Mus musculus

103 known processes

Grin2b

glutamate receptor, ionotropic, NMDA2B (epsilon 2)

(Aliases: NR2B,AW490526,Nmdar2b)

Grin2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 329 1.000
conditioned taste aversion GO:0001661 4 1.000
glutamate receptor signaling pathway GO:0007215 35 1.000
olfactory learning GO:0008355 2 1.000
ionotropic glutamate receptor signaling pathway GO:0035235 29 1.000
long term synaptic potentiation GO:0060291 25 1.000
positive regulation of membrane potential GO:0045838 15 1.000
regulation of synaptic plasticity GO:0048167 87 1.000
regulation of neuronal synaptic plasticity GO:0048168 30 0.999
Rat
g protein coupled glutamate receptor signaling pathway GO:0007216 3 0.999
associative learning GO:0008306 61 0.999
Mouse Rat
regulation of long term neuronal synaptic plasticity GO:0048169 19 0.999
Rat
response to morphine GO:0043278 9 0.997
male courtship behavior GO:0008049 2 0.996
social behavior GO:0035176 21 0.996
regulation of glutamate receptor signaling pathway GO:1900449 16 0.996
regulation of postsynaptic membrane potential GO:0060078 48 0.990
central nervous system maturation GO:0021626 6 0.989
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.988
regulation of receptor activity GO:0010469 41 0.986
neuron neuron synaptic transmission GO:0007270 69 0.985
synaptic vesicle localization GO:0097479 59 0.982
regulation of ion transport GO:0043269 215 0.979
Mouse Rat
synaptic growth at neuromuscular junction GO:0051124 6 0.979
activation of meiosis GO:0090427 4 0.979
positive regulation of excitatory postsynaptic membrane potential GO:2000463 14 0.976
regulation of protein serine threonine kinase activity GO:0071900 157 0.975
regulation of synaptic transmission glutamatergic GO:0051966 19 0.973
dendritic spine organization GO:0097061 26 0.969
protein localization to membrane GO:0072657 108 0.968
Mouse Rat
response to amine GO:0014075 16 0.966
Mouse Rat
positive regulation of organelle organization GO:0010638 128 0.964
adult behavior GO:0030534 135 0.963
Mouse
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.962
establishment of vesicle localization GO:0051650 81 0.962
positive regulation of mapk cascade GO:0043410 170 0.959
actin filament organization GO:0007015 113 0.958
synaptic vesicle recycling GO:0036465 19 0.953
dendritic spine morphogenesis GO:0060997 22 0.952
intraspecies interaction between organisms GO:0051703 21 0.946
neurotransmitter gated ion channel clustering GO:0072578 6 0.944
synaptic vesicle transport GO:0048489 57 0.942
response to amphetamine GO:0001975 16 0.937
Mouse Rat
positive regulation of protein phosphorylation GO:0001934 242 0.933
activation of meiosis involved in egg activation GO:0060466 2 0.932
regulation of ion transmembrane transporter activity GO:0032412 54 0.931
positive regulation of synaptic transmission glutamatergic GO:0051968 8 0.930
regulation of map kinase activity GO:0043405 120 0.927
dendritic spine development GO:0060996 30 0.923
rhythmic process GO:0048511 174 0.923
Rat
oocyte axis specification GO:0007309 2 0.923
protein localization to synapse GO:0035418 11 0.922
cation transport GO:0006812 399 0.920
pole plasm assembly GO:0007315 2 0.920
actin cytoskeleton organization GO:0030036 220 0.919
neurotransmitter secretion GO:0007269 62 0.916
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.915
protein localization to cell junction GO:1902414 3 0.915
transmembrane transport GO:0055085 412 0.914
calcium ion transport GO:0006816 159 0.907
regulation of cell projection organization GO:0031344 206 0.906
divalent inorganic cation transport GO:0072511 178 0.902
regulation of neurotransmitter levels GO:0001505 87 0.898
synapse assembly GO:0007416 56 0.897
actin polymerization or depolymerization GO:0008154 54 0.893
protein tetramerization GO:0051262 23 0.886
learning GO:0007612 98 0.885
vesicle localization GO:0051648 86 0.879
membrane organization GO:0061024 245 0.878
Mouse Rat
locomotory behavior GO:0007626 195 0.876
Mouse
regulation of transferase activity GO:0051338 263 0.870
nucleoside triphosphate metabolic process GO:0009141 230 0.870
positive regulation of protein kinase activity GO:0045860 144 0.868
multicellular organismal response to stress GO:0033555 62 0.866
synaptic transmission gabaergic GO:0051932 19 0.864
positive regulation of ion transport GO:0043270 65 0.862
Rat
positive regulation of protein modification process GO:0031401 299 0.858
long term memory GO:0007616 15 0.855
Rat
positive regulation of map kinase activity GO:0043406 84 0.853
mapk cascade GO:0000165 281 0.850
Rat
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 4 0.848
small gtpase mediated signal transduction GO:0007264 97 0.847
positive regulation of cardiac muscle cell apoptotic process GO:0010666 3 0.845
positive regulation of dendrite development GO:1900006 21 0.845
negative regulation of synaptic transmission glutamatergic GO:0051967 4 0.843
regulation of cellular catabolic process GO:0031329 242 0.837
inorganic cation transmembrane transport GO:0098662 207 0.836
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.830
response to metal ion GO:0010038 47 0.825
Rat
neuromuscular process controlling balance GO:0050885 59 0.821
Mouse
regulation of neurotransmitter secretion GO:0046928 29 0.820
visual learning GO:0008542 44 0.816
Mouse
circadian rhythm GO:0007623 114 0.814
positive regulation of nervous system development GO:0051962 221 0.811
regulation of protein kinase activity GO:0045859 232 0.807
regulation of neurotransmitter transport GO:0051588 35 0.802
regulation of t cell proliferation GO:0042129 92 0.790
gtp metabolic process GO:0046039 144 0.790
regulation of cytoskeleton organization GO:0051493 122 0.785
nucleotide catabolic process GO:0009166 217 0.780
sensory perception of pain GO:0019233 47 0.775
regulation of long term synaptic potentiation GO:1900271 4 0.775
g protein coupled receptor signaling pathway GO:0007186 243 0.769
protein oligomerization GO:0051259 67 0.761
hindbrain maturation GO:0021578 6 0.755
male mating behavior GO:0060179 6 0.751
dendrite development GO:0016358 115 0.747
Mouse
regulation of grooming behavior GO:2000821 4 0.746
establishment of organelle localization GO:0051656 122 0.740
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 3 0.738
olfactory behavior GO:0042048 7 0.734
basal protein localization GO:0045175 1 0.723
ribonucleoside triphosphate catabolic process GO:0009203 199 0.720
learning or memory GO:0007611 148 0.715
regulation of actin filament length GO:0030832 45 0.713
t cell mediated immunity GO:0002456 50 0.713
glycosyl compound catabolic process GO:1901658 206 0.707
regulation of synaptic vesicle exocytosis GO:2000300 11 0.707
regulation of respiratory gaseous exchange GO:0043576 18 0.698
positive regulation of kinase activity GO:0033674 155 0.697
regulation of membrane potential GO:0042391 192 0.695
activation of mapkk activity GO:0000186 15 0.695
adherens junction organization GO:0034332 28 0.690
inclusion body assembly GO:0070841 3 0.689
synaptic transmission glutamatergic GO:0035249 36 0.683
monosaccharide metabolic process GO:0005996 106 0.681
regulation of cellular amine metabolic process GO:0033238 20 0.680
regulation of ion transmembrane transport GO:0034765 119 0.674
gtp catabolic process GO:0006184 143 0.656
developmental maturation GO:0021700 193 0.654
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.649
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.646
regulation of synapse assembly GO:0051963 29 0.645
response to transition metal nanoparticle GO:1990267 11 0.641
Rat
response to cocaine GO:0042220 14 0.639
Rat
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway GO:0007196 3 0.627
regulation of organelle organization GO:0033043 289 0.625
regulation of long term synaptic depression GO:1900452 3 0.624
response to inorganic substance GO:0010035 96 0.622
Rat
ensheathment of neurons GO:0007272 76 0.622
activation of mapk activity GO:0000187 59 0.620
peptidyl serine modification GO:0018209 83 0.610
mitochondrion organization GO:0007005 134 0.609
purine nucleoside metabolic process GO:0042278 241 0.604
regulation of ovulation GO:0060278 3 0.588
regulation of mapk cascade GO:0043408 248 0.588
Rat
organelle fusion GO:0048284 28 0.588
regulation of transmembrane transport GO:0034762 128 0.583
establishment of synaptic vesicle localization GO:0097480 57 0.577
regulation of synaptic transmission gabaergic GO:0032228 17 0.576
protein catabolic process GO:0030163 221 0.572
Mouse
apoptotic mitochondrial changes GO:0008637 48 0.571
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.564
regulation of relaxation of muscle GO:1901077 8 0.564
positive regulation of transferase activity GO:0051347 167 0.556
cellular response to inorganic substance GO:0071241 37 0.553
Rat
locomotor rhythm GO:0045475 8 0.551
positive regulation of actin filament polymerization GO:0030838 26 0.547
regulation of hydrolase activity GO:0051336 246 0.543
regulation of neuron projection development GO:0010975 169 0.541
myelination GO:0042552 74 0.534
defecation GO:0030421 1 0.531
regulation of purine nucleotide catabolic process GO:0033121 122 0.529
establishment or maintenance of cell polarity GO:0007163 86 0.529
postsynaptic membrane organization GO:0001941 18 0.523
female gamete generation GO:0007292 74 0.518
calcium ion transmembrane transport GO:0070588 85 0.516
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.514
directional locomotion GO:0033058 3 0.512
Mouse
regulation of myelination GO:0031641 20 0.509
axonogenesis GO:0007409 274 0.509
regulation of cell division GO:0051302 76 0.504
protein autophosphorylation GO:0046777 61 0.503
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.500
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 10 0.499
regulation of nucleoside metabolic process GO:0009118 130 0.494
memory GO:0007613 58 0.492
dephosphorylation GO:0016311 129 0.491
circadian behavior GO:0048512 13 0.486
negative regulation of potassium ion transport GO:0043267 7 0.483
axon ensheathment GO:0008366 76 0.481
myelination in peripheral nervous system GO:0022011 19 0.481
guanosine containing compound metabolic process GO:1901068 144 0.478
synaptic transmission cholinergic GO:0007271 7 0.477
response to alkaloid GO:0043279 34 0.470
Rat
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.467
peptidyl serine autophosphorylation GO:0036289 1 0.462
nucleocytoplasmic transport GO:0006913 139 0.460
ion transmembrane transport GO:0034220 361 0.460
jak stat cascade GO:0007259 42 0.442
positive regulation of gtpase activity GO:0043547 85 0.441
neuron death GO:0070997 154 0.438
relaxation of cardiac muscle GO:0055119 9 0.438
regulation of cellular ketone metabolic process GO:0010565 66 0.433
endomembrane system organization GO:0010256 147 0.425
stress activated protein kinase signaling cascade GO:0031098 81 0.420
synaptic vesicle fusion to presynaptic membrane GO:0031629 3 0.401
immune response regulating signaling pathway GO:0002764 125 0.401
vesicle fusion GO:0006906 16 0.401
cognition GO:0050890 149 0.397
cellular amino acid metabolic process GO:0006520 103 0.395
macromolecule catabolic process GO:0009057 281 0.394
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.390
regulation of transporter activity GO:0032409 57 0.389
peptidyl serine phosphorylation GO:0018105 74 0.386
positive regulation of apoptotic signaling pathway GO:2001235 95 0.386
muscle tissue development GO:0060537 308 0.384
adaptive immune response GO:0002250 155 0.383
regulation of apoptotic signaling pathway GO:2001233 197 0.383
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.382
t cell cytokine production GO:0002369 10 0.380
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.377
epithelial cell proliferation GO:0050673 174 0.376
single fertilization GO:0007338 82 0.376
nuclear division GO:0000280 158 0.375
response to alcohol GO:0097305 48 0.374
telencephalon development GO:0021537 186 0.372
Rat
positive regulation of ion transmembrane transport GO:0034767 24 0.365
response to radiation GO:0009314 165 0.364
Mouse
fear response GO:0042596 33 0.363
regulation of actin cytoskeleton organization GO:0032956 84 0.360
establishment of protein localization to membrane GO:0090150 54 0.358
Mouse
habituation GO:0046959 3 0.355
response to pain GO:0048265 26 0.355
mitotic cell cycle process GO:1903047 159 0.354
cytokine production involved in immune response GO:0002367 34 0.348
peripheral nervous system development GO:0007422 53 0.346
ovulation GO:0030728 15 0.345
hindbrain development GO:0030902 128 0.341
positive regulation of apoptotic process GO:0043065 217 0.338
Mouse
neuromuscular process GO:0050905 99 0.334
cell type specific apoptotic process GO:0097285 268 0.331
regulation of protein kinase b signaling GO:0051896 56 0.327
mitotic cell cycle GO:0000278 195 0.325
regulation of actin filament polymerization GO:0030833 38 0.323
maternal determination of anterior posterior axis embryo GO:0008358 2 0.318
regulation of dendritic spine morphogenesis GO:0061001 17 0.318
immune response activating signal transduction GO:0002757 116 0.317
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.314
vesicle organization GO:0016050 60 0.314
response to ammonium ion GO:0060359 21 0.311
Rat
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.310
transmission of nerve impulse GO:0019226 76 0.309
response to calcium ion GO:0051592 20 0.305
Rat
membrane depolarization GO:0051899 64 0.304
regulation of cell motility GO:2000145 236 0.303
synapse organization GO:0050808 125 0.301
regulation of actin filament based process GO:0032970 99 0.299
protein kinase b signaling GO:0043491 74 0.297
egg activation GO:0007343 7 0.296
regulation of nuclear division GO:0051783 56 0.295
negative regulation of receptor mediated endocytosis GO:0048261 4 0.293
regulation of neuron differentiation GO:0045664 281 0.293
embryonic placenta development GO:0001892 98 0.292
regulation of purine nucleotide metabolic process GO:1900542 169 0.289
positive regulation of cell death GO:0010942 224 0.289
Mouse Rat
positive regulation of vesicle fusion GO:0031340 2 0.288
calcium mediated signaling using intracellular calcium source GO:0035584 3 0.287
regulation of calcium ion transport GO:0051924 69 0.287
Mouse
detection of stimulus GO:0051606 84 0.286
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.286
positive regulation of rac gtpase activity GO:0032855 14 0.272
muscle cell apoptotic process GO:0010657 18 0.272
regulation of jak stat cascade GO:0046425 34 0.272
cd24 biosynthetic process GO:0035724 1 0.271
cerebral cortex development GO:0021987 86 0.271
Rat
behavioral response to cocaine GO:0048148 10 0.269
aromatic compound catabolic process GO:0019439 286 0.265
ribonucleotide catabolic process GO:0009261 208 0.264
cell fate specification GO:0001708 72 0.262
protein polymerization GO:0051258 57 0.261
regulation of neuron apoptotic process GO:0043523 122 0.260
regulation of nucleotide catabolic process GO:0030811 122 0.256
protein localization to adherens junction GO:0071896 2 0.255
response to organic cyclic compound GO:0014070 198 0.255
Rat
pons development GO:0021548 13 0.254
divalent inorganic cation homeostasis GO:0072507 138 0.253
negative regulation of cellular component organization GO:0051129 194 0.252
divalent metal ion transport GO:0070838 172 0.252
positive regulation of transmembrane transport GO:0034764 29 0.248
t helper 2 cell cytokine production GO:0035745 4 0.239
mitotic nuclear division GO:0007067 48 0.239
regulation of cd24 biosynthetic process GO:2000559 1 0.239
adult locomotory behavior GO:0008344 91 0.237
Mouse
response to osmotic stress GO:0006970 21 0.232
adherens junction assembly GO:0034333 22 0.230
positive regulation of glutamate receptor signaling pathway GO:1900451 3 0.227
regulation of cellular response to stress GO:0080135 159 0.226
proteasomal protein catabolic process GO:0010498 98 0.224
single organism cell adhesion GO:0098602 156 0.223
positive regulation of cytoskeleton organization GO:0051495 49 0.223
regulation of secretion GO:0051046 274 0.222
Rat
regulation of cellular component biogenesis GO:0044087 181 0.222
sensory perception of mechanical stimulus GO:0050954 107 0.218
metanephric collecting duct development GO:0072205 7 0.217
organonitrogen compound catabolic process GO:1901565 264 0.217
response to organonitrogen compound GO:0010243 246 0.215
Mouse Rat
regulation of sensory perception of pain GO:0051930 8 0.214
Mouse
multi organism behavior GO:0051705 62 0.211
glucose homeostasis GO:0042593 128 0.210
positive regulation of nucleoside metabolic process GO:0045979 91 0.207
regulation of secretion by cell GO:1903530 249 0.206
Rat
regulation of cellular amino acid metabolic process GO:0006521 5 0.205
negative regulation of intracellular signal transduction GO:1902532 167 0.204
cellular amine metabolic process GO:0044106 44 0.204
endocytosis GO:0006897 168 0.202
negative regulation of phosphate metabolic process GO:0045936 184 0.201
regulation of cellular protein catabolic process GO:1903362 61 0.200
myeloid leukocyte migration GO:0097529 57 0.198
cytokinesis GO:0000910 17 0.198
regulation of cell cycle process GO:0010564 160 0.196
cellular response to cytokine stimulus GO:0071345 189 0.194
regulation of protein kinase a signaling GO:0010738 6 0.192
regulation of actin polymerization or depolymerization GO:0008064 45 0.192
positive regulation of calcium ion transport GO:0051928 27 0.191
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.191
cell adhesion GO:0007155 329 0.191
ribonucleoside triphosphate metabolic process GO:0009199 220 0.190
regionalization GO:0003002 337 0.190
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.187
positive regulation of cell division GO:0051781 31 0.187
mating GO:0007618 27 0.184
interleukin 5 secretion GO:0072603 2 0.184
regulation of ras gtpase activity GO:0032318 88 0.183
actin cytoskeleton reorganization GO:0031532 21 0.180
negative regulation of t cell proliferation GO:0042130 38 0.178
morphogenesis of a polarized epithelium GO:0001738 37 0.176
oocyte anterior posterior axis specification GO:0007314 2 0.176
regulation of synaptic vesicle transport GO:1902803 13 0.176
glial cell differentiation GO:0010001 131 0.174
regulation of mitochondrial membrane permeability GO:0046902 17 0.174
response to growth factor GO:0070848 198 0.173
Rat
protein kinase a signaling GO:0010737 7 0.169
apical junction assembly GO:0043297 15 0.168
neuron apoptotic process GO:0051402 142 0.167
regulation of saliva secretion GO:0046877 2 0.167
platelet aggregation GO:0070527 20 0.167
d amino acid transport GO:0042940 1 0.166
cellular response to ethanol GO:0071361 3 0.166
positive regulation of synaptic transmission gabaergic GO:0032230 8 0.166
insulin secretion GO:0030073 89 0.165
establishment of mitotic spindle orientation GO:0000132 12 0.164
camera type eye development GO:0043010 266 0.164
cytosolic calcium ion homeostasis GO:0051480 70 0.163
gonad development GO:0008406 141 0.159
b 1 b cell differentiation GO:0001923 3 0.158
neuronal action potential GO:0019228 54 0.158
negative regulation of protein localization to cell surface GO:2000009 2 0.158
amine metabolic process GO:0009308 45 0.157
negative regulation of t cell activation GO:0050868 65 0.156
regulation of erk1 and erk2 cascade GO:0070372 71 0.156
epidermal growth factor receptor signaling pathway GO:0007173 28 0.155
negative regulation of mapk cascade GO:0043409 65 0.154
regulation of short term neuronal synaptic plasticity GO:0048172 8 0.154
regulation of gtp catabolic process GO:0033124 113 0.154
grooming behavior GO:0007625 16 0.154
n methyl d aspartate receptor clustering GO:0097114 3 0.152
positive regulation of nuclear division GO:0051785 27 0.151
cytokine production GO:0001816 319 0.151
digestive tract morphogenesis GO:0048546 147 0.151
negative regulation of neuron apoptotic process GO:0043524 92 0.150
regulation of insulin receptor signaling pathway GO:0046626 21 0.149
establishment of mitotic spindle localization GO:0040001 12 0.149
positive regulation of meiotic cell cycle GO:0051446 15 0.148
negative regulation of cell activation GO:0050866 111 0.147
fertilization GO:0009566 127 0.147
negative regulation of map kinase activity GO:0043407 34 0.147
cellular metal ion homeostasis GO:0006875 151 0.146
response to oxidative stress GO:0006979 123 0.145
oocyte development GO:0048599 33 0.144
purine ribonucleotide metabolic process GO:0009150 290 0.144
negative regulation of cellular protein metabolic process GO:0032269 247 0.143
establishment of glial blood brain barrier GO:0060857 2 0.143
rhodopsin mediated signaling pathway GO:0016056 4 0.143
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.143
courtship behavior GO:0007619 5 0.143
cell recognition GO:0008037 83 0.142
prepulse inhibition GO:0060134 10 0.141
Mouse
positive regulation of ras gtpase activity GO:0032320 65 0.141
striated muscle contraction GO:0006941 45 0.141
chemotaxis GO:0006935 247 0.140
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.140
regulation of response to drug GO:2001023 2 0.139
cation transmembrane transport GO:0098655 266 0.139
nucleobase containing small molecule metabolic process GO:0055086 352 0.137
carbohydrate derivative catabolic process GO:1901136 231 0.136
respiratory gaseous exchange GO:0007585 43 0.136
purine ribonucleoside catabolic process GO:0046130 205 0.136
rhythmic behavior GO:0007622 15 0.136
ribonucleoside catabolic process GO:0042454 206 0.135
positive regulation of transporter activity GO:0032411 17 0.135
microtubule based process GO:0007017 236 0.134
guanosine containing compound catabolic process GO:1901069 144 0.132
purine nucleoside triphosphate metabolic process GO:0009144 226 0.132
chemosensory behavior GO:0007635 11 0.131
ventricular system development GO:0021591 27 0.131
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.130
response to decreased oxygen levels GO:0036293 59 0.130
cell maturation GO:0048469 127 0.129
negative regulation of protein kinase b signaling GO:0051898 18 0.129
cellular response to abiotic stimulus GO:0071214 56 0.128
negative regulation of cell adhesion GO:0007162 45 0.126
cell cell junction assembly GO:0007043 27 0.125
cell fate commitment GO:0045165 210 0.124
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.123
response to light stimulus GO:0009416 135 0.123
Mouse
positive regulation of neuron projection development GO:0010976 79 0.122
cell cell junction organization GO:0045216 72 0.121
cellular ion homeostasis GO:0006873 165 0.121
regulation of metal ion transport GO:0010959 106 0.121
Mouse
response to lipopolysaccharide GO:0032496 128 0.121
regulation of the force of heart contraction GO:0002026 17 0.118
potassium ion transport GO:0006813 52 0.118
negative regulation of antigen receptor mediated signaling pathway GO:0050858 16 0.117
regulation of sensory perception GO:0051931 8 0.117
Mouse
gliogenesis GO:0042063 141 0.116
sensory perception GO:0007600 245 0.116
somatostatin receptor signaling pathway GO:0038169 2 0.115
nucleoside metabolic process GO:0009116 246 0.115
calcium mediated signaling GO:0019722 46 0.114
metal ion homeostasis GO:0055065 189 0.113
cellular ketone metabolic process GO:0042180 84 0.113
heterocycle catabolic process GO:0046700 280 0.112
peristalsis GO:0030432 8 0.111
regulation of blood coagulation GO:0030193 28 0.111
negative regulation of molecular function GO:0044092 258 0.110
regulation of cell migration GO:0030334 219 0.110
regulation of intracellular protein transport GO:0033157 82 0.110
membrane raft organization GO:0031579 5 0.109
actin filament bundle assembly GO:0051017 40 0.109
positive regulation of neuron differentiation GO:0045666 141 0.108
cell division GO:0051301 120 0.108
negative regulation of neuron projection development GO:0010977 50 0.107
multicellular organismal homeostasis GO:0048871 164 0.107
synaptic vesicle maturation GO:0016188 7 0.107
positive regulation of protein kinase b signaling GO:0051897 32 0.107
purine containing compound metabolic process GO:0072521 311 0.106
negative regulation of cell projection organization GO:0031345 56 0.106
mitochondrial transport GO:0006839 36 0.106
response to xenobiotic stimulus GO:0009410 13 0.105
regulation of ras protein signal transduction GO:0046578 114 0.104
purine nucleotide catabolic process GO:0006195 211 0.103
cyclic nucleotide biosynthetic process GO:0009190 44 0.103
blood vessel morphogenesis GO:0048514 285 0.102
actin filament polymerization GO:0030041 44 0.099
regulation of embryonic development GO:0045995 71 0.098
adherens junction maintenance GO:0034334 1 0.098
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 11 0.097
mitochondrial membrane organization GO:0007006 26 0.096
negative regulation of apoptotic signaling pathway GO:2001234 104 0.096
peptidyl amino acid modification GO:0018193 336 0.096
b cell differentiation GO:0030183 78 0.096
regulation of feeding behavior GO:0060259 3 0.095
cytokine mediated signaling pathway GO:0019221 115 0.095
regulation of kinase activity GO:0043549 249 0.095
organophosphate catabolic process GO:0046434 232 0.094
organelle localization GO:0051640 179 0.094
negative regulation of cell proliferation GO:0008285 296 0.094
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.094
ribonucleotide metabolic process GO:0009259 291 0.093
oocyte construction GO:0007308 2 0.093
behavioral fear response GO:0001662 28 0.093
purine nucleoside triphosphate catabolic process GO:0009146 203 0.090
retina development in camera type eye GO:0060041 119 0.090
placenta blood vessel development GO:0060674 31 0.090
positive regulation of leukocyte differentiation GO:1902107 86 0.090
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.090
actomyosin structure organization GO:0031032 56 0.089
g1 s transition of mitotic cell cycle GO:0000082 57 0.089
erk1 and erk2 cascade GO:0070371 77 0.088
multi multicellular organism process GO:0044706 109 0.088
cell junction assembly GO:0034329 52 0.088
ubiquitin dependent protein catabolic process GO:0006511 129 0.087
neuromuscular synaptic transmission GO:0007274 16 0.087
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 12 0.087
protein localization to plasma membrane GO:0072659 57 0.086
b 1a b cell differentiation GO:0002337 2 0.085
cell differentiation involved in embryonic placenta development GO:0060706 26 0.085
negative regulation of epithelial cell proliferation GO:0050680 64 0.085
synaptic vesicle endocytosis GO:0048488 19 0.084
positive regulation of cell projection organization GO:0031346 95 0.084
apoptotic signaling pathway GO:0097190 306 0.084
oocyte differentiation GO:0009994 35 0.083
regulation of leukocyte proliferation GO:0070663 121 0.083
multicellular organismal signaling GO:0035637 91 0.083
glycosyl compound metabolic process GO:1901657 246 0.083
b cell activation GO:0042113 161 0.083
nitrogen compound transport GO:0071705 271 0.083
Rat
lymphocyte differentiation GO:0030098 242 0.082
purine containing compound catabolic process GO:0072523 213 0.082
cellular response to cadmium ion GO:0071276 3 0.082
purine ribonucleoside metabolic process GO:0046128 241 0.082

Grin2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
epilepsy syndrome DOID:1826 0 0.251
central nervous system disease DOID:331 0 0.251
brain disease DOID:936 0 0.251
electroclinical syndrome DOID:0050701 0 0.251
disease of anatomical entity DOID:7 0 0.251
nervous system disease DOID:863 0 0.251