|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.366
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.310
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.252
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.246
|
Mouse |
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
57 |
0.240
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.227
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.222
|
Mouse |
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.219
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.209
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.208
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.202
|
Mouse |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.189
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.186
|
Worm Fly |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.175
|
Mouse Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.173
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.169
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.165
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.164
|
Mouse |
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.151
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.151
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.148
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.144
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.142
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.142
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.139
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.137
|
Mouse |
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.132
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.124
|
Fly |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.121
|
Mouse |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.119
|
Mouse |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.114
|
Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.113
|
Mouse |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.111
|
Mouse |
|
|
protein polymerization
|
GO:0051258 |
57 |
0.110
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.109
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.104
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.102
|
Mouse |
|
|
endocytosis
|
GO:0006897 |
168 |
0.101
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.097
|
Mouse |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.097
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.097
|
Mouse |
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.096
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.094
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.094
|
Mouse |
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.093
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.092
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.092
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.090
|
Mouse Fly |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.089
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.087
|
Mouse |
|
|
learning
|
GO:0007612 |
98 |
0.085
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.084
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.084
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.084
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.084
|
Mouse |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.081
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.081
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.080
|
Mouse |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.079
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.079
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.079
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.079
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.078
|
Mouse |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.078
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.077
|
Fly |
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.077
|
Worm Fly |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.076
|
Mouse |
|
|
membrane organization
|
GO:0061024 |
245 |
0.076
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.076
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.075
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.075
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.074
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.074
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.074
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.073
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.073
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.072
|
Mouse |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.072
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.071
|
Mouse |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.071
|
Mouse |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.070
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.070
|
Worm Fly |
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.070
|
Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.069
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.068
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.068
|
Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.067
|
Worm |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.066
|
Mouse |
|
|
cognition
|
GO:0050890 |
149 |
0.066
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.065
|
Mouse |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.065
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.064
|
Fly |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.064
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.064
|
Mouse |
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.063
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.063
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.060
|
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.060
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.060
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.059
|
Mouse |
|
|
protein maturation
|
GO:0051604 |
176 |
0.059
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.059
|
Worm Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.058
|
Mouse |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.058
|
Mouse |
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.058
|
Fly |
|
|
associative learning
|
GO:0008306 |
61 |
0.057
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.055
|
Mouse |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.055
|
Mouse |
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
48 |
0.053
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.053
|
Mouse |
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.052
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.052
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.052
|
Mouse |
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.051
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.051
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.051
|
Mouse |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.050
|
Mouse |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.050
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.049
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.049
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.049
|
Mouse |
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.048
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.048
|
|
|
|
mitochondrion transport along microtubule
|
GO:0047497 |
3 |
0.048
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.047
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.047
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.047
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.047
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.046
|
|
|
|
regulation of clathrin mediated endocytosis
|
GO:2000369 |
4 |
0.046
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.046
|
Mouse |
|
|
protein targeting
|
GO:0006605 |
143 |
0.045
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.045
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.045
|
Mouse |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.044
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.044
|
|
|
|
calcium ion dependent exocytosis
|
GO:0017156 |
35 |
0.044
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
69 |
0.044
|
|
|
|
regulation of ovulation
|
GO:0060278 |
3 |
0.044
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.043
|
Mouse |
|
|
ear development
|
GO:0043583 |
200 |
0.043
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.042
|
Mouse |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.042
|
Mouse |
|
|
vesicle organization
|
GO:0016050 |
60 |
0.042
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.042
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.042
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.041
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.041
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.041
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.041
|
Mouse |
|
|
learning or memory
|
GO:0007611 |
148 |
0.040
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.040
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.040
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.040
|
Mouse |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.040
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.040
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.039
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.039
|
Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.039
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.039
|
Mouse |
|
|
synapse organization
|
GO:0050808 |
125 |
0.039
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.039
|
Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.039
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.039
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.038
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.038
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.038
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.038
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.038
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.038
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.037
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.037
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.037
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.037
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.037
|
Fly |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.037
|
|
|
|
fast calcium ion dependent exocytosis of neurotransmitter
|
GO:0098746 |
1 |
0.037
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.036
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.036
|
Worm Fly |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.036
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.036
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.036
|
Mouse |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.036
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.036
|
Mouse |
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.035
|
Fly |
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.035
|
Fly |
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.035
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.035
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.035
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.035
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.035
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.035
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.035
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.035
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.035
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.034
|
Mouse |
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.034
|
Mouse |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.034
|
|
|
|
positive regulation of necrotic cell death
|
GO:0010940 |
1 |
0.034
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.034
|
Mouse |
|
|
immune effector process
|
GO:0002252 |
321 |
0.033
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.033
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.033
|
Mouse |
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.033
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.033
|
Mouse |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.033
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.033
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.033
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.033
|
Mouse |
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.033
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.032
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.032
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.032
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.032
|
Mouse |
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.032
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.032
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.032
|
|
|
|
maintenance of presynaptic active zone structure
|
GO:0048790 |
1 |
0.032
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.031
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.031
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.031
|
Mouse |
|
|
membrane tubulation
|
GO:0097320 |
4 |
0.031
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.031
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.031
|
Mouse |
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.031
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.031
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.031
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.031
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.031
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.030
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.030
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.030
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.030
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.030
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.030
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.030
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.029
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.029
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.029
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.029
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.029
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.029
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.029
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.029
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.029
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.029
|
Mouse |
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.028
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.028
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.028
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.028
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.028
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.027
|
Mouse |
|
|
response to insulin
|
GO:0032868 |
100 |
0.027
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.027
|
Mouse |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.027
|
Mouse |
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.027
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.027
|
Fly |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.027
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.027
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.027
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.027
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.027
|
Mouse |
|
|
oocyte construction
|
GO:0007308 |
2 |
0.027
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.027
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.027
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.026
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.026
|
|
|
|
vesicle fusion
|
GO:0006906 |
16 |
0.026
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.026
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.026
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.026
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.026
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
26 |
0.026
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.026
|
Mouse |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.026
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
20 |
0.025
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.025
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.025
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.025
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.025
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.024
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.024
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.024
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.024
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.024
|
Mouse |
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.024
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.024
|
|
|
|
positive regulation of vesicle fusion
|
GO:0031340 |
2 |
0.024
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.024
|
Mouse |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.023
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.023
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.023
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.023
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.023
|
Worm |
|
|
protein secretion
|
GO:0009306 |
111 |
0.023
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.023
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.023
|
Mouse |
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.023
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.023
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.023
|
Mouse |
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.023
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.022
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.022
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.022
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.022
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.022
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.022
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.022
|
Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.022
|
|
|
|
adult walking behavior
|
GO:0007628 |
41 |
0.022
|
|
|
|
detection of light stimulus
|
GO:0009583 |
25 |
0.022
|
Mouse |
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.022
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.022
|
|
|
|
lipid modification
|
GO:0030258 |
65 |
0.022
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.022
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.022
|
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.022
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.022
|
Fly |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.021
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.021
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.021
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.021
|
Mouse |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.021
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.021
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.021
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.021
|
|
|
|
regulation of extent of cell growth
|
GO:0061387 |
52 |
0.021
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.021
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.021
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.021
|
|
|
|
establishment of mitochondrion localization
|
GO:0051654 |
4 |
0.021
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.020
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
35 |
0.020
|
Mouse |
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
30 |
0.020
|
|
|
|
microtubule based transport
|
GO:0010970 |
50 |
0.020
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.020
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.020
|
|
|
|
sialylation
|
GO:0097503 |
14 |
0.020
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.020
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.020
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.020
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.020
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.020
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.020
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.020
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.020
|
Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.020
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.020
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.020
|
|
|
|
fasciculation of sensory neuron axon
|
GO:0097155 |
3 |
0.020
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.020
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.019
|
Mouse |
|
|
male gamete generation
|
GO:0048232 |
285 |
0.019
|
|
|
|
dendritic spine development
|
GO:0060996 |
30 |
0.019
|
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
45 |
0.019
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.019
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.019
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.019
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.019
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.019
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.019
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.019
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.019
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.019
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.019
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.019
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.019
|
|
|
|
axon cargo transport
|
GO:0008088 |
33 |
0.018
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.018
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.018
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.018
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.018
|
Fly |
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.018
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.018
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.018
|
|
|
|
organelle transport along microtubule
|
GO:0072384 |
14 |
0.018
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.018
|
Mouse |
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.018
|
|
|
|
negative regulation of ovulation
|
GO:0060280 |
1 |
0.018
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.018
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.018
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.018
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.018
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
45 |
0.018
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.018
|
|
|
|
detection of external stimulus
|
GO:0009581 |
61 |
0.017
|
Mouse |
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.017
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.017
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.017
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.017
|
Mouse |
|
|
rap protein signal transduction
|
GO:0032486 |
3 |
0.017
|
|
|
|
microtubule sliding
|
GO:0051012 |
1 |
0.017
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.017
|
Mouse |
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.017
|
Mouse |
|
|
negative regulation of neuron projection regeneration
|
GO:0070571 |
3 |
0.017
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.017
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.017
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.017
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.017
|
|
|
|
response to iron ion
|
GO:0010039 |
4 |
0.017
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
41 |
0.017
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.017
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.017
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.017
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.017
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.017
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.017
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.017
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.016
|
|
|
|
positive regulation of protein export from nucleus
|
GO:0046827 |
4 |
0.016
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.016
|
|
|
|
sensory perception of light stimulus
|
GO:0050953 |
54 |
0.016
|
Mouse |
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.016
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.016
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.016
|
|
|
|
nerve development
|
GO:0021675 |
67 |
0.016
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.016
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.016
|
Mouse Fly |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.016
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.016
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.016
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
85 |
0.016
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.016
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.015
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.015
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.015
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.015
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.015
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.015
|
Mouse |
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.015
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.015
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
26 |
0.015
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.015
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.015
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.015
|
Mouse |
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
26 |
0.015
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.015
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.015
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.015
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.015
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.015
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.015
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.015
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.015
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.014
|
Mouse |
|
|
regulation of long term neuronal synaptic plasticity
|
GO:0048169 |
19 |
0.014
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.014
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.014
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.014
|
Mouse |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.014
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.014
|
|
|
|
regulation of synaptic transmission glutamatergic
|
GO:0051966 |
19 |
0.014
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
50 |
0.014
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.014
|
|
|
|
localization within membrane
|
GO:0051668 |
4 |
0.014
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.014
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.014
|
|
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.014
|
|
|
|
cytokinetic process
|
GO:0032506 |
2 |
0.014
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.014
|
|
|
|
memory
|
GO:0007613 |
58 |
0.014
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.014
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.014
|
|
|
|
organelle fusion
|
GO:0048284 |
28 |
0.014
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.014
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.014
|
Fly |
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
35 |
0.014
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.014
|
|
|
|
parathyroid hormone secretion
|
GO:0035898 |
2 |
0.014
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.014
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.014
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.014
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.014
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.014
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.014
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.014
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
36 |
0.014
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.014
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.014
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.014
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.013
|
Mouse |
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.013
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.013
|
|
|
|
notochord cell development
|
GO:0060035 |
1 |
0.013
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.013
|
|
|
|
membrane fusion
|
GO:0061025 |
38 |
0.013
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.013
|
|
|
|
positive regulation of synaptic plasticity
|
GO:0031915 |
4 |
0.013
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
56 |
0.013
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.013
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.013
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.013
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.013
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.013
|
|
|
|
organism emergence from protective structure
|
GO:0071684 |
4 |
0.013
|
|
