|
|
immune effector process
|
GO:0002252 |
321 |
0.902
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.886
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.855
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.831
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.825
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.819
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.803
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.787
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.773
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.767
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.706
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.685
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.643
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.613
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.605
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.593
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.588
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.580
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.575
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.571
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.567
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.564
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.554
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.541
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.540
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.532
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.526
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.526
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.516
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.515
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.486
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.482
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.482
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.481
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.480
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.472
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.471
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.467
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.465
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.434
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.430
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.428
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.424
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.420
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.414
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.411
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.410
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.409
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.407
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.400
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.385
|
Mouse |
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.380
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.373
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.370
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.362
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.357
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.357
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.355
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.354
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.350
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.349
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.348
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.347
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.345
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.345
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.338
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.338
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.336
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.329
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.328
|
Mouse |
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.326
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.326
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.325
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.324
|
Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.323
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.322
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.314
|
Mouse |
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.313
|
Mouse |
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.313
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.306
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.302
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.301
|
Mouse |
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.296
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.296
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.292
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.292
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.290
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.289
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.289
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.287
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.283
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.282
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.282
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.282
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.275
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.265
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.264
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.263
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.257
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.256
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.254
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.252
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.250
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.250
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.246
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.245
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.245
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.245
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.243
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.242
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.241
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.238
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.238
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.235
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.232
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.232
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.230
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.230
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.229
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.229
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.228
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.226
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.224
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.223
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.220
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.219
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.218
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.217
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.216
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.216
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.215
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.214
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.213
|
Mouse |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.211
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.209
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.206
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.203
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.203
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.201
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.200
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.199
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.199
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.198
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.194
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.194
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.194
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.192
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.191
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.191
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.189
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.188
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.185
|
|
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.183
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.182
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.181
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.179
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.179
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.178
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.177
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.176
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.174
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.170
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.170
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.169
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.169
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.169
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.164
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.162
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.162
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.162
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.161
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.158
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.158
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.158
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.156
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.156
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.156
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.154
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.154
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.154
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.154
|
Mouse |
|
|
interleukin 1 beta production
|
GO:0032611 |
30 |
0.153
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.152
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.152
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.151
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.151
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.151
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.150
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.149
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.149
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.148
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.147
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.146
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.145
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.145
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.144
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.144
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.144
|
Mouse |
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.142
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.142
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.141
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.141
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.141
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.140
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.140
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.140
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.140
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.139
|
Mouse |
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.139
|
Mouse |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.138
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.136
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.135
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.133
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.133
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.132
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.132
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.132
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.130
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.130
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
25 |
0.130
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.130
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.129
|
Mouse |
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.128
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.128
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.128
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.127
|
Mouse |
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.127
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.127
|
Mouse |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.126
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.125
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.125
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.125
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.125
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.124
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.124
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.123
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.122
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.121
|
Mouse |
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.121
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.120
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.120
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.120
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.119
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.118
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.118
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.118
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.118
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.117
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.116
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.116
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.116
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.116
|
|
|
|
protein citrullination
|
GO:0018101 |
2 |
0.116
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.115
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.115
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.114
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.114
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.113
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.113
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.113
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.113
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.112
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.111
|
Mouse |
|
|
blood coagulation
|
GO:0007596 |
76 |
0.111
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.109
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.109
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.108
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.108
|
|
|
|
lamellipodium organization
|
GO:0097581 |
29 |
0.107
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.107
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.107
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.106
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.105
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.104
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.103
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.102
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.101
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.101
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.101
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.101
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.101
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.101
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.101
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.101
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.100
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.099
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.099
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.098
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
11 |
0.097
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.097
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.097
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.096
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.096
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.096
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.096
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.095
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.095
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.094
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.094
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.094
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.094
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.093
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.093
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.092
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.092
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.091
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.091
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.091
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.091
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.090
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.090
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.090
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.090
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.090
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.090
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.088
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.088
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.088
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.087
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.087
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.086
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.085
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.085
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.084
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.084
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.084
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.083
|
Mouse |
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.083
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.082
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.082
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.082
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.082
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.082
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.082
|
|
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.082
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.081
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.081
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.081
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.081
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.081
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.080
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.080
|
|
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.080
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.080
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.080
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.080
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.080
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.080
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.080
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.079
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.079
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.078
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.078
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.078
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.077
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.077
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.077
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.077
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.077
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.077
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.077
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.076
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.076
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.076
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.076
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.075
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.075
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.075
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.075
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.074
|
Mouse |
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
26 |
0.074
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.074
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.074
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.074
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.073
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.073
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.073
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.073
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.073
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.073
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.073
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.072
|
Mouse |
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.072
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.072
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.072
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.072
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.072
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.071
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.071
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.071
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.070
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.070
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.070
|
|
|
|
positive regulation of thymocyte migration
|
GO:2000412 |
2 |
0.070
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.070
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.070
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.070
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.069
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.069
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.069
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.069
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.069
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.069
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.069
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.069
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.068
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.068
|
|
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.068
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.068
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.068
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.067
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.067
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.067
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.067
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.067
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.066
|
|
|
|
visual learning
|
GO:0008542 |
44 |
0.066
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.065
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.065
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.065
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.065
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.064
|
Mouse |
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
63 |
0.064
|
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
60 |
0.064
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.064
|
|
|
|
interleukin 1 secretion
|
GO:0050701 |
16 |
0.064
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
27 |
0.063
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.063
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.063
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.063
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.062
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.062
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
41 |
0.062
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.062
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.062
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.062
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.061
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.061
|
|
|
|
metanephros development
|
GO:0001656 |
79 |
0.061
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.061
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.061
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.061
|
|
|
|
regulation of vascular endothelial growth factor production
|
GO:0010574 |
13 |
0.060
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.060
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.060
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.060
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.060
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.060
|
Mouse |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.060
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.059
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.059
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.059
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.059
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.059
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.059
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.058
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.058
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.058
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.058
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.057
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.057
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.057
|
|
|
|
eosinophil migration
|
GO:0072677 |
3 |
0.057
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.057
|
|
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.057
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.056
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.056
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.056
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.056
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.056
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.056
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.056
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.055
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.055
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.055
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.055
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.055
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.055
|
Mouse |
|
|
digestive tract development
|
GO:0048565 |
190 |
0.055
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.055
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.055
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.054
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.054
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.054
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.053
|
Mouse |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.053
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.053
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.053
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.053
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.053
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.052
|
|
|
|
regulation of hypersensitivity
|
GO:0002883 |
10 |
0.052
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.052
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.052
|
|
