Mus musculus

284 known processes

Hand2

heart and neural crest derivatives expressed transcript 2

(Aliases: Ehand2,Thing2,bHLHa26,AI661148,Th2,Hed,AI225906,dHAND)

Hand2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 1.000
positive regulation of transcription via serum response element binding GO:0010735 1 1.000
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 1.000
Mouse
embryonic organ morphogenesis GO:0048562 276 1.000
heart trabecula formation GO:0060347 14 1.000
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 1.000
auditory receptor cell fate determination GO:0042668 3 1.000
Mouse
ventricular cardiac myofibril assembly GO:0055005 3 1.000
clara cell differentiation GO:0060486 4 1.000
pancreatic pp cell fate commitment GO:0003329 2 1.000
Mouse
embryonic heart tube formation GO:0003144 1 1.000
Zebrafish Mouse
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 1.000
ventricular cardiac muscle cell differentiation GO:0055012 17 1.000
atrial cardiac muscle cell development GO:0055014 2 1.000
cardiac chamber morphogenesis GO:0003206 93 1.000
embryonic skeletal system development GO:0048706 120 1.000
Zebrafish Mouse
positive regulation of cardioblast differentiation GO:0051891 3 1.000
atrial cardiac muscle cell differentiation GO:0055011 2 1.000
mesenchyme development GO:0060485 152 1.000
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 1.000
Mouse
regulation of auditory receptor cell differentiation GO:0045607 4 1.000
Mouse
cardiac pacemaker cell fate commitment GO:0060927 1 1.000
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 1.000
Mouse
regionalization GO:0003002 337 1.000
Mouse
positive regulation of inner ear receptor cell differentiation GO:2000982 1 1.000
Mouse
spinal cord oligodendrocyte cell fate specification GO:0021530 3 1.000
endocardial cushion formation GO:0003272 13 1.000
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 1.000
endodermal cell fate commitment GO:0001711 12 1.000
embryonic heart tube left right pattern formation GO:0060971 5 1.000
cardiac ventricle morphogenesis GO:0003208 50 1.000
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 1.000
forebrain neuron fate commitment GO:0021877 13 1.000
cell fate specification GO:0001708 72 1.000
Mouse
cardiac muscle cell development GO:0055013 39 1.000
globus pallidus development GO:0021759 2 1.000
cardiocyte differentiation GO:0035051 87 1.000
cardioblast migration to the midline involved in heart field formation GO:0060975 1 1.000
sinoatrial node cell differentiation GO:0060921 3 1.000
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 1.000
endodermal cell fate specification GO:0001714 4 1.000
pyramidal neuron migration GO:0021852 1 1.000
cardiac muscle cell differentiation GO:0055007 69 1.000
striated muscle tissue development GO:0014706 293 1.000
Mouse
ear development GO:0043583 200 1.000
Mouse
epithelial tube morphogenesis GO:0060562 303 1.000
atrioventricular node cell development GO:0060928 2 1.000
cell fate commitment GO:0045165 210 1.000
Mouse
appendage morphogenesis GO:0035107 149 1.000
positive regulation of cardiac muscle cell proliferation GO:0060045 15 1.000
negative regulation of neuron differentiation GO:0045665 101 1.000
purkinje myocyte differentiation GO:0003168 1 1.000
axon guidance GO:0007411 141 1.000
Mouse
locus ceruleus development GO:0021703 1 1.000
midbrain hindbrain boundary morphogenesis GO:0021555 4 1.000
regulation of cardiac muscle tissue development GO:0055024 31 1.000
regulation of heart morphogenesis GO:2000826 22 1.000
regulation of mast cell differentiation GO:0060375 3 0.999
Mouse
ventral spinal cord interneuron fate determination GO:0060580 1 0.999
ventricular cardiac muscle cell development GO:0055015 11 0.999
cardiac epithelial to mesenchymal transition GO:0060317 18 0.999
Mouse
metanephric capsule specification GO:0072267 1 0.999
pituitary gland development GO:0021983 38 0.999
nephron tubule morphogenesis GO:0072078 68 0.999
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.999
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.999
epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198 10 0.999
atrioventricular node cell fate commitment GO:0060929 1 0.999
oligodendrocyte development GO:0014003 20 0.999
regulation of cardiac muscle cell proliferation GO:0060043 23 0.999
atrioventricular node cell differentiation GO:0060922 2 0.999
diencephalon development GO:0021536 63 0.999
Mouse
neuron projection guidance GO:0097485 141 0.999
Mouse
mitral valve morphogenesis GO:0003183 4 0.999
Mouse
regulation of cardioblast differentiation GO:0051890 3 0.999
heart field specification GO:0003128 6 0.999
stem cell development GO:0048864 219 0.999
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.999
telencephalon development GO:0021537 186 0.999
Mouse
cardiac ventricle development GO:0003231 83 0.999
oligodendrocyte cell fate commitment GO:0021779 5 0.999
bmp signaling pathway GO:0030509 93 0.999
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.999
Mouse
cardiac cell fate determination GO:0060913 2 0.999
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.999
astrocyte fate commitment GO:0060018 4 0.999
Mouse
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.999
cerebral cortex neuron differentiation GO:0021895 19 0.999
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.999
Mouse
cardiac right ventricle formation GO:0003219 3 0.999
regulation of endodermal cell fate specification GO:0042663 2 0.999
somitogenesis GO:0001756 69 0.999
Mouse
skeletal system development GO:0001501 356 0.999
heart valve formation GO:0003188 10 0.999
Mouse
negative regulation of cell development GO:0010721 169 0.998
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.998
negative regulation of muscle cell apoptotic process GO:0010656 9 0.998
cardiac muscle tissue development GO:0048738 130 0.998
Mouse
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.998
stem cell differentiation GO:0048863 268 0.998
embryonic heart tube anterior posterior pattern specification GO:0035054 3 0.998
ventricular septum morphogenesis GO:0060412 27 0.998
muscle tissue development GO:0060537 308 0.998
Mouse
trachea formation GO:0060440 3 0.998
tricuspid valve development GO:0003175 3 0.998
cardioblast migration GO:0003260 1 0.998
regulation of cardiac muscle tissue growth GO:0055021 26 0.998
negative regulation of striated muscle cell apoptotic process GO:0010664 8 0.998
ventricular trabecula myocardium morphogenesis GO:0003222 11 0.998
neural tube closure GO:0001843 90 0.998
Mouse
forebrain neuron differentiation GO:0021879 52 0.998
coronary vasculature development GO:0060976 12 0.997
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.997
Fly
noradrenergic neuron differentiation GO:0003357 6 0.997
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.997
embryonic viscerocranium morphogenesis GO:0048703 8 0.997
Zebrafish
blood vessel morphogenesis GO:0048514 285 0.997
bundle of his development GO:0003166 4 0.997
cell migration to the midline involved in heart development GO:0003318 1 0.997
mesenchyme morphogenesis GO:0072132 32 0.997
Mouse
morphogenesis of a branching structure GO:0001763 203 0.997
cardiac myofibril assembly GO:0055003 12 0.997
mesenchymal cell development GO:0014031 93 0.997
heart trabecula morphogenesis GO:0061384 26 0.997
mesenchymal cell differentiation GO:0048762 107 0.997
positive regulation of heart growth GO:0060421 18 0.997
inner ear receptor cell differentiation GO:0060113 61 0.997
Mouse
skeletal muscle cell differentiation GO:0035914 66 0.996
Mouse
tendon formation GO:0035992 4 0.996
Mouse
endochondral bone morphogenesis GO:0060350 50 0.996
Mouse
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.996
endocardial cushion morphogenesis GO:0003203 18 0.996
Mouse
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.996
telencephalon regionalization GO:0021978 14 0.996
cardiac chamber development GO:0003205 108 0.996
his purkinje system cell differentiation GO:0060932 2 0.996
nephron morphogenesis GO:0072028 69 0.996
regulation of endodermal cell differentiation GO:1903224 2 0.996
astrocyte differentiation GO:0048708 43 0.996
Mouse
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.996
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.996
trophectodermal cell differentiation GO:0001829 21 0.996
negative regulation of gastrulation GO:2000542 3 0.996
spinal cord development GO:0021510 81 0.996
Mouse
embryonic placenta development GO:0001892 98 0.996
Mouse
cardiac atrium morphogenesis GO:0003209 23 0.995
neuron fate specification GO:0048665 30 0.995
Mouse
septum primum development GO:0003284 4 0.995
tendon cell differentiation GO:0035990 4 0.995
Mouse
glial cell fate specification GO:0021780 5 0.995
neuron fate determination GO:0048664 9 0.995
Mouse
cardiac septum development GO:0003279 59 0.995
hindbrain development GO:0030902 128 0.995
Mouse
renal capsule specification GO:0072130 1 0.995
endothelial cell differentiation GO:0045446 41 0.995
hemangioblast cell differentiation GO:0060217 1 0.995
Mouse
gabaergic neuron differentiation GO:0097154 11 0.995
respiratory system development GO:0060541 190 0.994
regulation of system process GO:0044057 200 0.994
Mouse
inner ear morphogenesis GO:0042472 101 0.994
Mouse
closure of optic fissure GO:0061386 2 0.994
aorta morphogenesis GO:0035909 22 0.994
embryonic epithelial tube formation GO:0001838 130 0.994
Zebrafish Mouse
positive regulation of nervous system development GO:0051962 221 0.994
Mouse
auditory receptor cell fate specification GO:0042667 1 0.994
Mouse
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.994
oligodendrocyte differentiation GO:0048709 53 0.994
hindlimb morphogenesis GO:0035137 42 0.993
Mouse
positive regulation of transcription by glucose GO:0046016 3 0.993
cerebral cortex cell migration GO:0021795 44 0.993
heart growth GO:0060419 45 0.993
specification of organ identity GO:0010092 30 0.993
branching morphogenesis of an epithelial tube GO:0048754 159 0.993
cell proliferation in hindbrain GO:0021534 10 0.993
striated muscle cell proliferation GO:0014855 39 0.993
mesonephric tubule development GO:0072164 94 0.993
regulation of glial cell differentiation GO:0045685 41 0.993
forebrain regionalization GO:0021871 25 0.993
oculomotor nerve morphogenesis GO:0021622 2 0.992
ear morphogenesis GO:0042471 118 0.992
Mouse
regulation of heart growth GO:0060420 31 0.992
cardiac muscle cell apoptotic process GO:0010659 10 0.992
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.992
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.992
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.992
limb morphogenesis GO:0035108 149 0.992
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.991
Mouse
sensory organ morphogenesis GO:0090596 242 0.991
Mouse
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.991
proepicardium development GO:0003342 2 0.991
Zebrafish
cardiac atrium development GO:0003230 24 0.991
ventricular cardiac muscle tissue development GO:0003229 38 0.991
Mouse
negative regulation of cardiac muscle cell apoptotic process GO:0010667 6 0.990
atrial septum development GO:0003283 12 0.990
embryonic camera type eye development GO:0031076 36 0.990
mitral valve development GO:0003174 4 0.990
Mouse
muscle tissue morphogenesis GO:0060415 53 0.990
Mouse
cartilage development GO:0051216 140 0.990
cardiac cell development GO:0055006 41 0.990
neural crest cell differentiation GO:0014033 54 0.990
endocardial cushion to mesenchymal transition GO:0090500 5 0.990
Mouse
cardiac septum morphogenesis GO:0060411 46 0.989
embryonic heart tube development GO:0035050 65 0.989
limb development GO:0060173 166 0.989
atrioventricular valve morphogenesis GO:0003181 13 0.989
Mouse
oligodendrocyte cell fate specification GO:0021778 5 0.989
aortic valve morphogenesis GO:0003180 4 0.989
Mouse
kidney morphogenesis GO:0060993 83 0.989
his purkinje system development GO:0003164 4 0.988
heart valve morphogenesis GO:0003179 21 0.988
Mouse
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.988
pallium development GO:0021543 120 0.987
Mouse
atrial septum primum morphogenesis GO:0003289 3 0.987
hindbrain tangential cell migration GO:0021934 2 0.987
epithelial cell proliferation GO:0050673 174 0.987
Mouse
ureteric bud morphogenesis GO:0060675 62 0.987
pericardium development GO:0060039 16 0.987
peripheral nervous system neuron axonogenesis GO:0048936 3 0.987
regulation of astrocyte differentiation GO:0048710 20 0.986
limbic system development GO:0021761 72 0.986
Mouse
negative regulation of nervous system development GO:0051961 156 0.986
Mouse
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.986
positive regulation of ureteric bud formation GO:0072107 3 0.986
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.985
atrial ventricular junction remodeling GO:0003294 2 0.985
hair cell differentiation GO:0035315 40 0.985
Mouse
regulation of neuron differentiation GO:0045664 281 0.985
Mouse
endothelium development GO:0003158 45 0.984
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.984
cardiac chamber formation GO:0003207 10 0.983
positive regulation of glial cell differentiation GO:0045687 21 0.983
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.983
lateral motor column neuron migration GO:0097477 3 0.983
embryonic eye morphogenesis GO:0048048 29 0.983
neuron migration GO:0001764 122 0.983
Mouse
neural crest cell development GO:0014032 48 0.982
endocardial cell differentiation GO:0060956 4 0.982
glial cell fate commitment GO:0021781 14 0.982
Mouse
determination of heart left right asymmetry GO:0061371 48 0.981
cardiac ventricle formation GO:0003211 8 0.981
axial mesodermal cell fate commitment GO:0048322 1 0.981
cardiac conduction system development GO:0003161 12 0.981
regulation of stem cell maintenance GO:2000036 17 0.981
Mouse
artery development GO:0060840 53 0.980
embryonic heart tube morphogenesis GO:0003143 51 0.980
embryonic skeletal system morphogenesis GO:0048704 91 0.980
Zebrafish Mouse
lung development GO:0030324 164 0.980
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.980
Mouse
neural crest cell migration GO:0001755 32 0.979
pancreatic pp cell differentiation GO:0003312 2 0.979
Mouse
spinal cord association neuron differentiation GO:0021527 14 0.979
Mouse
mechanoreceptor differentiation GO:0042490 67 0.979
Mouse
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.979
regulation of heart contraction GO:0008016 77 0.978
mesonephros development GO:0001823 97 0.978
regulation of gastrulation GO:0010470 16 0.977
Mouse
mesonephric tubule morphogenesis GO:0072171 63 0.977
muscle cell development GO:0055001 133 0.977
s shaped body morphogenesis GO:0072050 6 0.977
regulation of organ formation GO:0003156 34 0.977
branching involved in ureteric bud morphogenesis GO:0001658 56 0.976
blastocyst formation GO:0001825 33 0.976
renal system development GO:0072001 225 0.976
mesonephric epithelium development GO:0072163 94 0.976
cerebral cortex tangential migration GO:0021800 7 0.976
spinal cord motor neuron differentiation GO:0021522 35 0.975
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.975
ureteric bud development GO:0001657 94 0.974
cerebral cortex gabaergic interneuron fate commitment GO:0021893 2 0.974
nephron epithelium morphogenesis GO:0072088 68 0.973
urogenital system development GO:0001655 261 0.973
forebrain generation of neurons GO:0021872 63 0.973
regulation of ureteric bud formation GO:0072106 3 0.973
ascending aorta morphogenesis GO:0035910 3 0.973
circulatory system process GO:0003013 197 0.973
Zebrafish
noradrenergic neuron development GO:0003358 3 0.972
cardiac muscle cell proliferation GO:0060038 31 0.971
regulation of organ morphogenesis GO:2000027 144 0.971
menarche GO:0042696 1 0.971
positive regulation of cardiac muscle tissue development GO:0055025 19 0.970
forebrain development GO:0030900 302 0.970
Mouse
cardiac left ventricle formation GO:0003218 1 0.970
mesoderm morphogenesis GO:0048332 64 0.970
Mouse
endothelial cell fate commitment GO:0060839 2 0.970
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.970
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.969
muscle cell proliferation GO:0033002 52 0.969
regulation of epithelial cell proliferation GO:0050678 141 0.969
Mouse
central nervous system neuron differentiation GO:0021953 162 0.968
Mouse
outflow tract septum morphogenesis GO:0003148 11 0.968
endocardial cushion development GO:0003197 26 0.968
Mouse
subpallium neuron fate commitment GO:0060163 2 0.967
kidney development GO:0001822 213 0.967
cerebellar granule cell precursor proliferation GO:0021930 10 0.967
erythrocyte maturation GO:0043249 6 0.966
Mouse
prostate gland stromal morphogenesis GO:0060741 2 0.966
regulation of transcription from rna polymerase ii promoter involved in forebrain neuron fate commitment GO:0021882 3 0.965
negative regulation of endodermal cell differentiation GO:1903225 1 0.965
cardiac muscle tissue growth GO:0055017 37 0.965
semicircular canal formation GO:0060876 1 0.965
erythrocyte differentiation GO:0030218 88 0.963
Mouse
spinal cord motor neuron migration GO:0097476 4 0.963
response to growth factor GO:0070848 198 0.962
Mouse
megakaryocyte differentiation GO:0030219 26 0.962
Mouse
lens morphogenesis in camera type eye GO:0002089 24 0.962
regulation of epidermal cell differentiation GO:0045604 21 0.961
Mouse
cardiac left ventricle morphogenesis GO:0003214 9 0.961
morphogenesis of a branching epithelium GO:0061138 193 0.961
striated muscle cell development GO:0055002 125 0.960
vascular wound healing GO:0061042 3 0.960
regulation of striated muscle cell apoptotic process GO:0010662 11 0.960
skeletal muscle organ development GO:0060538 163 0.959
Mouse
kidney epithelium development GO:0072073 121 0.959
regulation of cardiac muscle cell apoptotic process GO:0010665 9 0.959
negative regulation of endodermal cell fate specification GO:0042664 1 0.959
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.958
cardiac pacemaker cell development GO:0060926 5 0.958
positive regulation of axon extension GO:0045773 20 0.957
regulation of cell proliferation involved in heart morphogenesis GO:2000136 15 0.956
atrioventricular node development GO:0003162 3 0.956
cell differentiation involved in embryonic placenta development GO:0060706 26 0.955
Mouse
embryonic appendage morphogenesis GO:0035113 126 0.954
bone development GO:0060348 120 0.954
Mouse
positive regulation of stem cell proliferation GO:2000648 59 0.953
segmentation GO:0035282 93 0.953
Mouse
mesoderm development GO:0007498 100 0.953
Mouse
endocrine system development GO:0035270 98 0.952
Zebrafish Mouse
camera type eye development GO:0043010 266 0.951
Mouse
corticotropin hormone secreting cell differentiation GO:0060128 3 0.951
axonogenesis involved in innervation GO:0060385 5 0.951
organ growth GO:0035265 117 0.950
development of primary sexual characteristics GO:0045137 143 0.950
Worm
cell migration involved in heart development GO:0060973 8 0.950
muscle system process GO:0003012 141 0.949
appendage development GO:0048736 166 0.949
cardiac pacemaker cell differentiation GO:0060920 5 0.948
regulation of gliogenesis GO:0014013 50 0.948
specification of organ position GO:0010159 3 0.947
stem cell maintenance GO:0019827 130 0.947
Mouse
placenta development GO:0001890 140 0.946
Mouse
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.946
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.946
Mouse
regulation of neuroblast proliferation GO:1902692 27 0.945
negative regulation of cell fate specification GO:0009996 4 0.945
blood circulation GO:0008015 195 0.944
Zebrafish
coronary vasculature morphogenesis GO:0060977 9 0.944
glial cell differentiation GO:0010001 131 0.944
Mouse
olfactory lobe development GO:0021988 32 0.944
atrial septum morphogenesis GO:0060413 11 0.944
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.943
lens development in camera type eye GO:0002088 62 0.942
male sex differentiation GO:0046661 109 0.942
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.942
pulmonary myocardium development GO:0003350 3 0.942
metanephric capsule formation GO:0072266 1 0.941
regulation of muscle tissue development GO:1901861 97 0.941
Mouse
response to bmp GO:0071772 14 0.941
Mouse
paraxial mesodermal cell differentiation GO:0048342 2 0.940
pulmonary valve development GO:0003177 5 0.940
columnar cuboidal epithelial cell development GO:0002066 29 0.940
ectoderm formation GO:0001705 3 0.940
cerebral cortex development GO:0021987 86 0.940
Mouse
regulation of apoptotic process involved in morphogenesis GO:1902337 10 0.940
secondary heart field specification GO:0003139 6 0.939
cell fate determination GO:0001709 32 0.939
Mouse
endocrine pancreas development GO:0031018 29 0.939
Mouse
trophoblast giant cell differentiation GO:0060707 15 0.937
Mouse
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.936
ventral spinal cord interneuron fate commitment GO:0060579 14 0.935
positive regulation of cell development GO:0010720 237 0.935
Mouse
rhombomere 3 morphogenesis GO:0021658 2 0.934
cranial nerve development GO:0021545 41 0.934
ventral spinal cord interneuron differentiation GO:0021514 16 0.934
positive regulation of dna templated transcription elongation GO:0032786 2 0.934
Fly
auditory receptor cell differentiation GO:0042491 37 0.932
Mouse
hypothalamus development GO:0021854 16 0.931
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.931
cardiogenic plate morphogenesis GO:0003142 1 0.930
Zebrafish
connective tissue development GO:0061448 179 0.929
bone morphogenesis GO:0060349 78 0.929
Mouse
negative regulation of epithelial cell proliferation GO:0050680 64 0.928
megakaryocyte development GO:0035855 15 0.928
Mouse
positive regulation of angiogenesis GO:0045766 46 0.926
middle ear morphogenesis GO:0042474 23 0.925
chondrocyte development GO:0002063 24 0.925
deltoid tuberosity development GO:0035993 3 0.919
Mouse
vascular smooth muscle cell differentiation GO:0035886 11 0.918
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.917
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.917
regulation of bmp signaling pathway GO:0030510 60 0.917
cell differentiation in spinal cord GO:0021515 53 0.917
Mouse
visceral serous pericardium development GO:0061032 2 0.917
lung epithelial cell differentiation GO:0060487 29 0.915
cellular response to bmp stimulus GO:0071773 14 0.915
Mouse
hypothalamus cell migration GO:0021855 5 0.915
negative regulation of stem cell maintenance GO:1902455 4 0.914
regulation of vascular wound healing GO:0061043 2 0.914
negative regulation of astrocyte differentiation GO:0048712 10 0.913
venous blood vessel development GO:0060841 13 0.913
rhombomere 2 development GO:0021568 2 0.913
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.910
Mouse
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.909
subpallium development GO:0021544 20 0.909
epidermis development GO:0008544 187 0.909
Mouse
regulation of neuron maturation GO:0014041 5 0.909
regulation of mechanoreceptor differentiation GO:0045631 5 0.909
Mouse
forebrain morphogenesis GO:0048853 17 0.908
positive regulation of vascular wound healing GO:0035470 1 0.908
type b pancreatic cell fate commitment GO:0003327 1 0.908
cardioblast differentiation GO:0010002 13 0.907
Zebrafish
renal tubule development GO:0061326 87 0.907
nephrogenic mesenchyme development GO:0072076 3 0.906
cardiac endothelial cell differentiation GO:0003348 4 0.905
motor neuron migration GO:0097475 4 0.905
face morphogenesis GO:0060325 29 0.905
Mouse
respiratory tube development GO:0030323 167 0.904
medulla oblongata development GO:0021550 3 0.904
regulation of inner ear receptor cell differentiation GO:2000980 5 0.903
Mouse
lung induction GO:0060492 3 0.903
peripheral nervous system neuron differentiation GO:0048934 9 0.903
heart morphogenesis GO:0003007 178 0.902
pattern specification involved in metanephros development GO:0072268 4 0.902
muscle cell differentiation GO:0042692 261 0.902
sinoatrial node development GO:0003163 4 0.902
muscle adaptation GO:0043500 39 0.901
rhombomere morphogenesis GO:0021593 2 0.901
aorta development GO:0035904 23 0.899
tube formation GO:0035148 140 0.899
Zebrafish Mouse
forebrain cell migration GO:0021885 58 0.899
glial cell development GO:0021782 54 0.898
negative regulation of apoptotic process involved in morphogenesis GO:1902338 6 0.897
midbrain hindbrain boundary maturation GO:0021732 1 0.895
primary neural tube formation GO:0014020 95 0.895
Mouse
regulation of blood circulation GO:1903522 93 0.895
epithelial cell fate commitment GO:0072148 13 0.895
Mouse
forebrain neuron development GO:0021884 30 0.895
cell proliferation in external granule layer GO:0021924 10 0.894
somite rostral caudal axis specification GO:0032525 13 0.893
lung cell differentiation GO:0060479 30 0.893
autonomic nervous system development GO:0048483 43 0.893
regulation of myotube differentiation GO:0010830 62 0.893
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.892
mesenchymal cell proliferation involved in ureter development GO:0072198 4 0.892
heart formation GO:0060914 16 0.890
type b pancreatic cell differentiation GO:0003309 13 0.890
pancreas development GO:0031016 57 0.889
Mouse
endoderm formation GO:0001706 20 0.889
cardiac cell fate commitment GO:0060911 10 0.887
multicellular organism growth GO:0035264 161 0.887
Mouse
positive regulation of odontogenesis GO:0042482 4 0.887
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.886
regulation of cellular amine metabolic process GO:0033238 20 0.886
positive regulation of neuroblast proliferation GO:0002052 19 0.885
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.885
osteoblast development GO:0002076 17 0.884
regulation of muscle cell apoptotic process GO:0010660 17 0.884
otic placode formation GO:0043049 1 0.884
commitment of multipotent stem cells to neuronal lineage in forebrain GO:0021898 3 0.883
mast cell differentiation GO:0060374 5 0.883
Mouse
neuroepithelial cell differentiation GO:0060563 37 0.881
mesoderm formation GO:0001707 62 0.881
Mouse
neural tube formation GO:0001841 108 0.881
Mouse
cerebellar cortex development GO:0021695 48 0.879
Mouse
regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation GO:2000702 1 0.879
regulation of transcription involved in cell fate commitment GO:0060850 15 0.879
cell proliferation involved in heart morphogenesis GO:0061323 15 0.878
notch signaling pathway GO:0007219 71 0.877
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.875
Mouse
regulation of epithelial to mesenchymal transition GO:0010717 22 0.875
Mouse
cell differentiation in hindbrain GO:0021533 24 0.875
negative regulation of gliogenesis GO:0014014 23 0.875
negative regulation of dna binding GO:0043392 20 0.874
axonogenesis GO:0007409 274 0.874
Mouse
digestive system development GO:0055123 200 0.873
Zebrafish Mouse
spinal cord dorsal ventral patterning GO:0021513 23 0.873
nephric duct formation GO:0072179 4 0.873
regulation of skeletal muscle fiber development GO:0048742 36 0.871
atrioventricular bundle cell differentiation GO:0003167 1 0.870
prostate gland morphogenesis GO:0060512 32 0.870
renal capsule formation GO:0072129 1 0.869
bmp signaling pathway involved in heart development GO:0061312 2 0.869
primary prostatic bud elongation GO:0060516 2 0.868
negative regulation of glial cell differentiation GO:0045686 21 0.867
regulation of osteoblast differentiation GO:0045667 67 0.866
negative regulation of heart looping GO:1901208 1 0.865
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.865
developmental induction GO:0031128 34 0.864
platelet morphogenesis GO:0036344 13 0.863
Mouse
negative regulation of prostatic bud formation GO:0060686 4 0.861
regulation of mesodermal cell fate specification GO:0042661 5 0.860
embryonic forelimb morphogenesis GO:0035115 32 0.858
Mouse
heart valve development GO:0003170 23 0.858
Mouse
glandular epithelial cell differentiation GO:0002067 38 0.857
Mouse
paraxial mesodermal cell fate commitment GO:0048343 2 0.856
heart induction GO:0003129 2 0.855

Hand2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.978
musculoskeletal system disease DOID:17 0 0.978
heart disease DOID:114 0 0.923
cardiovascular system disease DOID:1287 0 0.923