Mus musculus

210 known processes

Hdac4

histone deacetylase 4

(Aliases: AI047285,4932408F19Rik)

Hdac4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to fluid shear stress GO:0071498 4 0.989
Mouse
regulation of synaptic activity GO:0060025 1 0.926
regulation of behavioral fear response GO:2000822 2 0.916
positive regulation of myeloid cell apoptotic process GO:0033034 4 0.907
positive regulation of protein homodimerization activity GO:0090073 1 0.851
cellular response to antibiotic GO:0071236 4 0.801
regulation of sarcomere organization GO:0060297 4 0.790
positive regulation of dna templated transcription elongation GO:0032786 2 0.738
dendritic spine development GO:0060996 30 0.736
mitochondrion distribution GO:0048311 4 0.731
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.714
regulation of fear response GO:1903365 2 0.694
myosin filament assembly GO:0031034 2 0.655
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.626
myosin filament organization GO:0031033 3 0.603
ventricular cardiac myofibril assembly GO:0055005 3 0.571
b cell receptor signaling pathway GO:0050853 20 0.567
glomerulus development GO:0032835 40 0.563
regulation of glutamate receptor signaling pathway GO:1900449 16 0.561
germinal center formation GO:0002467 16 0.549
monocyte differentiation GO:0030224 9 0.537
striated muscle myosin thick filament assembly GO:0071688 1 0.537
pigment cell differentiation GO:0050931 27 0.514
muscle fiber development GO:0048747 76 0.507
response to osmotic stress GO:0006970 21 0.506
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.503
skeletal myofibril assembly GO:0014866 4 0.500
regulation of adaptive immune response GO:0002819 90 0.483
cardiac muscle hypertrophy in response to stress GO:0014898 10 0.476
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 10 0.472
developmental pigmentation GO:0048066 40 0.469
cellular response to osmotic stress GO:0071470 7 0.463
positive regulation of hydrolase activity GO:0051345 148 0.462
glutamate receptor signaling pathway GO:0007215 35 0.449
leukocyte differentiation GO:0002521 342 0.440
positive regulation of alkaline phosphatase activity GO:0010694 3 0.438
embryonic skeletal system development GO:0048706 120 0.427
Zebrafish
skeletal system morphogenesis GO:0048705 203 0.427
Zebrafish
regionalization GO:0003002 337 0.424
circadian behavior GO:0048512 13 0.412
skeletal muscle myosin thick filament assembly GO:0030241 1 0.409
embryonic organ morphogenesis GO:0048562 276 0.394
Zebrafish
cellular component assembly involved in morphogenesis GO:0010927 139 0.380
megakaryocyte differentiation GO:0030219 26 0.380
adaptive immune response GO:0002250 155 0.378
transmembrane transport GO:0055085 412 0.375
urogenital system development GO:0001655 261 0.362
Mouse
cellular response to biotic stimulus GO:0071216 92 0.356
negative regulation of cell proliferation GO:0008285 296 0.348
positive regulation of macrophage apoptotic process GO:2000111 3 0.346
regulation of postsynaptic membrane potential GO:0060078 48 0.344
regulation of muscle tissue development GO:1901861 97 0.335
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.334
regulation of neurotransmitter secretion GO:0046928 29 0.329
circadian rhythm GO:0007623 114 0.329
synaptic transmission GO:0007268 329 0.318
skeletal system development GO:0001501 356 0.318
heart field specification GO:0003128 6 0.315
actin cytoskeleton organization GO:0030036 220 0.310
positive regulation of apoptotic process GO:0043065 217 0.307
Rat
melanocyte differentiation GO:0030318 25 0.301
sarcomere organization GO:0045214 24 0.301
embryonic skeletal system morphogenesis GO:0048704 91 0.293
Zebrafish
ion transmembrane transport GO:0034220 361 0.292
nephron tubule epithelial cell differentiation GO:0072160 11 0.291
cellular response to lipopolysaccharide GO:0071222 77 0.289
nephron development GO:0072006 109 0.288
regulation of ion transmembrane transporter activity GO:0032412 54 0.288
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.286
palate development GO:0060021 76 0.285
positive regulation of phosphatase activity GO:0010922 4 0.280
mitochondrial genome maintenance GO:0000002 15 0.280
regulation of neuron apoptotic process GO:0043523 122 0.280
Rat
mesenchyme development GO:0060485 152 0.280
Zebrafish
platelet morphogenesis GO:0036344 13 0.275
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.271
regulation of neuron projection development GO:0010975 169 0.270
positive regulation of leukocyte apoptotic process GO:2000108 21 0.270
syncytium formation by plasma membrane fusion GO:0000768 42 0.270
regulation of membrane potential GO:0042391 192 0.269
membrane depolarization GO:0051899 64 0.269
organelle assembly GO:0070925 177 0.268
neurotransmitter secretion GO:0007269 62 0.267
dephosphorylation GO:0016311 129 0.263
midgut development GO:0007494 4 0.255
cardiac conduction GO:0061337 17 0.255
positive regulation of cell death GO:0010942 224 0.253
Rat
regulation of synaptic plasticity GO:0048167 87 0.253
regulation of actin cytoskeleton organization GO:0032956 84 0.252
cellular response to inorganic substance GO:0071241 37 0.250
rhythmic process GO:0048511 174 0.247
renal system development GO:0072001 225 0.246
Mouse
immune response regulating signaling pathway GO:0002764 125 0.243
glomerulus morphogenesis GO:0072102 10 0.240
multicellular organismal response to stress GO:0033555 62 0.240
Mouse
regulation of defense response GO:0031347 233 0.239
cellular response to calcium ion GO:0071277 14 0.236
lipid localization GO:0010876 126 0.236
regulation of hydrolase activity GO:0051336 246 0.236
regulation of dendritic spine development GO:0060998 22 0.232
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.230
regulation of leukocyte proliferation GO:0070663 121 0.230
b cell proliferation GO:0042100 53 0.229
cellular response to molecule of bacterial origin GO:0071219 83 0.228
muscle cell differentiation GO:0042692 261 0.221
mitochondrion organization GO:0007005 134 0.221
skeletal muscle cell differentiation GO:0035914 66 0.217
positive regulation of leukocyte proliferation GO:0070665 73 0.216
lymphocyte proliferation GO:0046651 164 0.215
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.212
regulation of lymphocyte activation GO:0051249 240 0.212
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 8 0.211
cellular response to lipid GO:0071396 145 0.210
regulation of lymphocyte proliferation GO:0050670 117 0.210
positive regulation of osteoblast differentiation GO:0045669 34 0.210
regulation of germinal center formation GO:0002634 10 0.209
regulation of heart contraction GO:0008016 77 0.208
regulation of b cell proliferation GO:0030888 39 0.207
bone development GO:0060348 120 0.203
hematopoietic progenitor cell differentiation GO:0002244 143 0.202
ossification GO:0001503 216 0.201
positive regulation of muscle cell differentiation GO:0051149 39 0.200
regulation of osteoblast differentiation GO:0045667 67 0.199
regulation of binding GO:0051098 111 0.199
Human
myofibril assembly GO:0030239 34 0.196
specification of organ identity GO:0010092 30 0.196
myeloid leukocyte differentiation GO:0002573 119 0.192
negative regulation of neuron apoptotic process GO:0043524 92 0.190
response to lipopolysaccharide GO:0032496 128 0.190
regulation of myeloid cell differentiation GO:0045637 96 0.189
positive regulation of behavioral fear response GO:2000987 1 0.188
multicellular organismal signaling GO:0035637 91 0.188
activation of immune response GO:0002253 138 0.188
positive regulation of behavior GO:0048520 40 0.187
epithelial cell differentiation involved in kidney development GO:0035850 23 0.187
regulation of b cell activation GO:0050864 81 0.186
myotube differentiation GO:0014902 105 0.186
regulation of transmembrane transport GO:0034762 128 0.185
lymphocyte homeostasis GO:0002260 64 0.183
locomotor rhythm GO:0045475 8 0.182
secondary heart field specification GO:0003139 6 0.180
blood vessel morphogenesis GO:0048514 285 0.180
Mouse
locomotory behavior GO:0007626 195 0.180
ventricular cardiac muscle cell differentiation GO:0055012 17 0.180
mesenchymal cell differentiation GO:0048762 107 0.177
Zebrafish
leukocyte proliferation GO:0070661 172 0.177
mitochondrion localization GO:0051646 9 0.177
regulation of cell activation GO:0050865 289 0.177
regulation of cellular amine metabolic process GO:0033238 20 0.175
immune response activating signal transduction GO:0002757 116 0.174
antigen receptor mediated signaling pathway GO:0050851 64 0.173
positive regulation of cardiac muscle cell differentiation GO:2000727 6 0.173
neuron migration GO:0001764 122 0.171
cellular response to toxic substance GO:0097237 7 0.170
response to molecule of bacterial origin GO:0002237 143 0.169
regulation of myotube differentiation GO:0010830 62 0.168
regulation of ion transport GO:0043269 215 0.166
regulation of neurotransmitter transport GO:0051588 35 0.166
dendrite development GO:0016358 115 0.166
positive regulation of biomineral tissue development GO:0070169 12 0.164
muscle adaptation GO:0043500 39 0.164
negative regulation of epithelial cell proliferation GO:0050680 64 0.163
positive regulation of lymphocyte proliferation GO:0050671 70 0.163
positive regulation of b cell activation GO:0050871 49 0.160
blood vessel remodeling GO:0001974 33 0.159
leukocyte homeostasis GO:0001776 79 0.158
regulation of cellular ketone metabolic process GO:0010565 66 0.157
histone modification GO:0016570 159 0.157
Human Rat Fly
regulation of receptor activity GO:0010469 41 0.156
embryonic viscerocranium morphogenesis GO:0048703 8 0.155
muscle system process GO:0003012 141 0.154
regulation of synaptic transmission glutamatergic GO:0051966 19 0.153
regulation of striated muscle cell differentiation GO:0051153 81 0.153
b cell homeostasis GO:0001782 34 0.152
neural crest cell differentiation GO:0014033 54 0.152
Zebrafish
regulation of neuron differentiation GO:0045664 281 0.151
Worm
epithelial tube morphogenesis GO:0060562 303 0.150
Mouse
positive regulation of cell activation GO:0050867 158 0.148
synapse organization GO:0050808 125 0.148
positive regulation of defense response GO:0031349 124 0.148
bone mineralization GO:0030282 54 0.147
cell type specific apoptotic process GO:0097285 268 0.147
Rat
regulation of actin filament based process GO:0032970 99 0.146
regulation of protein homodimerization activity GO:0043496 4 0.146
regulation of cardiac muscle cell differentiation GO:2000725 9 0.145
endochondral bone morphogenesis GO:0060350 50 0.145
striated muscle adaptation GO:0014888 26 0.145
regulation of cell projection organization GO:0031344 206 0.144
Rat
regulation of transporter activity GO:0032409 57 0.143
cardiac chamber development GO:0003205 108 0.143
myeloid cell apoptotic process GO:0033028 22 0.142
cellular amine metabolic process GO:0044106 44 0.141
cardiac myofibril assembly GO:0055003 12 0.140
stem cell differentiation GO:0048863 268 0.139
Zebrafish
regulation of myeloid cell apoptotic process GO:0033032 19 0.137
positive regulation of striated muscle cell differentiation GO:0051155 35 0.137
cellular response to drug GO:0035690 15 0.137
striated muscle cell development GO:0055002 125 0.136
actomyosin structure organization GO:0031032 56 0.136
positive regulation of lymphocyte activation GO:0051251 140 0.136
epithelial cell proliferation GO:0050673 174 0.134
regulation of system process GO:0044057 200 0.133
bone morphogenesis GO:0060349 78 0.133
negative regulation of protein metabolic process GO:0051248 282 0.132
regulation of neurotransmitter levels GO:0001505 87 0.131
regulation of cardiac muscle tissue development GO:0055024 31 0.131
syncytium formation GO:0006949 43 0.128
regulation of cellular component biogenesis GO:0044087 181 0.128
Rat
regulation of cytoskeleton organization GO:0051493 122 0.128
cartilage morphogenesis GO:0060536 11 0.127
homeostasis of number of cells GO:0048872 210 0.126
cellular response to metal ion GO:0071248 31 0.126
positive regulation of b cell proliferation GO:0030890 24 0.126
neurotransmitter transport GO:0006836 76 0.126
positive regulation of dephosphorylation GO:0035306 6 0.125
tissue remodeling GO:0048771 102 0.124
kidney development GO:0001822 213 0.124
connective tissue development GO:0061448 179 0.123
leukocyte apoptotic process GO:0071887 71 0.123
digestive tract development GO:0048565 190 0.123
response to antibiotic GO:0046677 11 0.122
regulation of organelle assembly GO:1902115 19 0.122
cardiac muscle hypertrophy GO:0003300 23 0.122
cardiocyte differentiation GO:0035051 87 0.120
neuron neuron synaptic transmission GO:0007270 69 0.119
positive regulation of fear response GO:1903367 1 0.118
amine metabolic process GO:0009308 45 0.116
response to fluid shear stress GO:0034405 7 0.115
Mouse
muscle hypertrophy GO:0014896 24 0.115
digestive system development GO:0055123 200 0.113
mesoderm development GO:0007498 100 0.113
chondrocyte differentiation GO:0002062 72 0.113
cell fate commitment GO:0045165 210 0.111
maintenance of location GO:0051235 89 0.110
lipid storage GO:0019915 36 0.110
cellular response to organic cyclic compound GO:0071407 87 0.110
positive regulation of cell development GO:0010720 237 0.110
fear response GO:0042596 33 0.109
regulation of organelle organization GO:0033043 289 0.108
striated muscle hypertrophy GO:0014897 24 0.108
replacement ossification GO:0036075 26 0.107
regulation of epithelial cell proliferation GO:0050678 141 0.107
positive regulation of cardiac muscle tissue development GO:0055025 19 0.106
response to inorganic substance GO:0010035 96 0.106
heart valve morphogenesis GO:0003179 21 0.105
second messenger mediated signaling GO:0019932 73 0.104
nephron epithelium development GO:0072009 92 0.104
cognition GO:0050890 149 0.104
Fly
cellular protein complex assembly GO:0043623 116 0.103
regulation of ion transmembrane transport GO:0034765 119 0.103
positive regulation of ossification GO:0045778 47 0.103
muscle cell proliferation GO:0033002 52 0.102
Rat
heart contraction GO:0060047 93 0.102
positive regulation of striated muscle tissue development GO:0045844 31 0.102
circulatory system process GO:0003013 197 0.101
organelle localization GO:0051640 179 0.100
negative regulation of cellular component organization GO:0051129 194 0.100
response to organic cyclic compound GO:0014070 198 0.100
Mouse
covalent chromatin modification GO:0016569 163 0.100
Human Rat Fly
cardiac muscle cell development GO:0055013 39 0.100
chromatin organization GO:0006325 206 0.099
Human Rat Fly
striated muscle tissue development GO:0014706 293 0.099
regulation of secretion GO:0051046 274 0.099
muscle tissue development GO:0060537 308 0.099
rhythmic behavior GO:0007622 15 0.099
negative regulation of molecular function GO:0044092 258 0.098
Human
regulation of neuron death GO:1901214 134 0.098
Rat
carbohydrate metabolic process GO:0005975 230 0.098
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.098
regulation of cardiac muscle cell proliferation GO:0060043 23 0.097
positive regulation of protein binding GO:0032092 29 0.097
cartilage development GO:0051216 140 0.097
chromatin modification GO:0016568 187 0.096
Human Rat Fly
regulation of dna templated transcription in response to stress GO:0043620 9 0.095
regulation of cardiac muscle tissue growth GO:0055021 26 0.095
organ growth GO:0035265 117 0.095
cellular response to organonitrogen compound GO:0071417 145 0.095
protein deacetylation GO:0006476 32 0.095
kidney epithelium development GO:0072073 121 0.094
regulation of protein binding GO:0043393 60 0.094
Human
cardiac muscle cell differentiation GO:0055007 69 0.092
negative regulation of neuron death GO:1901215 98 0.092
carbohydrate catabolic process GO:0016052 32 0.092
negative regulation of cellular protein metabolic process GO:0032269 247 0.091
positive regulation of muscle tissue development GO:1901863 32 0.091
learning or memory GO:0007611 148 0.090
Fly
cardiac ventricle development GO:0003231 83 0.090
positive regulation of growth GO:0045927 104 0.090
platelet formation GO:0030220 12 0.090
response to muscle inactivity GO:0014870 4 0.090
cellular response to abiotic stimulus GO:0071214 56 0.090
Rat
heart process GO:0003015 94 0.088
synaptic transmission glutamatergic GO:0035249 36 0.088
inflammatory cell apoptotic process GO:0006925 11 0.087
humoral immune response GO:0006959 57 0.086
positive regulation of binding GO:0051099 49 0.086
heart valve development GO:0003170 23 0.085
heart formation GO:0060914 16 0.083
regulation of phosphatase activity GO:0010921 12 0.080
muscle hypertrophy in response to stress GO:0003299 10 0.080
ventricular cardiac muscle cell development GO:0055015 11 0.079
negative regulation of ossification GO:0030279 49 0.079
regulation of cell migration GO:0030334 219 0.079
Rat
regulation of muscle system process GO:0090257 80 0.078
negative regulation of striated muscle cell differentiation GO:0051154 14 0.077
Human
regulation of secretion by cell GO:1903530 249 0.077
determination of heart left right asymmetry GO:0061371 48 0.074
pigmentation GO:0043473 71 0.074
generation of precursor metabolites and energy GO:0006091 103 0.073
blood circulation GO:0008015 195 0.072
cardiac muscle tissue development GO:0048738 130 0.071
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.071
response to organonitrogen compound GO:0010243 246 0.071
Mouse
nephron tubule development GO:0072080 84 0.070
positive regulation of nervous system development GO:0051962 221 0.069
cardiac chamber morphogenesis GO:0003206 93 0.069
regulation of carbohydrate metabolic process GO:0006109 75 0.069
embryonic heart tube morphogenesis GO:0003143 51 0.068
ameboidal type cell migration GO:0001667 128 0.068
Zebrafish
behavioral fear response GO:0001662 28 0.068
regulation of heart growth GO:0060420 31 0.068
macromolecule deacylation GO:0098732 37 0.068
outflow tract morphogenesis GO:0003151 53 0.067
regulation of dephosphorylation GO:0035303 18 0.067
positive regulation of neuron differentiation GO:0045666 141 0.066
osteoblast development GO:0002076 17 0.066
myotube cell development GO:0014904 60 0.065
response to calcium ion GO:0051592 20 0.065
regulation of cellular amino acid metabolic process GO:0006521 5 0.065
cellular macromolecule catabolic process GO:0044265 206 0.064
negative regulation of glycolytic process GO:0045820 4 0.063
muscle cell development GO:0055001 133 0.063
negative regulation of phosphate metabolic process GO:0045936 184 0.062
regulation of megakaryocyte differentiation GO:0045652 7 0.061
embryonic heart tube development GO:0035050 65 0.061
neuroepithelial cell differentiation GO:0060563 37 0.061
histone deacetylation GO:0016575 26 0.061
Human Rat Fly
skeletal muscle organ development GO:0060538 163 0.060
regulation of cell motility GO:2000145 236 0.060
Rat
negative regulation of protein modification process GO:0031400 163 0.059
heart morphogenesis GO:0003007 178 0.059
regulation of alkaline phosphatase activity GO:0010692 6 0.059
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.058
positive regulation of heart growth GO:0060421 18 0.058
purine containing compound metabolic process GO:0072521 311 0.058
cell fate determination GO:0001709 32 0.058
cellular ketone metabolic process GO:0042180 84 0.057
cardiac chamber formation GO:0003207 10 0.057
dna templated transcription elongation GO:0006354 13 0.056
muscle cell fate commitment GO:0042693 11 0.056
monocarboxylic acid metabolic process GO:0032787 191 0.055
positive regulation of organ growth GO:0046622 29 0.054
response to inactivity GO:0014854 4 0.054
cardiac muscle cell proliferation GO:0060038 31 0.054
regulation of blood circulation GO:1903522 93 0.054
cardiac muscle tissue growth GO:0055017 37 0.053
behavioral defense response GO:0002209 28 0.053
fat cell differentiation GO:0045444 160 0.052
regulation of dna templated transcription elongation GO:0032784 10 0.052
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.052
regulation of organ growth GO:0046620 61 0.051
glycolytic process GO:0006096 20 0.050
regulation of cellular catabolic process GO:0031329 242 0.050
macromolecule catabolic process GO:0009057 281 0.050
body morphogenesis GO:0010171 45 0.050
Worm
negative regulation of cellular amine metabolic process GO:0033239 1 0.048
determination of left right symmetry GO:0007368 80 0.048
organonitrogen compound biosynthetic process GO:1901566 192 0.048
angiogenesis GO:0001525 201 0.048
response to oxygen levels GO:0070482 62 0.048
cell differentiation involved in kidney development GO:0061005 33 0.047
regulation of hematopoietic progenitor cell differentiation GO:1901532 18 0.047
transcription elongation from rna polymerase ii promoter GO:0006368 9 0.047
cellular carbohydrate metabolic process GO:0044262 119 0.047
regulation of biomineral tissue development GO:0070167 33 0.046
positive regulation of programmed cell death GO:0043068 218 0.046
Rat
positive regulation of cellular catabolic process GO:0031331 148 0.046
myeloid cell differentiation GO:0030099 233 0.046
response to transforming growth factor beta GO:0071559 88 0.046
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.045
compound eye development GO:0048749 1 0.045
cellular amino acid metabolic process GO:0006520 103 0.045
cellular response to hormone stimulus GO:0032870 150 0.044
Rat
antimicrobial humoral response GO:0019730 11 0.044
macrophage apoptotic process GO:0071888 7 0.043
ribose phosphate metabolic process GO:0019693 291 0.043
cardiac muscle adaptation GO:0014887 10 0.043
renal tubule morphogenesis GO:0061333 72 0.043
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.043
purine nucleotide metabolic process GO:0006163 302 0.043
negative regulation of phosphorus metabolic process GO:0010563 184 0.042
protein catabolic process GO:0030163 221 0.042
cardiac ventricle morphogenesis GO:0003208 50 0.042
apoptotic signaling pathway GO:0097190 306 0.042
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.042
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
response to drug GO:0042493 75 0.041
Rat
cytokine production GO:0001816 319 0.041
regulation of anatomical structure size GO:0090066 178 0.041
regulation of bone mineralization GO:0030500 31 0.040
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.040
Zebrafish
mapk cascade GO:0000165 281 0.039
regulation of circadian rhythm GO:0042752 58 0.039
positive regulation of bone mineralization GO:0030501 12 0.039
peptidyl amino acid modification GO:0018193 336 0.038
Human
developmental growth involved in morphogenesis GO:0060560 138 0.038
regulation of chromosome organization GO:0033044 83 0.038
synapse assembly GO:0007416 56 0.038
regulation of apoptotic signaling pathway GO:2001233 197 0.038
regulation of muscle contraction GO:0006937 49 0.037
small gtpase mediated signal transduction GO:0007264 97 0.037
protein modification by small protein conjugation GO:0032446 187 0.037
Human
ras protein signal transduction GO:0007265 77 0.037
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
protein maturation GO:0051604 176 0.036
negative regulation of growth GO:0045926 99 0.036
carbohydrate homeostasis GO:0033500 128 0.036
cell junction assembly GO:0034329 52 0.036
Mouse
regulation of cell cycle GO:0051726 281 0.035
nucleoside triphosphate catabolic process GO:0009143 205 0.035
stem cell proliferation GO:0072089 117 0.035
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.035
Rat
striated muscle contraction GO:0006941 45 0.035
regulation of synapse assembly GO:0051963 29 0.034
cardiac cell development GO:0055006 41 0.034
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 9 0.034
regulation of protein maturation GO:1903317 96 0.034
gland development GO:0048732 330 0.033
cell growth GO:0016049 130 0.033
nucleotide metabolic process GO:0009117 332 0.033
negative regulation of proteolysis GO:0045861 74 0.033
lymphocyte differentiation GO:0030098 242 0.033
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.032
neuron projection extension GO:1990138 64 0.032
regulation of proteolysis GO:0030162 164 0.032
b cell activation GO:0042113 161 0.032
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.032
positive regulation of skeletal muscle cell differentiation GO:2001016 4 0.031
regulation of feeding behavior GO:0060259 3 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
regulation of striated muscle contraction GO:0006942 25 0.031
negative regulation of intracellular signal transduction GO:1902532 167 0.031
intracellular protein transport GO:0006886 204 0.030
regulation of neural precursor cell proliferation GO:2000177 70 0.030
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.030
regulation of mapk cascade GO:0043408 248 0.030
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.030
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.030
negative regulation of protein processing GO:0010955 79 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
axonogenesis GO:0007409 274 0.029
purine nucleoside triphosphate metabolic process GO:0009144 226 0.029
hepaticobiliary system development GO:0061008 67 0.029
regulation of cell proliferation in bone marrow GO:0071863 2 0.029
immune effector process GO:0002252 321 0.029
cellular response to growth factor stimulus GO:0071363 197 0.028
stem cell development GO:0048864 219 0.028
Zebrafish
cation transport GO:0006812 399 0.028
nucleoside catabolic process GO:0009164 206 0.028
negative regulation of protein maturation GO:1903318 79 0.028
negative regulation of kinase activity GO:0033673 81 0.028
response to growth factor GO:0070848 198 0.028
cation transmembrane transport GO:0098655 266 0.028
heterocycle catabolic process GO:0046700 280 0.028
mating behavior sex discrimination GO:0048047 1 0.028
purine nucleotide biosynthetic process GO:0006164 65 0.027
mesodermal cell migration GO:0008078 4 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.027
regulation of reactive oxygen species metabolic process GO:2000377 40 0.027
Rat
cellular protein catabolic process GO:0044257 155 0.026
microtubule based process GO:0007017 236 0.026
pyruvate metabolic process GO:0006090 28 0.026
guanosine containing compound metabolic process GO:1901068 144 0.026
wound healing GO:0042060 157 0.026
positive regulation of cell proliferation in bone marrow GO:0071864 2 0.026
protein ubiquitination GO:0016567 171 0.026
purine nucleoside triphosphate catabolic process GO:0009146 203 0.026
regulation of cellular response to growth factor stimulus GO:0090287 82 0.025
regulation of cardiac muscle contraction GO:0055117 21 0.025
regulation of fat cell differentiation GO:0045598 81 0.025
protein deacylation GO:0035601 36 0.025
regulation of lipid metabolic process GO:0019216 118 0.025
regulation of protein processing GO:0070613 96 0.024
positive regulation of nucleotide catabolic process GO:0030813 88 0.024
guanosine containing compound catabolic process GO:1901069 144 0.024
regulation of carbohydrate catabolic process GO:0043470 12 0.024
forebrain development GO:0030900 302 0.024
positive regulation of neural precursor cell proliferation GO:2000179 42 0.024
Mouse
developmental cell growth GO:0048588 84 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
aromatic compound catabolic process GO:0019439 286 0.024
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023

Hdac4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.073
musculoskeletal system disease DOID:17 0 0.073
connective tissue disease DOID:65 0 0.073
bone disease DOID:0080001 0 0.045
bone development disease DOID:0080006 0 0.025
immune system disease DOID:2914 0 0.024