Mus musculus

69 known processes

H2-Aa

histocompatibility 2, class II antigen A, alpha

(Aliases: Aalpha,Ia1,I-Aalpha,IAalpha,H-2Aa,H2Aa,Ia-1)

H2-Aa biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 17 1.000
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 1.000
macrophage migration inhibitory factor signaling pathway GO:0035691 2 1.000
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 14 1.000
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 17 1.000
antigen processing and presentation of exogenous antigen GO:0019884 26 0.999
positive thymic t cell selection GO:0045059 13 0.999
Mouse
regulation of antigen processing and presentation GO:0002577 10 0.998
antigen processing and presentation of peptide antigen GO:0048002 29 0.996
antigen processing and presentation GO:0019882 47 0.996
b cell selection GO:0002339 3 0.988
cellular response to ammonium ion GO:0071242 2 0.982
adaptive immune response GO:0002250 155 0.975
Mouse
response to interferon gamma GO:0034341 34 0.959
cellular response to interferon gamma GO:0071346 25 0.954
chondroitin sulfate proteoglycan metabolic process GO:0050654 20 0.933
lymphocyte mediated immunity GO:0002449 139 0.926
Mouse
immunoglobulin mediated immune response GO:0016064 69 0.923
Mouse
b cell mediated immunity GO:0019724 71 0.913
Mouse
positive regulation of antigen processing and presentation GO:0002579 10 0.908
prostaglandin metabolic process GO:0006693 11 0.902
leukocyte differentiation GO:0002521 342 0.896
b cell differentiation GO:0030183 78 0.893
innate immune response GO:0045087 157 0.891
regulation of adaptive immune response GO:0002819 90 0.874
Mouse
positive t cell selection GO:0043368 23 0.869
Mouse
regulation of t cell activation GO:0050863 170 0.864
immune effector process GO:0002252 321 0.858
Mouse
cellular response to lipid GO:0071396 145 0.852
Rat
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.847
Mouse
positive regulation of cytokine production GO:0001819 174 0.845
lymphocyte differentiation GO:0030098 242 0.842
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.822
Mouse
humoral immune response GO:0006959 57 0.810
Mouse
t cell activation GO:0042110 289 0.802
leukocyte mediated immunity GO:0002443 174 0.761
Mouse
negative regulation of lymphocyte activation GO:0051250 91 0.757
Rat
regulation of cellular ketone metabolic process GO:0010565 66 0.747
positive regulation of type 2 immune response GO:0002830 9 0.741
positive regulation of t cell differentiation GO:0045582 52 0.737
cellular response to cytokine stimulus GO:0071345 189 0.733
myeloid leukocyte migration GO:0097529 57 0.731
germinal center formation GO:0002467 16 0.724
Mouse
positive regulation of response to cytokine stimulus GO:0060760 11 0.719
regulation of type 2 immune response GO:0002828 18 0.717
positive regulation of cell activation GO:0050867 158 0.713
regulation of lymphocyte activation GO:0051249 240 0.709
positive regulation of cellular amine metabolic process GO:0033240 5 0.708
cytokine production involved in immune response GO:0002367 34 0.693
proteoglycan metabolic process GO:0006029 38 0.692
production of molecular mediator of immune response GO:0002440 103 0.690
positive regulation of t cell activation GO:0050870 101 0.666
b cell activation GO:0042113 161 0.664
regulation of lymphocyte proliferation GO:0050670 117 0.657
Rat
macrophage cytokine production GO:0010934 9 0.651
t cell differentiation GO:0030217 174 0.644
fatty acid metabolic process GO:0006631 121 0.632
monocarboxylic acid metabolic process GO:0032787 191 0.613
b cell apoptotic process GO:0001783 19 0.607
positive regulation of germinal center formation GO:0002636 5 0.606
Mouse
mucopolysaccharide metabolic process GO:1903510 25 0.606
regulation of leukocyte proliferation GO:0070663 121 0.605
Rat
regulation of cell activation GO:0050865 289 0.600
leukocyte proliferation GO:0070661 172 0.579
Rat
positive regulation of neutrophil migration GO:1902624 12 0.576
cytokine production GO:0001816 319 0.571
negative thymic t cell selection GO:0045060 12 0.571
negative regulation of t cell activation GO:0050868 65 0.567
Rat
alpha beta t cell activation GO:0046631 91 0.553
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.541
Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.523
regulation of alpha beta t cell activation GO:0046634 53 0.519
positive regulation of macrophage cytokine production GO:0060907 7 0.513
chondroitin sulfate metabolic process GO:0030204 17 0.491
regulation of t helper 1 type immune response GO:0002825 17 0.488
regulation of dendritic cell antigen processing and presentation GO:0002604 7 0.485
negative regulation of peptide secretion GO:0002792 16 0.484
negative regulation of response to dna damage stimulus GO:2001021 10 0.482
sulfur compound metabolic process GO:0006790 100 0.477
negative regulation of dna damage response signal transduction by p53 class mediator GO:0043518 5 0.474
regulation of neutrophil chemotaxis GO:0090022 14 0.471
negative regulation of homeostatic process GO:0032845 71 0.470
cell chemotaxis GO:0060326 81 0.462
dendritic cell antigen processing and presentation GO:0002468 7 0.460
signal transduction by p53 class mediator GO:0072331 51 0.455
positive regulation of cell migration GO:0030335 109 0.451
positive regulation of chemotaxis GO:0050921 38 0.448
regulation of cellular amine metabolic process GO:0033238 20 0.448
regulation of lymphocyte differentiation GO:0045619 107 0.442
fatty acid biosynthetic process GO:0006633 41 0.441
myeloid cell differentiation GO:0030099 233 0.434
positive regulation of alpha beta t cell activation GO:0046635 39 0.434
granulocyte migration GO:0097530 43 0.430
activation of mapk activity GO:0000187 59 0.421
mapk cascade GO:0000165 281 0.413
negative regulation of b cell apoptotic process GO:0002903 7 0.402
unsaturated fatty acid metabolic process GO:0033559 31 0.400
unsaturated fatty acid biosynthetic process GO:0006636 15 0.394
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.393
lymphocyte proliferation GO:0046651 164 0.384
Rat
prostanoid metabolic process GO:0006692 11 0.382
neuron migration GO:0001764 122 0.375
amine metabolic process GO:0009308 45 0.369
positive regulation of lymphocyte activation GO:0051251 140 0.365
amide transport GO:0042886 138 0.359
regulation of mapk cascade GO:0043408 248 0.357
regulation of macrophage cytokine production GO:0010935 8 0.350
cellular ketone metabolic process GO:0042180 84 0.348
positive regulation of neutrophil chemotaxis GO:0090023 12 0.337
regulation of cytokine production involved in immune response GO:0002718 26 0.337
regulation of cytokine production GO:0001817 266 0.336
positive regulation of mapk cascade GO:0043410 170 0.335
negative regulation of cell activation GO:0050866 111 0.334
Rat
positive regulation of behavior GO:0048520 40 0.329
cellular amine metabolic process GO:0044106 44 0.328
central nervous system neuron differentiation GO:0021953 162 0.327
regulation of cellular amino acid metabolic process GO:0006521 5 0.327
positive regulation of kinase activity GO:0033674 155 0.322
negative regulation of apoptotic signaling pathway GO:2001234 104 0.318
fatty acid derivative biosynthetic process GO:1901570 15 0.317
positive regulation of lymphocyte differentiation GO:0045621 61 0.312
regulation of protein serine threonine kinase activity GO:0071900 157 0.310
reactive nitrogen species metabolic process GO:2001057 0 0.310
regulation of homeostatic process GO:0032844 182 0.310
aminoglycan metabolic process GO:0006022 34 0.309
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.307
regulation of protein kinase activity GO:0045859 232 0.305
extracellular matrix organization GO:0030198 147 0.302
positive regulation of adaptive immune response GO:0002821 61 0.301
Mouse
apoptotic signaling pathway GO:0097190 306 0.301
regulation of response to cytokine stimulus GO:0060759 23 0.295
cellular amino acid metabolic process GO:0006520 103 0.292
peptide cross linking via chondroitin 4 sulfate glycosaminoglycan GO:0019800 8 0.289
neutrophil migration GO:1990266 37 0.287
protein activation cascade GO:0072376 19 0.281
fatty acid derivative metabolic process GO:1901568 33 0.278
response to lipopolysaccharide GO:0032496 128 0.274
fibroblast proliferation GO:0048144 35 0.272
cellular response to dna damage stimulus GO:0006974 207 0.269
peptide transport GO:0015833 133 0.269
leukocyte homeostasis GO:0001776 79 0.267
negative regulation of gluconeogenesis GO:0045721 9 0.266
positive regulation of protein modification process GO:0031401 299 0.258
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.253
positive regulation of leukocyte differentiation GO:1902107 86 0.251
negative regulation of immune system process GO:0002683 209 0.250
Rat
regulation of t cell differentiation GO:0045580 83 0.244
nitrogen compound transport GO:0071705 271 0.243
cell adhesion GO:0007155 329 0.239
negative regulation of leukocyte differentiation GO:1902106 51 0.239
negative regulation of intracellular signal transduction GO:1902532 167 0.234
de novo protein folding GO:0006458 9 0.227
Mouse
positive regulation of cytokine production involved in immune response GO:0002720 19 0.224
positive regulation of b cell proliferation GO:0030890 24 0.221
negative regulation of cell proliferation GO:0008285 296 0.220
Rat
regulation of b cell apoptotic process GO:0002902 13 0.219
positive regulation of protein phosphorylation GO:0001934 242 0.215
positive regulation of leukocyte proliferation GO:0070665 73 0.214
positive regulation of dendritic cell antigen processing and presentation GO:0002606 7 0.213
regulation of t cell mediated immunity GO:0002709 34 0.213
b cell homeostasis GO:0001782 34 0.212
protein folding GO:0006457 28 0.209
Mouse
myeloid leukocyte cytokine production GO:0061082 12 0.203
regulation of mature b cell apoptotic process GO:0002905 4 0.198
thymic t cell selection GO:0045061 22 0.197
Mouse
glycosaminoglycan metabolic process GO:0030203 34 0.195
regulation of apoptotic signaling pathway GO:2001233 197 0.195
b cell proliferation GO:0042100 53 0.195
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.195
regulation of peptide transport GO:0090087 91 0.194
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.194
cytokine mediated signaling pathway GO:0019221 115 0.191
interleukin 12 secretion GO:0072610 3 0.190
metanephric glomerular visceral epithelial cell development GO:0072249 2 0.190
cellular response to glucocorticoid stimulus GO:0071385 13 0.187
Rat
homeostasis of number of cells GO:0048872 210 0.186
regulation of gluconeogenesis GO:0006111 30 0.183
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.183
t helper 1 type immune response GO:0042088 25 0.181
icosanoid metabolic process GO:0006690 33 0.177
cellular lipid metabolic process GO:0044255 323 0.176
regulation of erk1 and erk2 cascade GO:0070372 71 0.175
negative regulation of macrophage apoptotic process GO:2000110 3 0.175
cell migration involved in metanephros development GO:0035788 2 0.175
humoral immune response mediated by circulating immunoglobulin GO:0002455 14 0.170
regulation of monocyte chemotaxis GO:0090025 3 0.166
regulation of kinase activity GO:0043549 249 0.166
t cell proliferation GO:0042098 120 0.165
Rat
positive regulation of transferase activity GO:0051347 167 0.163
regulation of leukocyte differentiation GO:1902105 159 0.161
peptidyl tyrosine phosphorylation GO:0018108 143 0.158
positive regulation of map kinase activity GO:0043406 84 0.158
positive regulation of eosinophil migration GO:2000418 2 0.157
immunoglobulin production GO:0002377 73 0.155
cellular response to organonitrogen compound GO:0071417 145 0.153
carboxylic acid biosynthetic process GO:0046394 86 0.149
calcium ion transport into cytosol GO:0060402 48 0.148
response to symbiont GO:0009608 2 0.147
response to monosaccharide GO:0034284 67 0.146
positive regulation of fibroblast proliferation GO:0048146 20 0.141
positive regulation of protein kinase activity GO:0045860 144 0.137
regulation of intrinsic apoptotic signaling pathway in response to dna damage GO:1902229 14 0.137
lymphocyte homeostasis GO:0002260 64 0.136
intracellular protein transport GO:0006886 204 0.136
peptide cross linking GO:0018149 10 0.135
regulation of response to dna damage stimulus GO:2001020 34 0.132
positive regulation of chemokine production GO:0032722 22 0.123
fat cell differentiation GO:0045444 160 0.122
positive regulation of metanephric glomerulus development GO:0072300 4 0.120
regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902253 13 0.119
chemotaxis GO:0006935 247 0.117
chemokine production GO:0032602 34 0.117
monocarboxylic acid biosynthetic process GO:0072330 61 0.116
regulation of germinal center formation GO:0002634 10 0.113
Mouse
positive regulation of t helper 1 type immune response GO:0002827 12 0.112
regulation of production of molecular mediator of immune response GO:0002700 65 0.112
negative regulation of defense response GO:0031348 77 0.110
glucose homeostasis GO:0042593 128 0.109
small gtpase mediated signal transduction GO:0007264 97 0.108
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.107
regulation of b cell activation GO:0050864 81 0.107
leukocyte apoptotic process GO:0071887 71 0.107
metanephric glomerular epithelial cell development GO:0072313 2 0.106
regulation of map kinase activity GO:0043405 120 0.103
cell substrate adhesion GO:0031589 130 0.102
negative regulation of mature b cell apoptotic process GO:0002906 4 0.101
maintenance of location GO:0051235 89 0.100
regulation of striated muscle cell differentiation GO:0051153 81 0.100
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway GO:0002484 3 0.099
metal ion homeostasis GO:0055065 189 0.099
regulation of intracellular transport GO:0032386 159 0.097
positive regulation of cell adhesion GO:0045785 80 0.096
natural killer cell chemotaxis GO:0035747 1 0.094
prostanoid biosynthetic process GO:0046457 8 0.094
response to ammonium ion GO:0060359 21 0.093
negative regulation of protein metabolic process GO:0051248 282 0.093
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.092
positive regulation of myeloid leukocyte cytokine production involved in immune response GO:0061081 9 0.091
positive regulation of immune effector process GO:0002699 107 0.091
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.091
positive regulation of epithelial cell differentiation involved in kidney development GO:2000698 2 0.089
glycoprotein metabolic process GO:0009100 116 0.089
iron ion import GO:0097286 5 0.089
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.088
regulation of fibroblast proliferation GO:0048145 34 0.087
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.085
negative regulation of t cell proliferation GO:0042130 38 0.085
Rat
cellular metal ion homeostasis GO:0006875 151 0.084
organic acid biosynthetic process GO:0016053 86 0.084
cellular protein complex assembly GO:0043623 116 0.083
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 24 0.082
response to organic cyclic compound GO:0014070 198 0.082
Rat
cation transport GO:0006812 399 0.081
type 2 immune response GO:0042092 23 0.081
activation of immune response GO:0002253 138 0.079
peptidyl amino acid modification GO:0018193 336 0.079
muscle tissue development GO:0060537 308 0.079
hexose biosynthetic process GO:0019319 39 0.078
response to isoquinoline alkaloid GO:0014072 9 0.077
positive regulation of b cell chemotaxis GO:2000538 2 0.076
antigen processing and presentation of endogenous peptide antigen via mhc class ib GO:0002476 4 0.075
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.074
regulation of secretion GO:0051046 274 0.074
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.073
regulation of reactive oxygen species metabolic process GO:2000377 40 0.073
regulation of rho protein signal transduction GO:0035023 71 0.072
cellular response to steroid hormone stimulus GO:0071383 33 0.072
Rat
response to morphine GO:0043278 9 0.071
peptidyl tyrosine modification GO:0018212 145 0.071
cell killing GO:0001906 67 0.070
antigen processing and presentation via mhc class ib GO:0002475 8 0.069
regulation of response to biotic stimulus GO:0002831 38 0.069
glomerular visceral epithelial cell development GO:0072015 6 0.069
cellular calcium ion homeostasis GO:0006874 119 0.068
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.068
erk1 and erk2 cascade GO:0070371 77 0.068
muscle cell development GO:0055001 133 0.067
cellular chemical homeostasis GO:0055082 215 0.067
positive regulation of cd4 positive alpha beta t cell proliferation GO:2000563 1 0.067
leukocyte migration GO:0050900 124 0.067
kidney development GO:0001822 213 0.066
regulation of leukocyte mediated immunity GO:0002703 104 0.065
regulation of protein secretion GO:0050708 82 0.064
alpha beta t cell proliferation GO:0046633 21 0.063
ribose phosphate metabolic process GO:0019693 291 0.063
negative regulation of t cell differentiation GO:0045581 23 0.062
regulation of chemokine c x c motif ligand 2 production GO:2000341 3 0.061
prostaglandin biosynthetic process GO:0001516 8 0.061
response to dexamethasone GO:0071548 8 0.061
cellular homeostasis GO:0019725 240 0.061
regulation of defense response GO:0031347 233 0.060
regulation of platelet derived growth factor receptor alpha signaling pathway GO:2000583 2 0.060
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.060
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.060
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.059
granulocyte chemotaxis GO:0071621 39 0.059
positive regulation of apoptotic process GO:0043065 217 0.058
positive regulation of cell substrate adhesion GO:0010811 47 0.058
regulation of cell adhesion GO:0030155 154 0.057
regulation of cell motility GO:2000145 236 0.057
positive regulation of protein kinase b signaling GO:0051897 32 0.057
renal system development GO:0072001 225 0.057
positive regulation of t cell mediated immunity GO:0002711 24 0.056
organic acid catabolic process GO:0016054 51 0.056
cellular response to extracellular stimulus GO:0031668 81 0.056
lymphocyte apoptotic process GO:0070227 54 0.056
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.055
muscle cell differentiation GO:0042692 261 0.055
icosanoid biosynthetic process GO:0046456 15 0.055
cellular response to alcohol GO:0097306 23 0.054
regulation of hormone levels GO:0010817 211 0.054
hormone secretion GO:0046879 128 0.053
regulation of b cell chemotaxis GO:2000537 2 0.052
regulation of chemotaxis GO:0050920 53 0.052
negative regulation of secretion GO:0051048 61 0.051
ear development GO:0043583 200 0.051
Mouse
interleukin 1 beta production GO:0032611 30 0.051
myeloid leukocyte differentiation GO:0002573 119 0.049
regulation of peptide secretion GO:0002791 77 0.048
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.048
positive regulation of chemokine c x c motif ligand 2 production GO:2000343 3 0.047
branching morphogenesis of an epithelial tube GO:0048754 159 0.047
male sex differentiation GO:0046661 109 0.047
cellular response to ketone GO:1901655 12 0.047
negative regulation of synapse assembly GO:0051964 3 0.047
inflammatory response GO:0006954 244 0.046
oxidation reduction process GO:0055114 342 0.046
synapse organization GO:0050808 125 0.046
carbohydrate homeostasis GO:0033500 128 0.046
rho protein signal transduction GO:0007266 32 0.045
regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:1902165 8 0.045
cellular macromolecule catabolic process GO:0044265 206 0.045
heterocycle catabolic process GO:0046700 280 0.045
lipid modification GO:0030258 65 0.043
striated muscle tissue development GO:0014706 293 0.042
regulation of t cell proliferation GO:0042129 92 0.042
Rat
lipid biosynthetic process GO:0008610 179 0.042
regulation of epithelial cell differentiation involved in kidney development GO:2000696 10 0.042
cellular component assembly involved in morphogenesis GO:0010927 139 0.041
peptide secretion GO:0002790 114 0.041
regulation of cellular component biogenesis GO:0044087 181 0.041
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 3 0.041
positive regulation of secretion GO:0051047 130 0.041
response to extracellular stimulus GO:0009991 127 0.040
hormone metabolic process GO:0042445 86 0.040
regulation of ion transport GO:0043269 215 0.039
angiogenesis GO:0001525 201 0.039
fatty acid beta oxidation GO:0006635 16 0.039
small molecule biosynthetic process GO:0044283 132 0.039
purine nucleoside metabolic process GO:0042278 241 0.039
regulation of cytoplasmic transport GO:1903649 112 0.039
nucleoside triphosphate catabolic process GO:0009143 205 0.039
cellular divalent inorganic cation homeostasis GO:0072503 127 0.038
regulation of transferase activity GO:0051338 263 0.038
purine nucleoside catabolic process GO:0006152 205 0.038
multicellular organismal homeostasis GO:0048871 164 0.038
cellular response to molecule of bacterial origin GO:0071219 83 0.038
negative regulation of fat cell differentiation GO:0045599 36 0.038
monocarboxylic acid catabolic process GO:0072329 27 0.038
regulation of establishment of protein localization GO:0070201 181 0.038
positive regulation of cytokine secretion GO:0050715 41 0.037
cellular response to external stimulus GO:0071496 88 0.036
positive regulation of thymocyte migration GO:2000412 2 0.036
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.035
negative regulation of protein modification process GO:0031400 163 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.035
cell junction maintenance GO:0034331 4 0.035
negative regulation of phosphorylation GO:0042326 166 0.035
ras protein signal transduction GO:0007265 77 0.035
purine ribonucleotide metabolic process GO:0009150 290 0.035
purine nucleoside triphosphate metabolic process GO:0009144 226 0.035
histone modification GO:0016570 159 0.034
leukocyte chemotaxis GO:0030595 69 0.034
regulation of endocytosis GO:0030100 69 0.034
cerebellar cortex morphogenesis GO:0021696 32 0.034
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.034
protein catabolic process GO:0030163 221 0.033
regulation of cell migration GO:0030334 219 0.033
regulation of protein localization to nucleus GO:1900180 60 0.033
male gamete generation GO:0048232 285 0.033
positive regulation of endocytosis GO:0045807 42 0.033
response to transforming growth factor beta GO:0071559 88 0.033
cellular response to lipopolysaccharide GO:0071222 77 0.033
positive regulation of b cell activation GO:0050871 49 0.032
protein heterooligomerization GO:0051291 14 0.032
gland development GO:0048732 330 0.032
immunoglobulin production in mucosal tissue GO:0002426 3 0.032
blood vessel morphogenesis GO:0048514 285 0.032
carboxylic acid catabolic process GO:0046395 51 0.031
reactive oxygen species biosynthetic process GO:1903409 8 0.031
actin cytoskeleton organization GO:0030036 220 0.031
membrane lipid metabolic process GO:0006643 53 0.031
renal system process GO:0003014 48 0.031
regulation of myotube differentiation GO:0010830 62 0.031
positive regulation of renal albumin absorption GO:2000534 1 0.030
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.030
regulation of myeloid cell differentiation GO:0045637 96 0.030
tissue homeostasis GO:0001894 115 0.030
organ or tissue specific immune response GO:0002251 13 0.030
carbohydrate biosynthetic process GO:0016051 74 0.030
metanephric glomerular visceral epithelial cell differentiation GO:0072248 2 0.029
metanephric glomerular epithelium development GO:0072244 3 0.029
developmental growth involved in morphogenesis GO:0060560 138 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.029
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.029
regulation of intracellular protein transport GO:0033157 82 0.029
antigen processing and presentation of exogenous peptide antigen via mhc class i GO:0042590 6 0.029
fatty acid oxidation GO:0019395 28 0.029
protein kinase b signaling GO:0043491 74 0.029
negative regulation of protein phosphorylation GO:0001933 126 0.028
t cell migration GO:0072678 19 0.028
negative regulation of phosphorus metabolic process GO:0010563 184 0.028
metanephric nephron development GO:0072210 34 0.028
g protein coupled receptor signaling pathway GO:0007186 243 0.028
skeletal muscle organ development GO:0060538 163 0.028
organic cyclic compound catabolic process GO:1901361 295 0.028
regulation of cell substrate adhesion GO:0010810 73 0.027
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.027
antigen processing and presentation of peptide antigen via mhc class ib GO:0002428 5 0.027
regulation of cell killing GO:0031341 40 0.027
positive regulation of protein tyrosine kinase activity GO:0061098 10 0.027
ribonucleoside catabolic process GO:0042454 206 0.027
cellular response to thyroid hormone stimulus GO:0097067 1 0.027
endocytosis GO:0006897 168 0.027
spermatogenesis GO:0007283 284 0.027
regulation of dendritic cell dendrite assembly GO:2000547 2 0.027
cellular protein catabolic process GO:0044257 155 0.026
t cell mediated cytotoxicity GO:0001913 26 0.026
striated muscle cell development GO:0055002 125 0.026
regulation of lipid metabolic process GO:0019216 118 0.026
cellular response to hormone stimulus GO:0032870 150 0.026
Rat
positive regulation of glucose import GO:0046326 14 0.026
response to ketone GO:1901654 15 0.025
sequestering of calcium ion GO:0051208 18 0.025
leukocyte mediated cytotoxicity GO:0001909 62 0.025
cellular response to insulin stimulus GO:0032869 78 0.025
brown fat cell differentiation GO:0050873 36 0.025
positive regulation of nervous system development GO:0051962 221 0.025
positive regulation of secretion by cell GO:1903532 114 0.025
regulation of ras protein signal transduction GO:0046578 114 0.025
regulation of carbohydrate biosynthetic process GO:0043255 40 0.025
t cell selection GO:0045058 34 0.025
Mouse
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.025
positive regulation of camp dependent protein kinase activity GO:2000481 3 0.024
cytokine biosynthetic process GO:0042089 68 0.024
positive regulation of rho gtpase activity GO:0032321 41 0.024
response to steroid hormone GO:0048545 56 0.024
Rat
divalent inorganic cation homeostasis GO:0072507 138 0.024
peptide hormone secretion GO:0030072 109 0.024
chemokine c x c motif ligand 2 production GO:0072567 3 0.023
protein acylation GO:0043543 64 0.023
regulation of epithelial cell proliferation GO:0050678 141 0.023
regulation of gtp catabolic process GO:0033124 113 0.023
dendritic cell dendrite assembly GO:0097026 2 0.023
cellular response to growth factor stimulus GO:0071363 197 0.023
macromolecule catabolic process GO:0009057 281 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.023
immune response regulating signaling pathway GO:0002764 125 0.023
organonitrogen compound catabolic process GO:1901565 264 0.022
mucosal immune response GO:0002385 13 0.022
regulation of renal albumin absorption GO:2000532 1 0.022
negative regulation of lymphocyte proliferation GO:0050672 45 0.022
Rat
regulation of cell cycle GO:0051726 281 0.022
antigen processing and presentation of exogenous peptide antigen via mhc class ib GO:0002477 3 0.022
cardiocyte differentiation GO:0035051 87 0.022
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 9 0.022
microglia development GO:0014005 2 0.022
osteoclast differentiation GO:0030316 62 0.022
lipid oxidation GO:0034440 29 0.022
cdc42 protein signal transduction GO:0032488 0 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
positive regulation of cellular catabolic process GO:0031331 148 0.022
regulation of nucleoside metabolic process GO:0009118 130 0.022
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.022
protein ubiquitination GO:0016567 171 0.022
response to alkaloid GO:0043279 34 0.022
regulation of protein localization GO:0032880 231 0.021
regulation of nucleotide catabolic process GO:0030811 122 0.021
positive regulation of leukocyte mediated immunity GO:0002705 70 0.021
natural killer cell mediated cytotoxicity GO:0042267 29 0.021
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.021
nucleotide catabolic process GO:0009166 217 0.021
anatomical structure homeostasis GO:0060249 145 0.021
positive regulation of cell development GO:0010720 237 0.021
epithelial cell proliferation GO:0050673 174 0.021
regulation of muscle tissue development GO:1901861 97 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
cellular glucose homeostasis GO:0001678 52 0.020
cell cell adhesion GO:0098609 41 0.020
glycerolipid metabolic process GO:0046486 122 0.020
cellular response to biotic stimulus GO:0071216 92 0.020
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.020

H2-Aa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.350
disease of anatomical entity DOID:7 0 0.350
nervous system disease DOID:863 0 0.350
immune system disease DOID:2914 0 0.286
hypersensitivity reaction disease DOID:0060056 0 0.286
hypersensitivity reaction type ii disease DOID:417 0 0.065
neurodegenerative disease DOID:1289 0 0.057