Mus musculus

93 known processes

Gdf6

growth differentiation factor 6

(Aliases: BMP13,GDF16)

Gdf6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
epiblast cell extraembryonic ectoderm cell signaling involved in anterior posterior axis specification GO:0060802 1 0.930
Mouse
heart trabecula formation GO:0060347 14 0.837
Mouse
mesendoderm development GO:0048382 3 0.692
Mouse
tendon cell differentiation GO:0035990 4 0.673
Mouse
positive regulation of tendon cell differentiation GO:2001051 1 0.601
Mouse
polarity specification of proximal distal axis GO:0010085 2 0.551
Mouse
roof plate formation GO:0021509 1 0.471
Mouse
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.464
Mouse
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.460
Mouse
trophectodermal cellular morphogenesis GO:0001831 3 0.445
Mouse
transforming growth factor beta receptor signaling pathway involved in primitive streak formation GO:0090010 1 0.442
Mouse
left lung morphogenesis GO:0060460 3 0.431
Mouse
positive regulation of dna endoreduplication GO:0032877 2 0.408
Worm
negative regulation of prostatic bud formation GO:0060686 4 0.402
Mouse
axial mesoderm formation GO:0048320 3 0.375
Mouse
axial mesodermal cell fate commitment GO:0048322 1 0.329
Mouse
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.325
Mouse
regulation of dna endoreduplication GO:0032875 3 0.321
Worm
defense response to bacterium GO:0042742 119 0.315
Worm
nephron development GO:0072006 109 0.313
Mouse
metanephric mesenchyme morphogenesis GO:0072133 4 0.270
Mouse
ureteric bud development GO:0001657 94 0.269
Mouse
defense response to other organism GO:0098542 197 0.263
Worm
kidney development GO:0001822 213 0.254
Mouse
muscle adaptation GO:0043500 39 0.254
Mouse
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.244
Mouse
axonogenesis GO:0007409 274 0.243
Zebrafish Mouse
regionalization GO:0003002 337 0.226
Zebrafish Mouse
axial mesodermal cell fate specification GO:0048327 1 0.223
Mouse
muscle tissue development GO:0060537 308 0.222
Zebrafish Mouse
negative regulation of stem cell maintenance GO:1902455 4 0.220
Mouse
morphogenesis of a branching structure GO:0001763 203 0.218
Mouse
bmp signaling pathway GO:0030509 93 0.207
respiratory tube development GO:0030323 167 0.203
Mouse
urogenital system development GO:0001655 261 0.202
Mouse
tendon formation GO:0035992 4 0.193
Mouse
nodal signaling pathway GO:0038092 10 0.181
Mouse
heart trabecula morphogenesis GO:0061384 26 0.180
Mouse
regulation of cell cycle GO:0051726 281 0.179
Worm
kidney epithelium development GO:0072073 121 0.168
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.150
Mouse
cardiac muscle cell development GO:0055013 39 0.142
Mouse
embryonic skeletal system development GO:0048706 120 0.137
Zebrafish Mouse
respiratory system development GO:0060541 190 0.135
Mouse
fat cell differentiation GO:0045444 160 0.133
Mouse
digestive system development GO:0055123 200 0.132
Mouse
cellular transition metal ion homeostasis GO:0046916 32 0.131
Mouse
forebrain morphogenesis GO:0048853 17 0.131
Mouse
mesonephros development GO:0001823 97 0.130
Mouse
cell type specific apoptotic process GO:0097285 268 0.130
Mouse
skeletal system development GO:0001501 356 0.129
Zebrafish Mouse
gastrulation GO:0007369 116 0.129
Mouse
defense response to gram positive bacterium GO:0050830 50 0.128
Worm
negative regulation of cell proliferation GO:0008285 296 0.127
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.127
Mouse
positive regulation of cell death GO:0010942 224 0.126
Mouse
cardiac chamber development GO:0003205 108 0.124
Mouse
regulation of cardiac muscle cell proliferation GO:0060043 23 0.123
Mouse
apoptotic process involved in morphogenesis GO:0060561 25 0.123
Mouse
amine metabolic process GO:0009308 45 0.122
smad protein signal transduction GO:0060395 21 0.120
Mouse
prostate gland morphogenesis GO:0060512 32 0.117
Mouse
odontogenesis of dentin containing tooth GO:0042475 66 0.116
Mouse
gland development GO:0048732 330 0.115
Mouse
mesenchymal stem cell maintenance involved in nephron morphogenesis GO:0072038 7 0.115
Mouse
cardiac muscle hypertrophy GO:0003300 23 0.115
Mouse
regulation of kidney development GO:0090183 40 0.115
Mouse
positive regulation of cardiac muscle tissue development GO:0055025 19 0.114
Mouse
cardiac muscle tissue development GO:0048738 130 0.114
Mouse
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.114
Mouse
dna metabolic process GO:0006259 303 0.113
Worm
energy homeostasis GO:0097009 15 0.111
Mouse
spinal cord association neuron differentiation GO:0021527 14 0.111
Mouse
cell differentiation in spinal cord GO:0021515 53 0.111
Mouse
transition metal ion homeostasis GO:0055076 54 0.110
Mouse
placenta development GO:0001890 140 0.110
Mouse
regulation of receptor activity GO:0010469 41 0.108
Mouse
positive regulation of epithelial cell proliferation GO:0050679 68 0.105
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.104
Mouse
negative regulation of cell development GO:0010721 169 0.101
Mouse
multicellular organism growth GO:0035264 161 0.101
Mouse Worm
regulation of apoptotic process involved in morphogenesis GO:1902337 10 0.100
Mouse
neuroepithelial cell differentiation GO:0060563 37 0.099
Mouse
positive regulation of protein modification process GO:0031401 299 0.098
Human Mouse
muscle system process GO:0003012 141 0.096
Mouse
renal system development GO:0072001 225 0.096
Mouse
hepaticobiliary system development GO:0061008 67 0.094
Mouse
epithelial cell proliferation GO:0050673 174 0.092
Mouse
regulation of organ morphogenesis GO:2000027 144 0.091
Mouse
cellular homeostasis GO:0019725 240 0.090
Mouse
ventricular cardiac muscle cell differentiation GO:0055012 17 0.089
Mouse
kidney morphogenesis GO:0060993 83 0.087
Mouse
male gamete generation GO:0048232 285 0.087
Mouse
morphogenesis of an epithelial fold GO:0060571 28 0.085
Mouse
regulation of vasculature development GO:1901342 88 0.084
Mouse
mesonephric epithelium development GO:0072163 94 0.084
Mouse
central nervous system neuron differentiation GO:0021953 162 0.083
Mouse
blastocyst development GO:0001824 80 0.082
Mouse
dorsal spinal cord development GO:0021516 20 0.082
Mouse
muscle tissue morphogenesis GO:0060415 53 0.081
Mouse
digestive tract development GO:0048565 190 0.080
Mouse
striated muscle tissue development GO:0014706 293 0.079
Zebrafish Mouse
lung morphogenesis GO:0060425 50 0.079
Mouse
regulation of homeostatic process GO:0032844 182 0.079
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.079
Mouse
camera type eye development GO:0043010 266 0.076
Zebrafish Mouse
innate immune response GO:0045087 157 0.075
Worm
atrial cardiac muscle tissue development GO:0003228 5 0.075
Mouse
striated muscle cell development GO:0055002 125 0.075
Zebrafish Mouse
chondrocyte differentiation GO:0002062 72 0.075
Mouse
blood vessel morphogenesis GO:0048514 285 0.074
Zebrafish Mouse
cell fate commitment GO:0045165 210 0.074
Mouse
heart morphogenesis GO:0003007 178 0.074
Mouse
regulation of tendon cell differentiation GO:2001049 1 0.073
Mouse
regulation of cardiac muscle tissue development GO:0055024 31 0.072
Mouse
leukocyte differentiation GO:0002521 342 0.071
cellular chemical homeostasis GO:0055082 215 0.071
Mouse
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.071
Mouse
iron ion homeostasis GO:0055072 36 0.071
Mouse
trophectodermal cell differentiation GO:0001829 21 0.071
Mouse
sensory organ morphogenesis GO:0090596 242 0.070
Zebrafish Mouse
cellular amine metabolic process GO:0044106 44 0.070
organ growth GO:0035265 117 0.069
Mouse Worm
regulation of cellular amine metabolic process GO:0033238 20 0.069
mesenchyme development GO:0060485 152 0.069
Mouse
regulation of cardiac muscle tissue growth GO:0055021 26 0.068
Mouse
muscle cell development GO:0055001 133 0.068
Zebrafish Mouse
somatic sex determination GO:0018993 2 0.067
epithelial tube morphogenesis GO:0060562 303 0.067
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.066
Mouse
chemotaxis GO:0006935 247 0.066
Zebrafish Mouse
neuron projection guidance GO:0097485 141 0.066
Zebrafish Mouse
skeletal system morphogenesis GO:0048705 203 0.066
Mouse
response to extracellular stimulus GO:0009991 127 0.066
Mouse
metanephros development GO:0001656 79 0.066
Mouse
cellular metal ion homeostasis GO:0006875 151 0.066
Mouse
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.065
Mouse
cellular amino acid metabolic process GO:0006520 103 0.065
ameboidal type cell migration GO:0001667 128 0.065
Mouse
response to transforming growth factor beta GO:0071559 88 0.064
Mouse
embryonic organ morphogenesis GO:0048562 276 0.063
Mouse
ventricular cardiac muscle tissue development GO:0003229 38 0.063
Mouse
metanephric mesenchymal cell proliferation involved in metanephros development GO:0072136 2 0.063
Mouse
cartilage development GO:0051216 140 0.063
Mouse
digestive tract morphogenesis GO:0048546 147 0.063
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.062
Human Zebrafish Mouse
prostate gland development GO:0030850 48 0.061
Mouse
ventricular cardiac muscle cell development GO:0055015 11 0.061
Mouse
primitive streak formation GO:0090009 10 0.060
Mouse
embryonic placenta development GO:0001892 98 0.060
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.059
Human Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.059
kidney mesenchyme development GO:0072074 14 0.059
Mouse
cardiac muscle tissue growth GO:0055017 37 0.058
Mouse
cardiocyte differentiation GO:0035051 87 0.058
Mouse
negative regulation of mesenchymal cell apoptotic process GO:2001054 11 0.057
Mouse
striated muscle cell proliferation GO:0014855 39 0.057
Mouse
cellular iron ion homeostasis GO:0006879 16 0.057
Mouse
maternal process involved in female pregnancy GO:0060135 32 0.057
Mouse
mapk cascade GO:0000165 281 0.057
Mouse
endochondral bone morphogenesis GO:0060350 50 0.056
Mouse
cell adhesion GO:0007155 329 0.056
odontogenesis GO:0042476 78 0.056
Mouse
synaptic transmission GO:0007268 329 0.056
kidney mesenchyme morphogenesis GO:0072131 4 0.056
Mouse
positive regulation of apoptotic process GO:0043065 217 0.056
Mouse
positive regulation of angiogenesis GO:0045766 46 0.056
Mouse
forebrain development GO:0030900 302 0.055
Mouse
regulation of heart growth GO:0060420 31 0.055
Mouse
inhibition of neuroepithelial cell differentiation GO:0002085 2 0.055
Mouse
extracellular structure organization GO:0043062 148 0.055
ossification GO:0001503 216 0.055
Mouse
cardiac muscle cell differentiation GO:0055007 69 0.054
Mouse
positive regulation of organ growth GO:0046622 29 0.053
Mouse Worm
forelimb morphogenesis GO:0035136 40 0.053
Mouse
cation homeostasis GO:0055080 212 0.053
Mouse
cardiac muscle cell proliferation GO:0060038 31 0.053
Mouse
regulation of stem cell differentiation GO:2000736 50 0.052
Mouse
epithelial tube formation GO:0072175 130 0.052
Mouse
positive regulation of cell development GO:0010720 237 0.052
germ cell development GO:0007281 185 0.052
Mouse
branching involved in salivary gland morphogenesis GO:0060445 26 0.051
Mouse
positive regulation of cell cycle process GO:0090068 61 0.051
Worm
embryonic epithelial tube formation GO:0001838 130 0.050
Mouse
cardiac atrium morphogenesis GO:0003209 23 0.050
Mouse
stem cell proliferation GO:0072089 117 0.050
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.049
liver development GO:0001889 66 0.049
Mouse
brain morphogenesis GO:0048854 32 0.049
Mouse
positive regulation of endothelial cell proliferation GO:0001938 17 0.049
Mouse
regulation of embryonic development GO:0045995 71 0.049
Mouse
positive regulation of nervous system development GO:0051962 221 0.049
muscle cell differentiation GO:0042692 261 0.049
Zebrafish Mouse
paraxial mesodermal cell differentiation GO:0048342 2 0.049
protein maturation GO:0051604 176 0.048
male sex differentiation GO:0046661 109 0.048
Mouse Worm
gastrulation with mouth forming second GO:0001702 29 0.048
Mouse
skin development GO:0043588 220 0.047
regulation of transferase activity GO:0051338 263 0.047
axon guidance GO:0007411 141 0.046
Zebrafish Mouse
renal tubule development GO:0061326 87 0.046
morphogenesis of an epithelial bud GO:0060572 18 0.046
Mouse
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.046
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
regulation of lymphocyte activation GO:0051249 240 0.045
cardiac cell development GO:0055006 41 0.045
Mouse
regulation of angiogenesis GO:0045765 81 0.045
Mouse
limb development GO:0060173 166 0.044
Mouse
regulation of neuron differentiation GO:0045664 281 0.044
negative regulation of cellular amine metabolic process GO:0033239 1 0.044
negative regulation of neuron differentiation GO:0045665 101 0.044
Mouse
regulation of heart morphogenesis GO:2000826 22 0.044
Mouse
heart growth GO:0060419 45 0.044
Mouse
diet induced thermogenesis GO:0002024 7 0.044
Mouse
nephron morphogenesis GO:0072028 69 0.044
Mouse
ureteric bud morphogenesis GO:0060675 62 0.044
primary neural tube formation GO:0014020 95 0.043
Mouse
macromolecule catabolic process GO:0009057 281 0.042
embryonic eye morphogenesis GO:0048048 29 0.042
Mouse
negative regulation of reproductive process GO:2000242 31 0.041
Mouse
cellular ion homeostasis GO:0006873 165 0.041
Mouse
extracellular matrix organization GO:0030198 147 0.041
regulation of kinase activity GO:0043549 249 0.040
mesodermal cell fate commitment GO:0001710 17 0.040
Mouse
embryonic appendage morphogenesis GO:0035113 126 0.040
Mouse
exocrine system development GO:0035272 45 0.040
Mouse
atrial cardiac muscle tissue morphogenesis GO:0055009 5 0.040
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.040
positive regulation of programmed cell death GO:0043068 218 0.039
Mouse
lung development GO:0030324 164 0.039
Mouse
cardiac ventricle morphogenesis GO:0003208 50 0.039
Mouse
regulation of cell size GO:0008361 72 0.039
Worm
regulation of morphogenesis of a branching structure GO:0060688 53 0.039
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.038
Mouse
positive regulation of endothelial cell differentiation GO:0045603 7 0.038
Mouse
muscle cell proliferation GO:0033002 52 0.038
Mouse
negative regulation of nervous system development GO:0051961 156 0.038
Mouse
defense response to gram negative bacterium GO:0050829 28 0.038
Worm
telencephalon development GO:0021537 186 0.038
axial mesoderm morphogenesis GO:0048319 5 0.038
Mouse
embryonic skeletal joint morphogenesis GO:0060272 11 0.038
Mouse
negative regulation of muscle hypertrophy GO:0014741 9 0.037
Mouse
determination of left right symmetry GO:0007368 80 0.037
Mouse
striated muscle hypertrophy GO:0014897 24 0.037
Mouse
regulation of organ formation GO:0003156 34 0.037
Mouse
metanephric mesenchyme development GO:0072075 10 0.037
Mouse
dna replication GO:0006260 52 0.037
Worm
endothelial cell proliferation GO:0001935 27 0.037
Mouse
regulation of reproductive process GO:2000241 66 0.037
Mouse
cell proliferation involved in heart morphogenesis GO:0061323 15 0.037
Mouse
neural fold formation GO:0001842 7 0.036
Mouse
regulation of multicellular organismal metabolic process GO:0044246 14 0.036
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.035
Mouse
formation of primary germ layer GO:0001704 77 0.035
Mouse
trabecula formation GO:0060343 24 0.035
Mouse
mesoderm development GO:0007498 100 0.034
Mouse
spermatogenesis GO:0007283 284 0.034
Mouse
renal tubule morphogenesis GO:0061333 72 0.034
t cell differentiation GO:0030217 174 0.034
positive regulation of striated muscle tissue development GO:0045844 31 0.033
Mouse
regulation of t cell activation GO:0050863 170 0.033
oxidation reduction process GO:0055114 342 0.033
carbohydrate metabolic process GO:0005975 230 0.033
b cell activation GO:0042113 161 0.033
positive regulation of cell cycle GO:0045787 92 0.033
Worm
embryonic process involved in female pregnancy GO:0060136 7 0.033
Mouse
mesonephric tubule development GO:0072164 94 0.033
Mouse
nephron epithelium morphogenesis GO:0072088 68 0.032
epithelial cell development GO:0002064 159 0.032
g protein coupled receptor signaling pathway GO:0007186 243 0.032
cardiac ventricle development GO:0003231 83 0.032
Mouse
negative regulation of notch signaling pathway GO:0045746 14 0.032
Mouse
formation of anatomical boundary GO:0048859 6 0.031
Mouse
developmental maturation GO:0021700 193 0.031
dna dependent dna replication GO:0006261 24 0.031
Worm
mesenchyme morphogenesis GO:0072132 32 0.031
Mouse
embryonic limb morphogenesis GO:0030326 126 0.030
Mouse
hexose metabolic process GO:0019318 98 0.030
embryonic camera type eye development GO:0031076 36 0.030
Zebrafish Mouse
stem cell development GO:0048864 219 0.030
Mouse
ectoderm formation GO:0001705 3 0.029
regulation of apoptotic signaling pathway GO:2001233 197 0.029
t cell activation GO:0042110 289 0.029
cellular macromolecule catabolic process GO:0044265 206 0.029
protein catabolic process GO:0030163 221 0.028
positive regulation of neuron differentiation GO:0045666 141 0.028
multi multicellular organism process GO:0044706 109 0.028
Mouse
regulation of timing of cell differentiation GO:0048505 11 0.028
Mouse
cellular response to lipid GO:0071396 145 0.028
tendon development GO:0035989 6 0.028
Mouse
cardiac atrium development GO:0003230 24 0.028
Mouse
paraxial mesodermal cell fate commitment GO:0048343 2 0.028
negative regulation of immune system process GO:0002683 209 0.028
pyramidal neuron migration GO:0021852 1 0.028
organic cyclic compound catabolic process GO:1901361 295 0.027
response to dietary excess GO:0002021 18 0.027
Mouse
regulation of defense response GO:0031347 233 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
nephron epithelium development GO:0072009 92 0.027
apoptotic signaling pathway GO:0097190 306 0.027
kidney mesenchymal cell proliferation GO:0072135 2 0.026
Mouse
multicellular organismal signaling GO:0035637 91 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
connective tissue development GO:0061448 179 0.026
Mouse
bone development GO:0060348 120 0.026
Mouse
embryonic heart tube morphogenesis GO:0003143 51 0.026
Mouse
response to organonitrogen compound GO:0010243 246 0.026
lymphocyte differentiation GO:0030098 242 0.026
negative regulation of cardiac muscle hypertrophy GO:0010614 9 0.026
Mouse
nephrogenic mesenchyme development GO:0072076 3 0.025
Mouse
response to nutrient levels GO:0031667 109 0.025
Mouse
immune response regulating signaling pathway GO:0002764 125 0.025
skeletal muscle cell differentiation GO:0035914 66 0.025
negative regulation of stem cell differentiation GO:2000737 14 0.025
Mouse
heterocycle catabolic process GO:0046700 280 0.025
nephron tubule morphogenesis GO:0072078 68 0.025
regulation of gastrulation GO:0010470 16 0.025
Mouse
epidermis development GO:0008544 187 0.025
regulation of mapk cascade GO:0043408 248 0.025
Mouse
endoderm development GO:0007492 45 0.024
Mouse
positive regulation of growth GO:0045927 104 0.024
Mouse Worm
nucleotide metabolic process GO:0009117 332 0.024
cell substrate adhesion GO:0031589 130 0.024
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.024
Mouse
regulation of muscle hypertrophy GO:0014743 13 0.024
Mouse
regulation of muscle adaptation GO:0043502 31 0.024
Mouse
positive regulation of cell proliferation involved in heart morphogenesis GO:2000138 5 0.024
Mouse
positive regulation of transferase activity GO:0051347 167 0.024
sensory perception GO:0007600 245 0.024
mesenchymal cell proliferation GO:0010463 44 0.024
Mouse
regulation of endothelial cell proliferation GO:0001936 23 0.023
Mouse
wnt signaling pathway GO:0016055 188 0.023
hindlimb morphogenesis GO:0035137 42 0.023
Mouse
regulation of cell cycle process GO:0010564 160 0.023
Worm
protein modification by small protein conjugation GO:0032446 187 0.023
regulation of membrane potential GO:0042391 192 0.023
positive regulation of dna replication GO:0045740 9 0.023
Worm
positive regulation of cartilage development GO:0061036 18 0.023
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.023
female sex determination GO:0030237 1 0.022
regulation of vascular wound healing GO:0061043 2 0.022
hematopoietic progenitor cell differentiation GO:0002244 143 0.022
somatic stem cell maintenance GO:0035019 47 0.022
Mouse
skeletal muscle organ development GO:0060538 163 0.022
Zebrafish
tube formation GO:0035148 140 0.022
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.022
branching involved in ureteric bud morphogenesis GO:0001658 56 0.022
regulation of muscle tissue development GO:1901861 97 0.022
Mouse
positive regulation of receptor activity GO:2000273 17 0.022
Mouse
transmission of nerve impulse GO:0019226 76 0.021
compound eye development GO:0048749 1 0.021
sensory system development GO:0048880 3 0.021
negative regulation of cell activation GO:0050866 111 0.021
regulation of anatomical structure size GO:0090066 178 0.021
Worm
spinal cord development GO:0021510 81 0.021
Mouse
monosaccharide metabolic process GO:0005996 106 0.021
positive regulation of protein kinase activity GO:0045860 144 0.021
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
protein processing GO:0016485 163 0.021
appendage morphogenesis GO:0035107 149 0.021
Mouse
lateral sprouting from an epithelium GO:0060601 13 0.021
Mouse
rhythmic process GO:0048511 174 0.021
nephron tubule development GO:0072080 84 0.020
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.020
Mouse
negative regulation of cellular component organization GO:0051129 194 0.020
negative regulation of transferase activity GO:0051348 85 0.020
regulation of organelle organization GO:0033043 289 0.020
replacement ossification GO:0036075 26 0.020
Mouse
positive regulation of muscle tissue development GO:1901863 32 0.020
Mouse
lymphocyte mediated immunity GO:0002449 139 0.020
neuronal action potential GO:0019228 54 0.020
glucose homeostasis GO:0042593 128 0.020
cellular response to amino acid stimulus GO:0071230 29 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
purine containing compound metabolic process GO:0072521 311 0.019
inorganic cation transmembrane transport GO:0098662 207 0.019
regulation of cell adhesion GO:0030155 154 0.019
positive regulation of chondrocyte differentiation GO:0032332 13 0.019
Mouse
activation of immune response GO:0002253 138 0.019
bone morphogenesis GO:0060349 78 0.019
Mouse
pallium development GO:0021543 120 0.019
cell fate specification GO:0001708 72 0.019
Mouse
modification dependent macromolecule catabolic process GO:0043632 133 0.019
fertilization GO:0009566 127 0.019
peptidyl tyrosine modification GO:0018212 145 0.019
ras protein signal transduction GO:0007265 77 0.019
regulation of protein kinase activity GO:0045859 232 0.019
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.019
mesodermal cell differentiation GO:0048333 22 0.019
Mouse
endocytosis GO:0006897 168 0.019
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.019
negative regulation of molecular function GO:0044092 258 0.019
female somatic sex determination GO:0019101 1 0.019
pathway restricted smad protein phosphorylation GO:0060389 10 0.019
Human Mouse
cellular ketone metabolic process GO:0042180 84 0.019
cellular lipid metabolic process GO:0044255 323 0.019
cation transmembrane transport GO:0098655 266 0.019
regulation of wnt signaling pathway GO:0030111 123 0.019
regulation of cell projection organization GO:0031344 206 0.018
regulation of cytokine production GO:0001817 266 0.018
glucose metabolic process GO:0006006 92 0.018
female sex differentiation GO:0046660 84 0.018
action potential GO:0001508 78 0.018
retina development in camera type eye GO:0060041 119 0.018
Zebrafish
negative regulation of kinase activity GO:0033673 81 0.018
hormone metabolic process GO:0042445 86 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
regulation of cell activation GO:0050865 289 0.018
single organismal cell cell adhesion GO:0016337 131 0.018
cell proliferation involved in metanephros development GO:0072203 9 0.018
Mouse
wound healing GO:0042060 157 0.018
regulation of cardiac muscle hypertrophy GO:0010611 13 0.017
Mouse
microtubule based process GO:0007017 236 0.017
b cell differentiation GO:0030183 78 0.017
maternal process involved in parturition GO:0060137 1 0.017
Mouse
cellular carbohydrate metabolic process GO:0044262 119 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.017
regulation of muscle system process GO:0090257 80 0.017
Mouse
ear development GO:0043583 200 0.017
immune effector process GO:0002252 321 0.017
neural precursor cell proliferation GO:0061351 121 0.017
positive regulation of lymphocyte activation GO:0051251 140 0.017
cerebellum morphogenesis GO:0021587 42 0.017
myeloid cell differentiation GO:0030099 233 0.017
development of primary female sexual characteristics GO:0046545 73 0.017
salivary gland morphogenesis GO:0007435 33 0.017
Mouse
heart contraction GO:0060047 93 0.017
branching involved in prostate gland morphogenesis GO:0060442 15 0.017
Mouse
homeostasis of number of cells GO:0048872 210 0.017
positive regulation of organelle organization GO:0010638 128 0.017
floor plate morphogenesis GO:0033505 3 0.017
Mouse
negative regulation of epithelial cell proliferation GO:0050680 64 0.017
regulation of myeloid leukocyte differentiation GO:0002761 58 0.017
cell activation involved in immune response GO:0002263 126 0.017
limb morphogenesis GO:0035108 149 0.017
Mouse
t cell differentiation in thymus GO:0033077 77 0.016
membrane organization GO:0061024 245 0.016
dna recombination GO:0006310 92 0.016
glomerular mesangial cell development GO:0072144 3 0.016
transmembrane transport GO:0055085 412 0.016
regulation of chondrocyte differentiation GO:0032330 33 0.016
Mouse
positive regulation of leukocyte differentiation GO:1902107 86 0.016
protein ubiquitination GO:0016567 171 0.016
cytokine production GO:0001816 319 0.016
telencephalon cell migration GO:0022029 55 0.016
forebrain cell migration GO:0021885 58 0.016
blood circulation GO:0008015 195 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
somatotropin secreting cell differentiation GO:0060126 4 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
male genitalia development GO:0030539 20 0.016
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.016
regulation of protein processing GO:0070613 96 0.016
cellular response to biotic stimulus GO:0071216 92 0.015
palate development GO:0060021 76 0.015
positive regulation of mapk cascade GO:0043410 170 0.015
regulation of lymphocyte differentiation GO:0045619 107 0.015
glomerular mesangial cell differentiation GO:0072008 3 0.015
cell maturation GO:0048469 127 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
developmental growth involved in morphogenesis GO:0060560 138 0.015
response to amino acid GO:0043200 37 0.015
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.015
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.015
stem cell differentiation GO:0048863 268 0.015
Mouse
glial cell differentiation GO:0010001 131 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
mesenchymal cell apoptotic process GO:0097152 14 0.015
Mouse
ion transmembrane transport GO:0034220 361 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.014
midbrain development GO:0030901 35 0.014
Mouse
negative regulation of embryonic development GO:0045992 22 0.014
Mouse
collagen fibril organization GO:0030199 32 0.014
purine containing compound catabolic process GO:0072523 213 0.014
regulation of hydrolase activity GO:0051336 246 0.014
ovulation cycle GO:0042698 59 0.014
renal capsule specification GO:0072130 1 0.014
lateral inhibition GO:0046331 1 0.014
modification dependent protein catabolic process GO:0019941 133 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
mesodermal cell fate specification GO:0007501 11 0.014
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.014

Gdf6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.094
Human
musculoskeletal system disease DOID:17 0 0.094
connective tissue disease DOID:65 0 0.043
osteochondrodysplasia DOID:2256 0 0.027
bone development disease DOID:0080006 0 0.027
bone disease DOID:0080001 0 0.027
sensory system disease DOID:0050155 0 0.018
Human
eye and adnexa disease DOID:1492 0 0.018
Human
nervous system disease DOID:863 0 0.018
Human
eye disease DOID:5614 0 0.018
Human