|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
34 |
1.000
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
6 |
0.999
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.996
|
|
|
|
wnt signaling pathway involved in somitogenesis
|
GO:0090244 |
4 |
0.995
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.995
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.995
|
Rat Fly |
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
31 |
0.995
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.993
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.992
|
|
|
|
formation of radial glial scaffolds
|
GO:0021943 |
4 |
0.991
|
|
|
|
genetic imprinting
|
GO:0071514 |
27 |
0.990
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.987
|
Mouse Rat Fly |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.987
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.985
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.985
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.984
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.973
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.973
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.972
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.972
|
|
|
|
positive regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000060 |
8 |
0.967
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.966
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.965
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.964
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.962
|
Fly |
|
|
protein targeting
|
GO:0006605 |
143 |
0.956
|
Human |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.956
|
Rat Fly |
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.953
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.950
|
Rat Fly |
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.944
|
|
|
|
canonical wnt signaling pathway involved in regulation of cell proliferation
|
GO:0044340 |
3 |
0.943
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.943
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.937
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.937
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.937
|
Rat Fly |
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
30 |
0.936
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.935
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.934
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.933
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.933
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.932
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.929
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.927
|
Fly |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.927
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.927
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.925
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.925
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.923
|
Rat Fly |
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.920
|
|
|
|
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis
|
GO:2000166 |
1 |
0.919
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.915
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.914
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.914
|
Rat Fly |
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.910
|
Rat Fly |
|
|
digestive tract development
|
GO:0048565 |
190 |
0.908
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.905
|
Fly |
|
|
oogenesis
|
GO:0048477 |
56 |
0.904
|
Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.899
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.898
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.896
|
Worm |
|
|
nuclear transport
|
GO:0051169 |
139 |
0.893
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.893
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.889
|
Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.885
|
Rat Fly |
|
|
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis
|
GO:2000148 |
1 |
0.885
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.885
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.881
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
33 |
0.876
|
Worm |
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.873
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.873
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.873
|
Rat Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.870
|
Mouse |
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.868
|
|
|
|
regulation of planar cell polarity pathway involved in outflow tract morphogenesis
|
GO:2000163 |
1 |
0.866
|
|
|
|
canonical wnt signaling pathway involved in heart development
|
GO:0061316 |
3 |
0.866
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.862
|
Worm Fly |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.857
|
Human Rat Fly |
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.856
|
|
|
|
positive regulation of cell proliferation involved in heart valve morphogenesis
|
GO:0003251 |
1 |
0.852
|
|
|
|
hindbrain radial glia guided cell migration
|
GO:0021932 |
12 |
0.851
|
|
|
|
regulation of axon extension
|
GO:0030516 |
43 |
0.851
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
13 |
0.849
|
Fly |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.848
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.846
|
Mouse |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.846
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.840
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.839
|
Human Worm |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.838
|
Human |
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.834
|
|
|
|
canonical wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation
|
GO:0061324 |
2 |
0.828
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.827
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.826
|
Fly |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.824
|
Worm |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.819
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.816
|
Rat Fly |
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.816
|
Worm |
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.809
|
|
|
|
schwann cell proliferation
|
GO:0014010 |
2 |
0.807
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.801
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.801
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
20 |
0.799
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.796
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.796
|
Rat Fly |
|
|
centromeric sister chromatid cohesion
|
GO:0070601 |
3 |
0.791
|
|
|
|
cerebellum morphogenesis
|
GO:0021587 |
42 |
0.791
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.788
|
Worm |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.786
|
Human |
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.784
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.777
|
Worm Fly |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.773
|
Fly |
|
|
peptide transport
|
GO:0015833 |
133 |
0.773
|
|
|
|
negative regulation of planar cell polarity pathway involved in heart morphogenesis
|
GO:2000160 |
1 |
0.772
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.770
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.769
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.767
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.757
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
27 |
0.756
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.755
|
Worm Fly |
|
|
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis
|
GO:2000162 |
1 |
0.755
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.748
|
|
|
|
cytoplasmic microtubule organization
|
GO:0031122 |
14 |
0.747
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.746
|
|
|
|
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis
|
GO:2000149 |
1 |
0.746
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.742
|
Rat Fly |
|
|
regionalization
|
GO:0003002 |
337 |
0.738
|
Fly |
|
|
axis elongation involved in somitogenesis
|
GO:0090245 |
4 |
0.737
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.734
|
Fly |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.732
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.729
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.723
|
|
|
|
negative regulation of platelet derived growth factor receptor beta signaling pathway
|
GO:2000587 |
2 |
0.721
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.720
|
Rat Fly |
|
|
regulation of chromosome segregation
|
GO:0051983 |
21 |
0.715
|
Fly |
|
|
regulation of peptidyl threonine phosphorylation
|
GO:0010799 |
12 |
0.715
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.706
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.704
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.702
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.702
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.700
|
Rat |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.700
|
Human |
|
|
axon guidance
|
GO:0007411 |
141 |
0.700
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.695
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
25 |
0.694
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.688
|
Human Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.686
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.685
|
Rat Fly |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.684
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.683
|
Human |
|
|
protein processing
|
GO:0016485 |
163 |
0.682
|
|
|
|
germline cell cycle switching mitotic to meiotic cell cycle
|
GO:0051729 |
1 |
0.680
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.675
|
Human |
|
|
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000058 |
14 |
0.668
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.667
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
50 |
0.667
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.666
|
Fly |
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
23 |
0.661
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.656
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.645
|
|
|
|
negative regulation of dna templated transcription elongation
|
GO:0032785 |
6 |
0.639
|
|
|
|
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
|
GO:0061350 |
2 |
0.635
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.630
|
Fly |
|
|
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis
|
GO:2000164 |
1 |
0.630
|
|
|
|
positive regulation of ubiquitin protein transferase activity
|
GO:0051443 |
4 |
0.629
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.628
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.624
|
Fly |
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.615
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.615
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.614
|
Human Mouse |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.605
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.605
|
Mouse |
|
|
embryonic axis specification
|
GO:0000578 |
30 |
0.605
|
|
|
|
metanephric mesenchyme morphogenesis
|
GO:0072133 |
4 |
0.604
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.603
|
|
|
|
regulation of platelet derived growth factor receptor beta signaling pathway
|
GO:2000586 |
2 |
0.601
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.600
|
|
|
|
regulation of phospholipase a2 activity
|
GO:0032429 |
3 |
0.599
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.597
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.586
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.585
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.584
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
15 |
0.579
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.578
|
Worm |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.575
|
|
|
|
heart field specification
|
GO:0003128 |
6 |
0.575
|
|
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
2 |
0.572
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.571
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.566
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.565
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.564
|
Human |
|
|
cerebellum development
|
GO:0021549 |
77 |
0.563
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.562
|
Human Mouse |
|
|
cell fate specification
|
GO:0001708 |
72 |
0.560
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.558
|
Fly |
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
7 |
0.558
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.557
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.553
|
Human Mouse |
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.549
|
Mouse |
|
|
female gamete generation
|
GO:0007292 |
74 |
0.543
|
Fly |
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.540
|
Mouse |
|
|
cell proliferation involved in heart valve morphogenesis
|
GO:0003249 |
1 |
0.539
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.539
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.538
|
Human |
|
|
negative regulation of cell projection organization
|
GO:0031345 |
56 |
0.537
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.537
|
Human |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.535
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.534
|
|
|
|
catenin import into nucleus
|
GO:0035411 |
6 |
0.531
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.530
|
Fly |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.526
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.524
|
Worm Fly |
|
|
hindbrain morphogenesis
|
GO:0021575 |
46 |
0.523
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.522
|
Mouse |
|
|
regulation of planar cell polarity pathway involved in heart morphogenesis
|
GO:2000159 |
1 |
0.518
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.517
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.515
|
Rat Fly |
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.508
|
Human |
|
|
response to cholesterol
|
GO:0070723 |
4 |
0.507
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.504
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.502
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.502
|
Worm Fly |
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.498
|
Fly |
|
|
neuroblast fate commitment
|
GO:0014017 |
1 |
0.498
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.495
|
|
|
|
lateral line system development
|
GO:0048925 |
1 |
0.493
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
30 |
0.493
|
Human |
|
|
negative regulation of planar cell polarity pathway involved in neural tube closure
|
GO:2000168 |
1 |
0.490
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.490
|
Human Fly |
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.485
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.483
|
|
|
|
regulation of extent of cell growth
|
GO:0061387 |
52 |
0.477
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.476
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.476
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.476
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.474
|
Fly |
|
|
regulation of synapse assembly
|
GO:0051963 |
29 |
0.474
|
Fly |
|
|
polarity specification of proximal distal axis
|
GO:0010085 |
2 |
0.466
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.459
|
Mouse |
|
|
regulation of planar cell polarity pathway involved in neural tube closure
|
GO:2000167 |
1 |
0.455
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.455
|
Worm |
|
|
metencephalon development
|
GO:0022037 |
89 |
0.453
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.453
|
Worm |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.453
|
|
|
|
intracellular lipid transport
|
GO:0032365 |
3 |
0.452
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
63 |
0.451
|
|
|
|
regulation of presynaptic membrane organization
|
GO:1901629 |
3 |
0.448
|
|
|
|
planar cell polarity pathway involved in pericardium morphogenesis
|
GO:0061354 |
2 |
0.448
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.447
|
Fly |
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
31 |
0.447
|
Mouse |
|
|
wnt signaling pathway involved in forebrain neuroblast division
|
GO:0021874 |
2 |
0.446
|
|
|
|
embryonic skeletal joint development
|
GO:0072498 |
13 |
0.446
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
23 |
0.443
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.441
|
|
|
|
axon cargo transport
|
GO:0008088 |
33 |
0.437
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.434
|
Mouse |
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.430
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.429
|
Human |
|
|
forebrain development
|
GO:0030900 |
302 |
0.423
|
Human |
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.422
|
|
|
|
canonical wnt signaling pathway involved in negative regulation of apoptotic process
|
GO:0044336 |
4 |
0.421
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.418
|
Fly |
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.417
|
|
|
|
vesicle transport along microtubule
|
GO:0047496 |
9 |
0.417
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.415
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.412
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.412
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.411
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.409
|
|
|
|
regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis
|
GO:2000161 |
1 |
0.404
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.402
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
3 |
0.402
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.398
|
Human |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.397
|
|
|
|
planar cell polarity pathway involved in cardiac right atrium morphogenesis
|
GO:0061349 |
2 |
0.396
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.396
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.395
|
Human |
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.394
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.394
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.389
|
Fly |
|
|
mesoderm morphogenesis
|
GO:0048332 |
64 |
0.389
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.388
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.387
|
Human |
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.386
|
Rat |
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.384
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.384
|
|
|
|
cell cycle switching mitotic to meiotic cell cycle
|
GO:0051728 |
1 |
0.383
|
|
|
|
long term memory
|
GO:0007616 |
15 |
0.383
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.383
|
|
|
|
filopodium assembly
|
GO:0046847 |
19 |
0.383
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.381
|
Mouse |
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.381
|
|
|
|
nephrogenic mesenchyme morphogenesis
|
GO:0072134 |
2 |
0.381
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.379
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.379
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.378
|
Human |
|
|
canonical wnt signaling pathway involved in positive regulation of apoptotic process
|
GO:0044337 |
3 |
0.376
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.374
|
|
|
|
sensory system development
|
GO:0048880 |
3 |
0.374
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.370
|
|
|
|
negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
|
GO:2000151 |
1 |
0.368
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.368
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.367
|
Human |
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.367
|
Fly |
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.366
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.362
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.360
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
25 |
0.359
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.355
|
Human |
|
|
mitochondrial transport
|
GO:0006839 |
36 |
0.355
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.353
|
Human Mouse |
|
|
respiratory system development
|
GO:0060541 |
190 |
0.353
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
37 |
0.352
|
Worm Fly |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.351
|
|
|
|
regulation of smoothened signaling pathway
|
GO:0008589 |
58 |
0.347
|
Fly |
|
|
molting cycle
|
GO:0042303 |
90 |
0.347
|
Fly |
|
|
cardiac right atrium morphogenesis
|
GO:0003213 |
3 |
0.346
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.344
|
Mouse Rat |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.343
|
Human |
|
|
habituation
|
GO:0046959 |
3 |
0.341
|
Fly |
|
|
synapse assembly
|
GO:0007416 |
56 |
0.338
|
Fly |
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
9 |
0.337
|
Fly |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.337
|
Mouse Rat Fly |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.332
|
Human Mouse |
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.328
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.325
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.324
|
Human |
|
|
genitalia morphogenesis
|
GO:0035112 |
11 |
0.322
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.320
|
|
|
|
apoptotic cell clearance
|
GO:0043277 |
17 |
0.318
|
Worm |
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.318
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.318
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.317
|
Human Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.316
|
|
|
|
regulation of wnt signaling pathway planar cell polarity pathway
|
GO:2000095 |
10 |
0.316
|
|
|
|
secondary heart field specification
|
GO:0003139 |
6 |
0.314
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.314
|
Mouse |
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.314
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.313
|
|
|
|
microtubule based transport
|
GO:0010970 |
50 |
0.312
|
|
|
|
regulation of planar cell polarity pathway involved in pericardium morphogenesis
|
GO:2000165 |
1 |
0.311
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.311
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.310
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.309
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.308
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.306
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.305
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.304
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.303
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.303
|
Human |
|
|
lipid localization
|
GO:0010876 |
126 |
0.302
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.301
|
|
|
|
axial mesoderm development
|
GO:0048318 |
8 |
0.301
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.300
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.297
|
Mouse |
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.296
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.295
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.295
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
17 |
0.294
|
Mouse |
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.292
|
Mouse |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.292
|
Human Mouse |
|
|
canonical wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development
|
GO:0061310 |
1 |
0.291
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.290
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.290
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.290
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.289
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.287
|
Mouse |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.287
|
Human |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.287
|
Human Mouse |
|
|
canonical wnt signaling pathway involved in neural crest cell differentiation
|
GO:0044335 |
1 |
0.285
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.285
|
Human |
|
|
regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
|
GO:2000150 |
1 |
0.285
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.285
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.284
|
|
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.283
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.282
|
Mouse Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.281
|
Human |
|
|
nuclear import
|
GO:0051170 |
95 |
0.277
|
Human |
|
|
sister chromatid cohesion
|
GO:0007062 |
12 |
0.277
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.277
|
Mouse |
|
|
regulation of cell proliferation involved in outflow tract morphogenesis
|
GO:1901963 |
2 |
0.277
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.276
|
|
|
|
planar cell polarity pathway involved in outflow tract morphogenesis
|
GO:0061347 |
2 |
0.275
|
|
|
|
receptor mediated endocytosis of low density lipoprotein particle involved in cholesterol transport
|
GO:0090118 |
1 |
0.275
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.274
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.274
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.274
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.273
|
Rat Fly |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.273
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.273
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.269
|
Rat Fly |
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.268
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.268
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.267
|
Human |
|
|
chromatin organization
|
GO:0006325 |
206 |
0.266
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.266
|
Human |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.265
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.264
|
|
|
|
regulation of centromeric sister chromatid cohesion
|
GO:0070602 |
3 |
0.264
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.261
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.259
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.258
|
Fly |
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.257
|
Human |
|
|
cell cycle switching
|
GO:0060184 |
1 |
0.255
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.255
|
|
|
|
forebrain radial glial cell differentiation
|
GO:0021861 |
4 |
0.254
|
|
|
|
regulation of lipid transport
|
GO:0032368 |
36 |
0.254
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.253
|
Rat Fly |
|
|
kidney mesenchyme morphogenesis
|
GO:0072131 |
4 |
0.252
|
|
|
|
spindle localization
|
GO:0051653 |
22 |
0.252
|
Worm |
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.252
|
|
|
|
organelle transport along microtubule
|
GO:0072384 |
14 |
0.252
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.251
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.249
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.248
|
|
|
|
protein targeting to vacuole
|
GO:0006623 |
3 |
0.248
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.247
|
|
|
|
axial mesoderm formation
|
GO:0048320 |
3 |
0.246
|
|
|
|
regulation of protein depolymerization
|
GO:1901879 |
26 |
0.244
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.241
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.240
|
|
|
|
midgut development
|
GO:0007494 |
4 |
0.239
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.238
|
|
|
|
germ line stem cell division
|
GO:0042078 |
2 |
0.237
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.236
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.235
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.235
|
Human |
|
|
somite development
|
GO:0061053 |
81 |
0.235
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
41 |
0.235
|
Fly |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.234
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.234
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.234
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.233
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.233
|
|
|
|
regulation of non canonical wnt signaling pathway
|
GO:2000050 |
12 |
0.233
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.232
|
Mouse |
|
|
cell division
|
GO:0051301 |
120 |
0.231
|
Fly |
|
|
protein localization to vacuole
|
GO:0072665 |
4 |
0.231
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.230
|
Human |
|
|
muscle cell development
|
GO:0055001 |
133 |
0.229
|
Mouse |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.229
|
|
|
|
multi organism reproductive behavior
|
GO:0044705 |
29 |
0.228
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.228
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.226
|
Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.224
|
Human |
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.224
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.223
|
Worm Fly |
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.223
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.222
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.220
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.220
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.220
|
|
|
|
foregut regionalization
|
GO:0060423 |
3 |
0.219
|
|
|
|
neuron maturation
|
GO:0042551 |
29 |
0.219
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.219
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.218
|
Human Mouse |
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.216
|
|
|
|
attachment of spindle microtubules to kinetochore
|
GO:0008608 |
4 |
0.215
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.215
|
|
|
|
nuclear transcribed mrna catabolic process deadenylation dependent decay
|
GO:0000288 |
12 |
0.214
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.213
|
Mouse |
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.213
|
|
|
|
defecation
|
GO:0030421 |
1 |
0.213
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.212
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.212
|
Human |
|
|
cell differentiation in hindbrain
|
GO:0021533 |
24 |
0.210
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.208
|
|
|
|
genitalia development
|
GO:0048806 |
37 |
0.208
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.206
|
Fly |
|
|
pigment accumulation
|
GO:0043476 |
1 |
0.206
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.206
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
33 |
0.205
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.205
|
Worm Fly |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.204
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.203
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.201
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.200
|
|
|
|
learning
|
GO:0007612 |
98 |
0.199
|
Fly |
|
|
negative regulation of peptidyl serine phosphorylation
|
GO:0033137 |
10 |
0.198
|
|
|
|
directional locomotion
|
GO:0033058 |
3 |
0.198
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.197
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.197
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.197
|
Worm Fly |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.197
|
Human Mouse |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.196
|
Human Mouse |
|
|
exocytosis
|
GO:0006887 |
121 |
0.196
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.194
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.194
|
Human |
