 1 0.031
carbohydrate catabolic process GO:0016052 32 0.031
Rat
peptide hormone secretion GO:0030072 109 0.031
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.031
retina development in camera type eye GO:0060041 119 0.031
response to peptide GO:1901652 136 0.030
Rat
regulation of organelle organization GO:0033043 289 0.030
rhythmic process GO:0048511 174 0.030
positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774 13 0.030
response to radiation GO:0009314 165 0.030
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.030
visual behavior GO:0007632 45 0.030
positive regulation of secretion GO:0051047 130 0.030
cellular response to hormone stimulus GO:0032870 150 0.030
Rat
calcium ion transport into cytosol GO:0060402 48 0.030
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.029
second messenger mediated signaling GO:0019932 73 0.029
Rat
myeloid cell differentiation GO:0030099 233 0.029
organic cyclic compound catabolic process GO:1901361 295 0.029
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.029
lipid localization GO:0010876 126 0.029
negative regulation of transferase activity GO:0051348 85 0.029
response to inorganic substance GO:0010035 96 0.029
female sex differentiation GO:0046660 84 0.029
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.029
regulation of mapk cascade GO:0043408 248 0.029
regulation of peptide hormone secretion GO:0090276 75 0.028
glycogen metabolic process GO:0005977 32 0.028
Human Rat
intracellular receptor signaling pathway GO:0030522 74 0.028
small molecule biosynthetic process GO:0044283 132 0.028
inflammatory response GO:0006954 244 0.028
acetylcholine secretion neurotransmission GO:0014055 2 0.028
divalent metal ion transport GO:0070838 172 0.028
adult behavior GO:0030534 135 0.028
regulation of apoptotic signaling pathway GO:2001233 197 0.028
negative regulation of homeostatic process GO:0032845 71 0.028
cellular response to cytokine stimulus GO:0071345 189 0.028
regulation of insulin receptor signaling pathway GO:0046626 21 0.027
cellular response to growth factor stimulus GO:0071363 197 0.027
acetylcholine transport GO:0015870 2 0.027
negative regulation of tor signaling GO:0032007 13 0.027
circadian regulation of gene expression GO:0032922 48 0.027
associative learning GO:0008306 61 0.027
apoptotic signaling pathway GO:0097190 306 0.027
positive regulation of cell development GO:0010720 237 0.027
circadian rhythm GO:0007623 114 0.027
synapse organization GO:0050808 125 0.027
interaction with host GO:0051701 22 0.027
cellular response to glucose stimulus GO:0071333 45 0.026
protein oligomerization GO:0051259 67 0.026
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.026
regulation of cell growth GO:0001558 91 0.026
regulation of cell activation GO:0050865 289 0.025
blood circulation GO:0008015 195 0.025
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.025
negative regulation of t cell activation GO:0050868 65 0.025
cellular response to carbohydrate stimulus GO:0071322 50 0.025
telencephalon development GO:0021537 186 0.025
cellular response to abiotic stimulus GO:0071214 56 0.025
fat cell differentiation GO:0045444 160 0.025
modulation by virus of host morphology or physiology GO:0019048 3 0.024
cellular response to cadmium ion GO:0071276 3 0.024
regulation of protein serine threonine kinase activity GO:0071900 157 0.024
regulation of blood circulation GO:1903522 93 0.024
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.024
cell maturation GO:0048469 127 0.024
organelle assembly GO:0070925 177 0.024
acetate ester transport GO:1901374 2 0.024
regulation of protein kinase activity GO:0045859 232 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
heterocycle catabolic process GO:0046700 280 0.024
energy reserve metabolic process GO:0006112 39 0.024
Human Rat
vitamin d biosynthetic process GO:0042368 3 0.024
wound healing GO:0042060 157 0.024
circadian sleep wake cycle GO:0042745 5 0.024
learning or memory GO:0007611 148 0.024
multi multicellular organism process GO:0044706 109 0.023
cell substrate adhesion GO:0031589 130 0.023
purine nucleoside triphosphate catabolic process GO:0009146 203 0.023
embryonic placenta development GO:0001892 98 0.023
muscle cell cellular homeostasis GO:0046716 12 0.023
nuclear import GO:0051170 95 0.023
leukocyte differentiation GO:0002521 342 0.023
positive regulation of cellular carbohydrate metabolic process GO:0010676 29 0.023
Human Rat
regulation of t cell activation GO:0050863 170 0.023
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.023
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.023
alcohol metabolic process GO:0006066 116 0.023
connective tissue development GO:0061448 179 0.022
regulation of leukocyte proliferation GO:0070663 121 0.022
glucan metabolic process GO:0044042 32 0.022
Human Rat
cellular response to external stimulus GO:0071496 88 0.022
Rat
regulation of lymphocyte proliferation GO:0050670 117 0.022
lymphocyte homeostasis GO:0002260 64 0.022
regulation of hormone levels GO:0010817 211 0.022
developmental maturation GO:0021700 193 0.022
neuron migration GO:0001764 122 0.022
purine ribonucleotide biosynthetic process GO:0009152 59 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.021
regulation of lymphocyte apoptotic process GO:0070228 41 0.021
detection of abiotic stimulus GO:0009582 60 0.021
anion transport GO:0006820 177 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.021
divalent inorganic cation transport GO:0072511 178 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
small molecule catabolic process GO:0044282 71 0.021
regulation of multi organism process GO:0043900 111 0.021
cholesterol homeostasis GO:0042632 44 0.021
negative regulation of neuron apoptotic process GO:0043524 92 0.021
positive regulation of cell migration GO:0030335 109 0.021
organophosphate biosynthetic process GO:0090407 122 0.021
ion transmembrane transport GO:0034220 361 0.021
purine containing compound metabolic process GO:0072521 311 0.021
naphthalene containing compound metabolic process GO:0090420 1 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
activation of mapk activity GO:0000187 59 0.021
multicellular organism growth GO:0035264 161 0.021
baroreceptor response to decreased systemic arterial blood pressure GO:0001982 2 0.020
sensory perception of light stimulus GO:0050953 54 0.020
wound healing involved in inflammatory response GO:0002246 4 0.020
heart contraction GO:0060047 93 0.020
respiratory system development GO:0060541 190 0.020
steroid metabolic process GO:0008202 119 0.020
regulation of glycogen metabolic process GO:0070873 13 0.020
Human
cognition GO:0050890 149 0.020
t cell activation involved in immune response GO:0002286 43 0.020
pancreas development GO:0031016 57 0.020
interleukin 5 secretion GO:0072603 2 0.020
response to insulin GO:0032868 100 0.019
Rat
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
cilium assembly GO:0042384 81 0.019
negative regulation of interleukin 13 secretion GO:2000666 1 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
response to growth factor GO:0070848 198 0.019
regulation of intracellular protein transport GO:0033157 82 0.019
positive regulation of calcium ion transport GO:0051928 27 0.019
cellular response to peptide hormone stimulus GO:0071375 92 0.019
Rat
regulation of map kinase activity GO:0043405 120 0.019
sperm motility GO:0030317 47 0.019
negative regulation of neuron death GO:1901215 98 0.019
visual perception GO:0007601 52 0.019
smooth muscle contraction GO:0006939 44 0.019
regulation of reactive oxygen species metabolic process GO:2000377 40 0.018
regulation of endocytosis GO:0030100 69 0.018
cellular response to lipid GO:0071396 145 0.018
icosanoid metabolic process GO:0006690 33 0.018
cellular response to oxidative stress GO:0034599 76 0.018
cholesterol catabolic process GO:0006707 5 0.018
steroid biosynthetic process GO:0006694 47 0.018
lymphocyte activation involved in immune response GO:0002285 93 0.018
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.018
positive regulation of carbohydrate metabolic process GO:0045913 30 0.018
Human Rat
positive regulation of apoptotic process GO:0043065 217 0.018
endomembrane system organization GO:0010256 147 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.018
Rat
regulation of membrane potential GO:0042391 192 0.018
response to temperature stimulus GO:0009266 55 0.018
modification by symbiont of host morphology or physiology GO:0044003 4 0.018
epithelial cell proliferation GO:0050673 174 0.018
negative regulation of protein transport GO:0051224 46 0.017
epithelial cell migration GO:0010631 63 0.017
response to acid chemical GO:0001101 111 0.017
positive regulation of dopamine uptake involved in synaptic transmission GO:0051586 2 0.017
organic hydroxy compound biosynthetic process GO:1901617 77 0.017
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.017
glycoprotein biosynthetic process GO:0009101 89 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
hormone metabolic process GO:0042445 86 0.017
aromatic compound catabolic process GO:0019439 286 0.017
positive regulation of growth GO:0045927 104 0.017
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.017
regulation of leukocyte mediated immunity GO:0002703 104 0.017
defecation GO:0030421 1 0.017
cell adhesion GO:0007155 329 0.017
regulation of autophagic vacuole assembly GO:2000785 4 0.017
heart process GO:0003015 94 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
protein heterooligomerization GO:0051291 14 0.017
circulatory system process GO:0003013 197 0.017
regulation of adaptive immune response GO:0002819 90 0.017
polysaccharide metabolic process GO:0005976 39 0.016
Human Rat
organ growth GO:0035265 117 0.016
positive regulation of cell death GO:0010942 224 0.016
blood coagulation GO:0007596 76 0.016
nucleotide catabolic process GO:0009166 217 0.016
urogenital system development GO:0001655 261 0.016
negative regulation of cell activation GO:0050866 111 0.016
tissue homeostasis GO:0001894 115 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
cytosolic calcium ion transport GO:0060401 48 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
leukocyte migration GO:0050900 124 0.016
positive regulation of fatty acid oxidation GO:0046321 4 0.016
cellular response to hexose stimulus GO:0071331 47 0.016
response to activity GO:0014823 13 0.016
positive regulation of intracellular transport GO:0032388 70 0.016
regulation of blood pressure GO:0008217 93 0.016
calcium ion transport GO:0006816 159 0.016
regulation of protein localization to nucleus GO:1900180 60 0.016
erythrocyte differentiation GO:0030218 88 0.016
regulation of system process GO:0044057 200 0.015
organonitrogen compound catabolic process GO:1901565 264 0.015
regulation of organelle assembly GO:1902115 19 0.015
natural killer cell activation involved in immune response GO:0002323 10 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
germ cell development GO:0007281 185 0.015
leukocyte homeostasis GO:0001776 79 0.015
positive regulation of mammary gland involution GO:1903521 4 0.015
cellular transition metal ion homeostasis GO:0046916 32 0.015
immune effector process GO:0002252 321 0.015
interleukin 13 secretion GO:0072611 2 0.015
negative regulation of nervous system development GO:0051961 156 0.015
neural retina development GO:0003407 41 0.015
rhodopsin mediated signaling pathway GO:0016056 4 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
Rat
myoblast differentiation GO:0045445 52 0.015
germline stem cell asymmetric division GO:0098728 2 0.015
regulation of cytokine production GO:0001817 266 0.015
glycosyl compound catabolic process GO:1901658 206 0.015
male gamete generation GO:0048232 285 0.015
organophosphate catabolic process GO:0046434 232 0.014
release of sequestered calcium ion into cytosol GO:0051209 42 0.014
ossification GO:0001503 216 0.014
response to drug GO:0042493 75 0.014
lymphocyte apoptotic process GO:0070227 54 0.014
entry into host GO:0044409 15 0.014
protein tetramerization GO:0051262 23 0.014
calcium mediated signaling GO:0019722 46 0.014
movement in environment of other organism involved in symbiotic interaction GO:0052192 15 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
central nervous system neuron differentiation GO:0021953 162 0.014
regulation of cellular response to insulin stimulus GO:1900076 30 0.014
cellular response to lipopolysaccharide GO:0071222 77 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
regulation of vacuole organization GO:0044088 4 0.014
regulation of calcium ion transport GO:0051924 69 0.014
response to extracellular stimulus GO:0009991 127 0.014
Rat
peptidyl serine modification GO:0018209 83 0.014
neural precursor cell proliferation GO:0061351 121 0.014
regulation of proteolysis GO:0030162 164 0.014
response to reactive oxygen species GO:0000302 56 0.014
negative regulation of leukocyte differentiation GO:1902106 51 0.014
response to alkaline ph GO:0010446 1 0.014
negative regulation of t cell apoptotic process GO:0070233 18 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
neutral lipid metabolic process GO:0006638 57 0.014
atp metabolic process GO:0046034 75 0.014
exocrine pancreas development GO:0031017 7 0.014
negative regulation of lymphocyte activation GO:0051250 91 0.013
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.013
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.013
regulation of interleukin 5 secretion GO:2000662 2 0.013
cellular alcohol metabolic process GO:0044107 3 0.013
digestion GO:0007586 40 0.013
dendrite development GO:0016358 115 0.013
cerebellar purkinje cell layer morphogenesis GO:0021692 14 0.013
drug catabolic process GO:0042737 2 0.013
organic anion transport GO:0015711 137 0.013
amine metabolic process GO:0009308 45 0.013
acylglycerol metabolic process GO:0006639 55 0.013
renal system development GO:0072001 225 0.013
nucleoside catabolic process GO:0009164 206 0.013
response to steroid hormone GO:0048545 56 0.013
cytokine mediated signaling pathway GO:0019221 115 0.013
spermatogenesis GO:0007283 284 0.013
axonogenesis GO:0007409 274 0.013
regulation of t helper 2 cell cytokine production GO:2000551 3 0.013
positive regulation of immune effector process GO:0002699 107 0.013
cyclic nucleotide metabolic process GO:0009187 59 0.013
retinal cone cell differentiation GO:0042670 8 0.013
tetrapyrrole metabolic process GO:0033013 22 0.013
transition metal ion homeostasis GO:0055076 54 0.013

Gck disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.461
Human
inherited metabolic disorder DOID:655 0 0.167
Human
acquired metabolic disease DOID:0060158 0 0.163
Human
carbohydrate metabolic disorder DOID:2978 0 0.130
Human
hyperinsulinemic hypoglycemia DOID:13317 0 0.068
Human
obesity DOID:9970 0 0.056
nutrition disease DOID:374 0 0.056
overnutrition DOID:654 0 0.056
disease of anatomical entity DOID:7 0 0.016
musculoskeletal system disease DOID:17 0 0.016
immune system disease DOID:2914 0 0.014
hematopoietic system disease DOID:74 0 0.014