Mus musculus

67 known processes

Gnat2

guanine nucleotide binding protein, alpha transducing 2

(Aliases: Gnat-2,Gt-2,Tcalpha,AW490837)

Gnat2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gland development GO:0048732 330 0.189
rhodopsin mediated signaling pathway GO:0016056 4 0.186
phototransduction GO:0007602 17 0.176
metal ion homeostasis GO:0055065 189 0.123
Mouse
regulation of hormone levels GO:0010817 211 0.106
organonitrogen compound biosynthetic process GO:1901566 192 0.103
Mouse
dna metabolic process GO:0006259 303 0.103
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.096
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.095
Mouse Fly
retinal cone cell development GO:0046549 8 0.086
cation homeostasis GO:0055080 212 0.084
Mouse
response to radiation GO:0009314 165 0.084
sensory perception GO:0007600 245 0.081
spermatogenesis GO:0007283 284 0.076
multicellular organism growth GO:0035264 161 0.061
Mouse
macromolecule methylation GO:0043414 120 0.061
Mouse
nucleotide metabolic process GO:0009117 332 0.059
Mouse
positive regulation of glial cell proliferation GO:0060252 4 0.057
organic hydroxy compound metabolic process GO:1901615 203 0.055
anatomical structure homeostasis GO:0060249 145 0.051
Mouse
response to light stimulus GO:0009416 135 0.051
purine nucleotide metabolic process GO:0006163 302 0.051
Mouse
l amino acid transport GO:0015807 32 0.050
detection of stimulus GO:0051606 84 0.049
spermatid differentiation GO:0048515 115 0.048
spermatid development GO:0007286 108 0.048
cellular amine metabolic process GO:0044106 44 0.047
phenol containing compound biosynthetic process GO:0046189 21 0.045
multicellular organismal homeostasis GO:0048871 164 0.045
Mouse
amine metabolic process GO:0009308 45 0.045
positive regulation of cell death GO:0010942 224 0.043
positive regulation of apoptotic process GO:0043065 217 0.042
protein maturation GO:0051604 176 0.042
phototransduction visible light GO:0007603 6 0.041
cellular amino acid metabolic process GO:0006520 103 0.041
intracellular protein transport GO:0006886 204 0.041
cellular homeostasis GO:0019725 240 0.041
Mouse
purine containing compound metabolic process GO:0072521 311 0.039
Mouse
sensory organ morphogenesis GO:0090596 242 0.039
cellular ketone metabolic process GO:0042180 84 0.037
retina morphogenesis in camera type eye GO:0060042 45 0.037
response to organonitrogen compound GO:0010243 246 0.037
Mouse
response to inorganic substance GO:0010035 96 0.036
response to organic cyclic compound GO:0014070 198 0.036
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.036
peptide secretion GO:0002790 114 0.036
regulation of cell migration GO:0030334 219 0.036
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.035
Mouse
cell type specific apoptotic process GO:0097285 268 0.035
forebrain development GO:0030900 302 0.035
Mouse
organelle localization GO:0051640 179 0.035
Worm Fly
l alpha amino acid transmembrane transport GO:1902475 23 0.035
regulation of cellular amino acid metabolic process GO:0006521 5 0.034
eye photoreceptor cell differentiation GO:0001754 41 0.034
macromolecule catabolic process GO:0009057 281 0.034
Mouse
ossification GO:0001503 216 0.034
Mouse
oxidation reduction process GO:0055114 342 0.033
Mouse
cellular ion homeostasis GO:0006873 165 0.033
Mouse
protein processing GO:0016485 163 0.033
innate immune response GO:0045087 157 0.032
organic cyclic compound catabolic process GO:1901361 295 0.032
Mouse
male gamete generation GO:0048232 285 0.032
detection of light stimulus GO:0009583 25 0.032
regulation of protein localization GO:0032880 231 0.031
Fly
detection of abiotic stimulus GO:0009582 60 0.031
ion transmembrane transport GO:0034220 361 0.031
retina development in camera type eye GO:0060041 119 0.031
circulatory system process GO:0003013 197 0.030
Mouse
apoptotic signaling pathway GO:0097190 306 0.030
cellular response to abiotic stimulus GO:0071214 56 0.030
Mouse
camera type eye development GO:0043010 266 0.030
phenol containing compound metabolic process GO:0018958 60 0.030
rhythmic process GO:0048511 174 0.030
divalent inorganic cation homeostasis GO:0072507 138 0.029
Mouse
positive regulation of programmed cell death GO:0043068 218 0.029
alpha amino acid metabolic process GO:1901605 59 0.029
eye photoreceptor cell development GO:0042462 31 0.029
cellular chemical homeostasis GO:0055082 215 0.029
Mouse
photoreceptor cell development GO:0042461 40 0.029
dna modification GO:0006304 50 0.028
Mouse
protein catabolic process GO:0030163 221 0.028
Mouse
purine nucleotide biosynthetic process GO:0006164 65 0.028
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.028
Mouse
response to metal ion GO:0010038 47 0.028
response to oxygen levels GO:0070482 62 0.028
respiratory system development GO:0060541 190 0.028
cellular response to light stimulus GO:0071482 19 0.028
energy derivation by oxidation of organic compounds GO:0015980 77 0.028
Mouse
positive regulation of nervous system development GO:0051962 221 0.027
reactive oxygen species metabolic process GO:0072593 84 0.027
detection of external stimulus GO:0009581 61 0.027
cation transport GO:0006812 399 0.027
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.026
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
cellular response to cytokine stimulus GO:0071345 189 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.026
Mouse
potassium ion transport GO:0006813 52 0.026
neural precursor cell proliferation GO:0061351 121 0.026
Fly
embryonic skeletal system development GO:0048706 120 0.026
Mouse
endochondral bone morphogenesis GO:0060350 50 0.026
Mouse
sensory perception of chemical stimulus GO:0007606 51 0.026
Mouse
regulation of membrane potential GO:0042391 192 0.025
Mouse Fly
embryonic organ morphogenesis GO:0048562 276 0.025
Mouse
cation transmembrane transport GO:0098655 266 0.025
embryonic limb morphogenesis GO:0030326 126 0.025
Mouse
cellular response to radiation GO:0071478 28 0.025
protein modification by small protein conjugation GO:0032446 187 0.025
nucleoside phosphate biosynthetic process GO:1901293 79 0.024
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
Mouse
organophosphate biosynthetic process GO:0090407 122 0.023
Mouse
modification dependent macromolecule catabolic process GO:0043632 133 0.023
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.023
regulation of neurotransmitter levels GO:0001505 87 0.023
chromatin modification GO:0016568 187 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.023
Mouse
nitrogen compound transport GO:0071705 271 0.023
regulation of synaptic plasticity GO:0048167 87 0.022
regulation of purine nucleotide metabolic process GO:1900542 169 0.022
Mouse
ribose phosphate metabolic process GO:0019693 291 0.022
Mouse
protein targeting GO:0006605 143 0.022
regulation of nucleotide metabolic process GO:0006140 169 0.022
Mouse
respiratory tube development GO:0030323 167 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
c21 steroid hormone biosynthetic process GO:0006700 3 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
ribonucleotide metabolic process GO:0009259 291 0.021
Mouse
central nervous system neuron differentiation GO:0021953 162 0.021
Mouse
peptide hormone secretion GO:0030072 109 0.021
ribonucleotide biosynthetic process GO:0009260 59 0.021
Mouse
progesterone metabolic process GO:0042448 4 0.021
pigmentation GO:0043473 71 0.021
Mouse
pigment biosynthetic process GO:0046148 26 0.021
inflammatory response GO:0006954 244 0.021
negative regulation of immune system process GO:0002683 209 0.021
cytoplasmic transport GO:0016482 234 0.021
multi organism behavior GO:0051705 62 0.021
Mouse
protein ubiquitination GO:0016567 171 0.020
stem cell proliferation GO:0072089 117 0.020
Fly
embryonic appendage morphogenesis GO:0035113 126 0.020
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.020
Mouse
purine containing compound biosynthetic process GO:0072522 70 0.020
Mouse
mitochondrion distribution GO:0048311 4 0.020
glycosyl compound metabolic process GO:1901657 246 0.020
Mouse
neurotransmitter transport GO:0006836 76 0.020
positive regulation of secretion GO:0051047 130 0.020
protein localization to organelle GO:0033365 185 0.020
nucleoside metabolic process GO:0009116 246 0.019
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.019
positive regulation of protein modification process GO:0031401 299 0.019
replacement ossification GO:0036075 26 0.019
Mouse
defense response to virus GO:0051607 68 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
developmental pigmentation GO:0048066 40 0.018
Mouse
leukocyte differentiation GO:0002521 342 0.018
Mouse
digestive system development GO:0055123 200 0.018
regulation of defense response GO:0031347 233 0.018
circadian regulation of gene expression GO:0032922 48 0.018
lung development GO:0030324 164 0.018
immune effector process GO:0002252 321 0.018
response to hypoxia GO:0001666 58 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
heterocycle catabolic process GO:0046700 280 0.017
Mouse
methylation GO:0032259 134 0.017
Mouse
purine nucleoside monophosphate metabolic process GO:0009126 81 0.017
photoreceptor cell differentiation GO:0046530 52 0.017
cellular amide metabolic process GO:0043603 58 0.017
aldosterone metabolic process GO:0032341 2 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
ear morphogenesis GO:0042471 118 0.017
regulation of ion transport GO:0043269 215 0.017
synaptic transmission GO:0007268 329 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
cellular response to gonadotropin stimulus GO:0071371 4 0.017
detection of visible light GO:0009584 14 0.017
alcohol metabolic process GO:0006066 116 0.017
visual perception GO:0007601 52 0.017
nucleoside monophosphate metabolic process GO:0009123 85 0.017
germ cell development GO:0007281 185 0.017
fat soluble vitamin biosynthetic process GO:0042362 4 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.016
ribonucleoside monophosphate metabolic process GO:0009161 80 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.016
mitochondrion organization GO:0007005 134 0.016
cytokine production GO:0001816 319 0.016
cytokine mediated signaling pathway GO:0019221 115 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
Mouse
mitotic cell cycle process GO:1903047 159 0.016
Worm
positive regulation of transferase activity GO:0051347 167 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
neuroblast differentiation GO:0014016 2 0.016
tendon cell differentiation GO:0035990 4 0.016
regulation of cell motility GO:2000145 236 0.016
Mouse
dna alkylation GO:0006305 43 0.016
Mouse
hormone metabolic process GO:0042445 86 0.016
sensory perception of umami taste GO:0050917 4 0.016
Mouse
sterol transport GO:0015918 38 0.016
intestinal epithelial structure maintenance GO:0060729 4 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
extracellular matrix organization GO:0030198 147 0.015
nucleotide biosynthetic process GO:0009165 78 0.015
Mouse
engulfment of apoptotic cell GO:0043652 3 0.015
embryonic skeletal system morphogenesis GO:0048704 91 0.015
Mouse
regulation of peptide transport GO:0090087 91 0.015
nuclear transport GO:0051169 139 0.015
neuroblast proliferation GO:0007405 49 0.015
Fly
neural retina development GO:0003407 41 0.015
regulation of myeloid leukocyte differentiation GO:0002761 58 0.015
Mouse
regulation of body fluid levels GO:0050878 162 0.015
Mouse
negative regulation of cholesterol transport GO:0032375 4 0.015
aromatic compound catabolic process GO:0019439 286 0.015
Mouse
cellular response to inorganic substance GO:0071241 37 0.015
nucleobase containing small molecule metabolic process GO:0055086 352 0.015
Mouse
negative regulation of cell proliferation GO:0008285 296 0.015
cyclic nucleotide metabolic process GO:0009187 59 0.015
Mouse
skeletal muscle organ development GO:0060538 163 0.015
positive regulation of proteolysis GO:0045862 85 0.015
dopamine metabolic process GO:0042417 23 0.015
cellular alcohol biosynthetic process GO:0044108 3 0.015
cellular response to organonitrogen compound GO:0071417 145 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
regulation of circadian rhythm GO:0042752 58 0.014
negative regulation of protein transport GO:0051224 46 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
amide transport GO:0042886 138 0.014
connective tissue development GO:0061448 179 0.014
Mouse
fat soluble vitamin catabolic process GO:0042363 1 0.014
b cell activation GO:0042113 161 0.014
tyrosine metabolic process GO:0006570 4 0.014
fat cell differentiation GO:0045444 160 0.014
circadian rhythm GO:0007623 114 0.014
sympathetic nervous system development GO:0048485 22 0.014
cellular calcium ion homeostasis GO:0006874 119 0.014
Mouse
cellular alcohol metabolic process GO:0044107 3 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
cellular protein catabolic process GO:0044257 155 0.014
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
cell substrate adhesion GO:0031589 130 0.013
mineralocorticoid biosynthetic process GO:0006705 1 0.013
response to acid chemical GO:0001101 111 0.013
limb morphogenesis GO:0035108 149 0.013
Mouse
cellular lipid metabolic process GO:0044255 323 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.013
extracellular structure organization GO:0043062 148 0.013
regulation of cellular ketone metabolic process GO:0010565 66 0.013
tissue homeostasis GO:0001894 115 0.013
Mouse
atp metabolic process GO:0046034 75 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
Mouse
amino acid transmembrane transport GO:0003333 37 0.013
inner ear morphogenesis GO:0042472 101 0.013
regulation of t cell activation GO:0050863 170 0.013
sequestering of calcium ion GO:0051208 18 0.013
purine ribonucleotide biosynthetic process GO:0009152 59 0.013
Mouse
cartilage development GO:0051216 140 0.013
Mouse
positive regulation of secretion by cell GO:1903532 114 0.013
ribonucleoside monophosphate catabolic process GO:0009158 57 0.013
regulation of hydrolase activity GO:0051336 246 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
Mouse
multicellular organismal signaling GO:0035637 91 0.013
Fly
atp catabolic process GO:0006200 55 0.013
regulation of protein transport GO:0051223 163 0.013
respiratory system process GO:0003016 25 0.012
sperm motility GO:0030317 47 0.012
regulation of microvillus assembly GO:0032534 3 0.012
schwann cell proliferation GO:0014010 2 0.012
regulation of inflammatory response GO:0050727 147 0.012
organelle assembly GO:0070925 177 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
Mouse
erythrocyte differentiation GO:0030218 88 0.012
covalent chromatin modification GO:0016569 163 0.012
regulation of defense response to bacterium GO:1900424 3 0.012
retina homeostasis GO:0001895 23 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
Mouse
activation of immune response GO:0002253 138 0.012
response to lipopolysaccharide GO:0032496 128 0.012
regulation of neural retina development GO:0061074 3 0.012
regulation of protein catabolic process GO:0042176 108 0.012
Mouse
potassium ion homeostasis GO:0055075 4 0.012
response to calcium ion GO:0051592 20 0.012
dephosphorylation GO:0016311 129 0.012
regulation of osteoblast differentiation GO:0045667 67 0.012
Mouse
multi multicellular organism process GO:0044706 109 0.012
Mouse
epithelial tube morphogenesis GO:0060562 303 0.012
Mouse
regulation of neural precursor cell proliferation GO:2000177 70 0.012
divalent inorganic cation transport GO:0072511 178 0.012
neuron death GO:0070997 154 0.012
organic acid biosynthetic process GO:0016053 86 0.012
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.012
regulation of proteolysis GO:0030162 164 0.012
Mouse
response to endoplasmic reticulum stress GO:0034976 53 0.012
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
Mouse
cellular response to organic cyclic compound GO:0071407 87 0.012
regulation of metal ion transport GO:0010959 106 0.012
positive regulation of peptide hormone secretion GO:0090277 31 0.011
nucleoside catabolic process GO:0009164 206 0.011
Mouse
cyclic purine nucleotide metabolic process GO:0052652 43 0.011
Mouse
lipid biosynthetic process GO:0008610 179 0.011
regulation of anatomical structure size GO:0090066 178 0.011
cell division GO:0051301 120 0.011
Fly
establishment of glial blood brain barrier GO:0060857 2 0.011
Fly
response to peptide hormone GO:0043434 127 0.011
cellularization GO:0007349 1 0.011
phospholipid metabolic process GO:0006644 87 0.011
skin development GO:0043588 220 0.011
Mouse
chromatin organization GO:0006325 206 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
Mouse
transmission of nerve impulse GO:0019226 76 0.011
Fly
action potential GO:0001508 78 0.011
Mouse Fly
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.011
epithelial cell proliferation GO:0050673 174 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
Mouse
development of primary female sexual characteristics GO:0046545 73 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
Mouse
er nucleus signaling pathway GO:0006984 27 0.011
binding of sperm to zona pellucida GO:0007339 34 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
divalent metal ion transport GO:0070838 172 0.011
cellular response to topologically incorrect protein GO:0035967 25 0.011
dna repair GO:0006281 107 0.011
stem cell development GO:0048864 219 0.011
transmembrane transport GO:0055085 412 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
acute inflammatory response GO:0002526 41 0.011
cellular response to oxidative stress GO:0034599 76 0.011
cell cell recognition GO:0009988 44 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
Mouse
regulation of multi organism process GO:0043900 111 0.011
auditory receptor cell fate specification GO:0042667 1 0.011
negative regulation of cell motility GO:2000146 61 0.011
regulation of peptidase activity GO:0052547 96 0.011
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
hemostasis GO:0007599 78 0.011
Mouse
leukocyte mediated immunity GO:0002443 174 0.011
gonad development GO:0008406 141 0.011
camera type eye photoreceptor cell differentiation GO:0060219 15 0.011
cellular potassium ion transport GO:0071804 43 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
defense response to gram positive bacterium GO:0050830 50 0.010
activation of cysteine type endopeptidase activity GO:0097202 27 0.010
negative regulation of molecular function GO:0044092 258 0.010
development of primary sexual characteristics GO:0045137 143 0.010
regulation of secretion GO:0051046 274 0.010
inorganic cation transmembrane transport GO:0098662 207 0.010
negative regulation of cholesterol efflux GO:0090370 4 0.010
nucleoside monophosphate catabolic process GO:0009125 59 0.010
cellular response to peptide GO:1901653 92 0.010
negative regulation of synaptic transmission glutamatergic GO:0051967 4 0.010
digestive tract development GO:0048565 190 0.010
organelle fission GO:0048285 170 0.010
lipid localization GO:0010876 126 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
regulation of chromosome organization GO:0033044 83 0.010
adult locomotory behavior GO:0008344 91 0.010
rho protein signal transduction GO:0007266 32 0.010
Mouse
regulation of lymphocyte activation GO:0051249 240 0.010
regulation of chromatin organization GO:1902275 57 0.010
insulin secretion GO:0030073 89 0.010
positive regulation of homeostatic process GO:0032846 64 0.010
regulation of neurotransmitter transport GO:0051588 35 0.010
regulation of complement activation classical pathway GO:0030450 1 0.010
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.010
Mouse
regulation of kinase activity GO:0043549 249 0.010
skeletal system development GO:0001501 356 0.010
Mouse
mitotic cell cycle GO:0000278 195 0.010
Worm

Gnat2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.099
eye and adnexa disease DOID:1492 0 0.099
disease of anatomical entity DOID:7 0 0.099
sensory system disease DOID:0050155 0 0.099
retinal disease DOID:5679 0 0.099
eye disease DOID:5614 0 0.099
retinitis pigmentosa DOID:10584 0 0.058
retinal degeneration DOID:8466 0 0.058
musculoskeletal system disease DOID:17 0 0.026
connective tissue disease DOID:65 0 0.026
hematopoietic system disease DOID:74 0 0.025
immune system disease DOID:2914 0 0.025
bone disease DOID:0080001 0 0.020
disease of cellular proliferation DOID:14566 0 0.016
bone development disease DOID:0080006 0 0.013
cancer DOID:162 0 0.013
organ system cancer DOID:0050686 0 0.012
inherited metabolic disorder DOID:655 0 0.011
disease of metabolism DOID:0014667 0 0.011