Mus musculus

191 known processes

Hap1

huntingtin-associated protein 1

(Aliases: HAP-1,MGC31449)

Hap1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
microtubule based movement GO:0007018 84 0.493
vesicle transport along microtubule GO:0047496 9 0.342
vesicle localization GO:0051648 86 0.318
establishment of organelle localization GO:0051656 122 0.298
organelle assembly GO:0070925 177 0.285
establishment of vesicle localization GO:0051650 81 0.270
regulation of intracellular transport GO:0032386 159 0.210
transmembrane transport GO:0055085 412 0.209
regulation of cell motility GO:2000145 236 0.198
synaptic transmission GO:0007268 329 0.184
axon cargo transport GO:0008088 33 0.183
positive regulation of necrotic cell death GO:0010940 1 0.153
cation transport GO:0006812 399 0.151
organelle localization GO:0051640 179 0.142
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.139
single organismal cell cell adhesion GO:0016337 131 0.137
establishment of mitochondrion localization GO:0051654 4 0.132
Fly
cytoplasmic transport GO:0016482 234 0.131
regulation of hydrolase activity GO:0051336 246 0.130
chemotaxis GO:0006935 247 0.128
protein catabolic process GO:0030163 221 0.128
regulation of cell migration GO:0030334 219 0.127
positive regulation of cell activation GO:0050867 158 0.122
synaptic vesicle localization GO:0097479 59 0.122
microtubule based transport GO:0010970 50 0.119
cytoskeleton dependent intracellular transport GO:0030705 50 0.117
regulation of cellular component biogenesis GO:0044087 181 0.117
sensory organ morphogenesis GO:0090596 242 0.113
organic cyclic compound catabolic process GO:1901361 295 0.113
eye photoreceptor cell differentiation GO:0001754 41 0.107
positive regulation of nervous system development GO:0051962 221 0.103
actin filament organization GO:0007015 113 0.102
mapk cascade GO:0000165 281 0.102
ear development GO:0043583 200 0.099
synaptic vesicle transport GO:0048489 57 0.096
t cell activation GO:0042110 289 0.096
regulation of kinase activity GO:0043549 249 0.093
positive regulation of cell death GO:0010942 224 0.093
myeloid cell differentiation GO:0030099 233 0.093
macromolecule catabolic process GO:0009057 281 0.090
dendrite development GO:0016358 115 0.090
peptidyl tyrosine modification GO:0018212 145 0.089
ras protein signal transduction GO:0007265 77 0.084
leukocyte mediated immunity GO:0002443 174 0.083
cell adhesion GO:0007155 329 0.082
organelle disassembly GO:1903008 2 0.080
negative regulation of phosphorylation GO:0042326 166 0.080
photoreceptor cell differentiation GO:0046530 52 0.079
protein localization to organelle GO:0033365 185 0.078
regulation of protein kinase activity GO:0045859 232 0.074
calcium ion transport GO:0006816 159 0.074
epidermis development GO:0008544 187 0.074
regulation of leukocyte proliferation GO:0070663 121 0.074
regulation of proteolysis GO:0030162 164 0.074
actin cytoskeleton organization GO:0030036 220 0.074
cellular amino acid metabolic process GO:0006520 103 0.073
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 4 0.073
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.072
intracellular protein transport GO:0006886 204 0.071
nucleoside catabolic process GO:0009164 206 0.070
regulation of protein localization GO:0032880 231 0.070
cation transmembrane transport GO:0098655 266 0.070
purine ribonucleoside catabolic process GO:0046130 205 0.068
nucleoside triphosphate metabolic process GO:0009141 230 0.067
regulation of endopeptidase activity GO:0052548 89 0.067
regulation of cell projection organization GO:0031344 206 0.066
cellular amine metabolic process GO:0044106 44 0.066
regulation of peptidase activity GO:0052547 96 0.065
regulation of secretion by cell GO:1903530 249 0.065
negative regulation of protein metabolic process GO:0051248 282 0.064
endocytosis GO:0006897 168 0.064
ribonucleoprotein complex disassembly GO:0032988 3 0.064
spermatogenesis GO:0007283 284 0.063
Fly
response to oxidative stress GO:0006979 123 0.063
sensory perception GO:0007600 245 0.062
regulation of transferase activity GO:0051338 263 0.062
negative regulation of phosphorus metabolic process GO:0010563 184 0.061
plus end directed organelle transport along microtubule GO:0072386 2 0.061
microtubule based process GO:0007017 236 0.061
lysine transport GO:0015819 2 0.061
positive regulation of programmed cell death GO:0043068 218 0.060
cell type specific apoptotic process GO:0097285 268 0.060
regulation of lymphocyte proliferation GO:0050670 117 0.059
regulation of cellular amine metabolic process GO:0033238 20 0.059
glycosyl compound metabolic process GO:1901657 246 0.059
neuron projection guidance GO:0097485 141 0.059
olfactory learning GO:0008355 2 0.058
purine nucleoside triphosphate metabolic process GO:0009144 226 0.058
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.057
carbohydrate derivative catabolic process GO:1901136 231 0.057
oocyte construction GO:0007308 2 0.056
Fly
multicellular organismal homeostasis GO:0048871 164 0.056
regulation of lymphocyte activation GO:0051249 240 0.056
regulation of neuron projection development GO:0010975 169 0.055
regulation of cell adhesion GO:0030155 154 0.055
regulation of cell activation GO:0050865 289 0.055
lymphocyte proliferation GO:0046651 164 0.055
gtp metabolic process GO:0046039 144 0.055
regulation of vesicle mediated transport GO:0060627 139 0.055
organonitrogen compound catabolic process GO:1901565 264 0.055
nitrogen compound transport GO:0071705 271 0.054
heterocycle catabolic process GO:0046700 280 0.054
synaptic transmission gabaergic GO:0051932 19 0.053
purine ribonucleoside metabolic process GO:0046128 241 0.053
regulation of ion transport GO:0043269 215 0.052
germ cell development GO:0007281 185 0.051
Fly
response to steroid hormone GO:0048545 56 0.051
negative regulation of cell proliferation GO:0008285 296 0.050
cellular homeostasis GO:0019725 240 0.049
muscle cell differentiation GO:0042692 261 0.049
ribonucleoside triphosphate metabolic process GO:0009199 220 0.049
nucleotide metabolic process GO:0009117 332 0.049
regulation of neuron differentiation GO:0045664 281 0.048
positive regulation of secretion GO:0051047 130 0.048
response to light stimulus GO:0009416 135 0.048
positive regulation of hydrolase activity GO:0051345 148 0.048
plasma membrane organization GO:0007009 90 0.048
oocyte axis specification GO:0007309 2 0.047
Fly
purine nucleoside metabolic process GO:0042278 241 0.047
nuclear division GO:0000280 158 0.047
positive regulation of secretion by cell GO:1903532 114 0.047
neural tube development GO:0021915 160 0.047
organophosphate catabolic process GO:0046434 232 0.047
organelle fission GO:0048285 170 0.047
positive regulation of mapk cascade GO:0043410 170 0.047
regulation of synaptic transmission gabaergic GO:0032228 17 0.047
nucleoside phosphate metabolic process GO:0006753 338 0.047
energy derivation by oxidation of organic compounds GO:0015980 77 0.046
multicellular organismal signaling GO:0035637 91 0.046
cerebellar granule cell precursor tangential migration GO:0021935 1 0.046
skin development GO:0043588 220 0.046
regulation of nucleotide metabolic process GO:0006140 169 0.046
pole plasm assembly GO:0007315 2 0.046
purine nucleotide catabolic process GO:0006195 211 0.045
extracellular matrix organization GO:0030198 147 0.045
leukocyte apoptotic process GO:0071887 71 0.044
regulation of actin filament based process GO:0032970 99 0.044
meiotic nuclear division GO:0007126 115 0.044
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.044
regulation of t cell activation GO:0050863 170 0.043
learning GO:0007612 98 0.043
regulation of secretion GO:0051046 274 0.043
generation of precursor metabolites and energy GO:0006091 103 0.043
regulation of purine nucleotide metabolic process GO:1900542 169 0.043
cell division GO:0051301 120 0.042
positive regulation of protein phosphorylation GO:0001934 242 0.042
regulation of cellular response to stress GO:0080135 159 0.042
amine metabolic process GO:0009308 45 0.042
calcium ion homeostasis GO:0055074 127 0.041
leukocyte homeostasis GO:0001776 79 0.041
urogenital system development GO:0001655 261 0.041
cation homeostasis GO:0055080 212 0.041
forebrain development GO:0030900 302 0.041
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.041
nuclear transport GO:0051169 139 0.040
positive regulation of cell migration GO:0030335 109 0.040
nucleobase containing small molecule metabolic process GO:0055086 352 0.040
nucleoside triphosphate catabolic process GO:0009143 205 0.040
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.040
cell chemotaxis GO:0060326 81 0.040
establishment of synaptic vesicle localization GO:0097480 57 0.039
regulation of establishment of protein localization GO:0070201 181 0.039
extracellular structure organization GO:0043062 148 0.039
response to extracellular stimulus GO:0009991 127 0.039
positive regulation of neuron projection development GO:0010976 79 0.039
glycosyl compound catabolic process GO:1901658 206 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.038
regulation of cellular amino acid metabolic process GO:0006521 5 0.038
microtubule cytoskeleton organization GO:0000226 157 0.038
plus end directed vesicle transport along microtubule GO:0072383 2 0.038
guanosine containing compound catabolic process GO:1901069 144 0.038
spermatid development GO:0007286 108 0.037
Fly
regulation of cytoplasmic transport GO:1903649 112 0.037
negative regulation of nervous system development GO:0051961 156 0.037
cellular nitrogen compound catabolic process GO:0044270 280 0.037
cytokine production GO:0001816 319 0.037
regulation of neurotransmitter levels GO:0001505 87 0.037
angiogenesis GO:0001525 201 0.037
response to radiation GO:0009314 165 0.037
response to growth factor GO:0070848 198 0.037
regulation of leukocyte apoptotic process GO:2000106 56 0.036
sequestering of calcium ion GO:0051208 18 0.036
membrane tubulation GO:0097320 4 0.036
response to organic cyclic compound GO:0014070 198 0.036
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.036
sensory perception of mechanical stimulus GO:0050954 107 0.035
positive regulation of gtpase activity GO:0043547 85 0.035
positive regulation of kinase activity GO:0033674 155 0.035
ribonucleoprotein complex subunit organization GO:0071826 28 0.035
nucleoside metabolic process GO:0009116 246 0.035
regulation of neuron death GO:1901214 134 0.035
regulation of membrane potential GO:0042391 192 0.035
axon guidance GO:0007411 141 0.035
regulation of ras protein signal transduction GO:0046578 114 0.034
cell substrate adhesion GO:0031589 130 0.034
l alpha amino acid transmembrane transport GO:1902475 23 0.034
regulation of system process GO:0044057 200 0.034
negative regulation of protein phosphorylation GO:0001933 126 0.034
learning or memory GO:0007611 148 0.034
protein processing GO:0016485 163 0.033
intrinsic apoptotic signaling pathway GO:0097193 132 0.033
gliogenesis GO:0042063 141 0.033
actin polymerization or depolymerization GO:0008154 54 0.033
leukocyte migration GO:0050900 124 0.033
adaptive immune response GO:0002250 155 0.033
glutamate receptor signaling pathway GO:0007215 35 0.033
neurotransmitter transport GO:0006836 76 0.032
ion transmembrane transport GO:0034220 361 0.032
divalent metal ion transport GO:0070838 172 0.032
endomembrane system organization GO:0010256 147 0.032
branchiomotor neuron axon guidance GO:0021785 7 0.032
leukocyte proliferation GO:0070661 172 0.032
cellular response to growth factor stimulus GO:0071363 197 0.032
associative learning GO:0008306 61 0.032
regulation of mapk cascade GO:0043408 248 0.032
regulation of protein transport GO:0051223 163 0.032
cellular chemical homeostasis GO:0055082 215 0.031
homeostasis of number of cells GO:0048872 210 0.031
ribonucleotide catabolic process GO:0009261 208 0.031
axonogenesis GO:0007409 274 0.031
motor neuron axon guidance GO:0008045 26 0.031
small gtpase mediated signal transduction GO:0007264 97 0.031
l lysine transport GO:1902022 2 0.031
membrane organization GO:0061024 245 0.031
purine ribonucleotide metabolic process GO:0009150 290 0.031
cellular ketone metabolic process GO:0042180 84 0.031
gtp catabolic process GO:0006184 143 0.030
anatomical structure homeostasis GO:0060249 145 0.030
regulation of cell cycle GO:0051726 281 0.030
reactive oxygen species metabolic process GO:0072593 84 0.030
negative regulation of intracellular signal transduction GO:1902532 167 0.030
positive regulation of protein kinase activity GO:0045860 144 0.029
regulation of exocytosis GO:0017157 61 0.029
dna metabolic process GO:0006259 303 0.029
cilium assembly GO:0042384 81 0.029
positive regulation of apoptotic process GO:0043065 217 0.029
granulocyte migration GO:0097530 43 0.029
aromatic compound catabolic process GO:0019439 286 0.029
regulation of neuron apoptotic process GO:0043523 122 0.029
single organism cell adhesion GO:0098602 156 0.029
response to organonitrogen compound GO:0010243 246 0.029
positive regulation of protein modification process GO:0031401 299 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
regulation of b cell activation GO:0050864 81 0.029
regulation of lymphocyte apoptotic process GO:0070228 41 0.029
meiotic cell cycle GO:0051321 122 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
negative regulation of synaptic transmission glutamatergic GO:0051967 4 0.028
divalent inorganic cation homeostasis GO:0072507 138 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
regulation of organelle organization GO:0033043 289 0.028
purine nucleoside triphosphate catabolic process GO:0009146 203 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.028
positive regulation of protein transport GO:0051222 93 0.027
oocyte anterior posterior axis specification GO:0007314 2 0.027
guanosine containing compound metabolic process GO:1901068 144 0.027
developmental maturation GO:0021700 193 0.027
Fly
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.027
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.027
regulation of protein serine threonine kinase activity GO:0071900 157 0.027
nucleocytoplasmic transport GO:0006913 139 0.027
response to monosaccharide GO:0034284 67 0.027
carbohydrate homeostasis GO:0033500 128 0.027
cellular polysaccharide metabolic process GO:0044264 38 0.026
regulation of apoptotic signaling pathway GO:2001233 197 0.026
cell maturation GO:0048469 127 0.026
Fly
purine containing compound catabolic process GO:0072523 213 0.026
regulation of cytokine production GO:0001817 266 0.026
action potential GO:0001508 78 0.026
epithelial cell development GO:0002064 159 0.026
lymphocyte apoptotic process GO:0070227 54 0.026
synaptic transmission cholinergic GO:0007271 7 0.026
meiotic cytokinesis GO:0033206 5 0.025
protein autophosphorylation GO:0046777 61 0.025
renal tubule development GO:0061326 87 0.025
erk1 and erk2 cascade GO:0070371 77 0.025
negative regulation of molecular function GO:0044092 258 0.025
rho protein signal transduction GO:0007266 32 0.025
oxidation reduction process GO:0055114 342 0.025
positive regulation of organelle organization GO:0010638 128 0.025
neuron neuron synaptic transmission GO:0007270 69 0.025
rna processing GO:0006396 105 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
positive regulation of cytokine production GO:0001819 174 0.025
neuronal action potential GO:0019228 54 0.024
visual learning GO:0008542 44 0.024
branching morphogenesis of an epithelial tube GO:0048754 159 0.024
muscle cell development GO:0055001 133 0.024
glucose homeostasis GO:0042593 128 0.024
acetylcholine transport GO:0015870 2 0.024
body morphogenesis GO:0010171 45 0.024
sequestering of metal ion GO:0051238 19 0.024
purine containing compound metabolic process GO:0072521 311 0.024
leukocyte differentiation GO:0002521 342 0.024
microtubule sliding GO:0051012 1 0.024
intracellular mrna localization GO:0008298 4 0.024
peptidyl tyrosine phosphorylation GO:0018108 143 0.024
protein maturation GO:0051604 176 0.024
striated muscle cell development GO:0055002 125 0.023
cellular response to dna damage stimulus GO:0006974 207 0.023
myeloid leukocyte migration GO:0097529 57 0.023
muscle fiber development GO:0048747 76 0.023
nucleoside phosphate catabolic process GO:1901292 222 0.023
positive regulation of cell development GO:0010720 237 0.023
positive regulation of intracellular transport GO:0032388 70 0.023
sensory perception of sound GO:0007605 97 0.023
muscle tissue development GO:0060537 308 0.023
conditioned taste aversion GO:0001661 4 0.023
cellular macromolecule catabolic process GO:0044265 206 0.022
t cell proliferation GO:0042098 120 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
regulation of purine nucleotide catabolic process GO:0033121 122 0.022
oocyte differentiation GO:0009994 35 0.022
Fly
potassium ion homeostasis GO:0055075 4 0.022
erythrocyte differentiation GO:0030218 88 0.022
ribose phosphate metabolic process GO:0019693 291 0.022
positive regulation of synaptic transmission gabaergic GO:0032230 8 0.022
neuron death GO:0070997 154 0.022
synapse organization GO:0050808 125 0.022
positive regulation of t cell activation GO:0050870 101 0.022
negative regulation of cell size GO:0045792 3 0.022
positive regulation of lymphocyte activation GO:0051251 140 0.022
telencephalon development GO:0021537 186 0.022
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.022
kidney epithelium development GO:0072073 121 0.022
nucleotide catabolic process GO:0009166 217 0.022
response to oxygen levels GO:0070482 62 0.022
positive regulation of cellular catabolic process GO:0031331 148 0.021
visual behavior GO:0007632 45 0.021
regulation of cysteine type endopeptidase activity GO:2000116 65 0.021
regulation of postsynaptic membrane potential GO:0060078 48 0.021
peptidyl amino acid modification GO:0018193 336 0.021
myotube cell development GO:0014904 60 0.021
energy reserve metabolic process GO:0006112 39 0.021
divalent inorganic cation transport GO:0072511 178 0.021
regulation of embryonic development GO:0045995 71 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
monosaccharide metabolic process GO:0005996 106 0.021
maternal determination of anterior posterior axis embryo GO:0008358 2 0.021
tissue homeostasis GO:0001894 115 0.021
positive regulation of cell adhesion GO:0045785 80 0.021
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.021
regulation of nucleoside metabolic process GO:0009118 130 0.021
regulation of blood circulation GO:1903522 93 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
photoreceptor cell development GO:0042461 40 0.020
l amino acid transport GO:0015807 32 0.020
positive regulation of eosinophil migration GO:2000418 2 0.020
nephron tubule development GO:0072080 84 0.020
regulation of actin polymerization or depolymerization GO:0008064 45 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
cellular response to lipid GO:0071396 145 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
mitochondrion organization GO:0007005 134 0.020
Fly
epithelial tube formation GO:0072175 130 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
positive regulation of gtp catabolic process GO:0033126 85 0.020
leukocyte chemotaxis GO:0030595 69 0.020
nucleobase containing compound transport GO:0015931 27 0.020
mrna metabolic process GO:0016071 84 0.020
thymocyte migration GO:0072679 2 0.019
regulation of calcium ion transport GO:0051924 69 0.019
b cell apoptotic process GO:0001783 19 0.019
peptide transport GO:0015833 133 0.019
hormone secretion GO:0046879 128 0.019
negative regulation of transferase activity GO:0051348 85 0.019
regulation of protein catabolic process GO:0042176 108 0.019
meiotic cell cycle process GO:1903046 77 0.019
molting cycle GO:0042303 90 0.019
b cell proliferation GO:0042100 53 0.019
positive regulation of proteolysis GO:0045862 85 0.019
centrosome separation GO:0051299 4 0.019
regulation of gtp catabolic process GO:0033124 113 0.019
lymphocyte homeostasis GO:0002260 64 0.019
cognition GO:0050890 149 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.019
regulation of endocytosis GO:0030100 69 0.019
camera type eye development GO:0043010 266 0.019
regulation of actin cytoskeleton organization GO:0032956 84 0.019
negative regulation of neuron apoptotic process GO:0043524 92 0.019
response to nutrient levels GO:0031667 109 0.019
regulation of map kinase activity GO:0043405 120 0.019
macromolecular complex disassembly GO:0032984 43 0.019
metal ion homeostasis GO:0055065 189 0.018
positive regulation of cell motility GO:2000147 116 0.018
oocyte development GO:0048599 33 0.018
Fly
glycoprotein metabolic process GO:0009100 116 0.018
regulation of stress activated mapk cascade GO:0032872 69 0.018
positive regulation of gene silencing by mirna GO:2000637 1 0.018
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.018
renal system development GO:0072001 225 0.018
aminoglycan metabolic process GO:0006022 34 0.018
response to hypoxia GO:0001666 58 0.018
detection of mechanical stimulus involved in sensory perception GO:0050974 23 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
response to temperature stimulus GO:0009266 55 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
cell junction assembly GO:0034329 52 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
morphogenesis of a branching structure GO:0001763 203 0.017
regulation of nucleocytoplasmic transport GO:0046822 73 0.017
oogenesis GO:0048477 56 0.017
Fly
t cell differentiation GO:0030217 174 0.017
morphogenesis of a polarized epithelium GO:0001738 37 0.017
neurotransmitter secretion GO:0007269 62 0.017
modification dependent protein catabolic process GO:0019941 133 0.017
detection of stimulus GO:0051606 84 0.017
cellular glucan metabolic process GO:0006073 32 0.017
mitotic cell cycle GO:0000278 195 0.017
cellular protein catabolic process GO:0044257 155 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
cellular response to glucose stimulus GO:0071333 45 0.017
rac protein signal transduction GO:0016601 13 0.017
rna splicing GO:0008380 54 0.017
response to transforming growth factor beta GO:0071559 88 0.017
cellularization GO:0007349 1 0.017
gene silencing GO:0016458 38 0.017
response to drug GO:0042493 75 0.017
wnt signaling pathway GO:0016055 188 0.016
keratinocyte differentiation GO:0030216 48 0.016
stress granule disassembly GO:0035617 2 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
regulation of intracellular protein transport GO:0033157 82 0.016
gene silencing by mirna GO:0035195 10 0.016
negative regulation of lymphocyte activation GO:0051250 91 0.016
membrane hyperpolarization GO:0060081 21 0.016
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.016
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.016
amino acid transport GO:0006865 61 0.016
sperm motility GO:0030317 47 0.016
cytokinetic process GO:0032506 2 0.016
t cell differentiation in thymus GO:0033077 77 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.016
dephosphorylation GO:0016311 129 0.016
positive regulation of immune effector process GO:0002699 107 0.015
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.015
regulation of mrna metabolic process GO:1903311 43 0.015
positive regulation of transferase activity GO:0051347 167 0.015
female gamete generation GO:0007292 74 0.015
Fly
gene silencing by rna GO:0031047 19 0.015
cytosolic calcium ion homeostasis GO:0051480 70 0.015
glial cell differentiation GO:0010001 131 0.015
acetylcholine secretion neurotransmission GO:0014055 2 0.015
neutrophil migration GO:1990266 37 0.015
regulation of t cell proliferation GO:0042129 92 0.015
neural tube formation GO:0001841 108 0.015
regulation of phosphate transport GO:0010966 1 0.015
respiratory system development GO:0060541 190 0.015
negative regulation of homeostatic process GO:0032845 71 0.015
response to alcohol GO:0097305 48 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.015
neutrophil chemotaxis GO:0030593 36 0.015
glucan metabolic process GO:0044042 32 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
nephron development GO:0072006 109 0.014
establishment of glial blood brain barrier GO:0060857 2 0.014
response to alkaloid GO:0043279 34 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
peptide secretion GO:0002790 114 0.014
establishment of rna localization GO:0051236 18 0.014
regulated secretory pathway GO:0045055 32 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
regulation of dopamine secretion GO:0014059 9 0.014
gland development GO:0048732 330 0.014
regulation of carbohydrate metabolic process GO:0006109 75 0.014
amino acid transmembrane transport GO:0003333 37 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
positive regulation of vesicle fusion GO:0031340 2 0.014
negative regulation of immune system process GO:0002683 209 0.014
neural precursor cell proliferation GO:0061351 121 0.014
protein localization to nucleus GO:0034504 121 0.014
negative regulation of mapk cascade GO:0043409 65 0.014
protein targeting GO:0006605 143 0.014
nephron epithelium development GO:0072009 92 0.014
positive regulation of ion transport GO:0043270 65 0.014
positive regulation of receptor internalization GO:0002092 4 0.014
positive regulation of map kinase activity GO:0043406 84 0.014
regulation of circadian sleep wake cycle GO:0042749 3 0.014
wound healing GO:0042060 157 0.014
dopamine secretion GO:0014046 9 0.014
ameboidal type cell migration GO:0001667 128 0.013
negative regulation of growth GO:0045926 99 0.013
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.013
striated muscle tissue development GO:0014706 293 0.013
regulation of synaptic transmission glutamatergic GO:0051966 19 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.013
immune effector process GO:0002252 321 0.013
positive regulation of exocytosis GO:0045921 20 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013

Hap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.067
disease of anatomical entity DOID:7 0 0.067
nervous system disease DOID:863 0 0.067
paraplegia DOID:607 0 0.013
hereditary spastic paraplegia DOID:2476 0 0.013