|
|
protein deacetylation
|
GO:0006476 |
32 |
0.998
|
|
|
|
gene silencing by rna
|
GO:0031047 |
19 |
0.995
|
Worm |
|
|
histone modification
|
GO:0016570 |
159 |
0.991
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
37 |
0.986
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.986
|
|
|
|
chromatin silencing
|
GO:0006342 |
15 |
0.983
|
Fly |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.981
|
Worm |
|
|
histone h4 deacetylation
|
GO:0070933 |
4 |
0.978
|
|
|
|
chromatin silencing at rdna
|
GO:0000183 |
3 |
0.970
|
|
|
|
histone deacetylation
|
GO:0016575 |
26 |
0.964
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.963
|
|
|
|
dna methylation
|
GO:0006306 |
43 |
0.963
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
15 |
0.960
|
Fly |
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.947
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.946
|
|
|
|
regulation of protein deacetylation
|
GO:0090311 |
17 |
0.946
|
Mouse |
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.944
|
|
|
|
gene silencing
|
GO:0016458 |
38 |
0.942
|
Worm Fly |
|
|
protein deacylation
|
GO:0035601 |
36 |
0.929
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.927
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.926
|
Fly |
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.888
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.879
|
|
|
|
histone methylation
|
GO:0016571 |
71 |
0.876
|
|
|
|
negative regulation of chromatin silencing
|
GO:0031936 |
1 |
0.870
|
|
|
|
dna modification
|
GO:0006304 |
50 |
0.861
|
|
|
|
regulation of chromatin silencing
|
GO:0031935 |
2 |
0.839
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.837
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.821
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.811
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.793
|
Rat |
|
|
regulation of transcription during meiosis
|
GO:0051037 |
1 |
0.782
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.770
|
Mouse Fly |
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.768
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.764
|
|
|
|
rna interference
|
GO:0016246 |
2 |
0.757
|
Worm |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.722
|
Worm |
|
|
response to radiation
|
GO:0009314 |
165 |
0.721
|
Fly |
|
|
epidermis development
|
GO:0008544 |
187 |
0.719
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.708
|
Worm |
|
|
negative regulation of chromosome organization
|
GO:2001251 |
30 |
0.698
|
|
|
|
histone h3 deacetylation
|
GO:0070932 |
8 |
0.691
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.675
|
Rat |
|
|
methylation
|
GO:0032259 |
134 |
0.673
|
|
|
|
double strand break repair
|
GO:0006302 |
48 |
0.671
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.668
|
Worm |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.666
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.654
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.651
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.640
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
10 |
0.637
|
Worm |
|
|
double strand break repair via nonhomologous end joining
|
GO:0006303 |
10 |
0.631
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.614
|
|
|
|
positive regulation of g2 m transition of mitotic cell cycle
|
GO:0010971 |
5 |
0.593
|
|
|
|
exocrine pancreas development
|
GO:0031017 |
7 |
0.589
|
Zebrafish |
|
|
regulation of cell cycle g2 m phase transition
|
GO:1902749 |
10 |
0.584
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.583
|
Zebrafish Fly |
|
|
transdifferentiation
|
GO:0060290 |
1 |
0.572
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.552
|
|
|
|
negative regulation of chromatin modification
|
GO:1903309 |
19 |
0.522
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.519
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.513
|
Mouse |
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.511
|
Zebrafish |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.510
|
Rat |
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.509
|
|
|
|
positive regulation of receptor biosynthetic process
|
GO:0010870 |
1 |
0.499
|
Human |
|
|
gonad development
|
GO:0008406 |
141 |
0.496
|
Worm |
|
|
maintenance of chromatin silencing
|
GO:0006344 |
2 |
0.492
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.491
|
|
|
|
cell fate specification
|
GO:0001708 |
72 |
0.474
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.466
|
Fly |
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.465
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.464
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.453
|
|
|
|
negative regulation of transcription from rna polymerase i promoter
|
GO:0016479 |
2 |
0.446
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.446
|
Fly |
|
|
positive regulation of histone modification
|
GO:0031058 |
28 |
0.437
|
|
|
|
negative regulation of cardiac muscle cell proliferation
|
GO:0060044 |
5 |
0.431
|
Mouse |
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.425
|
Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.422
|
Rat |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.421
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.419
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.419
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.417
|
Zebrafish Worm |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.413
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.412
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.411
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
3 |
0.396
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.389
|
Rat |
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.389
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.388
|
Zebrafish Mouse Rat |
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.384
|
Rat |
|
|
cell cycle arrest
|
GO:0007050 |
37 |
0.382
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.380
|
Zebrafish |
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.376
|
|
|
|
histone h3 k9 methylation
|
GO:0051567 |
17 |
0.375
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.373
|
Fly |
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.373
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.371
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.365
|
Mouse |
|
|
circadian behavior
|
GO:0048512 |
13 |
0.364
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.360
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.360
|
Worm |
|
|
histone h3 k9 dimethylation
|
GO:0036123 |
4 |
0.359
|
|
|
|
dna alkylation
|
GO:0006305 |
43 |
0.357
|
|
|
|
non recombinational repair
|
GO:0000726 |
10 |
0.356
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.346
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.340
|
Fly |
|
|
blastocyst development
|
GO:0001824 |
80 |
0.339
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.332
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.328
|
Worm |
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.326
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.324
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.322
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.313
|
Rat |
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.311
|
|
|
|
negative regulation of circadian rhythm
|
GO:0042754 |
8 |
0.310
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.303
|
Zebrafish |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.294
|
Mouse Fly |
|
|
negative regulation of histone modification
|
GO:0031057 |
18 |
0.290
|
|
|
|
negative regulation of heart growth
|
GO:0061117 |
7 |
0.289
|
Mouse |
|
|
gland development
|
GO:0048732 |
330 |
0.286
|
Zebrafish |
|
|
receptor biosynthetic process
|
GO:0032800 |
3 |
0.286
|
Human |
|
|
histone acetylation
|
GO:0016573 |
41 |
0.277
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.277
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.271
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
34 |
0.266
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.262
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.257
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.257
|
|
|
|
regeneration
|
GO:0031099 |
38 |
0.249
|
Zebrafish |
|
|
nucleosome disassembly
|
GO:0006337 |
1 |
0.249
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.248
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.247
|
Worm |
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.247
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.245
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.244
|
Human |
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.244
|
Worm |
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.240
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
57 |
0.240
|
|
|
|
regulation of histone h3 k9 methylation
|
GO:0051570 |
8 |
0.239
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.237
|
Mouse Fly |
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.237
|
|
|
|
recombinational repair
|
GO:0000725 |
21 |
0.236
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.235
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.235
|
Zebrafish Worm |
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.230
|
Mouse |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.230
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
8 |
0.229
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.228
|
Worm |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.227
|
|
|
|
negative regulation of gene silencing
|
GO:0060969 |
2 |
0.227
|
|
|
|
protein alkylation
|
GO:0008213 |
81 |
0.225
|
|
|
|
posttranscriptional gene silencing
|
GO:0016441 |
10 |
0.224
|
Worm |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.223
|
|
|
|
chromatin remodeling
|
GO:0006338 |
32 |
0.223
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.218
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.217
|
|
|
|
locomotor rhythm
|
GO:0045475 |
8 |
0.212
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.212
|
Worm |
|
|
regulation of receptor biosynthetic process
|
GO:0010869 |
2 |
0.204
|
Human |
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.203
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.202
|
Fly |
|
|
embryonic digestive tract development
|
GO:0048566 |
27 |
0.202
|
Worm |
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
20 |
0.201
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.198
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.195
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.187
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.184
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.183
|
Rat |
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.181
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
23 |
0.181
|
Mouse |
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.179
|
Zebrafish |
|
|
endocytosis
|
GO:0006897 |
168 |
0.178
|
Worm |
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.176
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.176
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.174
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.174
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.174
|
Mouse Fly |
|
|
dna recombination
|
GO:0006310 |
92 |
0.169
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.164
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.164
|
|
|
|
positive regulation of mitotic cell cycle phase transition
|
GO:1901992 |
17 |
0.163
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.161
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.159
|
Fly |
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.159
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.156
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.152
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.151
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.151
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.151
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.148
|
|
|
|
dna conformation change
|
GO:0071103 |
37 |
0.148
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.148
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.148
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.146
|
Mouse |
|
|
wound healing
|
GO:0042060 |
157 |
0.142
|
Zebrafish |
|
|
dna dependent dna replication
|
GO:0006261 |
24 |
0.141
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.139
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.137
|
Mouse Fly |
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.137
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.136
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.135
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.135
|
Rat |
|
|
regulation of histone methylation
|
GO:0031060 |
30 |
0.134
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.134
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.133
|
Rat |
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.132
|
Mouse Fly |
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.131
|
|
|
|
dna replication
|
GO:0006260 |
52 |
0.131
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.130
|
|
|
|
positive regulation of cell cycle phase transition
|
GO:1901989 |
17 |
0.129
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.129
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.126
|
|
|
|
pancreas development
|
GO:0031016 |
57 |
0.125
|
Zebrafish |
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.125
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
28 |
0.124
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.124
|
|
|
|
cardiac right ventricle formation
|
GO:0003219 |
3 |
0.124
|
|
|
|
regulation of dna methylation
|
GO:0044030 |
12 |
0.124
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.123
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.121
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.120
|
Worm |
|
|
regulation of dna dependent dna replication initiation
|
GO:0030174 |
3 |
0.120
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
34 |
0.118
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.118
|
|
|
|
cardiac muscle cell development
|
GO:0055013 |
39 |
0.118
|
Mouse |
|
|
positive regulation of chromosome organization
|
GO:2001252 |
33 |
0.117
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.115
|
|
|
|
regulation of organelle assembly
|
GO:1902115 |
19 |
0.113
|
Mouse |
|
|
organelle fission
|
GO:0048285 |
170 |
0.112
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
17 |
0.112
|
Mouse |
|
|
dna hypermethylation
|
GO:0044026 |
3 |
0.110
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.110
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.110
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.110
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.109
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.109
|
Worm |
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.108
|
|
|
|
cellular respiration
|
GO:0045333 |
38 |
0.107
|
Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.107
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.106
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.106
|
|
|
|
dna dealkylation
|
GO:0035510 |
11 |
0.106
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.105
|
Zebrafish |
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.104
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.103
|
|
|
|
tissue regeneration
|
GO:0042246 |
22 |
0.103
|
Zebrafish |
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
4 |
0.101
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.099
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.099
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.097
|
Mouse |
|
|
peptidyl lysine methylation
|
GO:0018022 |
29 |
0.097
|
|
|
|
eyelid development in camera type eye
|
GO:0061029 |
9 |
0.096
|
|
|
|
megakaryocyte differentiation
|
GO:0030219 |
26 |
0.094
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
35 |
0.094
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.093
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.091
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.091
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.091
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.090
|
|
|
|
chromatin disassembly
|
GO:0031498 |
1 |
0.089
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.088
|
|
|
|
rhythmic behavior
|
GO:0007622 |
15 |
0.087
|
|
|
|
protein localization to chromatin
|
GO:0071168 |
3 |
0.087
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.087
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.087
|
Zebrafish |
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.087
|
Mouse Fly |
|
|
protein acylation
|
GO:0043543 |
64 |
0.085
|
Rat |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.085
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.084
|
Mouse |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.084
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.084
|
Mouse |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.084
|
Fly |
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
17 |
0.084
|
Worm |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.083
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.083
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.082
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
45 |
0.080
|
Rat |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.080
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.079
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.079
|
Rat |
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.078
|
Mouse |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.077
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.076
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.076
|
Rat |
|
|
blastocyst growth
|
GO:0001832 |
23 |
0.076
|
|
|
|
response to heat
|
GO:0009408 |
27 |
0.075
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.075
|
|
|
|
dna catabolic process
|
GO:0006308 |
19 |
0.075
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.074
|
|
|
|
regulation of histone h3 k4 methylation
|
GO:0051569 |
12 |
0.074
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.074
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.074
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.074
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.073
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
20 |
0.073
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.073
|
Rat |
|
|
intrahepatic bile duct development
|
GO:0035622 |
2 |
0.073
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
14 |
0.072
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.071
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.071
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.071
|
Mouse Fly |
|
|
embryonic digit morphogenesis
|
GO:0042733 |
56 |
0.070
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.070
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.069
|
|
|
|
hair follicle placode formation
|
GO:0060789 |
5 |
0.069
|
|
|
|
positive regulation of histone h3 k4 methylation
|
GO:0051571 |
5 |
0.069
|
|
|
|
negative regulation of cardiac muscle tissue development
|
GO:0055026 |
8 |
0.068
|
Mouse |
|
|
base excision repair
|
GO:0006284 |
9 |
0.067
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.067
|
Mouse |
|
|
chromatin assembly
|
GO:0031497 |
13 |
0.067
|
|
|
|
cytokinesis
|
GO:0000910 |
17 |
0.066
|
|
|
|
sarcomere organization
|
GO:0045214 |
24 |
0.066
|
Mouse |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.066
|
Mouse |
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.066
|
Mouse |
|
|
regulation of system process
|
GO:0044057 |
200 |
0.065
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.065
|
Mouse |
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.064
|
Human |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.064
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.064
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.063
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.063
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
35 |
0.063
|
|
|
|
fungiform papilla morphogenesis
|
GO:0061197 |
5 |
0.061
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.061
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.060
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.060
|
Rat |
|
|
cell division
|
GO:0051301 |
120 |
0.060
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.060
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.059
|
Worm |
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.059
|
|
|
|
regulation of dna replication
|
GO:0006275 |
17 |
0.059
|
|
|
|
regulation of g2 m transition of mitotic cell cycle
|
GO:0010389 |
10 |
0.059
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.058
|
|
|
|
regulation of transcription from rna polymerase i promoter
|
GO:0006356 |
6 |
0.058
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.058
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.058
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.058
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.058
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.058
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.057
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.057
|
Human |
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.057
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.057
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.057
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.056
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.056
|
|
|
|
response to gamma radiation
|
GO:0010332 |
22 |
0.056
|
Fly |
|
|
atrial septum primum morphogenesis
|
GO:0003289 |
3 |
0.055
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.055
|
|
|
|
regulation of transcription regulatory region dna binding
|
GO:2000677 |
9 |
0.055
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
80 |
0.054
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.054
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.054
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.053
|
|
|
|
negative regulation of cell morphogenesis involved in differentiation
|
GO:0010771 |
48 |
0.053
|
Fly |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.053
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
24 |
0.053
|
Fly |
|
|
immune effector process
|
GO:0002252 |
321 |
0.053
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.052
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.052
|
Zebrafish |
|
|
reproductive behavior
|
GO:0019098 |
32 |
0.052
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.052
|
|
|
|
organ regeneration
|
GO:0031100 |
2 |
0.051
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.051
|
|
|
|
histone h3 k9 acetylation
|
GO:0043970 |
5 |
0.051
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.051
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.051
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.051
|
Mouse |
|
|
regulation of exit from mitosis
|
GO:0007096 |
1 |
0.051
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
50 |
0.051
|
Mouse Fly |
|
|
response to alcohol
|
GO:0097305 |
48 |
0.050
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.050
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.050
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
59 |
0.050
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.050
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.050
|
|
|
|
striated muscle cell proliferation
|
GO:0014855 |
39 |
0.049
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.047
|
|
|
|
intestinal epithelial structure maintenance
|
GO:0060729 |
4 |
0.047
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
63 |
0.047
|
|
|
|
regulation of heart growth
|
GO:0060420 |
31 |
0.047
|
Mouse |
|
|
negative regulation of muscle tissue development
|
GO:1901862 |
20 |
0.047
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.046
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.046
|
|
|
|
fungiform papilla development
|
GO:0061196 |
6 |
0.046
|
|
|
|
regulation of rna splicing
|
GO:0043484 |
37 |
0.046
|
|
|
|
cellular response to hexose stimulus
|
GO:0071331 |
47 |
0.045
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.045
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.045
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.045
|
|
|
|
mrna splicing via spliceosome
|
GO:0000398 |
43 |
0.045
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
13 |
0.044
|
Fly |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.044
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.044
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.044
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.044
|
Mouse |
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.043
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.043
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.043
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
26 |
0.043
|
Mouse |
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.043
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.042
|
Fly |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.042
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.042
|
Mouse |
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.042
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.042
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.042
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
52 |
0.042
|
|
|
|
regulation of cell cycle checkpoint
|
GO:1901976 |
9 |
0.041
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.041
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.041
|
|
|
|
response to ketone
|
GO:1901654 |
15 |
0.041
|
|
|
|
synapsis
|
GO:0007129 |
34 |
0.040
|
|
|
|
positive regulation of glial cell differentiation
|
GO:0045687 |
21 |
0.040
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.040
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.040
|
Rat |
|
|
bone development
|
GO:0060348 |
120 |
0.039
|
|
|
|
regulation of peptidyl lysine acetylation
|
GO:2000756 |
22 |
0.039
|
Rat |
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
18 |
0.039
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.038
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.038
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.038
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.038
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
9 |
0.038
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.038
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.037
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.037
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.037
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.037
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.037
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
31 |
0.037
|
Mouse |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.037
|
|
|
|
hippocampus development
|
GO:0021766 |
52 |
0.037
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.037
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.036
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.036
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.036
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
49 |
0.036
|
|
|
|
positive regulation of oligodendrocyte differentiation
|
GO:0048714 |
9 |
0.036
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
17 |
0.036
|
|
|
|
regulation of rna stability
|
GO:0043487 |
26 |
0.035
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.035
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.035
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.035
|
|
|
|
multicellular organismal reproductive behavior
|
GO:0033057 |
23 |
0.035
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.035
|
Rat |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.035
|
|
|
|
meiosis i
|
GO:0007127 |
60 |
0.034
|
|
|
|
demethylation
|
GO:0070988 |
23 |
0.034
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.034
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.034
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.034
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.034
|
|
|
|
cellular response to glucose stimulus
|
GO:0071333 |
45 |
0.034
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.034
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.034
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.034
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.033
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.033
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
16 |
0.033
|
Human |
|
|
regulation of cell cycle arrest
|
GO:0071156 |
12 |
0.033
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.033
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.033
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.033
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.033
|
Mouse |
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.033
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.033
|
Mouse |
|
|
male meiosis
|
GO:0007140 |
37 |
0.033
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.033
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.033
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.033
|
|
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.032
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.032
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.032
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.032
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
41 |
0.032
|
|
|
|
peptidyl lysine trimethylation
|
GO:0018023 |
12 |
0.032
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.031
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.031
|
Mouse |
|
|
negative regulation of dna replication
|
GO:0008156 |
4 |
0.031
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.031
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.031
|
|
|
|
dna replication initiation
|
GO:0006270 |
5 |
0.031
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.031
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.031
|
|
|
|
regulation of dna dependent dna replication
|
GO:0090329 |
8 |
0.031
|
|
