|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.668
|
|
|
|
cholesterol homeostasis
|
GO:0042632 |
44 |
0.635
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.561
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.477
|
Mouse |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.453
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.449
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.424
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.342
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.326
|
Mouse |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.308
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.291
|
Mouse |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.276
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.271
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.255
|
Fly |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.255
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.245
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.242
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.238
|
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.237
|
Fly |
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.237
|
Mouse |
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.233
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.229
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.229
|
Mouse |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.227
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.210
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.207
|
Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.202
|
|
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.201
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.199
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.197
|
Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.194
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.190
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.189
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.187
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.187
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.185
|
Mouse |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.184
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.183
|
Mouse |
|
|
forebrain development
|
GO:0030900 |
302 |
0.178
|
Mouse |
|
|
urogenital system development
|
GO:0001655 |
261 |
0.177
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.173
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.172
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.168
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.161
|
Mouse Fly |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.161
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.160
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.160
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.158
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.156
|
Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.155
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.154
|
Mouse |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.149
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.145
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.141
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.140
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.140
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.138
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.137
|
Mouse Fly |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.137
|
Mouse |
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.134
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.134
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.131
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.130
|
Mouse |
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.127
|
Mouse |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.126
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.125
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.125
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.125
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.124
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.123
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.121
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.115
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.115
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.115
|
|
|
|
sterol homeostasis
|
GO:0055092 |
45 |
0.114
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.113
|
Mouse Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.112
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.111
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.109
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.108
|
Fly |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.108
|
Worm |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.107
|
Mouse |
|
|
maintenance of location
|
GO:0051235 |
89 |
0.107
|
|
|
|
sensory perception of umami taste
|
GO:0050917 |
4 |
0.107
|
Mouse |
|
|
gland development
|
GO:0048732 |
330 |
0.106
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.105
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.104
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.104
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.102
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.101
|
Worm |
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.101
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.100
|
Mouse |
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.100
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.099
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.099
|
Fly |
|
|
rhodopsin mediated signaling pathway
|
GO:0016056 |
4 |
0.098
|
Fly |
|
|
regulation of tor signaling
|
GO:0032006 |
17 |
0.098
|
Mouse |
|
|
neural tube development
|
GO:0021915 |
160 |
0.097
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.097
|
|
|
|
regulation of fatty acid metabolic process
|
GO:0019217 |
28 |
0.096
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.096
|
Mouse |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.096
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.095
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.095
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.095
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.094
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.094
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.094
|
Mouse |
|
|
acetylcholine transport
|
GO:0015870 |
2 |
0.093
|
Worm |
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.091
|
Mouse |
|
|
g protein coupled acetylcholine receptor signaling pathway
|
GO:0007213 |
4 |
0.091
|
Mouse |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.090
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.090
|
Worm |
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.090
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.089
|
Mouse |
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.086
|
Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.085
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.085
|
Mouse |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.084
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.084
|
Fly |
|
|
lipid catabolic process
|
GO:0016042 |
69 |
0.084
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.083
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.083
|
Mouse Fly |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.083
|
Mouse |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.083
|
Mouse |
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.083
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.082
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.082
|
Mouse |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.082
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.081
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
26 |
0.081
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.081
|
Mouse |
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.080
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.080
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.080
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.080
|
Mouse Fly |
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.079
|
Mouse |
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.079
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.079
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.078
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.078
|
Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.078
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.078
|
Mouse |
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.077
|
Mouse |
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.077
|
Mouse |
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.076
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.076
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.076
|
Mouse |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.076
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.076
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.075
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.075
|
Fly |
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.074
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.074
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.074
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.073
|
Mouse Fly |
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.073
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.073
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.073
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.072
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.072
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.072
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.072
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.072
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.071
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.071
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
60 |
0.071
|
Mouse Fly |
|
|
neutral lipid metabolic process
|
GO:0006638 |
57 |
0.071
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.070
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.070
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.069
|
Mouse |
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.069
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.069
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.069
|
Mouse |
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.068
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.068
|
Mouse |
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.068
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.068
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.068
|
Mouse |
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.068
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.067
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.067
|
Mouse |
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.067
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.067
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.066
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.066
|
Mouse |
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.066
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.066
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.066
|
Mouse Fly |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.066
|
Mouse |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.066
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.066
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.066
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.065
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.065
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.064
|
Mouse |
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.064
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.064
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.064
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.064
|
Mouse |
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.064
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.064
|
|
|
|
translation
|
GO:0006412 |
93 |
0.063
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.063
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.062
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.062
|
Fly |
|
|
negative regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042524 |
2 |
0.061
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
42 |
0.060
|
Mouse |
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.060
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.060
|
Mouse |
|
|
placenta development
|
GO:0001890 |
140 |
0.060
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.059
|
Mouse |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.059
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.059
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.058
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.058
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.058
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.058
|
Mouse Fly |
|
|
endochondral bone morphogenesis
|
GO:0060350 |
50 |
0.058
|
Mouse |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.057
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.057
|
Mouse |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.057
|
Mouse Fly |
|
|
organelle fission
|
GO:0048285 |
170 |
0.057
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.057
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.056
|
Mouse |
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.056
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.056
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.056
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.056
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.055
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.055
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.055
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.055
|
|
|
|
localization within membrane
|
GO:0051668 |
4 |
0.055
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.055
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.054
|
Mouse |
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
46 |
0.054
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.054
|
Worm |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.054
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.054
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.054
|
Mouse |
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.054
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.053
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.053
|
Mouse |
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.053
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.053
|
Mouse |
|
|
cellular response to light stimulus
|
GO:0071482 |
19 |
0.052
|
Fly |
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.052
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.052
|
Mouse |
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.051
|
Mouse |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.051
|
Mouse |
|
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.051
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.051
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.051
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.051
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.051
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.051
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.050
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.050
|
Mouse Worm |
|
|
peptide secretion
|
GO:0002790 |
114 |
0.050
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.050
|
Worm |
|
|
gonad development
|
GO:0008406 |
141 |
0.050
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.049
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.049
|
Mouse |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.049
|
Mouse |
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.049
|
|
|
|
proteoglycan biosynthetic process
|
GO:0030166 |
20 |
0.049
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.048
|
Mouse |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.048
|
|
|
|
regulation of acetylcholine secretion neurotransmission
|
GO:0014056 |
2 |
0.048
|
Worm |
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.048
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.048
|
Mouse |
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.048
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.048
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.048
|
Fly |
|
|
rhythmic process
|
GO:0048511 |
174 |
0.047
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.047
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.047
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.047
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.047
|
Mouse |
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.047
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.047
|
Mouse |
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.047
|
Mouse |
|
|
heart process
|
GO:0003015 |
94 |
0.047
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.047
|
Mouse |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.046
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.046
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.046
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.046
|
Mouse |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.046
|
Mouse Fly |
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.045
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.045
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.045
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.045
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.045
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.044
|
Fly |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.044
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.044
|
Mouse |
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.044
|
Mouse |
|
|
pigmentation
|
GO:0043473 |
71 |
0.044
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.043
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.043
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.043
|
Fly |
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.043
|
Mouse |
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.043
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.043
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.043
|
Mouse |
|
|
detection of external stimulus
|
GO:0009581 |
61 |
0.043
|
Mouse Fly |
|
|
protein homooligomerization
|
GO:0051260 |
43 |
0.043
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.043
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.042
|
Mouse Fly |
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.042
|
Mouse |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.042
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.041
|
Mouse |
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.041
|
Mouse |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.041
|
Mouse |
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.041
|
Mouse Fly |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.041
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.041
|
Mouse Fly |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.041
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.041
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.041
|
Fly |
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.040
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.040
|
|
|
|
positive regulation of fatty acid oxidation
|
GO:0046321 |
4 |
0.040
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.040
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.040
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.040
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.040
|
Worm |
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.039
|
Mouse |
|
|
response to drug
|
GO:0042493 |
75 |
0.039
|
Mouse |
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.039
|
|
|
|
cell cycle arrest
|
GO:0007050 |
37 |
0.039
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.039
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.039
|
Worm |
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.039
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.038
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.038
|
|
|
|
camera type eye photoreceptor cell differentiation
|
GO:0060219 |
15 |
0.038
|
Mouse |
|
|
developmental maturation
|
GO:0021700 |
193 |
0.038
|
Mouse |
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.038
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.038
|
Mouse |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.038
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.038
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.038
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.038
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.038
|
Mouse |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.038
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.037
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.037
|
|
|
|
positive regulation of steroid biosynthetic process
|
GO:0010893 |
4 |
0.037
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.037
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.037
|
|
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.037
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.036
|
Mouse |
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.036
|
Fly |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.036
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.036
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.036
|
Mouse |
|
|
chromatin modification
|
GO:0016568 |
187 |
0.036
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.035
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.035
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
38 |
0.035
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.035
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.035
|
Mouse |
|
|
p38mapk cascade
|
GO:0038066 |
4 |
0.035
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.035
|
Mouse Fly |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.034
|
Mouse Fly |
|
|
acetylcholine secretion neurotransmission
|
GO:0014055 |
2 |
0.034
|
Worm |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.034
|
|
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
26 |
0.034
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.034
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.034
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
14 |
0.034
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.034
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.034
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.034
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.034
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.034
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.033
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.033
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.033
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.033
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.033
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.033
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.033
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.033
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.033
|
Mouse Fly |
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
30 |
0.032
|
Mouse |
|
|
chromatin organization
|
GO:0006325 |
206 |
0.032
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.032
|
Mouse |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.032
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.032
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.032
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.032
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.032
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.032
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.032
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.032
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
34 |
0.031
|
Mouse |
|
|
myotube cell development
|
GO:0014904 |
60 |
0.031
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.031
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.031
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.031
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.031
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.031
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.030
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.030
|
Mouse |
|
|
ossification
|
GO:0001503 |
216 |
0.030
|
Mouse |
|
|
methylation
|
GO:0032259 |
134 |
0.030
|
Mouse |
|
|
regulation of cholesterol homeostasis
|
GO:2000188 |
9 |
0.030
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.030
|
Mouse Worm |
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.030
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.030
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.030
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.030
|
|
|
|
lactation
|
GO:0007595 |
25 |
0.030
|
|
|
|
mammary gland epithelial cell proliferation
|
GO:0033598 |
24 |
0.030
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.030
|
Mouse Fly |
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.029
|
|
|
|
sensory system development
|
GO:0048880 |
3 |
0.029
|
|
|
|
regulation of glutamine family amino acid metabolic process
|
GO:0000820 |
1 |
0.029
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.029
|
Worm |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.029
|
Mouse Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.029
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.029
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.029
|
Mouse Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.029
|
Mouse Fly |
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.029
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.029
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.029
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.028
|
Mouse |
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.028
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.028
|
|
|
|
type i pneumocyte differentiation
|
GO:0060509 |
7 |
0.028
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.028
|
Mouse Fly |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.028
|
Mouse Fly |
|
|
acylglycerol metabolic process
|
GO:0006639 |
55 |
0.028
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.028
|
Mouse |
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.028
|
Mouse |
|
|
triglyceride homeostasis
|
GO:0070328 |
15 |
0.027
|
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.027
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.027
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.027
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.027
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.027
|
Mouse |
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.027
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.027
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.027
|
Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.027
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.027
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.027
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
47 |
0.027
|
|
|
|
response to cold
|
GO:0009409 |
19 |
0.027
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.027
|
Mouse Fly |
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.027
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.027
|
Mouse |
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.027
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.027
|
Mouse Fly |
|
|
fatty acid transmembrane transport
|
GO:1902001 |
1 |
0.027
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.027
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.027
|
Mouse Fly |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.027
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.026
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.026
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.026
|
Mouse Fly |
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.026
|
|
|
|
regulation of steroid metabolic process
|
GO:0019218 |
39 |
0.026
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.026
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.026
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.026
|
|
|
|
regulation of p38mapk cascade
|
GO:1900744 |
3 |
0.026
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.025
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.025
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.025
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.025
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.025
|
|
|
|
negative regulation of female receptivity
|
GO:0007621 |
2 |
0.025
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.025
|
|
|
|
negative regulation of translational initiation
|
GO:0045947 |
4 |
0.025
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.025
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.025
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.025
|
Mouse |
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.025
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.025
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.025
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
67 |
0.025
|
Mouse |
