Mus musculus

182 known processes

Gja1

gap junction protein, alpha 1

(Aliases: AU042049,AW546267,Cx43,Cnx43,Cx43alpha1,Npm1,connexin43,Gja-1)

Gja1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle tissue development GO:0060537 308 0.994
axon guidance GO:0007411 141 0.972
regionalization GO:0003002 337 0.950
cardiac muscle cell contraction GO:0086003 7 0.938
epithelial tube morphogenesis GO:0060562 303 0.929
regulation of heart contraction GO:0008016 77 0.922
regulation of ion transport GO:0043269 215 0.921
striated muscle tissue development GO:0014706 293 0.917
embryonic organ morphogenesis GO:0048562 276 0.917
muscle contraction GO:0006936 101 0.903
skin development GO:0043588 220 0.892
embryonic skeletal system development GO:0048706 120 0.885
Zebrafish
axonogenesis GO:0007409 274 0.880
amine metabolic process GO:0009308 45 0.873
cardiac muscle tissue development GO:0048738 130 0.870
Mouse Rat
regulation of cardiac muscle contraction GO:0055117 21 0.839
Mouse
cell fate commitment GO:0045165 210 0.834
myosin filament organization GO:0031033 3 0.832
organelle assembly GO:0070925 177 0.825
chemotaxis GO:0006935 247 0.821
skeletal muscle organ development GO:0060538 163 0.818
anatomical structure homeostasis GO:0060249 145 0.811
metanephric glomerular mesangium development GO:0072223 3 0.809
positive regulation of growth GO:0045927 104 0.802
multicellular organismal signaling GO:0035637 91 0.798
intrinsic apoptotic signaling pathway in response to osmotic stress GO:0008627 2 0.792
regulation of homeostatic process GO:0032844 182 0.786
ventricular cardiac muscle cell action potential GO:0086005 4 0.784
Mouse
stem cell differentiation GO:0048863 268 0.779
striated muscle contraction GO:0006941 45 0.778
negative regulation of molecular function GO:0044092 258 0.764
appendage morphogenesis GO:0035107 149 0.764
actin filament based movement GO:0030048 23 0.757
neuron projection guidance GO:0097485 141 0.750
camera type eye development GO:0043010 266 0.736
cardiocyte differentiation GO:0035051 87 0.735
formation of radial glial scaffolds GO:0021943 4 0.727
cardiac muscle tissue morphogenesis GO:0055008 44 0.715
cellular amine metabolic process GO:0044106 44 0.705
regulation of muscle tissue development GO:1901861 97 0.690
regulation of cellular amine metabolic process GO:0033238 20 0.679
activation of mapk activity involved in innate immune response GO:0035419 2 0.672
intraciliary retrograde transport GO:0035721 3 0.668
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.665
myofibril assembly GO:0030239 34 0.662
cell adhesion GO:0007155 329 0.657
cellular amino acid metabolic process GO:0006520 103 0.654
spermatid differentiation GO:0048515 115 0.653
positive regulation of cell death GO:0010942 224 0.636
oocyte axis specification GO:0007309 2 0.629
cardiac muscle cell development GO:0055013 39 0.623
regulation of actin filament based process GO:0032970 99 0.612
Mouse
apoptotic signaling pathway GO:0097190 306 0.601
regulation of cellular ketone metabolic process GO:0010565 66 0.597
organonitrogen compound catabolic process GO:1901565 264 0.597
cardiac muscle cell action potential GO:0086001 11 0.593
Mouse
regulation of muscle system process GO:0090257 80 0.593
Mouse
regulation of blood circulation GO:1903522 93 0.589
muscle cell development GO:0055001 133 0.588
regulation of cell cycle GO:0051726 281 0.585
salivary gland morphogenesis GO:0007435 33 0.580
cellular component assembly involved in morphogenesis GO:0010927 139 0.578
negative regulation of cell proliferation GO:0008285 296 0.572
Rat
limb development GO:0060173 166 0.567
ear development GO:0043583 200 0.566
Mouse
maintenance of location GO:0051235 89 0.564
spermatid development GO:0007286 108 0.560
stem cell development GO:0048864 219 0.558
ribonucleoside metabolic process GO:0009119 245 0.557
synaptic transmission GO:0007268 329 0.557
Mouse
negative regulation of apoptotic signaling pathway GO:2001234 104 0.557
regulation of kinase activity GO:0043549 249 0.556
protein localization to membrane GO:0072657 108 0.541
ion transmembrane transport GO:0034220 361 0.541
regulation of striated muscle cell differentiation GO:0051153 81 0.534
oocyte construction GO:0007308 2 0.527
regulation of membrane depolarization GO:0003254 11 0.527
peptidyl serine modification GO:0018209 83 0.517
homeostasis of number of cells GO:0048872 210 0.517
wound healing GO:0042060 157 0.511
mesonephric tubule development GO:0072164 94 0.511
positive regulation of cardioblast differentiation GO:0051891 3 0.511
gliogenesis GO:0042063 141 0.510
regulation of cellular amino acid metabolic process GO:0006521 5 0.509
epidermis development GO:0008544 187 0.506
heart contraction GO:0060047 93 0.505
hair follicle morphogenesis GO:0031069 29 0.505
gonad development GO:0008406 141 0.502
odontogenesis GO:0042476 78 0.501
regulation of leukocyte differentiation GO:1902105 159 0.498
embryonic skeletal system morphogenesis GO:0048704 91 0.495
Zebrafish
regulation of muscle contraction GO:0006937 49 0.482
Mouse
calcium ion transport GO:0006816 159 0.482
Rat
cellular response to organic cyclic compound GO:0071407 87 0.470
muscle tissue morphogenesis GO:0060415 53 0.466
lung development GO:0030324 164 0.463
positive regulation of cellular amine metabolic process GO:0033240 5 0.457
limb morphogenesis GO:0035108 149 0.457
vascular process in circulatory system GO:0003018 62 0.453
Mouse Rat
septum primum development GO:0003284 4 0.452
Mouse
organ growth GO:0035265 117 0.449
Mouse Rat
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.446
regulation of apoptotic signaling pathway GO:2001233 197 0.445
positive regulation of eosinophil migration GO:2000418 2 0.444
positive regulation of epithelial cell proliferation GO:0050679 68 0.440
positive regulation of epithelial to mesenchymal transition GO:0010718 13 0.434
circulatory system process GO:0003013 197 0.425
response to oxygen levels GO:0070482 62 0.425
purine nucleoside metabolic process GO:0042278 241 0.424
blood circulation GO:0008015 195 0.424
embryonic appendage morphogenesis GO:0035113 126 0.424
digestive tract morphogenesis GO:0048546 147 0.417
myeloid cell homeostasis GO:0002262 114 0.415
regulation of ion homeostasis GO:2000021 64 0.410
mechanoreceptor differentiation GO:0042490 67 0.409
substrate dependent cell migration GO:0006929 18 0.406
heart morphogenesis GO:0003007 178 0.404
germ cell development GO:0007281 185 0.404
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.403
urogenital system development GO:0001655 261 0.398
meiotic cell cycle GO:0051321 122 0.391
skeletal system morphogenesis GO:0048705 203 0.385
Zebrafish
regulation of ossification GO:0030278 112 0.385
gland development GO:0048732 330 0.384
negative regulation of protein metabolic process GO:0051248 282 0.384
negative regulation of striated muscle cell differentiation GO:0051154 14 0.383
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.379
branching morphogenesis of an epithelial tube GO:0048754 159 0.377
skeletal muscle fiber development GO:0048741 58 0.374
muscle cell differentiation GO:0042692 261 0.365
cardiac right ventricle formation GO:0003219 3 0.365
development of primary sexual characteristics GO:0045137 143 0.363
cell type specific apoptotic process GO:0097285 268 0.362
ear morphogenesis GO:0042471 118 0.359
Mouse
appendage development GO:0048736 166 0.359
neuronal action potential GO:0019228 54 0.357
Mouse
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.356
cation transport GO:0006812 399 0.353
Rat
atrial ventricular junction remodeling GO:0003294 2 0.351
cardiac conduction GO:0061337 17 0.349
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.348
leukocyte differentiation GO:0002521 342 0.347
cardiac ventricle development GO:0003231 83 0.347
Mouse
renal tubule development GO:0061326 87 0.346
cardioblast migration to the midline involved in heart field formation GO:0060975 1 0.345
positive regulation of map kinase activity GO:0043406 84 0.343
positive regulation of apoptotic signaling pathway GO:2001235 95 0.336
mitral valve morphogenesis GO:0003183 4 0.334
regulation of heart rate GO:0002027 36 0.332
Mouse
carbohydrate homeostasis GO:0033500 128 0.331
respiratory system development GO:0060541 190 0.328
regulation of neuron differentiation GO:0045664 281 0.327
inflammatory response GO:0006954 244 0.326
Rat
positive regulation of glial cell differentiation GO:0045687 21 0.325
positive regulation of cell development GO:0010720 237 0.324
germ line stem cell division GO:0042078 2 0.323
telencephalon development GO:0021537 186 0.321
nuclear division GO:0000280 158 0.320
cell communication involved in cardiac conduction GO:0086065 9 0.318
Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.318
negative regulation of cell cycle GO:0045786 123 0.315
striated muscle cell development GO:0055002 125 0.313
regulation of striated muscle contraction GO:0006942 25 0.313
Mouse
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.312
membrane organization GO:0061024 245 0.310
peptidyl amino acid modification GO:0018193 336 0.309
renal tubule morphogenesis GO:0061333 72 0.307
peptidyl serine phosphorylation GO:0018105 74 0.306
cellular ketone metabolic process GO:0042180 84 0.304
myosin filament assembly GO:0031034 2 0.304
microtubule cytoskeleton organization GO:0000226 157 0.303
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.303
Mouse
epithelial cell proliferation GO:0050673 174 0.298
Rat
megakaryocyte differentiation GO:0030219 26 0.296
retinal bipolar neuron differentiation GO:0060040 5 0.293
bone resorption GO:0045453 38 0.293
tendon cell differentiation GO:0035990 4 0.292
cation homeostasis GO:0055080 212 0.290
Rat
dna metabolic process GO:0006259 303 0.290
Rat
mast cell differentiation GO:0060374 5 0.289
blood vessel morphogenesis GO:0048514 285 0.288
cellular response to growth factor stimulus GO:0071363 197 0.288
positive regulation of cell migration GO:0030335 109 0.282
single organismal cell cell adhesion GO:0016337 131 0.281
metal ion homeostasis GO:0055065 189 0.280
Rat
positive regulation of osteoblast differentiation GO:0045669 34 0.280
cellular response to abiotic stimulus GO:0071214 56 0.277
Rat
ventricular septum morphogenesis GO:0060412 27 0.276
Mouse
positive regulation of programmed cell death GO:0043068 218 0.275
lymphocyte differentiation GO:0030098 242 0.275
regulation of cellular component biogenesis GO:0044087 181 0.273
Rat
transmembrane transport GO:0055085 412 0.271
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.271
regulation of membrane potential GO:0042391 192 0.270
jak stat cascade GO:0007259 42 0.269
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.268
ras protein signal transduction GO:0007265 77 0.267
small gtpase mediated signal transduction GO:0007264 97 0.267
mammary gland epithelium development GO:0061180 65 0.266
striated muscle myosin thick filament assembly GO:0071688 1 0.266
regulation of anatomical structure size GO:0090066 178 0.266
Mouse Rat
plasma membrane organization GO:0007009 90 0.265
epithelial to mesenchymal transition GO:0001837 47 0.265
odontogenesis of dentin containing tooth GO:0042475 66 0.263
regulation of protein transport GO:0051223 163 0.263
Mouse
cell division GO:0051301 120 0.263
response to organic cyclic compound GO:0014070 198 0.262
male gamete generation GO:0048232 285 0.260
endomembrane system organization GO:0010256 147 0.259
glycosyl compound catabolic process GO:1901658 206 0.259
glycosyl compound metabolic process GO:1901657 246 0.258
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.258
embryonic heart tube morphogenesis GO:0003143 51 0.257
dendrite development GO:0016358 115 0.256
neuron migration GO:0001764 122 0.256
cytokine production GO:0001816 319 0.255
forebrain development GO:0030900 302 0.255
positive regulation of p38mapk cascade GO:1900745 1 0.254
regulation of ryanodine sensitive calcium release channel activity GO:0060314 10 0.253
t cell activation GO:0042110 289 0.253
embryonic heart tube anterior posterior pattern specification GO:0035054 3 0.252
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.249
purine nucleobase biosynthetic process GO:0009113 3 0.249
lymphocyte proliferation GO:0046651 164 0.249
regulation of cardiac muscle cell contraction GO:0086004 11 0.248
Mouse
glomerulus development GO:0032835 40 0.247
synapse organization GO:0050808 125 0.245
Mouse
regulation of establishment of protein localization GO:0070201 181 0.245
Mouse
cardiac myofibril assembly GO:0055003 12 0.245
ameboidal type cell migration GO:0001667 128 0.242
retina development in camera type eye GO:0060041 119 0.242
cellular calcium ion homeostasis GO:0006874 119 0.242
Rat
chromatin organization GO:0006325 206 0.239
nephron development GO:0072006 109 0.239
purine ribonucleotide metabolic process GO:0009150 290 0.238
regulation of epithelial to mesenchymal transition GO:0010717 22 0.238
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.238
glial cell differentiation GO:0010001 131 0.238
regulation of ion transmembrane transport GO:0034765 119 0.237
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.236
transmission of nerve impulse GO:0019226 76 0.234
Mouse
myelination in peripheral nervous system GO:0022011 19 0.233
regulation of cell adhesion GO:0030155 154 0.233
regulation of cell projection organization GO:0031344 206 0.231
negative regulation of epidermis development GO:0045683 9 0.230
positive regulation of thymocyte migration GO:2000412 2 0.227
myeloid leukocyte differentiation GO:0002573 119 0.226
organophosphate catabolic process GO:0046434 232 0.226
mesenchyme development GO:0060485 152 0.226
regulation of bone remodeling GO:0046850 28 0.225
body morphogenesis GO:0010171 45 0.225
positive regulation of neuron differentiation GO:0045666 141 0.225
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 9 0.225
cardiac muscle tissue growth GO:0055017 37 0.225
Rat
positive regulation of bmp signaling pathway GO:0030513 23 0.223
regulation of mapk cascade GO:0043408 248 0.220
positive regulation of bone remodeling GO:0046852 13 0.218
molting cycle GO:0042303 90 0.217
carbon catabolite activation of transcription GO:0045991 4 0.216
chondrocyte differentiation GO:0002062 72 0.216
regulation of transferase activity GO:0051338 263 0.215
coronary vasculature development GO:0060976 12 0.215
oxidation reduction process GO:0055114 342 0.214
endodermal cell fate commitment GO:0001711 12 0.212
hair follicle development GO:0001942 85 0.211
actomyosin structure organization GO:0031032 56 0.207
positive regulation of protein transport GO:0051222 93 0.207
regulation of binding GO:0051098 111 0.207
negative regulation of anoikis GO:2000811 2 0.206
smoothened signaling pathway GO:0007224 105 0.206
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.206
cellular response to osmotic stress GO:0071470 7 0.206
retina vasculature development in camera type eye GO:0061298 17 0.205
regulation of map kinase activity GO:0043405 120 0.205
hair cycle GO:0042633 90 0.205
negative regulation of binding GO:0051100 39 0.204
tendon formation GO:0035992 4 0.204
neural crest cell migration GO:0001755 32 0.203
bmp signaling pathway GO:0030509 93 0.202
regulation of organelle organization GO:0033043 289 0.201
segmentation GO:0035282 93 0.200
negative regulation of cardiac muscle tissue development GO:0055026 8 0.199
Rat
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.199
ribonucleoside monophosphate catabolic process GO:0009158 57 0.199
heart valve development GO:0003170 23 0.199
pyramidal neuron migration GO:0021852 1 0.198
digestive system development GO:0055123 200 0.198
substrate dependent cell migration cell extension GO:0006930 4 0.197
inorganic cation transmembrane transport GO:0098662 207 0.197
organelle localization GO:0051640 179 0.197
nucleoside metabolic process GO:0009116 246 0.196
positive regulation of axon extension GO:0045773 20 0.196
regulation of cardioblast differentiation GO:0051890 3 0.195
clara cell differentiation GO:0060486 4 0.195
positive regulation of creb transcription factor activity GO:0032793 4 0.195
skeletal system development GO:0001501 356 0.193
Zebrafish Mouse
regulation of eosinophil migration GO:2000416 2 0.192
nephron morphogenesis GO:0072028 69 0.192
negative regulation of mitotic cell cycle GO:0045930 58 0.192
cytoplasmic transport GO:0016482 234 0.190
cerebral cortex cell migration GO:0021795 44 0.190
action potential GO:0001508 78 0.189
Mouse
response to transforming growth factor beta GO:0071559 88 0.189
regulation of mitotic cell cycle GO:0007346 126 0.188
ribonucleotide catabolic process GO:0009261 208 0.188
inner ear receptor cell differentiation GO:0060113 61 0.187
regulation of jak stat cascade GO:0046425 34 0.186
negative regulation of epithelial cell proliferation GO:0050680 64 0.186
Rat
positive regulation of cell proliferation involved in heart valve morphogenesis GO:0003251 1 0.186
digestive tract development GO:0048565 190 0.186
response to extracellular stimulus GO:0009991 127 0.185
sensory perception GO:0007600 245 0.185
Mouse
ossification GO:0001503 216 0.185
cardiac epithelial to mesenchymal transition GO:0060317 18 0.184
endodermal cell fate specification GO:0001714 4 0.184
actin cytoskeleton reorganization GO:0031532 21 0.183
nucleocytoplasmic transport GO:0006913 139 0.182
establishment of neuroblast polarity GO:0045200 1 0.181
negative regulation of hydrolase activity GO:0051346 71 0.181
regulation of cell motility GO:2000145 236 0.181
axon ensheathment GO:0008366 76 0.180
Mouse
cell migration involved in coronary angiogenesis GO:0060981 1 0.179
regulation of protein targeting GO:1903533 61 0.179
head morphogenesis GO:0060323 34 0.179
signal transduction in absence of ligand GO:0038034 55 0.178
cardiac cell development GO:0055006 41 0.177
regulation of cytoplasmic transport GO:1903649 112 0.176
response to corticosteroid GO:0031960 20 0.175
extracellular structure organization GO:0043062 148 0.175
locomotory behavior GO:0007626 195 0.175
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.175
response to drug GO:0042493 75 0.175
epithelial cell development GO:0002064 159 0.174
lipid localization GO:0010876 126 0.174
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.174
associative learning GO:0008306 61 0.173
positive regulation of protein kinase activity GO:0045860 144 0.173
ventricular cardiac muscle cell development GO:0055015 11 0.172
negative regulation of immature t cell proliferation GO:0033087 3 0.172
bone development GO:0060348 120 0.172
spermatogenesis GO:0007283 284 0.172
morphogenesis of embryonic epithelium GO:0016331 159 0.170
cell migration involved in gastrulation GO:0042074 13 0.170
regulation of tissue remodeling GO:0034103 38 0.168
cardiac muscle contraction GO:0060048 32 0.167
regulation of lymphocyte differentiation GO:0045619 107 0.167
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.167
response to metal ion GO:0010038 47 0.166
kidney development GO:0001822 213 0.165
muscle cell fate specification GO:0042694 1 0.165
pallium development GO:0021543 120 0.165
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.164
cell cycle arrest GO:0007050 37 0.164
multicellular organism growth GO:0035264 161 0.164
cardiac chamber development GO:0003205 108 0.164
Mouse
kidney epithelium development GO:0072073 121 0.163
regulation of secretion GO:0051046 274 0.163
Mouse Rat
cellular homeostasis GO:0019725 240 0.161
Rat
purine ribonucleoside metabolic process GO:0046128 241 0.161
localization within membrane GO:0051668 4 0.160
purine nucleotide catabolic process GO:0006195 211 0.160
positive regulation of cell adhesion GO:0045785 80 0.160
purine ribonucleotide catabolic process GO:0009154 208 0.159
extracellular matrix dependent thymocyte migration GO:0072680 1 0.159
nucleotide catabolic process GO:0009166 217 0.159
ribonucleoside catabolic process GO:0042454 206 0.157
regulation of p38mapk cascade GO:1900744 3 0.157
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.157
cerebellum development GO:0021549 77 0.156
embryonic olfactory bulb interneuron precursor migration GO:0021831 2 0.156
compound eye development GO:0048749 1 0.155
glycerolipid metabolic process GO:0046486 122 0.154
morphogenesis of a polarized epithelium GO:0001738 37 0.153
mitotic cell cycle GO:0000278 195 0.153
establishment of protein localization to membrane GO:0090150 54 0.153
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.152
neuron apoptotic process GO:0051402 142 0.152
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.151
positive regulation of apoptotic process GO:0043065 217 0.151
bone morphogenesis GO:0060349 78 0.151
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.151
mesoderm morphogenesis GO:0048332 64 0.150
nucleus localization GO:0051647 20 0.150
megakaryocyte development GO:0035855 15 0.150
g protein coupled receptor signaling pathway GO:0007186 243 0.148
nephron tubule development GO:0072080 84 0.148
oocyte differentiation GO:0009994 35 0.148
embryonic placenta development GO:0001892 98 0.147
Mouse
purine nucleotide metabolic process GO:0006163 302 0.146
cardioblast migration GO:0003260 1 0.146
cardiac endothelial cell differentiation GO:0003348 4 0.145
neural tube development GO:0021915 160 0.144
somitogenesis GO:0001756 69 0.144
positive regulation of nervous system development GO:0051962 221 0.144
protein localization to organelle GO:0033365 185 0.143
asymmetric neuroblast division GO:0055059 1 0.143
renal system development GO:0072001 225 0.143
av node cell to bundle of his cell communication GO:0086067 2 0.143
Mouse
eosinophil migration GO:0072677 3 0.142
regulation of response to wounding GO:1903034 189 0.142
Mouse Rat
regulation of erk1 and erk2 cascade GO:0070372 71 0.141
regulation of transmembrane transport GO:0034762 128 0.140
angiogenesis involved in coronary vascular morphogenesis GO:0060978 2 0.140
nephron epithelium morphogenesis GO:0072088 68 0.140
cell cell adhesion GO:0098609 41 0.139
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.139
regulation of epithelial cell proliferation GO:0050678 141 0.139
Rat
glial cell development GO:0021782 54 0.138
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.138
metencephalon development GO:0022037 89 0.138
salivary gland development GO:0007431 37 0.137
glucose homeostasis GO:0042593 128 0.137
cardiac ventricle morphogenesis GO:0003208 50 0.136
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.136
neural tube closure GO:0001843 90 0.136
membrane depolarization during sa node cell action potential GO:0086046 2 0.135
positive regulation of smooth muscle cell migration GO:0014911 4 0.134
trachea formation GO:0060440 3 0.134
intrinsic apoptotic signaling pathway GO:0097193 132 0.134
rna stabilization GO:0043489 9 0.134
sensory perception of mechanical stimulus GO:0050954 107 0.132
Mouse
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.132
positive regulation of neuron projection development GO:0010976 79 0.131
somite development GO:0061053 81 0.131
organic hydroxy compound metabolic process GO:1901615 203 0.131
actin mediated cell contraction GO:0070252 15 0.130
establishment of protein localization to organelle GO:0072594 118 0.130
regulation of cell shape GO:0008360 39 0.129
heart field specification GO:0003128 6 0.129
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.129
regulation of bone resorption GO:0045124 24 0.128
morphogenesis of a branching structure GO:0001763 203 0.127
tolerance induction to self antigen GO:0002513 4 0.126
regulation of reactive oxygen species metabolic process GO:2000377 40 0.126
morphogenesis of a branching epithelium GO:0061138 193 0.126
regulation of myeloid cell differentiation GO:0045637 96 0.126
tricuspid valve development GO:0003175 3 0.126
divalent metal ion transport GO:0070838 172 0.125
Rat
angiogenesis GO:0001525 201 0.125
learning or memory GO:0007611 148 0.125
p38mapk cascade GO:0038066 4 0.125
microtubule based process GO:0007017 236 0.124
regulation of biomineral tissue development GO:0070167 33 0.124
midgut development GO:0007494 4 0.124
multicellular organismal homeostasis GO:0048871 164 0.123
respiratory tube development GO:0030323 167 0.123
positive regulation of hydrolase activity GO:0051345 148 0.123
nucleoside phosphate metabolic process GO:0006753 338 0.123
positive regulation of leukocyte differentiation GO:1902107 86 0.123
cell proliferation in hindbrain GO:0021534 10 0.123
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.122
atrioventricular valve morphogenesis GO:0003181 13 0.122
blastocyst development GO:0001824 80 0.122
lateral mesodermal cell differentiation GO:0048371 3 0.121
cytoskeleton dependent intracellular transport GO:0030705 50 0.121
purine ribonucleoside catabolic process GO:0046130 205 0.121
hematopoietic progenitor cell differentiation GO:0002244 143 0.121
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.121
regulation of mast cell differentiation GO:0060375 3 0.120
negative regulation of muscle cell differentiation GO:0051148 33 0.120
srebp signaling pathway GO:0032933 4 0.120
mesonephric epithelium development GO:0072163 94 0.119
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.119
negative regulation of cellular amine metabolic process GO:0033239 1 0.119
regulation of intracellular transport GO:0032386 159 0.119
regulation of chromosome organization GO:0033044 83 0.119
sensory perception of light stimulus GO:0050953 54 0.118
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.118
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.118
ventricular cardiac muscle cell differentiation GO:0055012 17 0.118
stem cell proliferation GO:0072089 117 0.117
cation transmembrane transport GO:0098655 266 0.117
globus pallidus development GO:0021759 2 0.117
carbon catabolite regulation of transcription GO:0045990 4 0.117
regulation of cell migration GO:0030334 219 0.117
organic cyclic compound catabolic process GO:1901361 295 0.117
fat cell differentiation GO:0045444 160 0.116
response to purine containing compound GO:0014074 28 0.116
negative regulation of t cell proliferation GO:0042130 38 0.116
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.115

Gja1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 0 0.990
Human
disease of anatomical entity DOID:7 0 0.990
Human
cardiovascular system disease DOID:1287 0 0.990
Human
myopathy DOID:423 0 0.970
muscular disease DOID:0080000 0 0.970
cardiomyopathy DOID:0050700 0 0.970
musculoskeletal system disease DOID:17 0 0.970
Human
muscle tissue disease DOID:66 0 0.970
intrinsic cardiomyopathy DOID:0060036 0 0.865
connective tissue disease DOID:65 0 0.518
Human
cancer DOID:162 0 0.291
disease of cellular proliferation DOID:14566 0 0.291
disease of metabolism DOID:0014667 0 0.203
bone remodeling disease DOID:0080005 0 0.168
Human
bone disease DOID:0080001 0 0.168
Human
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.141