Mus musculus

19 known processes

Herc6

hect domain and RLD 6

(Aliases: AI451296,4930427L17Rik,CEB1,KIAA0032,2510038N07Rik,Herc5,1700121D12Rik)

Herc6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.701
viral process GO:0016032 41 0.497
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.423
interspecies interaction between organisms GO:0044419 83 0.417
defense response to virus GO:0051607 68 0.389
positive regulation of viral genome replication GO:0045070 2 0.261
protein modification by small protein conjugation or removal GO:0070647 207 0.245
immune effector process GO:0002252 321 0.225
innate immune response activating signal transduction GO:0002758 50 0.215
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.214
defense response to other organism GO:0098542 197 0.192
innate immune response GO:0045087 157 0.187
positive regulation of viral entry into host cell GO:0046598 3 0.174
protein modification by small protein conjugation GO:0032446 187 0.166
regulation of defense response GO:0031347 233 0.165
activation of innate immune response GO:0002218 56 0.159
cellular response to lipopolysaccharide GO:0071222 77 0.154
cytokine production GO:0001816 319 0.151
negative regulation of multi organism process GO:0043901 68 0.148
viral life cycle GO:0019058 36 0.147
interferon beta production GO:0032608 16 0.144
organic cyclic compound catabolic process GO:1901361 295 0.136
positive regulation of innate immune response GO:0045089 80 0.126
pattern recognition receptor signaling pathway GO:0002221 47 0.125
immune response activating signal transduction GO:0002757 116 0.124
regulation of cytokine production GO:0001817 266 0.120
regulation of innate immune response GO:0045088 91 0.119
positive regulation of defense response GO:0031349 124 0.108
activation of immune response GO:0002253 138 0.106
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.098
protein ubiquitination GO:0016567 171 0.096
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.094
cellular response to biotic stimulus GO:0071216 92 0.090
negative regulation of viral transcription GO:0032897 3 0.089
negative regulation of viral genome replication GO:0045071 10 0.089
rig i signaling pathway GO:0039529 4 0.087
cellular response to lipid GO:0071396 145 0.087
regulation of defense response to virus GO:0050688 18 0.086
regulation of multi organism process GO:0043900 111 0.086
myeloid cell differentiation GO:0030099 233 0.079
nucleoside phosphate metabolic process GO:0006753 338 0.078
response to lipopolysaccharide GO:0032496 128 0.078
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.078
negative regulation of viral process GO:0048525 23 0.078
regulation of reactive oxygen species metabolic process GO:2000377 40 0.077
aromatic compound catabolic process GO:0019439 286 0.077
reactive oxygen species metabolic process GO:0072593 84 0.077
negative regulation of cellular protein metabolic process GO:0032269 247 0.075
cellular response to molecule of bacterial origin GO:0071219 83 0.073
regulation of response to biotic stimulus GO:0002831 38 0.071
purine nucleotide metabolic process GO:0006163 302 0.071
viral genome replication GO:0019079 17 0.069
negative regulation of cellular component organization GO:0051129 194 0.068
response to molecule of bacterial origin GO:0002237 143 0.068
type i interferon production GO:0032606 29 0.065
regulation of viral release from host cell GO:1902186 6 0.064
immune response regulating signaling pathway GO:0002764 125 0.064
cellular response to interferon beta GO:0035458 21 0.063
negative regulation of protein metabolic process GO:0051248 282 0.062
viral gene expression GO:0019080 3 0.062
macromolecule catabolic process GO:0009057 281 0.059
organophosphate catabolic process GO:0046434 232 0.059
nucleocytoplasmic transport GO:0006913 139 0.058
cellular response to interferon alpha GO:0035457 4 0.058
negative regulation of cell development GO:0010721 169 0.058
glycosyl compound metabolic process GO:1901657 246 0.057
cellular nitrogen compound catabolic process GO:0044270 280 0.056
cellular response to cytokine stimulus GO:0071345 189 0.055
protein polyubiquitination GO:0000209 33 0.054
intracellular protein transport GO:0006886 204 0.054
posttranscriptional regulation of gene expression GO:0010608 155 0.051
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.051
ubiquitin dependent protein catabolic process GO:0006511 129 0.051
negative regulation of immune system process GO:0002683 209 0.050
negative regulation of nervous system development GO:0051961 156 0.050
protein catabolic process GO:0030163 221 0.050
positive regulation of immune effector process GO:0002699 107 0.050
defense response to bacterium GO:0042742 119 0.050
response to organic cyclic compound GO:0014070 198 0.050
purine containing compound catabolic process GO:0072523 213 0.048
positive regulation of rig i signaling pathway GO:1900246 1 0.048
nucleobase containing small molecule metabolic process GO:0055086 352 0.047
extrinsic apoptotic signaling pathway GO:0097191 126 0.047
heterocycle catabolic process GO:0046700 280 0.047
cytoplasmic transport GO:0016482 234 0.047
mapk cascade GO:0000165 281 0.047
cellular response to dna damage stimulus GO:0006974 207 0.047
negative regulation of interleukin 6 production GO:0032715 17 0.046
positive regulation of interferon alpha production GO:0032727 4 0.046
cellular macromolecule catabolic process GO:0044265 206 0.046
negative regulation of cell proliferation GO:0008285 296 0.046
regulation of cellular component biogenesis GO:0044087 181 0.045
erythrocyte differentiation GO:0030218 88 0.045
purine ribonucleotide metabolic process GO:0009150 290 0.045
ribonucleoside catabolic process GO:0042454 206 0.044
modification dependent protein catabolic process GO:0019941 133 0.042
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 4 0.041
ribose phosphate metabolic process GO:0019693 291 0.040
negative regulation of viral release from host cell GO:1902187 6 0.040
organonitrogen compound catabolic process GO:1901565 264 0.039
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.038
purine containing compound metabolic process GO:0072521 311 0.038
nucleoside triphosphate metabolic process GO:0009141 230 0.038
regulation of interferon beta production GO:0032648 13 0.038
negative regulation of defense response GO:0031348 77 0.037
purine ribonucleoside metabolic process GO:0046128 241 0.037
glycosyl compound catabolic process GO:1901658 206 0.037
protein oligomerization GO:0051259 67 0.037
positive regulation of hydrolase activity GO:0051345 148 0.037
carbohydrate metabolic process GO:0005975 230 0.037
regulation of cell activation GO:0050865 289 0.036
negative regulation of molecular function GO:0044092 258 0.036
movement in environment of other organism involved in symbiotic interaction GO:0052192 15 0.036
nucleoside metabolic process GO:0009116 246 0.036
modification dependent macromolecule catabolic process GO:0043632 133 0.036
regulation of hydrolase activity GO:0051336 246 0.036
nucleoside phosphate catabolic process GO:1901292 222 0.035
i kappab kinase nf kappab signaling GO:0007249 85 0.035
regulation of viral genome replication GO:0045069 13 0.035
regulation of interleukin 6 production GO:0032675 55 0.035
purine ribonucleotide catabolic process GO:0009154 208 0.034
purine nucleoside catabolic process GO:0006152 205 0.034
interleukin 6 production GO:0032635 58 0.034
positive regulation of actin nucleation GO:0051127 3 0.034
regulation of cell cycle GO:0051726 281 0.034
purine ribonucleoside catabolic process GO:0046130 205 0.033
spleen development GO:0048536 39 0.033
viral transcription GO:0019083 3 0.033
regulation of cellular catabolic process GO:0031329 242 0.033
dna metabolic process GO:0006259 303 0.033
regulation of actin nucleation GO:0051125 4 0.032
nucleoside triphosphate catabolic process GO:0009143 205 0.032
regulation of type i interferon production GO:0032479 22 0.032
cellular ketone metabolic process GO:0042180 84 0.032
negative regulation of cytokine production GO:0001818 84 0.032
myeloid leukocyte differentiation GO:0002573 119 0.031
positive regulation of cytokine production GO:0001819 174 0.031
nucleotide metabolic process GO:0009117 332 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.031
regulation of organelle organization GO:0033043 289 0.031
cellular protein catabolic process GO:0044257 155 0.031
nucleoside catabolic process GO:0009164 206 0.031
toll like receptor signaling pathway GO:0002224 38 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.031
purine nucleoside metabolic process GO:0042278 241 0.030
cellular amino acid metabolic process GO:0006520 103 0.029
regulation of mapk cascade GO:0043408 248 0.029
cellular amine metabolic process GO:0044106 44 0.029
organelle assembly GO:0070925 177 0.029
homeostasis of number of cells GO:0048872 210 0.029
apoptotic signaling pathway GO:0097190 306 0.029
nlrp3 inflammasome complex assembly GO:0044546 5 0.029
response to interferon beta GO:0035456 22 0.029
regulation of intracellular transport GO:0032386 159 0.028
positive regulation of mapk cascade GO:0043410 170 0.028
cellular protein complex assembly GO:0043623 116 0.028
carbohydrate derivative catabolic process GO:1901136 231 0.028
leukocyte differentiation GO:0002521 342 0.027
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.027
nucleotide catabolic process GO:0009166 217 0.027
entry into host GO:0044409 15 0.027
spermatogenesis GO:0007283 284 0.027
myeloid cell homeostasis GO:0002262 114 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
ribonucleoside metabolic process GO:0009119 245 0.026
cellular lipid metabolic process GO:0044255 323 0.026
leukocyte mediated immunity GO:0002443 174 0.026
natural killer cell proliferation GO:0001787 3 0.026
interaction with host GO:0051701 22 0.026
regulation of viral transcription GO:0046782 3 0.026
hematopoietic progenitor cell differentiation GO:0002244 143 0.026
negative regulation of phosphate metabolic process GO:0045936 184 0.026
stem cell differentiation GO:0048863 268 0.026
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
monocarboxylic acid metabolic process GO:0032787 191 0.025
single organism nuclear import GO:1902593 95 0.025
lipid localization GO:0010876 126 0.025
nucleoside monophosphate metabolic process GO:0009123 85 0.025
lymphocyte differentiation GO:0030098 242 0.025
membrane organization GO:0061024 245 0.025
cell type specific apoptotic process GO:0097285 268 0.025
protein import into nucleus GO:0006606 95 0.025
regulation of protein localization GO:0032880 231 0.025
cellular amide metabolic process GO:0043603 58 0.024
regulation of rig i signaling pathway GO:0039535 2 0.024
pre mirna processing GO:0031054 3 0.024
protein localization to organelle GO:0033365 185 0.024
protein processing GO:0016485 163 0.024
protein localization to nucleus GO:0034504 121 0.024
response to organonitrogen compound GO:0010243 246 0.024
regulation of leukocyte differentiation GO:1902105 159 0.023
male gamete generation GO:0048232 285 0.023
compound eye development GO:0048749 1 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.023
purine nucleoside triphosphate catabolic process GO:0009146 203 0.023
citrate metabolic process GO:0006101 3 0.023
regulation of defense response to virus by host GO:0050691 8 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
natural killer cell mediated cytotoxicity GO:0042267 29 0.023
protein maturation GO:0051604 176 0.022
skin development GO:0043588 220 0.022
cell activation involved in immune response GO:0002263 126 0.022
gene silencing by mirna GO:0035195 10 0.022
small gtpase mediated signal transduction GO:0007264 97 0.022
ribonucleoside monophosphate catabolic process GO:0009158 57 0.022
response to dsrna GO:0043331 30 0.022
proteasomal protein catabolic process GO:0010498 98 0.022
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.022
regulation of toll like receptor signaling pathway GO:0034121 20 0.022
protein import GO:0017038 101 0.021
muscle cell differentiation GO:0042692 261 0.021
b cell activation GO:0042113 161 0.021
positive regulation of lymphocyte activation GO:0051251 140 0.021
regulation of protein catabolic process GO:0042176 108 0.021
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.021
regulation of peptidase activity GO:0052547 96 0.021
regulation of natural killer cell mediated immunity GO:0002715 19 0.021
cytokine mediated signaling pathway GO:0019221 115 0.021
positive regulation of proteolysis GO:0045862 85 0.021
b cell activation involved in immune response GO:0002312 50 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
stem cell development GO:0048864 219 0.020
regulation of b cell activation GO:0050864 81 0.020
positive regulation of viral process GO:0048524 5 0.020
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.020
regulation of protein complex assembly GO:0043254 83 0.020
positive regulation of cell activation GO:0050867 158 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
entry into other organism involved in symbiotic interaction GO:0051828 15 0.020
regulation of interferon alpha production GO:0032647 5 0.019
cellular component assembly involved in morphogenesis GO:0010927 139 0.019
positive regulation of protein catabolic process GO:0045732 60 0.019
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.019
chromatin organization GO:0006325 206 0.019
response to interferon gamma GO:0034341 34 0.019
protein targeting GO:0006605 143 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.019
translation GO:0006412 93 0.019
negative regulation of viral entry into host cell GO:0046597 10 0.019
cell killing GO:0001906 67 0.019
organism emergence from protective structure GO:0071684 4 0.019
ossification GO:0001503 216 0.019
regulation of cytoplasmic transport GO:1903649 112 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
multicellular organism growth GO:0035264 161 0.019
microtubule based process GO:0007017 236 0.019
regulation of hormone levels GO:0010817 211 0.018
transmission of nerve impulse GO:0019226 76 0.018
regulation of endopeptidase activity GO:0052548 89 0.018
positive regulation of type i interferon production GO:0032481 14 0.018
epidermis development GO:0008544 187 0.018
multicellular organismal signaling GO:0035637 91 0.018
fatty acid metabolic process GO:0006631 121 0.018
purine nucleoside monophosphate metabolic process GO:0009126 81 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
regulation of t cell activation GO:0050863 170 0.018
regulation of transferase activity GO:0051338 263 0.018
peptidyl amino acid modification GO:0018193 336 0.018
regulation of proteolysis GO:0030162 164 0.018
maintenance of location GO:0051235 89 0.018
atp catabolic process GO:0006200 55 0.018
natural killer cell activation GO:0030101 44 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
b cell differentiation GO:0030183 78 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.017
regulation of protein transport GO:0051223 163 0.017
neuronal action potential GO:0019228 54 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
regulation of leukocyte mediated immunity GO:0002703 104 0.017
carbohydrate catabolic process GO:0016052 32 0.017
nuclear import GO:0051170 95 0.017
entry into host cell GO:0030260 15 0.017
mitotic cell cycle GO:0000278 195 0.017
establishment of protein localization to organelle GO:0072594 118 0.017
action potential GO:0001508 78 0.017
regulation of cysteine type endopeptidase activity GO:2000116 65 0.017
toll like receptor 7 signaling pathway GO:0034154 4 0.016
nuclear transport GO:0051169 139 0.016
ion transmembrane transport GO:0034220 361 0.016
positive regulation of mirna metabolic process GO:2000630 1 0.016
t cell activation GO:0042110 289 0.016
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.016
regulation of cellular ketone metabolic process GO:0010565 66 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
taurine metabolic process GO:0019530 4 0.016
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.016
glycosylation GO:0070085 62 0.016
nucleotide biosynthetic process GO:0009165 78 0.016
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.016
progesterone metabolic process GO:0042448 4 0.016
nitrogen compound transport GO:0071705 271 0.016
transmembrane transport GO:0055085 412 0.015
lung development GO:0030324 164 0.015
regulation of cell migration GO:0030334 219 0.015
cell adhesion GO:0007155 329 0.015
regulation of membrane potential GO:0042391 192 0.015
digestive tract development GO:0048565 190 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.015
glucose homeostasis GO:0042593 128 0.015
ras protein signal transduction GO:0007265 77 0.015
sensory organ morphogenesis GO:0090596 242 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
amine metabolic process GO:0009308 45 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
movement in host environment GO:0052126 15 0.015
spermatid differentiation GO:0048515 115 0.015
germ cell development GO:0007281 185 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
anion transport GO:0006820 177 0.014
urogenital system development GO:0001655 261 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
negative regulation of reactive oxygen species metabolic process GO:2000378 10 0.014
carbohydrate homeostasis GO:0033500 128 0.014
glial cell differentiation GO:0010001 131 0.014
gland development GO:0048732 330 0.014
tumor necrosis factor production GO:0032640 50 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
male sex differentiation GO:0046661 109 0.014
skeletal system development GO:0001501 356 0.014
regulation of translation GO:0006417 71 0.014
gene silencing by rna GO:0031047 19 0.014
gene silencing GO:0016458 38 0.014
extracellular matrix organization GO:0030198 147 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
oxidation reduction process GO:0055114 342 0.014
regulation of cell motility GO:2000145 236 0.014
regulation of tumor necrosis factor production GO:0032680 49 0.014
actin polymerization or depolymerization GO:0008154 54 0.014
ear development GO:0043583 200 0.014
regulation of protein ubiquitination GO:0031396 52 0.014
natural killer cell mediated immunity GO:0002228 29 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.014
regulation of cellular amino acid metabolic process GO:0006521 5 0.014
alpha amino acid metabolic process GO:1901605 59 0.014
negative regulation of immune effector process GO:0002698 55 0.014
leukocyte mediated cytotoxicity GO:0001909 62 0.014
dna repair GO:0006281 107 0.014
hatching GO:0035188 4 0.014
extracellular structure organization GO:0043062 148 0.014
chromatin modification GO:0016568 187 0.014
production of molecular mediator of immune response GO:0002440 103 0.014
rna processing GO:0006396 105 0.014
digestive system development GO:0055123 200 0.014
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.014
regulation of neuron differentiation GO:0045664 281 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
regulation of cell killing GO:0031341 40 0.013
sulfur compound metabolic process GO:0006790 100 0.013
positive regulation of cell cycle GO:0045787 92 0.013
positive regulation of peptidase activity GO:0010952 49 0.013
cation transmembrane transport GO:0098655 266 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
protein polymerization GO:0051258 57 0.013
viral entry into host cell GO:0046718 15 0.013
response to type i interferon GO:0034340 12 0.013
cellular response to interferon gamma GO:0071346 25 0.013
muscle tissue development GO:0060537 308 0.013
spermatid development GO:0007286 108 0.013
regulation of schwann cell proliferation GO:0010624 2 0.013
generation of precursor metabolites and energy GO:0006091 103 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
regulation of interleukin 8 production GO:0032677 3 0.013
atp metabolic process GO:0046034 75 0.013
stem cell maintenance GO:0019827 130 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
regulation of lymphocyte mediated immunity GO:0002706 84 0.013
regulation of protein kinase activity GO:0045859 232 0.013
regulation of intracellular protein transport GO:0033157 82 0.013
axon ensheathment GO:0008366 76 0.013
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.013
posttranscriptional gene silencing by rna GO:0035194 10 0.013
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.013
lipid homeostasis GO:0055088 63 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
positive regulation of myelination GO:0031643 5 0.013
response to peptide GO:1901652 136 0.013
regulation of system process GO:0044057 200 0.013
limb development GO:0060173 166 0.013
negative regulation of protein modification process GO:0031400 163 0.013
positive regulation of cell death GO:0010942 224 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
respiratory system development GO:0060541 190 0.012
inflammatory response GO:0006954 244 0.012
regulation of ion transport GO:0043269 215 0.012
regulation of kinase activity GO:0043549 249 0.012
response to interferon alpha GO:0035455 7 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
cell division GO:0051301 120 0.012
hormone metabolic process GO:0042445 86 0.012
production of small rna involved in gene silencing by rna GO:0070918 6 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
dna recombination GO:0006310 92 0.012
positive regulation of cell killing GO:0031343 33 0.012
lipid biosynthetic process GO:0008610 179 0.012
stress activated mapk cascade GO:0051403 80 0.012
mitotic cell cycle process GO:1903047 159 0.012
blood vessel morphogenesis GO:0048514 285 0.012
regulation of defense response to bacterium GO:1900424 3 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.012
double strand break repair GO:0006302 48 0.012
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.012
response to growth factor GO:0070848 198 0.012
intracellular receptor signaling pathway GO:0030522 74 0.012
regulation of protein targeting GO:1903533 61 0.012
mitochondrion organization GO:0007005 134 0.012
limb morphogenesis GO:0035108 149 0.012
multi multicellular organism process GO:0044706 109 0.012
regulation of actin filament based process GO:0032970 99 0.012
regulation of anatomical structure size GO:0090066 178 0.012
regulation of cellular response to stress GO:0080135 159 0.012
rho protein signal transduction GO:0007266 32 0.012
regulation of nucleocytoplasmic transport GO:0046822 73 0.012
regulation of protein processing GO:0070613 96 0.012
regulation of myeloid cell differentiation GO:0045637 96 0.012
cellular modified amino acid metabolic process GO:0006575 63 0.012
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 10 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
activation of cysteine type endopeptidase activity GO:0097202 27 0.012
negative regulation of intracellular transport GO:0032387 38 0.011
schwann cell differentiation GO:0014037 26 0.011
covalent chromatin modification GO:0016569 163 0.011
leukocyte homeostasis GO:0001776 79 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
response to endoplasmic reticulum stress GO:0034976 53 0.011
lymphocyte proliferation GO:0046651 164 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
gliogenesis GO:0042063 141 0.011
regulation of cellular amine metabolic process GO:0033238 20 0.011
connective tissue development GO:0061448 179 0.011
gtp catabolic process GO:0006184 143 0.011
positive regulation of protein modification process GO:0031401 299 0.011
mrna metabolic process GO:0016071 84 0.011
endocytosis GO:0006897 168 0.011
defense response to protozoan GO:0042832 25 0.011
positive regulation of multi organism process GO:0043902 26 0.011
regulation of myd88 dependent toll like receptor signaling pathway GO:0034124 2 0.011
regulation of protein localization to nucleus GO:1900180 60 0.011
respiratory tube development GO:0030323 167 0.011
chemokine production GO:0032602 34 0.011
regulation of interferon beta biosynthetic process GO:0045357 4 0.011
type i interferon signaling pathway GO:0060337 10 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.011
interferon alpha production GO:0032607 7 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
defense response to gram positive bacterium GO:0050830 50 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
methylation GO:0032259 134 0.011
positive regulation of growth GO:0045927 104 0.011
antimicrobial peptide production GO:0002775 2 0.011
negative regulation of cell cycle GO:0045786 123 0.011
mda 5 signaling pathway GO:0039530 1 0.011
sensory perception GO:0007600 245 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
meiotic cell cycle GO:0051321 122 0.011
anatomical structure homeostasis GO:0060249 145 0.011
regulation of homeostatic process GO:0032844 182 0.011
epithelial cell proliferation GO:0050673 174 0.011
rhythmic process GO:0048511 174 0.011
regulation of protein import into nucleus GO:0042306 52 0.011
actin filament polymerization GO:0030041 44 0.011
negative regulation of glial cell proliferation GO:0060253 4 0.011
positive regulation of b cell activation GO:0050871 49 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
alcohol metabolic process GO:0006066 116 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.011
positive regulation of cell development GO:0010720 237 0.010
nucleoside phosphate biosynthetic process GO:1901293 79 0.010
striated muscle tissue development GO:0014706 293 0.010
regulation of organ morphogenesis GO:2000027 144 0.010
muscle cell development GO:0055001 133 0.010
regulation of viral entry into host cell GO:0046596 12 0.010
renal system development GO:0072001 225 0.010
negative regulation of cytoplasmic transport GO:1903650 29 0.010
cellular response to type i interferon GO:0071357 10 0.010
regulation of body fluid levels GO:0050878 162 0.010
positive regulation of t cell activation GO:0050870 101 0.010

Herc6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
organ system cancer DOID:0050686 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
cancer DOID:162 0 0.026
immune system disease DOID:2914 0 0.012
disease of anatomical entity DOID:7 0 0.012
disease of metabolism DOID:0014667 0 0.011
nervous system disease DOID:863 0 0.011