Mus musculus

123 known processes

Guca1a

guanylate cyclase activator 1a (retina)

(Aliases: GC-A,mGCAP1,Guca1,Gcap1)

Guca1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
retinal cone cell development GO:0046549 8 0.229
regulation of body fluid levels GO:0050878 162 0.106
carbohydrate metabolic process GO:0005975 230 0.106
regulation of proteolysis GO:0030162 164 0.088
phototransduction GO:0007602 17 0.069
detection of stimulus GO:0051606 84 0.066
wound healing GO:0042060 157 0.064
cytokine production GO:0001816 319 0.063
photoreceptor cell development GO:0042461 40 0.057
cellular chemical homeostasis GO:0055082 215 0.057
cell type specific apoptotic process GO:0097285 268 0.056
skeletal system development GO:0001501 356 0.053
eye photoreceptor cell development GO:0042462 31 0.053
lymphocyte mediated immunity GO:0002449 139 0.049
cell killing GO:0001906 67 0.048
hemostasis GO:0007599 78 0.044
response to light stimulus GO:0009416 135 0.044
glutamate receptor signaling pathway GO:0007215 35 0.043
organelle assembly GO:0070925 177 0.043
rhodopsin mediated signaling pathway GO:0016056 4 0.043
protein maturation GO:0051604 176 0.042
photoreceptor cell differentiation GO:0046530 52 0.042
regulation of system process GO:0044057 200 0.041
organic anion transport GO:0015711 137 0.041
detection of light stimulus GO:0009583 25 0.041
nitrogen compound transport GO:0071705 271 0.040
dna modification GO:0006304 50 0.040
carbohydrate derivative biosynthetic process GO:1901137 183 0.040
regulation of secretion by cell GO:1903530 249 0.039
anion transport GO:0006820 177 0.039
detection of abiotic stimulus GO:0009582 60 0.039
cellular lipid metabolic process GO:0044255 323 0.038
visual perception GO:0007601 52 0.038
sensory perception of umami taste GO:0050917 4 0.038
immune effector process GO:0002252 321 0.037
alcohol metabolic process GO:0006066 116 0.036
coagulation GO:0050817 78 0.036
oxidation reduction process GO:0055114 342 0.036
organonitrogen compound biosynthetic process GO:1901566 192 0.035
ossification GO:0001503 216 0.035
microtubule based process GO:0007017 236 0.035
eye photoreceptor cell differentiation GO:0001754 41 0.034
developmental maturation GO:0021700 193 0.034
dna metabolic process GO:0006259 303 0.034
inflammatory response GO:0006954 244 0.034
negative regulation of protein metabolic process GO:0051248 282 0.033
response to radiation GO:0009314 165 0.033
protein catabolic process GO:0030163 221 0.033
response to inorganic substance GO:0010035 96 0.032
transmembrane transport GO:0055085 412 0.032
defense response to other organism GO:0098542 197 0.031
response to organonitrogen compound GO:0010243 246 0.031
spermatogenesis GO:0007283 284 0.031
gland development GO:0048732 330 0.031
circulatory system process GO:0003013 197 0.030
organelle localization GO:0051640 179 0.030
multicellular organismal signaling GO:0035637 91 0.029
methylation GO:0032259 134 0.029
negative regulation of cellular protein metabolic process GO:0032269 247 0.029
retinal cone cell differentiation GO:0042670 8 0.028
regulation of cell activation GO:0050865 289 0.028
dna alkylation GO:0006305 43 0.028
leukocyte mediated cytotoxicity GO:0001909 62 0.027
anatomical structure homeostasis GO:0060249 145 0.027
blood coagulation GO:0007596 76 0.027
camera type eye development GO:0043010 266 0.027
cellular ketone metabolic process GO:0042180 84 0.027
macromolecule methylation GO:0043414 120 0.027
male gamete generation GO:0048232 285 0.027
cellular amino acid metabolic process GO:0006520 103 0.026
cellular homeostasis GO:0019725 240 0.026
regulation of protein processing GO:0070613 96 0.026
innate immune response GO:0045087 157 0.026
sperm motility GO:0030317 47 0.026
organic acid transport GO:0015849 101 0.026
lipid transport GO:0006869 98 0.025
macromolecule glycosylation GO:0043413 55 0.025
muscle contraction GO:0006936 101 0.025
regulation of blood circulation GO:1903522 93 0.025
cellular amine metabolic process GO:0044106 44 0.025
protein glycosylation GO:0006486 55 0.025
protein processing GO:0016485 163 0.025
regulation of neuron differentiation GO:0045664 281 0.024
regulation of endopeptidase activity GO:0052548 89 0.024
lipid biosynthetic process GO:0008610 179 0.024
steroid metabolic process GO:0008202 119 0.023
skeletal system morphogenesis GO:0048705 203 0.023
regulation of cellular ketone metabolic process GO:0010565 66 0.023
regulation of transferase activity GO:0051338 263 0.023
regulation of vesicle mediated transport GO:0060627 139 0.023
myeloid cell differentiation GO:0030099 233 0.023
retina development in camera type eye GO:0060041 119 0.023
cellular metal ion homeostasis GO:0006875 151 0.022
acetylcholine transport GO:0015870 2 0.022
action potential GO:0001508 78 0.022
purine nucleotide biosynthetic process GO:0006164 65 0.022
macromolecule catabolic process GO:0009057 281 0.022
activation of adenylate cyclase activity GO:0007190 4 0.022
dna methylation GO:0006306 43 0.022
g protein coupled receptor signaling pathway GO:0007186 243 0.022
myotube differentiation GO:0014902 105 0.021
digestion GO:0007586 40 0.021
fucosylation GO:0036065 9 0.021
response to organic cyclic compound GO:0014070 198 0.021
central nervous system neuron differentiation GO:0021953 162 0.021
regulation of peptidase activity GO:0052547 96 0.021
reactive nitrogen species metabolic process GO:2001057 0 0.021
regulation of cytokine production GO:0001817 266 0.021
fatty acid metabolic process GO:0006631 121 0.021
hexose metabolic process GO:0019318 98 0.020
positive regulation of transferase activity GO:0051347 167 0.020
positive regulation of cytokine production GO:0001819 174 0.020
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.020
negative regulation of immune system process GO:0002683 209 0.020
endocytosis GO:0006897 168 0.020
glycosylation GO:0070085 62 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
positive regulation of kinase activity GO:0033674 155 0.020
interspecies interaction between organisms GO:0044419 83 0.020
leukocyte mediated immunity GO:0002443 174 0.020
epithelial cell development GO:0002064 159 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
cellular response to lipid GO:0071396 145 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
reactive oxygen species biosynthetic process GO:1903409 8 0.019
regulation of chloride transport GO:2001225 2 0.019
regulation of secretion GO:0051046 274 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.019
regulation of lymphocyte mediated immunity GO:0002706 84 0.019
muscle cell differentiation GO:0042692 261 0.019
detection of external stimulus GO:0009581 61 0.019
regulation of blood vessel size GO:0050880 56 0.019
t cell activation GO:0042110 289 0.019
photoreceptor cell maintenance GO:0045494 19 0.018
disruption by host of symbiont cells GO:0051852 11 0.018
activation of mapk activity GO:0000187 59 0.018
regulation of response to wounding GO:1903034 189 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
establishment of organelle localization GO:0051656 122 0.018
nucleotide biosynthetic process GO:0009165 78 0.018
organophosphate biosynthetic process GO:0090407 122 0.018
spermatid development GO:0007286 108 0.017
ion transmembrane transport GO:0034220 361 0.017
purine ribonucleotide biosynthetic process GO:0009152 59 0.017
camera type eye photoreceptor cell differentiation GO:0060219 15 0.017
limb development GO:0060173 166 0.017
lymphocyte proliferation GO:0046651 164 0.017
monosaccharide metabolic process GO:0005996 106 0.017
amine metabolic process GO:0009308 45 0.017
embryonic limb morphogenesis GO:0030326 126 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
glycoprotein metabolic process GO:0009100 116 0.017
positive regulation of cell death GO:0010942 224 0.017
regulation of cellular protein catabolic process GO:1903362 61 0.017
sensory perception GO:0007600 245 0.017
regulation of membrane potential GO:0042391 192 0.017
defense response to bacterium GO:0042742 119 0.016
leukocyte differentiation GO:0002521 342 0.016
sensory organ morphogenesis GO:0090596 242 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
nucleotide metabolic process GO:0009117 332 0.016
cellular response to abiotic stimulus GO:0071214 56 0.016
cellular ion homeostasis GO:0006873 165 0.016
fat soluble vitamin biosynthetic process GO:0042362 4 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
carboxylic acid transport GO:0046942 100 0.016
regulation of hormone levels GO:0010817 211 0.016
regulation of cellular amino acid metabolic process GO:0006521 5 0.016
muscle tissue development GO:0060537 308 0.016
negative regulation of cell proliferation GO:0008285 296 0.015
platelet activation GO:0030168 40 0.015
regulation of anatomical structure size GO:0090066 178 0.015
cellular component assembly involved in morphogenesis GO:0010927 139 0.015
negative regulation of cell activation GO:0050866 111 0.015
heart contraction GO:0060047 93 0.015
homeostasis of number of cells GO:0048872 210 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
phagocytosis GO:0006909 66 0.015
skeletal muscle organ development GO:0060538 163 0.015
regulation of blood pressure GO:0008217 93 0.015
glycerolipid metabolic process GO:0046486 122 0.015
vitamin a metabolic process GO:0006776 2 0.015
negative regulation of growth GO:0045926 99 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
organic hydroxy compound transport GO:0015850 93 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
cellular response to lipopolysaccharide GO:0071222 77 0.015
negative regulation of molecular function GO:0044092 258 0.015
fibroblast migration GO:0010761 21 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
appendage development GO:0048736 166 0.015
regulation of cellular amine metabolic process GO:0033238 20 0.015
regulation of defense response GO:0031347 233 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
respiratory tube development GO:0030323 167 0.014
limb morphogenesis GO:0035108 149 0.014
regulation of feeding behavior GO:0060259 3 0.014
monocarboxylic acid transport GO:0015718 44 0.014
activation of immune response GO:0002253 138 0.014
sterol metabolic process GO:0016125 58 0.014
cardiac muscle contraction GO:0060048 32 0.014
cellular response to molecule of bacterial origin GO:0071219 83 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
regulation of protein kinase activity GO:0045859 232 0.014
cofactor transport GO:0051181 4 0.014
cell maturation GO:0048469 127 0.014
vitamin metabolic process GO:0006766 23 0.014
muscle system process GO:0003012 141 0.014
vesicle organization GO:0016050 60 0.014
negative regulation of response to wounding GO:1903035 77 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
glucose homeostasis GO:0042593 128 0.014
response to amine GO:0014075 16 0.014
detection of visible light GO:0009584 14 0.014
blood vessel morphogenesis GO:0048514 285 0.014
connective tissue development GO:0061448 179 0.014
smooth muscle contraction GO:0006939 44 0.014
retinoid metabolic process GO:0001523 24 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.013
response to acid chemical GO:0001101 111 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
developmental pigmentation GO:0048066 40 0.013
regulation of plasminogen activation GO:0010755 4 0.013
regulation of cell killing GO:0031341 40 0.013
small molecule biosynthetic process GO:0044283 132 0.013
calcium ion homeostasis GO:0055074 127 0.013
regulation of protein secretion GO:0050708 82 0.013
embryonic digit morphogenesis GO:0042733 56 0.013
multicellular organism growth GO:0035264 161 0.013
negative regulation of protein modification process GO:0031400 163 0.013
carbohydrate homeostasis GO:0033500 128 0.013
neuronal action potential GO:0019228 54 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
response to purine containing compound GO:0014074 28 0.013
regulation of protein maturation GO:1903317 96 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
forebrain development GO:0030900 302 0.013
membrane organization GO:0061024 245 0.013
regulation of interleukin 10 secretion GO:2001179 4 0.013
regulation of kinase activity GO:0043549 249 0.013
dna dealkylation GO:0035510 11 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
negative regulation of protein processing GO:0010955 79 0.013
sulfur compound metabolic process GO:0006790 100 0.013
striated muscle tissue development GO:0014706 293 0.013
multi multicellular organism process GO:0044706 109 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
aromatic compound catabolic process GO:0019439 286 0.013
cation homeostasis GO:0055080 212 0.013
negative regulation of lymphocyte activation GO:0051250 91 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
lipid localization GO:0010876 126 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
locomotory behavior GO:0007626 195 0.012
sensory perception of light stimulus GO:0050953 54 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
metal ion homeostasis GO:0055065 189 0.012
positive regulation of phagocytosis GO:0050766 26 0.012
rhythmic process GO:0048511 174 0.012
diterpenoid metabolic process GO:0016101 24 0.012
negative regulation of cytokine production GO:0001818 84 0.012
lymphocyte differentiation GO:0030098 242 0.012
regulation of protein catabolic process GO:0042176 108 0.012
positive regulation of proteolysis GO:0045862 85 0.012
vesicle localization GO:0051648 86 0.012
nucleoside phosphate metabolic process GO:0006753 338 0.012
generation of precursor metabolites and energy GO:0006091 103 0.012
terpenoid metabolic process GO:0006721 25 0.012
leukocyte proliferation GO:0070661 172 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
myotube cell development GO:0014904 60 0.012
negative regulation of defense response GO:0031348 77 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
carbohydrate transport GO:0008643 62 0.012
cation transport GO:0006812 399 0.012
cellular response to external stimulus GO:0071496 88 0.012
hexose transport GO:0008645 56 0.012
regulation of leukocyte mediated immunity GO:0002703 104 0.012
male meiosis GO:0007140 37 0.012
tissue homeostasis GO:0001894 115 0.012
regulation of cell migration GO:0030334 219 0.012
blood circulation GO:0008015 195 0.012
vacuole organization GO:0007033 38 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.011
negative regulation of t cell activation GO:0050868 65 0.011
embryonic appendage morphogenesis GO:0035113 126 0.011
ribonucleotide biosynthetic process GO:0009260 59 0.011
blastocyst development GO:0001824 80 0.011
cell activation involved in immune response GO:0002263 126 0.011
retina homeostasis GO:0001895 23 0.011
cellular protein catabolic process GO:0044257 155 0.011
dendrite development GO:0016358 115 0.011
regulation of interleukin 1 alpha production GO:0032650 4 0.011
regulation of ossification GO:0030278 112 0.011
negative regulation of proteolysis GO:0045861 74 0.011
regulation of peptide transport GO:0090087 91 0.011
regulation of protein localization GO:0032880 231 0.011
lung development GO:0030324 164 0.011
glucose metabolic process GO:0006006 92 0.011
synaptic transmission GO:0007268 329 0.011
regulation of organelle organization GO:0033043 289 0.011
regulation of cell projection organization GO:0031344 206 0.011
regulation of vitamin metabolic process GO:0030656 3 0.011
dephosphorylation GO:0016311 129 0.011
nucleobase containing small molecule metabolic process GO:0055086 352 0.011
cellular response to inorganic substance GO:0071241 37 0.011
hindlimb morphogenesis GO:0035137 42 0.011
asymmetric stem cell division GO:0098722 3 0.011
regulation of t cell activation GO:0050863 170 0.011
negative regulation of kinase activity GO:0033673 81 0.011
bone development GO:0060348 120 0.011
cellular response to monosaccharide stimulus GO:0071326 47 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
cytosolic calcium ion homeostasis GO:0051480 70 0.011
synaptic vesicle localization GO:0097479 59 0.011
regulation of developmental pigmentation GO:0048070 14 0.011
sensory perception of chemical stimulus GO:0007606 51 0.010
lytic vacuole organization GO:0080171 21 0.010
regulation of protein transport GO:0051223 163 0.010
glucose transport GO:0015758 56 0.010
immune response regulating signaling pathway GO:0002764 125 0.010
sensory perception of sound GO:0007605 97 0.010
microtubule based movement GO:0007018 84 0.010
cellular response to hexose stimulus GO:0071331 47 0.010
skeletal muscle fiber development GO:0048741 58 0.010
hormone metabolic process GO:0042445 86 0.010
positive regulation of protein modification process GO:0031401 299 0.010
proteasomal protein catabolic process GO:0010498 98 0.010
positive regulation of map kinase activity GO:0043406 84 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
protein modification by small protein conjugation GO:0032446 187 0.010
regulation of interleukin 8 production GO:0032677 3 0.010
pallium development GO:0021543 120 0.010
negative regulation of transferase activity GO:0051348 85 0.010
modification dependent macromolecule catabolic process GO:0043632 133 0.010
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.010
regulation of hydrolase activity GO:0051336 246 0.010
positive regulation of leukocyte mediated immunity GO:0002705 70 0.010
regulation of muscle system process GO:0090257 80 0.010
establishment of vesicle localization GO:0051650 81 0.010
rho protein signal transduction GO:0007266 32 0.010

Guca1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.170
Human
disease of anatomical entity DOID:7 0 0.170
Human
eye and adnexa disease DOID:1492 0 0.170
Human
nervous system disease DOID:863 0 0.170
Human
retinal disease DOID:5679 0 0.101
Human
eye disease DOID:5614 0 0.101
Human
retinal degeneration DOID:8466 0 0.066
Human
retinitis pigmentosa DOID:10584 0 0.066
bone disease DOID:0080001 0 0.037
musculoskeletal system disease DOID:17 0 0.037
connective tissue disease DOID:65 0 0.037
disease of metabolism DOID:0014667 0 0.019
inherited metabolic disorder DOID:655 0 0.019
central nervous system disease DOID:331 0 0.014
neurodegenerative disease DOID:1289 0 0.010
disease of cellular proliferation DOID:14566 0 0.010