Mus musculus

317 known processes

Hdac2

histone deacetylase 2

(Aliases: Yy1bp,D10Wsu179e,YAF1,mRPD3)

Hdac2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin organization GO:0006325 206 0.980
histone h4 deacetylation GO:0070933 4 0.971
posttranscriptional gene silencing by rna GO:0035194 10 0.958
Worm
rna interference GO:0016246 2 0.956
Worm
protein deacetylation GO:0006476 32 0.950
regionalization GO:0003002 337 0.937
Fly
gene silencing GO:0016458 38 0.914
Human Worm Fly
dna metabolic process GO:0006259 303 0.888
Worm
regulation of apoptotic signaling pathway GO:2001233 197 0.870
covalent chromatin modification GO:0016569 163 0.862
energy derivation by oxidation of organic compounds GO:0015980 77 0.859
Fly
dna modification GO:0006304 50 0.853
dendrite development GO:0016358 115 0.830
gene silencing by rna GO:0031047 19 0.822
Worm
chromatin silencing GO:0006342 15 0.791
Human Fly
posttranscriptional gene silencing GO:0016441 10 0.788
Worm
cellular amine metabolic process GO:0044106 44 0.761
regulation of cell cycle GO:0051726 281 0.758
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.757
Fly
posttranscriptional regulation of gene expression GO:0010608 155 0.747
Worm
organelle fission GO:0048285 170 0.739
male gamete generation GO:0048232 285 0.737
gonad development GO:0008406 141 0.730
Worm
peptidyl amino acid modification GO:0018193 336 0.729
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.728
macromolecule deacylation GO:0098732 37 0.713
wnt signaling pathway GO:0016055 188 0.696
nuclear division GO:0000280 158 0.694
histone modification GO:0016570 159 0.687
development of primary sexual characteristics GO:0045137 143 0.651
Worm
apoptotic signaling pathway GO:0097190 306 0.645
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.641
peptidyl lysine modification GO:0018205 77 0.612
amine metabolic process GO:0009308 45 0.597
negative regulation of ras protein signal transduction GO:0046580 18 0.589
Worm
regulation of cellular amine metabolic process GO:0033238 20 0.589
negative regulation of molecular function GO:0044092 258 0.576
Human
internal peptidyl lysine acetylation GO:0018393 42 0.569
endocytosis GO:0006897 168 0.569
Worm
stem cell maintenance GO:0019827 130 0.562
negative regulation of chromatin silencing GO:0031936 1 0.550
hematopoietic progenitor cell differentiation GO:0002244 143 0.547
cellular response to dna damage stimulus GO:0006974 207 0.532
epidermis development GO:0008544 187 0.530
chromatin modification GO:0016568 187 0.527
meiotic nuclear division GO:0007126 115 0.515
hippocampus development GO:0021766 52 0.513
forebrain development GO:0030900 302 0.509
axonogenesis GO:0007409 274 0.504
Fly
germ cell development GO:0007281 185 0.496
camera type eye development GO:0043010 266 0.495
digestive tract development GO:0048565 190 0.486
Worm
stem cell development GO:0048864 219 0.478
limb morphogenesis GO:0035108 149 0.473
regulation of cellular ketone metabolic process GO:0010565 66 0.466
regulation of multi organism process GO:0043900 111 0.457
cellular amino acid metabolic process GO:0006520 103 0.453
cellular ketone metabolic process GO:0042180 84 0.450
protein acylation GO:0043543 64 0.445
negative regulation of growth GO:0045926 99 0.434
histone acetylation GO:0016573 41 0.433
negative regulation of cardiac muscle cell proliferation GO:0060044 5 0.431
rhythmic process GO:0048511 174 0.425
skin development GO:0043588 220 0.420
positive regulation of receptor biosynthetic process GO:0010870 1 0.417
Human
pallium development GO:0021543 120 0.415
negative regulation of gene expression epigenetic GO:0045814 15 0.410
Human Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.403
double strand break repair GO:0006302 48 0.400
viral process GO:0016032 41 0.397
generation of precursor metabolites and energy GO:0006091 103 0.391
Fly
mrna splicing via spliceosome GO:0000398 43 0.390
spermatogenesis GO:0007283 284 0.388
regulation of receptor biosynthetic process GO:0010869 2 0.376
Human
striated muscle cell development GO:0055002 125 0.376
positive regulation of cell development GO:0010720 237 0.372
regulation of neuron apoptotic process GO:0043523 122 0.357
regulation of cellular amino acid metabolic process GO:0006521 5 0.355
embryonic limb morphogenesis GO:0030326 126 0.347
translation GO:0006412 93 0.345
hindbrain development GO:0030902 128 0.341
cell fate commitment GO:0045165 210 0.341
regulation of chromatin silencing GO:0031935 2 0.340
regulation of protein acetylation GO:1901983 22 0.334
intrinsic apoptotic signaling pathway GO:0097193 132 0.322
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.321
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.320
negative regulation of protein modification process GO:0031400 163 0.318
macromolecule methylation GO:0043414 120 0.315
peptidyl lysine acetylation GO:0018394 45 0.306
positive regulation of protein phosphorylation GO:0001934 242 0.299
negative regulation of cellular protein metabolic process GO:0032269 247 0.296
regulation of neuron differentiation GO:0045664 281 0.294
regulation of binding GO:0051098 111 0.288
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.286
regulation of androgen receptor signaling pathway GO:0060765 3 0.286
regulation of neuron projection development GO:0010975 169 0.284
cell division GO:0051301 120 0.281
spermatid differentiation GO:0048515 115 0.280
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.272
embryonic organ morphogenesis GO:0048562 276 0.270
Worm
neuron apoptotic process GO:0051402 142 0.268
fungiform papilla development GO:0061196 6 0.267
interspecies interaction between organisms GO:0044419 83 0.267
regulation of cell projection organization GO:0031344 206 0.263
negative regulation of apoptotic signaling pathway GO:2001234 104 0.259
regulation of cell cycle process GO:0010564 160 0.259
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.258
negative regulation of cardiac muscle tissue development GO:0055026 8 0.257
microtubule cytoskeleton organization GO:0000226 157 0.256
spermatid development GO:0007286 108 0.247
cell growth GO:0016049 130 0.246
stem cell differentiation GO:0048863 268 0.245
cell type specific apoptotic process GO:0097285 268 0.243
meiotic cell cycle GO:0051321 122 0.242
genitalia development GO:0048806 37 0.239
Worm
negative regulation of nervous system development GO:0051961 156 0.234
oxidation reduction process GO:0055114 342 0.228
Fly
positive regulation of nervous system development GO:0051962 221 0.221
response to heat GO:0009408 27 0.218
methylation GO:0032259 134 0.211
regulation of epithelial cell proliferation GO:0050678 141 0.210
receptor mediated endocytosis GO:0006898 51 0.209
Worm
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.209
negative regulation of protein metabolic process GO:0051248 282 0.206
negative regulation of cellular component organization GO:0051129 194 0.205
chromatin silencing at rdna GO:0000183 3 0.205
epithelial cell proliferation GO:0050673 174 0.203
carbohydrate metabolic process GO:0005975 230 0.202
limb development GO:0060173 166 0.202
regulation of canonical wnt signaling pathway GO:0060828 82 0.200
negative regulation of neuron death GO:1901215 98 0.200
positive regulation of protein modification process GO:0031401 299 0.197
negative regulation of cell proliferation GO:0008285 296 0.197
sensory organ morphogenesis GO:0090596 242 0.197
intracellular receptor signaling pathway GO:0030522 74 0.194
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.194
dna conformation change GO:0071103 37 0.192
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.182
ras protein signal transduction GO:0007265 77 0.180
Worm
regulation of histone modification GO:0031056 56 0.176
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.175
appendage development GO:0048736 166 0.174
histone h3 deacetylation GO:0070932 8 0.174
negative regulation of cell projection organization GO:0031345 56 0.173
organelle assembly GO:0070925 177 0.173
peptidyl lysine trimethylation GO:0018023 12 0.170
telencephalon development GO:0021537 186 0.169
negative regulation of synapse assembly GO:0051964 3 0.168
neuron projection guidance GO:0097485 141 0.168
Fly
regulation of peptidyl lysine acetylation GO:2000756 22 0.165
homeostasis of number of cells GO:0048872 210 0.162
microtubule based process GO:0007017 236 0.162
interaction with symbiont GO:0051702 14 0.161
lung development GO:0030324 164 0.161
negative regulation of neuron projection development GO:0010977 50 0.156
mitotic cell cycle GO:0000278 195 0.155
negative regulation of neuron differentiation GO:0045665 101 0.153
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.152
multi multicellular organism process GO:0044706 109 0.146
regulation of cell cycle phase transition GO:1901987 77 0.145
neuron death GO:0070997 154 0.145
cardiac muscle cell differentiation GO:0055007 69 0.144
tissue migration GO:0090130 68 0.144
developmental growth involved in morphogenesis GO:0060560 138 0.144
digestive tract morphogenesis GO:0048546 147 0.142
Worm
regulation of cell growth GO:0001558 91 0.139
negative regulation of neuron apoptotic process GO:0043524 92 0.138
cell fate specification GO:0001708 72 0.136
embryonic digestive tract development GO:0048566 27 0.136
Worm
response to molecule of bacterial origin GO:0002237 143 0.136
nitrogen compound transport GO:0071705 271 0.135
histone deacetylation GO:0016575 26 0.135
liver development GO:0001889 66 0.133
internal protein amino acid acetylation GO:0006475 42 0.132
organic cyclic compound catabolic process GO:1901361 295 0.131
viral life cycle GO:0019058 36 0.130
positive regulation of cell cycle GO:0045787 92 0.129
response to organic cyclic compound GO:0014070 198 0.129
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.129
regulation of mitotic cell cycle GO:0007346 126 0.127
macromolecule catabolic process GO:0009057 281 0.125
adult behavior GO:0030534 135 0.124
negative regulation of organ growth GO:0046621 17 0.123
regulation of actin cytoskeleton organization GO:0032956 84 0.123
dna replication GO:0006260 52 0.122
keratinocyte differentiation GO:0030216 48 0.122
response to oxidative stress GO:0006979 123 0.121
regulation of circadian rhythm GO:0042752 58 0.121
retina development in camera type eye GO:0060041 119 0.121
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.118
axon guidance GO:0007411 141 0.117
regulation of neuron death GO:1901214 134 0.115
protein deacylation GO:0035601 36 0.114
regulation of translation GO:0006417 71 0.114
chromosome segregation GO:0007059 48 0.113
protein alkylation GO:0008213 81 0.113
negative regulation of cell development GO:0010721 169 0.112
chemotaxis GO:0006935 247 0.112
Fly
negative regulation of cell cycle GO:0045786 123 0.112
negative regulation of cell cycle process GO:0010948 69 0.112
nuclear transport GO:0051169 139 0.112
cell adhesion GO:0007155 329 0.109
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.109
embryonic digestive tract morphogenesis GO:0048557 17 0.109
Worm
dna alkylation GO:0006305 43 0.104
positive regulation of cell cycle phase transition GO:1901989 17 0.103
androgen receptor signaling pathway GO:0030521 8 0.103
epithelial cell migration GO:0010631 63 0.102
segmentation GO:0035282 93 0.102
Fly
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.102
circulatory system process GO:0003013 197 0.102
placenta development GO:0001890 140 0.102
regulation of cell cycle g1 s phase transition GO:1902806 35 0.101
regulation of cell motility GO:2000145 236 0.101
modification by host of symbiont morphology or physiology GO:0051851 12 0.101
retina morphogenesis in camera type eye GO:0060042 45 0.101
mitotic cell cycle process GO:1903047 159 0.101
regulation of wnt signaling pathway GO:0030111 123 0.100
b cell activation GO:0042113 161 0.099
determination of adult lifespan GO:0008340 11 0.098
Fly
positive regulation of dna templated transcription elongation GO:0032786 2 0.098
protein modification by small protein conjugation or removal GO:0070647 207 0.097
wound healing GO:0042060 157 0.094
embryonic appendage morphogenesis GO:0035113 126 0.094
regulation of dna binding GO:0051101 39 0.094
positive regulation of dendrite development GO:1900006 21 0.092
response to decreased oxygen levels GO:0036293 59 0.092
g1 s transition of mitotic cell cycle GO:0000082 57 0.091
cellular macromolecule catabolic process GO:0044265 206 0.091
regulation of cellular component biogenesis GO:0044087 181 0.090
tongue development GO:0043586 18 0.090
regulation of mrna splicing via spliceosome GO:0048024 32 0.089
response to oxygen levels GO:0070482 62 0.089
phagocytosis GO:0006909 66 0.089
3 utr mediated mrna stabilization GO:0070935 2 0.089
neuron migration GO:0001764 122 0.087
viral transcription GO:0019083 3 0.086
respiratory tube development GO:0030323 167 0.085
female gamete generation GO:0007292 74 0.085
positive regulation of binding GO:0051099 49 0.085
nucleocytoplasmic transport GO:0006913 139 0.084
regulation of mitotic cell cycle phase transition GO:1901990 73 0.084
receptor biosynthetic process GO:0032800 3 0.084
Human
rna splicing GO:0008380 54 0.084
muscle tissue development GO:0060537 308 0.083
sensory perception of light stimulus GO:0050953 54 0.083
negative regulation of wnt signaling pathway GO:0030178 73 0.083
regulation of histone acetylation GO:0035065 19 0.082
regeneration GO:0031099 38 0.082
negative regulation of cellular amine metabolic process GO:0033239 1 0.082
locomotory behavior GO:0007626 195 0.080
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.079
viral gene expression GO:0019080 3 0.077
skeletal system development GO:0001501 356 0.077
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.076
oocyte construction GO:0007308 2 0.076
mesoderm development GO:0007498 100 0.075
fungiform papilla morphogenesis GO:0061197 5 0.075
positive regulation of cell death GO:0010942 224 0.074
sensory perception GO:0007600 245 0.074
regulation of peptide hormone secretion GO:0090276 75 0.073
odontogenesis GO:0042476 78 0.073
regulation of actin filament based process GO:0032970 99 0.072
blastoderm segmentation GO:0007350 13 0.071
Fly
cellular response to oxidative stress GO:0034599 76 0.071
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.071
Fly
negative regulation of viral process GO:0048525 23 0.069
response to organonitrogen compound GO:0010243 246 0.069
myeloid leukocyte differentiation GO:0002573 119 0.069
response to lipopolysaccharide GO:0032496 128 0.069
positive regulation of programmed cell death GO:0043068 218 0.069
multicellular organism growth GO:0035264 161 0.069
circadian rhythm GO:0007623 114 0.068
protein methylation GO:0006479 81 0.068
dna repair GO:0006281 107 0.068
chromatin remodeling GO:0006338 32 0.067
Human
gland development GO:0048732 330 0.067
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.067
regulation of muscle tissue development GO:1901861 97 0.066
epithelium migration GO:0090132 63 0.066
fat cell differentiation GO:0045444 160 0.065
skeletal muscle cell differentiation GO:0035914 66 0.065
negative regulation of striated muscle tissue development GO:0045843 18 0.065
limbic system development GO:0021761 72 0.065
nucleosome positioning GO:0016584 4 0.064
small gtpase mediated signal transduction GO:0007264 97 0.064
Worm
respiratory system development GO:0060541 190 0.063
maintenance of location GO:0051235 89 0.062
regulation of ras protein signal transduction GO:0046578 114 0.062
Worm
cellular homeostasis GO:0019725 240 0.061
nuclear mrna surveillance GO:0071028 1 0.061
odontogenesis of dentin containing tooth GO:0042475 66 0.060
positive regulation of apoptotic process GO:0043065 217 0.060
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.060
response to extracellular stimulus GO:0009991 127 0.059
Worm
double strand break repair via nonhomologous end joining GO:0006303 10 0.058
hair cycle GO:0042633 90 0.058
neuron projection extension GO:1990138 64 0.057
biofilm formation GO:0042710 1 0.057
epithelial to mesenchymal transition GO:0001837 47 0.057
oocyte axis specification GO:0007309 2 0.057
regulation of response to dna damage stimulus GO:2001020 34 0.057
mrna processing GO:0006397 63 0.057
regulation of kinase activity GO:0043549 249 0.057
reproductive behavior GO:0019098 32 0.056
blastocyst development GO:0001824 80 0.056
dna templated transcription termination GO:0006353 4 0.055
positive regulation of mitotic cell cycle GO:0045931 41 0.055
regulation of leukocyte differentiation GO:1902105 159 0.054
ameboidal type cell migration GO:0001667 128 0.054
cerebellum development GO:0021549 77 0.053
negative regulation of multi organism process GO:0043901 68 0.053
regulation of epithelial cell migration GO:0010632 35 0.053
muscle cell differentiation GO:0042692 261 0.053
mrna metabolic process GO:0016071 84 0.052
muscle system process GO:0003012 141 0.052
maternal determination of anterior posterior axis embryo GO:0008358 2 0.052
oocyte anterior posterior axis specification GO:0007314 2 0.052
negative regulation of intracellular steroid hormone receptor signaling pathway GO:0033144 11 0.051
regulation of chromatin organization GO:1902275 57 0.051
inflammatory response GO:0006954 244 0.051
multicellular organismal reproductive behavior GO:0033057 23 0.051
protein modification by small protein conjugation GO:0032446 187 0.050
metaphase plate congression GO:0051310 2 0.050
regulation of cardiac muscle tissue development GO:0055024 31 0.049
positive regulation of glial cell differentiation GO:0045687 21 0.049
epithelial cell development GO:0002064 159 0.049
lens development in camera type eye GO:0002088 62 0.049
myofibril assembly GO:0030239 34 0.049
regulation of cell migration GO:0030334 219 0.049
cytoplasmic transport GO:0016482 234 0.048
erythrocyte differentiation GO:0030218 88 0.048
lymphocyte differentiation GO:0030098 242 0.048
canonical wnt signaling pathway GO:0060070 130 0.048
metencephalon development GO:0022037 89 0.047
negative regulation of epithelial cell proliferation GO:0050680 64 0.046
nucleotide excision repair GO:0006289 13 0.046
jak stat cascade GO:0007259 42 0.046
myeloid cell differentiation GO:0030099 233 0.045
histone lysine methylation GO:0034968 50 0.045
engulfment of apoptotic cell GO:0043652 3 0.044
megakaryocyte differentiation GO:0030219 26 0.044
oogenesis GO:0048477 56 0.043
negative regulation of chromatin modification GO:1903309 19 0.043
negative regulation of circadian rhythm GO:0042754 8 0.042
skeletal muscle organ development GO:0060538 163 0.042
muscle cell proliferation GO:0033002 52 0.042
hair follicle development GO:0001942 85 0.042
response to transforming growth factor beta GO:0071559 88 0.041
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.041
cellular carbohydrate metabolic process GO:0044262 119 0.041
carbohydrate derivative biosynthetic process GO:1901137 183 0.040
developmental cell growth GO:0048588 84 0.040
regulation of jak stat cascade GO:0046425 34 0.040
amide transport GO:0042886 138 0.040
macromolecular complex disassembly GO:0032984 43 0.040
palate development GO:0060021 76 0.040
cellular response to external stimulus GO:0071496 88 0.040
Worm
regulation of synapse assembly GO:0051963 29 0.040
cell fate determination GO:0001709 32 0.039
protein kinase b signaling GO:0043491 74 0.039
positive regulation of epithelial cell proliferation GO:0050679 68 0.039
regulation of protein catabolic process GO:0042176 108 0.039
maintenance of chromatin silencing GO:0006344 2 0.039
Human
polysaccharide metabolic process GO:0005976 39 0.039
regulation of viral transcription GO:0046782 3 0.039
purine nucleotide catabolic process GO:0006195 211 0.038
mrna catabolic process GO:0006402 22 0.038
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.037
endoderm development GO:0007492 45 0.037
Mouse
regulation of organelle organization GO:0033043 289 0.037
carbohydrate homeostasis GO:0033500 128 0.037
myeloid cell homeostasis GO:0002262 114 0.037
actomyosin structure organization GO:0031032 56 0.037
mitotic cytokinesis GO:0000281 4 0.037
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.037
glucan metabolic process GO:0044042 32 0.037
regulation of chromosome organization GO:0033044 83 0.036
chromatin remodeling at centromere GO:0031055 2 0.035
regulation of cellular catabolic process GO:0031329 242 0.035
epidermal cell division GO:0010481 3 0.035
positive regulation of neuron differentiation GO:0045666 141 0.035
rna splicing via transesterification reactions GO:0000375 43 0.034
glycoprotein metabolic process GO:0009100 116 0.034
negative regulation of immune system process GO:0002683 209 0.034
tissue regeneration GO:0042246 22 0.034
positive regulation of proteolysis GO:0045862 85 0.034
Human
histone methylation GO:0016571 71 0.034
cellular chemical homeostasis GO:0055082 215 0.034
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.034
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.034
purine ribonucleotide metabolic process GO:0009150 290 0.034
digestion GO:0007586 40 0.034
regulation of protein localization GO:0032880 231 0.033
positive regulation of neuron projection development GO:0010976 79 0.033
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.033
regulation of mapk cascade GO:0043408 248 0.033
energy reserve metabolic process GO:0006112 39 0.033
regulation of chromatin modification GO:1903308 57 0.033
body morphogenesis GO:0010171 45 0.033
synapse assembly GO:0007416 56 0.032
organonitrogen compound biosynthetic process GO:1901566 192 0.032
response to tumor necrosis factor GO:0034612 26 0.032
endomembrane system organization GO:0010256 147 0.031
glucose homeostasis GO:0042593 128 0.031
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.031
cellular carbohydrate catabolic process GO:0044275 15 0.031
cognition GO:0050890 149 0.031
glycosyl compound metabolic process GO:1901657 246 0.030
establishment or maintenance of cell polarity GO:0007163 86 0.030
regulation of gliogenesis GO:0014013 50 0.030
negative regulation of secretion GO:0051048 61 0.030
rna modification GO:0009451 20 0.030
negative regulation of gene silencing GO:0060969 2 0.029
modification of morphology or physiology of other organism GO:0035821 18 0.029
regulation of dna templated transcription termination GO:0031554 1 0.027
regulation of cytokine production GO:0001817 266 0.027
protein localization to organelle GO:0033365 185 0.027
cellular polysaccharide metabolic process GO:0044264 38 0.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.027
compound eye development GO:0048749 1 0.027
regulation of membrane potential GO:0042391 192 0.027
negative regulation of heart growth GO:0061117 7 0.026
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.026
multi organism behavior GO:0051705 62 0.026
regulation of stem cell differentiation GO:2000736 50 0.026
dna recombination GO:0006310 92 0.025
negative regulation of muscle tissue development GO:1901862 20 0.025
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.025
positive regulation of mapk cascade GO:0043410 170 0.025
cell cycle g1 s phase transition GO:0044843 57 0.025
regulation of mrna stability GO:0043488 23 0.025
rna processing GO:0006396 105 0.025
blood circulation GO:0008015 195 0.025
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.025
blood vessel morphogenesis GO:0048514 285 0.025
positive regulation of defense response GO:0031349 124 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
production of molecular mediator of immune response GO:0002440 103 0.025
striated muscle tissue development GO:0014706 293 0.025
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.024
regulation of myeloid cell differentiation GO:0045637 96 0.024
histone h3 k4 trimethylation GO:0080182 5 0.024
digestive system development GO:0055123 200 0.024
Worm
notch signaling pathway GO:0007219 71 0.024
Worm
response to hypoxia GO:0001666 58 0.024
positive regulation of myeloid cell differentiation GO:0045639 43 0.024
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.024
regulation of protein stability GO:0031647 52 0.024
negative regulation of chromosome organization GO:2001251 30 0.024
histone h3 k4 methylation GO:0051568 23 0.024
hair follicle placode formation GO:0060789 5 0.023
cerebral cortex development GO:0021987 86 0.023
epithelial tube morphogenesis GO:0060562 303 0.023
convergent extension GO:0060026 14 0.023
oligodendrocyte differentiation GO:0048709 53 0.023
trna processing GO:0008033 11 0.023
hepaticobiliary system development GO:0061008 67 0.023
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.023
purine nucleoside monophosphate catabolic process GO:0009128 58 0.023
protein dna complex subunit organization GO:0071824 28 0.023
appendage morphogenesis GO:0035107 149 0.023
peptide transport GO:0015833 133 0.022
actin cytoskeleton organization GO:0030036 220 0.022
regulation of protein ubiquitination GO:0031396 52 0.022
carbohydrate catabolic process GO:0016052 32 0.022
response to starvation GO:0042594 65 0.022
regulation of system process GO:0044057 200 0.022
negative regulation of protein acetylation GO:1901984 9 0.022
response to nutrient levels GO:0031667 109 0.022
muscle cell development GO:0055001 133 0.022
negative regulation of cell cycle phase transition GO:1901988 48 0.022
neural tube patterning GO:0021532 43 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
cellular glucan metabolic process GO:0006073 32 0.021
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 18 0.021
visual perception GO:0007601 52 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.021
glycoprotein biosynthetic process GO:0009101 89 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.021
eyelid development in camera type eye GO:0061029 9 0.021
erk1 and erk2 cascade GO:0070371 77 0.021
oocyte differentiation GO:0009994 35 0.020
response to amphetamine GO:0001975 16 0.020
response to peptide GO:1901652 136 0.020
regulation of cellular response to growth factor stimulus GO:0090287 82 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
dna methylation GO:0006306 43 0.020
synapse organization GO:0050808 125 0.020
male sex differentiation GO:0046661 109 0.020
Worm

Hdac2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.208
nervous system disease DOID:863 0 0.208
central nervous system disease DOID:331 0 0.049
neurodegenerative disease DOID:1289 0 0.049
cancer DOID:162 0 0.030
disease of cellular proliferation DOID:14566 0 0.030
muscular disease DOID:0080000 0 0.021
musculoskeletal system disease DOID:17 0 0.021