Mus musculus

26 known processes

Gprc6a

G protein-coupled receptor, family C, group 6, member A

(Aliases: MGC124360)

Gprc6a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
type b pancreatic cell proliferation GO:0044342 10 0.265
regulation of hormone secretion GO:0046883 88 0.258
positive regulation of hormone secretion GO:0046887 38 0.218
nitrogen compound transport GO:0071705 271 0.181
hormone secretion GO:0046879 128 0.169
insulin secretion GO:0030073 89 0.152
regulation of secretion by cell GO:1903530 249 0.144
positive regulation of secretion by cell GO:1903532 114 0.142
peptide transport GO:0015833 133 0.138
regulation of peptide secretion GO:0002791 77 0.137
peptide secretion GO:0002790 114 0.135
blood vessel morphogenesis GO:0048514 285 0.126
response to peptide GO:1901652 136 0.119
response to insulin GO:0032868 100 0.118
regulation of peptide hormone secretion GO:0090276 75 0.115
response to peptide hormone GO:0043434 127 0.112
carbohydrate derivative biosynthetic process GO:1901137 183 0.111
regulation of peptide transport GO:0090087 91 0.108
cellular response to hormone stimulus GO:0032870 150 0.105
positive regulation of peptide secretion GO:0002793 33 0.103
cellular response to organonitrogen compound GO:0071417 145 0.099
peptide hormone secretion GO:0030072 109 0.097
cellular response to peptide hormone stimulus GO:0071375 92 0.095
response to testosterone GO:0033574 3 0.094
regulation of ion transport GO:0043269 215 0.094
Mouse
regulation of secretion GO:0051046 274 0.094
ion transmembrane transport GO:0034220 361 0.092
nucleotide metabolic process GO:0009117 332 0.089
Mouse
negative regulation of vasculature development GO:1901343 26 0.084
transmembrane transport GO:0055085 412 0.082
positive regulation of peptide hormone secretion GO:0090277 31 0.079
cellular response to peptide GO:1901653 92 0.075
positive regulation of secretion GO:0051047 130 0.075
cellular response to insulin stimulus GO:0032869 78 0.074
cellular homeostasis GO:0019725 240 0.073
cation homeostasis GO:0055080 212 0.067
negative regulation of angiogenesis GO:0016525 25 0.066
sequestering of metal ion GO:0051238 19 0.064
positive regulation of insulin secretion GO:0032024 26 0.063
response to organonitrogen compound GO:0010243 246 0.062
negative regulation of blood vessel morphogenesis GO:2000181 25 0.061
sequestering of calcium ion GO:0051208 18 0.056
regulation of hormone levels GO:0010817 211 0.056
cellular chemical homeostasis GO:0055082 215 0.055
myeloid leukocyte differentiation GO:0002573 119 0.055
anion transport GO:0006820 177 0.053
purine containing compound metabolic process GO:0072521 311 0.052
Mouse
angiogenesis GO:0001525 201 0.051
positive regulation of thymocyte migration GO:2000412 2 0.051
multicellular organismal signaling GO:0035637 91 0.050
immune response regulating signaling pathway GO:0002764 125 0.050
metal ion homeostasis GO:0055065 189 0.049
positive regulation of camp mediated signaling GO:0043950 3 0.046
regulation of cellular amine metabolic process GO:0033238 20 0.046
sensory perception GO:0007600 245 0.044
Mouse
cellular metal ion homeostasis GO:0006875 151 0.044
regulation of striated muscle cell differentiation GO:0051153 81 0.044
muscle fiber development GO:0048747 76 0.043
cellular lipid catabolic process GO:0044242 52 0.042
skeletal system development GO:0001501 356 0.042
amine metabolic process GO:0009308 45 0.041
purine ribonucleotide metabolic process GO:0009150 290 0.041
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.040
Mouse
cellular amino acid metabolic process GO:0006520 103 0.040
nucleoside phosphate metabolic process GO:0006753 338 0.039
Mouse
response to drug GO:0042493 75 0.039
leukocyte differentiation GO:0002521 342 0.038
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.038
tissue remodeling GO:0048771 102 0.038
osteoblast development GO:0002076 17 0.038
response to vitamin d GO:0033280 3 0.038
regulation of reactive oxygen species metabolic process GO:2000377 40 0.037
lipid catabolic process GO:0016042 69 0.036
neuron apoptotic process GO:0051402 142 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
Mouse
activation of immune response GO:0002253 138 0.035
ribonucleotide metabolic process GO:0009259 291 0.035
Mouse
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.033
regulation of cell activation GO:0050865 289 0.033
activation of mapk activity involved in innate immune response GO:0035419 2 0.032
glucose homeostasis GO:0042593 128 0.032
cellular ion homeostasis GO:0006873 165 0.032
transmission of nerve impulse GO:0019226 76 0.032
negative regulation of endothelial cell migration GO:0010596 4 0.031
positive regulation of protein modification process GO:0031401 299 0.031
reactive oxygen species metabolic process GO:0072593 84 0.031
positive regulation of t cell activation GO:0050870 101 0.030
immune response activating signal transduction GO:0002757 116 0.030
carbohydrate homeostasis GO:0033500 128 0.030
regulation of cellular ketone metabolic process GO:0010565 66 0.030
regulation of neuron death GO:1901214 134 0.030
neuron death GO:0070997 154 0.029
amide transport GO:0042886 138 0.029
regulation of membrane potential GO:0042391 192 0.029
calcium ion transport GO:0006816 159 0.028
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.028
Mouse
inorganic cation transmembrane transport GO:0098662 207 0.027
regulation of neuron apoptotic process GO:0043523 122 0.027
muscle cell development GO:0055001 133 0.027
regulation of cell migration GO:0030334 219 0.027
cytosolic calcium ion transport GO:0060401 48 0.027
organonitrogen compound catabolic process GO:1901565 264 0.026
Mouse
bone remodeling GO:0046849 53 0.026
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.026
ossification GO:0001503 216 0.026
heterocycle catabolic process GO:0046700 280 0.026
Mouse
cation transmembrane transport GO:0098655 266 0.025
membrane organization GO:0061024 245 0.025
striated muscle cell development GO:0055002 125 0.025
prevention of polyspermy GO:0060468 4 0.025
calcium ion transmembrane transport GO:0070588 85 0.025
response to lipopolysaccharide GO:0032496 128 0.025
dna metabolic process GO:0006259 303 0.024
carbohydrate derivative catabolic process GO:1901136 231 0.024
Mouse
response to nutrient levels GO:0031667 109 0.024
glycosyl compound metabolic process GO:1901657 246 0.024
Mouse
skeletal muscle fiber development GO:0048741 58 0.024
lymphocyte proliferation GO:0046651 164 0.023
lymphocyte differentiation GO:0030098 242 0.023
regulation of angiogenesis GO:0045765 81 0.023
regulation of establishment of protein localization GO:0070201 181 0.023
regulation of protein secretion GO:0050708 82 0.022
ribose phosphate metabolic process GO:0019693 291 0.022
Mouse
regulation of vasculature development GO:1901342 88 0.022
cellular response to organic cyclic compound GO:0071407 87 0.021
cell aging GO:0007569 35 0.021
muscle cell differentiation GO:0042692 261 0.021
regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000307 1 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
Mouse
regulation of metal ion transport GO:0010959 106 0.021
Mouse
innate immune response GO:0045087 157 0.021
positive regulation of nucleotide metabolic process GO:0045981 114 0.021
Mouse
response to extracellular stimulus GO:0009991 127 0.021
activation of innate immune response GO:0002218 56 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
Mouse
epithelial cell development GO:0002064 159 0.020
regulation of innate immune response GO:0045088 91 0.020
cellular response to growth factor stimulus GO:0071363 197 0.020
circulatory system process GO:0003013 197 0.020
positive regulation of transferase activity GO:0051347 167 0.020
carbohydrate metabolic process GO:0005975 230 0.020
pattern recognition receptor signaling pathway GO:0002221 47 0.020
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
Mouse
positive regulation of eosinophil migration GO:2000418 2 0.020
regulation of eosinophil migration GO:2000416 2 0.019
negative regulation of neuron apoptotic process GO:0043524 92 0.019
av node cell to bundle of his cell communication GO:0086067 2 0.019
exocytosis GO:0006887 121 0.019
regulation of protein kinase activity GO:0045859 232 0.019
action potential GO:0001508 78 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.018
blood circulation GO:0008015 195 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.018
glycoprotein biosynthetic process GO:0009101 89 0.018
cofactor metabolic process GO:0051186 80 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
Mouse
sensory perception of chemical stimulus GO:0007606 51 0.018
Mouse
purine containing compound catabolic process GO:0072523 213 0.018
Mouse
purine nucleoside metabolic process GO:0042278 241 0.018
Mouse
positive regulation of map kinase activity GO:0043406 84 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
Mouse
response to organic cyclic compound GO:0014070 198 0.017
extracellular matrix dependent thymocyte migration GO:0072680 1 0.017
divalent inorganic cation transport GO:0072511 178 0.017
Mouse
cellular lipid metabolic process GO:0044255 323 0.017
protein kinase b signaling GO:0043491 74 0.017
regulation of response to wounding GO:1903034 189 0.017
antigen processing and presentation GO:0019882 47 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
leukocyte migration GO:0050900 124 0.017
spermatogenesis GO:0007283 284 0.016
germ cell development GO:0007281 185 0.016
cellular response to nutrient levels GO:0031669 64 0.016
nucleoside metabolic process GO:0009116 246 0.016
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
neuronal action potential GO:0019228 54 0.016
positive regulation of cytokine production GO:0001819 174 0.016
cytoplasmic transport GO:0016482 234 0.016
tissue homeostasis GO:0001894 115 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
Mouse
cellular response to dna damage stimulus GO:0006974 207 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
Mouse
nucleoside catabolic process GO:0009164 206 0.016
Mouse
leukocyte activation involved in immune response GO:0002366 126 0.016
positive regulation of cell death GO:0010942 224 0.016
positive regulation of lymphocyte activation GO:0051251 140 0.015
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.015
cell chemotaxis GO:0060326 81 0.015
negative regulation of hormone metabolic process GO:0032351 4 0.015
regulation of cytokine production GO:0001817 266 0.015
regulation of cell cycle GO:0051726 281 0.015
myotube differentiation GO:0014902 105 0.015
regulation of ion homeostasis GO:2000021 64 0.015
single organismal cell cell adhesion GO:0016337 131 0.015
aromatic compound catabolic process GO:0019439 286 0.015
Mouse
plasma membrane organization GO:0007009 90 0.015
ear development GO:0043583 200 0.015
positive regulation of innate immune response GO:0045089 80 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
anatomical structure homeostasis GO:0060249 145 0.015
carboxylic acid transport GO:0046942 100 0.015
response to starvation GO:0042594 65 0.015
axon ensheathment GO:0008366 76 0.015
cyclic nucleotide metabolic process GO:0009187 59 0.015
t cell differentiation in thymus GO:0033077 77 0.015
macromolecule catabolic process GO:0009057 281 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
Mouse
single organism cell adhesion GO:0098602 156 0.015
synaptic transmission GO:0007268 329 0.014
cell type specific apoptotic process GO:0097285 268 0.014
positive regulation of protein secretion GO:0050714 52 0.014
actin filament based movement GO:0030048 23 0.014
calcium mediated signaling GO:0019722 46 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
skeletal muscle organ development GO:0060538 163 0.014
mapk cascade GO:0000165 281 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
Mouse
regulation of defense response GO:0031347 233 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.014
regulation of leukocyte proliferation GO:0070663 121 0.014
glucosamine containing compound metabolic process GO:1901071 3 0.014
response to monosaccharide GO:0034284 67 0.014
leukocyte chemotaxis GO:0030595 69 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
Mouse
regulation of monocyte chemotaxis GO:0090025 3 0.014
regulation of neuron differentiation GO:0045664 281 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
response to acid chemical GO:0001101 111 0.013
multi multicellular organism process GO:0044706 109 0.013
positive regulation of cell migration GO:0030335 109 0.013
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.013
regulation of t cell activation GO:0050863 170 0.013
myeloid leukocyte activation GO:0002274 83 0.013
inter male aggressive behavior GO:0002121 3 0.013
striated muscle tissue development GO:0014706 293 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
Mouse
regulation of homeostatic process GO:0032844 182 0.013
glycerolipid metabolic process GO:0046486 122 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
inflammatory response to antigenic stimulus GO:0002437 30 0.013
visual perception GO:0007601 52 0.013
myotube cell development GO:0014904 60 0.012
myelination GO:0042552 74 0.012
regulation of inflammatory response GO:0050727 147 0.012
regulation of hydrolase activity GO:0051336 246 0.012
Mouse
epithelium migration GO:0090132 63 0.012
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.012
endomembrane system organization GO:0010256 147 0.012
adaptive immune response GO:0002250 155 0.012
wnt signaling pathway GO:0016055 188 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
synapse organization GO:0050808 125 0.012
connective tissue development GO:0061448 179 0.012
heart process GO:0003015 94 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
Mouse
posttranscriptional regulation of gene expression GO:0010608 155 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
Mouse
purine ribonucleotide biosynthetic process GO:0009152 59 0.012
regulation of map kinase activity GO:0043405 120 0.012
leukocyte homeostasis GO:0001776 79 0.012
cellular response to lipid GO:0071396 145 0.012
pma inducible membrane protein ectodomain proteolysis GO:0051088 1 0.012
response to radiation GO:0009314 165 0.012
organophosphate catabolic process GO:0046434 232 0.012
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.012
endocytosis GO:0006897 168 0.012
detection of light stimulus GO:0009583 25 0.012
b cell activation GO:0042113 161 0.012
regulation of t cell proliferation GO:0042129 92 0.012
t cell differentiation GO:0030217 174 0.012
regulation of cytokine secretion GO:0050707 61 0.012
t cell activation GO:0042110 289 0.012
pancreas development GO:0031016 57 0.012
cyclic nucleotide biosynthetic process GO:0009190 44 0.012
positive regulation of cell activation GO:0050867 158 0.012
positive regulation of cytokine biosynthetic process GO:0042108 40 0.012
regulation of thymocyte migration GO:2000410 2 0.012
organic acid transport GO:0015849 101 0.011
organic cyclic compound catabolic process GO:1901361 295 0.011
Mouse
positive regulation of cell adhesion GO:0045785 80 0.011
release of sequestered calcium ion into cytosol GO:0051209 42 0.011
cellular ketone metabolic process GO:0042180 84 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
Mouse
regulation of androgen receptor signaling pathway GO:0060765 3 0.011
ras protein signal transduction GO:0007265 77 0.011
regulation of blood circulation GO:1903522 93 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
Mouse
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.011
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
monosaccharide metabolic process GO:0005996 106 0.011
positive regulation of cell development GO:0010720 237 0.011
maintenance of location GO:0051235 89 0.011
alcohol metabolic process GO:0006066 116 0.011
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.011
negative regulation of keratinocyte differentiation GO:0045617 4 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.011
fibronectin dependent thymocyte migration GO:0072681 1 0.011
regulation of lymphocyte migration GO:2000401 14 0.011
midgut development GO:0007494 4 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.010
positive regulation of inflammatory response GO:0050729 47 0.010
regulation of viral transcription GO:0046782 3 0.010
lymphocyte apoptotic process GO:0070227 54 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
apoptotic signaling pathway GO:0097190 306 0.010
positive regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000309 1 0.010
multicellular organism growth GO:0035264 161 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.010
adult behavior GO:0030534 135 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
cytokine metabolic process GO:0042107 71 0.010
negative regulation of cellular component organization GO:0051129 194 0.010
negative regulation of neuron death GO:1901215 98 0.010
response to growth factor GO:0070848 198 0.010
glucose metabolic process GO:0006006 92 0.010
guanosine containing compound catabolic process GO:1901069 144 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010
cellular response to vitamin GO:0071295 2 0.010
protein targeting to lysosome GO:0006622 2 0.010
regulation of cellular response to stress GO:0080135 159 0.010
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.010
negative regulation of muscle cell differentiation GO:0051148 33 0.010

Gprc6a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.017