Mus musculus

0 known processes

Hccs

holocytochrome c synthetase

Hccs biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of ripoptosome assembly involved in necroptotic process GO:1902443 3 0.759
mitochondrion organization GO:0007005 134 0.424
regulation of mitochondrial fission GO:0090140 3 0.378
necroptotic process GO:0070266 21 0.351
endoplasmic reticulum tubular network organization GO:0071786 1 0.283
negative regulation of cellular component organization GO:0051129 194 0.262
ripoptosome assembly involved in necroptotic process GO:1901026 6 0.230
macromolecule catabolic process GO:0009057 281 0.205
negative regulation of protein maturation GO:1903318 79 0.201
negative regulation of necroptotic process GO:0060546 9 0.197
regulation of protein complex assembly GO:0043254 83 0.157
necrotic cell death GO:0070265 30 0.141
nitrogen compound transport GO:0071705 271 0.138
protein polyubiquitination GO:0000209 33 0.134
nucleoside phosphate metabolic process GO:0006753 338 0.131
regulation of necrotic cell death GO:0010939 13 0.125
organonitrogen compound biosynthetic process GO:1901566 192 0.120
regulation of protein maturation GO:1903317 96 0.120
protein processing GO:0016485 163 0.117
programmed necrotic cell death GO:0097300 28 0.115
regulation of mitochondrion organization GO:0010821 27 0.112
regulation of cellular component biogenesis GO:0044087 181 0.112
cellular amino acid metabolic process GO:0006520 103 0.111
regulation of cellular catabolic process GO:0031329 242 0.110
negative regulation of protein metabolic process GO:0051248 282 0.109
mitochondrion distribution GO:0048311 4 0.103
c4 dicarboxylate transport GO:0015740 3 0.102
regulation of proteolysis GO:0030162 164 0.102
protein maturation GO:0051604 176 0.099
regulation of membrane potential GO:0042391 192 0.097
negative regulation of cellular protein metabolic process GO:0032269 247 0.092
detection of bacterium GO:0016045 7 0.087
regulation of reactive oxygen species metabolic process GO:2000377 40 0.085
nucleotide metabolic process GO:0009117 332 0.084
pyroptosis GO:0070269 8 0.083
synaptic transmission GO:0007268 329 0.082
pyridine nucleotide biosynthetic process GO:0019363 4 0.078
glutamate biosynthetic process GO:0006537 2 0.077
multicellular organismal macromolecule catabolic process GO:0044266 1 0.076
negative regulation of protein processing GO:0010955 79 0.075
cation transport GO:0006812 399 0.074
nucleobase containing small molecule metabolic process GO:0055086 352 0.072
negative regulation of proteolysis GO:0045861 74 0.071
detection of biotic stimulus GO:0009595 10 0.070
alpha amino acid metabolic process GO:1901605 59 0.067
ion transmembrane transport GO:0034220 361 0.067
placenta development GO:0001890 140 0.064
regulation of ripoptosome assembly involved in necroptotic process GO:1902442 3 0.064
regulation of endopeptidase activity GO:0052548 89 0.062
glutamine family amino acid biosynthetic process GO:0009084 2 0.060
cellular response to dna damage stimulus GO:0006974 207 0.060
intracellular protein transport GO:0006886 204 0.057
heterocycle catabolic process GO:0046700 280 0.056
centrosome separation GO:0051299 4 0.054
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.054
negative regulation of protein complex assembly GO:0031333 25 0.053
transmembrane transport GO:0055085 412 0.052
negative regulation of endopeptidase activity GO:0010951 44 0.051
reactive oxygen species metabolic process GO:0072593 84 0.051
response to organic cyclic compound GO:0014070 198 0.051
cellular response to hormone stimulus GO:0032870 150 0.050
negative regulation of phosphate metabolic process GO:0045936 184 0.050
neuron apoptotic process GO:0051402 142 0.050
negative regulation of peptidase activity GO:0010466 46 0.049
aromatic compound catabolic process GO:0019439 286 0.049
rhythmic process GO:0048511 174 0.049
defense response to bacterium GO:0042742 119 0.048
muscle cell differentiation GO:0042692 261 0.047
negative regulation of hydrolase activity GO:0051346 71 0.047
oxidation reduction process GO:0055114 342 0.047
meiotic cell cycle process GO:1903046 77 0.046
telencephalon development GO:0021537 186 0.044
neuron death GO:0070997 154 0.044
inflammatory response GO:0006954 244 0.043
engulfment of apoptotic cell GO:0043652 3 0.043
cellular amine metabolic process GO:0044106 44 0.042
regulation of cysteine type endopeptidase activity GO:2000116 65 0.041
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.041
canonical wnt signaling pathway GO:0060070 130 0.040
protein modification by small protein conjugation or removal GO:0070647 207 0.040
negative regulation of necrotic cell death GO:0060547 11 0.040
alpha amino acid biosynthetic process GO:1901607 15 0.040
regulation of cell cycle process GO:0010564 160 0.040
regulation of organelle organization GO:0033043 289 0.040
regulation of establishment of protein localization GO:0070201 181 0.040
wnt signaling pathway GO:0016055 188 0.039
cellular response to organic cyclic compound GO:0071407 87 0.039
positive regulation of wnt signaling pathway GO:0030177 45 0.039
l amino acid transport GO:0015807 32 0.039
detection of stimulus GO:0051606 84 0.039
regulation of protein catabolic process GO:0042176 108 0.038
small molecule biosynthetic process GO:0044283 132 0.038
regulation of peptidase activity GO:0052547 96 0.038
cation transmembrane transport GO:0098655 266 0.037
regulation of protein transport GO:0051223 163 0.036
negative regulation of phosphorus metabolic process GO:0010563 184 0.036
dna metabolic process GO:0006259 303 0.035
protein localization to organelle GO:0033365 185 0.034
dendrite development GO:0016358 115 0.034
multicellular organismal protein metabolic process GO:0044268 2 0.034
detection of other organism GO:0098543 8 0.034
amine metabolic process GO:0009308 45 0.034
inhibition of cysteine type endopeptidase activity involved in apoptotic process GO:1990001 1 0.034
protein catabolic process GO:0030163 221 0.033
response to estrogen GO:0043627 24 0.033
organelle assembly GO:0070925 177 0.033
cellular response to lipid GO:0071396 145 0.033
negative regulation of neuron apoptotic process GO:0043524 92 0.033
ribonucleoprotein complex disassembly GO:0032988 3 0.033
metaphase plate congression GO:0051310 2 0.033
positive regulation of protein transport GO:0051222 93 0.032
response to steroid hormone GO:0048545 56 0.032
ribonucleoside catabolic process GO:0042454 206 0.032
mitotic cell cycle GO:0000278 195 0.031
endocytosis GO:0006897 168 0.031
Worm
circulatory system process GO:0003013 197 0.030
intracellular distribution of mitochondria GO:0048312 1 0.030
regulation of canonical wnt signaling pathway GO:0060828 82 0.030
cellular nitrogen compound catabolic process GO:0044270 280 0.030
protein modification by small protein conjugation GO:0032446 187 0.030
multicellular organismal homeostasis GO:0048871 164 0.030
membrane organization GO:0061024 245 0.030
glutamate metabolic process GO:0006536 9 0.030
response to organonitrogen compound GO:0010243 246 0.029
regulation of protein localization GO:0032880 231 0.029
organophosphate catabolic process GO:0046434 232 0.029
cellular protein complex assembly GO:0043623 116 0.029
lateral inhibition GO:0046331 1 0.029
organic acid biosynthetic process GO:0016053 86 0.029
organic cyclic compound catabolic process GO:1901361 295 0.029
negative regulation of phosphorylation GO:0042326 166 0.029
protein secretion GO:0009306 111 0.029
cellular response to steroid hormone stimulus GO:0071383 33 0.028
dephosphorylation GO:0016311 129 0.028
multi multicellular organism process GO:0044706 109 0.027
nucleoside metabolic process GO:0009116 246 0.027
germ cell development GO:0007281 185 0.027
negative regulation of cysteine type endopeptidase activity GO:2000117 22 0.026
cellular homeostasis GO:0019725 240 0.026
negative regulation of reactive oxygen species metabolic process GO:2000378 10 0.026
positive regulation of protein modification process GO:0031401 299 0.026
inorganic ion transmembrane transport GO:0098660 234 0.026
dicarboxylic acid metabolic process GO:0043648 18 0.025
regulation of necroptotic process GO:0060544 10 0.025
endomembrane system organization GO:0010256 147 0.025
spermatid differentiation GO:0048515 115 0.025
detection of external biotic stimulus GO:0098581 9 0.025
negative regulation of organelle organization GO:0010639 90 0.025
mitotic cytokinesis GO:0000281 4 0.024
homeostasis of number of cells GO:0048872 210 0.024
ras protein signal transduction GO:0007265 77 0.024
purine ribonucleoside metabolic process GO:0046128 241 0.023
regulation of cell cycle phase transition GO:1901987 77 0.023
oocyte axis specification GO:0007309 2 0.023
multicellular organismal protein catabolic process GO:0044254 1 0.022
digestive tract development GO:0048565 190 0.022
defense response to other organism GO:0098542 197 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
regulation of cell cycle GO:0051726 281 0.022
ribonucleotide metabolic process GO:0009259 291 0.021
cellular response to growth factor stimulus GO:0071363 197 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
golgi vesicle transport GO:0048193 30 0.021
establishment of protein localization to organelle GO:0072594 118 0.021
negative regulation of molecular function GO:0044092 258 0.021
mitochondrion transport along microtubule GO:0047497 3 0.021
amino acid transport GO:0006865 61 0.021
nicotinamide nucleotide biosynthetic process GO:0019359 4 0.021
muscle tissue development GO:0060537 308 0.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.020
d amino acid transport GO:0042940 1 0.020
positive regulation of proteolysis GO:0045862 85 0.020
nuclear transport GO:0051169 139 0.020
regulation of neuron differentiation GO:0045664 281 0.020
spermatid development GO:0007286 108 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
organelle disassembly GO:1903008 2 0.020
response to acid chemical GO:0001101 111 0.020
regulation of intracellular transport GO:0032386 159 0.020
inhibition of cysteine type endopeptidase activity GO:0097340 1 0.020
positive regulation of peptidase activity GO:0010952 49 0.019
positive regulation of protein ubiquitination GO:0031398 27 0.019
regulation of secretion by cell GO:1903530 249 0.019
carboxylic acid biosynthetic process GO:0046394 86 0.019
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.019
monocarboxylic acid metabolic process GO:0032787 191 0.019
cytoplasmic transport GO:0016482 234 0.019
ribonucleoside monophosphate metabolic process GO:0009161 80 0.019
chromatin organization GO:0006325 206 0.019
cellular metal ion homeostasis GO:0006875 151 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.018
zymogen inhibition GO:0097341 1 0.018
intracellular mrna localization GO:0008298 4 0.018
response to oxidative stress GO:0006979 123 0.018
establishment of vesicle localization GO:0051650 81 0.018
locomotory behavior GO:0007626 195 0.018
organelle fission GO:0048285 170 0.018
digestive tract morphogenesis GO:0048546 147 0.018
cellular lipid metabolic process GO:0044255 323 0.018
regulation of translation GO:0006417 71 0.018
organelle localization GO:0051640 179 0.018
rho protein signal transduction GO:0007266 32 0.018
inorganic cation transmembrane transport GO:0098662 207 0.017
response to radiation GO:0009314 165 0.017
regulation of protein ubiquitination GO:0031396 52 0.017
cell cycle checkpoint GO:0000075 47 0.017
positive regulation of mitochondrial fission GO:0090141 2 0.017
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.017
meiosis i GO:0007127 60 0.017
oocyte anterior posterior axis specification GO:0007314 2 0.017
protein oligomerization GO:0051259 67 0.017
multi organism behavior GO:0051705 62 0.017
regulation of neuron apoptotic process GO:0043523 122 0.017
protein localization to mitochondrion GO:0070585 15 0.017
glutamine family amino acid metabolic process GO:0009064 15 0.017
muscle cell development GO:0055001 133 0.017
circadian rhythm GO:0007623 114 0.016
positive regulation of cell death GO:0010942 224 0.016
mitochondrial transport GO:0006839 36 0.016
neuromuscular process GO:0050905 99 0.016
rna interference GO:0016246 2 0.016
response to light stimulus GO:0009416 135 0.016
bone development GO:0060348 120 0.016
protein targeting to mitochondrion GO:0006626 6 0.016
vesicle localization GO:0051648 86 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
carbohydrate transport GO:0008643 62 0.016
nuclear division GO:0000280 158 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.016
cell type specific apoptotic process GO:0097285 268 0.016
translation GO:0006412 93 0.016
response to inorganic substance GO:0010035 96 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.015
maternal process involved in female pregnancy GO:0060135 32 0.015
anion transport GO:0006820 177 0.015
monocarboxylic acid biosynthetic process GO:0072330 61 0.015
learning or memory GO:0007611 148 0.015
nucleobase containing compound transport GO:0015931 27 0.015
gtp metabolic process GO:0046039 144 0.015
organic acid transport GO:0015849 101 0.015
striated muscle tissue development GO:0014706 293 0.015
dna integrity checkpoint GO:0031570 28 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
sensory perception GO:0007600 245 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.015
positive regulation of protein secretion GO:0050714 52 0.015
regulation of hydrolase activity GO:0051336 246 0.015
response to reactive oxygen species GO:0000302 56 0.015
regulation of mitotic cell cycle phase transition GO:1901990 73 0.015
purine ribonucleotide catabolic process GO:0009154 208 0.015
protein targeting GO:0006605 143 0.015
aspartate transport GO:0015810 2 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
response to amino acid GO:0043200 37 0.015
adult locomotory behavior GO:0008344 91 0.014
pole plasm assembly GO:0007315 2 0.014
cation homeostasis GO:0055080 212 0.014
heart process GO:0003015 94 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
regulation of secretion GO:0051046 274 0.014
spermatogenesis GO:0007283 284 0.014
coenzyme metabolic process GO:0006732 52 0.014
cellular chemical homeostasis GO:0055082 215 0.014
purine containing compound metabolic process GO:0072521 311 0.014
sodium ion transport GO:0006814 73 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
establishment of rna localization GO:0051236 18 0.013
vesicle organization GO:0016050 60 0.013
cell adhesion GO:0007155 329 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
pallium development GO:0021543 120 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
amide transport GO:0042886 138 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
ripoptosome assembly GO:0097343 6 0.013
striated muscle cell development GO:0055002 125 0.013
trophectodermal cellular morphogenesis GO:0001831 3 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
regulation of cell division GO:0051302 76 0.013
glycoprotein metabolic process GO:0009100 116 0.013
chromosome organization involved in meiosis GO:0070192 39 0.013
blood circulation GO:0008015 195 0.013
dicarboxylic acid biosynthetic process GO:0043650 5 0.013
regulation of protein secretion GO:0050708 82 0.013
mitochondrion degradation GO:0000422 3 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
positive regulation of cell cycle GO:0045787 92 0.012
organic anion transport GO:0015711 137 0.012
regulation of protein processing GO:0070613 96 0.012
l alpha amino acid transmembrane transport GO:1902475 23 0.012
glucose homeostasis GO:0042593 128 0.012
endoplasmic reticulum organization GO:0007029 10 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
plasma membrane organization GO:0007009 90 0.012
establishment of organelle localization GO:0051656 122 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
amino acid transmembrane transport GO:0003333 37 0.012
multi organism reproductive behavior GO:0044705 29 0.012
rna localization GO:0006403 23 0.012
positive regulation of mitotic metaphase anaphase transition GO:0045842 2 0.012
oxidoreduction coenzyme metabolic process GO:0006733 16 0.012
compound eye development GO:0048749 1 0.012
response to growth factor GO:0070848 198 0.012
regulation of protein targeting GO:1903533 61 0.012
skeletal muscle organ development GO:0060538 163 0.012
l glutamate transport GO:0015813 16 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
cellular ion homeostasis GO:0006873 165 0.012
transmission of nerve impulse GO:0019226 76 0.012
chromatin modification GO:0016568 187 0.011
response to transforming growth factor beta GO:0071559 88 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
gonad development GO:0008406 141 0.011
male gamete generation GO:0048232 285 0.011
defecation GO:0030421 1 0.011
carboxylic acid transport GO:0046942 100 0.011
carbohydrate metabolic process GO:0005975 230 0.011
cellular response to arsenic containing substance GO:0071243 4 0.011
ribonucleoprotein complex subunit organization GO:0071826 28 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
meiotic nuclear division GO:0007126 115 0.011
meiotic cell cycle GO:0051321 122 0.011
polyamine biosynthetic process GO:0006596 2 0.011
protein localization to membrane GO:0072657 108 0.011
positive regulation of chromosome segregation GO:0051984 4 0.011
gland development GO:0048732 330 0.011
neuromuscular process controlling balance GO:0050885 59 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
negative regulation of cell cycle GO:0045786 123 0.011
protein localization to nucleus GO:0034504 121 0.011
multicellular organismal catabolic process GO:0044243 7 0.011
response to extracellular stimulus GO:0009991 127 0.011
anatomical structure homeostasis GO:0060249 145 0.011
positive regulation of cell development GO:0010720 237 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
adult behavior GO:0030534 135 0.011
cardiac muscle tissue development GO:0048738 130 0.011
regulation of protein oligomerization GO:0032459 4 0.011
nucleotide catabolic process GO:0009166 217 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
stress activated mapk cascade GO:0051403 80 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
modification dependent protein catabolic process GO:0019941 133 0.010
copii coated vesicle budding GO:0090114 2 0.010
response to alcohol GO:0097305 48 0.010
negative regulation of mitotic cell cycle GO:0045930 58 0.010
cell maturation GO:0048469 127 0.010
purine nucleotide metabolic process GO:0006163 302 0.010
protein homooligomerization GO:0051260 43 0.010
nucleoside catabolic process GO:0009164 206 0.010
positive regulation of apoptotic process GO:0043065 217 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
localization within membrane GO:0051668 4 0.010
cellular component assembly involved in morphogenesis GO:0010927 139 0.010
lipid biosynthetic process GO:0008610 179 0.010
positive regulation of secretion by cell GO:1903532 114 0.010
metal ion homeostasis GO:0055065 189 0.010
carbohydrate homeostasis GO:0033500 128 0.010
glycosyl compound metabolic process GO:1901657 246 0.010
establishment of melanosome localization GO:0032401 11 0.010
phosphatidylethanolamine metabolic process GO:0046337 2 0.010
neuron neuron synaptic transmission GO:0007270 69 0.010
synapsis GO:0007129 34 0.010

Hccs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
disease of metabolism DOID:0014667 0 0.025
inherited metabolic disorder DOID:655 0 0.025
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
central nervous system disease DOID:331 0 0.011
neurodegenerative disease DOID:1289 0 0.011
amino acid metabolic disorder DOID:9252 0 0.010