Mus musculus

0 known processes

Gfm1

G elongation factor, mitochondrial 1

(Aliases: Gfm,AW545374,D3Wsu133e)

Gfm1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
generation of precursor metabolites and energy GO:0006091 103 0.338
mitochondrial translation GO:0032543 4 0.269
Human Yeast
mitochondrion organization GO:0007005 134 0.238
Human Yeast
coenzyme metabolic process GO:0006732 52 0.172
purine ribonucleotide metabolic process GO:0009150 290 0.135
Human
thioester metabolic process GO:0035383 19 0.131
cellular respiration GO:0045333 38 0.129
energy derivation by oxidation of organic compounds GO:0015980 77 0.116
oxidation reduction process GO:0055114 342 0.113
nucleobase containing small molecule metabolic process GO:0055086 352 0.109
Human
acyl coa biosynthetic process GO:0071616 7 0.109
acetyl coa biosynthetic process GO:0006085 5 0.107
cellular amino acid metabolic process GO:0006520 103 0.092
nadh metabolic process GO:0006734 1 0.088
cellular ketone metabolic process GO:0042180 84 0.087
acetyl coa biosynthetic process from pyruvate GO:0006086 3 0.083
nucleoside phosphate metabolic process GO:0006753 338 0.076
Human
thioester biosynthetic process GO:0035384 7 0.073
regulation of membrane potential GO:0042391 192 0.067
coenzyme biosynthetic process GO:0009108 23 0.064
macromolecule catabolic process GO:0009057 281 0.062
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.061
Human
dna metabolic process GO:0006259 303 0.054
multicellular organismal homeostasis GO:0048871 164 0.053
purine nucleoside triphosphate metabolic process GO:0009144 226 0.051
Human
sulfur compound biosynthetic process GO:0044272 37 0.050
protein processing GO:0016485 163 0.050
response to oxidative stress GO:0006979 123 0.048
purine nucleotide metabolic process GO:0006163 302 0.045
Human
regulation of cellular ketone metabolic process GO:0010565 66 0.041
neuron apoptotic process GO:0051402 142 0.041
purine nucleoside monophosphate metabolic process GO:0009126 81 0.040
sulfur compound metabolic process GO:0006790 100 0.040
purine containing compound metabolic process GO:0072521 311 0.039
Human
pyridine containing compound catabolic process GO:0072526 4 0.038
defecation GO:0030421 1 0.038
nucleotide metabolic process GO:0009117 332 0.037
Human
cellular homeostasis GO:0019725 240 0.037
intrinsic apoptotic signaling pathway GO:0097193 132 0.036
regulation of cellular catabolic process GO:0031329 242 0.035
purine ribonucleoside metabolic process GO:0046128 241 0.035
Human
ribose phosphate metabolic process GO:0019693 291 0.034
Human
mitochondrial membrane organization GO:0007006 26 0.033
cellular macromolecule catabolic process GO:0044265 206 0.033
organic cyclic compound catabolic process GO:1901361 295 0.032
Human
regulation of mitochondrial membrane potential GO:0051881 17 0.032
cellular modified amino acid metabolic process GO:0006575 63 0.032
protein targeting GO:0006605 143 0.032
transmembrane transport GO:0055085 412 0.032
nucleoside metabolic process GO:0009116 246 0.031
Human
positive regulation of growth GO:0045927 104 0.031
regulation of organelle organization GO:0033043 289 0.031
atp metabolic process GO:0046034 75 0.031
nucleoside triphosphate metabolic process GO:0009141 230 0.030
Human
male gamete generation GO:0048232 285 0.030
lipid biosynthetic process GO:0008610 179 0.030
mitochondrion morphogenesis GO:0070584 13 0.029
heterocycle catabolic process GO:0046700 280 0.028
Human
mitochondrion degradation GO:0000422 3 0.027
regulation of cellular amino acid metabolic process GO:0006521 5 0.027
protein localization to organelle GO:0033365 185 0.027
response to endoplasmic reticulum stress GO:0034976 53 0.027
protein maturation GO:0051604 176 0.026
multicellular organism growth GO:0035264 161 0.026
regulation of cellular response to stress GO:0080135 159 0.026
cristae formation GO:0042407 3 0.025
cofactor biosynthetic process GO:0051188 41 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
Human
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
Human
cell type specific apoptotic process GO:0097285 268 0.024
action potential GO:0001508 78 0.024
regulation of mitochondrial translation GO:0070129 3 0.024
dephosphorylation GO:0016311 129 0.024
cation homeostasis GO:0055080 212 0.024
homeostasis of number of cells GO:0048872 210 0.023
regulation of hydrolase activity GO:0051336 246 0.023
cellular metal ion homeostasis GO:0006875 151 0.023
regulation of cell activation GO:0050865 289 0.022
mitochondrial protein processing GO:0034982 5 0.022
locomotory behavior GO:0007626 195 0.022
aromatic compound catabolic process GO:0019439 286 0.022
Human
intracellular protein transport GO:0006886 204 0.022
apoptotic signaling pathway GO:0097190 306 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
cellular chemical homeostasis GO:0055082 215 0.022
glycosyl compound metabolic process GO:1901657 246 0.022
Human
positive regulation of protein modification process GO:0031401 299 0.022
purine nucleoside metabolic process GO:0042278 241 0.021
Human
ribonucleoside monophosphate metabolic process GO:0009161 80 0.021
inner mitochondrial membrane organization GO:0007007 5 0.021
chromatin organization GO:0006325 206 0.021
nucleoside monophosphate metabolic process GO:0009123 85 0.021
spermatogenesis GO:0007283 284 0.021
sensory perception GO:0007600 245 0.020
regulation of mitochondrion organization GO:0010821 27 0.020
mitochondrial respiratory chain complex assembly GO:0033108 2 0.020
protein processing involved in protein targeting to mitochondrion GO:0006627 1 0.020
cellular protein complex assembly GO:0043623 116 0.020
transmission of nerve impulse GO:0019226 76 0.020
metal ion homeostasis GO:0055065 189 0.020
establishment of protein localization to organelle GO:0072594 118 0.019
dna catabolic process endonucleolytic GO:0000737 15 0.019
nitrogen compound transport GO:0071705 271 0.019
epithelial tube morphogenesis GO:0060562 303 0.019
atp synthesis coupled electron transport GO:0042773 8 0.019
response to reactive oxygen species GO:0000302 56 0.018
cellular nitrogen compound catabolic process GO:0044270 280 0.018
Human
cellular response to oxidative stress GO:0034599 76 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
Human
ion transmembrane transport GO:0034220 361 0.018
response to organonitrogen compound GO:0010243 246 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
muscle cell differentiation GO:0042692 261 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
embryonic epithelial tube formation GO:0001838 130 0.018
regulation of lymphocyte activation GO:0051249 240 0.017
protein import GO:0017038 101 0.017
gland development GO:0048732 330 0.017
neuronal action potential GO:0019228 54 0.017
lymphocyte differentiation GO:0030098 242 0.017
positive regulation of cell death GO:0010942 224 0.017
amine metabolic process GO:0009308 45 0.017
cellular amine metabolic process GO:0044106 44 0.016
immune effector process GO:0002252 321 0.016
morphogenesis of embryonic epithelium GO:0016331 159 0.016
response to extracellular stimulus GO:0009991 127 0.016
hepaticobiliary system development GO:0061008 67 0.016
citrate metabolic process GO:0006101 3 0.016
neural tube formation GO:0001841 108 0.016
defense response to other organism GO:0098542 197 0.016
multicellular organismal signaling GO:0035637 91 0.016
negative regulation of immune system process GO:0002683 209 0.015
dicarboxylic acid metabolic process GO:0043648 18 0.015
neural tube development GO:0021915 160 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
lymphocyte homeostasis GO:0002260 64 0.015
inflammatory response GO:0006954 244 0.015
camera type eye development GO:0043010 266 0.015
negative regulation of cell development GO:0010721 169 0.015
response to inorganic substance GO:0010035 96 0.015
leukocyte mediated immunity GO:0002443 174 0.015
inorganic cation transmembrane transport GO:0098662 207 0.014
lymphocyte proliferation GO:0046651 164 0.014
protein catabolic process GO:0030163 221 0.014
leukocyte homeostasis GO:0001776 79 0.014
regulation of homeostatic process GO:0032844 182 0.014
regulation of secretion by cell GO:1903530 249 0.014
cellular amide metabolic process GO:0043603 58 0.014
cytoplasmic transport GO:0016482 234 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.014
small molecule biosynthetic process GO:0044283 132 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
t cell activation GO:0042110 289 0.014
regulation of cellular amine metabolic process GO:0033238 20 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
leukocyte differentiation GO:0002521 342 0.014
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.014
t cell proliferation GO:0042098 120 0.014
regulation of response to wounding GO:1903034 189 0.013
tube formation GO:0035148 140 0.013
multi multicellular organism process GO:0044706 109 0.013
regulation of mitochondrial fission GO:0090140 3 0.013
regulation of secretion GO:0051046 274 0.013
neuron death GO:0070997 154 0.013
maintenance of location GO:0051235 89 0.013
dna catabolic process GO:0006308 19 0.013
amide transport GO:0042886 138 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
regulation of t cell activation GO:0050863 170 0.013
regulation of fat cell differentiation GO:0045598 81 0.013
regulation of body fluid levels GO:0050878 162 0.013
t cell differentiation GO:0030217 174 0.012
positive regulation of cell activation GO:0050867 158 0.012
cytokine production GO:0001816 319 0.012
positive regulation of organelle organization GO:0010638 128 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
quinone biosynthetic process GO:1901663 4 0.012
ensheathment of neurons GO:0007272 76 0.012
regulation of protein maturation GO:1903317 96 0.012
blastocyst development GO:0001824 80 0.012
response to nutrient levels GO:0031667 109 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
adult behavior GO:0030534 135 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
renal system development GO:0072001 225 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
pyridine containing compound metabolic process GO:0072524 14 0.012
heart morphogenesis GO:0003007 178 0.012
cofactor transport GO:0051181 4 0.012
divalent metal ion transport GO:0070838 172 0.012
anatomical structure homeostasis GO:0060249 145 0.012
myelination GO:0042552 74 0.012
tissue homeostasis GO:0001894 115 0.012
alpha amino acid metabolic process GO:1901605 59 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
response to hyperoxia GO:0055093 2 0.011
peptidyl amino acid modification GO:0018193 336 0.011
nad metabolic process GO:0019674 7 0.011
connective tissue development GO:0061448 179 0.011
positive regulation of nervous system development GO:0051962 221 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
oxidoreduction coenzyme metabolic process GO:0006733 16 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
muscle tissue development GO:0060537 308 0.011
positive regulation of cell development GO:0010720 237 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
carbohydrate homeostasis GO:0033500 128 0.011
regulation of cytokine production GO:0001817 266 0.011
liver development GO:0001889 66 0.011
regulation of endopeptidase activity GO:0052548 89 0.011
mitochondrial fusion GO:0008053 9 0.011
response to superoxide GO:0000303 16 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
trna aminoacylation GO:0043039 1 0.011
innate immune response GO:0045087 157 0.011
regulation of peptidase activity GO:0052547 96 0.011
regulation of translation GO:0006417 71 0.011
lateral inhibition GO:0046331 1 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
negative regulation of protein metabolic process GO:0051248 282 0.010
age dependent response to oxidative stress GO:0001306 3 0.010
cellular response to peptide GO:1901653 92 0.010
regulation of blood pressure GO:0008217 93 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
oxidative phosphorylation GO:0006119 14 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
regulation of ion transport GO:0043269 215 0.010
positive regulation of kinase activity GO:0033674 155 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
mitochondrial transport GO:0006839 36 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
membrane organization GO:0061024 245 0.010
excretion GO:0007588 22 0.010
positive regulation of mitochondrion organization GO:0010822 17 0.010
insulin secretion GO:0030073 89 0.010

Gfm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.034
disease of anatomical entity DOID:7 0 0.034
hematopoietic system disease DOID:74 0 0.034
central nervous system disease DOID:331 0 0.031
nervous system disease DOID:863 0 0.031
neurodegenerative disease DOID:1289 0 0.028
disease of metabolism DOID:0014667 0 0.018
amino acid metabolic disorder DOID:9252 0 0.018
inherited metabolic disorder DOID:655 0 0.018
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
hemorrhagic disease DOID:2213 0 0.012
blood coagulation disease DOID:1247 0 0.012