Mus musculus

0 known processes

H2-Q7

histocompatibility 2, Q region locus 7

(Aliases: Qa7,Qa-2,Q9,Qa-7,H-2Q7,Ped)

H2-Q7 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of t cell mediated cytotoxicity GO:0001916 15 1.000
regulation of tolerance induction dependent upon immune response GO:0002652 1 1.000
negative regulation of natural killer cell mediated immunity GO:0002716 5 0.998
regulation of t cell mediated cytotoxicity GO:0001914 18 0.997
antigen processing and presentation via mhc class ib GO:0002475 8 0.996
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.986
iron ion import into cell GO:0097459 4 0.983
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway GO:0002484 3 0.983
antigen processing and presentation of endogenous peptide antigen via mhc class ib GO:0002476 4 0.981
t cell mediated immunity GO:0002456 50 0.943
regulation of natural killer cell mediated immunity GO:0002715 19 0.941
t cell mediated cytotoxicity GO:0001913 26 0.929
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.916
antigen processing and presentation of peptide antigen via mhc class ib GO:0002428 5 0.913
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.898
natural killer cell mediated cytotoxicity GO:0042267 29 0.894
regulation of cell killing GO:0031341 40 0.889
positive regulation of t cell mediated immunity GO:0002711 24 0.859
positive regulation of cell killing GO:0031343 33 0.850
antigen processing and presentation of peptide antigen GO:0048002 29 0.826
regulation of defense response GO:0031347 233 0.822
regulation of t cell mediated immunity GO:0002709 34 0.821
leukocyte mediated cytotoxicity GO:0001909 62 0.767
antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway tap dependent GO:0002489 2 0.742
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 3 0.738
innate immune response GO:0045087 157 0.736
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 9 0.733
regulation of innate immune response GO:0045088 91 0.724
antigen processing and presentation GO:0019882 47 0.723
antigen processing and presentation of exogenous peptide antigen via mhc class ib GO:0002477 3 0.722
defense response to other organism GO:0098542 197 0.699
tolerance induction dependent upon immune response GO:0002461 1 0.641
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.607
response to protozoan GO:0001562 28 0.587
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.585
reactive nitrogen species metabolic process GO:2001057 0 0.582
lymphocyte mediated immunity GO:0002449 139 0.581
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.576
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.575
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway tap dependent GO:0002485 3 0.540
positive regulation of cytokine production GO:0001819 174 0.522
iron ion homeostasis GO:0055072 36 0.515
adaptive immune response GO:0002250 155 0.510
regulation of cytokine production GO:0001817 266 0.508
regulation of adaptive immune response GO:0002819 90 0.497
cell killing GO:0001906 67 0.495
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.492
natural killer cell mediated immunity GO:0002228 29 0.491
positive regulation of leukocyte mediated immunity GO:0002705 70 0.439
cytokine production GO:0001816 319 0.429
regulation of lymphocyte mediated immunity GO:0002706 84 0.420
antigen processing and presentation of endogenous peptide antigen GO:0002483 6 0.414
leukocyte mediated immunity GO:0002443 174 0.414
immune effector process GO:0002252 321 0.407
antigen processing and presentation of exogenous antigen GO:0019884 26 0.406
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.395
cation transport GO:0006812 399 0.393
defense response to bacterium GO:0042742 119 0.391
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.386
antigen processing and presentation of endogenous antigen GO:0019883 6 0.381
cellular response to interferon beta GO:0035458 21 0.380
transition metal ion transport GO:0000041 38 0.374
import into cell GO:0098657 8 0.366
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.365
interferon gamma production GO:0032609 67 0.364
positive regulation of innate immune response GO:0045089 80 0.360
t cell activation involved in immune response GO:0002286 43 0.356
regulation of reactive oxygen species metabolic process GO:2000377 40 0.346
positive regulation of immune effector process GO:0002699 107 0.345
interleukin 17 production GO:0032620 11 0.321
regulation of leukocyte mediated immunity GO:0002703 104 0.310
reactive oxygen species biosynthetic process GO:1903409 8 0.304
multicellular organismal homeostasis GO:0048871 164 0.297
response to molecule of bacterial origin GO:0002237 143 0.296
negative regulation of innate immune response GO:0045824 17 0.271
regulation of interferon gamma production GO:0032649 57 0.270
reactive oxygen species metabolic process GO:0072593 84 0.259
positive regulation of adaptive immune response GO:0002821 61 0.259
positive regulation of tolerance induction GO:0002645 8 0.251
antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway GO:0002488 2 0.244
ear development GO:0043583 200 0.242
negative regulation of defense response GO:0031348 77 0.238
positive regulation of defense response GO:0031349 124 0.232
leukocyte activation involved in immune response GO:0002366 126 0.225
inorganic cation import into cell GO:0098659 4 0.218
interleukin 1 production GO:0032612 31 0.213
metal ion homeostasis GO:0055065 189 0.197
defense response to gram negative bacterium GO:0050829 28 0.191
adhesion of symbiont to host GO:0044406 8 0.190
negative regulation of immune system process GO:0002683 209 0.188
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.187
multicellular organismal iron ion homeostasis GO:0060586 8 0.181
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.172
t cell tolerance induction GO:0002517 6 0.172
production of molecular mediator of immune response GO:0002440 103 0.172
interleukin 1 beta production GO:0032611 30 0.169
positive regulation of interferon gamma production GO:0032729 39 0.158
cytokine production involved in immune response GO:0002367 34 0.151
defense response to virus GO:0051607 68 0.146
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.142
transition metal ion homeostasis GO:0055076 54 0.136
alpha beta t cell activation GO:0046631 91 0.135
cell activation involved in immune response GO:0002263 126 0.133
cation homeostasis GO:0055080 212 0.131
alpha beta t cell activation involved in immune response GO:0002287 31 0.126
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.121
antigen processing and presentation of exogenous protein antigen via mhc class ib tap dependent GO:0002481 3 0.119
regulation of nitric oxide biosynthetic process GO:0045428 18 0.117
cellular response to cytokine stimulus GO:0071345 189 0.112
negative regulation of cell proliferation GO:0008285 296 0.111
lymphocyte activation involved in immune response GO:0002285 93 0.109
antigen processing and presentation of exogenous peptide antigen via mhc class i GO:0042590 6 0.108
nucleoside phosphate catabolic process GO:1901292 222 0.106
cellular response to interferon gamma GO:0071346 25 0.106
t cell activation GO:0042110 289 0.105
purine nucleoside triphosphate catabolic process GO:0009146 203 0.103
ribose phosphate metabolic process GO:0019693 291 0.101
organic cyclic compound catabolic process GO:1901361 295 0.099
nucleoside triphosphate catabolic process GO:0009143 205 0.096
nitric oxide metabolic process GO:0046209 25 0.096
purine containing compound catabolic process GO:0072523 213 0.095
purine ribonucleoside catabolic process GO:0046130 205 0.094
negative regulation of lymphocyte mediated immunity GO:0002707 21 0.093
carbohydrate derivative catabolic process GO:1901136 231 0.093
cellular response to lipopolysaccharide GO:0071222 77 0.092
gtp catabolic process GO:0006184 143 0.087
regulation of type i interferon production GO:0032479 22 0.082
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.082
cellular response to biotic stimulus GO:0071216 92 0.081
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.080
glycosyl compound metabolic process GO:1901657 246 0.079
guanosine containing compound catabolic process GO:1901069 144 0.079
gtp metabolic process GO:0046039 144 0.077
negative regulation of leukocyte mediated immunity GO:0002704 29 0.076
nucleoside phosphate metabolic process GO:0006753 338 0.076
hormone biosynthetic process GO:0042446 16 0.075
negative regulation of intracellular protein transport GO:0090317 27 0.072
hormone metabolic process GO:0042445 86 0.072
cellular amino acid metabolic process GO:0006520 103 0.072
tolerance induction GO:0002507 14 0.070
regulation of cytoplasmic transport GO:1903649 112 0.068
heterocycle catabolic process GO:0046700 280 0.065
cellular response to molecule of bacterial origin GO:0071219 83 0.065
nitric oxide biosynthetic process GO:0006809 25 0.063
nucleotide catabolic process GO:0009166 217 0.063
cellular ketone metabolic process GO:0042180 84 0.063
negative regulation of protein metabolic process GO:0051248 282 0.062
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.062
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.061
purine ribonucleoside metabolic process GO:0046128 241 0.060
response to interferon gamma GO:0034341 34 0.060
purine nucleotide metabolic process GO:0006163 302 0.060
negative regulation of protein modification process GO:0031400 163 0.059
defense response to gram positive bacterium GO:0050830 50 0.058
aromatic compound catabolic process GO:0019439 286 0.056
protein modification by small protein conjugation or removal GO:0070647 207 0.055
nucleoside triphosphate metabolic process GO:0009141 230 0.055
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 5 0.054
ribonucleoside triphosphate metabolic process GO:0009199 220 0.053
nucleotide metabolic process GO:0009117 332 0.053
purine nucleoside catabolic process GO:0006152 205 0.053
defense response to protozoan GO:0042832 25 0.052
interspecies interaction between organisms GO:0044419 83 0.051
purine ribonucleotide metabolic process GO:0009150 290 0.051
nucleoside metabolic process GO:0009116 246 0.050
nucleoside catabolic process GO:0009164 206 0.050
purine containing compound metabolic process GO:0072521 311 0.050
regulation of cellular ketone metabolic process GO:0010565 66 0.049
negative regulation of phosphorus metabolic process GO:0010563 184 0.048
purine nucleoside metabolic process GO:0042278 241 0.047
ribonucleoside triphosphate catabolic process GO:0009203 199 0.047
guanosine containing compound metabolic process GO:1901068 144 0.047
regulation of establishment of protein localization GO:0070201 181 0.047
protein localization to nucleus GO:0034504 121 0.046
protein ubiquitination GO:0016567 171 0.046
nucleobase containing small molecule metabolic process GO:0055086 352 0.045
organophosphate catabolic process GO:0046434 232 0.045
response to interferon beta GO:0035456 22 0.044
purine nucleoside triphosphate metabolic process GO:0009144 226 0.044
ribonucleoside metabolic process GO:0009119 245 0.044
ribonucleotide metabolic process GO:0009259 291 0.043
regulation of tolerance induction GO:0002643 10 0.043
regulation of protein ubiquitination GO:0031396 52 0.043
glycosyl compound catabolic process GO:1901658 206 0.042
organonitrogen compound catabolic process GO:1901565 264 0.042
lymphocyte differentiation GO:0030098 242 0.040
cellular response to lipid GO:0071396 145 0.040
regulation of interferon alpha production GO:0032647 5 0.040
response to lipopolysaccharide GO:0032496 128 0.039
negative regulation of immune effector process GO:0002698 55 0.039
negative regulation of phosphorylation GO:0042326 166 0.038
negative regulation of defense response to virus by host GO:0050689 1 0.038
protein refolding GO:0042026 1 0.037
iron ion transport GO:0006826 17 0.037
negative regulation of cell activation GO:0050866 111 0.036
protein import GO:0017038 101 0.036
cytoplasmic transport GO:0016482 234 0.035
ribonucleotide catabolic process GO:0009261 208 0.034
negative regulation of cellular protein metabolic process GO:0032269 247 0.034
viral life cycle GO:0019058 36 0.033
positive regulation of programmed cell death GO:0043068 218 0.032
protein localization to organelle GO:0033365 185 0.032
ribonucleoside catabolic process GO:0042454 206 0.031
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.030
purine ribonucleotide catabolic process GO:0009154 208 0.030
rho protein signal transduction GO:0007266 32 0.030
cellular amine metabolic process GO:0044106 44 0.029
regulation of lymphocyte activation GO:0051249 240 0.029
negative regulation of interferon beta biosynthetic process GO:0045358 1 0.029
epithelial tube morphogenesis GO:0060562 303 0.029
apoptotic signaling pathway GO:0097190 306 0.029
rna interference GO:0016246 2 0.028
establishment of protein localization to organelle GO:0072594 118 0.028
regulation of cellular amine metabolic process GO:0033238 20 0.028
protein import into nucleus GO:0006606 95 0.028
negative regulation of nucleocytoplasmic transport GO:0046823 23 0.028
type i interferon production GO:0032606 29 0.028
negative regulation of protein phosphorylation GO:0001933 126 0.027
inflammatory response GO:0006954 244 0.027
purine nucleotide catabolic process GO:0006195 211 0.027
regulation of protein targeting GO:1903533 61 0.027
regulation of intracellular protein transport GO:0033157 82 0.026
cell adhesion GO:0007155 329 0.025
cellular component assembly involved in morphogenesis GO:0010927 139 0.025
intracellular protein transport GO:0006886 204 0.025
regulation of hormone levels GO:0010817 211 0.025
response to organonitrogen compound GO:0010243 246 0.025
maintenance of location GO:0051235 89 0.024
regulation of cell adhesion GO:0030155 154 0.024
protein targeting GO:0006605 143 0.024
regulation of response to biotic stimulus GO:0002831 38 0.023
nucleocytoplasmic transport GO:0006913 139 0.023
epithelial cell proliferation GO:0050673 174 0.023
nitrogen compound transport GO:0071705 271 0.022
negative regulation of cytokine production GO:0001818 84 0.022
negative regulation of leukocyte differentiation GO:1902106 51 0.021
regulation of lipid metabolic process GO:0019216 118 0.021
regulation of multi organism process GO:0043900 111 0.021
inorganic ion import into cell GO:0099587 4 0.021
ossification GO:0001503 216 0.021
regulation of protein localization GO:0032880 231 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
muscle cell development GO:0055001 133 0.020
sequestering of calcium ion GO:0051208 18 0.020
developmental maturation GO:0021700 193 0.020
regulation of striated muscle cell differentiation GO:0051153 81 0.020
negative regulation of cell killing GO:0031342 8 0.019
leukocyte proliferation GO:0070661 172 0.019
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.019
sequestering of metal ion GO:0051238 19 0.019
actin cytoskeleton organization GO:0030036 220 0.018
negative regulation of interferon alpha production GO:0032687 1 0.018
blood vessel morphogenesis GO:0048514 285 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
g protein coupled receptor signaling pathway GO:0007186 243 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
regulation of intracellular transport GO:0032386 159 0.018
cellular nitrogen compound catabolic process GO:0044270 280 0.018
positive regulation of apoptotic process GO:0043065 217 0.017
regulation of defense response to virus GO:0050688 18 0.017
regulation of nucleocytoplasmic transport GO:0046822 73 0.017
syncytium formation by plasma membrane fusion GO:0000768 42 0.017
regulation of neuron apoptotic process GO:0043523 122 0.017
cell type specific apoptotic process GO:0097285 268 0.017
tissue homeostasis GO:0001894 115 0.017
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.017
regulation of defense response to fungus GO:1900150 1 0.017
response to organic cyclic compound GO:0014070 198 0.017
positive regulation of cellular amine metabolic process GO:0033240 5 0.017
amine metabolic process GO:0009308 45 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.016
negative regulation of epithelial cell proliferation GO:0050680 64 0.016
leukocyte differentiation GO:0002521 342 0.016
muscle tissue development GO:0060537 308 0.016
regulation of autophagy GO:0010506 30 0.016
regulation of protein transport GO:0051223 163 0.016
positive regulation of cell death GO:0010942 224 0.016
negative regulation of molecular function GO:0044092 258 0.015
cellular response to type i interferon GO:0071357 10 0.015
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.015
response to drug GO:0042493 75 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
positive regulation of interferon alpha production GO:0032727 4 0.015
amide transport GO:0042886 138 0.015
negative regulation of protein ubiquitination GO:0031397 19 0.015
regulation of hydrolase activity GO:0051336 246 0.015
myotube differentiation GO:0014902 105 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
sensory perception GO:0007600 245 0.015
cellular homeostasis GO:0019725 240 0.015
negative regulation of protein transport GO:0051224 46 0.015
response to amino acid GO:0043200 37 0.015
regulation of t cell activation GO:0050863 170 0.014
regulation of metal ion transport GO:0010959 106 0.014
regulation of myoblast differentiation GO:0045661 29 0.014
regulation of protein import into nucleus GO:0042306 52 0.014
protein catabolic process GO:0030163 221 0.014
regulation of ion transport GO:0043269 215 0.014
nuclear transport GO:0051169 139 0.014
glucose homeostasis GO:0042593 128 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
regulation of protein localization to nucleus GO:1900180 60 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.013
negative regulation of t cell activation GO:0050868 65 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
posttranscriptional gene silencing GO:0016441 10 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
calcium ion homeostasis GO:0055074 127 0.013
protein maturation GO:0051604 176 0.013
regulation of calcium ion transport GO:0051924 69 0.013
regulation of neutrophil mediated killing of symbiont cell GO:0070949 2 0.013
peptidyl tyrosine phosphorylation GO:0018108 143 0.013
negative regulation of intracellular transport GO:0032387 38 0.013
carbohydrate homeostasis GO:0033500 128 0.013
cellular chemical homeostasis GO:0055082 215 0.013
regulation of defense response to bacterium GO:1900424 3 0.013
regulation of secretion GO:0051046 274 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.012
anatomical structure homeostasis GO:0060249 145 0.012
regulation of proteolysis GO:0030162 164 0.012
protein methylation GO:0006479 81 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
positive regulation of rig i signaling pathway GO:1900246 1 0.012
myeloid cell differentiation GO:0030099 233 0.012
negative regulation of cytoplasmic transport GO:1903650 29 0.012
lysosomal transport GO:0007041 10 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
single organism nuclear import GO:1902593 95 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
positive regulation of phospholipase activity GO:0010518 3 0.012
macromolecule catabolic process GO:0009057 281 0.012
myosin filament organization GO:0031033 3 0.012
regulation of ion homeostasis GO:2000021 64 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
ras protein signal transduction GO:0007265 77 0.012
response to inorganic substance GO:0010035 96 0.012
activation of innate immune response GO:0002218 56 0.012
regulation of cellular amino acid metabolic process GO:0006521 5 0.011
positive regulation of antimicrobial humoral response GO:0002760 2 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
macromolecule methylation GO:0043414 120 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.011
glycoprotein metabolic process GO:0009100 116 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
nuclear import GO:0051170 95 0.011
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.011
viral transcription GO:0019083 3 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
autophagy GO:0006914 45 0.011
response to acid chemical GO:0001101 111 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
innate immune response activating signal transduction GO:0002758 50 0.011
t cell differentiation GO:0030217 174 0.011
regulation of viral transcription GO:0046782 3 0.011
muscle cell differentiation GO:0042692 261 0.011
antimicrobial peptide production GO:0002775 2 0.011
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.011
regulation of cell migration GO:0030334 219 0.010
peptide secretion GO:0002790 114 0.010
calcium ion transport GO:0006816 159 0.010
muscle fiber development GO:0048747 76 0.010
female sex differentiation GO:0046660 84 0.010
angiogenesis GO:0001525 201 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
regulation of ossification GO:0030278 112 0.010
histone modification GO:0016570 159 0.010
regulation of alpha beta t cell activation GO:0046634 53 0.010
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.010
skeletal muscle organ development GO:0060538 163 0.010
insulin secretion GO:0030073 89 0.010

H2-Q7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.017
disease of anatomical entity DOID:7 0 0.017
gastrointestinal system cancer DOID:3119 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
cancer DOID:162 0 0.013
hypersensitivity reaction disease DOID:0060056 0 0.012
immune system disease DOID:2914 0 0.012