|
|
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii
|
GO:0002504 |
17 |
0.999
|
|
|
|
antigen processing and presentation of exogenous peptide antigen
|
GO:0002478 |
21 |
0.999
|
|
|
|
macrophage migration inhibitory factor signaling pathway
|
GO:0035691 |
2 |
0.998
|
|
|
|
antigen processing and presentation of exogenous peptide antigen via mhc class ii
|
GO:0019886 |
14 |
0.995
|
|
|
|
antigen processing and presentation of exogenous antigen
|
GO:0019884 |
26 |
0.995
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.993
|
|
|
|
de novo protein folding
|
GO:0006458 |
9 |
0.987
|
|
|
|
antigen processing and presentation of peptide antigen
|
GO:0048002 |
29 |
0.986
|
|
|
|
antigen processing and presentation of peptide antigen via mhc class ii
|
GO:0002495 |
17 |
0.984
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.976
|
Mouse |
|
|
positive thymic t cell selection
|
GO:0045059 |
13 |
0.950
|
|
|
|
positive regulation of germinal center formation
|
GO:0002636 |
5 |
0.933
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.923
|
Mouse |
|
|
innate immune response
|
GO:0045087 |
157 |
0.923
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.891
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.890
|
Mouse |
|
|
regulation of antigen processing and presentation
|
GO:0002577 |
10 |
0.873
|
Mouse |
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.841
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.806
|
Mouse |
|
|
regulation of germinal center formation
|
GO:0002634 |
10 |
0.785
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
25 |
0.781
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.779
|
Mouse |
|
|
germinal center formation
|
GO:0002467 |
16 |
0.758
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.755
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.737
|
Mouse |
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.725
|
Mouse |
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.716
|
Mouse |
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.662
|
Mouse |
|
|
t cell selection
|
GO:0045058 |
34 |
0.653
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.652
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.644
|
|
|
|
prostaglandin metabolic process
|
GO:0006693 |
11 |
0.639
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.615
|
Mouse |
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.610
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.610
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.592
|
Mouse |
|
|
humoral immune response
|
GO:0006959 |
57 |
0.569
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.558
|
Mouse |
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.557
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.539
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.526
|
Mouse |
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.519
|
Mouse |
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.518
|
|
|
|
positive regulation of type 2 immune response
|
GO:0002830 |
9 |
0.504
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.504
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.503
|
Mouse |
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.501
|
|
|
|
positive regulation of antigen processing and presentation
|
GO:0002579 |
10 |
0.494
|
Mouse |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.494
|
Mouse |
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.478
|
|
|
|
icosanoid biosynthetic process
|
GO:0046456 |
15 |
0.474
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.448
|
Mouse |
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.441
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.435
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.434
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.421
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.416
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.416
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.414
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.413
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.413
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.394
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.392
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.391
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.386
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.381
|
|
|
|
dendritic cell antigen processing and presentation
|
GO:0002468 |
7 |
0.376
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.373
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.369
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.368
|
Mouse |
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.362
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.361
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.352
|
Mouse |
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.344
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.340
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
61 |
0.337
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.336
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.328
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.324
|
|
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.318
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.312
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.310
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.305
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.298
|
Mouse |
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.297
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.291
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.287
|
Mouse |
|
|
regulation of dendritic cell antigen processing and presentation
|
GO:0002604 |
7 |
0.286
|
|
|
|
proteoglycan metabolic process
|
GO:0006029 |
38 |
0.286
|
|
|
|
chaperone mediated protein folding
|
GO:0061077 |
10 |
0.279
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.277
|
|
|
|
negative regulation of b cell apoptotic process
|
GO:0002903 |
7 |
0.272
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.271
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.266
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.265
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.264
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.264
|
|
|
|
positive regulation of macrophage cytokine production
|
GO:0060907 |
7 |
0.263
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.262
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
13 |
0.262
|
|
|
|
negative regulation of peptide secretion
|
GO:0002792 |
16 |
0.259
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.253
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.246
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.239
|
|
|
|
regulation of b cell apoptotic process
|
GO:0002902 |
13 |
0.239
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.239
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.236
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.235
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.233
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.230
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.226
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.224
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.222
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.219
|
Mouse |
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.219
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.218
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.217
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.216
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.206
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.205
|
Mouse |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.204
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.204
|
Mouse |
|
|
chondroitin sulfate metabolic process
|
GO:0030204 |
17 |
0.204
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.202
|
|
|
|
unsaturated fatty acid biosynthetic process
|
GO:0006636 |
15 |
0.200
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.198
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.195
|
|
|
|
negative regulation of lymphocyte apoptotic process
|
GO:0070229 |
24 |
0.194
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
34 |
0.193
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.191
|
|
|
|
fatty acid derivative biosynthetic process
|
GO:1901570 |
15 |
0.191
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.181
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.177
|
|
|
|
protein folding
|
GO:0006457 |
28 |
0.172
|
|
|
|
positive regulation of smooth muscle cell migration
|
GO:0014911 |
4 |
0.171
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.168
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.167
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.166
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.166
|
Mouse |
|
|
unsaturated fatty acid metabolic process
|
GO:0033559 |
31 |
0.165
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.164
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.163
|
|
|
|
chemokine c x c motif ligand 2 production
|
GO:0072567 |
3 |
0.162
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.160
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.160
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.158
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.155
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
17 |
0.153
|
|
|
|
prostaglandin biosynthetic process
|
GO:0001516 |
8 |
0.149
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.148
|
|
|
|
prostanoid biosynthetic process
|
GO:0046457 |
8 |
0.147
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.146
|
|
|
|
positive regulation of eosinophil migration
|
GO:2000418 |
2 |
0.145
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.144
|
|
|
|
aminoglycan metabolic process
|
GO:0006022 |
34 |
0.143
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.140
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.139
|
|
|
|
regulation of macrophage cytokine production
|
GO:0010935 |
8 |
0.138
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.137
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.134
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.129
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.128
|
|
|
|
positive regulation of dendritic cell antigen processing and presentation
|
GO:0002606 |
7 |
0.122
|
|
|
|
positive regulation of chemokine c x c motif ligand 2 production
|
GO:2000343 |
3 |
0.120
|
|
|
|
chondroitin sulfate proteoglycan metabolic process
|
GO:0050654 |
20 |
0.120
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.119
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.119
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.118
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.118
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
11 |
0.117
|
|
|
|
fatty acid derivative metabolic process
|
GO:1901568 |
33 |
0.116
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.115
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.114
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.114
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.110
|
|
|
|
natural killer cell chemotaxis
|
GO:0035747 |
1 |
0.110
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
35 |
0.110
|
|
|
|
regulation of natural killer cell mediated immunity
|
GO:0002715 |
19 |
0.109
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.109
|
|
|
|
peptide cross linking via chondroitin 4 sulfate glycosaminoglycan
|
GO:0019800 |
8 |
0.108
|
|
|
|
response to isoquinoline alkaloid
|
GO:0014072 |
9 |
0.106
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.104
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.104
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.103
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.102
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.101
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.099
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.098
|
|
|
|
negative regulation of regulatory t cell differentiation
|
GO:0045590 |
2 |
0.098
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.097
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.095
|
|
|
|
positive regulation of cytokine production involved in immune response
|
GO:0002720 |
19 |
0.095
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.094
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.094
|
|
|
|
regulation of natural killer cell chemotaxis
|
GO:2000501 |
1 |
0.094
|
|
|
|
iron ion import into cell
|
GO:0097459 |
4 |
0.093
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.093
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.092
|
|
|
|
regulation of intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:1902253 |
13 |
0.092
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.091
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.089
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.088
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.088
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.086
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.085
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.085
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.085
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.083
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
33 |
0.082
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.082
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.082
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.082
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.082
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.081
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.080
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.080
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.080
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
19 |
0.080
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.080
|
|
|
|
icosanoid metabolic process
|
GO:0006690 |
33 |
0.079
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.079
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.078
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.078
|
|
|
|
myeloid leukocyte cytokine production
|
GO:0061082 |
12 |
0.077
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.077
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.077
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.077
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.076
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.076
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.076
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.076
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.075
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.075
|
|
|
|
negative regulation of gluconeogenesis
|
GO:0045721 |
9 |
0.074
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.074
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.074
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.073
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.073
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.073
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.072
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.071
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.071
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.070
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.070
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.070
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.070
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.070
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.069
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.069
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
23 |
0.069
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.068
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.068
|
|
|
|
protein activation cascade
|
GO:0072376 |
19 |
0.067
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.066
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.065
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.065
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.064
|
|
|
|
positive regulation of cd4 positive alpha beta t cell proliferation
|
GO:2000563 |
1 |
0.064
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.064
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.064
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.063
|
|
|
|
response to corticosteroid
|
GO:0031960 |
20 |
0.063
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.063
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.063
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.062
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.062
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.062
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.062
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.061
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.061
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.061
|
|
|
|
antigen processing and presentation of endogenous peptide antigen via mhc class ib
|
GO:0002476 |
4 |
0.060
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.059
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.059
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
34 |
0.059
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.059
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.058
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.058
|
|
|
|
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway
|
GO:0002484 |
3 |
0.058
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.058
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.058
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.058
|
|
|
|
regulation of myd88 independent toll like receptor signaling pathway
|
GO:0034127 |
1 |
0.058
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.056
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.056
|
|
|
|
t cell mediated cytotoxicity
|
GO:0001913 |
26 |
0.056
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.056
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.055
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.055
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.055
|
|
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.054
|
|
|
|
cell migration involved in metanephros development
|
GO:0035788 |
2 |
0.054
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.054
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.054
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.054
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.054
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.053
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.053
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.052
|
|
|
|
positive regulation of t helper 2 cell cytokine production
|
GO:2000553 |
3 |
0.052
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
20 |
0.051
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
34 |
0.051
|
|
|
|
regulation of intrinsic apoptotic signaling pathway in response to dna damage
|
GO:1902229 |
14 |
0.050
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.050
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.050
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.049
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.049
|
|
|
|
positive regulation of natural killer cell chemotaxis
|
GO:2000503 |
1 |
0.048
|
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
25 |
0.047
|
|
|
|
cellular response to drug
|
GO:0035690 |
15 |
0.047
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.047
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.047
|
|
|
|
cd8 positive alpha beta t cell proliferation
|
GO:0035740 |
1 |
0.046
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.046
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.046
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.046
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.046
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.045
|
|
|
|
response to morphine
|
GO:0043278 |
9 |
0.044
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.044
|
|
|
|
negative regulation of mature b cell apoptotic process
|
GO:0002906 |
4 |
0.043
|
|
|
|
positive regulation of myeloid leukocyte cytokine production involved in immune response
|
GO:0061081 |
9 |
0.043
|
|
|
|
peptide cross linking
|
GO:0018149 |
10 |
0.043
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.043
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.043
|
|
|
|
cellular response to ammonium ion
|
GO:0071242 |
2 |
0.042
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.042
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.042
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.041
|
|
|
|
b cell selection
|
GO:0002339 |
3 |
0.041
|
Mouse |
|
|
regulation of b cell chemotaxis
|
GO:2000537 |
2 |
0.041
|
|
|
|
humoral immune response mediated by circulating immunoglobulin
|
GO:0002455 |
14 |
0.041
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.041
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.041
|
|
|
|
positive regulation of immunoglobulin production in mucosal tissue
|
GO:2000558 |
1 |
0.041
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.041
|
Mouse |
|
|
positive regulation of natural killer cell mediated cytotoxicity
|
GO:0045954 |
16 |
0.040
|
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.040
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.040
|
|
|
|
macrophage cytokine production
|
GO:0010934 |
9 |
0.040
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.039
|
|
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
19 |
0.039
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.039
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.039
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.038
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.038
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.038
|
|
|
|
b cell apoptotic process
|
GO:0001783 |
19 |
0.038
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.037
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
47 |
0.037
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.037
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.037
|
|
|
|
regulation of dendritic cell dendrite assembly
|
GO:2000547 |
2 |
0.037
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.037
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.036
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.035
|
|
|
|
negative regulation of dna damage response signal transduction by p53 class mediator
|
GO:0043518 |
5 |
0.035
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.035
|
|
|
|
positive regulation of metanephric glomerulus development
|
GO:0072300 |
4 |
0.035
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.034
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.034
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.034
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.033
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.033
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.033
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.033
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.033
|
|
|
|
metanephric mesenchymal cell migration
|
GO:0035789 |
2 |
0.033
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.033
|
|
|
|
positive regulation of response to cytokine stimulus
|
GO:0060760 |
11 |
0.032
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.032
|
Mouse |
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.032
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.032
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.032
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.032
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.031
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.031
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.031
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.031
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.031
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.031
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.030
|
Mouse |
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.030
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.030
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.030
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.029
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.029
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.029
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.029
|
|
|
|
regulation of chemokine c x c motif ligand 2 production
|
GO:2000341 |
3 |
0.029
|
|
|
|
metanephric glomerular epithelium development
|
GO:0072244 |
3 |
0.029
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.029
|
|
|
|
regulation of cd8 positive alpha beta t cell proliferation
|
GO:2000564 |
1 |
0.029
|
|
|
|
eosinophil migration
|
GO:0072677 |
3 |
0.029
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.029
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.029
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.029
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.029
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.029
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.028
|
|
|
|
positive regulation of t cell mediated immunity
|
GO:0002711 |
24 |
0.028
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.028
|
|
|
|
antigen processing and presentation of endogenous peptide antigen via mhc class i
|
GO:0019885 |
3 |
0.028
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.028
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.027
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.027
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.027
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.027
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.027
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.027
|
|
|
|
glycosaminoglycan metabolic process
|
GO:0030203 |
34 |
0.026
|
|
|
|
purinergic nucleotide receptor signaling pathway
|
GO:0035590 |
3 |
0.026
|
|
|
|
positive regulation of thymocyte migration
|
GO:2000412 |
2 |
0.026
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.026
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.026
|
|
|
|
cd4 positive alpha beta t cell proliferation
|
GO:0035739 |
2 |
0.026
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.026
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.026
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.026
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.026
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.026
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.026
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.026
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.025
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.025
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.025
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.025
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.025
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.025
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.025
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.025
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.025
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.025
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.025
|
|
|
|
cell cell adhesion
|
GO:0098609 |
41 |
0.024
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.024
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.024
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.024
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.024
|
|
|
|
immunoglobulin production in mucosal tissue
|
GO:0002426 |
3 |
0.023
|
|
|
|
cellular response to thyroid hormone stimulus
|
GO:0097067 |
1 |
0.023
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
31 |
0.023
|
|
|
|
iron ion homeostasis
|
GO:0055072 |
36 |
0.023
|
|
|
|
regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:1902165 |
8 |
0.023
|
|
|
|
positive regulation of type i interferon mediated signaling pathway
|
GO:0060340 |
4 |
0.023
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
36 |
0.023
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.023
|
|
|
|
hexose biosynthetic process
|
GO:0019319 |
39 |
0.023
|
|
|
|
astrocyte cell migration
|
GO:0043615 |
3 |
0.022
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.022
|
|
|
|
negative regulation of granulocyte differentiation
|
GO:0030853 |
3 |
0.022
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.022
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.022
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.022
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.022
|
|
|
|
cellular response to corticosteroid stimulus
|
GO:0071384 |
13 |
0.022
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.022
|
|
|
|
regulation of angiotensin levels in blood
|
GO:0002002 |
4 |
0.022
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.022
|
|
|
|
thymocyte migration
|
GO:0072679 |
2 |
0.021
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.021
|
|
|
|
microglia development
|
GO:0014005 |
2 |
0.021
|
|
|
|
regulation of cdc42 protein signal transduction
|
GO:0032489 |
5 |
0.021
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.021
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.021
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.021
|
|
|
|
regulation of mature b cell apoptotic process
|
GO:0002905 |
4 |
0.021
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.021
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.021
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.020
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.020
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.020
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.020
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.020
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.020
|
|
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.020
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.020
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.020
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.020
|
|
|
|
response to symbiont
|
GO:0009608 |
2 |
0.020
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.020
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.019
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.019
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.019
|
|
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.019
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.019
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.019
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.019
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.019
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.019
|
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.019
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.019
|
|
