Mus musculus

148 known processes

Gnas

GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus

(Aliases: P2,GSP,Oedsml,P1,Oed-Sml,P3,5530400H20Rik,MGC118029,PHP1B,Nesp,PHP1A,Gsa,GPSA,A930027G11Rik,POH,Nespl,Gnasxl,C130027O20Rik,Gnas1)

Gnas biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of insulin receptor signaling pathway GO:0046626 21 0.955
glucose metabolic process GO:0006006 92 0.936
multicellular organism growth GO:0035264 161 0.935
lipid catabolic process GO:0016042 69 0.934
regulation of steroid biosynthetic process GO:0050810 26 0.932
monosaccharide metabolic process GO:0005996 106 0.929
response to alkaloid GO:0043279 34 0.922
Mouse
regulation of glycogen metabolic process GO:0070873 13 0.906
regulation of polysaccharide metabolic process GO:0032881 13 0.902
lipid biosynthetic process GO:0008610 179 0.883
positive regulation of lipid metabolic process GO:0045834 40 0.859
regulation of lipid metabolic process GO:0019216 118 0.843
response to nutrient levels GO:0031667 109 0.843
energy derivation by oxidation of organic compounds GO:0015980 77 0.830
positive regulation of mapk cascade GO:0043410 170 0.815
insulin receptor signaling pathway GO:0008286 49 0.811
energy reserve metabolic process GO:0006112 39 0.786
hexose metabolic process GO:0019318 98 0.784
cellular response to peptide GO:1901653 92 0.782
regulation of carbohydrate metabolic process GO:0006109 75 0.764
regulation of glucan biosynthetic process GO:0010962 7 0.754
regulation of glucose metabolic process GO:0010906 60 0.746
cellular response to external stimulus GO:0071496 88 0.746
generation of precursor metabolites and energy GO:0006091 103 0.741
epithelial tube morphogenesis GO:0060562 303 0.723
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.713
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.706
acylglycerol catabolic process GO:0046464 11 0.695
regulation of blood pressure GO:0008217 93 0.692
positive regulation of steroid biosynthetic process GO:0010893 4 0.692
peptidyl amino acid modification GO:0018193 336 0.685
oxidation reduction process GO:0055114 342 0.673
glycogen metabolic process GO:0005977 32 0.666
cellular lipid metabolic process GO:0044255 323 0.665
triglyceride catabolic process GO:0019433 9 0.664
purine containing compound metabolic process GO:0072521 311 0.663
Human Mouse
regulation of fatty acid metabolic process GO:0019217 28 0.659
regulation of lipid biosynthetic process GO:0046890 54 0.652
cellular phosphate ion homeostasis GO:0030643 2 0.649
anatomical structure homeostasis GO:0060249 145 0.628
positive regulation of lipid biosynthetic process GO:0046889 18 0.626
cellular ion homeostasis GO:0006873 165 0.622
Mouse
polysaccharide biosynthetic process GO:0000271 20 0.597
regulation of camp biosynthetic process GO:0030817 25 0.597
Human Mouse
carbohydrate metabolic process GO:0005975 230 0.594
regulation of cellular amino acid metabolic process GO:0006521 5 0.588
ribonucleoside catabolic process GO:0042454 206 0.588
Human Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.588
mapk cascade GO:0000165 281 0.586
carbohydrate derivative biosynthetic process GO:1901137 183 0.585
Human Mouse
carbohydrate biosynthetic process GO:0016051 74 0.582
cellular carbohydrate metabolic process GO:0044262 119 0.581
autophagic vacuole assembly GO:0000045 13 0.573
cellular response to nutrient levels GO:0031669 64 0.556
glucose import GO:0046323 32 0.551
cellular ketone metabolic process GO:0042180 84 0.551
polysaccharide metabolic process GO:0005976 39 0.551
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.550
Human Mouse
vacuole organization GO:0007033 38 0.540
locomotory behavior GO:0007626 195 0.535
Mouse
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.513
cellular amine metabolic process GO:0044106 44 0.512
response to peptide hormone GO:0043434 127 0.495
nucleotide catabolic process GO:0009166 217 0.494
Human Mouse
second messenger mediated signaling GO:0019932 73 0.488
Human
cellular response to extracellular stimulus GO:0031668 81 0.488
exocrine pancreas development GO:0031017 7 0.486
steroid metabolic process GO:0008202 119 0.472
regulation of carbohydrate biosynthetic process GO:0043255 40 0.464
positive regulation of cellular amine metabolic process GO:0033240 5 0.458
cellular divalent inorganic cation homeostasis GO:0072503 127 0.455
Mouse
circulatory system process GO:0003013 197 0.452
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.443
Human Mouse
circadian rhythm GO:0007623 114 0.440
regulation of blood circulation GO:1903522 93 0.435
Mouse
cellular amino acid metabolic process GO:0006520 103 0.432
carboxylic acid catabolic process GO:0046395 51 0.429
camp biosynthetic process GO:0006171 31 0.422
Human Mouse
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.420
regulation of autophagic vacuole assembly GO:2000785 4 0.415
renin angiotensin regulation of aldosterone production GO:0002018 3 0.406
regulation of peptide transport GO:0090087 91 0.399
positive regulation of glucose metabolic process GO:0010907 21 0.397
macroautophagy GO:0016236 21 0.396
acylglycerol metabolic process GO:0006639 55 0.393
dna metabolic process GO:0006259 303 0.390
activation of janus kinase activity GO:0042976 2 0.390
multicellular organismal homeostasis GO:0048871 164 0.390
connective tissue development GO:0061448 179 0.389
muscle contraction GO:0006936 101 0.386
regulation of steroid metabolic process GO:0019218 39 0.385
regulation of renal output by angiotensin GO:0002019 2 0.379
regulation of generation of precursor metabolites and energy GO:0043467 38 0.375
regulation of nucleotide biosynthetic process GO:0030808 34 0.375
Human Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.368
regulation of circadian sleep wake cycle GO:0042749 3 0.367
positive regulation of cell division GO:0051781 31 0.366
bone mineralization GO:0030282 54 0.365
cellular chemical homeostasis GO:0055082 215 0.359
Mouse
monoamine transport GO:0015844 33 0.357
organic hydroxy compound metabolic process GO:1901615 203 0.356
response to vitamin d GO:0033280 3 0.354
cellular metal ion homeostasis GO:0006875 151 0.352
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.347
Human Mouse
cellular response to insulin stimulus GO:0032869 78 0.347
peptidyl tyrosine modification GO:0018212 145 0.347
glycogen biosynthetic process GO:0005978 14 0.345
triglyceride metabolic process GO:0006641 51 0.344
cellular response to abiotic stimulus GO:0071214 56 0.340
Mouse
organic hydroxy compound transport GO:0015850 93 0.337
regulation of nucleotide metabolic process GO:0006140 169 0.334
Human Mouse
regulation of systemic arterial blood pressure GO:0003073 61 0.330
response to estrogen GO:0043627 24 0.328
intestinal absorption GO:0050892 13 0.324
response to insulin GO:0032868 100 0.323
morphogenesis of a branching structure GO:0001763 203 0.321
Mouse
regulation of cellular catabolic process GO:0031329 242 0.319
Human Mouse
organonitrogen compound catabolic process GO:1901565 264 0.318
Human Mouse
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.316
Human Mouse
positive regulation of fatty acid oxidation GO:0046321 4 0.311
cell division GO:0051301 120 0.311
glucan biosynthetic process GO:0009250 14 0.303
response to extracellular stimulus GO:0009991 127 0.302
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.300
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.299
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.297
Human Mouse
digestion GO:0007586 40 0.296
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.292
fatty acid metabolic process GO:0006631 121 0.289
myotube differentiation GO:0014902 105 0.288
syncytium formation GO:0006949 43 0.282
response to starvation GO:0042594 65 0.282
response to decreased oxygen levels GO:0036293 59 0.280
chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 0.279
negative regulation of protein metabolic process GO:0051248 282 0.274
regulation of hormone levels GO:0010817 211 0.273
nucleotide biosynthetic process GO:0009165 78 0.273
Human Mouse
monocarboxylic acid catabolic process GO:0072329 27 0.272
regulation of smooth muscle contraction GO:0006940 22 0.270
purine nucleoside metabolic process GO:0042278 241 0.269
Human Mouse
regulation of anatomical structure size GO:0090066 178 0.268
developmental maturation GO:0021700 193 0.267
Mouse
regulation of steroid hormone biosynthetic process GO:0090030 4 0.264
positive regulation of camp metabolic process GO:0030816 19 0.262
Human Mouse
positive regulation of hormone metabolic process GO:0032352 3 0.261
rhythmic process GO:0048511 174 0.261
amide transport GO:0042886 138 0.259
response to organonitrogen compound GO:0010243 246 0.258
Mouse
amine metabolic process GO:0009308 45 0.256
glycerolipid metabolic process GO:0046486 122 0.256
cyclic nucleotide mediated signaling GO:0019935 18 0.256
Human
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 13 0.255
hormone secretion GO:0046879 128 0.253
regulation of glutamine family amino acid metabolic process GO:0000820 1 0.252
heart contraction GO:0060047 93 0.251
Mouse
regulation of gluconeogenesis GO:0006111 30 0.248
small gtpase mediated signal transduction GO:0007264 97 0.248
Mouse
regulation of nitrogen cycle metabolic process GO:1903314 1 0.248
cellular response to starvation GO:0009267 57 0.245
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.244
nucleoside metabolic process GO:0009116 246 0.244
Human Mouse
purine nucleotide metabolic process GO:0006163 302 0.244
Human Mouse
intracellular receptor signaling pathway GO:0030522 74 0.243
blood vessel remodeling GO:0001974 33 0.240
positive regulation of kinase activity GO:0033674 155 0.239
male germ line stem cell asymmetric division GO:0048133 2 0.236
calcium ion homeostasis GO:0055074 127 0.236
Mouse
response to growth factor GO:0070848 198 0.235
cellular glucan metabolic process GO:0006073 32 0.235
positive regulation of glycogen metabolic process GO:0070875 8 0.233
syncytium formation by plasma membrane fusion GO:0000768 42 0.232
cation homeostasis GO:0055080 212 0.231
Mouse
regulation of hydrolase activity GO:0051336 246 0.230
Human
regulation of reactive oxygen species metabolic process GO:2000377 40 0.230
muscle adaptation GO:0043500 39 0.230
negative regulation of lipid metabolic process GO:0045833 30 0.230
positive regulation of carbohydrate metabolic process GO:0045913 30 0.229
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.228
Mouse
negative regulation of feeding behavior GO:2000252 1 0.228
tissue homeostasis GO:0001894 115 0.225
negative regulation of phosphate metabolic process GO:0045936 184 0.225
regulation of ion transport GO:0043269 215 0.225
sulfur compound biosynthetic process GO:0044272 37 0.221
proteoglycan biosynthetic process GO:0030166 20 0.221
regulation of purine nucleotide metabolic process GO:1900542 169 0.219
Human Mouse
organic cyclic compound catabolic process GO:1901361 295 0.217
Human Mouse
positive regulation of blood circulation GO:1903524 22 0.216
ribonucleotide catabolic process GO:0009261 208 0.216
Human Mouse
aminoglycan biosynthetic process GO:0006023 15 0.215
biomineral tissue development GO:0031214 64 0.214
cellular response to peptide hormone stimulus GO:0071375 92 0.214
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.212
regulation of secretion GO:0051046 274 0.212
response to ph GO:0009268 14 0.209
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.208
Human
nuclear transport GO:0051169 139 0.208
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.207
regulation of androgen receptor signaling pathway GO:0060765 3 0.207
regulation of apoptotic signaling pathway GO:2001233 197 0.207
organic hydroxy compound biosynthetic process GO:1901617 77 0.206
regulation of nuclear division GO:0051783 56 0.205
regulation of triglyceride metabolic process GO:0090207 17 0.203
negative regulation of blood pressure GO:0045776 22 0.201
peptidyl tyrosine phosphorylation GO:0018108 143 0.200
ribonucleoside metabolic process GO:0009119 245 0.198
Human Mouse
heterocycle catabolic process GO:0046700 280 0.197
Human Mouse
positive regulation of camp biosynthetic process GO:0030819 19 0.195
Human Mouse
organelle fission GO:0048285 170 0.195
metal ion homeostasis GO:0055065 189 0.193
Mouse
positive regulation of gtp catabolic process GO:0033126 85 0.193
Human
autophagy GO:0006914 45 0.191
protein localization to nucleus GO:0034504 121 0.191
positive regulation of hormone biosynthetic process GO:0046886 1 0.190
erk1 and erk2 cascade GO:0070371 77 0.190
intestinal cholesterol absorption GO:0030299 5 0.188
calcium ion transport into cytosol GO:0060402 48 0.186
maintenance of location GO:0051235 89 0.186
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.186
Human Mouse
lateral line system development GO:0048925 1 0.185
regulation of vacuole organization GO:0044088 4 0.185
response to ammonium ion GO:0060359 21 0.185
regulation of purine nucleotide catabolic process GO:0033121 122 0.185
Human
cellular response to growth factor stimulus GO:0071363 197 0.182
regulation of protein localization GO:0032880 231 0.180
response to organic cyclic compound GO:0014070 198 0.180
Mouse
insulin like growth factor receptor signaling pathway GO:0048009 21 0.178
neutral lipid catabolic process GO:0046461 11 0.178
regulation of glycogen biosynthetic process GO:0005979 7 0.176
cellular response to hormone stimulus GO:0032870 150 0.173
release of cytochrome c from mitochondria GO:0001836 23 0.173
purine nucleotide catabolic process GO:0006195 211 0.171
Human Mouse
nucleotide metabolic process GO:0009117 332 0.171
Human Mouse
cytosolic calcium ion homeostasis GO:0051480 70 0.167
Mouse
sterol metabolic process GO:0016125 58 0.167
negative regulation of phosphorus metabolic process GO:0010563 184 0.166
negative regulation of phosphorylation GO:0042326 166 0.165
calcium ion transport GO:0006816 159 0.165
ribonucleotide biosynthetic process GO:0009260 59 0.164
Human Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.164
Human Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.163
Human Mouse
smooth muscle contraction GO:0006939 44 0.161
positive regulation of protein phosphorylation GO:0001934 242 0.159
regulation of mapk cascade GO:0043408 248 0.159
regulation of cell division GO:0051302 76 0.158
germ line stem cell division GO:0042078 2 0.157
ribonucleoside triphosphate metabolic process GO:0009199 220 0.157
Human Mouse
positive regulation of transferase activity GO:0051347 167 0.157
neuropeptide signaling pathway GO:0007218 19 0.157
feeding behavior GO:0007631 62 0.156
Fly
regulation of the force of heart contraction GO:0002026 17 0.156
prostate gland development GO:0030850 48 0.156
muscle system process GO:0003012 141 0.155
positive regulation of triglyceride catabolic process GO:0010898 3 0.154
cellular response to organonitrogen compound GO:0071417 145 0.154
cellular calcium ion homeostasis GO:0006874 119 0.154
Mouse
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.153
Human Mouse
regulation of heart contraction GO:0008016 77 0.153
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.153
Human Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.153
regulation of adrenergic receptor signaling pathway GO:0071877 4 0.152
reactive nitrogen species metabolic process GO:2001057 0 0.150
aminoglycan metabolic process GO:0006022 34 0.150
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.149
Human Mouse
regulation of cellular response to stress GO:0080135 159 0.149
cyclic purine nucleotide metabolic process GO:0052652 43 0.148
Human Mouse
phospholipid metabolic process GO:0006644 87 0.148
blood circulation GO:0008015 195 0.148
Mouse
response to cocaine GO:0042220 14 0.147
negative regulation of intracellular signal transduction GO:1902532 167 0.144
Worm
positive regulation of cellular carbohydrate metabolic process GO:0010676 29 0.141
regulation of feeding behavior GO:0060259 3 0.140
Fly
ras protein signal transduction GO:0007265 77 0.138
Mouse
positive regulation of nucleotide metabolic process GO:0045981 114 0.138
Human Mouse
negative regulation of systemic arterial blood pressure GO:0003085 15 0.137
long term synaptic potentiation GO:0060291 25 0.137
positive regulation of steroid metabolic process GO:0045940 5 0.136
camp metabolic process GO:0046058 40 0.136
Human Mouse
negative regulation of transferase activity GO:0051348 85 0.136
gland development GO:0048732 330 0.135
asymmetric stem cell division GO:0098722 3 0.134
cyclic nucleotide biosynthetic process GO:0009190 44 0.133
Human Mouse
inorganic anion transport GO:0015698 43 0.133
g protein coupled receptor signaling pathway involved in heart process GO:0086103 4 0.133
positive regulation of glycolytic process GO:0045821 4 0.132
heart process GO:0003015 94 0.131
Mouse
serotonin transport GO:0006837 11 0.131
ribonucleoside triphosphate catabolic process GO:0009203 199 0.130
Human Mouse
reactive oxygen species metabolic process GO:0072593 84 0.129
regulation of cellular response to insulin stimulus GO:1900076 30 0.129
nucleoside phosphate biosynthetic process GO:1901293 79 0.128
Human Mouse
glucan metabolic process GO:0044042 32 0.128
positive regulation of lipid catabolic process GO:0050996 6 0.126
regulation of vitamin d biosynthetic process GO:0060556 1 0.125
regulation of transferase activity GO:0051338 263 0.125
cellular polysaccharide metabolic process GO:0044264 38 0.123
regulation of blood coagulation GO:0030193 28 0.123
ribonucleotide metabolic process GO:0009259 291 0.123
Human Mouse
protein kinase b signaling GO:0043491 74 0.122
regulation of kinase activity GO:0043549 249 0.122
positive regulation of organelle organization GO:0010638 128 0.122
negative regulation of apoptotic signaling pathway GO:2001234 104 0.121
regulation of organelle organization GO:0033043 289 0.121
regulation of muscle system process GO:0090257 80 0.121
divalent inorganic cation homeostasis GO:0072507 138 0.119
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.119
Human Mouse
skeletal muscle fiber development GO:0048741 58 0.119
negative regulation of release of cytochrome c from mitochondria GO:0090201 6 0.118
apoptotic mitochondrial changes GO:0008637 48 0.118
tissue remodeling GO:0048771 102 0.117
positive regulation of cell cycle GO:0045787 92 0.117
regulation of the force of heart contraction by chemical signal GO:0003057 5 0.117
regulation of phosphate transport GO:0010966 1 0.116
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.115
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.115
steroid biosynthetic process GO:0006694 47 0.114
regulation of erk1 and erk2 cascade GO:0070372 71 0.114
cellular lipid catabolic process GO:0044242 52 0.114
response to peptide GO:1901652 136 0.113
positive regulation of protein modification process GO:0031401 299 0.113
regulation of fatty acid oxidation GO:0046320 10 0.113
monosaccharide transport GO:0015749 58 0.111
organ growth GO:0035265 117 0.111
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.109
nuclear division GO:0000280 158 0.108
regulation of lipid catabolic process GO:0050994 15 0.108
carbohydrate homeostasis GO:0033500 128 0.108
multicellular organismal response to stress GO:0033555 62 0.108
germline stem cell asymmetric division GO:0098728 2 0.106
axonogenesis GO:0007409 274 0.105
negative regulation of mapk cascade GO:0043409 65 0.105
lipid transport GO:0006869 98 0.104
glutamine family amino acid metabolic process GO:0009064 15 0.104
regulation of lipid storage GO:0010883 20 0.103
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.103
reactive oxygen species biosynthetic process GO:1903409 8 0.103
purine ribonucleoside metabolic process GO:0046128 241 0.102
Human Mouse
respiratory tube development GO:0030323 167 0.102
purine nucleoside triphosphate catabolic process GO:0009146 203 0.102
Human Mouse
negative regulation of mitochondrion organization GO:0010823 9 0.101
cholesterol esterification GO:0034435 3 0.100
covalent chromatin modification GO:0016569 163 0.100
cell maturation GO:0048469 127 0.100
Mouse
aromatic compound catabolic process GO:0019439 286 0.099
Human Mouse
neuronal action potential GO:0019228 54 0.099
hexose biosynthetic process GO:0019319 39 0.098
ribose phosphate metabolic process GO:0019693 291 0.098
Human Mouse
ameboidal type cell migration GO:0001667 128 0.098
Mouse
response to oxygen levels GO:0070482 62 0.098
nucleoside phosphate catabolic process GO:1901292 222 0.097
Human Mouse
brown fat cell differentiation GO:0050873 36 0.097
ammonia assimilation cycle GO:0019676 2 0.097
fatty acid catabolic process GO:0009062 25 0.096
regulation of polysaccharide biosynthetic process GO:0032885 7 0.096
purine ribonucleotide catabolic process GO:0009154 208 0.096
Human Mouse
chromatin modification GO:0016568 187 0.095
muscle cell differentiation GO:0042692 261 0.095
prostate gland stromal morphogenesis GO:0060741 2 0.095
positive regulation of nervous system development GO:0051962 221 0.094
rho protein signal transduction GO:0007266 32 0.093
Mouse
regulation of homeostatic process GO:0032844 182 0.093
negative regulation of muscle contraction GO:0045932 12 0.093
regulation of map kinase activity GO:0043405 120 0.093
glycosyl compound metabolic process GO:1901657 246 0.093
Human Mouse
regulation of response to food GO:0032095 10 0.093
regulation of serotonin uptake GO:0051611 2 0.092
single organism nuclear import GO:1902593 95 0.092
regulation of tube size GO:0035150 57 0.091
negative regulation of cellular protein metabolic process GO:0032269 247 0.089
response to estradiol GO:0032355 12 0.088
synaptic transmission GO:0007268 329 0.088
Fly
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1902238 1 0.088
mammary gland duct morphogenesis GO:0060603 38 0.087
regulation of peptide secretion GO:0002791 77 0.087
gluconeogenesis GO:0006094 39 0.087
nucleoside triphosphate metabolic process GO:0009141 230 0.086
Human Mouse
lactation GO:0007595 25 0.086
regulation of proteolysis GO:0030162 164 0.085
Mouse
negative regulation of smooth muscle cell apoptotic process GO:0034392 1 0.085
regulation of nucleoside metabolic process GO:0009118 130 0.085
Human
vasodilation GO:0042311 28 0.085
response to corticosterone GO:0051412 1 0.085
positive regulation of triglyceride metabolic process GO:0090208 9 0.084
regulation of cell cycle process GO:0010564 160 0.084
glutamate metabolic process GO:0006536 9 0.083
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.083
striated muscle contraction GO:0006941 45 0.083
regulation of ossification GO:0030278 112 0.083
glycerolipid catabolic process GO:0046503 16 0.083
heart morphogenesis GO:0003007 178 0.083
positive regulation of nucleoside metabolic process GO:0045979 91 0.082
Human
prostate glandular acinus development GO:0060525 12 0.082
negative regulation of carbohydrate metabolic process GO:0045912 19 0.082
response to lipopolysaccharide GO:0032496 128 0.081
cgmp metabolic process GO:0046068 20 0.081
protein localization to organelle GO:0033365 185 0.081
insulin receptor signaling pathway via phosphatidylinositol 3 kinase GO:0038028 3 0.081
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.080
negative regulation of circadian rhythm GO:0042754 8 0.080
small molecule biosynthetic process GO:0044283 132 0.079
lung vasculature development GO:0060426 7 0.079
nuclear import GO:0051170 95 0.079
small molecule catabolic process GO:0044282 71 0.079
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1990127 1 0.078
carboxylic acid biosynthetic process GO:0046394 86 0.078
positive regulation of leukocyte proliferation GO:0070665 73 0.078
mitotic nuclear division GO:0007067 48 0.078
neutral lipid metabolic process GO:0006638 57 0.078
regulation of phospholipid biosynthetic process GO:0071071 3 0.078
circadian sleep wake cycle GO:0042745 5 0.077
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.077
apoptotic signaling pathway GO:0097190 306 0.076
drug catabolic process GO:0042737 2 0.076
regulation of corticosterone secretion GO:2000852 2 0.076
monocarboxylic acid metabolic process GO:0032787 191 0.076
angiogenesis GO:0001525 201 0.076
Mouse
anion transport GO:0006820 177 0.074
regulation of blood vessel size GO:0050880 56 0.074
organonitrogen compound biosynthetic process GO:1901566 192 0.074
Human Mouse
urogenital system development GO:0001655 261 0.073
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.073
organic anion transport GO:0015711 137 0.073
glycosaminoglycan biosynthetic process GO:0006024 15 0.072
corticosterone secretion GO:0035934 3 0.072
cellular polysaccharide biosynthetic process GO:0033692 19 0.072
cyclic nucleotide metabolic process GO:0009187 59 0.072
Human Mouse
phosphate ion transport GO:0006817 3 0.071
negative regulation of neurotransmitter transport GO:0051589 7 0.071
proteoglycan metabolic process GO:0006029 38 0.070
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.070
stress activated protein kinase signaling cascade GO:0031098 81 0.070
gliogenesis GO:0042063 141 0.070
response to bile acid GO:1903412 1 0.069
hormone biosynthetic process GO:0042446 16 0.069
adult locomotory behavior GO:0008344 91 0.069
organelle assembly GO:0070925 177 0.068
regulation of response to reactive oxygen species GO:1901031 9 0.068
regulation of lipid kinase activity GO:0043550 14 0.068
pyruvate metabolic process GO:0006090 28 0.068
regulation of cell migration GO:0030334 219 0.068
Mouse
intrinsic apoptotic signaling pathway in response to osmotic stress GO:0008627 2 0.068
purine nucleoside catabolic process GO:0006152 205 0.068
Human Mouse
acid secretion GO:0046717 33 0.067
positive regulation of vasoconstriction GO:0045907 4 0.067
glycerolipid biosynthetic process GO:0045017 50 0.067
lipid storage GO:0019915 36 0.067
nucleoside catabolic process GO:0009164 206 0.066
Human Mouse
regulation of camp metabolic process GO:0030814 30 0.066
Human Mouse
positive regulation of protein kinase activity GO:0045860 144 0.066
wound healing GO:0042060 157 0.066
Human Mouse
organic acid catabolic process GO:0016054 51 0.066
purine ribonucleotide biosynthetic process GO:0009152 59 0.065
Human Mouse
regulation of release of cytochrome c from mitochondria GO:0090199 11 0.065
positive regulation of activated t cell proliferation GO:0042104 8 0.065
inositol lipid mediated signaling GO:0048017 41 0.065
positive regulation of adrenergic receptor signaling pathway GO:0071879 3 0.065
ribose phosphate biosynthetic process GO:0046390 59 0.065
Human Mouse
regulation of cholesterol esterification GO:0010872 2 0.065
regulation of cell size GO:0008361 72 0.065
regulation of bone mineralization GO:0030500 31 0.065
myotube cell development GO:0014904 60 0.064
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.064
regulation of mitochondrion organization GO:0010821 27 0.064
pancreas development GO:0031016 57 0.064
regulation of protein transport GO:0051223 163 0.064
chromatin organization GO:0006325 206 0.064
cerebellar granule cell precursor proliferation GO:0021930 10 0.063
lipid localization GO:0010876 126 0.063
regulation of protein binding GO:0043393 60 0.063
digestive system development GO:0055123 200 0.063
purine nucleoside triphosphate metabolic process GO:0009144 226 0.063
Human Mouse
dna dealkylation GO:0035510 11 0.063
regulation of cellular component biogenesis GO:0044087 181 0.062
regulation of ras protein signal transduction GO:0046578 114 0.062
Human
regulation of receptor activity GO:0010469 41 0.062
t cell proliferation GO:0042098 120 0.061
muscle fiber development GO:0048747 76 0.061
stress activated mapk cascade GO:0051403 80 0.061

Gnas disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.476
Human
bone remodeling disease DOID:0080005 0 0.152
bone disease DOID:0080001 0 0.152
disease of anatomical entity DOID:7 0 0.152
musculoskeletal system disease DOID:17 0 0.152
connective tissue disease DOID:65 0 0.152
nervous system disease DOID:863 0 0.076
central nervous system disease DOID:331 0 0.076
diabetes mellitus DOID:9351 0 0.072
type 2 diabetes mellitus DOID:9352 0 0.072
carbohydrate metabolism disease DOID:0050013 0 0.072
glucose metabolism disease DOID:4194 0 0.072
acquired metabolic disease DOID:0060158 0 0.072
hypertension DOID:10763 0 0.067
artery disease DOID:0050828 0 0.067
vascular disease DOID:178 0 0.067
essential hypertension DOID:10825 0 0.067
cardiovascular system disease DOID:1287 0 0.067