Mus musculus

145 known processes

Grin2a

glutamate receptor, ionotropic, NMDA2A (epsilon 1)

(Aliases: NR2A,NMDAR2A,GluN2A)

Grin2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 329 0.999
regulation of synaptic plasticity GO:0048167 87 0.996
regulation of long term neuronal synaptic plasticity GO:0048169 19 0.966
Rat
associative learning GO:0008306 61 0.949
cognition GO:0050890 149 0.946
regulation of synaptic transmission glutamatergic GO:0051966 19 0.944
g protein coupled receptor signaling pathway GO:0007186 243 0.941
glutamate receptor signaling pathway GO:0007215 35 0.928
transmission of nerve impulse GO:0019226 76 0.926
learning GO:0007612 98 0.923
neuron neuron synaptic transmission GO:0007270 69 0.912
memory GO:0007613 58 0.885
regulation of membrane potential GO:0042391 192 0.884
long term synaptic potentiation GO:0060291 25 0.879
negative regulation of synaptic transmission glutamatergic GO:0051967 4 0.868
locomotory behavior GO:0007626 195 0.863
Mouse
learning or memory GO:0007611 148 0.862
neuromuscular process GO:0050905 99 0.853
ensheathment of neurons GO:0007272 76 0.848
cellular amino acid metabolic process GO:0006520 103 0.844
regulation of neuronal synaptic plasticity GO:0048168 30 0.841
Rat
multicellular organismal response to stress GO:0033555 62 0.840
Mouse
action potential GO:0001508 78 0.835
Rat
regulation of postsynaptic membrane potential GO:0060078 48 0.835
synaptic transmission gabaergic GO:0051932 19 0.835
adult behavior GO:0030534 135 0.831
Mouse
multicellular organismal signaling GO:0035637 91 0.811
macromolecule catabolic process GO:0009057 281 0.807
regulation of glutamate receptor signaling pathway GO:1900449 16 0.807
neuronal action potential GO:0019228 54 0.799
adult locomotory behavior GO:0008344 91 0.794
Mouse
synaptic transmission glutamatergic GO:0035249 36 0.784
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.779
membrane depolarization GO:0051899 64 0.775
axonogenesis GO:0007409 274 0.758
telencephalon development GO:0021537 186 0.718
Rat
neuromuscular process controlling balance GO:0050885 59 0.700
Mouse
protein catabolic process GO:0030163 221 0.693
neuron projection guidance GO:0097485 141 0.683
myelination GO:0042552 74 0.683
positive regulation of nervous system development GO:0051962 221 0.649
response to organic cyclic compound GO:0014070 198 0.619
Rat
regulation of ion transmembrane transporter activity GO:0032412 54 0.615
regulation of secretion by cell GO:1903530 249 0.611
divalent inorganic cation transport GO:0072511 178 0.607
fear response GO:0042596 33 0.606
Mouse
membrane organization GO:0061024 245 0.599
Mouse
regulation of neurotransmitter levels GO:0001505 87 0.592
developmental maturation GO:0021700 193 0.590
calcium ion transport GO:0006816 159 0.589
amine metabolic process GO:0009308 45 0.587
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 4 0.583
Mouse
neurotransmitter secretion GO:0007269 62 0.583
regulation of cellular amino acid metabolic process GO:0006521 5 0.580
positive regulation of synaptic transmission glutamatergic GO:0051968 8 0.565
regulation of receptor activity GO:0010469 41 0.553
regulation of cellular ketone metabolic process GO:0010565 66 0.540
cation homeostasis GO:0055080 212 0.536
inorganic cation transmembrane transport GO:0098662 207 0.533
response to amine GO:0014075 16 0.532
axon ensheathment GO:0008366 76 0.509
peristalsis GO:0030432 8 0.500
forebrain development GO:0030900 302 0.492
Rat
visual behavior GO:0007632 45 0.490
establishment of organelle localization GO:0051656 122 0.490
cellular amine metabolic process GO:0044106 44 0.487
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.486
ubiquitin dependent protein catabolic process GO:0006511 129 0.478
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.467
cellular protein catabolic process GO:0044257 155 0.465
response to nutrient levels GO:0031667 109 0.462
cellular ketone metabolic process GO:0042180 84 0.456
chemotaxis GO:0006935 247 0.448
cellular ion homeostasis GO:0006873 165 0.440
cell growth GO:0016049 130 0.436
telencephalon cell migration GO:0022029 55 0.433
muscle system process GO:0003012 141 0.418
negative regulation of phosphorus metabolic process GO:0010563 184 0.418
regulation of cell motility GO:2000145 236 0.414
olfactory learning GO:0008355 2 0.414
skeletal system development GO:0001501 356 0.414
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.412
smooth muscle contraction GO:0006939 44 0.410
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.402
cerebellum development GO:0021549 77 0.400
synapse organization GO:0050808 125 0.399
g protein coupled receptor internalization GO:0002031 3 0.398
positive regulation of cell migration GO:0030335 109 0.396
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.393
positive regulation of cellular amine metabolic process GO:0033240 5 0.390
regulation of peptide transport GO:0090087 91 0.386
potassium ion transport GO:0006813 52 0.384
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.379
exocytosis GO:0006887 121 0.378
regulation of secretion GO:0051046 274 0.377
embryonic organ morphogenesis GO:0048562 276 0.373
second messenger mediated signaling GO:0019932 73 0.373
regulation of exocytosis GO:0017157 61 0.370
regulation of hydrolase activity GO:0051336 246 0.366
regulation of synaptic transmission gabaergic GO:0032228 17 0.359
negative regulation of phosphate metabolic process GO:0045936 184 0.355
hormone secretion GO:0046879 128 0.355
nitrogen compound transport GO:0071705 271 0.351
regulation of neuron projection development GO:0010975 169 0.350
mapk cascade GO:0000165 281 0.346
regionalization GO:0003002 337 0.345
ionotropic glutamate receptor signaling pathway GO:0035235 29 0.342
regulation of transporter activity GO:0032409 57 0.341
regulation of peptide secretion GO:0002791 77 0.341
regulation of apoptotic signaling pathway GO:2001233 197 0.340
regulation of system process GO:0044057 200 0.337
glial cell differentiation GO:0010001 131 0.336
circulatory system process GO:0003013 197 0.334
organelle localization GO:0051640 179 0.318
regulation of ion transport GO:0043269 215 0.312
Mouse Rat
long term synaptic depression GO:0060292 13 0.310
feeding behavior GO:0007631 62 0.306
Mouse
anatomical structure arrangement GO:0048532 20 0.301
cellular homeostasis GO:0019725 240 0.301
carbohydrate metabolic process GO:0005975 230 0.300
metal ion homeostasis GO:0055065 189 0.299
long term memory GO:0007616 15 0.293
directional locomotion GO:0033058 3 0.293
insulin secretion GO:0030073 89 0.293
gland development GO:0048732 330 0.292
protein kinase b signaling GO:0043491 74 0.291
neuron projection extension GO:1990138 64 0.290
positive regulation of protein modification process GO:0031401 299 0.289
cell adhesion GO:0007155 329 0.287
behavioral defense response GO:0002209 28 0.287
Mouse
modification dependent protein catabolic process GO:0019941 133 0.286
glucose homeostasis GO:0042593 128 0.283
regulation of cell migration GO:0030334 219 0.282
regulation of chemotaxis GO:0050920 53 0.281
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.280
transmembrane transport GO:0055085 412 0.277
cellular macromolecule catabolic process GO:0044265 206 0.275
protein localization to nucleus GO:0034504 121 0.274
establishment of protein localization to organelle GO:0072594 118 0.271
regulation of hormone secretion GO:0046883 88 0.269
stem cell development GO:0048864 219 0.269
central nervous system neuron differentiation GO:0021953 162 0.268
response to light stimulus GO:0009416 135 0.267
gliogenesis GO:0042063 141 0.266
organonitrogen compound biosynthetic process GO:1901566 192 0.266
calcium ion homeostasis GO:0055074 127 0.266
protein localization to membrane GO:0072657 108 0.265
Mouse
opioid receptor signaling pathway GO:0038003 5 0.264
regulation of cellular catabolic process GO:0031329 242 0.263
synaptic growth at neuromuscular junction GO:0051124 6 0.262
apoptotic signaling pathway GO:0097190 306 0.262
neuron migration GO:0001764 122 0.261
visual learning GO:0008542 44 0.261
positive regulation of cell motility GO:2000147 116 0.255
synapse assembly GO:0007416 56 0.254
cellular calcium ion homeostasis GO:0006874 119 0.252
regulation of meiotic cell cycle GO:0051445 34 0.249
establishment of vesicle localization GO:0051650 81 0.247
regulation of vasculature development GO:1901342 88 0.245
pallium development GO:0021543 120 0.245
Rat
regulation of saliva secretion GO:0046877 2 0.244
response to radiation GO:0009314 165 0.243
protein oligomerization GO:0051259 67 0.241
Rat
conditioned taste aversion GO:0001661 4 0.241
establishment of spindle localization GO:0051293 19 0.240
regulation of g protein activated inward rectifier potassium channel activity GO:1900128 1 0.239
habituation GO:0046959 3 0.239
blood circulation GO:0008015 195 0.236
regulation of potassium ion transport GO:0043266 16 0.234
operant conditioning GO:0035106 2 0.233
adherens junction organization GO:0034332 28 0.233
oocyte differentiation GO:0009994 35 0.229
fertilization GO:0009566 127 0.228
regulation of actin filament based process GO:0032970 99 0.228
pole plasm assembly GO:0007315 2 0.226
purine nucleotide catabolic process GO:0006195 211 0.225
cerebral cortex development GO:0021987 86 0.225
Rat
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.224
negative regulation of phosphorylation GO:0042326 166 0.223
peptide hormone secretion GO:0030072 109 0.221
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.220
circadian rhythm GO:0007623 114 0.218
protein import into nucleus GO:0006606 95 0.218
cellular chemical homeostasis GO:0055082 215 0.218
regulation of transferase activity GO:0051338 263 0.217
cellular divalent inorganic cation homeostasis GO:0072503 127 0.217
myelination in peripheral nervous system GO:0022011 19 0.216
prevention of polyspermy GO:0060468 4 0.215
purine containing compound metabolic process GO:0072521 311 0.214
rhythmic process GO:0048511 174 0.212
Rat
regulation of cell projection organization GO:0031344 206 0.212
nucleocytoplasmic transport GO:0006913 139 0.211
cytoplasmic transport GO:0016482 234 0.210
membrane hyperpolarization GO:0060081 21 0.210
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.209
establishment or maintenance of cell polarity GO:0007163 86 0.208
peptidyl amino acid modification GO:0018193 336 0.207
positive regulation of membrane potential GO:0045838 15 0.206
Rat
nucleoside catabolic process GO:0009164 206 0.204
regulation of neurotransmitter secretion GO:0046928 29 0.204
amide transport GO:0042886 138 0.202
synaptic vesicle localization GO:0097479 59 0.202
regulation of feeding behavior GO:0060259 3 0.201
acid secretion GO:0046717 33 0.201
stem cell differentiation GO:0048863 268 0.200
regulation of neurotransmitter transport GO:0051588 35 0.200
protein homooligomerization GO:0051260 43 0.199
immune effector process GO:0002252 321 0.198
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.196
regulation of cellular amine metabolic process GO:0033238 20 0.194
stress activated protein kinase signaling cascade GO:0031098 81 0.192
negative regulation of neuron apoptotic process GO:0043524 92 0.191
epithelial cell proliferation GO:0050673 174 0.189
regulation of grooming behavior GO:2000821 4 0.188
regulation of resting membrane potential GO:0060075 3 0.188
dephosphorylation GO:0016311 129 0.188
negative regulation of molecular function GO:0044092 258 0.186
regulation of reproductive process GO:2000241 66 0.185
positive regulation of apoptotic process GO:0043065 217 0.184
response to lipopolysaccharide GO:0032496 128 0.183
regulation of sensory perception of pain GO:0051930 8 0.182
response to extracellular stimulus GO:0009991 127 0.181
regulation of circadian sleep wake cycle GO:0042749 3 0.180
circadian behavior GO:0048512 13 0.179
regulation of response to drug GO:2001023 2 0.179
sensory perception of pain GO:0019233 47 0.178
mitotic cell cycle GO:0000278 195 0.177
regulation of neuron differentiation GO:0045664 281 0.176
regulation of muscle system process GO:0090257 80 0.176
hexose metabolic process GO:0019318 98 0.173
epithelial tube morphogenesis GO:0060562 303 0.173
ameboidal type cell migration GO:0001667 128 0.173
regulation of anatomical structure size GO:0090066 178 0.171
endomembrane system organization GO:0010256 147 0.168
sensory perception GO:0007600 245 0.167
glial cell development GO:0021782 54 0.166
response to organonitrogen compound GO:0010243 246 0.166
primary amino compound metabolic process GO:1901160 8 0.164
carboxylic acid transport GO:0046942 100 0.162
adult walking behavior GO:0007628 41 0.162
modification dependent macromolecule catabolic process GO:0043632 133 0.159
forebrain cell migration GO:0021885 58 0.158
ion transmembrane transport GO:0034220 361 0.157
synaptic vesicle transport GO:0048489 57 0.155
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.155
l amino acid transport GO:0015807 32 0.155
gtp metabolic process GO:0046039 144 0.155
ribonucleoside triphosphate catabolic process GO:0009203 199 0.155
cytosolic calcium ion homeostasis GO:0051480 70 0.154
regulation of body fluid levels GO:0050878 162 0.154
regulation of angiogenesis GO:0045765 81 0.153
oocyte anterior posterior axis specification GO:0007314 2 0.153
neurotransmitter transport GO:0006836 76 0.153
placenta blood vessel development GO:0060674 31 0.151
positive regulation of protein kinase activity GO:0045860 144 0.150
axon guidance GO:0007411 141 0.148
mating GO:0007618 27 0.147
protein kinase a signaling GO:0010737 7 0.147
Mouse
metencephalon development GO:0022037 89 0.145
nuclear transport GO:0051169 139 0.145
cell recognition GO:0008037 83 0.143
positive regulation of behavior GO:0048520 40 0.142
intracellular protein transport GO:0006886 204 0.142
positive regulation of protein phosphorylation GO:0001934 242 0.142
purine ribonucleoside catabolic process GO:0046130 205 0.140
single organism nuclear import GO:1902593 95 0.140
regulation of organelle organization GO:0033043 289 0.140
purine nucleoside metabolic process GO:0042278 241 0.139
divalent inorganic cation homeostasis GO:0072507 138 0.138
somatostatin receptor signaling pathway GO:0038169 2 0.138
apical junction assembly GO:0043297 15 0.137
multicellular organismal homeostasis GO:0048871 164 0.136
ribonucleotide catabolic process GO:0009261 208 0.136
peptidyl tyrosine phosphorylation GO:0018108 143 0.135
plasma membrane organization GO:0007009 90 0.134
positive regulation of transferase activity GO:0051347 167 0.133
blastoderm segmentation GO:0007350 13 0.132
histamine induced gastric acid secretion GO:0001697 1 0.132
dendrite development GO:0016358 115 0.132
Mouse
peptidyl tyrosine modification GO:0018212 145 0.130
segmentation GO:0035282 93 0.130
cell maturation GO:0048469 127 0.130
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.128
response to ammonium ion GO:0060359 21 0.128
Rat
maternal determination of anterior posterior axis embryo GO:0008358 2 0.126
purine ribonucleotide metabolic process GO:0009150 290 0.126
regulation of metal ion transport GO:0010959 106 0.126
Mouse
positive regulation of mapk cascade GO:0043410 170 0.126
negative regulation of cellular protein metabolic process GO:0032269 247 0.125
nuclear import GO:0051170 95 0.125
cell division GO:0051301 120 0.124
cell chemotaxis GO:0060326 81 0.124
regulation of peptide hormone secretion GO:0090276 75 0.124
positive regulation of cell death GO:0010942 224 0.123
regulation of protein kinase b signaling GO:0051896 56 0.123
central nervous system neuron development GO:0021954 67 0.121
response to amphetamine GO:0001975 16 0.119
positive regulation of cytoskeleton organization GO:0051495 49 0.119
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.118
wound healing GO:0042060 157 0.118
vascular process in circulatory system GO:0003018 62 0.117
response to pain GO:0048265 26 0.117
Mouse
regulation of hormone levels GO:0010817 211 0.117
negative regulation of protein catabolic process GO:0042177 36 0.117
negative regulation of cell projection organization GO:0031345 56 0.117
calcium ion dependent exocytosis GO:0017156 35 0.116
inorganic ion transmembrane transport GO:0098660 234 0.116
negative regulation of growth GO:0045926 99 0.116
carbohydrate homeostasis GO:0033500 128 0.115
cellular modified amino acid metabolic process GO:0006575 63 0.115
cellular metal ion homeostasis GO:0006875 151 0.114
calcium mediated signaling using intracellular calcium source GO:0035584 3 0.114
positive regulation of glycolytic process GO:0045821 4 0.114
negative regulation of hydrolase activity GO:0051346 71 0.114
microtubule cytoskeleton organization GO:0000226 157 0.113
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.113
positive regulation of meiotic cell cycle GO:0051446 15 0.112
positive regulation of cell development GO:0010720 237 0.111
sodium ion transport GO:0006814 73 0.111
protein localization to organelle GO:0033365 185 0.111
cellular response to organonitrogen compound GO:0071417 145 0.111
Rat
developmental growth involved in morphogenesis GO:0060560 138 0.110
glycosyl compound catabolic process GO:1901658 206 0.110
negative regulation of intracellular signal transduction GO:1902532 167 0.110
negative regulation of secretion GO:0051048 61 0.109
locomotor rhythm GO:0045475 8 0.109
positive regulation of ras gtpase activity GO:0032320 65 0.109
regulation of protein kinase activity GO:0045859 232 0.108
heart process GO:0003015 94 0.108
innervation GO:0060384 22 0.108
urogenital system development GO:0001655 261 0.107
phenol containing compound metabolic process GO:0018958 60 0.107
purine nucleoside triphosphate catabolic process GO:0009146 203 0.107
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.107
carbohydrate derivative biosynthetic process GO:1901137 183 0.105
positive regulation of cellular catabolic process GO:0031331 148 0.105
extracellular matrix organization GO:0030198 147 0.105
positive regulation of synaptic transmission gabaergic GO:0032230 8 0.104
negative regulation of secretion by cell GO:1903531 54 0.104
oocyte construction GO:0007308 2 0.104
protein targeting GO:0006605 143 0.103
adherens junction assembly GO:0034333 22 0.103
cation transmembrane transport GO:0098655 266 0.103
regulation of erk1 and erk2 cascade GO:0070372 71 0.103
somatostatin signaling pathway GO:0038170 2 0.102
endocytosis GO:0006897 168 0.102
oocyte development GO:0048599 33 0.102
small gtpase mediated signal transduction GO:0007264 97 0.102
regulation of blood pressure GO:0008217 93 0.102
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.101
salivary gland development GO:0007431 37 0.101
positive regulation of synapse assembly GO:0051965 18 0.100
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.100
organic anion transport GO:0015711 137 0.100
gamma aminobutyric acid signaling pathway GO:0007214 8 0.099
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.099
divalent metal ion transport GO:0070838 172 0.099
cation transport GO:0006812 399 0.098
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.098
peptide transport GO:0015833 133 0.098
rhythmic behavior GO:0007622 15 0.097
myeloid leukocyte activation GO:0002274 83 0.097
skeletal system morphogenesis GO:0048705 203 0.097
nucleoside metabolic process GO:0009116 246 0.097
hormone metabolic process GO:0042445 86 0.096
single organism cell adhesion GO:0098602 156 0.095
response to inorganic substance GO:0010035 96 0.095
Rat
substrate dependent cell migration GO:0006929 18 0.095
regulation of epithelial cell proliferation GO:0050678 141 0.094
regulation of map kinase activity GO:0043405 120 0.094
protein import GO:0017038 101 0.094
regulation of cytoskeleton organization GO:0051493 122 0.094
regulation of ovulation GO:0060278 3 0.093
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.093
purine nucleoside triphosphate metabolic process GO:0009144 226 0.093
response to drug GO:0042493 75 0.092
regulation of carbohydrate metabolic process GO:0006109 75 0.092
forebrain neuron differentiation GO:0021879 52 0.092
establishment of synaptic vesicle localization GO:0097480 57 0.091
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.091
negative regulation of protein phosphorylation GO:0001933 126 0.090
positive regulation of protein kinase b signaling GO:0051897 32 0.090
activation of immune response GO:0002253 138 0.090
serotonin metabolic process GO:0042428 8 0.090
organic acid transport GO:0015849 101 0.090
hippocampus development GO:0021766 52 0.090
Rat
positive regulation of map kinase activity GO:0043406 84 0.089
mitotic cell cycle process GO:1903047 159 0.089
immune response activating signal transduction GO:0002757 116 0.088
potassium ion transmembrane transport GO:0071805 43 0.088
coagulation GO:0050817 78 0.087
reflex GO:0060004 22 0.087
establishment of neuroblast polarity GO:0045200 1 0.086
regulation of blood vessel size GO:0050880 56 0.086
angiogenesis GO:0001525 201 0.086
response to monosaccharide GO:0034284 67 0.086
organophosphate catabolic process GO:0046434 232 0.085
actin cytoskeleton reorganization GO:0031532 21 0.085
cellular nitrogen compound catabolic process GO:0044270 280 0.085
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.083
central nervous system maturation GO:0021626 6 0.082
cell cell junction organization GO:0045216 72 0.082
dopamine metabolic process GO:0042417 23 0.081
ribose phosphate metabolic process GO:0019693 291 0.081
peptide secretion GO:0002790 114 0.081
leukocyte migration GO:0050900 124 0.081
glucose metabolic process GO:0006006 92 0.080
cellular response to organic cyclic compound GO:0071407 87 0.080
Rat
regulation of response to wounding GO:1903034 189 0.079
regulation of kinase activity GO:0043549 249 0.079
regulation of actin cytoskeleton organization GO:0032956 84 0.079
grooming behavior GO:0007625 16 0.079
gonad development GO:0008406 141 0.079
notch signaling pathway GO:0007219 71 0.079
purine ribonucleoside metabolic process GO:0046128 241 0.079
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.079
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.078
glucose transport GO:0015758 56 0.078
kidney development GO:0001822 213 0.078
male courtship behavior GO:0008049 2 0.078
detection of stimulus involved in sensory perception GO:0050906 44 0.078
Mouse
erk1 and erk2 cascade GO:0070371 77 0.078
cellular extravasation GO:0045123 17 0.077
potassium ion import GO:0010107 1 0.077
hair follicle development GO:0001942 85 0.077
indole containing compound metabolic process GO:0042430 12 0.077
cellular response to temperature stimulus GO:0071502 2 0.077
nucleotide catabolic process GO:0009166 217 0.077
regulation of long term synaptic depression GO:1900452 3 0.077
protein autophosphorylation GO:0046777 61 0.076
regulation of intracellular protein transport GO:0033157 82 0.076
organic cyclic compound catabolic process GO:1901361 295 0.076
detection of external stimulus GO:0009581 61 0.076
Mouse
regulation of mapk cascade GO:0043408 248 0.075
regulation of homeostatic process GO:0032844 182 0.075
behavioral fear response GO:0001662 28 0.075
Mouse
cellular potassium ion transport GO:0071804 43 0.075
regulation of protein transport GO:0051223 163 0.075
exocrine system development GO:0035272 45 0.075
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.074
regulation of inward rectifier potassium channel activity GO:1901979 1 0.074
regulation of cell cycle GO:0051726 281 0.074
response to molecule of bacterial origin GO:0002237 143 0.074
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.074
negative regulation of apoptotic signaling pathway GO:2001234 104 0.073
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.073
granulocyte migration GO:0097530 43 0.073
anatomical structure homeostasis GO:0060249 145 0.073
nucleoside phosphate catabolic process GO:1901292 222 0.073
mesenchyme development GO:0060485 152 0.073
smoothened signaling pathway GO:0007224 105 0.072
negative regulation of hormone biosynthetic process GO:0032353 4 0.072
cerebral cortex cell migration GO:0021795 44 0.072
positive regulation of secretion GO:0051047 130 0.072
labyrinthine layer blood vessel development GO:0060716 21 0.072
response to cocaine GO:0042220 14 0.071
Rat
organic hydroxy compound metabolic process GO:1901615 203 0.070
negative regulation of response to wounding GO:1903035 77 0.070
oocyte axis specification GO:0007309 2 0.070
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 8 0.070
regulation of nucleoside metabolic process GO:0009118 130 0.069
regulation of transmembrane transport GO:0034762 128 0.069
Rat
calcium mediated signaling GO:0019722 46 0.069
cellular response to external stimulus GO:0071496 88 0.069
negative regulation of cell proliferation GO:0008285 296 0.068
cell junction organization GO:0034330 77 0.068
negative regulation of cellular amine metabolic process GO:0033239 1 0.068
cytokine production GO:0001816 319 0.068
germ cell development GO:0007281 185 0.068
organonitrogen compound catabolic process GO:1901565 264 0.067
regulation of monocyte extravasation GO:2000437 2 0.067
single fertilization GO:0007338 82 0.067
regulation of intracellular transport GO:0032386 159 0.067
dendritic spine organization GO:0097061 26 0.067
exploration behavior GO:0035640 21 0.066
compound eye development GO:0048749 1 0.066
mesenchymal cell development GO:0014031 93 0.065
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.065
skin development GO:0043588 220 0.065
nucleoside triphosphate catabolic process GO:0009143 205 0.065
regulation of long term synaptic potentiation GO:1900271 4 0.065
submandibular salivary gland formation GO:0060661 1 0.065
vesicle localization GO:0051648 86 0.064
neuromuscular synaptic transmission GO:0007274 16 0.064
morphogenesis of a branching structure GO:0001763 203 0.064
negative regulation of hormone metabolic process GO:0032351 4 0.063
negative regulation of reproductive process GO:2000242 31 0.063
microtubule based process GO:0007017 236 0.063
detection of stimulus GO:0051606 84 0.063
Mouse
small molecule biosynthetic process GO:0044283 132 0.062
muscle contraction GO:0006936 101 0.062
blood coagulation GO:0007596 76 0.062
ribonucleoside triphosphate metabolic process GO:0009199 220 0.062
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.062
hindbrain development GO:0030902 128 0.061
positive regulation of rho gtpase activity GO:0032321 41 0.061

Grin2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.169
Human
disease of anatomical entity DOID:7 0 0.169
Human
nervous system disease DOID:863 0 0.169
Human